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Dissertations / Theses on the topic 'Skeletal muscle system'

Author: Grafiati

Published: 4 June 2021

Last updated: 14 February 2022

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1

Shue, Guay-Haur. "System models of skeletal muscle." Case Western Reserve University School of Graduate Studies / OhioLINK, 1995. http://rave.ohiolink.edu/etdc/view?acc_num=case1058448071.

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2

Peoples, Gregory Edward. "Skeletal muscle fatigue can omega-3 fatty acids optimise skeletal muscle function? /." Access electronically, 2004. http://www.library.uow.edu.au/adt-NWU/public/adt-NWU20041217.123607.

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Thesis (Ph.D.)--University of Wollongong, 2004.<br>Typescript. This thesis is subject to a 12 month embargo (06/09/05 - 14/09/05) and may only be viewed and copied with the permission of the author. For further information please contact the Archivist. Includes bibliographical references: leaf 195-216.

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3

Fry, William Mark. "K+ channels in Xenopus skeletal muscle /." St. John's NF : [s.n.], 2001.

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4

Watt, Kevin. "Regualtion of myogenesis and skeletal muscle size by the myostatin-Smad and mammalian Hippo signalling transduction pathways." Available from the University of Aberdeen Library and Historic Collections Digital Resources, 2009. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?application=DIGITOOL-3&owner=resourcediscovery&custom_att_2=simple_viewer&pid=62160.

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5

Abraham, Kirk A. "Inorganic phosphate uptake in rat skeletal muscle." Free to MU campus, others may purchase, 2003. http://wwwlib.umi.com/cr/mo/fullcit?p3115518.

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6

Watt, Kevin. "Regulation of myogenesis and skeletal muscle size by the myostatin-Smad and mammalian Hippo signalling transduction pathways." Thesis, University of Aberdeen, 2009. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=62160.

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The aims of this thesis were to 1) investigate the effect of SB431542 <i>in vitro</i> and <i>ex vivo</i> as a novel approach towards promoting the functional hypertrophy of skeletal muscle by inhibiting the myostatin-Smad pathway, 2) to investigate the expression and function of the Yes-associated protein (Yap) in skeletal muscle and C2C12 cells as a novel regulator of C2C12 differentiation and 3) to generate a GFP-RCASBP-hYAP1 S127A retrovirus to allow the study of the function of Yap in skeletal muscle differentiation <i>in vivo</i>. The results presented in this thesis show that SB431542 pr

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7

Boyle, Kristen E. Houmard Joseph A. "Metabolic inflexibility in skeletal muscle with obesity." [Greenville, N.C.] : East Carolina University, 2009. http://hdl.handle.net/10342/1904.

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Thesis (Ph.D.)--East Carolina University, 2009.<br>Presented to the faculty of the Department of Exercise and Sports Science. Advisor: Joseph A. Houmard. Title from PDF t.p. (viewed Apr. 30, 2010). Includes bibliographical references.

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8

Skeer, Jacqueline Mary. "Calcium channels of insect nervous system and skeletal muscle." Thesis, University of Cambridge, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.239592.

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9

Markert, Chad D. "Ultrasound and exercise in skeletal muscle regeneration." Connect to this title online, 2004. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1091304498.

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Thesis (Ph. D.)--Ohio State University, 2004.<br>Document formatted into pages. Includes bibliographical references. Abstract available online via OhioLINK's ETD Center; full text release delayed at author's request until 2005 Aug. 2.

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10

Bhalla, Ashish. "Skeletal muscle modulation and functional recovery after colonic resection." Thesis, University of Nottingham, 2016. http://eprints.nottingham.ac.uk/32130/.

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Introduction: Colorectal cancer surgery involves a period of recovery in hospital followed by convalescence at home. Enhanced recovery programs, in particular the use of laparoscopic surgery have reduced length of inpatient stay. Knowledge regarding the impact of surgery upon functional recovery is lacking. Loss of lean muscle mass and strength may compromise function. We conducted two studies (1) To assess skeletal muscle modulation and functional recovery after potentially curative colon cancer surgery, comparing traditional open surgery (OS) with laparoscopic (LS) techniques and (2) To revi

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11

Judson, Robert Neil. "The role of Yes-associated protein (YAP) in skeletal muscle satellite cells and myofibres." Thesis, University of Aberdeen, 2012. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=189444.

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In spite of its post mitotic nature, skeletal muscle maintains remarkable plasticity. Muscle fibres (myofibres) are capable of large alterations in their size as well as an enormous ability to regenerate following injury – thanks to a potent population of resident stem cells (satellite cells). Deciphering the molecular signalling networks responsible for skeletal muscle growth and regeneration is of key scientific interest – not least because of the therapeutic potential these pathways may hold for the treatment of diseases such as muscular dystrophy. In this thesis, the transcriptional co-fac

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12

Hall, Israel Restus. "Spectral analysis and regularity quantification of skeletal muscle signals as a non-invasive assessment of muscle." Morgantown, W. Va. : [West Virginia University Libraries], 2004. https://eidr.wvu.edu/etd/documentdata.eTD?documentid=3660.

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Thesis (M.S.)--West Virginia University, 2004.<br>Title from document title page. Document formatted into pages; contains viii, 119 p. : ill. (some col.). Includes abstract. Includes bibliographical references (p. 97-101).

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13

Hoy, Andrew James. "Nutritive and non-nutritive blood flow in skeletal muscle." Department of Biomedical Science - Faculty of Health & Behavioural Sciences, 2004. http://ro.uow.edu.au/theses/232.

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The vascular structure of mammalian skeletal muscle has been intensively investigated for the last seventy years. Since the early work of Pappenheimer and Barlow, the existence of a parallel dual vascular pathway has been suggested to explain the differences between total flow and clearance rates of a variety of infused substances. Direct microscopy studies using superficial muscles have shown that the microvascular arterioles have very frequent connections with the capillary modules of the associated connective tissue and adipose tissue within skeletal muscle. In more recent times, Clark and

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14

Wise, Andrew 1972. "Skeletal muscle : activation strategies, fatigue properties and role in proprioception." Monash University, Dept. of Physiology, 2001. http://arrow.monash.edu.au/hdl/1959.1/8355.

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15

Lunn, Elizabeth Ruth. "Studies on the degeneration and regeneration of neurons to skeletal muscle." Thesis, University of Oxford, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.292675.

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16

Pang, Zhiyu. "Functions of the ubiquitin system in mammalian spermatogenesis and skeletal muscle." Thesis, McGill University, 2011. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=96699.

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The conjugation of ubiquitin to proteins is catalyzed sequentially by a cascade of members of three classes of enzymes – ubiquitin activating enzyme (E1), ubiquitin conjugating enzyme (E2), and ubiquitin protein ligase (E3). Polyubiquitinated protein substrates are selectively targeted for degradation by the proteasome. Removal of ubiquitin from ubiquitinated substrates is catalyzed by deubiquitinating enzymes (DUB). In this thesis, I have explored functions of three specific enzymes of the ubiquitin system, the E2 UBC4-testis, the HECT E3 EDD/Rat100 and the deubiquitinating enzyme USP19, in m

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17

Bass, Joseph. "The role of the vitamin D receptor in skeletal muscle protein metabolism." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/40166/.

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18

Kohn, Tertius A. "Characteristics and adaptation of skeletal muscle to endurance exercise." Thesis, Stellenbosch : University of Stellenbosch, 2011. http://hdl.handle.net/10019.1/16517.

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Thesis (PhD)--University of Stellenbosch, 2005.<br>ENGLISH ABSTRACT: Skeletal muscle adapts to stimuli by modifying structural and metabolic protein expression. Furthermore, a muscle group may vary within itself to accommodate specialisation in regions. Structural and metabolic characteristics of an individual are regulated partly by genotype, but contraction duration and intensity may play a greater role in muscle phenotype. The aims of this dissertation were to investigate: structural and metabolic regionalisation in a muscle group, possible relationships between training volume and int

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19

Berg, Ulrika. "The IGF-IGFBP system in aerobic exercise - with focus on skeletal muscle /." Stockholm : Institutionen för kvinnors och barns hälsa, Karolinska institutet, 2007. http://diss.kib.ki.se/2007/978-91-7357-379-5/.

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20

Jones, Simon W. "Fibre-type specific expression of the calpain proteolytic system in skeletal muscle." Thesis, University of Nottingham, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.312237.

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21

Mohan, Divya. "Systemic inflammation in COPD : effects on skeletal muscle and the cardiovascular system." Thesis, Imperial College London, 2016. http://hdl.handle.net/10044/1/55255.

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Chronic obstructive pulmonary disease (COPD) is increasingly recognised to be heterogeneous and complex, with several extra-pulmonary manifestations, necessitating categorisation of patients in order to better tailor treatments towards distinct phenotypes. Cardiovascular disease and peripheral skeletal muscle dysfunction are amongst the most important comorbidities in COPD, with systemic inflammation proposed as a potential mechanistic link. Therefore, there is considerable interest in novel anti-inflammatory drugs, as well as understanding underlying mechanisms. An observational study of 729

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22

Struthers, Kyle Remington. "ISCHEMIA IMPAIRS VASODILATION IN SKELETAL MUSCLE RESISTANCE ARTERY." DigitalCommons@CalPoly, 2011. https://digitalcommons.calpoly.edu/theses/546.

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Functional vasodilation in arterioles is impaired with chronic ischemia. We sought to examine the impact of chronic ischemia and age on skeletal muscle resistance artery function. To examine the impact of chronic ischemia, the femoral artery was resected from young (2-3mo) and adult (6-7mo) mice and the profunda femoris artery diameter was measured at rest and following gracilis muscle contraction 14 days later using intravital microscopy. Functional vasodilation was significantly impaired in ischemic mice (14.4±4.6% vs. 137.8±14.3%, p<0.0001 n=8) and non-ischemic adult mice (103.0±9.4% vs. 13

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23

Carroll, Chad C. "Skeletal muscle function and myosin heavy chain expression with Multiple Sclerosis." Virtual Press, 2001. http://liblink.bsu.edu/uhtbin/catkey/1221317.

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The purpose of this investigation was to examine the effects of Multiple Sclerosis (MS) on the structural and functional characteristics of skeletal muscle. More specifically, we analyzed the myosin heavy chain (MHC) and fiber type distribution of the vastus lateralis, measured single fiber cross sectional area (CSA), and determined the isokinetic and isotonic strength of the knee extensor muscles. Six sedentary subjects with MS (age: 44 ± 2 yrs) and six sedentary gender-matched controls (age: 46 ± 4) were evaluated. EachMS subject was rated on the Kurtzke's Expanded Disability Status Scale (E

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24

Maladen, Ryan D. "Effect of stimulation train characteristics on the dynamic performance of human skeletal muscle." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file 0.38 Mb., 57 p, 2006. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:1435807.

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25

Pattison, J. Scott. "Understanding muscle wasting through studies of gene expression and function." Free to MU Campus, others may purchase, 2004. http://wwwlib.umi.com/cr/mo/fullcit?p3164536.

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26

Owino, Dorcas Vivian Apiyo. "Evaluation of role of paracrine/autocrine IGF-1 system in skeletal muscle adaptation." Thesis, University College London (University of London), 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.406510.

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27

Forshaw, P. J. "Effects of pyrethroids on the cardiovascular system and skeletal muscle in the rat." Thesis, University of Cambridge, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.377566.

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28

Chou, Li-Wei. "New strategies to maintain paralyzed skeletal muscle force output during repetitive electrical stimulation." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 147 p, 2007. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:3247571.

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29

Acharyya, Swarnali. "Elucidating molecular mechanisms of muscle wasting in chronic diseases." Columbus, Ohio : Ohio State University, 2007. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1180096565.

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30

Wang, Mengxi. "Role of Map4k4 in Skeletal Muscle Differentiation: A Dissertation." eScholarship@UMMS, 2013. http://escholarship.umassmed.edu/gsbs_diss/675.

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Skeletal muscle is a complicated and heterogeneous striated muscle tissue that serves critical mechanical and metabolic functions in the organism. The process of generating skeletal muscle, myogenesis, is elaborately coordinated by members of the protein kinase family, which transmit diverse signals initiated by extracellular stimuli to myogenic transcriptional hierarchy in muscle cells. Mitogen-activated protein kinases (MAPKs) including p38 MAPK, c-Jun N terminal kinase (JNK) and extracellular signal-regulated protein kinase (ERK) are components of serine/threonine protein kinase cascades th

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31

Kesar, Trisha. "Effect of stimulation frequency and intensity on skeletal muscle fatigue during repetitive electrical stimulation." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file 1.62 Mb., 85 p, 2006. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:1430768.

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32

De, Bie Gabrielle. "The effects of acute hypoxia on metabolic enzymes in skeletal muscle." Thesis, Stellenbosch : University of Stellenbosch, 2006. http://hdl.handle.net/10019.1/3401.

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Thesis (MPhil (Physiological Sciences))--University of Stellenbosch, 2006.<br>The responses of central systems to oxygen deprivation have been well characterised while adaptations in peripheral systems, such as skeletal muscles, have presented confounding variations. Several reasons for these discrepancies are purported, amongst them being the duration of exposure to hypoxia and variations in fibre composition. Moreover, in real-life high altitude situations there may be a combination of factors which have the ability to modify or alter the effect of hypoxia. This study investigates the effect

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33

Hardy, Kristin M. "A reaction-diffusion analysis of cellular design and function in skeletal muscle." View electronic thesis (PDF), 2009. http://dl.uncw.edu/etd/2009-1/hardyk/kristinhardy.pdf.

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34

McGlory, C. "The impact of n-3 PUFA supplementation on human skeletal muscle metabolism." Thesis, University of Stirling, 2014. http://hdl.handle.net/1893/19975.

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The time course of this increase in muscle n-3 PUFA composition and anabolic protein expression is currently unknown. In Chapter 2 of this thesis ten healthy male participants consumed 5g.d-1 of n-3 PUFA-enriched fish oil for 4 weeks. Muscle biopsies samples were collected in the fasted, rested state 2 weeks prior, immediately before (Week 0), at Week 1, Week 2 and Week 4 after initiation of fish oil supplementation for assessment of changes in lipid composition and expression of anabolic signalling proteins over time. Muscle lipid profile, (% total n-3 PUFA/total fatty acids) increased from W

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35

Carriou, Vincent. "Multiscale, multiphysic modeling of the skeletal muscle during isometric contraction." Thesis, Compiègne, 2017. http://www.theses.fr/2017COMP2376/document.

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Les systèmes neuromusculaire et musculosquelettique sont des systèmes de systèmes complexes qui interagissent parfaitement entre eux afin de produire le mouvement. En y regardant de plus près, ce mouvement est la résultante d'une force musculaire créée à partir d'une activation du muscle par le système nerveux central. En parallèle de cette activité mécanique, le muscle produit aussi une activité électrique elle aussi contrôlée par la même activation. Cette activité électrique peut être mesurée à la surface de la peau à l'aide d'électrode, ce signal enregistré par l'électrode se nomme le signa

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36

Hershey, John Davidson. "Minimal disuse muscle atrophy and seasonal alterations in the calcium handling system in skeletal muscle of hibernating brown bears." Pullman, Wash. : Washington State University, 2008. http://www.dissertations.wsu.edu/Dissertations/Fall2008/J_Hershey_020309.pdf.

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37

Wilkin, Linda Diane. "Rehabilitative influence of therapeutic ultrasound treatment on cellular markers of skeletal muscle regeneration following blunt contusion injury /." The Ohio State University, 2002. http://rave.ohiolink.edu/etdc/view?acc_num=osu1486463321624146.

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38

Kenyani, Jenna. "A system wide study on the hypertrophic response to salbutamol in skeletal muscle cells." Thesis, University of Liverpool, 2012. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.632652.

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Salbutamol was synthesised in 1967 and is widely known now as a Beta-adrenergic agonist. It is known that p-agonists cause hypertrophy in various mammalian muscles cells, however the mechanisms by which this occurs are not fully understood. Recent studies have suggested that there is great potential for using Beta-agonists, specifically Beta-agonists, in restoring muscle mass and strength in humans. Although, salbutamol is commonly used as a bronchodilator, it has heen identified as having an effect on muscle growth at a dose which is safe for humans. However, like all steroids there are many

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39

Zhou, Hehe. "A novel method to measure finite strain fields in human skeletal muscles with cine phase contrast MRI in vivo, non-invasively and dynamically." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 207 p, 2006. http://proquest.umi.com/pqdweb?did=1172112541&sid=3&Fmt=2&clientId=8331&RQT=309&VName=PQD.

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40

Kalezić, Nebojša. "Autonomic reactivity in muscle pain : clinical and experimental assessment /." Umeå : Univ, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-919.

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41

Brault, Jeffrey J. "Creatine uptake and creatine transporter expression among rat skeletal muscle fiber types." free to MU Campus, others may purchase, 2003. http://wwwlib.umi.com/cr/mo/fullcit?p3091902.

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42

Renström, Lina. "The involvement of the TNF-alpha system in skeletal muscle in response to marked overuse." Doctoral thesis, Umeå universitet, Anatomi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-141942.

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Painful conditions having the origin within the musculoskeletal system is a common cause for people to seek medical care. Between 20-40% of all visits to the primal care in Sweden are coupled to pain from the musculoskeletal system. Muscle pain and impaired muscle function can be caused by muscles being repetitively overused and/or via heavy load. Skeletal muscle is a dynamic tissue which can undergo changes in order to fulfill what is best for optimal function. However, if the load is too heavy, morphological changes including necrosis, as well as pain can occur. The extension of the skeletal

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43

Schulze, Kimberley E. "A minimalistic model of resistance training : effects on skeletal muscle function during unloading." Virtual Press, 1999. http://liblink.bsu.edu/uhtbin/catkey/1170962.

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Since astronaut time and energy are at a premium, effective countermeasures must be designed to maximize benefits while minimizing time/energy cost. Therefore, our intent was to design and evaluate a low volume, high intensity resistance training program (RTP) on the preservation of knee extensor and plantar flexor size, strength and neuromuscular function in response to unloading. A total of 32 subjects participated. Sixteen men underwent 21 days of unilateral lower limb suspension (ULLS) and were assigned to control (no RTP) (ULLS-CON, n=8) or countermeasures (ULLS-CM, n=8). The remaining su

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44

Dornan, Thomas J. "Antioxidant Anthocyanidins and Calcium Transport Modulation of the Ryanodine Receptor of Skeletal Muscle (RyR1)." PDXScholar, 2011. https://pdxscholar.library.pdx.edu/open_access_etds/319.

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Cardiovascular disease (CVD) claims more lives than any other disease in the world. Although numerous biological pathways share the blame, ventricular tachyarrhythmia (VT) is estimated to account for ~25% of all CVD deaths. A complete understanding of the molecular mechanisms underlying VT is unknown but recent studies have linked VT to improper calcium handling in the heart (canine). The principle calcium regulator in the muscle cell is the calcium ion release channel (aka RyR). Numerous endogenous and exogenous compounds can affect the way the RyR regulates calcium. In particular, abnormal l

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45

Scriba, E. W. (Ernst Wolfgang). "Proximal feed artery regulation of skeletal muscle blood flow during exercise : the paraplegic model." Thesis, Stellenbosch : Stellenbosch University, 2003. http://hdl.handle.net/10019.1/49783.

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Assignment (MPhil)--University of Stellenbosch, 2003.<br>ENGLISH ABSTRACT: The mechanisms of blood flow (BF) control to skeletal muscle during dynamic exercise are still not clearly understood. The paraplegic subject (P) has reduced sympathetic innervation to the lower limbs. The current study was designed to focus on the contribution of neural control, specifically the sympathetic nervous system (SNS), as part of the central vascular mechanism to skeletal muscle BF during dynamic exercise. Aims: We studied BF parameters in P vs. able-bodied subjects (AB) to determine whether the parapl

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46

Vinnakota, Kalyan Chakravarthy. "pH dynamics, glycogenolysis and phosphoenergetics in isolated cell free reconstituted systems and in mouse skeletal muscle /." Thesis, Connect to this title online; UW restricted, 2006. http://hdl.handle.net/1773/8034.

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47

Fagergren, Anders. "A multidisciplinary system identification of the human precision grip /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-632-4.

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48

Hunt, Desmond Gerard. "The role of [beta]-adrenergic receptors in regulating skeletal muscle glucose utilization at rest and during exercise /." Full text (PDF) from UMI/Dissertation Abstracts International, 2001. http://wwwlib.umi.com/cr/utexas/fullcit?p3008356.

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49

Brook, Matthew. "Development and application of novel stable isotopic approaches to study human skeletal muscle in response to exercise and ageing." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/39824/.

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50

Balch, Maria Helen Harley. "Acute Mechanisms of Skeletal Muscle Decline and Rehabilitative Recovery Following Ischemic Stroke." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu159558748119711.

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