Relevant bibliographies by topics / Ski bindings

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Ski bindings'

Author: Grafiati
Published: 4 June 2021
Last updated: 18 February 2022

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Journal articles on the topic "Ski bindings"

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Campbell, Jeffrey R., Irving S. Scher, David Carpenter, Bruce L. Jahnke, and Randal P. Ching. "Performance of Alpine Touring Boots When Used in Alpine Ski Bindings." Journal of Applied Biomechanics 33, no. 5 (October 1, 2017): 330–38. http://dx.doi.org/10.1123/jab.2016-0256.

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Alpine touring (AT) equipment is designed for ascending mountains and snow skiing down backcountry terrain. Skiers have been observed using AT boots in alpine (not made for Alpine Touring) ski bindings. We tested the effect on the retention-release characteristics of AT boots used in alpine bindings. Ten AT ski boots and 5 alpine ski boots were tested in 8 models of alpine ski bindings using an ASTM F504-05 (2012) apparatus. Thirty-one percent of the AT boots released appropriately when used in alpine ski bindings. One alpine binding released appropriately for all alpine and AT boots tested; 2 alpine ski bindings did not release appropriately for any AT boots. Altering the visual indicator settings on the bindings (that control the release torque of an alpine system) had little or no effect on the release torque when using AT boots in alpine ski bindings. Many combinations released appropriately in ski shop tests, but did not release appropriately in the more complex loading cases that simulated forward and backward falls; the simple tests performed by ski shops could produce a “false-negative” test result. These results indicate that using AT boots with alpine ski bindings could increase the likelihood of lower leg injuries.
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Natri, Antero, Bruce D. Beynnon, Carl F. Ettlinger, Robert J. Johnson, and Jasper E. Shealy. "Alpine Ski Bindings and Injuries." Sports Medicine 28, no. 1 (1999): 35–48. http://dx.doi.org/10.2165/00007256-199928010-00004.

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Suderman, Bethany L., Alexander Sklar, Lenka L. Stepan, and Irving S. Scher. "Water Ski Binding Release Characteristics in Forward Lean." Proceedings 49, no. 1 (June 15, 2020): 76. http://dx.doi.org/10.3390/proceedings2020049076.

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To reduce the risk of injury, waterski bindings should secure the foot to the ski when the likelihood of lower leg injury is low (retention) and free the foot when the likelihood of injury is high (release). Unlike snow skiing, there are no standards dictating the release of waterski bindings. Testing was completed to determine release torques in forward lean of three commercially available waterski boot-binding systems. Each binding was mounted to a 66-inch waterski and the boot was fitted on a lower leg surrogate with a torque transducer. A forward-lean bending moment was applied quasi-statically about the transverse axis of the ski until the binding released the boot. For the three boot-binding systems, the range of release torques were 126 to 219, 50 Nm to 141, and 63 to 127 Nm.
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Graf, Simon, Stefan Litzenberger, and Anton Sabo. "Edging stiffness of ski touring bindings." Procedia Engineering 13 (2011): 37–43. http://dx.doi.org/10.1016/j.proeng.2011.05.048.

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Ettlinger, Carl F., David Dodge, Robert J. Johnson, Jasper E. Shealy, Michael Sargent, R. J. Johnson, J. Stealy, V. Senner, and S. W. Dean. "Retention Requirements for Alpine Ski Bindings." Journal of ASTM International 7, no. 6 (2010): 102978. http://dx.doi.org/10.1520/jai102978.

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Wunderly, Glenn S., and Maury L. Hull. "A Biomechanical Approach to Alpine Ski Binding Design." International Journal of Sport Biomechanics 5, no. 3 (August 1989): 308–23. http://dx.doi.org/10.1123/ijsb.5.3.308.

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A new approach to ski binding design is advanced. It begins with a release locus derived from injury mechanics research and knowledge of the expected loading conditions and then incorporates these into the final binding design. A mechanical ski binding designed by following the new approach is presented. This binding offers a number of performance features not found in commercially available designs. One feature is the ability to eliminate the axial force supported by the tibial shaft from affecting release in forward bending. A second feature is the binding’s ability to release according to virtually any preprogrammed locus of the combination of moments in both bending and torsion. A third feature is a release mechanism that is insensitive to the common frictional forces that affect the release consistency of conventional heel/toe bindings. In addition to these features, the binding offers a variety of operational conveniences. The presentation of the binding not only describes the design details but also evaluates the release performance (i.e., locus and consistency) based upon laboratory tests under quasistatic loading.
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Boldrino, Christian, Bob Goethals, and Renate Wachter-Fritz. "The actual release-values of ski safety-bindings on ski-runs in Austria." International Journal for Consumer and Product Safety 3, no. 1 (March 1996): 39–46. http://dx.doi.org/10.1080/09298349608945763.

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Mote, C. D. "The Forces of Skiing and Their Implication to Injury." International Journal of Sport Biomechanics 3, no. 4 (November 1987): 309–25. http://dx.doi.org/10.1123/ijsb.3.4.309.

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The forces and moments applied to the leg by the ski during skiing are compared to the forces necessary to cause injury to the tibia and ligaments at the knee and to standard recommendations for ski release binding adjustment. These forces and moments of recreational skiing are shown to be similar to, or greater than, those capable of causing injury to the knee and tibia. The adjustment of release bindings by current standards unavoidably permits forces of sufficient magnitude to cause injury to the skier. Release bindings cannot be adjusted to guarantee that the forces transmitted to the boot are below an injury threshold for a large fraction of the population. The role of muscle contraction in skiing safety requires complete recognition in the knowledge base on skiing safety.
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Hull, M. L., M. Swanstrom, and B. Wade. "Electromechanical Ski Release Binding With Mechanical Backup." Journal of Mechanical Design 119, no. 1 (March 1, 1997): 145–48. http://dx.doi.org/10.1115/1.2828779.

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To better protect Alpine skiers against injuries to both the lower leg and the knee, the objective of this work was to design a binding which: (1) maintained a consistent release level in twist in the presence of combined loads; (2) released the heelpiece based on the anterior/posterior (A/P) bending moment transmitted by the leg; and (3) modulated the release level in twist depending on the degree of contraction in muscles crossing the knee. To fulfill the objective, a conventional ski binding was modified. Modifications included integrating dynamometers into the toepiece, anti-friction device (AFD), and heelpiece. The toepiece sensor indicates the twisting moment while the AFD and heelpiece sensors indicate the anterior bending moment transmitted by the leg. To gain electronic control of binding release, a solenoid actuated mechanism was added which translated the heelpiece rearward along the ski to decouple the boot from the binding. Otherwise, the binding allowed normal mechanical function. Prototype testing confirmed the ability of the dynamometers to accurately measure desired loads in the presence of extraneous loads and the reliability of the solenoid actuated mechanism in releasing the hoot under loads typical of skiing. Thus, this work demonstrated the feasibility of hybrid electromechanical/mechanical releasable bindings. Such a demonstration should encourage the development of designs for commercial use.
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Nusser, Michaela, Aljoscha Hermann, and Veit Senner. "Artificial Knee Joint and Ski Load Simulator for the Evaluation of Knee Braces and Ski Bindings." Procedia Engineering 147 (2016): 220–27. http://dx.doi.org/10.1016/j.proeng.2016.06.217.

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Dissertations / Theses on the topic "Ski bindings"

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Low, Tyrone. "The Development of a Low Profile Alpine Touring Binding." Thesis, University of Canterbury. Mechanical Engineering, 2010. http://hdl.handle.net/10092/5198.

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The design of alpine touring ski bindings has remained relatively static for the past fifteen years. During this period, the lack of innovative breakthroughs has become obvious through the number of customers who are currently unsatisfied by the products available on the market. This observation has presented a significant commercial opportunity to satisfy these users, plus many more non-consumers, with an innovative binding design. The objective of this project was to design a low profile alpine touring binding with the aim of satisfying the needs of these users. The resulting design followed a full year of research and development in the field of alpine touring bindings. Not only were concepts formed from completely untethered and open minded thinking, but they were also formed from reviewing various designs that already existed. These designs ranged from previous alpine touring bindings that either failed or succeeded in the market for various reasons, to completely unrelated mechanisms and designs forms. Through this process, several well formed and feasible design concepts were obtained which potentially met the design specification requirements of both high performing alpine touring bindings and downhill bindings. Detailed design and analysis followed, along with the manufacture of a fully functional prototype. This was then tested and evaluated to determine the project as a success. This project can be grouped only with a small amount of research ever conducted on the topic of alpine touring bindings. The findings, discussion and results of this work can therefore be used as a benchmark for future study into this field. Through the meticulous research conducted on skiing and ski bindings and the thorough design work carried out towards producing a prototype, this thesis presents the complete process of designing a new and innovative ski binding.
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Lundin, Felix. "Design of workstation for binding adjustment in ski rental shops." Thesis, Luleå tekniska universitet, Institutionen för ekonomi, teknik, konst och samhälle, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-82835.

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This master thesis project was a part of the education Master of science in Industrial Design Engineering at Luleå University of Technology with the mission of developing a work desk that suits in to the client company NoMoreBoots range of ski rental products. The background of the project was that work desks that are used mainly with the purpose of adjusting alpine ski bindings in ski rental shops often are primitive home constructions and other manufacturers work desks with the same purpose do not have enough advantages compared to the self-built ones to be worth the extra costs. With a new kind of tool introduced in the industry that facilitates the adjustments of alpine ski bindings came an opportunity to design the work desk in a new way. The work process has followed the user-centered design framework Double Diamond which consists of the phases: discover, define, develop and deliver. After exploring of the context with interviews and benchmarking, the projects main focus became at the ergonomic conditions and how it could be improved for the staff as it was the need identified that had the most protentional of improvements for the user. Literature studies, different types of idea generating methods and evaluations have been conducted to come up with a result that meet the needs of the users. The project resulted in a CAD model of a compact work desk that has a height adjustment mechanisk to enable the user to work with a good ergonomic position in several different work tasks.
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Rupert, Peter Benjamin. "Structure determination of the SKN-1 DNA binding domain complex /." view abstract or download file of text, 1999. http://wwwlib.umi.com/cr/uoregon/fullcit?p9947981.

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Thesis (Ph. D.)--University of Oregon, 1999.
Typescript. Includes vita and abstract. Includes bibliographical references (leaves 96-106). Also available for download via the World Wide Web; free to University of Oregon users. Address: http://wwwlib.umi.com/cr/uoregon/fullcit?p9947981.
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Xu, Su. "Insulin-like growth factors and their binding proteins in human skin." Thesis, University of Bristol, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.343351.

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Thompson, Elizabeth Ellen Anderson. "CCAAT/Enhancer Binding Protein Alpha in UVB Responses in Human and Mouse Skin and Mouse Skin Tumorigenesis." NCSU, 2009. http://www.lib.ncsu.edu/theses/available/etd-07062009-002822/.

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Human epidermis is routinely subjected to DNA damage induced by solar radiation and keratinocytes have developed intricate mechanisms to respond to UVB-induced DNA damage. Despite these mechanisms, nonmelanoma skin cancer is the most common cancer in the US. Previous analysis of immortalized mouse keratinocytes has revealed that the bZIP transcription factor, CCAAT/enhancer binding protein alpha (C/EBP alpha), is induced by DNA damage and has a role in the G1 checkpoint. Here we demonstrate C/EBP alpha is induced in the epidermis of the human subjects exposed to UVB. To begin to determine the in vivo physiological significance of the up-regulation of C/EBP alpha by UVB, we generated an epidermal specific C/EBP alpha knockout (K5Cre;C/EBP alpha fl/fl) mouse on a SKH1 hairless background. Following UVB treatment, these mice displayed an impaired keratinocyte cycle arrest and abnormal entry of keratinocytes into S-phase. This impaired cell cycle checkpoint in UVB-treated C/EBP alphaï deficient skin was associated with greatly diminished p21 levels which occurred through a p53-independent mechanism. To further investigate whether C/EBP alpha could function as a tumor suppressor gene in UVB induced skin tumorigenesis, we exposed K5Cre;C/EBP alpha fl/fl and K5Cre control SKH1 mice to 20mJ/cm2 UVB three times weekly. The K5Cre;C/EBP alpha fl/fl mice displayed both increased tumor incidence and multiplicity, suggesting that loss of C/EBP alpha in the epidermis confers increased susceptibility to UVB-induced skin tumorigenesis. In addition, we also observed that human skin SCC and BCC display greatly reduced or absent C/EBP alpha levels, implicating that loss of C/EBP alpha contributes to the development of human nonmelanoma skin cancers. Collectively, our results demonstrate that C/EBP alpha is induced by UVB in human skin, inhibits cell cycle progression in response to UVB in vivo and is a tumor suppressor gene in UVB induced skin tumorigenesis.
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Albati, Amal Abdulah. "PURIFICATION OF RECOMBINANT δ NP63 α AND CHARACTERIZATION OF PEPTIDE BINDING." Wright State University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=wright1447223071.

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Haapaniemi, T. (Tarja). "Autonomic dysfunction in Parkinson's disease and its correlates to medication and dopamine transporter binding." Doctoral thesis, University of Oulu, 2001. http://urn.fi/urn:isbn:9514259637.

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Abstract Patients with idiopathic Parkinson's disease (PD) may suffer from autonomic nervous system dysfunction even in the early phase of the disease. We assessed the autonomic cardiovascular and sudomotor regulation in de novo PD patients with and without medication. We also measured the dopamine (DAT) and serotonin transporter (SERT) uptake in the PD patients using 2β-carboxymethoxy-3β-(4-iodophenyl)tropane (β-CIT) SPECT and studied the clinical correlates of the uptake. Sixty PD patients were included in the study and randomised to receive levodopa, bromocriptine or selegiline (n=20 in each) as their treatment. Thirty patients were examined with β-CIT SPECT. The results of the patients were compared with those of healthy controls and within the subgroups at different time points. Cardiovascular autonomic regulation was assessed using standard cardiovascular reflex tests at baseline, after six months' medication and following a 6-week washout period. The heart rate (HR) and blood pressure (BP) regulation was impaired in PD patients at baseline, and PD medications modified the responses further. Bromocriptine and selegiline, in contrast to levodopa, increased the orthostatic BP fall and suppressed the BP response to isometric exercise. The long-term cardiovascular autonomic function was evaluated from ambulatory ECG recordings by analysis of traditional spectral and non-spectral components of HR fluctuation together with two-dimensional vector analysis and power-law relationship analysis of the HR dynamics. All spectral measures and the slope of the power-law relationship demonstrated impaired tonic cardiovascular regulation in the PD patients. Sympathetic sudomotor activity was evaluated using the sympathetic skin response (SSR). The major finding was suppression of the SSR amplitudes with an inverse correlation to clinical disability, whereas PD medication seemed to have only minor effects. The changes in amplitude and repetitiveness of the SSRs with normal adaptation suggest deficits at several levels of the SSR reflex arc. DAT uptake, assessed by β-CIT SPECT, was diminished in the striatum and especially the putamen of the PD patients, and correlated with the results of the cardiovascular reflex tests and ambulatory ECG recordings. Simultaneous measurement of SERT binding demonstrated decreased SERT availability in the thalamic and frontal areas. The results demonstrate disturbances of the reflectory and tonic cardiovascular autonomic regulation caused by PD itself. PD medications further modify the reflectory responses. The degenerative process in PD also involves the sympathetic sudomotor pathway. β-CIT SPECT provides a useful method for simultaneous assessment of DAT and SERT binding, demonstrating the deficit of serotonin metabolism in PD.
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Atkins, Karen. "Structural and functional studies of bacterial adhesion proteins : Staphylococcus aureus immunoglobulin-binding proteins Sbi and SpA and their interactions with serum proteins." Thesis, University of Bath, 2006. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.432400.

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László, Csaba F. "Translation regulation of UV-light-induced transcription factor NF-kappa-B and oncogene COX-2." View abstract, 2009. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:3353542.

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Hyde, Carolyn Elizabeth. "The functional consequences of the interactions between insulin-like growth factors (IGFs), insulin-like growth factor binding proteins (IGFBPs) and vitronectin (VN) and their involvement in skin." Queensland University of Technology, 2006. http://eprints.qut.edu.au/16197/.

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The insulin-like growth factor (IGF) system plays an important role in a number of disease states, such as cancer, and has also been implicated in wound and burn healing processes. Two IGF receptors, the type-1 IGF and type-2 IGF receptors, as well as six insulin-like growth factor binding proteins (IGFBP-1 to 6), have well established roles in mediating IGF activity. Earlier studies in this laboratory demonstrated that IGF-II binds to the extracellular matrix (ECM) protein vitronectin (VN), and although IGF-I does not bind directly to VN it can bind indirectly via specific IGFBPs. Therefore the aim of the research described in this thesis was to determine whether binary and ternary complexes of IGF-I/II, IGFBPs and VN affect human keratinocyte cell function. The strategy of pre-binding these complexes to the culture dishes was adopted in this study in an attempt to more accurately reflect the extracellular environment in vivo. These studies demonstrated that the binary complex of IGF-II and VN and the ternary complexes comprised of IGF-I, IGFBP-2, or 3, or 4, or 5 and VN significantly stimulated HaCaT de novo cell protein synthesis in the human keratinocyte cell line. Interestingly, these latter experiments demonstrated that although large increases in protein synthesis were observed using the ternary complexes, IGF-I/IGFBP complexes alone were responsible for the significant increases in protein synthesis and these responses are mediated via the MAPK signaling pathway. In addition, both the dimeric and trimeric complexes significantly enhanced cell migration through 12 μm TranswellsTM. Unlike the protein synthesis assays, VN was critically important in these migratory responses and highlighting the important role that integrins play in cell migration. Cell attachment assays on the other hand demonstrated that the interactions of IGFs with IGFBPs and VN did not affect cell attachment. The data encompassed within this thesis represent the first studies to provide a functional role for the interaction between IGFs, IGFBPs and VN in human keratinocytes. Taken together these results suggest that IGF/IGFBP/VN complexes may hold great potential in situations where enhanced keratinocyte cell migration and proliferation is required, such as in wound healing and skin engineering applications.
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Books on the topic "Ski bindings"

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Cheung, Hermia. Effect of dopamine depletion on D1 receptor binding in rat brain; and metabolism studies of D1 agonist R-[11C]SKF 82957 and phosphodiesterase-4 inhibitor R-[11C}rolipram. Ottawa: National Library of Canada, 2003.

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Haddix, Margaret Peterson. Under Their Skin (Turtleback School & Library Binding Edition). Turtleback Books, 2017.

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The Adverse Outcome Pathway for Skin Sensitisation Initiated by Covalent Binding to Proteins. OECD, 2014. http://dx.doi.org/10.1787/9789264221444-en.

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Frairia, Roberto, and H. Leon Bradlow. Steroid-Protein Interactions: Basic and Clinical Aspects : Second International Symposium on Binding Proteins (Annals of the New York Academy of Sci). New York Academy of Sciences, 1988.

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Zhongguo ya re dai dong bu qiu ling shan qu shui tu liu shi yu fang zhi (Nan fang shan qu zong he ke xue kao cha zhuan ji). Xin hua shu dian Beijing fa xing suo fa xing, 1989.

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The Knife Of Never Letting Go (Turtleback School & Library Binding Edition) (Chaos Walking). Turtleback Books, 2014.

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Deegan, Patrick. Porphyria. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0179.

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This chapter discusses six diseases caused by inborn errors of metabolism affecting the biosynthesis of haem. Haem is a tetracyclic metal-binding compound involved in oxygen transport (in haemoglobin and myoglobin) and redox reactions (e.g. in the cytochrome P450 system). Each of these conditions is caused by a single gene defect in one of the enzymes involved in the biosynthesis of haem. Inheritance is usually autosomal dominant with incomplete penetrance. The enzyme defect results in disease, not as a result of deficiency of the reaction product, but as a result of accumulation of precursors. Early, soluble precursors, 5-aminolaevulinic acid, and porphobilinogen (not porphyrins as such) are neurotoxic and, when present in great excess, as occurs when flux through the haem synthetic pathway is increased in response to particular medications or hormones, lead to acute neurovisceral crises. Later cyclical precursors (porphyrins) in the pathway are also water soluble and excreted in urine, but are susceptible to activation by electromagnetic radiation in the visible spectrum and are converted to free-radical metabolites that cause pain, inflammation, and tissue damage in the skin. The final haem precursors (also porphyrins) are hydrophobic and excreted in the bile and faeces and are also activated by light to toxic metabolites.
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Srinivas, Krishna Ravi. Intellectual Property Rights and the Politics of Food. Edited by Ronald J. Herring. Oxford University Press, 2014. http://dx.doi.org/10.1093/oxfordhb/9780195397772.013.34.

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The legal status of plant genetic resources has been subject to numerous international agreements and laws over the centuries. The “common heritage of mankind” approach enabled free access but proved unworkable because of conflicts over intellectual property rights. The Convention on Biological Diversity (1992) recognized sovereign rights of nations over genetic resources within their territory. The Trade Related Intellectual Property Rights Agreement under auspices of the World Trade Organization mandated intellectual property protection for plant varieties, but synchronizing such rights has proved problematic. Many developing countries have enacted sui generis regimes to comply with TRIPS requirements. The International Union for the Protection of New Varieties of Plants Convention provides models that have changed over time. With the advent of agricultural biotechnology and availability of intellectual property rights for plant components, patents relating to plant genetic resources have increased. As plant genetic resources are subject to many overlapping treaties, the regime governing them is becoming more complex, resulting in inconsistencies and disputes. While the rights of plant breeders and the private seed industry are well protected in formal agreements, the rights of farmers, who have nurtured diversity in plant genetic resources, developed varieties of crops with different traits, and contributed to exchange and conservation of plant genetic resources, are left to the discretion of nation-states. Farmers’ rights are mentioned in many international legal instruments, but no binding treaty or convention mandates protecting and promoting the rights of working farmers.
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Book chapters on the topic "Ski bindings"

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Posch, Markus, Gerhard Ruedl, Robert Eberle, and Martin Burtscher. "Self-Release of Ski Bindings: A Sex Comparison." In Snow Sports Trauma and Safety, 109–17. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-52755-0_9.

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Lüthi, Anton, Peter Federolf, Mathieu Fauve, and Hansueli Rhyner. "Effect of Bindings and Plates on Ski Mechanical Properties and Carving Performance." In The Engineering of Sport 6, 299–304. New York, NY: Springer New York, 2006. http://dx.doi.org/10.1007/978-0-387-46050-5_53.

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Jeli, Zorana, Boris Kosic, Misa Stojicevic, and Stefan Berdic. "3D Modeling and Analysis of Ski Binding Mechanism." In Advances in Mechanism and Machine Science, 579–87. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-20131-9_58.

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Costa-Scorse, Brenda A., Will G. Hopkins, and Roald Bahr. "Evaluation of Ski-Binding-Boot System Safety Using Torque Testing." In Skiing Trauma and Safety: 20th Volume, 163–70. 100 Barr Harbor Drive, PO Box C700, West Conshohocken, PA 19428-2959: ASTM International, 2014. http://dx.doi.org/10.1520/stp158220130158.

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Cao, Yachao, Akram Elmahdy, Hanjiang Zhu, Xiaoying Hui, and Howard I. Maibach. "Binding Affinity and Decontamination of Dermal Decontamination Gel (DDGel) to Model Chemical Warfare Agent (CWA) Simulants." In Skin Decontamination, 163–81. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-24009-7_10.

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Gaudreault, Manon, Danielle Larouche, Lucie Germain, and Sylvain L. Guérin. "Qualitatively Monitoring Binding and Expression of the Transcription Factor Sp1 as a Useful Tool to Evaluate the Reliability of Primary Cultured Epithelial Stem Cells in Tissue Reconstruction." In Skin Stem Cells, 119–42. Totowa, NJ: Humana Press, 2013. http://dx.doi.org/10.1007/978-1-62703-330-5_11.

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Le-Bel, Gaëtan, Sergio Cortez Ghio, Danielle Larouche, Lucie Germain, and Sylvain L. Guérin. "Qualitatively Monitoring Binding and Expression of the Transcription Factors Sp1 and NFI as a Useful Tool to Evaluate the Quality of Primary Cultured Epithelial Stem Cells in Tissue Reconstruction." In Skin Stem Cells, 43–73. New York, NY: Springer New York, 2018. http://dx.doi.org/10.1007/7651_2018_153.

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Darby, Ian A., and Alexis Desmoulière. "Scar Formation: Cellular Mechanisms." In Textbook on Scar Management, 19–26. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-44766-3_3.

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AbstractFibroblasts are key players in the maintenance of skin homeostasis and in orchestrating physiological tissue repair. Fibroblasts secrete and are embedded in a sophisticated extracellular matrix, and a complex and interactive dialogue exists between fibroblasts and their microenvironment. In addition to the secretion of the extracellular matrix, fibroblasts and myofibroblasts secrete extracellular matrix remodeling enzymes, matrix metalloproteinases and their inhibitors, and tissue inhibitors of metalloproteinases and are thus able to remodel the extracellular matrix. Myofibroblasts and their microenvironment form a network that evolves during tissue repair. This network has reciprocal actions affecting cell differentiation, cell proliferation, cell quiescence, or apoptosis and has actions on growth factor bioavailability by binding, sequestration, and activation. Mechanical forces also play a role in regulating the myofibroblast phenotype as cells are subjected to mechanical stress and mechanical signaling is activated. Innervation is also involved in both skin repair processes and differentiation of myofibroblasts. In pathological situations, for example, in excessive scarring, the dialogue between myofibroblasts and their microenvironment can be altered or disrupted, leading to defects in tissue repair or to pathological scarring, such as that seen in hypertrophic scars. Better understanding of the intimate dialogue between myofibroblasts and their local microenvironment is needed and will be important in aiding the identification of new therapeutic targets and discovery of new drugs to treat or prevent aberrant tissue repair and scarring.
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Eimeleus, K. B. E. E. "Turns on the Move." In Skis in the Art of War, translated by William D. Frank and E. John B. Allen, 73–76. Cornell University Press, 2019. http://dx.doi.org/10.7591/cornell/9781501747403.003.0021.

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This chapter looks at turns on the move with the right or left shoulder aligned with the corresponding ski. It distinguishes three important techniques that have gained currency in the world of sport. One of them pertains only to running skis while the other two require mountain skis with stable bindings. The first is the method for turning in place, used while descending from a mountain or over flat terrain on running skis, or on any skis that lack a stable binding and have a posterior center of balance. The next is the Christiania turn, which is carried out on the inner ski, that is, on the right ski when the turn is done to the right-hand side. Finally, the Telemark turn allows a skier to make a sudden stop as they are descending.
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Eimeleus, K. B. E. E. "Methods of Attaching Skis and Footwear for Skiing1." In Skis in the Art of War, translated by William D. Frank and E. John B. Allen, 38–43. Cornell University Press, 2019. http://dx.doi.org/10.7591/cornell/9781501747403.003.0011.

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This chapter discusses methods for attaching skis. The methods for attaching ski to foot have been through just as many changes as those undergone by skis themselves. Although currently there is no single definitive type of binding that is the unanimous best choice, there are still many quite satisfactory ones. Above all, these methods must meet the following requirements: to give as much solid support for the feet as possible so that the foot is always aligned with the ski; to allow for more movement of the foot along the longitudinal axis of the ski without causing restriction when kneeling; to be put on and taken off quickly and conveniently; to be durable, uncomplicated, and easy to repair; to have just enough evenly distributed pressure without making one's feet cold; to be adjustable for a variety of footwear; and to be moderately priced. Furthermore, the chapter discusses two main groups of bindings: one for running and the other for mountain skis.
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Conference papers on the topic "Ski bindings"

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Bruzzo, John, A. L. Schwab, Aki Mikkola, Antti Valkeapää, Olli Ohtonen, and Vesa Linnamo. "A Simple Mechanical Model for Simulating Cross-Country Skiing Propulsive Force." In ASME 2015 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/detc2015-46454.

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In this paper, a three-dimensional multibody dynamic model of a cross-country skier is developed and presented where a single propulsion phase is modeled to obtain the kinetic parameters involved in the movement. A professional Olympic-level skier performed the skating technique without poles in a ski tunnel under controlled conditions and on an incline plane. Then, with the use of a force acquisition system attached to the ski bindings and a motion capture system set on site, the leg resultant forces and the movement of specific points of the skier’s lower body were acquired. The data obtained from the motion capture system was used as the prescribed kinematic input data in the multibody model and the measured force was used later as a comparison parameter with the results of the simple model. After simulating the technique, the calculated propulsion forces seem to be in agreement with those measured in the field.
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2

Roberts, Jr., Charles C. "Infrared thermal analysis of ski and snowboard binding systems." In Aerospace/Defense Sensing and Controls, edited by Douglas D. Burleigh and Jane W. Maclachlan Spicer. SPIE, 1996. http://dx.doi.org/10.1117/12.235393.

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3

wang, Yifei, Hongbing wang, and Xun xu. "Web Services Scheduling: Binding the Cost with the Time." In 2005 First International Conference on Semantics, Knowledge and Grid. IEEE, 2005. http://dx.doi.org/10.1109/skg.2005.144.

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4

Gao, Kun, Lifeng Xi, and Qin Wang. "Binding Abstract Business Process and Actual Web Services Using Finite State Automata." In 2009 Fifth International Conference on Semantics, Knowledge and Grid. IEEE, 2009. http://dx.doi.org/10.1109/skg.2009.63.

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5

Klein, Kevin M., Gregory T. Ostrowicki, Andrew Gerwitz, and Suresh K. Sitaraman. "Micro and Nano Thin Film Devices as Bio-Assays for Cancer Diagnosis." In ASME 2006 International Mechanical Engineering Congress and Exposition. ASMEDC, 2006. http://dx.doi.org/10.1115/imece2006-15581.

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Micro and nano Au/Cr and Al thin film devices have been fabricated using DC sputtering and e-beam evaporation in combination with e-beam and photo lithography. These devices can be coated with specific reagents to detect and measure the presence of particular antigens and/or complementary DNA sequences with a smaller sample size and at much earlier stages of disease progression compared to current medical diagnostic technologies. Using the device material stack (Au/Cr/Si), we have assessed the binding affinity of Au, Cr, and Si with Protein G, and antibodies for Prostate Specific Antigen (PSA) and Cancer Antigen 125 (CA125), an ovarian cancer-associated antigen. Based on our experiments, we see that the thin gold layer of the Au/Cr/Si samples, provides increased bio-material binding affinity, and the chromium layer has a similar, if not less, binding affinity compared to the silicon chip alone.
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Dumitricaˇ, Traian, Dong-Bo Zhang, and Ming Hua. "Nanomechanics of Silicon Nanowires via Symmetry-Adapted Tight-Binding and Classical Objective Molecular Dynamics." In ASME 2008 International Mechanical Engineering Congress and Exposition. ASMEDC, 2008. http://dx.doi.org/10.1115/imece2008-66802.

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Stability and elastic response of the most promising ground state candidate Si nanowires with less than 10 nm in diameter are comparatively studied with objective molecular dynamics coupled with non-orthogonal tight-binding and classical potential models. The computationally-expensive tight-binding treatment becomes tractable due to the substantial simplifications introduced by the presented symmetry-adapted scheme. Quantitative differences regarding stability with the classical model description are noted. Using a Wulff energy decomposition approach it is revealed that these differences are caused by the inability of the classical potential to accurately describe the interaction of Si atoms on surfaces. Differences between the results of the two atomistic treatments are also noted in the elastic response in elongation.
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7

Castellino, F. J., T. Urano, B. Chibber, and Sator V. de Serrano. "ANIONIC INHIBITION OF PLASMINOGEN ACTIVATION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644374.

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We have found that anions play a significant role in the activation rates of Gluj-plasminogen (GlujPg) by streptokinase (SK) and urokinase (UK), and that these properties of anions can be correlated with their effects on the structure of GlujPg. In the case of activation by SK, a species of activator complex consisting of equimolar SK and GlujPg (SK-Glu]Pg*), that is sensitive to the presence of Cl- and fibrinogen (Fg), exists which decays to another complex of SK and GlujPg (SK-GlujPg'), the activity of which is not influenced by these effector molecules. The overall activation of GlujPg by SK-GlujPg* is inhibited by Cl- and stimulated by Fg. Kinetic studies indicate that Cl- is a mixed type inhibitor of the process, and Fg functions as a mixed type activator.The activation of GlujPg by both high- and low-molecular weight forms of UK is also inhibited by CL-, but is stimulated by e-amino caproic acid (EACA). The inhibition by Cl- does not occur in the presence of concentrations of EACA that saturate its weak binding sites on GlujPg, and the stimulation by EACA is maximally exhibited in the presence of CL-. Based upon structural studies of GlujPg in the presence of a variety of anions, such as Cl-, F-, I-, CNS-, OTs-, IO3 - and OAc-, we find that GlujPg can adopt a conformation (4.8S form) that is optimal to activation by UK, and one that is much less susceptible to such activation (5.8S form). The former occurs in certain salts and appears to correlate inversely with their ability to bind to the protein, or in the presence of any salt, plus saturating levels of EACA. The latter conformation is adopted in direct proportion with the ability of anions to interact with the protein, according to the Hofmeister series.In conclusion, we find that anions serve as inhibitors of activation of GlujPg, effects that are reversed by Fg (for SK) and EACA (for UK). This inhibition, which occurs at physiological concentrations of Cl-, serves to inhibit significantly plasminogen activation in normal circulation. Activation of plasminogen is enhanced upon its binding to surfaces (e.g., fibrin), via its lysine binding sites, an effect which may well contain a contribution from sequestration of Cl- from the protein.
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Kubo, Momoji, Yumiko Sasaki, Keiko Chiba, Pei Qiang, Abdul Rajjak, Hideyuki Tsuboi, Michihisa Koyama, et al. "Large-Scale Quantum Chemical Molecular Dynamics Simulations on the Formation Dynamics of Hydrogen by the Chemical Reactions of Water." In ASME 2005 Summer Heat Transfer Conference collocated with the ASME 2005 Pacific Rim Technical Conference and Exhibition on Integration and Packaging of MEMS, NEMS, and Electronic Systems. ASMEDC, 2005. http://dx.doi.org/10.1115/ht2005-72132.

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We have successfully simulated the chemical reaction dynamics of water molecules on various Si surfaces by using our new tight-binding quantum chemical molecular dynamics method. The formation dynamics of hydrogen molecules from water molecules on Si nano-particle was observed at 300 K. Especially, we found that the surface termination of Si nano-particle strongly influences the chemical reactions of water molecules and the non-terminated Si surface is the active site for the hydrogen generation. Moreover, we suggest that nano-space of the SiO2/Si interface is more active site for the hydrogen generation.
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9

Shaw, S. S. S., and K. S. S. Sorbie. "Structure, Stoichiometry, and Modelling of Mixed Calcium Magnesium Phosphonate Scale Inhibitor Complexes for Application in Precipitation Squeeze Processes." In SPE International Oilfield Scale Conference and Exhibition. SPE, 2014. http://dx.doi.org/10.2118/spe-169751-ms.

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Abstract In this paper, the properties of precipitated “mixed” calcium and magnesium phosphonate scale inhibitor (SI) complexes formed by 9 common phosphonate species are investigated. These complexes are of the form SI_ CaNl _MgN2 where the stoichiometry (Ca2+/SI and Mg2+/SI molar ratios, i.e. N1 and N2) in various precipitates are established experimentally, and the effect of solution pH on the stoichiometry is determined. Static precipitation tests were performed varying the amounts of Ca2+ and Mg2+ present in the system (at a constant ionic strength), at test temperatures ranging from 20°C to 95°C, at a fixed [SI] = 2, 000ppm. The stoichiometries of the solid precipitates were determined by assaying for Ca2+, Mg2+, and P in the supernatant liquid, under each test condition, by ICP spectroscopy. It is shown experimentally that, for all 9 phosphonates tested, these stoichiometries (i.e. N1 and N2 in SI_ CaN1 _MgN2) depend on (i) the nature of the SI (i.e. M2+ binding sites per molecule); (ii) solution pH, which affects the speciation of the SI; (iii) the relative magnitude of the SI binding constants to Ca2+ and Mg2+ at the test pH (Kb1 and Kb2, respectively); and (iv) the solution molar ratio of Mg2+/Ca2+. It is found that, as pH increases, the combined molar ratio of Ca2+ and Mg2+ to SI, i.e. Nt = N1 + N2 in the complex, increases up to a theoretical maximum, Nt,max, depending on the chemical structure of the phosphonate (corroborating earlier work, SPE 155114, SPE 164051). In addition, the precipitation behaviour of the various compounds is modelled theoretically by developing and solving a set of simplified equilibrium equations. Very good agreement is seen between the modelling and experimental results. Such models can be used directly in the simulation of field phosphonate precipitation squeeze treatments in order to design and optimize squeeze lifetimes.
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10

Tian, Qingguo, Xiaojie Li, and Baozhen Ge. "Implementation of digital human modeling and skin deformation based on flexible model and multi-joints-binding method." In Sixth International Symposium on Multispectral Image Processing and Pattern Recognition, edited by Mingyue Ding, Bir Bhanu, Friedrich M. Wahl, and Jonathan Roberts. SPIE, 2009. http://dx.doi.org/10.1117/12.832765.

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