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Dissertations / Theses on the topic 'Skin diseases - genetics - South Africa'

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Published: 4 June 2021

Last updated: 4 February 2022

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1

Winship, Ingrid M. "Epidermolysis bullosa in South Africa." Doctoral thesis, University of Cape Town, 1986. http://hdl.handle.net/11427/25674.

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2

Agenbag, Gloudi. "Molecular genetic analysis of familial breast cancer in South Africa." Thesis, Link to the online version, 2005. http://hdl.handle.net/10019/953.

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3

De, Koker Wenhelene Crystal. "Molecular characterization of grapevine virus E in South Africa." Thesis, Stellenbosch : Stellenbosch University, 2012. http://hdl.handle.net/10019.1/71709.

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Thesis (MSc)--Stellenbosch University, 2012.<br>ENGLISH ABSTRACT: Grapevine virus E (GVE) is a newly identified virus that has been detected in an established vineyard in South Africa. This virus is a member of the genus Vitivirus, family Flexiviridae. Members of this genus are known to infecte grapevine and are associated with various disease complexes, such as the Rugose wood complex (RWC) and Shiraz disease (SD). However, the role and impact of GVE in South African vineyards are still unknown. It is important to study these viruses to determine how they infect and the possible impact they m

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Oyekunle, Olubunmi Simeon. "Potential anti-melanogenic effects of selected South African plants on b16 melanoma cells." University of the Western Cape, 2019. http://hdl.handle.net/11394/7002.

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Philosophiae Doctor - PhD<br>Dyspigmentation is one of the commonest dermatological presenting complaints from patients, particularly hyperpigmentation. Hyperpigmentation can cause dangerous psychological and emotional impact on self-perception and health quality of lives of people affected. However, of all the diseases encountered globally, epidemiological data has shown that skin diseases account for almost 34% of all the diseases and these dermatological disorders have gotten worse over time. The gold standard for treatment of hyperpigmentation is hydroquinone. Despite its efficacy, hydroqu

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5

Weideman, Heinrich. "A genetic analysis of the occurrence of pulmonary haemorrhage in racing thoroughbreds in Southern Africa." Thesis, Stellenbosch : Stellenbosch University, 2004. http://hdl.handle.net/10019.1/49819.

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Dissertation (PhD(Agric))--University of Stellenbosch, 2004.<br>ENGLISH ABSTRACT: This study was carried out to investigate whether environmental and/or genetic factors had an effect on the incidence of epistaxis related to exercise-induced pulmonary haemorrhage among racehorses in Southern Africa. A further aim was to estimate the heritability of liability to epistaxis in the Southern African Thoroughbred population. For the purpose of the environmental study, the data covering the period 1986-2001 and involving a total of778 532-race runs, were analysed. This included the following ra

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6

Nyanhongo, Nhamo. "Field trial to evaluate the brucellin skin test in cattle in the Mpumalanga Province, South Africa." Diss., University of Pretoria, 2012. http://hdl.handle.net/2263/33370.

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Brucellosis is a disease of socio-economic and zoonotic importance worldwide. In animals it is associated with the ingestion of feed that is contaminated with cyetic material from aborting herd-mates, while in humans it is associated with the consumption of unpasteurised milk and dairy products from infected animals. It may also be acquired from contact with infected material of animal origin by farmers, veterinarians, and abattoir and laboratory workers. Brucellosis was first reported in South Africa in the late nineteenth century. It is still present in the country today, with reporte

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7

Bester, Rachelle. "Sequencing and detection of a new strain of grapevine leafroll-associated virus 3 in South Africa." Thesis, Stellenbosch : Stellenbosch University, 2012. http://hdl.handle.net/10019.1/71743.

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Thesis (MSc)--Stellenbosch University, 2012.<br>ENGLISH ABSTRACT: Grapevine leafroll-associated virus 3 (GLRaV-3) is the type member of the genus Ampelovirus in the family Closteroviridae and is considered to be the main contributing agent of grapevine leafroll disease (GLD) worldwide. A metagenomic sequencing study of a grapevine leafroll-diseased vineyard led to the discovery of a new variant of GLRaV-3 in South Africa. This new variant was most related to a New Zealand isolate, NZ-1. In this study, we sequenced two isolates, GH11 and GH30, of the new variant group of GLRaV-3. These isolates

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8

Lynch, Alisson. "Comparisons of levels of genetic diversity among Streptomyces scabies isolates of South Africa using various DNA techniques." Thesis, Stellenbosch : Stellenbosch University, 2000. http://hdl.handle.net/10019.1/51658.

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Thesis (MSc)--University of Stellenbosch, 2000.<br>ENGLISH ABSTRACT: Streptomyces spp. are responsible for a large proportion of the world-wide quality deterioration of potatoes causing a potato tuber disease called cornmon scab. Determining the genetic diversity of the Streptomyces spp., especially the main pathogen, S. scabies, has been a prerequisite for the ultimate control of common scab. Techniques responsible for the classification and determination of genetic diversity have improved with advances in DNA technology. Analysis of South African (S.A.) S. scabies isolates has been foc

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9

Carstens, Roleen. "The incidence and distribution of grapevine yellows disease in South African vineyards." Thesis, Stellenbosch : Stellenbosch University, 2014. http://hdl.handle.net/10019.1/86683.

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Thesis (MSc)--Stellenbosch University, 2014.<br>ENGLISH ABSTRACT: South Africa is ranked eighth in the world as far as international wine production is concerned and in terms of area under bearing vines South Africa is ranked 12th. In 2011 the wine industry contributed R4 204.4 million to the South African economy in state revenue from wine products. The importance of viticulture to the economy of South Africa forces the industry to limit the effect of all disease causing pathogens in order to keep their competitive edge. Aster yellows (AY) phytoplasma 16SrI-B subgroup was reported for th

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10

Mahachi, Josia. "Medicinal properties of some plants used for the treatment of skin disorders in the O. R. Tambo and Amathole Municipalities of the Eastern Cape Province, South Africa." Thesis, Walter Sisulu University, 2013. http://hdl.handle.net/11260/101.

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The use of medicinal plants for treatment of skin infections and improvement of skin tone was assessed. The study covered Amathole and OR Tambo municipalities of the Eastern Cape Province of South Africa. The study sought to identify and document some medicinal plants which are used by the indigenous people on the skin, evaluate some biological properties which attribute to their use for therapeutic use. This report provides ethnobotanical data on some plant which were identified. Six medicinal plants (Kniphofia drepanophylla, Gnidia capitata, Hypoxis hemerocallidea, Syzgium cordatum, Macarang

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11

Le, Maitre Nicholas Carlyle. "Molecular genetic study of wheat rusts affecting cereal production in the Western Cape." Thesis, Stellenbosch : University of Stellenbosch, 2010. http://hdl.handle.net/10019.1/3183.

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Thesis (MSc (Genetics))--University of Stellenbosch, 2010.<br>ENGLISH ABSTRACT: Microsatellites were used to differentiate Leaf (Puccinia triticina Eriks.) and Yellow rust (Puccinia striiformis Westend. f. sp. tritici Eriks.) pathotypes. There was sufficient diversity in the Leaf rust microsatellite markers to differentiate the pathotypes and create a phylogenetic tree of Leaf rust. Three of the microsatellite markers were sufficient to differentiate all the Leaf rust pathotypes. Sufficient diversity in the Yellow rust microsatellite markers was also observed which made it possible to differen

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12

McGregor, Nathaniel Wade. "Characterization of the promoter region of the HAMP gene implicated in iron metabolism and its possible association with Oesophageal cancer in the black South African population." Thesis, Stellenbosch : University of Stellenbosch, 2009. http://hdl.handle.net/10019.1/1648.

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Thesis (MSc (Genetics))--University of Stellenbosch, 2009.<br>ENGLISH ABSTRACT: Oesophageal cancer (OC) is the sixth leading cause of cancer related deaths in the world with approximately 300 000 new cases reported each year. OC may be characterized into two forms with 90% of cases presenting as squamous-cell carcinoma (SCC) and the remaining 10% as adenocarcinoma (ADC). Several factors have been attributed to the development of OC, including oesphageal injury and/or irritation, chronic inflammation and excess iron associated with enhanced tumour growth. The HAMP gene codes for a 25 amino-aci

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13

Liebenberg, Annerie. "The development of an enzyme linked immunosorbent assay for the detection of the South African strain(s) of grapevine fanleaf nepovirus." Thesis, Link to the online version, 2008. http://hdl.handle.net/10019/1909.

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14

Timm, Alicia (Alicia Eva). "Genetic diversity of root-infesting woolly apple aphid Eriosoma lanigerum (Hausmann) (Hemiptera: Aphididae) populations in the Western Cape." Thesis, Stellenbosch : Stellenbosch University, 2003. http://hdl.handle.net/10019.1/53436.

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Thesis (MScAgric)--University of Stellenbosch, 2003.<br>ENGLISH ABSTRACT: Characterizing the genetic structure of a pest population can provide an understanding of the factors influencing its evolution and assist in its ultimate control. The aim of the present study was to characterize the genetic structure of woolly apple aphid Eriosoma lanigerum (Hausmann) populations in the Western Cape Province in South Africa. Since this economically important apple pest has not previously been characterized at molecular level, it was necessary to evaluate methods for determining the genetic structur

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15

Madzimure, James. "Climate change adaptation and economic valuation of local pig genetic resources in communal production systems of South Africa." Thesis, University of Fort Hare, 2011. http://hdl.handle.net/10353/427.

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The broad objective of the study was to determine the economic value of local pigs in marketand subsistence-oriented production systems in communal areas of Southern Africa. Data were collected from 288 households to investigate farmer perceptions, effects on pig production and handling of disease outbreaks such as classical swine fever (CSF) in market- and subsistenceoriented production systems. The utilisation of local pigs in these market- and subsistenceoriented production systems in improving people‟s welfare was evaluated. Climate change was identified by farmers in these production syst

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Timm, Alicia Eva. "Morphological and molecular studies of tortricid moths of economic importance to the South African fruit industry." Thesis, Link to the online version, 2005. http://hdl.handle.net/10019/1347.

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17

Noach, Liesl Christine. "The molecular characterization of South African isolates of Grapevine Rupestris Stem Pitting-associated virus (GRSPaV)." Thesis, Stellenbosch : University of Stellenbosch, 2010. http://hdl.handle.net/10019.1/5252.

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Thesis (MSc (Genetics))--University of Stellenbosch, 2010.<br>Includes bibliography.<br>ENGLISH ABSTRACT: The first aim of this study was to reliably and rapidly detect Grapevine rupestris stem pittingassociated virus (GRSPaV) in grapevine. This was achieved by screening 94 grapevines using crude plant extracts in both quantitative and conventional reverse transcription polymerase chain reaction (RT-PCR). The second aim was to establish a technique capable of differentiating GRSPaV sequence variants. The application of this technique is for the largescale screening of diseased vines to as

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18

Coetzee, Beatrix. "A metagenomic approach using next-generation sequencing for viral profiling of a vineyard and genetic characterization of grapevine virus E." Thesis, Stellenbosch : University of Stellenbosch, 2010. http://hdl.handle.net/10019.1/5186.

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Thesis (MSc (Genetics))--University of Stellenbosch, 2010.<br>Includes bibliography.<br>Title page: Dept. of Genetics, Faculty of Science<br>ENGLISH ABSTRACT: Next-generation sequencing technologies are increasingly used in metagenomic studies, largely due to the high sequence data throughput capacity and unbiased approach in determining the genetic composition of an unknown environmental sample. This study investigated the applicability of the Illumina next-generation sequencing platform for metagenomic sequencing of grapevine viruses to provide the first complete viral profile, or virome

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19

Wessels, Andries Bernardus. "Genetic characterization and fungicide resistance profiles of Botrytis cinerea in rooibos nurseries and pear orchards in the Western Cape of South Africa." Thesis, Stellenbosch : Stellenbosch University, 2012. http://hdl.handle.net/10019.1/20070.

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Thesis (MScAgric)--Stellenbosch University, 2012.<br>ENGLISH ABSTRACT: Botrytis cinerea Pers. Fr. [teleomorph Botryotinia fuckeliana (de Bary) Whetzel] causes serious losses of over 200 crops worldwide, including rooibos seedlings and pears. This pathogen is characterized by morphological, physiological and genetic diversity. The genetic diversity and population structure have not been investigated for B. cinerea populations in South Africa. Botrytis cinerea collected from rooibos seedlings and in pear orchards in the Western Cape of South Africa were investigated in the present study. T

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20

Anguria, Peter. "Determinants of pterygium occurrence and recurrence in a rural African population." Thesis, 2015. http://hdl.handle.net/10539/18673.

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A Thesis submitted to the Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, in fulfilment of the requirements for the degree of Doctor of Philosophy<br>Pterygium, a wing-shaped fibrovascular growth of the conjunctiva onto the cornea, can impair vision and be cosmetically unacceptable. Its frequency varies in Africa and postsurgical recurrence in blacks may be high. Determinants of pterygium occurrence and recurrence in rural Africans are not known. This study aimed to establish the determinants of pterygium occurrence and recurrence in rural blacks. The case co

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21

Hlela, Carol. "Human T cell lymphotropic virus 1 associated infective dermatitis in KwaZulu-Natal, South Africa." Thesis, 2008. http://hdl.handle.net/10413/2530.

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Background Human T cell Lymphotropic Virus Type I (HTLV-I) associated infective dermatitis, first described by Sweet in Jamaican children, is a pattern of eczema characterized by exudation, crusting around the nostrils, ears and scalp with eventual appearance of a generalized fine papular rash. More recently LeGranade and co-workers have proposed major and minor criteria in establishing the diagnosis of HTLV-I associated infective dermatitis (HAID). HTLV-I has been aetiologically linked to Adult T cell leukaemia/lymphoma (ATLL) and tropical spastic paraparesis (TSP). HAID is not only a m

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22

Mhora, Terence Tariro. "Genomics of quantitative resistance to brown rust (Puccinia melanocephala) in a sugarcane breeding population." Thesis, 2012. http://hdl.handle.net/10413/10036.

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The Sugarcane Industry contributes approximately 400 000 jobs and ZAR 8 billion annually to South Africa’s economy. Due to climate change and the subsequent threat posed by disease, these figures have been on the decline. Brown rust, a contributor to this decline is caused by the basidiomycete Puccinia melanocephala Syd. and P. Syd., which previously resulted in 50% yield losses in susceptible varieties. This highlighted the need for improved screening and breeding techniques which will result in the replacement of susceptible varieties. The objectives of this study were to: a) Adopt and optim

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23

Gounden, Nirmala. "Apolipoprotein E allele distribution in a South African Indian female population : effect on the lipid profile." Thesis, 1993. http://hdl.handle.net/10413/7453.

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Genetic polymorphism of apolipoprotein (apo) E has been shown to account for a significant amount of variance in plasma lipid and lipoprotein levels, thereby contributing to the incidence of cardiovascular disease across populations. In this cross-sectional study apo E genotypes were determined in a sample of 173 healthy, middle-aged Indian women using a restriction isotyping method, in which DNA was amplified by PCR and the Cfol restricted DNA fragments were separated on a polyacrylamide gel, allowing unambiguous typing of the common apo E genotypes. Considering the three common alleles, e2,

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24

Allie, Farhahna. "Gene expression studies towards the elucidation of host responses to South African cassava mosaic virus." Thesis, 2014.

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A thesis submitted to the Faculty of Science, University of the Witwatersrand, Johannesburg, in fulfilment of the requirements for the degree of Doctor of Philosophy. Johannesburg, 2013.<br>Unable to load abstract.

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25

Ibaba, Jacques Davy. "Characterization of potato virus Y (PVY) isolates infecting solanaceous vegetables in KwaZulu-Natal (KZN), Republic of South Africa (RSA)." Thesis, 2009. http://hdl.handle.net/10413/613.

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Potato virus Y (PVY) is an economically important virus worldwide. In South Africa, PVY has been shown to be a major limiting factor in the production of important solanaceous crops, including potato (Solanum tuberosum L.), pepper (Capsicum annuum L.), tomato (Lycopersicon esculentum Mill.) and tobacco (Nicotiana spp). The variability that PVY displays, wherever the virus occurs, merits the study of the isolates occurring in KwaZulu-Natal (KZN) in the Republic of South Africa (RSA). This characterization will provide a clear understanding of strains/isolates from local vegetables and how they

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26

Mafokwane, Tshepo Malesela. "Effects of host genetic polymorphisms on the occurrence of schistosomiasis and chlamydia in Limpopo Province." Diss., 2016. http://hdl.handle.net/11602/827.

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27

Sikhakhane, Thandeka Nokuthula. "Genetics of Russian wheat aphid (Diuraphis noxia) resistance in bread wheat (Triticum aestivum L.) accession CItr 2401." Diss., 2017. http://hdl.handle.net/10500/22961.

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The Russian wheat aphid (RWA) (Diuraphis noxia Kurdjumov) is one of the important insect pests of wheat (Triticum aestivum L.), barley (Hordeum vulgare L.) and other grasses. To date, there are four RWA biotypes identified in South Africa. The virulent biotypes emerged, partly due to climate change and new genetic variations within populations of RWA; hence there is a need to improve host-plant resistance, as an effective control measure. Bread wheat (Triticum aestivum L.) accession Cereal Introduction (CItr) 2401 is known to be resistant to all RWA biotypes worldwide. The goal of this study w

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Masemola, Puseletso Maselepe. "Genomic characterisation and antimicrobial resistance profiles of Listeria monocytogenes isolated from pig farms." Diss., 2021. http://hdl.handle.net/10500/27687.

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Listeria monocytogenes is a zoonotic foodborne pathogen, transmissible from the natural agricultural environment to animals and humans. In recent years, the pig production industry has experienced a series of monetary losses as a result of the L. monocytogenes outbreak which threatened the economy of South Africa. This outbreak also had a detrimental effect on the health system of the country. In South Africa however, there is limited information regarding the genomic diversity of L. monocytogenes. Therefore, an overview of the genomic diversity of L. monocytogenes strains circulating at

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