Relevant bibliographies by topics / Skin-grafting

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Skin-grafting'

Author: Grafiati
Published: 4 June 2021
Last updated: 30 July 2024

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Journal articles on the topic "Skin-grafting"

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Mendez-Eastman, Susan K. "Skin Grafting." Plastic Surgical Nursing 21, no. 1 (2001): 49–51. http://dx.doi.org/10.1097/00006527-200121010-00012.

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Fortier, Jillian L., and Charles L. Castiglione. "Skin Grafting." Techniques in Orthopaedics 27, no. 4 (December 2012): 244–49. http://dx.doi.org/10.1097/bto.0b013e31827849d1.

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Valencia, Isabel C., Anna F. Falabella, and William H. Eaglstein. "SKIN GRAFTING." Dermatologic Clinics 18, no. 3 (July 2000): 521–32. http://dx.doi.org/10.1016/s0733-8635(05)70199-6.

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Ratner, Désirée. "SKIN GRAFTING." Dermatologic Clinics 16, no. 1 (January 1998): 75–90. http://dx.doi.org/10.1016/s0733-8635(05)70488-5.

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Timmons, M. J. "Skin grafting." British Journal of Plastic Surgery 44, no. 4 (1991): 319. http://dx.doi.org/10.1016/0007-1226(91)90085-x.

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Ratner, Désirée. "Skin grafting." Seminars in Cutaneous Medicine and Surgery 22, no. 4 (December 2003): 295–305. http://dx.doi.org/10.1016/s1085-5629(03)00079-8.

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Donato, Michael C., David C. Novicki, and Peter A. Blume. "Skin Grafting." Clinics in Podiatric Medicine and Surgery 17, no. 4 (October 2000): 561–98. http://dx.doi.org/10.1016/s0891-8422(23)01151-5.

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Abenavoli, Fabio Massimo, and Roberto Corelli. "ABOUT SKIN GRAFTING." Plastic and Reconstructive Surgery 111, no. 4 (April 2003): 1563–64. http://dx.doi.org/10.1097/00006534-200304010-00041.

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Murison, Maxwell. "Split skin grafting." Practice Nursing 7, no. 7 (April 16, 1996): 33–37. http://dx.doi.org/10.12968/pnur.1996.7.7.33.

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Pope, Eric R. "Mesh Skin Grafting." Veterinary Clinics of North America: Small Animal Practice 20, no. 1 (January 1990): 177–87. http://dx.doi.org/10.1016/s0195-5616(90)50009-1.

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Dissertations / Theses on the topic "Skin-grafting"

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Varley, Claire Alison. "T-cells and transplantation tolerance in thymectomised Xenopus implanted with foreign thymus." Thesis, Durham University, 1990. http://etheses.dur.ac.uk/5962/.

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This thesis investigates the expression of a T-cell differentiation antigen, (XTLA- 1), in various strains and species of Xenopus, and demonstrates the effect of early-thymectomy, (by microcautery), on XTLA-1 expression. It further examines restoration of the T-cell dependent immune system, (particularly with respect to transplantation responses), and the extent to which tolerance to donor antigens is achieved by implantation of xenogeneic, as well as allogeneic, thymi into early- thymectomised Xenopus larvae. The means by which transplantation tolerance is maintained in intact, control Xenopus, following perimetamorphic skin grafting, is also addressed. Initial work, reported in Chapter 2, showed that XTLA-1 is expressed by the majority of thymocytes and by a proportion of splenocytes from all X.laevis, X.borealis, and hybrid clonal Xenopus,(X.laevis x X.gilli and hybrid X.laevis x X.muelleri),examined. X.tropicalis lymphocytes, however, do not express XTLA- 1. Early-thymectomy by microcautery effectively removes T-cells, as detected by XTLA-1 expression. In Chapter 3, normal adult and larval tissue distribution of XTLA-1 positive cells is described, and the XTLA-1 and X.borealis,(quinacrine fluorescence), markers are employed to demonstrate the differentiation of T-cells derived from early- thymectomised hosts within xenogeneic, (X.tropicalis), thymus implants. The effects of implantation of allogeneic and xenogeneic larval thymi into early-thymectomised hosts, in terms of T-cell responses and of induction of tolerance to thymus donor antigens, is explored in Chapter 4; X.borealis xenogeneic thymus implants are apparently as effective in these regards as are allogeneic implants, but X.tropicalis xenogeneic thymus implants do not fully restore thymus-dependent immune responses. Preliminary investigations of skin graft rejection, mixed leukocyte culture and T-cell mitogen responses of X.tropicalis, in comparison to those of other Xenopus species, are reported in Chapter 5; the results of these experiments raise the possibility that X.tropicalis splenocytes are less responsive, in mixed leukocyte culture, to xenogeneic stimulators than are splenocytes of other Xenopus species. In Chapter 6, histological examination of skin grafts, accepted by virtue of the tolerance induced by prior implantation of a thymus gland from the skin graft donor into the early-thymectomised hosts, reveals some rapid alteration in the composition of these skin grafts; infiltration of the tolerated skin grafts by host-derived lymphocytes suggests that tolerance induced by thymus implantation does not abrogate recognition of thymus donor antigens. Finally, also in Chapter 6, tolerance induced in control, intact Xenopus by perimetamorphic skin grafting is shown to be susceptible to cyclophosphamide injection, suggesting that the maintenance of this tolerance is mediated by suppressor cells.
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Jankūnas, Vytautas. "Odos persodinimo operacijos veiksmingumas gydant lėtines venines kojų opas." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2005. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2005~D_20050630_213621-87507.

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Abbreviations ADP – autodermoplastics. CUL – chronic ulcers of legs. CVUL – chronic venous ulcers of legs. DGP – a doctor of general practice. KMU – Kaunas Medicine University. KMUH –Kaunas Medicine University Hospital. CSVD – Clinic of Skin and Venereal diseases. 1. Introduction The pathology of chronic ulcers of legs is quite often and it makes a huge influence on the daily life of a patient. According to the literature, ulcers open to 1,5 from 1000 people who are under the age of 65, and if we take into account healed up ulcers of legs, there are 36 people from 1000 to whom ulcers of legs have ever been opened. The reason of ulcers up to 80% of all cases is chronic insufficiency of veins. In Lithuania there are about 150 000 patients suffering from the chronic insufficiency of leg vein blood circulation, and about 30 000 of which are venous ulcers of legs. As in Lithuania in some of the medical institutions the treatment and the prophylaxis of chronic venous blood circulation and ulcers is insufficient, the above mentioned numbers of patients may be even higher. All the authors have noted that the oftenest reason of CUL is the insufficiency of venous blood circulation. In this case, CUL open due to the increased pressure in leg veins. The main reason for that is the insufficiency of surface and deep veins and the perforating vein valves. The good functioning of mentioned veins and their valves is necessary so that the blood could come back to the heart during each... [to full text]
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Tay, Sock P. "New strategies towards the next generation of skin-friendly artificial turf surfaces." Thesis, Loughborough University, 2016. https://dspace.lboro.ac.uk/2134/22979.

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The issue of skin friction related injuries has been one of the problems challenging the artificial sports turf industry. It has been identified by users as a major factor impeding acceptance of artificial turf at the professional level. However, information explaining the mechanisms for skin-turf abrasion is limited and little progress has been made, it appears, to derive an appropriate testing method for product approval or in evidence of improvement of the skin-friendliness of these products in sport surface surfaces. This research project focused on exploring the potential for improving the skin-friendliness of artificial turfs through a multi-faceted approach: identifying the contribution of the abrasive-components in modern artificial turf surfaces through mechanical testing; while critically evaluating currently available skin friction standards , evaluating strategies for polymer material modifications to reduce the skin-surface friction; and the designing of an appropriate bench-top set-up for the lab-based assessment of material skin-friendliness. The lack of understanding of skin-turf interaction was addressed by identifying the turf-component that has the greatest influence on the skin-turf friction with the mechanical device used in the current industry standard. The skin -turf frictional profiles of a series of third generation (3G) turf surfaces were examined, in combination with independent measurements of the silicone skin surface roughness pre- and post-friction testing. Results indicated that turf carpets without any infill material exhibited the highest frictional values while surfaces completely filled with either sand or rubber displayed similarly low frictional values, independent of infill type. Morphological measurements also showed the largest decrease in surface roughness for skin samples tested on carpet-only surfaces, indicating a smoothening effect via abrasion. This abrading effect is alleviated with the addition of infill to the surface, with fully-filled surfaces having the least damage to the skin s. This unprecedented study suggests that the carpet may have the largest influence on the overall frictional behaviour of an artificial turf surface narrowing down the turf component to be targeted when applying product improvements to address skin-friendly properties. The strategy of material surface modification was then employed, to study the effect of polyzwitterionic brushes on improving the skin-friendliness of the identified polypropylene substrate. To address the intended application for artificial turfs, a bench-top test was developed to investigate the frictional properties of the hydrated samples outside of commonly used aqueous environments, where an excess of lubricating water molecules is absent. Photo-grafted poly(sulfobetaine methacrylate) (pSBMA) brushes of various irradiation durations were prepared and the improvement in frictional properties was studied. Frictional measurements using silicone skin tips, under both dry and hydrated surface conditions, showed that the applied modification was capable of forming a stable lubrication layer in the absence of excess water, significantly reducing the coefficient of friction by up to 78.8 %. The pSBMA brushes also provided the additional advantage of antifouling exhibiting resistance towards pathogenic Staphylococcus aureus with almost zero surface colonization for well-grafted samples. The low skin -sample friction under ambient conditions and desirable fouling-resistance highlights the potential of pSBMA brushes as a modification strategy for achieving skin-friendly surfaces targeted at reducing the risk of skin abrasions. The tribological implications of counter-surface selection were investigated. Frictional assessments of the pSBMA-modified samples were carried out using standard steel tribo-tips, in addition to the skin tips used. Measurements with the skin tips showed that the hydrated pSBMA brushes were successful in reducing initial skin -sample friction though the effect diminishes with extended testing, attributed to the drying of the interfacial water. The standard steel tribo-tips were unable to reciprocate these results, returning consistently low frictional values regardless of extent of surface modification or hydration. These observations draw attention to the importance of counter-surface selection in frictional assessments, highlighting how appropriate test materials can identify characteristic surface properties while providing an interaction that simulates that of the intended application. The simple experimental set-up used may potentially be enhanced as an intermediate product qualification method in the manufacturing of skin-friendly artificial turf yarns.
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Warde, David M. "The influence of the hair follicle cycle on wound healing and hypodermal adipose tissue, and its implications for skin grafting." Thesis, University of Manchester, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.572436.

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Hecker, Norman Philipp [Verfasser], and Bernd Dieter [Akademischer Betreuer] Domres. "Intermingled skin grafting – die „chinesische Methode“ : eine Behandlungsmethode Schwerstbrandverletzter im Individualfall und unter Katastrophenbedingungen / Norman Philipp Hecker ; Betreuer: Bernd Dieter Domres." Tübingen : Universitätsbibliothek Tübingen, 2016. http://d-nb.info/1163665231/34.

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Souto, Luis Ricardo Martinhão. "Modelo de pele humana (derme + epiderme) reconstruida in vitro." [s.n.], 2005. http://repositorio.unicamp.br/jspui/handle/REPOSIP/313309.

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Orientador: Maria Beatriz Puzzi, Maria Helena Stangler Kraemer
Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas
Made available in DSpace on 2018-08-04T03:54:34Z (GMT). No. of bitstreams: 1 Souto_LuisRicardoMartinhao_M.pdf: 2402921 bytes, checksum: a79b6ae181ce1b24d01ec608815d8bf7 (MD5) Previous issue date: 2005
Resumo: A obtenção de uma pele humana que apresente derme e epiderme, reconstruída a partir de células isoladas de pacientes, possibilita a realização de enxertos autólogos de pele reconstruída em laboratório (in vitro) em pacientes com áreas doadoras escassas além de permitir ensaios com substâncias químicas e drogas in vitro e não mais in vivo. A partir da cultura de fibroblastos humanos, é possível obter um número suficiente de células que podem ser injetadas em uma matriz de colágeno bovino tipo I que, mantida imersa em meio de cultura, específico para fibroblastos, permite a formação de uma derme humana reconstruída in vitro. Sobre essa derme, através de cultura de queratinócitos e melanócitos humanos, forma-se uma epiderme diferenciada levando à formação de uma pele humana reconstruída in vitro, constituída de derme e epiderme associadas. Essa pele humana formada é, histologicamente, semelhante à pele humana in vivo. Na derme, identifica-se o tecido colágeno, com suas células, e a matriz extracelular organizados paralelamente à epiderme. Esta se desenvolve em várias camadas. Não há distinção entre derme e epiderme no experimento controle, onde não foi utilizado o colágeno bovino tipo I
Abstract: The technique to obtain human skin presenting dermis and epidermis reconstructed from cells isolated from patients allows the performance of autologous grafts of skin reconstructed in laboratory (in vitro) on patients with scarce donor sites, in addition to permitting trials with chemical substances and drugs no more in vivo, but in vitro. It is possible to obtain a sufficient number of cells from human fibroblast culture that can be injected in bovine collagen type I matrix and kept submerged in a specific culture medium for fibroblasts. This will permit the formation of human dermis reconstructed in vitro. On this dermis, through culture of human keratinocytes and melanocytes, a differentiated epidermis is formed, leading to the creation of human skin reconstructed in vitro, composed of associated dermis and epidermis. This human skin is histologically formed in the same way as human skin in vivo. Collagen tissue can be identified in the dermis, with its cells and extracellular matrix organized in parallel to the epidermis, which is developed in several layers
Mestrado
Patologia Clinica
Mestre em Ciências Médicas
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Lindberg, Carin Susanne Margareta. "Real & Imagined Foundational Narratives in the Context of Colonialism - Resurfacing Through A Phenomenological Separation of Body & Skin." Thesis, Malmö universitet, Fakulteten för lärande och samhälle (LS), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-27596.

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Denna artikel försöker utveckla Sara Ahmeds forskning om fenomenologi för att inkludera en fenomenologisk separation av kropp och hud för att förstå pågående kolonialism i Australien/Country. Det hävdas att kolonisatörens misstro till den koloniserade personens kunskapsproduktionen har lett till att kolonisatören har skapat en imaginär grundläggande nationsberättelse. Det hävdas vidare att kolonialismen kommer att fortsätta fram tills att kolonisatören kan skapa en verklig grundläggande nationsberättelse och i sin tur kan detta inte ske förrän den koloniserade personens kunskapsproduktion erkänns.
This paper is attempting to develop Sara Ahmed’s research on phenomenology to include a phenomenological separation of body and skin in order to understand ongoing colonialism in Australia/Country. It is argued that coloniser rejection of colonisee knowledge production has led to a coloniser imaginary foundational narrative. Further, it is argued, colonialism cannot come to an end until the coloniser can create a real foundational narrative and, in turn, this cannot occur until colonisee knowledge production is acknowledged.
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Talbert, Robert John. "Photoacoustic discrimination of viable and thermally coagulated blood for burn injury imaging." Diss., Columbia, Mo. : University of Missouri-Columbia, 2007. http://hdl.handle.net/10355/5081.

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Thesis (M.S.)--University of Missouri-Columbia, 2007.
The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from title screen of research.pdf file (viewed on January 11, 2008) Includes bibliographical references.
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Bonfá, Aline Fabrini. "Efeito do gel de plasma rico em plaquetas na cicatrização de enxertos cutâneos em equinos = Effect of platelet-rich plasma on the repair of skin grafting in horses / Aline Fabrini Bonfá ; orientadora, Antonia Maria Binder do Prado." reponame:Biblioteca Digital de Teses e Dissertações da PUC_PR, 2011. http://www.biblioteca.pucpr.br/tede/tde_busca/arquivo.php?codArquivo=2206.

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Dissertação (mestrado) - Pontifícia Universidade Católica do Paraná, São José dos Pinhais, 2011
Bibliografia: f. 44-48
O gel de plasma rico em plaquetas (PRP) é uma concentração autóloga de plaquetas em um pequeno volume de plasma com potencial de melhorar a integração dos enxertos. O objetivo deste estudo foi avaliar os efeitos do uso do gel de plasma rico em plaquetas s.
The gel of platelet-rich plasma (PRP) is an autologous concentration of platelets in a small volume of plasma with the potential to improve the integration of the grafts. The aim of this study was to evaluate the effects of using gel platelet-rich plasma
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Gillies, Peter John. "Modulation of dermal microvascular endithelial cell responses to growth factors and haemostatic factors in the presence of vitronectin." Thesis, Queensland University of Technology, 2008. https://eprints.qut.edu.au/37176/1/Peter_Gillies_Thesis.pdf.

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In order to effect permanent closure in burns patients suffering from full thickness wounds, replacing their skin via split thickness autografting, is essential. Dermal substitutes in conjunction with widely meshed split thickness autografts (+/- cultured keratinocytes) reduce scarring at the donor and recipient sites of burns patients by reducing demand for autologous skin (both surface area and thickness), without compromising dermal delivery at the wound face. Tissue engineered products such as Integra consist of a dermal template which is rapidly remodelled to form a neodermis, at which time the temporary silicone outer layer is removed and replaced with autologous split thickness skin. Whilst provision of a thick tissue engineered dermis at full thickness burn sites reduces scarring, it is hampered by delays in vascularisation which results in clinical failure. The ultimate success of any skin graft product is dependent upon a number of basic factors including adherence, haemostasis and in the case of viable tissue grafts, success is ultimately dependent upon restoration of a normal blood supply, and hence this study. Ultimately, the goal of this research is to improve the therapeutic properties of tissue replacements, through impregnation with growth factors aimed at stimulating migration and proliferation of microvascular endothelial cells into the donor tissue post grafting. For the purpose of my masters, the aim was to evaluate the responsiveness of a dermal microvascular endothelial cell line to growth factors and haemostatic factors, in the presence of the glycoprotein vitronectin. Vitronectin formed the backbone for my hypothesis and research due to its association with both epithelial and, more specifically, endothelial migration and proliferation. Early work using a platform technology referred to as VitroGro (Tissue Therapies Ltd), which is comprised of vitronectin bound BP5/IGF-1, aided keratinocyte proliferation. I hypothesised that this result would translate to another epithelium - endothelium. VitroGro had no effect on endothelial proliferation or migration. Vitronectin increases the presence of Fibroblast Growth Factor (FGF) and Vascular Endothelial Growth Factor (VEGF) receptors, enhancing cell responsiveness to their respective ligands. So, although Human Microvascular Endothelial Cell line 1 (HMEC-1) VEGF receptor expression is generally low, it was hypothesised that exposure to vitronectin would up-regulate this receptor. HMEC-1 migration, but not proliferation, was enhanced by vitronectin bound VEGF, as well as vitronectin bound Epidermal Growth Factor (EGF), both of which could be used to stimulate microvascular endothelial cell migration for the purpose of transplantation. In addition to vitronectin's synergy with various growth factors, it has also been shown to play a role in haemostasis. Vitronectin binds thrombin-antithrombin III (TAT) to form a trimeric complex that takes on many of the attributes of vitronectin, such as heparin affinity, which results in its adherence to endothelium via heparan sulfate proteoglycans (HSP), followed by unaltered transcytosis through the endothelium, and ultimately its removal from the circulation. This has been documented as a mechanism designed to remove thrombin from the circulation. Equally, it could be argued that it is a mechanism for delivering vitronectin to the matrix. My results show that matrix-bound vitronectin dramatically alters the effect that conformationally altered antithrombin three (cATIII) has on proliferation of microvascular endothelial cells. cATIII stimulates HMEC-1 proliferation in the presence of matrix-bound vitronectin, as opposed to inhibiting proliferation in its absence. Binding vitronectin to tissues and organs prior to transplant, in the presence of cATIII, will have a profound effect on microvascular infiltration of the graft, by preventing occlusion of existing vessels whilst stimulating migration and proliferation of endothelium within the tissue.
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Books on the topic "Skin-grafting"

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Baronio, Giuseppe. On grafting in animals. Boston: Boston Medical Library, Francis A. Countway Library of Medicine, 1985.

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Gupta, Devendra K. Microskin grafting for vitiligo. Dordrecht: Springer, 2009.

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Chanda, Arnab, Vivek Gupta, and Shubham Gupta. State-of-the-Art in Skin Grafting. Singapore: Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-97-4383-4.

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Terskikh, V. V. Ėpidermalʹnye keratinot͡sity cheloveka i zhivotnykh: Problemy kulʹtivirovanii͡a i transplantat͡sii. Moskva: Nauka, 1995.

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J, Stegman Samuel, and Glogau Richard G, eds. Flaps and grafts in dermatologic surgery. Chicago: Year Book Medical Publishers, 1989.

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Daniel, Buchen, ed. Skin flaps in facial surgery. New York: McGraw-Hill, Medical Pub. Division, 2007.

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M, Evans David, ed. Skin cover in the injured hand. Edinburgh: Churchill Livingstone, 1992.

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Chuong, Ho, and Canadian Coordinating Office for Health Technology Assessment., eds. Artificial skin grafts in chronic wound care: A meta-analysis of clinical efficacy and a review of cost-effectiveness. Ottawa: Canadian Coordinating Office for Health Technology Assessment, 2005.

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Cormack, George C. The arterial anatomy of skin flaps. Edinburgh: Churchill Livingstone, 1986.

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Marwali, Harahap, ed. Principles of dermatologic plastic surgery. New York: PMA Pub. Corp., 1988.

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Book chapters on the topic "Skin-grafting"

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Claeys, Stéphanie. "Skin Grafting." In Complications in Small Animal Surgery, 561–68. Chichester, UK: John Wiley & Sons, Ltd, 2017. http://dx.doi.org/10.1002/9781119421344.ch79.

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Leal-Khouri, Susana M., and Sarah E. Grummer. "Skin Grafting." In Mohs Micrographic Surgery, 433–42. London: Springer London, 2011. http://dx.doi.org/10.1007/978-1-4471-2152-7_34.

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Klein, Matthew. "Skin Grafting." In Color Atlas of Burn Reconstructive Surgery, 132–38. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-05070-1_17.

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Fortier, Jillian L., Charles L. Castiglione, and Lifei Guo. "Skin Grafting." In Interventional Treatment of Wounds, 123–42. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-66990-8_8.

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Karamanos, Efstathios, Bao-Quynh Julian, and Douglas T. Cromack. "Skin Grafting." In Comprehensive Atlas of Upper and Lower Extremity Reconstruction, 29–35. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-74232-4_5.

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Sayyed, Adaah, Paige K. Dekker, Caitlin S. Zarick, and Karen K. Evans. "Skin Grafting." In Functional Limb Salvage, 415–28. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-27725-2_29.

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Schumacher, Jim, and Jacintha M. Wilmink. "Free Skin Grafting." In Equine Wound Management, 422–48. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2016. http://dx.doi.org/10.1002/9781118999219.ch18.

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MacFarlane, Deborah F. "Techniques in Skin Grafting." In Skin Cancer Management, 179–90. New York, NY: Springer New York, 2009. http://dx.doi.org/10.1007/978-0-387-88495-0_13.

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MacFarlane, Deborah F. "Techniques in Skin Grafting." In Skin Cancer Management, 211–23. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-50593-6_13.

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Murakami, Masahiro, Rei Ogawa, and Hiko Hyakusoku. "Tips for Skin Grafting." In Color Atlas of Burn Reconstructive Surgery, 146–57. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-05070-1_19.

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Conference papers on the topic "Skin-grafting"

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Nadhif, Muhammad Hanif, Muhammad Satrio Utomo, Muhammad Farel Ferian, Farhan H. Taufikulhakim, Nadine H. P. Soerojo, Muhammad Dzulkarnaen Nain, Prasandhya A. Yusuf, Anindya P. Susanto, and Theddeus O. H. Prasetyono. "Cost-efficacy of skin grafting techniques using negative pressure wound therapy and tissue-engineered skin for burns." In THE 5TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, AND MEDICAL DEVICES: Proceedings of the 5th International Symposium of Biomedical Engineering (ISBE) 2020. AIP Publishing, 2021. http://dx.doi.org/10.1063/5.0047187.

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Tzong-Shiun Li, Hsu-Fu Wu, Hung-Shu Chen, Chih-Yen Lin, and Kao-Chi Chung. "Electrosurgical tip cleaner: An innovative debriding device for wound prior to skin grafting." In 2011 37th Annual Northeast Bioengineering Conference (NEBEC). IEEE, 2011. http://dx.doi.org/10.1109/nebc.2011.5778522.

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Gurkan, Umut Atakan, Alexandra Dubikovsky, Lynetta J. Freeman, Paul W. Snyder, Russell D. Meldrum, and Ozan Akkus. "In Vivo Actuation System for Mechanostimulation of Large Wound Healing." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53183.

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The incidence of large open wounds in the US is estimated to be about 5–7 million per year which results in a cost of greater than $20 billion for wound management [1]. Large open wounds occur due to burns, trauma, and secondary to surgical interventions, ulcers or pressure sores. The current clinical practice is to treat large open wounds by delayed primary closure where skin is stretched under constant tension to approximate wound edges by relying on the extensibility of the neighboring skin, by skin grafting or by managing the wound to heal by second intention. Delayed primary closure is inapplicable when the strength of the skin is compromised (e.g. age, diabetes). Furthermore, delayed primary closure usually leads to excessive wound tension which introduces hypertrophic scars [2] and ischemia [3] to the skin and the underlying muscles. Skin autografts may result in morbidity of the donor site. Therefore, there is the need for noninvasive methods which will enable large wound closure in a reasonable time frame with minimal scar formation while alleviating or reducing the need for skin graft harvest.
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Ding, Houzhu, Antonio Dole, Filippos Tourlomousis, and Robert C. Chang. "Design of a Skin Grafting Methodology for Burn Wound Using an Additive Biomanufacturing System Guided by Hyperspectral Imaging." In ASME 2016 11th International Manufacturing Science and Engineering Conference. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/msec2016-8588.

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Skin thermal burn wounds are classified by depth and require different levels of medical intervention. In this paper, the authors propose a novel treatment method where hyperspectral imaging (HSI) is applied to measure skin burn wound information that guide an additive biomanufacturing process to print a custom engineered skin graft in three dimensions (3D). Two dimensional principle component analysis (2DPCA) for noise reduction is applied to images captured by HSI in the visible wavelength range from 375 nm to 750 nm. A multivariate regression analysis is used to calculate hemodynamic biomarkers of skin burns, specifically the total hemoglobin concentration (tHb) and oxygen saturation (StO2) of the injured tissue. The biomarker results of the skin burn images are mapped spatially to show the burn wound depth distribution. Based on the biomarker values, the burn area is segmented into different sub areas with different burn degrees. Depth profiles of deep burns which require skin grafting are extracted from the burn distribution map. Next, each profile is processed to generate an additive biomanufacturing toolpath with a prescribed internal tissue scaffold structure. Using the toolpath, a 3D printer processes a custom graft from an alginate polymer hydrogel material. Alginate is chosen as the print material since it can be stretched into aligned fibers to create a porous structure that facilitates oxygen and nutrient uptake. The resultant printed construct demonstrates the feasibility of fabricating patient-specific tissues with custom-geometry grafts for treating clinical burns.
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Ding, Houzhu, Filippos Tourlomousis, Azizbek Babakhanov, and Robert C. Chang. "Design of a Personalized Skin Grafting Methodology Using an Additive Biomanufacturing System Guided by 3D Photogrammetry." In ASME 2015 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/imece2015-51990.

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In this paper, the authors propose a novel method whereby a prescribed simulated skin graft is 3D printed, followed by the realization of a 3D model representation using an open-source software AutoDesk 123D Catch to reconstruct the entire simulated skin area. The methodology is photogrammetry, which measures the 3D model of a real-word object. Specifically, the principal algorithm of the photogrammetry is structure from motion (SfM) which provides a technique to reconstruct a 3D scene from a set of images collected using a digital camera. This is an efficient approach to reconstruct the burn depth compared to other non-intrusive 3D optical imaging modalities (laser scanning, optical coherence tomography). Initially, an artificial human hand with representative dimensions is designed using a CAD design program. Grooves with a step-like depth pattern are then incorporated into the design in order to simulate a skin burn wound depth map. Then, the *.stl format file of the virtually wounded artificial hand is extruded as a thermoplastic material, acrylonitrile butadiene styrene (ABS), using a commercial 3D printer. Next, images of the grooves representing different extents of burned injury are acquired by a digital camera from different directions with respect to the artificial hand. The images stored in a computer are then imported into AutoDesk 123D Catch to process the images, thereby yielding the 3D surface model of the simulated hand with a burn wound depth map. The output of the image processing is a 3D model file that represents the groove on the plastic object and thus the burned tissue area. One dimensional sliced sections of the designed model and reconstructed model are compared to evaluate the accuracy of the reconstruction methodology. Finally, the 3D CAD model is designed with a prescribed internal tissue scaffold structure and sent to the dedicated software of the 3D printing system to print the design of the virtual skin graft with biocompatible material poly-ε-caprolactone (PCL).
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Lentsch, Griffin R., Pezhman Mobasher, Craig Mizzoni, Karsten Koenig, Bruce Tromberg, Irene Georgakoudi, Anand Ganesan, and Mihaela Balu. "In vivo optical imaging of vitiligo skin grafting treatment using multiphoton microscopy and reflectance confocal microscopy (Conference Presentation)." In Photonics in Dermatology and Plastic Surgery 2020, edited by Bernard Choi and Haishan Zeng. SPIE, 2020. http://dx.doi.org/10.1117/12.2544056.

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Gonçalves, Bruno Garcia, Helena Barbosa de Cerqueira Zarur, Rafael Alves Tumeh, and Eduardo Montag. "One-STEP TechniqueTM for harvesting fat graft: A new technology to improve the outcome in breast reconstruction." In Brazilian Breast Cancer Symposium 2023. Mastology, 2023. http://dx.doi.org/10.29289/259453942023v33s1076.

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Objective: The authors present a new technique that provides the harvest of the fat graft and conduct its immediate grafting in the breast reconstructed, after the treatment of breast cancer. Methodology: A total of 42 cases were performed by the senior author from April 2019 to December 2022, in patients submitted to breast reconstruction procedures in private hospitals in Goiânia, Goiás, Brazil. All patients have been submitted to surgical treatment of breast cancer in the past, whether by conservative treatment with partial resection and radiotherapy or any kind of mastectomy and implantbased breast reconstruction. Some patients had adjuvant radiotherapy. The Selective Tissue Engineering Photostimulation Technique (One-STEP TechniqueTM) involves using a diode laser with a wavelength of 1,210 nm applied to the subcutaneous tissue from the abdomen, hips, medial thighs, or axillary extension, before harvesting the fat grafts. The fat graft obtained by the One-STEP technique has innovative characteristics; as the laser is specific for the subcutaneous tissue, it reaches its maximum energy at the adipocytes causing them to vibrate, denaturing the connective tissue and releasing the adipocytes and stromal vascular fraction. The fat grafting was carried out immediately after the fat extraction, as an adjunct to improve the quality of the usual results, and no additional processing steps are required. The evaluation of results was performed at 40 and 90 days postoperatively. Results: The technique features make it easier to aspirate the graft and preserve the viability of cells. The authors observed an excellent take of the grafted fat showing great improvement in the skin quality and reduced formation of oil cysts and calcifications. Some patients showed great improvement even in radiated skin. Conclusion: The One-STEP TechniqueTM is an excellent alternative to improve the quality of the fat graft in order to achieve a more aesthetic breast reconstruction.
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Sojka, Erik S., Ulysses Balis, Robert Sheridan, and Alex Fowler. "Exploration of an Animal Model for Hypertrophic Scar Formation." In ASME 1999 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1999. http://dx.doi.org/10.1115/imece1999-0582.

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Abstract In this paper we investigate the possibility of creating an animal model for hypertrophic scar formation by grafting healthy split thickness human skin onto the backs of athymic nude mice and then burning the grafts. We were able to show that the human tissue grafts do remain stable over extended periods and prove that the human dermis does not get infiltrated by mouse tissue. By burning the grafts for ten seconds at 70°C we found that we could not reproduce results previously reported; but by changing the burn parameters we were able to produce regions of dermal disorder that may indicate the formation of hypertrophic scar. These results represent the first replication of positive results using this animal model since it was first proposed 10 years ago.
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Paulinelli, Régis Resende, Luiz Fernando Jubé Ribeiro, Thauana Dias Santos, Elisana Maria Santos Caires, Marilha Gabriella Martins Pontes, and Bruna Morais Faria. "ONCOPLASTIC MAMMAPLASTY WITH DISGUISED GEOMETRIC COMPENSATION." In Abstracts from the Brazilian Breast Cancer Symposium - BBCS 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s2020.

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Objective: To evaluate the results and follow-up of retrospective cohort of patients submitted to a new technique of oncoplastic mammaplasty, referred to as disguised geometric compensation mammaplasty (DGCM), which is suitable for tumors involving the glandular tissue in the lateral or medial pillars of the mammaplasty. Materials and Methods: A total of 25 patients with breast tumor involving the pillars of the mammaplasty were included, of whom 20 (80.00%) had invasive ductal carcinoma, 3 (12.00%) had phyllodes tumor, 1 (4.00%) had invasive lobular carcinoma, and 1 (4.00%) had in situ ductal carcinoma. Preoperative markings followed the “Wise-pattern” technique. The resection of the tumor in the pillar of the mammaplasty, preserving the overlying skin, was geometrically compensated with a correspondent area coming from the lower poles, which folds over itself and maintains the skin vascularity in the pillar. One patient was converted to classic geometric compensation due to a positive skin margin in the frozen section. Other patient combined a classic geometric compensation for the inner quadrants and DGCM for the outer quadrants in the same breast. One patient decided to submit to a bilateral mastectomy after adjuvant chemotherapy because of a BRCA2 mutation. Immediate fat grafting was done in one case. Approval from the ethics committee: n. 2.322.212. Results: Mean age was 46.96±9.53 years. Mean clinical tumor size was 47.21±22.16 mm before chemotherapy and 36.67±22.5 mm after chemotherapy. There were 11 (44.00%) locally advanced and 1 (4.00%) multicentric tumor. Nine (36.00%) patients were submitted to neoadjuvant chemotherapy. Adjuvant chemotherapy, endocrine therapy, and radiotherapy were indicated according to the necessity. Ptosis was corrected in all cases. The aesthetic results were rated as excellent or good in 21 cases (95.45%) by the Harvard scale and the BCCT.core. Three patients have not returned for the aesthetic evaluation after surgery. The BREAST-Q scores for the satisfaction with the breasts and satisfaction with outcomes were 81.50 (±15.00) and 90.44 (±11.70), respectively. Intraoperative frozen sections were done in 12 (48%) cases. There were two (8.00%) positive margins. One focus of DCIS in the skin margin was treated with radiotherapy, and the other positive margin was treated with re-excision. The complications were: three (12.00%) small wound dehiscences, two (8.00%) small skin necrosis, and two (8.00%) local hyperemia treated with antibiotics, two (8.00%) enlarged scars, and one (4.00%) small hematoma. There were not reoperations to treat complications. There was 1 (4.00%) local recurrence in the breast and axilla after 11 months, treated with radical mastectomy, and 1 (4.00%) metastasis to the brain after 3 months. No deaths were observed within a mean follow-up time of 16.28±11.39 months. Conclusion: The technique allowed breast conservation in situations requiring large resection in the pillars of the mammaplasty, with a high rate of free margins, correction of ptosis, satisfactory symmetry, and few complications.
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Clarke, Paula, Douglas de Miranda Pires, and Jéssica Moreira Cavalcante. "3D TATTOO OF THE NIPPLE-AREOLA COMPLEX AS A COMPLETION OF BREAST RECONSTRUCTION: CASE REPORT." In Scientifc papers of XXIII Brazilian Breast Congress - 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s1075.

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Introduction: Reconstruction of the nipple-areola complex (NAC) is the last step in breast reconstruction after a radical mastectomy. There are several techniques to perform NAC reconstruction and the most common described involve local flaps and skin grafts. However, they depend on good vascularization at the receptor site, which is often impaired in mastectomies with prosthetic reconstruction, often associated with an irradiated tissue, increasing risk of ischemia and necrosis of the new NAC. Tattooing of the NAC is an alternative to the surgical procedures and has gained space over the years, due to its ease, rapid recovery, and low rate of complications. A tattoo consists in placing pigments in the dermis, through perforations in the skin by different combinations of needles, called cartridges. Such pigments are currently synthetic, based on iron oxides and titanium dioxides dispersed in a suspended gel, offering safety with rare adverse events. Case report: Female, 62 years old, who had a modified radical mastectomy in 2008 for treatment of invasive breast cancer in another institution. In 2012, she started her follow-up at Santa Casa de Misericórida de Belo Horizonte and had a reconstruction using a latissimus dorsi myocutaneous flap with a prosthesis, associated with skin grafting for reconstruction of the areola and papilla and a reduction mammaplasty on the left. After discussing options and understanding patients’ expectations, an oval areola on the right was planned, similar to the left one. Lidocaine based topical anesthetics was applied, followed by a complete tattoo of the right NAC, using a 3D technique for the papilla. The machine used was TH PRO NeonPEN Slim® and needle cartridges 1RL, 3RL, 5RS and 7RM from the same brand. Dressing was performed with La Roche Cicaplast® ointment, covered with a plastic film, which was changed daily by the patient for 15 days, according to medical advice. After 40 days the bilateral oval shape. However, the patient was not satisfied, so we planned to transform it into a round areola. Tattooing of the round areola and retouching of details for the right papilla were performed, in addition to the left areola pigmentation, to symmetrize color and shape. Figure 3 illustrates the results 15 days after the second and last session, with similarity between color and areolar shape, as well as an effect of depth and projection on the right papilla. A subjective evaluation of outcome was carried out, with the patient claiming satisfaction with the procedure and feeling better about her breasts.
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Reports on the topic "Skin-grafting"

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Pan, Junqing, Xiangjun Hu, Hongwei Yin, Congzhong Zhang, and Zhangren Yan. Effectiveness of different types of skin grafting for treating venous leg ulcers: a systematic review and network meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, March 2021. http://dx.doi.org/10.37766/inplasy2021.3.0093.

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