Relevant bibliographies by topics / Skin infections

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Skin infections'

Author: Grafiati
Published: 4 June 2021
Last updated: 16 June 2025

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Journal articles on the topic "Skin infections"

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Inda Astri, Fitirani, and Dewi. "Control and Prevention of Transmission of Skin Infections." Conferences of Medical Sciences Dies Natalis Faculty of Medicine Universitas Sriwijaya 2, no. 1 (2020): 113–19. http://dx.doi.org/10.32539/dies.v2i1.48.

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Skin infections are the most common skin diseases found in densely populated, slum neighborhoods including boarding schools / pesantren. Skin infections can occur at any age, closely related to environmental influences, hosts and causative agents. Common skin infections in congested conditions are scabies infestations, dermatophytosis and pyoderma. Knowledge of skin infection symptoms, personal and environmental hygiene are also determinants of disease transmission. Some efforts to control and prevent the transmission of skin infections include screening for infectious diseases, treatment and providing counseling about skin diseases and ways to prevent transmission.
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Brigden, D. "SKIN INFECTIONS." British Medical Bulletin 41, no. 4 (1985): 357–60. http://dx.doi.org/10.1093/oxfordjournals.bmb.a072076.

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Clebak, Karl T., and Michael A. Malone. "Skin Infections." Primary Care: Clinics in Office Practice 45, no. 3 (2018): 433–54. http://dx.doi.org/10.1016/j.pop.2018.05.004.

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Watson, Jacqueline Ann, and Sandra Lawton. "Skin infections." Primary Health Care 28, no. 3 (2018): 42–49. http://dx.doi.org/10.7748/phc.2018.e1365.

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Herzog, Mackenzie M., Melissa A. Fraser, Johna K. Register-Mihalik, and Zachary Y. Kerr. "Epidemiology of Skin Infections in Men's Wrestling: Analysis of 2009–2010 Through 2013–2014 National Collegiate Athletic Association Surveillance Data." Journal of Athletic Training 52, no. 5 (2017): 457–63. http://dx.doi.org/10.4085/1062-6050-52.2.16.

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Context: Our knowledge of the current epidemiology of skin infections among wrestlers is limited. Objective: To analyze and report the epidemiology of skin infections among National Collegiate Athletic Association (NCAA) men's wrestling student-athletes during the 2009–2010 through 2013–2014 academic years. Design: Descriptive epidemiology study. Setting: Aggregate skin infection and exposure data collected by the NCAA Injury Surveillance Program. Patients or Other Participants: Collegiate men's wrestling student-athletes. Main Outcome Measure(s): All viral, bacterial, or fungal skin infections reported by athletic trainers at 17 NCAA programs were analyzed, providing 35 team-seasons of data. Skin infection rates per 10 000 athlete-exposures (AEs), rate ratios, skin infection proportions, and skin infection proportion ratios were calculated. Results: The athletic trainers reported 112 skin infections contracted by 87 student-athletes across 78 720 AEs. The overall skin infection rate was 14.23/10 000 AEs (95% confidence interval [CI] = 11.59, 16.86). Of the skin infections identified, 22.3% (n = 25) were recurrent skin infections. Most skin infections (65.2%) were attributable to 5 team-seasons (range, 11–19 infections). Most skin infections occurred during the regular season (n = 76, 67.9%), were identified during practice (n = 100, 89.3%), and resulted in ≥24 hours' time loss (n = 83, 74.1%). The rate for viral skin infections was 1.72 times the rate for bacterial skin infections (95% CI = 1.09, 2.72) and 2.08 times the rate for fungal skin infections (95% CI = 1.28, 3.39). Fungal skin infections more often resulted in time loss <24 hours compared with all other skin infections (75.0% versus 12.5%; infection proportion ratio = 6.00; 95% CI = 3.30, 10.92). Conclusions: Our findings highlight the contagiousness of skin infections and suggest that skin infection rates may be attributable to high incidences among particular teams.
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Abrahamian, Fredrick M., George Sakoulas, Evan Tzanis, et al. "Omadacycline for Acute Bacterial Skin and Skin Structure Infections." Clinical Infectious Diseases 69, Supplement_1 (2019): S23—S32. http://dx.doi.org/10.1093/cid/ciz396.

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Abstract Background Within the last decade, methicillin-resistant Staphylococcus aureus (MRSA) has emerged as a frequent cause of purulent skin and soft tissue infections. New therapeutic options are being investigated for these infections. Methods We report an integrated analysis of 2 randomized, controlled studies involving omadacycline, a novel aminomethylcycline, and linezolid for the treatment of acute bacterial skin and skin structure infections (ABSSSI). Omadacycline in Acute Skin and Skin Structure Infections Study 1 (OASIS-1) initiated patients on intravenous omadacycline or linezolid, with the option to transition to an oral formulation after day 3. OASIS-2 was an oral-only study of omadacycline versus linezolid. Results In total, 691 patients received omadacycline and 689 patients received linezolid. Infection types included wound infection in 46.8% of patients, cellulitis/erysipelas in 30.5%, and major abscess in 22.7%. Pathogens were identified in 73.2% of patients. S. aureus was detected in 74.7% and MRSA in 32.4% of patients in whom a pathogen was identified. Omadacycline was noninferior to linezolid using the Food and Drug Administration primary endpoint of early clinical response (86.2% vs 83.9%; difference 2.3, 95% confidence interval –1.5 to 6.2) and using the European Medicines Agency primary endpoint of investigator-assessed clinical response at the posttreatment evaluation. Clinical responses were similar across different infection types and infections caused by different pathogens. Treatment-emergent adverse events, mostly described as mild or moderate, were reported by 51.1% of patients receiving omadacycline and 41.2% of those receiving linezolid. Conclusions Omadacycline was effective and safe in ABSSSI. Clinical Trials Registration NCT02378480 and NCT02877927.
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Várvölgyi, Tünde. "Viral skin diseases in childhood." Bőrgyógyászati és Venerológiai Szemle 97, no. 2 (2021): 100–106. http://dx.doi.org/10.7188/bvsz.2021.97.2.5.

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Some of the dermatological viral infections occur primarily in childhood, and are referred to as classic childhood viral infectious diseases. The incidence and appearance of primary skin infections may also differ from the adult variant. In our paper, we summarized the primary skin infections, the classic viral infectious diseases of childhood from infancy to the later stages of childhood. Tentatively, we mention other, not classically, childhood viral infections.
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White, Skyler M., Katrina N. Kesterson, and Michael G. Wilkerson. "Persistent Cutaneous Infection Due to Mycobacterium Immunogenum, a Relatively Novel Species." SKIN The Journal of Cutaneous Medicine 2, no. 1 (2018): 69–74. http://dx.doi.org/10.25251/skin.2.1.11.

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Mycobacterium immunogenum is a species of nontuberculous mycobacteria (NTM) that has been recently identified as the cause of cutaneous infections.1-3 Historically, the majority of NTM infections were attributed to contamination of municipal water systems due to inadequate equipment sterilization. Many of these organisms have been found to grow in distilled water and display resistance to chlorine, formaldehyde, mercury, and standard disinfectants.4 In the environment, M. immunogenum has been isolated in swimming pools and adjacent showers.5 A limited number of cutaneous infections with Mycobacterium immunogenum have been reported, and an even smaller number of cases have been reported in immunocompetent individuals. We report a case of a persistent cutaneous infection with M. immunogenum in a previously healthy patient successfully treated with clarithromycin 250 mg twice daily for eight weeks. After treatment, the patient remained free of infection and only a minimal scar remained.
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Dinçer Rota, Didem, and Mehmet Can Emeksiz. "Granulomatous skin infections." TURKDERM 55, no. 1 (2021): 1–8. http://dx.doi.org/10.4274/turkderm.galenos.2020.16362.

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Gupta, Aditya K., Melissa A. MacLeod, Kelly A. Foley, Gita Gupta, and Sheila Fallon Friedlander. "Fungal Skin Infections." Pediatrics in Review 38, no. 1 (2017): 8–22. http://dx.doi.org/10.1542/pir.2015-0140.

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Dissertations / Theses on the topic "Skin infections"

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Egan, Jonathon Todd. "Chiropractic Student Infection Control Practices and Methicillin-Resistant Staphylococcus aureus Skin Infections." ScholarWorks, 2016. https://scholarworks.waldenu.edu/dissertations/2027.

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Chiropractic training involves many hours of skin contact, and chiropractors have manual contact with millions of patients annually, but chiropractic has only had professional clinical hygiene guidance since 2010. Methicillin-resistant Staphylococcus aureus (MRSA) is the most common cause of cultured skin and soft tissue infection (SSTI) in the United States. Using the epidemiologic triad of person, place, and time as a framework, this quantitative, cross-sectional study obtained the first assessment of MRSA SSTI incidence among chiropractic students and its association with infection control behaviors (hand and table hygiene, sharing gowns, and sharing lotion) and initiation of patient care. The study obtained surveys from 312 students attending half (9/18) of U.S. chiropractic campuses. Associations were assessed by Ï?2 and Fisher's exact test. Stratum specific effects were assessed. Two logistic regression models were produced. The results were that attendance at Campus 6 was associated with postmatriculation MRSA SSTI in univariate analysis, p = 0.010. There was an interaction between campus attended, sharing lotion, and postmatriculation MRSA SSTI, with the Mantel-Haenszel pooled estimate varying significantly from unity, Ï?2 (1) = 6.75, p = 0.009. No other association between any assessed factor and MRSA SSTI was detected. Logistic regression models were significant (p < 0.05), but the composing variables were not. For social change, chiropractic colleges should instruct students and chiropractic associations could encourage members not to share massage lotions and emollients during the practice of manual therapy to help prevent MRSA SSTI.
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Rybak, Michael Rybak. "Risk Factors and Outcomes for Bloodstream Infections Among Patients with Skin Infections." ScholarWorks, 2016. https://scholarworks.waldenu.edu/dissertations/3069.

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Acute bacterial skin and skin structure infections (ABSSSI) are common infections within the local community, and they result in higher morbidity and health care costs. While risk factors for skin and soft tissue infections have been previously evaluated, risk factors associated with secondary bloodstream infections (BSI) has not been investigated, especially in an intercity patient population with limited health care resources. In this case control investigation, 392 patients consisting of 196 cases (ABSSSI + BSI) and 196 controls (ABSSSI) were investigated to determine risk for BSI. Both sociodemographic and underlying conditions were evaluated. According to bivariate analysis of cases and controls, individuals with ABSSSI + BSI were significantly older (p < 0.001), more often male (p = 0.008), and had a higher percentage of abnormal symptoms, such as elevated temperature, white blood cell count, and acute renal failure on hospital admission (p < 0.001). Individuals with ABSSSI + BSI also had a higher percentage of chronic renal failure (p = 0.002), diabetes (p = 0.005), congestive heart failure (p = 0.012), intravenous drug use (p =0.012), and a history of prior hospitalization (p < 0.001). Several of these factors remained statistically significant by logistic regression analysis, such as male gender aOR of 1.85, 95% CI 1.11-3.66; acute renal failure aOR 2.08, 95% CI 1.18-3.67; intravenous drug use aOR 4.38, 2.22-8.62; and prior hospitalization aOR 2.41, 95% CI 1.24-4.93. This study contributes to positive social change by identifying patient characteristics that are associated with ABSSSI-related BSI, thus providing health care providers the ability to improve patient outcomes in this underserved patient population.
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Ko, Hean Teik Humphrey. "Investigating the Relationship Between Statins and Bacterial Skin Infections." Thesis, Curtin University, 2019. http://hdl.handle.net/20.500.11937/77546.

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Statins are extensively prescribed medicines to reduce cholesterol for cardioprotection, but they also exhibit antimicrobial and pleiotropic effects, which plausibly reduces both skin infection risks and antimicrobial resistance. Adopting a bench-to-bedside framework, the results of laboratory experiments (identifying suitable statins as topical antibiotics and postulating a mechanism of antibacterial action) and clinical evidence (via prescription sequence symmetry analysis and a retrospective case-control study) were reconciled to determine if prior statin use translated into beneficial outcomes.
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Abel, Svenja [Verfasser], Siobhan O. Akademischer Betreuer] Burns, and Bodo [Akademischer Betreuer] [Grimbacher. "The characteristics of viral skin infections in the immunocompromised host." Freiburg : Universität, 2019. http://d-nb.info/1197536426/34.

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Bounyadeth, Somboun. "Cutaneous findings in HIV positive patients at Pramongkutklao Hospital Skin Clinic /." Abstract, 1999. http://mulinet3.li.mahidol.ac.th/thesis/2542/42E-SombuanB.pdf.

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Little, Charlene Knight. "Decreasing Surgical Site Infections in Vascular Surgery Patients." ScholarWorks, 2016. https://scholarworks.waldenu.edu/dissertations/2412.

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Postoperative surgical site infections are common complications in the operating room. Infections prolong hospital stays, heighten costs, and increase morbidity and mortality. The purpose of this evidence-based quality improvement project was to develop policy, program, and practice guidelines to prevent surgical site infections in vascular surgery patients. Rosswurm and Larrabee's change model was used to develop materials using the best evidence for the recommended practice changes. The Plan, Do, Check, Act model was selected to guide quality improvement. The project goal was to decrease the surgical site infection rate to below the national average. Products of the project include policy, protocol, and practice guidelines developed based on recommended practices of the Association of periOperative Registered Nurses and current peer-reviewed literature. An interdisciplinary project team of institutional stakeholders was used to insure context-relevant operationalization of the evidence in practice. The team was assembled, led in a review of relevant literature, and convened regularly until project products were finished. Three scholars with expertise in the content area were then identified by the project team and asked to validate the content of developed products. Products were revised according to expert feedback. Implementation and evaluation plans were developed by the project team to provide the institution with all necessary process details to carry out the practice change. The evaluation plan advises using a retrospective chart review to compare rates of infection between patients receiving chlorhexidine skin preparation with showers and preoperative chlorhexidine cloths alone. A positive outcome could contribute to positive social change by decreasing preventable infections.
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Ifebuzor, Deciderius Chika. "“The determinants of the help seeking behaviour of parents having children with minor illness in Francistown, Botswana : “Case Study of Fungal Skin Infection”." Thesis, University of Limpopo (Medunsa Campus), 2010. http://hdl.handle.net/10386/207.

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Thesis (M Med.(Family Medicine))--University of Limpopo, 2010.<br>Aim: To understand the help seeking behaviour of parents having children with minor illnesses such as fungal skin infection and to respond appropriately to such behaviours. Design: A descriptive qualitative study using the free attitude interview technique Method: The study was conducted in Francistown City Council Clinics. Eight participants were interviewed. Using purposeful sampling chose the participants. Each respondent was asked the same exploratory question “How much do you know about this skin infection?” Exploratory question (Setswana) is “O itse go le kae ka bolwetsi jone jo jwa letlalo?” The probe follow up questions were used to encourage elaboration on the topic. The discussions were held in Setswana language. The interviews were audio – taped. The recordings were transcribed, and the ideas that emerged were developed into themes. Results: Most of the respondents believed that Skin fungal infection was common in the community and it was generally called skin rash. It was believed to be infectious that it may be associated with HIV infection. Some however believe that its cause was known and it was treatable The help seeking behaviour of parents having children with minor illness like skin fungal infection falls within these reasons: Availability of alternative treatment, Concern of the child especially if the child complains about the problem, 6 Concern of the parents when the parents consider such minor health concern as a health problem for the child, issues around difficult in management of the problem, If problem is tolerable. Conclusion: Residents of Francistown city council, which was where the study was carried out perceived skin fungal infection as a common infectious skin problem, that is treatable. There is adequate knowledge of the symptoms of skin fungal infection among the participants. Some of the participants believed that skin fungal infection is common in children because they see the skin lesion as a normal change in colour for children before adult life. It was believe that as they get older the change in colour will then disappear. Many of them believe that they do not know the cause and even the few that felt that they knew the cause could not give a good account of the exact cause of the skin fungal infection, only one said that it is caused by a germ. Most of the participants were aware that it is treatable but yet they were not keen seeking for help when they come to the clinics because of one or two of the following reasons: Availability of alternative treatment; Concern of the child especially if the child complains about the problem; Concern of the parents when the parents consider such minor health concern as a health on the child; Issues around difficult in management of the problem; Health problem being tolerable
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Hussain, Malik Asif. "Comparative study of coagulase negative Staphylococci (CoNS) from clinical isolates, skin and nasal sources." Thesis, Queensland University of Technology, 2011. https://eprints.qut.edu.au/47603/1/Malik_Hussain_Thesis.pdf.

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Staphylococci are important pathogenic bacteria responsible for a range of diseases in humans. The most frequently isolated microorganisms in a hospital microbiology laboratory are staphylococci. The general classification of staphylococci divides them into two major groups; Coagulase-positive staphylococci (e.g. Staphylococcus aureus) and Coagulase-negative staphylococci (e.g. Staphylococcus epidermidis). Coagulase-negative staphylococcal (CoNS) isolates include a variety of species and many different strains but are often dominated by the most important organism of this group, S. epidermidis. Currently, these organisms are regarded as important pathogenic organisms causing infections related to prosthetic materials and surgical wounds. A significant number of S. epidermidis isolates are also resistant to different antimicrobial agents. Virulence factors in CoNS are not very clearly established and not well documented. S. epidermidis is evolving as a resistant and powerful microbe related to nosocomial infections because it has different properties which independently, and in combination, make it a successful infectious agent, especially in the hospital environment. Such characteristics include biofilm formation, drug resistance and the evolution of genetic variables. The purpose of this project was to develop a novel SNP genotyping method to genotype S. epidermidis strains originating from hospital patients and healthy individuals. High-Resolution Melt Analysis was used to assign binary typing profiles to both clinical and commensal strains using a new bioinformatics approach. The presence of antibiotic resistance genes and biofilm coding genes were also interrogated in these isolates.
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Vestey, James Patrick. "Antigen presentation and systemic immune responses to herpes simplex virus in patients with recrudescent facial herpetic infections." Thesis, University of Southampton, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.259925.

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Hanboula, Salem Yousef. "Immunological characterisation of dermatophytes." Thesis, University of Liverpool, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243208.

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Books on the topic "Skin infections"

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Bonamonte, Domenico, and Gianni Angelini, eds. Mycobacterial Skin Infections. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-48538-6.

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Marwali, Harahap, ed. Mycobacterial skin diseases. Kluwer Academic Publishers, 1989.

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Vivier, Anthony Du. Atlas of infections of the skin. Gower Medical Pub., 1991.

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Marwali, Harahap, ed. Diagnosis and treatment of skin infections. Blackwell Science, 1997.

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E, Elewski Boni, ed. Cutaneous fungal infections. 2nd ed. Blackwell Science, 1997.

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Findlay, George Hudson. The dermatology of bacterial infections. Blackwell Scientific, 1987.

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Findlay, George Hudson. The dermatology of bacterial infections. Blackwell Scientific, 1987.

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Al-Zay, Saleh. Infectious skin diseases: Medical subject analysis and research bibliography. Abbe Publishers Association, 1985.

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L, Lesher John, and Aly Raza, eds. An atlas of microbiology of the skin. Parthenon Pub. Group, 2000.

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A, Witkowski Joseph, and Vassileva Snejina, eds. Color atlas of cutaneous infections. Blackwell Scientific, 1995.

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Book chapters on the topic "Skin infections"

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Brooks, D., and E. M. Dunbar. "Skin Infections." In Infectious Diseases. Springer Netherlands, 1986. http://dx.doi.org/10.1007/978-94-009-4133-5_12.

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Marks, Melvin I. "Skin Infections." In Pediatric Infectious Diseases for the Practitioner. Springer New York, 1985. http://dx.doi.org/10.1007/978-1-4612-5038-8_7.

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Webber, R. "Skin infections." In Communicable diseases: a global perspective. CABI, 2016. http://dx.doi.org/10.1079/9781780647425.0151.

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Webber, R. "Skin infections." In Communicable diseases: a global perspective. CABI, 2016. http://dx.doi.org/10.1079/9781780647425.0165.

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Webber, R. "Skin infections." In Communicable diseases: a global perspective. CABI, 2020. http://dx.doi.org/10.1079/9781786395245.0165.

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Rihana, Nancy, and Mindy Sampson. "Skin Infections." In Infections in Neutropenic Cancer Patients. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-21859-1_5.

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Bensouilah, Janetta, Philippa Buck, Robert Tisserand, and Angela Avis. "Skin infections." In Aromadermatology. Routledge, 2021. http://dx.doi.org/10.4324/9781785230974-7.

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Dawood, Mary, and Robin Touquet. "Skin infections." In The Emergency Practitioner's Handbook. CRC Press, 2021. http://dx.doi.org/10.1201/9781846198366-32.

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Marks, Ronald, Arthur Knight, and P. Laidler. "Infections." In Atlas of Skin Pathology. Springer Netherlands, 1986. http://dx.doi.org/10.1007/978-94-009-4127-4_4.

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Hay, Roderick J. "Fungal Infections." In Imported Skin Diseases. John Wiley & Sons, Inc., 2012. http://dx.doi.org/10.1002/9781118472620.ch6.

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Conference papers on the topic "Skin infections"

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Foradori, Dana, Sowdhamini Wallace, Michelle Lopez, et al. "Prevalence of Invasive Bacterial Infections in Infants <60 Days with Skin and Soft Tissue Infections." In Selection of Abstracts From NCE 2016. American Academy of Pediatrics, 2018. http://dx.doi.org/10.1542/peds.141.1_meetingabstract.428.

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Lei, Xia, and Yang Tan. "Effect and mechanisms of photodynamic therapy in treating chronic skin ulcers infected with Pseudomonas aeruginosa (Conference Presentation)." In Photonic Diagnosis and Treatment of Infections and Inflammatory Diseases, edited by Tianhong Dai. SPIE, 2018. http://dx.doi.org/10.1117/12.2289032.

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Kolb, Juergen F., Loree C. Heller, Taranjeet Singh, Angela M. Bowman, R. James Swanson, and Karl H. Schoenbach. "Treatment of skin infections with DC operated afterglow air plasma jet." In 2010 IEEE 37th International Conference on Plasma Sciences (ICOPS). IEEE, 2010. http://dx.doi.org/10.1109/plasma.2010.5534248.

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Radhakrishnan, Geethanjali, Aayush G. Gupta, John King, and Devina Ganvir. "Rapid handheld screening device to detect skin and soft tissue infections." In Photonics in Dermatology and Plastic Surgery 2020, edited by Bernard Choi and Haishan Zeng. SPIE, 2020. http://dx.doi.org/10.1117/12.2546404.

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Gostin, Irina Neta. "SEM INVESTIGATIONS OF SKIN BACTERIAL INFECTIONS IN TWO ASIATIC CYPRINIDS SPECIES." In SGEM2011 11th International Multidisciplinary Scientific GeoConference and EXPO. Stef92 Technology, 2011. http://dx.doi.org/10.5593/sgem2011/s20.160.

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Kirkorian, Yasmine, and Susanne Kammerer. "Fungal skin infections in children: A diagnosis to keep in mind." In 2022 American Academy of Dermatology Annual Meeting, edited by Peter van de Kerkhof. Medicom Medical Publishers, 2022. http://dx.doi.org/10.55788/245e5337.

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Kirkorian, Yasmine, and Susanne Kammerer. "Fungal skin infections in children: A diagnosis to keep in mind." In 2022 American Academy of Dermatology Annual Meeting, edited by Peter van de Kerkhof. Medicom Medical Publishers, 2022. http://dx.doi.org/10.55788/b8230abc.

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Fricke, Dierk, Stephan Maas, Lennart Jütte, Merve Wollweber, and Bernhard Roth. "Non-contact fast Mueller matrix measurement system for investigation of inflammatory skin diseases." In Photonic Diagnosis, Monitoring, Prevention, and Treatment of Infections and Inflammatory Diseases 2019, edited by Tianhong Dai, Mei X. Wu, and Jürgen Popp. SPIE, 2019. http://dx.doi.org/10.1117/12.2509766.

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Cardillo, Holly, Jennifer Kohler, Ellie Kriner, and Khanjan Mehta. "Applications of Wood's Lamp technology to detect skin infections in resource-constrained settings." In 2014 IEEE Global Humanitarian Technology Conference (GHTC). IEEE, 2014. http://dx.doi.org/10.1109/ghtc.2014.6970337.

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Caglar, Derya, Lauren Wilson, Matthew P. Kronman, Surabhi Vora, Casey Lion, and Lori Rutman. "Standardizing Care for Skin and Soft Tissue Infections in Children: Impact on Antimicrobial Stewardship." In Selection of Abstracts From NCE 2016. American Academy of Pediatrics, 2018. http://dx.doi.org/10.1542/peds.141.1_meetingabstract.359.

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Reports on the topic "Skin infections"

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Lollis, Blake D., and Robert S. Kent. Cluster of Nontuberculous Mycobacteria Skin Infections from Tattoos. Defense Technical Information Center, 2010. http://dx.doi.org/10.21236/ada523390.

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Armstrong, Anthony Q., Jennifer L. Goldberg, Marilyn E. Langston, and Lee Ann Wilson. Topical Pathogens, Topical (Skin) Infections, and Cosmetics Periodic Update (July 1, 2016 to June 30, 2017). Office of Scientific and Technical Information (OSTI), 2017. http://dx.doi.org/10.2172/1476415.

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Bradley, Linda Arthur, Deborah Christel, Megan Vulcan, and Susan Dunn. The Use of TransDRY® Cotton Fabric as a textile intervention to Reduce Abdominal Skin Infections and Surface Skin Temperature in Post-Bariatric Surgery Patients. Iowa State University, Digital Repository, 2017. http://dx.doi.org/10.31274/itaa_proceedings-180814-320.

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Wu, Jiangfeng, Yunlai Wang, and Zhengping Wang. Role of Point-of-Care Ultrasound in the Dignosis of Abscess in Pediatric Skin and Soft Tissue Infections: A Protocol of Systematic Review and Meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2021. http://dx.doi.org/10.37766/inplasy2021.1.0063.

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Cabrera, Anahi Maldonado, Blayra Maldonado Cabrera, Dalia Isabel Sánchez Machado, and Jaime López Cervantes. Wound healing therapeutic effect of chitosan nanofibers: a systematic review and meta- analysis of animal studies. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.10.0121.

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Review question / Objective: Review question: Does chitosan base nanofibers has significant wound healing therapeutics effects in animal models? A preclinical systematic review of intervention will be carried out to evaluate the therapeutic effects of chitosan nanofibers on animal skin lesions. The PICO (Population, Intervention, Comparator, Outcome) scheme will be used: Intervention: full-thickness skin lesions, and the application of chitosan nanofibers as treatment for animal skin lesions. Regardless of the concentration of chitosan or other added compounds used. Comparison: No intervention, topical placebo agents and standard skin lesions treatments will be included. Outcome: wound healing area, wound closure, type of wound closure (first, second or third intention), healing time, infectious processes (antibacterial/antifungal properties), blood loss (hemostatic properties) and adverse effects.
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Noga, Edward J., Ramy R. Avtalion, and Michael Levy. Comparison of the Immune Response of Striped Bass and Hybrid Bass. United States Department of Agriculture, 1993. http://dx.doi.org/10.32747/1993.7568749.bard.

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We developed methods for examining the pathophysical response of striped bass and hybrid bass to various forms of stress. This involved development of techniques for the measurement of lysozyme, mitogen blastogenesis, mixed lymphocyte reaction, and oxidative burst, which are important general indicators of systemic immune function. We also examined local immune defenses (epithelial integrity), as well as homeostatic indicators in blood, including osmotic balance and glucose. Acute stress resulted in significant perturbations in a number of parameters, including glucose, electrolytes, osmolarity, lysozyme, and mixed lymphocyte reaction. Most significantly, acute confinement stress resulted in severe damage to the epidermal epithelium, as indicated by the rapid (within 2 hr) development of erosions and ulcerations on various fins. There were significant differences in the resting levels of some immune functions between striped bass and hybrid bass, including response to mitogens in the leukocyte blastogenesis test. Our studies also revealed that there were significant differences in how striped bass and hybrid bass respond to stress, with striped bass being much more severely affected by stress than the hybrid. This was reflected in more severe changes in glucose, cortisol dynamics, and plasma lysozyme. Most significantly, striped bass developed more severe idiopathic skin ulceration after stress, which may be a major reason why this fish is so prone to develop opportunistic bacterial and fungal infections after stress. Hybrid bass injected with equine serum albumin developed a typical humoral immune response, with peak antibody production 28 days after primary immunization. Fish that were exposed to a chronic stress after a primary immunization showed almost complete inhibition of antibody production.
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Matthew, Gray. Data from "Winter is Coming – Temperature Affects Immune Defenses and Susceptibility to Batrachochytrium salamandrivorans". University of Tennessee, Knoxville Libraries, 2021. http://dx.doi.org/10.7290/t7sallfxxe.

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Environmental temperature is a key factor driving various biological processes, including immune defenses and host-pathogen interactions. Here, we evaluated the effects of environmental temperature on the pathogenicity of the emerging fungus, Batrachochytrium salamandrivorans (Bsal), using controlled laboratory experiments, and measured components of host immune defense to identify regulating mechanisms. We found that adult and juvenile Notophthalmus viridescens died faster due to Bsal chytridiomycosis at 14 ºC than at 6 and 22 ºC. Pathogen replication rates, total available proteins on the skin, and microbiome composition likely drove these relationships. Temperature-dependent skin microbiome composition in our laboratory experiments matched seasonal trends in wild N. viridescens, adding validity to these results. We also found that hydrophobic peptide production after two months post-exposure to Bsal was reduced in infected animals compared to controls, perhaps due to peptide release earlier in infection or impaired granular gland function in diseased animals. Using our temperature-dependent infection results, we performed a geographic analysis that suggested that N. viridescens populations in the northeastern United States and southeastern Canada are at greatest risk for Bsal invasion. Our results indicate that environmental temperature will play a key role in the epidemiology of Bsal and provide evidence that temperature manipulations may be a viable Bsal management strategy.
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Evans, Donald L., Avigdor Eldar, Liliana Jaso-Friedmann, and Herve Bercovier. Streptococcus Iniae Infection in Trout and Tilapia: Host-Pathogen Interactions, the Immune Response Towards the Pathogen and Vaccine Formulation. United States Department of Agriculture, 2005. http://dx.doi.org/10.32747/2005.7586538.bard.

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The objectives of the BARD proposal were to determine the mechanisms of nonspecific cytotoxic cells (NCC) that are necessary to provide heightened innate resistance to infection and to identify the antigenic determinants in Streptococcus iniae that are best suited for vaccine development. Our central hypothesis was that anti-bacterial immunity in trout and tilapia can only be acquired by combining "innate" NCC responses with antibody responses to polysaccharide antigens. These Objectives were accomplished by experiments delineated by the following Specific Aims: Specific aim (SA) #1 (USA) "Clone and Identify the Apoptosis Regulatory Genes in NCC"; Specific aim #2 (USA)"Identify Regulatory Factors that Control NCC Responses to S. iniae"; Specific aim #3 (Israel) "Characterize the Biological Properties of the S. iniae Capsular Polysaccharide"; and Specific aim #4 (Israel) "Development of an Acellular Vaccine". Our model of S. iniae pathogenesis encompassed two approaches, identify apoptosis regulatory genes and proteins in tilapia that affected NCC activities (USA group) and determine the participation of S.iniae capsular polysaccharides as potential immunogens for the development of an acellular vaccine (Israel group). We previously established that it was possible to immunize tilapia and trout against experimental S. difficile/iniaeinfections. However these studies indicated that antibody responses in protected fish were short lived (3-4 months). Thus available vaccines were useful for short-term protection only. To address the issues of regulation of pathogenesis and immunogens of S. iniae, we have emphasized the role of the innate immune response regarding activation of NCC and mechanisms of invasiveness. Considerable progress was made toward accomplishing SA #1. We have cloned the cDNA of the following tilapia genes: cellular apoptosis susceptibility (CAS/AF547173»; tumor necrosis factor alpha (TNF / A Y 428948); and nascent polypeptide-associated complex alpha polypeptide (NACA/ A Y168640). Similar attempts were made to sequence the tilapia FasLgene/cDNA, however these experiments were not successful. Aim #2 was to "Identify Regulatory Factors that Control NCC Responses to S. iniae." To accomplish this, a new membrane receptor has been identified that may control innate responses (including apoptosis) of NCC to S. iniae. The receptor is a membrane protein on teleost NCC. This protein (NCC cationic antimicrobial protein-1/ncamp-1/AAQ99138) has been sequenced and the cDNA cloned (A Y324398). In recombinant form, ncamp-l kills S. iniae in vitro. Specific aim 3 ("Characterize the Biological Properties of the S.iniae Capsular Polysaccharide") utilized an in- vitro model using rainbow trout primary skin epithelial cell mono layers. These experiments demonstrated colonization into epithelial cells followed by a rapid decline of viable intracellular bacteria and translocation out of the cell. This pathogenesis model suggested that the bacterium escapes the endosome and translocates through the rainbow trout skin barrier to further invade and infect the host. Specific aim #4 ("Development of an Acellular Vaccine") was not specifically addressed. These studies demonstrated that several different apoptotic regulatory genes/proteins are expressed by tilapia NCC. These are the first studies demonstrating that such factors exist in tilapia. Because tilapia NCC bind to and are activated by S. iniae bacterial DNA, we predict that the apoptotic regulatory activity of S. iniae previously demonstrated by our group may be associated with innate antibacterial responses in tilapia.
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Neyra, Joan M. Nasal Colonization with Methicillin-Resistant Staphylococcus aureus in Military Personnel in a Developing Country - Development of a Skin and Soft Tissue Infection Surveillance System in the Peruvian Air Force. Defense Technical Information Center, 2015. http://dx.doi.org/10.21236/ad1012737.

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Noga, Edward J., Angelo Colorni, Michael G. Levy, and Ramy Avtalion. Importance of Endobiotics in Defense against Protozoan Ectoparasites of Fish. United States Department of Agriculture, 2003. http://dx.doi.org/10.32747/2003.7586463.bard.

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Infectious disease is one of the most serious causes of economic loss in all sectors of aquaculture. There is a critical need to understand the molecular basis for protection against infectious disease so that safer, more reliable and more cost-effective strategies can be designed for their control. As part of this effort, the major goal of our BARD project was to determine the importance of endobiotics as a defense against protozoan ectoparasites in fish. Endobiotics, or antimicrobial polypeptides, are peptides and small proteins that are increasingly recognized as having a vital role in the innate defense of virtually all animals. One objective of our BARD project was to determine the antiparasitic potency of one specific group of endobiotics that were isolated from hybrid striped bass (Morone saxatilis x M chrysops). We found that these endobiotics, which we had previously named histone-like proteins (HLPs), exhibited potent activity against Amyloodinium and that the putative levels of HLPs in the skin were well within the levels that we found to be lethal to the parasite in vitro. We also found evidence for the presence of similar antibiotics in sea bream (Sparus aurata) and Mediterranean sea bass (Dicentrarchus labrax). We also examined the effect of chronic stress on the expression of HLP in fish and found that HLP levels were dramatically decreased after only one week of a crowding/high ammonia sublethal stress. We also began to explore the feasibility of upregulating endobiotics via immunostimulation. However, we did not pursue this objective as fully as we originally intended because we spent a much larger effort than originally anticipated on the last objective, the attempted isolation of novel endobiotics from hybrid striped bass. In this regard, we purified and identified four new peptide endobiotics. These endobiotics, which we have named piscidins (from "Pisces" meaning fish), have potent, broad-spectrum activity against a number of both fish and human pathogens. This includes not only parasites but also bacteria. We also demonstrated that these peptides are present in the mast cell. This was the first time that the mast cell, the most common tissue granulocyte in vertebrates, was shown to possess any type of endobiotic. This finding has important implications in explaining the possible function of mast cells in the immune response of vertebrates. In summary, the research we have accomplished in this BARD project has demonstrated that endobiotics in fish have potent activity against many serious pathogens in aquaculture and that there is considerable potential to use these compounds as stress indicators in aquaculture. There is also considerable potential to use some of these compounds in other areas of medicine, including treatment of serious infectious diseases of humans and animals.
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