Relevant bibliographies by topics / Skin irritation study

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Academic literature on the topic 'Skin irritation study'

Author: Grafiati
Published: 5 June 2025
Last updated: 2 August 2025

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Journal articles on the topic "Skin irritation study"

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Draelos, Zoe, Emil Tanghetti, Linda Stein Gold, et al. "Dermal Irritation, Sensitization, and Safety of Fixed-Dose Triple-Combination Clindamycin Phosphate 1.2%/Benzoyl Peroxide 3.1%/Adapalene 0.15% Gel in Healthy Participants." SKIN The Journal of Cutaneous Medicine 7, no. 4 (2023): s227. http://dx.doi.org/10.25251/skin.7.supp.227.

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Introduction: IDP-126 polymeric mesh gel (clindamycin phosphate 1.2%/benzoyl peroxide [BPO] 3.1%/adapalene 0.15%) is the first triple-combination, fixed-dose topical acne product in development and it addresses major acne pathophysiological processes. IDP-126 demonstrated superior efficacy to vehicle and component dyads, with good safety/tolerability in a phase 2 study of participants with moderate-to-severe acne. The objectives of this study were to assess dermal irritation/sensitization and safety of IDP-126 gel in two phase 1 studies and to compare irritancy of IDP-126 gel and commercially
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Kandárová, Helena, Patrick Hayden, Erin Spiller, Mitch Klausner, Joseph Kubilus, and John Sheasgreen. "In vitro skin irritation test: Increasing the sensitivity of the EpiDerm skin irritation protocol evaluated in the ECVAM skin irritation validation study." Toxicology Letters 172 (October 2007): S81. http://dx.doi.org/10.1016/j.toxlet.2007.05.230.

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Amasa, Wayessa, Dante Santiago, Seblework Mekonen, and Argaw Ambelu. "Are Cosmetics Used in Developing Countries Safe? Use and Dermal Irritation of Body Care Products in Jimma Town, Southwestern Ethiopia." Journal of Toxicology 2012 (2012): 1–8. http://dx.doi.org/10.1155/2012/204830.

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Background. Rabbit skin model was used to test skin irritation of the most commonly used cosmetic products in Jimma town, southwestern Ethiopia. The most commonly used cosmetics were Dove, Glysolid, College, Top Society, Fair and Lovely, Nivea, Lux, Magic fruit world, Solea, Body talk, Kris, Holly, Victoria, and Sweet Heart.Methods. Intact and abraded rabbit skins were tested for erythema and edema under shade and under sun exposure. Draize Primary Irritation Index (PII) was used to calculate skin irritation of each cosmetic. Cosmetic ingredients were analyzed from the labels.Results and Discu
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H.I., Muhammad Aiman, S. P. Koh, Y. S. Sew, et al. "Anti-inflammatory efficacy and skin irritation study of Cleome gynandra extract: an animal model and pre-clinical evaluation." Food Research 8, Supplementary 3 (2024): 92–103. http://dx.doi.org/10.26656/fr.2017.8(s3).14.

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Cleome gynandra, a kind of medicinal herb which has strong antioxidant properties has been traditionally used for treating various ailments including skin inflammatory diseases. To date, the anti-inflammatory efficacy of C. gynandra based cream has not been reported. The aim of the study was to evaluate the anti-inflammatory activities of C. gynandra leaf extract cream using an in vivo arachidonic acid-induced ear edema in the rat model. The expression of genes related to rat ear inflammation was measured to evaluate the topical anti-inflammatory activity of C. gynandra cream. The toxicity eff
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Rahmi, Dwinna, Retno Yunilawati, Bumiarto Nugroho Jati, et al. "Antiaging and Skin Irritation Potential of Four Main Indonesian Essential Oils." Cosmetics 8, no. 4 (2021): 94. http://dx.doi.org/10.3390/cosmetics8040094.

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Essential oils possess antiaging properties due to their antioxidant activity. This study aims to determine the antiaging activities of four main Indonesian essential oils and their irritation potential on the skin. The spot yeast and in vivo rat skin with UVB exposure methods were used to analyze the antiaging activity of essential oils on aging triggered by endogenous and exogenous factors, respectively. Meanwhile, patch tests and clinical evaluations were used for the skin irritation potential analysis. The antiaging activity results from the endogenous factor showed that the use of clove,
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Bajaj, Himani, Mayank Yadav, Seema B. Chauhan, et al. "ACECLOFENAC LOADED FILM FORMING GELS: IN VIVO STUDY." Indian Drugs 60, no. 06 (2023): 90–93. http://dx.doi.org/10.53879/id.60.06.13865.

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For arthritis, there is need of development of a drug delivery system which permits less frequent dosing by maintaining a close contact with the skin for prolonged time period, thereby improving the patient compliance, especially among elderly. Till date, film forming gels of aceclofenac for arthritis are not available in the market. It is a novel approach which can be used as an alternative to conventional topical and transdermal formulations to treat arthritis. Therefore, HPMC and Eudragit RL 100 based film forming gels of aceclofenac were prepared. On the basis of in vitro potential, the fo
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Rahmi, Dwinna, Retno Yunilawati, Ira Setiawati, et al. "ANTIOXIDANT ACTIVITY, SKIN IRRITAION POTENTIAL AND CHEMICAL COMPOSITION OF CLOVE LEAF OIL FROM WEST JAVA INDONESIA." Jurnal Sains Materi Indonesia 23, no. 1 (2021): 24. http://dx.doi.org/10.17146/jsmi.2021.23.1.6398.

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ANTIOXIDANT ACTIVITY, SKIN IRRITATON POTENTIAL, AND CHEMICAL COMPOSITION OF CLOVE LEAF OIL FROM WEST JAVA INDONESIA. Essential oils with specific chemical compositions have the potential as a source of antioxidants in cosmetics, however, in general, essential oils are not safe because of the potential for skin irritation. This study aims is to perform fractionation to obtain clove oil with a chemical composition that is safe on the skin and does not reduce its antioxidant activity. Fractionation was performed at a temperature of 100 – 285 oC. Chemical composition was determined by Mass Chromat
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Ghazali, Ahmad Rohi, Nor Fadilah Rajab, Muhammad Firas Zainuddin, and Nazeha Ahmat. "Assessment of Skin Irritation and Sensitisation Effects by Topical Pterostilbene." Biomedical and Pharmacology Journal 14, no. 4 (2021): 1917–27. http://dx.doi.org/10.13005/bpj/2290.

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Pterostilbene has dermal medicinal benefits such as anti-inflammatory, antioxidative effects and photoprotective properties against UVB radiation. The purpose of this study was to evaluate the dermal toxicity of pterostilbene via skin irritation and sensitisation. A skin irritation test was done according to the Organization Economic Co-operation and Development 404 guideline with the scoring of irritation based on erythema and oedema in 5 albino rabbits were observed up to 14 days. The sensitisation test using the Buehler Test in accordance with the ISO 10993-10 guideline was used to study th
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BOTHAM, P. "Outcome of the ECVAM skin irritation validation study." Toxicology 231, no. 2-3 (2007): 98–99. http://dx.doi.org/10.1016/j.tox.2006.11.021.

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Bujak, Tomasz, Tomasz Wasilewski, and Zofia Nizioł-Łukaszewska. "Effect of molecular weight of polyvinylpyrrolidone on the skin irritation potential and properties of body wash cosmetics in the coacervate form." Pure and Applied Chemistry 91, no. 9 (2019): 1521–32. http://dx.doi.org/10.1515/pac-2018-0703.

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Abstract Body wash cosmetics are among the most common groups of cosmetics used by consumers. Faced with strong competition in the marketplace, cosmetic manufacturers search for innovative solutions both in terms of product composition and form. An example of an innovative technology which can be used in the production of body wash cosmetics is the process of coacervation which yields a concentrated body wash product. Another important aspect which needs to be considered in the formulation of body wash cosmetics is their safety of use. It is crucial to ensure that such cosmetic products do not
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Book chapters on the topic "Skin irritation study"

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Osei-Owusu, Yaw, Raymond Owusu-Achiaw, Paa Kofi Osei-Owusu, and Julia Atayi. "Reducing Commodity-Driven Biodiversity Loss: The Case of Pesticide Use and Impacts on Socio-Ecological Production Landscapes (SEPLs) in Ghana." In Biodiversity-Health-Sustainability Nexus in Socio-Ecological Production Landscapes and Seascapes (SEPLS). Springer Nature Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-9893-4_12.

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AbstractGhana’s Western North and Central Regions are biodiversity-rich landscapes. Cocoa is a major commodity produced in these two regions, accounting for over 50% of Ghana’s cocoa output. As part of the efforts to further improve productivity and ecological health of the landscape, the Government of Ghana initiated the Cocoa Disease and Pests Control Programme primarily to control cocoa pests and diseases, including the use of pesticides. In recent times, however, there has been an upsurge in the use of highly hazardous pesticides (HHPs) that have far-reaching consequences on human and ecol
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Dias André, Fisterer Bernhard, Lamla Gregor, Kuhn Klaus, Hartvigsen Gunnar, and Horsch Alexander. "Measuring Physical Activity with Sensors: A Qualitative Study." In Studies in Health Technology and Informatics. IOS Press, 2009. https://doi.org/10.3233/978-1-60750-044-5-475.

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Long term wearing of motion and heart rate sensors are essential aspects for longitudinal studies on physical activity measurement studies. We conducted a qualitative study with seven subjects in a total of 13 test sessions to identify usability and handling problems associated with Stayhealth RT3, Actigraph GT1M and Polar RS800 sensors. We found that battery life limitation is the most recurrent technical problem and long term wear of heart rate sensors produces discomfort and skin irritation.
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Misar, K. S., P. T. Khachane, M. H. Taywade, M. R. Raut, and W. B. Gurnule. "FORMULATION, DEVELOPMENT AND EVALUATION OF NAIL PAINT REMOVER CREAM." In Futuristic Trends in Chemical Material Sciences & Nano Technology Volume 3 Book 18. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3bdcs18ch17.

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Nail paint remover plays a significant role in personal grooming products and it is commonly used for removal of nail paints from the surface of nails. However, these products often contain harsh chemicals that can lead to nail dryness, irritation and lingering odour. It is reported that, Dibutyl Adipate is often employed as a plasticizer, a colourless, odourless,clear liquid having good solvency, moisturizing effect and skin conditioning property. Hence, in this research study, we propose the formulation, development and evaluation of nail paint remover cream, having gentle nail paint removin
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Rana, Amrita, Sindhu Abraham, Sharon Furtado, K. Megha, and J. Anbu. "In Vivo Skin Irritation Potential of a Topical Gel Loaded with Tea Tree Oil Nanosponges." In Current Trends in Drug Discovery, Development and Delivery (CTD4-2022). Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671090-00387.

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Tea tree oil is the most sought-after natural oil because of its diverse pharmacological actions. It is widely used as a superficial antiseptic because of its broad-spectrum antimicrobial action. However, the oil is volatile and direct application on the skin can cause severe erythema. The present work aims to overcome this issue by developing topical gels loaded with tea tree oil nanosponges. Tea tree oil was encapsulated into nanosponges by emulsion solvent evaporation using varying concentrations of polyvinyl alcohol and ethyl cellulose. The nanosponges formed were subsequently characterize
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Sruthy, Keerthy. "18 HERBS ORGANICS - STRESS RELIEF OIL – ASUVAGENTHI BALALAKSHATHI THAILAM." In Futuristic Trends in Medical Sciences Volume 3 Book 6. Iterative International Publisher, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3bbms6p5ch3.

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We hereby attest to the authenticity of the study and guarantee that the data is accurate to the best of our knowledge. We also attest that the study was conducted in full compliance with BIS Specification, IS 4011:2018 Methods of test for safety evaluation of cosmetics, reaffirmed (2004), Edition 3.2 (2007-11), second revision (ICS 7 1.1 00.40), clause 4.3.1, 4.3.1.2 BIS 2008. Skin Irritation Test On human subjects, guidelines, and regulations of the Independent Scientific and Ethics Committee for the Purpose of control and supervision of experiments and on getting approval of the sponsor. Th
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Siqueira, Maria Clara Teixeira, Mariana Alves Gama Souza da Silva, Carolina Teixeira Nogueira, Maria de Lourdes Ferreira Medeiros de Matos, Alcemar Antônio Lopes de Matos, and Fernando Basílio dos Santos. "Coronary syndromes associated with COVID-19: A literature review." In Health of Tomorrow: Innovations and Academic Research. Seven Editora, 2024. http://dx.doi.org/10.56238/sevened2023.007-090.

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In January 2020, the World Health Organization (WHO) declared a state of Public Health Emergency of International Concern. The rapid population illness and the increase in the number of deaths from unknown causes generated a social panic. In view of this, it was understood that the broad spectrum of symptoms related to the respiratory infection of SARS-CoV-2 has a direct impact on the cardiovascular and immune systems and can cause conditions both in the acute phase of the infection and in a later phase. This study was developed from a meticulous and integrated review of the literature in rece
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Conference papers on the topic "Skin irritation study"

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Zhao, Nan-Xi, Xi-Bin Wang, Man-Li Wang, et al. "Experimental Study on the Irritation of Granisetron Patch to Rabbit Skin." In 2015 International Conference on Medicine and Biopharmaceutical. WORLD SCIENTIFIC, 2016. http://dx.doi.org/10.1142/9789814719810_0126.

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Ma, Zhenzhen, Xuhui Zhang, Shaojun Hao, et al. "Experimental study on skin irritation of bone spur powder on rabbit." In 2017 INTERNATIONAL CONFERENCE ON BIOTECHNOLOGY AND BIOENGINEERING (ICBB-2017). Author(s), 2018. http://dx.doi.org/10.1063/1.5034279.

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Yu, Jin-Woo, Bomin Kim, Jinmo Kim, Han-Joon Kim, and Ji-Woong Choi. "A Study on Reducing Skin Irritation in Multi-Channel TES for Painless Force Feedback." In 2023 Fourteenth International Conference on Ubiquitous and Future Networks (ICUFN). IEEE, 2023. http://dx.doi.org/10.1109/icufn57995.2023.10201126.

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Sabbagh, Marwan, Philip Mathew, and Alan Blau. "A Randomized Double-Blind Study to Assess the Skin Irritation and Sensitization Potential of Once-Weekly Donepezil Transdermal Delivery System (P8-6.009)." In 2023 Annual Meeting Abstracts. Lippincott Williams & Wilkins, 2023. http://dx.doi.org/10.1212/wnl.0000000000203521.

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Tan, Emily, Krassimir Danov, Rumyana Stanimirova, et al. "Clear and Transparent Methyl Ester Sulphonate Micellar Systems for Mild Hair Shampoo Applications." In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/rblw7888.

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"Methyl ester sulphonates (MES), which are produced from renewable vegetable oil-based materials and have an ISO 16128 natural origin index of 0.84, are promising new surfactants for conditioning hair shampoos. Previous studies have shown that MES has low skin irritation potential (i.e., mild to the skin), provides easier deposition of conditioning agents compared to sodium lauryl ether sulphate (SLES), and readily delivers desired rheology profiles. A drawback of MES is that it has poor solubility at low temperatures. The Krafft temperatures (TK) of MES-C16 and MES-C18 are 28 °C and 41 °C, re
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LV, WEN-TAO, CHENG-HUI ZHU, XIANG-WEN MENG, and HUI ZHI. "THE EXPERIMENTAL STUDY OF CUPPING THERAPY INTERVENING THE RABBIT MODEL OF COLD STAGNATION LEADING TO BLOOD STASIS SYNDROME BASED ON THE BIOCHEMICAL CRITERION." In 2021 International Conference on Education, Humanity and Language, Art. Destech Publications, Inc., 2021. http://dx.doi.org/10.12783/dtssehs/ehla2021/35719.

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Objective: Explore the partial mechanisms of cupping therapy by means of the cellular factors in the peripheral blood cells; methods: Replicate the rabbit model of cold stagnation leading to blood stasis by adopting the cold stimulation and randomly dividing 12 rabbits to three groups based on the weight. Observe the sign of the rabbits before and after cupping test, the content of the vascular endothelial growth factor (VEGF), epidermal growth factor (EGF)in the peripheral blood; Results: After replicated the model, the model group and the treatment group gradually appeared the sign of cold s
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Ahmed, Sangar, and Muzhda Qader. "Household Cleaning Effect on Women's Health: A Potentially Important Public Health Concern." In 4th Scientific Conference on Women’s Health. Hawler Medical University, 2025. https://doi.org/10.15218/crewh.2024.01.

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Background and Objective: Household cleaning products are widely used to maintain hygiene and sanitation; however, their frequent use has been linked to various health risks. Women, particularly those who are married, aged 18–32, and hold a BSc degree, have been identified as a demographic with higher exposure rates to these products. The chemicals present in household cleaners may contribute to respiratory issues, skin conditions, and other adverse health effects. This study aimed to investigate the health implications associated with household cleaner use among women. The findings are expect
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Caprini, J. A., J. C. Kudrna, and A. S. Mitchell. "THROMBOSIS PROPHYLAXIS IN TOTAL HIP ARTHROPLASTY PATIENTS USING A COMBINATION OF PHYSICAL METHODS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644209.

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Lowering the incidence of thromboembolic events in patients undergoing total hip arthroplasty remains a high priority and various drug and physical method protocols have been devised to achieve this goal. We report here our experience using full-length antiembolism stockings (TED), full-length sequential compression devices (SCD) and the continuous passive motion device (CPM) to prevent thrombosis in patients undergoing total hip procedures. 106 consecutive patients were enrolled in this protocol, including 80 primary and 26 revision hip arthroplasties. Cement was used in 40 primary and 12 rev
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Alves, Adrielly, and Régis Casimiro Leal. "Theoretical study of the mechanism of chromogenic chemodosimeters in the detection of sulfhydryl (SH–) and hydroxyl (OH–) anions." In VIII Simpósio de Estrutura Eletrônica e Dinâmica Molecular. Universidade de Brasília, 2020. http://dx.doi.org/10.21826/viiiseedmol2020128.

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Sulfide (S2−) is a biologically and environmentally important anion. Exposure to the sulfide anion can cause chronic, respiratory diseases and irritations in the skin and mucous membranes. The protonated HS− or H2S forms are more toxic than the S2− itself. A derivative of the family of 2,4,6-triaryl-pyrylium cations bearing an amine in the para position of the 4-aryl group is sensitive for detecting sulfide anions in solution. Through DFT calculations, performed at level B3LYP/6-31+G(d) in gas phase, these authors present the thermodynamic stability of the interaction of chemodosimeters derive
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Carvalho, Cristina, Carla Costa Pereira, Gianni Montagna, and Carlos Manuel Figueiredo. "Biodyes: a new approach in textile dyeing and printing technological processes." In 14th International Conference on Applied Human Factors and Ergonomics (AHFE 2023). AHFE International, 2023. http://dx.doi.org/10.54941/ahfe1003641.

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The textile industry is responsible for the production of more than 2 billion tons of effluents/waste, most of which are discarded into the ecosystem, namely and mostly into water ecosystems, essentially after the dyeing and printing processes. In fact, dyeing is one of the most polluting processes in the textile industry, representing a high source of pollution. According to the World Bank, the textile dyeing industries are responsible for more than 20% of the pollution of all water used at the industrial level.One of the serious problems related to the group of synthetic dyes is the level of
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Reports on the topic "Skin irritation study"

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Gunasekar, P. G., J. N. McDougal, J. V. Rogers, C. M. Garrett, M. B. Kabbur, and W. W. Brinkely. Comparative Study of Molecular Mechanisms of Skin Irritation After Acute Exposure to m-XYLENE in Rats and Guinea Pigs. Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada453214.

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