Academic literature on the topic 'Skin irritation test'

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Journal articles on the topic "Skin irritation test"

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Bunga Eloystina, Laurencia Julia, Silvy Aldila, Valentina Girsang, and Anifatus Sa'adah. "Irritation Test of Optimum Preparation of Celery Extract Face Clay Cleanser With Sodium Lauryl Sulfate (SLS) and Cocamidopropyl Betaine (CAPB) as Surfactants." Science and Community Pharmacy Journal 3, no. 2 (2024): 211–16. https://doi.org/10.63520/scpj.v3i2.580.

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Surfactant is one of the important things in making face clay cleanser preparations. Sodium Lauryl Sulfate (SLS) is an anionic type surfactant that is often used in cosmetic products. The use of Sodium Lauryl Sulfate (SLS) can cause irritation and dry skin. Combination with cocamidopropyl betaine (CAPB) which is amophoteric can reduce skin irritation. Based on this, a safety test is needed which aims to meet the preparation requirements before being marketed to the wider community. One of the safety tests that can be done is the skin irritation test. The test method used is the human patch tes
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Deswani, Deswani, Sri Djuwitaningsih, Harpolia Cartika, and Paul Malau. "Irritation Test of Cream Preparations Made from Purple Cabbage Extract Against Healthy Skin Using The Path Test Method." JURNAL INFO KESEHATAN 23, no. 1 (2025): 1–9. https://doi.org/10.31965/infokes.vol23.iss1.1458.

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Testing for skin irritation caused by new substances is a critical component of safety evaluation procedures. Pharmaceutical formulations and active ingredients intended for topical application have the potential to cause skin irritation, necessitating thorough safety assessments prior to public distribution. This study aimed to evaluate the primary irritation potential of a purple cabbage extract cream using the patch test method on healthy older adults. The experimental research involved 18 volunteers, who were administered 0.625% purple cabbage extract cream and a placebo preparation withou
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Deswani, Deswani, Sri Djuwitaningsih, and Harpolia Cartika. "Irritation Test of Cream Preparations Made from Purple Cabbage Extract Against Healthy Skin Using The Path Test Method." JURNAL INFO KESEHATAN 22, no. 4 (2024): 858–66. https://doi.org/10.31965/infokes.vol22.iss4.1458.

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Testing for skin irritation caused by new substances is a critical component of safety evaluation procedures. Pharmaceutical formulations and active ingredients intended for topical application have the potential to cause skin irritation, necessitating thorough safety assessments prior to public distribution. This study aimed to evaluate the primary irritation potential of a purple cabbage extract cream using the patch test method on healthy older adults. The experimental research involved 18 volunteers, who were administered 0.625% purple cabbage extract cream and a placebo preparation withou
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Kandárová, Helena, Patrick Hayden, Erin Spiller, Mitch Klausner, Joseph Kubilus, and John Sheasgreen. "In vitro skin irritation test: Increasing the sensitivity of the EpiDerm skin irritation protocol evaluated in the ECVAM skin irritation validation study." Toxicology Letters 172 (October 2007): S81. http://dx.doi.org/10.1016/j.toxlet.2007.05.230.

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Draelos, Zoe, Emil Tanghetti, Linda Stein Gold, et al. "Dermal Irritation, Sensitization, and Safety of Fixed-Dose Triple-Combination Clindamycin Phosphate 1.2%/Benzoyl Peroxide 3.1%/Adapalene 0.15% Gel in Healthy Participants." SKIN The Journal of Cutaneous Medicine 7, no. 4 (2023): s227. http://dx.doi.org/10.25251/skin.7.supp.227.

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Introduction: IDP-126 polymeric mesh gel (clindamycin phosphate 1.2%/benzoyl peroxide [BPO] 3.1%/adapalene 0.15%) is the first triple-combination, fixed-dose topical acne product in development and it addresses major acne pathophysiological processes. IDP-126 demonstrated superior efficacy to vehicle and component dyads, with good safety/tolerability in a phase 2 study of participants with moderate-to-severe acne. The objectives of this study were to assess dermal irritation/sensitization and safety of IDP-126 gel in two phase 1 studies and to compare irritancy of IDP-126 gel and commercially
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Amasa, Wayessa, Dante Santiago, Seblework Mekonen, and Argaw Ambelu. "Are Cosmetics Used in Developing Countries Safe? Use and Dermal Irritation of Body Care Products in Jimma Town, Southwestern Ethiopia." Journal of Toxicology 2012 (2012): 1–8. http://dx.doi.org/10.1155/2012/204830.

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Background. Rabbit skin model was used to test skin irritation of the most commonly used cosmetic products in Jimma town, southwestern Ethiopia. The most commonly used cosmetics were Dove, Glysolid, College, Top Society, Fair and Lovely, Nivea, Lux, Magic fruit world, Solea, Body talk, Kris, Holly, Victoria, and Sweet Heart.Methods. Intact and abraded rabbit skins were tested for erythema and edema under shade and under sun exposure. Draize Primary Irritation Index (PII) was used to calculate skin irritation of each cosmetic. Cosmetic ingredients were analyzed from the labels.Results and Discu
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Suhendriyo, Suhendriyo, Dwi Astuti Handayani, and Susilo Yulianto. "Test Physical and Test Irritation Provision Cream Extract Aromatic Ginger ( Kaempferia Galanga L.)." ULIL ALBAB : Jurnal Ilmiah Multidisiplin 4, no. 4 (2025): 1192–99. https://doi.org/10.56799/jim.v4i4.8232.

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Galangal rhizome is used in traditional medicine which has effectiveness as an anti-inflammatory and antitoxin. Galangal rhizome contains flavonoids, polyphenols, saponins, essential oils. The content of polyphenols in the form of ethylcinnamate can provide anti-inflammatory effects. The content of saponins, flavonoids, essential oils in galangal rhizome as a treatment for mycosis. The purpose of this study was to determine the results of physical tests and irritation tests of galangal extract cream preparations including organoleptic tests, homogeneity tests, spreadability tests, adhesion tes
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Banerjee, Subham, Pronobesh Chattopadhyay, Animesh Ghosh, Manash Pratim Pathak, Shweta Singh, and Vijay Veer. "Acute Dermal Irritation, Sensitization, and Acute Toxicity Studies of a Transdermal Patch for Prophylaxis Against (±) Anatoxin-A Poisoning." International Journal of Toxicology 32, no. 4 (2013): 308–13. http://dx.doi.org/10.1177/1091581813489996.

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The skin irritating, sensitizing, and acute dermal toxicity potential of a novel combinational prophylactic transdermal patch, mainly composed of eserine and pralidoxime chloride as active pharmaceutical ingredients, against (±) anatoxin-a poisoning were investigated in rabbits, guinea pigs, and rats in compliance with the Organisation for Economic Cooperation and Development guidelines. In primary skin irritation test, rabbits were dermally attached with the therapeutically active transdermal patch or with a placebo patch for 72 hours. The transdermal patches did not induce any adverse reacti
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Basketter, David, Dagmar Jírova, and Helena Kandárová. "Review of skin irritation/corrosion hazards on the basis of human data: a regulatory perspective." Interdisciplinary Toxicology 5, no. 2 (2012): 98–104. http://dx.doi.org/10.2478/v10102-012-0017-2.

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Abstract Regulatory classification of skin irritation has historically been based on rabbit data, however current toxicology processes are transitioning to in vitro alternatives. The in vitro assays have to provide sufficient level of sensitivity as well as specificity to be accepted as replacement methods for the existing in vivo assays. This is usually achieved by comparing the in vitro results to classifications obtained in animals. Significant drawback of this approach is that neither in vivo nor in vitro methods are calibrated against human hazard data and results obtained in these assays
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Gfeller, W., W. Kobel, and G. Seifert. "Overview of animal test methods for skin irritation." Food and Chemical Toxicology 23, no. 2 (1985): 165–68. http://dx.doi.org/10.1016/0278-6915(85)90009-2.

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Dissertations / Theses on the topic "Skin irritation test"

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Bertaux, Emilie. "Mechanical friction between skin and sport textiles yielding skin irritation." Valenciennes, 2008. https://ged.uphf.fr/nuxeo/site/esupversions/808ac959-0f92-473f-b3bb-2a0acab897a8.

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Afin d'améliorer le confort des coureurs en réduisant l'irritation de la peau due au phénomène de friction mécanique, le Textile Friction Analyzer a été récemment développé au sein de l'Empa. Cet appareillage permet de caractériser la friction peau-textile (T-shirt et chaussette) en utilisant une peau artificielle (skin model) et ceci en simulant les conditions de contacts durant la pratique sportive. Différentes peaux artificielles ont été développées afin de reproduire les propriétés frictionnelles de la peau du pied ou du téton humain. Les paramètres de tests comme la force de contact, la v
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Manche, Monique. "Etude de la toxicité cutanée et respiratoire des alcools dans les produits hydro-alcooliques d’hygiène des mains." Thesis, Lille 2, 2017. http://www.theses.fr/2017LIL2S038/document.

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L’hygiène des mains (HDM) est déterminante dans la prévention du risque infectieux associé aux soins. Les pratiques actuelles privilégient l’utilisation de produits hydro-alcooliques (PHA), généralement formulés avec de l’éthanol, de l’isopropanol et/ou du n-propanol, en présence de co-formulants pour une meilleure acceptabilité cutanée. L’efficacité antimicrobienne sur un temps court, nécessaire en raison des situations fréquentes de pratique d’HDM, est atteinte par des teneurs élevées en alcools pouvant excéder 80 % p/p. Cela soulève la question de la toxicité cutanée et respiratoire associé
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Books on the topic "Skin irritation test"

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A, Soemardji Andreanus, ed. Pengembangan bentuk dan stabilitas fisik serta uji iritasi kulit dari sediaan kulit obat tradisional/jamu produksi P.J. "Alam Subur Manjur", Tasikmalaya =: Development of formulation and physical stability of traditional skin preparation "Alam Subur Manjur", Tasikmalaya's product and its skin irritation test. Jurusan Farmasi FMIPA-ITB], 1996.

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Test No. 439: In Vitro Skin Irritation. OECD, 2010. http://dx.doi.org/10.1787/9789264090958-en.

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Test No. 439: In Vitro Skin Irritation: Reconstructed Human Epidermis Test Method. OECD, 2020. http://dx.doi.org/10.1787/9789264242845-en.

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Test No. 439: In Vitro Skin Irritation - Reconstructed Human Epidermis Test Method. OECD, 2013. http://dx.doi.org/10.1787/9789264203884-en.

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AUTHOR_ID, NULL. Test No. 439 : In Vitro Skin Irritation: Reconstructed Human Epidermis Test Method. OECD, 2021.

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Sherman, Kerry A., and Laura-Kate E. Shaw. Body Image and the Cancer Treatment Trajectory. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190655617.003.0006.

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Abstract: The chapter “Body Image and the Cancer Treatment Trajectory” provides an overview of body image–related concerns and challenges that can arise throughout the cancer journey, from cancer detection and diagnosis through to active treatment and cancer survivorship. The chapter examines how body image concerns can serve as a significant barrier to cancer detection, including self- and physician examination, routine screening, and diagnostic tests. It then reviews the impact of cancer surgery and treatment-related side effects (such as physical disfigurement, hair loss, skin irritations,
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Book chapters on the topic "Skin irritation test"

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Engelking, Oliver, Horst W. Fuchs, and Dirk Weisensee. "The epiCS® Skin Irritation Test (SIT) Method." In Alternatives for Dermal Toxicity Testing. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-50353-0_6.

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Kandarova, Helena, and Manfred Liebsch. "The EpiDerm™ Skin Irritation Test (EpiDerm™ SIT)." In Alternatives for Dermal Toxicity Testing. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-50353-0_3.

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Alépée, Nathalie, Marie Hélène Grandidier, and José Cotovio. "Skin Irritation Hazard of Chemicals Assessed by the EpiSkin™ In Vitro Test Method." In Alternatives for Dermal Toxicity Testing. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-50353-0_2.

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Alépée, Nathalie, Marie Hélène Grandidier, Carine Tornier, and José Cotovio. "An In Vitro Skin Irritation Test Using the SkinEthic™ Reconstructed Human Epidermal (RHE) Model." In Alternatives for Dermal Toxicity Testing. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-50353-0_4.

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Hoh, A., and K. Maier. "Comparative Cytotoxicity Test with Human Keratinocytes, HaCaT Cells, and Skin Fibroblasts to Investigate Skin-Irritating Substances." In Cell and Tissue Culture Models in Dermatological Research. Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-77817-9_38.

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"Primary Skin Irritation Test." In Dictionary of Toxicology. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-99-9283-6_2218.

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Visperas, Cristina Mejia. "Skin Problems." In Skin Theory. NYU Press, 2022. http://dx.doi.org/10.18574/nyu/9781479810772.003.0003.

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Chapter 2 focuses on Albert Kligman’s experiments on skin allergies and skin irritation, showing how black skin formed a screen through which the troubled visualization of pain became inextricable from the construction of racial difference. Kligman sought to develop a new patch-test assay that could better evaluate the harmful potential of common household products, but in these studies, black skin figured as a problematic screen for visualizing injury, thought too hardy to materialize the pain for which scientist sought visual metrics. Now race, an object of experimentation rather than simply
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Maibach, Howard, and Cheryl Levin. "Animal, Human and In Vitro Test Methods for Predicting Skin Irritation." In Dermatotoxicology, Sixth Edition. Informa Healthcare, 2004. http://dx.doi.org/10.1201/9780203426272.ch36.

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"Animal, Human and In Vitro Test Methods for Predicting Skin Irritation." In Dermatotoxicology. CRC Press, 2004. http://dx.doi.org/10.1201/9780203426272-42.

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"Animal, Human, and in Vitro Test Methods for Predicting Skin Irritation." In Dermatotoxicology Methods: The Laboratory Worker’s Vade Mecum, edited by Sunita M. Patil, Esther Patrick, and Howard I. Maibach. CRC Press, 2019. http://dx.doi.org/10.1201/9780429130434-9.

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Conference papers on the topic "Skin irritation test"

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Klotz, A., A. zur Muhlen, and M. Veeger. "184. Testing the Efficacy of Skin Protectants with the Repetitive Irritation Test." In AIHce 2002. AIHA, 2002. http://dx.doi.org/10.3320/1.2766106.

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Jacobs, Fiona, and Carol Treasure. "Development of an in Vitro Test for the Skin Irritation Potential of Mild Surfactants and Its Validation Against Human Patch Testing." In Virtual 2021 AOCS Annual Meeting & Expo. American Oil Chemists’ Society (AOCS), 2021. http://dx.doi.org/10.21748/am21.395.

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LV, WEN-TAO, CHENG-HUI ZHU, XIANG-WEN MENG, and HUI ZHI. "THE EXPERIMENTAL STUDY OF CUPPING THERAPY INTERVENING THE RABBIT MODEL OF COLD STAGNATION LEADING TO BLOOD STASIS SYNDROME BASED ON THE BIOCHEMICAL CRITERION." In 2021 International Conference on Education, Humanity and Language, Art. Destech Publications, Inc., 2021. http://dx.doi.org/10.12783/dtssehs/ehla2021/35719.

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Objective: Explore the partial mechanisms of cupping therapy by means of the cellular factors in the peripheral blood cells; methods: Replicate the rabbit model of cold stagnation leading to blood stasis by adopting the cold stimulation and randomly dividing 12 rabbits to three groups based on the weight. Observe the sign of the rabbits before and after cupping test, the content of the vascular endothelial growth factor (VEGF), epidermal growth factor (EGF)in the peripheral blood; Results: After replicated the model, the model group and the treatment group gradually appeared the sign of cold s
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Leborgne, François, Reon Smits, Maya Gencheva, et al. "The development of a washable and durable smart textile to measure electrodermal activity for early stress recognition." In Intelligent Human Systems Integration (IHSI 2023) Integrating People and Intelligent Systems. AHFE International, 2023. http://dx.doi.org/10.54941/ahfe1002872.

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This paper presents the results of the development of a new sock garment with integrated electrodes for monitoring physiological signals for stress detection in people with intellectual disabilities or dementia. Misunderstood stress-induced behaviours reduce the quality of life of these individuals and complicate caregiver support and treatment, as the correct interpretation of these behaviours. One of the physiological parameters most related to stress is electrodermal activity (EDA). It shows a direct response to the sympathetic nervous system activation ('fight or flight' response) in the f
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Yu, Jin-Woo, Bomin Kim, Jinmo Kim, Han-Joon Kim, and Ji-Woong Choi. "A Study on Reducing Skin Irritation in Multi-Channel TES for Painless Force Feedback." In 2023 Fourteenth International Conference on Ubiquitous and Future Networks (ICUFN). IEEE, 2023. http://dx.doi.org/10.1109/icufn57995.2023.10201126.

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Gabriela Ene, Alexandra, Lucia Secareanu, Ovidiu Iordache, Mirela Blaga, and Cristina Lite. "Characterization Studies of A Commercial Blue Clay For Cosmetic Textiles With Antibacterial Activity." In 14th International Conference on Applied Human Factors and Ergonomics (AHFE 2023). AHFE International, 2023. http://dx.doi.org/10.54941/ahfe1003642.

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Since the beginning of the present century, tests have shown that some types of clay can present antibacterial activity. In addition, the clay considered for pharmaceutical and cosmetic products have been found to be non-toxic and non-irritating materials, therefore, the use of these types of clay for cosmetic and pharmaceutical purposes has increased in recent years. The above being said, different types of clay have been used over time due to their antibacterial properties, but the analytical methods for their characterization are just beginning to develop. This article is part of a study ha
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Reports on the topic "Skin irritation test"

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Voudouris, P., and T. J. Verkleij. In vitro skin irritation test with Amino acid zootechnical mixture using a human skin model. Wageningen Food & Biobased Research, 2022. http://dx.doi.org/10.18174/581504.

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