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Dissertations / Theses on the topic 'Skin scars'

Author: Grafiati
Published: 4 June 2025
Last updated: 1 August 2025

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1

Yip, Christina. "Re-pigmentation of skin following wounding." Thesis, University of Manchester, 2013. https://www.research.manchester.ac.uk/portal/en/theses/repigmentation-of-skin-following-wounding(a2d4efca-4ace-4081-a19c-6a8eb5d8ca28).html.

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Human skin colour has significant aesthetic and cultural implications. Cutaneous injuries can result in dys-pigmented scars which are more noticeable, aesthetically unpleasant, and can lead to patient distress and social isolation. Management of dys-pigmented scars has been challenging with variable success. There is a limited understanding of the timing, progression and mechanisms of skin re-pigmentation following wounding. This thesis is a detailed sequential study, which describes and quantifies scar colour changes in pigs of different pigmented strains.The first result chapter describes th
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2

Suarez, Pozos Edna. "The effect of skin tension on the formation of keloid scars." Thesis, University of Manchester, 2014. https://www.research.manchester.ac.uk/portal/en/theses/the-effect-of-skin-tension-on-the-formation-of-keloid-scars(6762b081-6818-441b-98e6-6a74ae7b50da).html.

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Keloid scars (KS) are a type of abnormal scarring which is unique to humans. They extend beyond the confines of the original wound margins, do not regress over time and invade the surrounding unaffected skin. The mechanisms involved in the formation of KS remain largely unknown. Clinical observation has shown that in areas where increased tension occurs, such as the sternum, there is a greater propensity for developing KS. However, the precise relationship between skin tension and KS development is yet to be identified. In view of this, I hypothesize that skin tension plays a significant role
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3

Adkins, Bethany I. "Skin Story: with critical introduction: “Scars left by the commonplace for women”." Digital Commons @ East Tennessee State University, 2013. https://dc.etsu.edu/honors/110.

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A creative thesis with a story about themes of domestic violence focused particularly on an aspect of rape culture that does not directly involve rape: blamed femaleness. The critical introduction seeks to make this tie explicit to the text of the story.
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4

Mendoza, Garcia Jenifer Guadalupe. "The role of photodynamic therapy in wound healing and scarring in human skin." Thesis, University of Manchester, 2015. https://www.research.manchester.ac.uk/portal/en/theses/the-role-of-photodynamic-therapy-in-wound-healing-and-scarring-in-human-skin(134fe004-9311-4f5d-a0c9-33efe9239960).html.

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The skin acts as a protective barrier, is crucial for thermoregulation and also forms part of the sensory, immunological and endocrine system. Therefore skin preservation is paramount to preserving life. The loss of skin homeostasis, through injury, initiates the wound healing process where the final outcome is the formation of a scar. Scar treatment remains a challenge, despite a plethora of treatments, resulting in a poor outcome and sub-optimal response to existing therapies. Photodynamic therapy (PDT) has been used to treat oncologic conditions affecting the skin. Its action depends on a p
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5

Burkes, Shona A. "Quantitative Multimodal Skin Imaging in Pediatric Health Care: Infantile Hemangiomas and Hypertrophic Burn Scars." University of Cincinnati / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1396532858.

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6

Hollands, Rebecca. "The elemental analysis of hypertrophic scar tissue, skin and silicone gel sheeting using proton induced X-ray emission, Rutherford backscattering and instrumental neutron activation analysis." Thesis, University of Surrey, 1997. http://epubs.surrey.ac.uk/842673/.

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Hypertrophic scars are painful and unsightly scars frequently resulting from dermal trauma and characterised by excessive collagen. The application of silicone gel sheeting is an effective treatment for these scars. Proton Induced X-Ray Emission, Elastic (Non-Rutherford) Backscattering and Instrumental Neutron Activation were used to determine the compositional changes in the silicone gel sheeting and the skin resulting from contact of the gel with scarred and unscarred skin, and found that although in vitro tests on split skin and in vivo tests using unscarred tissue causes the skin to absorb
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7

Mendez, Mendez Juan. "Mechanical properties of single keloid and normal skin fibroblast measured using an atomic force microscope." Thesis, University of Manchester, 2010. https://www.research.manchester.ac.uk/portal/en/theses/mechanical-properties-of-single-keloid-and-normal-skin-fibroblast-measured-using-an-atomic-force-microscope(92b79f2e-412f-4eaf-bea1-73e8c358d952).html.

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The human body consists of a number of very complex, highly specialised organs which perform a variety of functions that are essential to life and health. One of the main functions of the skin, the largest of the human organs, is to maintain the integrity of the body. It does this by acting as a physical barrier, preventing micro-organisms and other potentially harmful substances from entering the body. When the integrity of the skin is damaged through injury, a self-protective mechanism is triggered and the reparative wound healing process begins. Under normal circumstances the wound healing
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8

Wallingford, Sarah. "Investigations into the epidemiology and aetiology of cancers of the skin." Thesis, University of Manchester, 2014. https://www.research.manchester.ac.uk/portal/en/theses/investigations-into-the-epidemiology-and-aetiology-of-cancers-of-the-skin(97008a57-643e-4244-85c1-4e0a753e4d6f).html.

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The cancers of the skin, melanoma and the keratinocyte cancers, basal cell andsquamous cell carcinomas (BCC and SCC), are among the most common cancersin white populations. While ultraviolet radiation (UVR) is their principal cause,links with non-UVR-related factors have also been noted. Ultimately, theinteraction of these elements results in malignancy however, understanding oftheir specific contributions remains incomplete. This thesis reports findings fromsix studies aiming to investigate gaps in current knowledge of the role of UVR andnon-UVR-related risk factors on skin cancer. The papers
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9

Bertheim, Ulf. "Impaired reparative processes in particular related to hyaluronan in various cutaneous disorders : a structural analysis." Doctoral thesis, Umeå : Univ, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-276.

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10

Sobopha, Mgcineni. "Skins, scars, blankets and blood : a pictorial response to the tensions and conflicts that arise from the representation and the practice of Ulwaluko in contemporary South Africa." Master's thesis, University of Cape Town, 2001. http://hdl.handle.net/11427/25960.

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Ulwaluko (the subject of this study) is a Xhosa male initiation or rite of passage normally marked by elaborate ritual ceremonies and authenticated by circumcision. Human longing for ritual is deep, and in our contemporary culture is often frustrated. As an artist working in such an environment, my close association with these 'visible experiences' or contradictions in life has been the source and stimulus of my creative impulse. Ulwaluko is very close to me and an intensely personal aspect of my history and experience. It forms part of my identity and I ascertain very little distance between
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11

Musolas, Juncosa Alberto. "Sistematización del diagnóstico y tratamiento de las retracciones cicatriciales severas en población subsahariana." Doctoral thesis, Universitat Internacional de Catalunya, 2016. http://hdl.handle.net/10803/392645.

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Les retraccions cicatricials severes són una de les causes més freqüents d’inhabilitació funcional a l’Àfrica, tant a nivell laboral com social, i deixen el pacient amb severes limitacions físiques per a la resta de la seva vida. Fins ara no hi ha descrita cap classificació que pugui esser aplicada en zones de baixos recursos i sobre totes las articulacions de un mateix cos humà. Objectius: Hom planteja la hipòtesi principal que és possible de definir un mètode clar, simple i pragmàtic que permeti classificar de manera universal les retraccions cicatricials sobre qualsevol articulació amb ind
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12

van, Hougenhouck-Tulleken George, and Wesley. "Molecular characterisation of the extracellular matrix protein 1 gene in lipoid proteinosis in South Africa." Thesis, 2006. http://hdl.handle.net/10539/1908.

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Faculty of Health Science Degree of Master of Science in Human Genetics 9809684w<br>Lipoid proteinosis (LP) (OMIM 247100) is a rare autosomal recessive disorder that is caused by mutations within the extracellular matrix protein 1 gene (ECM1). The ECM1 gene has been shown to play a role in angiogenesis and connective tissue matrix generation, especially in skin and bone. The role of ECM1 in normal skin development and maintenance is further highlighted by its role in LP and in lichen sclerosis where autoantibodies are raised against ECM1. LP usually presents in the first year of life w
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13

Simões, Sara de Almeida. "Skin mark patterns of bottlenose dolphins (Tursiops truncatus) in the Ría de Arousa, Galicia (Spain)." Master's thesis, 2019. http://hdl.handle.net/10773/27927.

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Cetaceans frequently display skin marks which can be caused by diseases, parasites, and interactions among conspecifics and with human activities. For the present study, we used one year of photo-identification data for resident bottlenose dolphins of the Ría de Arousa (NW Spain). The aims of this study were to assess the types of skin marks found on bottlenose dolphins and compare them between adult males and females. Four body sections (anterior, ventral, central, and posterior) were defined to assess the prevalence, abundance, richness, and distribution of the marks. Boat-based surveys were
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14

Ramoupi, Koketso. "The efficacy of thiosinaminum 1X cream on striae." Thesis, 2012. http://hdl.handle.net/10210/7856.

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M.Tech.<br>Striae are linear scars in the dermis which arise from rapid stretching of the skin over weakened connective tissue (de Angelis & Adatto, 2010). Striae occur when collagen production cannot keep pace with a sudden growth of the underlying tissues. Striae have no medical consequences but are frequently distressing to those afflicted. These disfiguring marks are usually caused by excessive stretching of the skin that may occur with pregnancy, adolescent growth spurts, obesity and weightlifting (Kang & Arbor, 1998). Striae usually appear on the abdomen, thighs, buttocks, breasts and ex
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15

Lorden, Elizabeth R. "Bioengineered Approaches to Prevent Hypertrophic Scar Contraction." Diss., 2016. http://hdl.handle.net/10161/12230.

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<p>Burn injuries in the United States account for over one million hospital admissions per year, with treatment estimated at four billion dollars. Of severe burn patients, 30-90% will develop hypertrophic scars (HSc). Current burn therapies rely upon the use of bioengineered skin equivalents (BSEs), which assist in wound healing but do not prevent HSc. HSc contraction occurs of 6-18 months and results in the formation of a fixed, inelastic skin deformity, with 60% of cases occurring across a joint. HSc contraction is characterized by abnormally high presence of contractile myofibroblasts which
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16

Sydney, Clive. "A histopathological and immunohistochemical evaluation of scar basal cell carcinomas." Thesis, 2006. http://hdl.handle.net/10413/2061.

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Infiltrative morphological mimicry at sites of biopsy-proven nodular basal cell carcinoma has been described. The immunoprofile of scar BCCs (scar BCCs,SBCCs) has not been documented. The aim of this study was to assess the histopathological spectrum, stromal (fibronectin, laminin, actin, desmin and vimentin) response and proliferation (bcl-2, MIB1 and p53) status of SBCCs. Twenty nine BCCs occurring in scars, unrelated to previous malignancy (de novo scar BCCS, DN-SBCCs), 27 BCCs that were incompletely excised and regrew at the same site (regrowth scar BCCs, RG-SBCCs) and 25 BCCs that were co
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17

KANG, MING-HSUAN, and 康明璇. "To Explore The Potential Of Various Types Of Transforming Growth Factor Inhibitors To Prevent Scar Dysplasia In Human Skin Fibroblasts." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/12111055611796941183.

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18

Grant, Colin A., Peter C. Twigg, and Desmond J. Tobin. "Static and dynamic nanomechanical properties of human skin tissue using atomic force microscopy: Effect of scarring in the upper dermis." 2012. http://hdl.handle.net/10454/5495.

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no<br>Following traumatic injury, skin has the capacity to repair itself through a complex cascade of biochemical change. The dermis, which contains a load-bearing collagenous network structure, is remodelled over a long period of time, affecting its mechanical behaviour. This study examines the nanomechanical and viscoelastic properties of the upper dermis from human skin that includes both healthy intact and scarred tissue. Extensive nanoindentation analysis shows that the dermal scar tissue exhibits stiffer behaviour than the healthy intact skin. The scar skin also shows weaker viscoelastic
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