Log in

Relevant bibliographies by topics / Skipped cycles / Journal articles

To see the other types of publications on this topic, follow the link: Skipped cycles.

Journal articles on the topic 'Skipped cycles'

Author: Grafiati

Published: 7 July 2024

Last updated: 31 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Skipped cycles.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Burlon, S., H. Mroueh, and J. P. Cao. "‘Skipped cycles’ method for studying cyclic loading and soil–structure interface." Computers and Geotechnics 61 (September 2014): 209–20. http://dx.doi.org/10.1016/j.compgeo.2014.05.007.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Cucco, Marco, Marco Grenna, and Irene Pellegrino. "Egg Characteristics in Relation to Skipped Days of Laying in the Grey Partridge." Avian Biology Research 10, no. 4 (2017): 231–40. http://dx.doi.org/10.3184/175815617x15036738758853.

Full text

Abstract:

Birds sometimes skip a day along the sequence of egg laying, which may vary the mass or the composition of delayed eggs compared with those that were laid consecutively. Our literature review shows that this has been interpreted as a short-term adaptation that enables females to overcome energetic constraints during the laying period, but other hypotheses implying the influence of weather, pollution, or hormonal cycles have also been proposed. We collected freshly laid Grey Partridge Perdix perdix eggs to determine the effects of laying gaps on egg characteristics. Egg shape, as well as egg co

APA, Harvard, Vancouver, ISO, and other styles

3

Mäeorg, Uno, Andi Kipper, Indrek Kalvet, et al. "Synthesis of Unprotected CH2-Skipped Piperazine-Pyridine Alternating Cycles with Azide End-Group." HETEROCYCLES 90, no. 1 (2015): 625. http://dx.doi.org/10.3987/com-14-s(k)12.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Cui, X., and C. Q. Doe. "The role of the cell cycle and cytokinesis in regulating neuroblast sublineage gene expression in the Drosophila CNS." Development 121, no. 10 (1995): 3233–43. http://dx.doi.org/10.1242/dev.121.10.3233.

Full text

Abstract:

The precise temporal control of gene expression is critical for specifying neuronal identity in the Drosophila central nervous system (CNS). A particularly interesting class of genes are those expressed at stereotyped times during the cell lineage of identified neural precursors (neuroblasts): these are termed ‘sublineage’ genes. Although sublineage gene function is vital for CNS development, the temporal regulation of this class of genes has not been studied. Here we show that four genes (ming, even-skipped, unplugged and achaete) are expressed in specific neuroblast sublineages. We show that

APA, Harvard, Vancouver, ISO, and other styles

5

Rahman, Nayem. "Saving DBMS Resources While Running Batch Cycles in Data Warehouses." International Journal of Technology Diffusion 1, no. 2 (2010): 42–55. http://dx.doi.org/10.4018/jtd.2010040102.

Full text

Abstract:

In a large data warehouse, thousands of jobs run during each cycle in dozens of subject areas. Many of the data warehouse tables are quite large and they need to be refreshed at the right time, several times a day, to support strategic business decisions. To enable cycles to run more frequently and keep the data warehouse environment stable the database system’s resource utilization must be optimal. This paper discusses refreshing data warehouses using a metadata model to make sure jobs under batch cycles run on an as-needed basis. The metadata model limits execution of the stored procedures i

APA, Harvard, Vancouver, ISO, and other styles

6

Tonini, G., B. Vincenzi, E. Vasile, et al. "Phase II capecitabine and gemcitabine fixed dose rate (FDR) in patients with advanced pancreatic cancer." Journal of Clinical Oncology 27, no. 15_suppl (2009): e15530-e15530. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.e15530.

Full text

Abstract:

e15530 Background: The aims of this phase II trial are to determine the activity and the safety of the new combination modality with Gemcitabine fixed dose rate (FDR) infusion and Capecitabine in patients with advanced pancreatic cancer. Methods: Patients with unresectable pancreatic cancer who had pathologically confirmed adenocarcinoma, no prior chemotherapy, ECOG PS < 2 and measurable disease were enrolled. Gemcitabine (800 mg/mq IV infused in 80 minutes on days 1 and 8) and Capecitabine (650 mg/mq orally twice daily for 14 days) were administered and repeated every 21 days. Results: 47

APA, Harvard, Vancouver, ISO, and other styles

7

Stark, Lloyd R. "Skipped reproductive cycles and extensive sporophyte abortion in the desert moss Tortula inermis correspond to unusual rainfall patterns." Canadian Journal of Botany 80, no. 5 (2002): 533–42. http://dx.doi.org/10.1139/b02-053.

Full text

Abstract:

A phenological assessment of Tortula inermis (Brid.) Mont. populations in the Mojave Desert, Nevada, U.S.A., over a period of 4 years revealed that the sporophyte cohort initiated in early 1995 remained dormant until early 1998, by which time approximately 66% of the sporophytes had aborted. The viable sporophytes of this cohort were significantly shorter in length and had significantly less biomass than the previous cohort of sporophytes. In the intervening years 1996 and 1997, the sexual reproductive cycle was skipped altogether. The absence of sporophyte initiation in these two years was at

APA, Harvard, Vancouver, ISO, and other styles

8

Li, Zhaoxia, Jie Tang, Diane C. Bassham, and Stephen H. Howell. "Daily temperature cycles promote alternative splicing of RNAs encoding SR45a, a splicing regulator in maize." Plant Physiology 186, no. 2 (2021): 1318–35. http://dx.doi.org/10.1093/plphys/kiab110.

Full text

Abstract:

Abstract Elevated temperatures enhance alternative RNA splicing in maize (Zea mays) with the potential to expand the repertoire of plant responses to heat stress. Alternative RNA splicing generates multiple RNA isoforms for many maize genes, and here we observed changes in the pattern of RNA isoforms with temperature changes. Increases in maximum daily temperature elevated the frequency of the major modes of alternative splices (AS), in particular retained introns and skipped exons. The genes most frequently targeted by increased AS with temperature encode factors involved in RNA processing an

APA, Harvard, Vancouver, ISO, and other styles

9

Mobarak, Ahmed Mushfiq, and Maira Emy Reimão. "Seasonal Poverty and Seasonal Migration in Asia." Asian Development Review 37, no. 1 (2020): 1–42. http://dx.doi.org/10.1162/adev_a_00139.

Full text

Abstract:

Four in five poor people in the Asia and Pacific region live in rural areas. Crop cycles in agrarian areas create periods of seasonal deprivation, or preharvest “lean seasons,” when work is scarce and skipped meals become frequent. In this paper, we document this phenomenon of seasonal poverty and discuss existing formal mechanisms for coping with it. We then focus on seasonal migration from rural to urban areas as a potential coping strategy and review the evidence on the effects of encouraging seasonal migration through transport subsidies. Over the past 10 years, we have conducted a series

APA, Harvard, Vancouver, ISO, and other styles

10

Sikov, William M., Donald A. Berry, Charles M. Perou, et al. "Impact of the Addition of Carboplatin and/or Bevacizumab to Neoadjuvant Once-per-Week Paclitaxel Followed by Dose-Dense Doxorubicin and Cyclophosphamide on Pathologic Complete Response Rates in Stage II to III Triple-Negative Breast Cancer: CALGB 40603 (Alliance)." Journal of Clinical Oncology 33, no. 1 (2015): 13–21. http://dx.doi.org/10.1200/jco.2014.57.0572.

Full text

Abstract:

Purpose One third of patients with triple-negative breast cancer (TNBC) achieve pathologic complete response (pCR) with standard neoadjuvant chemotherapy (NACT). CALGB 40603 (Alliance), a 2 × 2 factorial, open-label, randomized phase II trial, evaluated the impact of adding carboplatin and/or bevacizumab. Patients and Methods Patients (N = 443) with stage II to III TNBC received paclitaxel 80 mg/m2 once per week (wP) for 12 weeks, followed by doxorubicin plus cyclophosphamide once every 2 weeks (ddAC) for four cycles, and were randomly assigned to concurrent carboplatin (area under curve 6) on

APA, Harvard, Vancouver, ISO, and other styles

11

Santini, D., B. Vincenzi, E. Vasile, et al. "Fixed dose rate (FDR) gemcitabine (G) and capecitabine (C) in patients with metastatic biliary tract cancer (BTC): Final results of phase II trial." Journal of Clinical Oncology 27, no. 15_suppl (2009): e15510-e15510. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.e15510.

Full text

Abstract:

e15510 Background: The combination of fixed dose rate (FDR) gemcitabine (C) and capecitabine (G) has been demonstrated to be well tolerated in patients with advanced cancers. To determine the activity and safety of this combination in metastatic metastatic biliary tract cancer patients, a phase II trial was conducted. Methods: Patients with unresectable BTC who had pathologically confirmed adenocarcinoma, no prior chemotherapy, ECOG PS < 2 and measurable disease were enrolled. Treatment consisted of FDR G at 800 mg/m(2) infused in 80 minutes on days 1 and 8 every 21 days with C administered

APA, Harvard, Vancouver, ISO, and other styles

12

Mirza, M. R., B. Lund, K. Bertelsen, et al. "Pegylated liposomal doxorubicin (PLD) and gemcitabine (GEM) in combination in the salvage treatment of epithelial ovarian cancer (OC)—a Danish Gynaecologic Cancer Group (DGC) study." Journal of Clinical Oncology 24, no. 18_suppl (2006): 5094. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.5094.

Full text

Abstract:

5094 Background: Ovarian cancer patients (pts) recurring with a short treatment-free interval (TFI) after prior chemotherapy (PCT) have a bad prognosis. DGC has conducted a phase II study of PLD-GEM in combination in OC pts recurring with a TFI of less than 12 months (mo). Methods: All pts must have received at least one platinum-paclitaxel containing regimen; no PCT with GEM or anthracyclines. Regimen: GEM 800mg/m2 day 1+8 and PLD 25mg/m2 day 1, q 21 days. GEM dose escalation to 1g/m2 day 1+8 from 2. cycle in the absence of grade 3–4 toxicity. Primary end point: OS, secondary: PFS, response a

APA, Harvard, Vancouver, ISO, and other styles

13

Mirzaghaderi, Ghader, and Elvira Hörandl. "The evolution of meiotic sex and its alternatives." Proceedings of the Royal Society B: Biological Sciences 283, no. 1838 (2016): 20161221. http://dx.doi.org/10.1098/rspb.2016.1221.

Full text

Abstract:

Meiosis is an ancestral, highly conserved process in eukaryotic life cycles, and for all eukaryotes the shared component of sexual reproduction. The benefits and functions of meiosis, however, are still under discussion, especially considering the costs of meiotic sex. To get a novel view on this old problem, we filter out the most conserved elements of meiosis itself by reviewing the various modifications and alterations of modes of reproduction. Our rationale is that the indispensable steps of meiosis for viability of offspring would be maintained by strong selection, while dispensable steps

APA, Harvard, Vancouver, ISO, and other styles

14

Balduzzi, Francesco, Luca Romani, Lorenzo Bosi, and Giovanni Ferrara. "Intermittent Injection for a Two-Stroke Direct Injection Engine." SAE International Journal of Advances and Current Practices in Mobility 2, no. 2 (2020): 1013–21. http://dx.doi.org/10.4271/2019-32-0524.

Full text

Abstract:

<div class="section abstract"><div class="htmlview paragraph">Cycle-to-cycle variation is one of the main factors for high fuel consumption and emissions of a two-stroke engine during the low-load and low-speed running. The increase of residual gas ratio due to the lower delivered amount of fresh scavenging air leads to a lower flame front speed and, therefore, to a slow combustion or even misfiring. The consequence is a very high level of unburnt hydrocarbons, since a large amount of fuel does not take part in the combustion process.</div><div class="htmlview paragraph"&g

APA, Harvard, Vancouver, ISO, and other styles

15

Dej, K. J., and A. C. Spradling. "The endocycle controls nurse cell polytene chromosome structure during Drosophila oogenesis." Development 126, no. 2 (1999): 293–303. http://dx.doi.org/10.1242/dev.126.2.293.

Full text

Abstract:

Polytene chromosomes exhibit intricate higher order chromatin structure that is easily visualized due to their precisely aligned component strands. However, it remains unclear if the same factors determine chromatin organization in polyploid and diploid cells. We have analyzed one such factor, the cell cycle, by studying changes in Drosophila nurse cell chromosomes throughout the 10 to 12 endocycles of oogenesis. We find that nurse cells undergo three distinct types of endocycle whose parameters are correlated with chromosome behavior. The first four endocycles support complete DNA replication

APA, Harvard, Vancouver, ISO, and other styles

16

Sukhinov, Alexander, Yulia Belova, Natalia Panasenko, and Valentina Sidoryakina. "Research of the Solutions Proximity of Linearized and Nonlinear Problems of the Biogeochemical Process Dynamics in Coastal Systems." Mathematics 11, no. 3 (2023): 575. http://dx.doi.org/10.3390/math11030575.

Full text

Abstract:

The article considers a non-stationary three-dimensional spatial mathematical model of biological kinetics and geochemical processes with nonlinear coefficients and source functions. Often, the step of analytical study in models of this kind is skipped. The purpose of this work is to fill this gap, which will allow for the application of numerical modeling methods to a model of biogeochemical cycles and a computational experiment that adequately reflects reality. For this model, an initial-boundary value problem is posed and its linearization is carried out; for all the desired functions, thei

APA, Harvard, Vancouver, ISO, and other styles

17

Le Gouill, Steven, Krimo Bouabdallah, Guillaume Cartron, et al. "T3 : A Multicenter Phase IB Dose Escalation Study to Evaluate the Safety, Feasibility and Efficacy of the Temsirolimus (Torisel™)-CHOP-Rituximab (T-R-CHOP), Temsirolimus (Torisel™)-FC-Rituximab (T-R-FC) and Temsirolimus (Torisel™)- DHA-Rituximab (T-R-DHA) for the Treatment of Patients with Relapsed/Refractory Mantle Cell Lymphoma (MCL), a Lysa Study." Blood 124, no. 21 (2014): 4426. http://dx.doi.org/10.1182/blood.v124.21.4426.4426.

Full text

Abstract:

Abstract The T3 trial is a multicenter Phase IB dose escalation study that evaluates the safety, feasibility and efficacy of three Temsirolimus-based chemotherapy regimens: Temsirolimus(Torisel™)-CHOP-Rituximab (T-R-CHOP), Temsirolimus(Torisel™)-FC-Rituximab (T-R-FC) and Temsirolimus(Torisel™)-Dexamethasone-aracytine-Rituximab (T-R-DHA) for the treatment of patients with relapsed/refractory Mantle Cell Lymphoma (MCL). The choice of the chemotherapy regimen was left to the decision of local investigator. The primary objective of the T3 was to assess the feasibility and incidence of dose limitin

APA, Harvard, Vancouver, ISO, and other styles

18

Kamaraju, Sailaja, Saranya Chumsri, Blaise Bayer, et al. "Differential efficacy of SV-BR-1-GM in inducing intracranial metastasis regression." Journal of Clinical Oncology 42, no. 16_suppl (2024): e13119-e13119. http://dx.doi.org/10.1200/jco.2024.42.16_suppl.e13119.

Full text

Abstract:

e13119 Background: Breast cancer metastasis to the central nervous system (CNS) and intracranial area often leads to severe morbidity and mortality. While systemic treatments manage systemic tumors, their impact on CNS/intracranial metastases is limited. Cell based therapies like SV-BR-1-GM may overcome this limitation. SV-BR-1-GM is a GM-CSF secreting, antigen-presenting immortalized breast cancer cell line. We report its efficacy on CNS tumor regression. Methods: Post-hoc analysis of a subset of all advanced MBC patients with CNS/intracranial metastases from previous phase 1, 2, and an ongoi

APA, Harvard, Vancouver, ISO, and other styles

19

Saxena, Shreya, Sridevi V. Sarma, and Munther Dahleh. "Performance Limitations in Sensorimotor Control: Trade-Offs Between Neural Computation and Accuracy in Tracking Fast Movements." Neural Computation 32, no. 5 (2020): 865–86. http://dx.doi.org/10.1162/neco_a_01272.

Full text

Abstract:

The ability to move fast and accurately track moving objects is fundamentally constrained by the biophysics of neurons and dynamics of the muscles involved. Yet the corresponding trade-offs between these factors and tracking motor commands have not been rigorously quantified. We use feedback control principles to quantify performance limitations of the sensorimotor control system (SCS) to track fast periodic movements. We show that (1) linear models of the SCS fail to predict known undesirable phenomena, including skipped cycles, overshoot and undershoot, produced when tracking signals in the

APA, Harvard, Vancouver, ISO, and other styles

20

Hess, D., S. Boehm, A. Delmonte, et al. "Clinical development of namitecan (ST1968), a novel camptothecin derivative with high antitumor activity: Phase I clinical data." Journal of Clinical Oncology 27, no. 15_suppl (2009): 2570. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.2570.

Full text

Abstract:

2570 Background: Namitecan is a new water-soluble camptothecin analogue which showed high antitumor activity in preclinical models. Aim of this trial was to determine safety, PK profile and activity in adult patients with advanced solid tumors. Methods: The dose escalation started at 2.5 mg i.v. on days 1 and 8 of a 21 day cycle (D1, D8 Q21D) and increased according to 3+3 cohort design depending on the observed toxicity. Dose limiting toxicity (DLT) definitions were: ANC <0.5x109/L for >5 days; PLT ≥ Grade 3 (CTC V3); grade ≥2 liver/renal toxicity not recovered by D22; any non-hematolog

APA, Harvard, Vancouver, ISO, and other styles

21

Kamaraju, Sailaja, Blaise Bayer, Mingjin Chang, William Williams, Charles Wiseman, and Giuseppe Del Priore. "Abstract CT204: Efficacy of Bria-IMT regimen in inducing CNS metastasis regression." Cancer Research 84, no. 7_Supplement (2024): CT204. http://dx.doi.org/10.1158/1538-7445.am2024-ct204.

Full text

Abstract:

Abstract Objectives: Breast cancer metastasis to the central nervous system (CNS) often leads to severe morbidity and mortality, and while systemic treatments manage primary tumors, their impact on CNS metastases is limited. This retrospective analysis evaluates the efficacy of Bria-IMT as a monotherapy or in combination with an immune checkpoint inhibitor (ICI) on CNS tumor regression. Methods: Post-hoc analysis of a subset of advanced MBC patients with CNS metastases from previous phase 1 and 2, and ongoing randomized phase 2 trials involving SV-BR-1-GM. SV-BR-1-GM is a GM-CSF secreting, ant

APA, Harvard, Vancouver, ISO, and other styles

22

Lindberg, Kurt R., William C. Daniels, Isla S. Castañeda, and Julie Brigham-Grette. "Biomarker proxy records of Arctic climate change during the Mid-Pleistocene transition from Lake El'gygytgyn (Far East Russia)." Climate of the Past 18, no. 3 (2022): 559–77. http://dx.doi.org/10.5194/cp-18-559-2022.

Full text

Abstract:

Abstract. The Mid-Pleistocene Transition (MPT) is a widely recognized global climate shift occurring between approximately 1250 and 700 ka. At this time, Earth's climate underwent a major transition from dominant 40 kyr glacial–interglacial cycles to quasi-100 kyr cycles. The cause of the MPT remains a puzzling aspect of Pleistocene climate. Presently, there are few, if any, continuous MPT records from the Arctic, yet understanding the role and response of the high latitudes to the MPT is required to better evaluate the causes of this climatic shift. Here, we present new continental biomarker

APA, Harvard, Vancouver, ISO, and other styles

23

Calatayud, N. E., D. M. Shier, R. R. Swaisgood, and B. S. Durrant. "119 HORMONE-ASSISTED REPRODUCTION IN A CAPTIVE MOUNTAIN YELLOW-LEGGED FROG POPULATION." Reproduction, Fertility and Development 28, no. 2 (2016): 189. http://dx.doi.org/10.1071/rdv28n2ab119.

Full text

Abstract:

Severe declines of the mountain yellow-legged frog (MYLF, Rana muscosa) led to establishment of a captive population at the San Diego Zoo Institute for Conservation Research. With less than 200 adults estimated to remain in the wild, the Institute’s MYLF colony currently holds approximately 30% of the entire gene pool. Simulating natural seasonality by artificial brumation and manipulation of atmospheric temperature and light cycles is an integral part of this species’ management in captivity. However, over 5 years, the number of females that have oviposited has decreased from 80% in 2011 to 2

APA, Harvard, Vancouver, ISO, and other styles

24

Long, Rong, Xiaohui Fan, Kai Wei, Junxuan Bai, and Shanpeng Xiao. "Internet-of-Things object model." Digital Twin 2 (April 12, 2022): 5. http://dx.doi.org/10.12688/digitaltwin.17562.1.

Full text

Abstract:

Background: With the advancement of communication technology and advanced sensors, there are massive demands for Internet-of-Things (IoT) applications in buildings, communities, factories, parks, etc. Accessing IoT devices provides convenience for scene management and monitoring, ameliorating production and life intelligently. However, due to the lack of a unified model for IoT devices, data is often skipped over IoT platforms and transmitted to applications directly. This leads to the fact that each manufacturer needs to produce its devices and develop its customized software, which hugely in

APA, Harvard, Vancouver, ISO, and other styles

25

Lacombe, D. A., F. Caponigro, A. Anthoney, et al. "A phase I study of bortezomib in combination with 5FU/LV plus oxaliplatin in patients (pts) with advanced colorectal cancer (CRC): EORTC 16029." Journal of Clinical Oncology 25, no. 18_suppl (2007): 4090. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.4090.

Full text

Abstract:

4090 Background: Bortezomib is a potent and reversible inhibitor of the ubiquitin-mediated proteasome pathway, whose inhibition results in the stabilization of p53, p21Cip1, p27Kip1, Bax, in cell-cycle dysregulation and, finally, apoptosis. A phase I study of the combination of 5FU/LV and bortezomib has shown a significant stable disease rate in advanced CRC (Iqbal, ASCO 2004). Methods: In this phase I study bortezomib was given as an IV push over 3 to 5 seconds on days 1, 8 and 15 in combination with standard FOLFOX-4 every 28 days in chemo-naïve pts with advanced CRC. Bortezomib starting dos

APA, Harvard, Vancouver, ISO, and other styles

26

Lu, Jiaying, Yuanjie Chen, Zihan Wang, et al. "Larval Dispersal Modeling Reveals Low Connectivity among National Marine Protected Areas in the Yellow and East China Seas." Biology 12, no. 3 (2023): 396. http://dx.doi.org/10.3390/biology12030396.

Full text

Abstract:

Marine protected areas (MPAs) are vital for protecting biodiversity, maintaining ecosystem integrity, and tackling future climate change. The effectiveness of MPA networks relies on connectivity, yet connectivity assessments are often skipped in the planning process. Here we employed a multi-species biophysical model to examine the connectivity patterns formed among the 21 national MPAs in the Yellow and East China Seas. We simulated the potential larval dispersal of 14 oviparous species of five classes. Larvae of non-migratory species with pelagic larval duration (PLD) were assumed to be pass

APA, Harvard, Vancouver, ISO, and other styles

27

Gorelik, Gennady Bencianovich, Anatoly Nikolaevich Sobolenko, and Sergey Vital'evich Pastukhov. "Prospects for the diesel fuel equipment development in the near future." Vestnik of Astrakhan State Technical University. Series: Marine engineering and technologies 2024, no. 1 (2024): 58–63. http://dx.doi.org/10.24143/2073-1574-2024-1-58-63.

Full text

Abstract:

The analysis of the positive qualities of Common Rail (CR) fuel equipment widely used in diesels today is given. The possibility of optimal diesel control, high injection pressure, elimination of repeated fuel injections, improvement of fuel efficiency, reduction of the difference in the amplitude of torque fluctuations in the cylinders, very precise regulation of the beginning of fuel supply, a high degree of diagnosability of fuel equipment, the possibility of precise regulation of the uniformity of fuel supply through the cylinders, the ability to ensure optimal regulation of the turbocharg

APA, Harvard, Vancouver, ISO, and other styles

28

Weigmann, K., and C. F. Lehner. "Cell fate specification by even-skipped expression in the Drosophila nervous system is coupled to cell cycle progression." Development 121, no. 11 (1995): 3713–21. http://dx.doi.org/10.1242/dev.121.11.3713.

Full text

Abstract:

The correct specification of defined neurons in the Drosophila central nervous system is dependent on even-skipped. During CNS development, even-skipped expression starts in the ganglion mother cell resulting from the first asymmetric division of neuroblast NB 1–1. This first division of NB 1–1 (and of the other early neuroblasts as well) is temporally controlled by the transcriptional regulation of string expression, which we have manipulated experimentally, even-skipped expression still occurs if the first neuroblast division is delayed, but not if the division is prohibited. Moreover, even-

APA, Harvard, Vancouver, ISO, and other styles

29

Cui, Jiujie, Haiyan Yang, Jiong Hu, et al. "Anti-PD-1 antibody combined with albumin-bound paclitaxel and gemcitabine (AG) as first-line therapy and Anti-PD-1 monotherapy as maintenance in metastatic pancreatic ductal adenocarcinoma (PDAC)." Journal of Clinical Oncology 39, no. 15_suppl (2021): e16218-e16218. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e16218.

Full text

Abstract:

e16218 Background: Two studies in ASCO 2018 showed the preliminary efficacy of PD-1 inhibitor and AG as first-line therapy for advanced pancreatic cancer, the disease control rate (DCR) was up to 100%. However, in a phase 1 study of nivolumab plus nab-paclitaxel and gemcitabine in advanced PDAC, the objective response rate (ORR) was only 18%, and the progression-free survival (PFS)/overall survival (OS) were 5.5/9.9 months, which was quite different from what had been reported before in ASCO. All the patients received continuous chemotherapy, and the tolerance was poor. Recently, maintenance t

APA, Harvard, Vancouver, ISO, and other styles

30

Zilioli, Vittorio Ruggero, Periana Minga, Lara Crucitti, et al. "NEPA (netupitant + palonosetron) Administration Is Safe and Effective in cHL Patients Receiving ABVD Regimen: A Single-Center Real Life Experience." Blood 132, Supplement 1 (2018): 5374. http://dx.doi.org/10.1182/blood-2018-99-116543.

Full text

Abstract:

Abstract BACKGROUND In the setting of cHL, ABVD (adriamycin, bleomycin, vinblastine, dacarbazine) is the most widely used first line chemotherapeutic treatment and it is well known that this regimen is associated with a high emetic risk (HEC). Palonosetron (PALO) currently represents one of the most effective and implemented drug for CINV prevention, but after many ABVD cycles patients (pts) frequently need to add other antiemetic drugs to obtain a good control of their symptoms. Netupitant (NETU) is the NK1-RA (neurokinin receptor antagonist) component of NEPA, the first antiemetic drug avail

APA, Harvard, Vancouver, ISO, and other styles

31

Sailo, Lalrintlingi, Apurba Sarkar, and Suresh Babu. "A STUDY ON STATUS OF URINARY HYDROXYPROLINE IN POST MENOPAUSAL WOMEN." International Journal of Advanced Research 9, no. 03 (2021): 136–46. http://dx.doi.org/10.21474/ijar01/12566.

Full text

Abstract:

Introduction: WHO and the Stages of Reproductive Aging Workshop have defined menopausal transition as the time of an increase in follicle-stimulating hormone and either increased variability in menstrual cycle length, two skipped menstrual cycles with 60 days or more of amenorrhea, or both. It concludes with the final menstrual period. Post-menopause begins at that time, although it is not recognized until after 12 months of amenorrhea. During menopause, women face various physiological, psychological, and biochemical changes. Laboratory medicine has given a new background to overcome the clin

APA, Harvard, Vancouver, ISO, and other styles

32

Yoshino, S., M. Oka, S. Hazama, R. Shimizu, and T. Yamamoto. "A combination phase I study of biweekly docetaxel and 5’-DFUR in patients with unresectable or recurrent gastric cancer." Journal of Clinical Oncology 24, no. 18_suppl (2006): 14115. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.14115.

Full text

Abstract:

14115 Background: Docetaxel (DOC) and 5’-DFUR (an intermetamolite of capecitabine) have single-agent activity in gastric cancer and have distinct mechanisms of action and no overlap of key toxicities. Synergistic interaction between DOC and 5’-DFUR is mediated by taxane-induced up-regulation of thymidine phosphorylase. The objectives of this study were to determine the maximum tolerated dose (MTD), the dose limiting toxicity (DLT) and the recommended dose (RD) of the combination therapy of biweekly DOC and 5’-DFUR. The DLT was set in low grade to treat the patients in the outpatient clinic. Me

APA, Harvard, Vancouver, ISO, and other styles

33

Spira, A. I., N. O. Iannotti, M. A. Savin, et al. "Phase II study of eribulin mesylate (E7389), a mechanistically novel inhibitor of microtubule dynamics, in patients with advanced non-small cell lung cancer (NSCLC)." Journal of Clinical Oncology 25, no. 18_suppl (2007): 7546. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.7546.

Full text

Abstract:

7546 Background: Eribulin is a structurally-simplified, fully synthetic analog of the marine sponge natural product halichondrin B. Eribulin inhibits microtubule dynamics via a mechanistically novel mode of action. Methods: An open-label, single-arm, Phase II study of eribulin was conducted in patients with advanced NSCLC (ECOG of 0 or 1) who were treated with platinum-based doublet chemotherapy and stratified by prior taxane exposure. A total of 103 patients (83 with prior taxanes and 20 taxane naïve) were treated with eribulin (1.4 mg/m2), administered as a bolus infusion over 2 –5 minutes o

APA, Harvard, Vancouver, ISO, and other styles

34

Liu, Ting, Pu Kuang, Tian Dong, et al. "Imatinib 400mg Daily Combined with Vindesine and Dexamethasone As Induction and Maintenance Therapy for Philadelphia Chromosome-Positive Acute Lymphocytic Leukemia." Blood 118, no. 21 (2011): 4243. http://dx.doi.org/10.1182/blood.v118.21.4243.4243.

Full text

Abstract:

Abstract Abstract 4243 [Background] Imatinib combined with intensive chemotherapy protocol markedly has markedly improved the prognosis of patients with Philadelphia chromosome-positive acute lymphocytic leukemia (Ph+ALL), and has become the standard therapy for this disease. Based on experience from patients with chronic myelogenous leukemia in blast crisis or accelerated phase, this highly specific tyrosine kinase inhibitor was given 600mg or 800mg daily in most clinical trials. However, some pilot study and case report implied that either lower dose of imatinib or less intensive chemotherap

APA, Harvard, Vancouver, ISO, and other styles

35

Yao, Gang, Nuno V. da Silva, Michael Warner, Di Wu, and Chenhao Yang. "Tackling cycle skipping in full-waveform inversion with intermediate data." GEOPHYSICS 84, no. 3 (2019): R411—R427. http://dx.doi.org/10.1190/geo2018-0096.1.

Full text

Abstract:

Full-waveform inversion (FWI) is a promising technique for recovering the earth models for exploration geophysics and global seismology. FWI is generally formulated as the minimization of an objective function, defined as the L2-norm of the data residuals. The nonconvex nature of this objective function is one of the main obstacles for the successful application of FWI. A key manifestation of this nonconvexity is cycle skipping, which happens if the predicted data are more than half a cycle away from the recorded data. We have developed the concept of intermediate data for tackling cycle skipp

APA, Harvard, Vancouver, ISO, and other styles

36

Desanti de Oliveira, Beatriz, David DeStephano, Melissa Parsons Beauchemin, et al. "Implementation of EHR medication-adherence screening tool in breast cancer clinic." Journal of Clinical Oncology 40, no. 28_suppl (2022): 438. http://dx.doi.org/10.1200/jco.2022.40.28_suppl.438.

Full text

Abstract:

438 Background: Nonadherence to prescribed medications occurs frequently in patient with breast cancer (BC) and can affect BC outcomes as well as outcomes for comorbid conditions. We implemented a process to screen for medication adherence in the electronic health record (EHR) in an urban outpatient BC clinic. Methods: Plan-Do-Study-Act (PDSA) methodology was used to implement a screening process for medication adherence for all patients seen in the outpatient breast oncology clinic. At check-in (via the patient portal or clinic based kiosks), patients were asked to complete an EHR adherence s

APA, Harvard, Vancouver, ISO, and other styles

37

Trneny, M., U. Jaeger, O. Belohlavek, et al. "Prediction of outcome using positron emission tomography (PET) compared to standard response criteria and potential role in treatment decisions in diffuse large B-cell lymphoma (DLBCL) patients." Journal of Clinical Oncology 24, no. 18_suppl (2006): 7565. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.7565.

Full text

Abstract:

7565 Background: PET has been demonstrated to give valid information about viable tumor residua. There are however only limited data regarding the combination of classical response criteria with PET and there is a lack of information on the impact of additional therapy (add-Th) on the outcome of PET neg. or PET pos. pts. Methods: One hundred thirty-nine pts (median age 50y) with newly diagnosed DLBCL who were examined by PET during (after 2–4 cycles CHT - ‘early PET’) or/and at the end of therapy (‘end PET’) were analyzed retrospectively. IPI risk distribution were as follows: L 28%, LI 24%, I

APA, Harvard, Vancouver, ISO, and other styles

38

Zhang, Jing, Qian Cong, Xiao-Ling Fan, Rongjiang Wang, Min Wang, and Nick V. Grishin. "Mitogenomes of Giant-Skipper Butterflies reveal an ancient split between deep and shallow root feeders." F1000Research 6 (March 6, 2017): 222. http://dx.doi.org/10.12688/f1000research.10970.1.

Full text

Abstract:

Background: Giant-Skipper butterflies from the genus Megathymus are North American endemics. These large and thick-bodied Skippers resemble moths and are unique in their life cycles. Grub-like at the later stages of development, caterpillars of these species feed and live inside yucca roots. Adults do not feed and are mostly local, not straying far from the patches of yucca plants. Methods: Pieces of muscle were dissected from the thorax of specimens and genomic DNA was extracted (also from the abdomen of a specimen collected nearly 60 years ago). Paired-end libraries were prepared and sequenc

APA, Harvard, Vancouver, ISO, and other styles

39

Duke, J. H. "Do periodic consolidations of Pacific countercurrents trigger global cooling by equatorially symmetric La Niña?" Climate of the Past Discussions 6, no. 3 (2010): 905–61. http://dx.doi.org/10.5194/cpd-6-905-2010.

Full text

Abstract:

Abstract. A sporadic phenomenon of internal tide resonance (ITR) in the western equatorial Pacific thermocline is shown to precede 11 of 12 major upturns in the Niño 3.4 index between 1992 and 2008. Observed ITR has up to 9 °C semidiurnal temperature excursions indicating thermocline heave, but is invisible in time resolution longer than one day. It is independent of westerly wind bursts (WWB). A hypothesis is advanced that (1) ITR dissipates vorticity, leading to Pacific countercurrent consolidation (PCC) by reducing the vortex stretching term in Sverdrup balance. The consequence of lost vort

APA, Harvard, Vancouver, ISO, and other styles

40

Zailani, Rosilatul, Gani Priambodo, and Yohannes Sardjono. "NEUTRON AND GAMMA SPECTRUM ANALYSIS OF KARTINI RESEARCH REACTOR FOR BORON NEUTRON CAPTURE THERAPY (BNCT)." JURNAL TEKNOLOGI REAKTOR NUKLIR TRI DASA MEGA 20, no. 2 (2018): 59. http://dx.doi.org/10.17146/tdm.2018.20.2.4067.

Full text

Abstract:

MCNPX was used to design a three-dimensional model of Kartini Research Reactor (KRR) as a neutron source and performed criticality calculation. The criticality calculation of the reactor aims to obtain the neutron and gamma spectrum by simulating the fission reaction inside the reactor core. Total source histories were 105 per cycle, when the number of cycle for criticality calcutation was 1000 cycles with 60 skipped cycles. The reactor criticality according to the simulation result is 1.00179±0.00007. The total neutron flux on ring A, B, C, D, E and F inside the reactor core are respectively

APA, Harvard, Vancouver, ISO, and other styles

41

Pacitti, A., F. G. Casino, L. Pedrini, A. Santoro, and M. Atti. "Prescription and Surveillance of the Acetate-Free Biofiltration Sessions: The Bicarbonate Cycle." International Journal of Artificial Organs 18, no. 11 (1995): 722–25. http://dx.doi.org/10.1177/039139889501801107.

Full text

Abstract:

A computerized system, structured by 4 different models concerning urea depuration, and bicarbonate and sodium handling in acetate-free hemodiafiltration has been conceived for integrated use covering each step of the therapeutic cycle, from a) the prescription of the session to b) its delivery, up to c) the dose - response analysis: the system, now fully developed for the bicarbonate cycle, covers both working areas; the medical one, with a program implemented on a Personal Computer, called Skipper which deals with steps a) and c), and the nursing area, with a program built into the dialytic

APA, Harvard, Vancouver, ISO, and other styles

42

Wesselink, Amelia K., Lauren A. Wise, Elizabeth E. Hatch, et al. "Seasonal patterns in fecundability in North America and Denmark: a preconception cohort study." Human Reproduction 35, no. 3 (2020): 565–72. http://dx.doi.org/10.1093/humrep/dez265.

Full text

Abstract:

Abstract STUDY QUESTION To what extent does fecundability vary across seasons? SUMMARY ANSWER After accounting for seasonal patterns in pregnancy planning, we observed higher fecundability in the fall and lower fecundability in the spring, particularly at lower latitudes. WHAT IS KNOWN ALREADY In human populations, there are strong seasonal patterns of births that vary across geographic regions and time periods. However, previous studies of seasonality and fecundity are limited because they examine season of birth rather than season of conception and therefore neglect to account for seasonal v

APA, Harvard, Vancouver, ISO, and other styles

43

Gulle, S., Y. Erez, A. Karakas, et al. "AB0708 HIGH DRUG RETENTION RATES DESPITE B/TSDMARD INTERRUPTIONS IN COVID-19 PANDEMIC CHAOS." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 1386.1–1386. http://dx.doi.org/10.1136/annrheumdis-2021-eular.4068.

Full text

Abstract:

Background:A significant increased risk of COVID-19 related adverse outcomes of the biological or target-directed synthetic DMARDs (b/tsDMARDs) has not yet been reported. For this reason, it is recommended to continue b/tsDMARD treatments with maximum compliance with pandemic measures.Objectives:The aim of this study was to evaluate the effects of patients using b/tsDMARDs on drug survival and rheumatic disease control during pandemic.Methods:In this study, patients diagnosed with rheumatic disease using b/tsDMARDs and who were followed up during the 12-month period (January 2020-2021) includi

APA, Harvard, Vancouver, ISO, and other styles

44

Pawar, V. G., and K. Pancharatna. "Annual oviduct cycle in the Indian skipper frog,Rana cyanophlyctis(Schneider 1799): a morphological study." Tropical Zoology 12, no. 1 (1999): 79–88. http://dx.doi.org/10.1080/03946975.1999.10539379.

Full text

APA, Harvard, Vancouver, ISO, and other styles

45

Sandalcı, Tarkan, Derviş Erol, Battal Doğan, and Erdal Tunçer. "Energy and exergy analyses of skipped cycle mode in a single-cylinder engine fuelled with diesel and natural gas." International Journal of Exergy 39, no. 2 (2022): 173. http://dx.doi.org/10.1504/ijex.2022.10049452.

Full text

APA, Harvard, Vancouver, ISO, and other styles

46

Tunçer, Erdal, Battal Doğan, Tarkan Sandalcı, and Derviş Erol. "Energy and exergy analyses of skipped cycle mode in a single-cylinder engine fuelled with diesel and natural gas." International Journal of Exergy 39, no. 2 (2022): 173. http://dx.doi.org/10.1504/ijex.2022.125523.

Full text

APA, Harvard, Vancouver, ISO, and other styles

47

Supekar, S. C., and N. P. Gramapurohit. "Does temporal variation in predation risk affect antipredator responses of larval Indian Skipper Frogs (Euphlyctis cyanophlyctis)?" Canadian Journal of Zoology 98, no. 3 (2020): 202–9. http://dx.doi.org/10.1139/cjz-2019-0118.

Full text

Abstract:

Predation risk varies on a moment-to-moment basis, through day and night, lunar and seasonal cycles, and over evolutionary time. Hence, it is adaptive for prey animals to exhibit environment-specific behaviour, morphology, and (or) life-history traits. Herein, the effects of temporally varying predation risk on growth, behaviour, morphology, and life-history traits of larval Indian Skipper Frogs (Euphlyctis cyanophlyctis (Schneider, 1799)) were studied by exposing them to no risk, continuous, predictable, and unpredictable risks at different time points. Our results show that larval E. cyanoph

APA, Harvard, Vancouver, ISO, and other styles

48

DUERR, NATHAN, THALIA CORAHUA-ESPINOZA, QUINLYN BAINE, et al. "Immature stages, new host plant records and shelter structures of Troyus phyllides (Röber, 1925) and Thoon ponka Evans, 1955 in the Peruvian Amazon (Lepidoptera: Hesperiidae: Hesperiinae: Hesperiini)." Zootaxa 5200, no. 4 (2022): 372–90. http://dx.doi.org/10.11646/zootaxa.5200.4.6.

Full text

Abstract:

We describe here for the first time the complete immature life cycles and shelter structures of two Neotropical skipper butterflies in the subtribe Moncina, Troyus phyllides (Röber, 1925) and Thoon ponka Evans 1955, along with new natural host plant records for these species at Finca Las Piedras, Madre de Dios, Peru. Four eggs and a preantepenultimate larva of T. phyllides, as well as three eggs of Thoon ponka were collected in nature and each passed through five larval instars to adulthood. Troyus phyllides fed on a herbaceous species, Lasiacis ligulata Hitchcock & Chase (Poaceae: Panicoi

APA, Harvard, Vancouver, ISO, and other styles

49

Kawai, Shinji, and Atsuo Amano. "Negative regulation of Odd-skipped related 2 by TGF-beta achieves the induction of cellular migration and the arrest of cell cycle." Biochemical and Biophysical Research Communications 421, no. 4 (2012): 696–700. http://dx.doi.org/10.1016/j.bbrc.2012.04.064.

Full text

APA, Harvard, Vancouver, ISO, and other styles

50

Dreyling, Martin, Marco Ladetto, Jeanette K. Doorduijn, et al. "Triangle: Autologous Transplantation after a Rituximab/Ibrutinib/ara-c Containing Induction in Generalized Mantle Cell Lymphoma - a Randomized European MCL Network Trial." Blood 134, Supplement_1 (2019): 2816. http://dx.doi.org/10.1182/blood-2019-127863.

Full text

Abstract:

Background: Mantle cell lymphoma (MCL) is a distinct subtype of lymphoma with a wide variation of clinical course. Based on randomized trials of our network, current standard of care is a cytarabine-containing immunochemotherapy induction (Hermine, Lancet 2016) followed by autologous stem cell transplantation (SCT; Zöllner, ICML 2019) and rituximab maintenance for 3 years (Le Gouill, NEJM 2018). In relapsed MCL the BTK inhibitor ibrutinib achieves high response rates and ongoing remissions (Wang, NEJM 2013; Dreyling, Lancet 2016). This approach achieved especially longer remission durations in

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!