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1

Antanavičiūtė, Ieva, Vida Mildažienė, Edgaras Stankevičius, Thomas Herdegen, and Vytenis Arvydas Skeberdis. "Hyperthermia Differently Affects Connexin43 Expression and Gap Junction Permeability in Skeletal Myoblasts and HeLa Cells." Mediators of Inflammation 2014 (2014): 1–16. http://dx.doi.org/10.1155/2014/748290.

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Stress kinases can be activated by hyperthermia and modify the expression level and properties of membranous and intercellular channels. We examined the role of c-Jun NH2-terminal kinase (JNK) in hyperthermia-induced changes of connexin43 (Cx43) expression and permeability of Cx43 gap junctions (GJs) in the rabbit skeletal myoblasts (SkMs) and Cx43-EGFP transfected HeLa cells. Hyperthermia (42°C for 6 h) enhanced the activity of JNK and its target, the transcription factor c-Jun, in both SkMs and HeLa cells. In SkMs, hyperthermia caused a 3.2-fold increase in the total Cx43 protein level and e
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Koblents, Eugenia, Inés P. Mariño, and Joaquín Míguez. "Bayesian Computation Methods for Inference in Stochastic Kinetic Models." Complexity 2019 (January 20, 2019): 1–15. http://dx.doi.org/10.1155/2019/7160934.

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In this paper we investigate Monte Carlo methods for the approximation of the posterior probability distributions in stochastic kinetic models (SKMs). SKMs are multivariate Markov jump processes that model the interactions among species in biological systems according to a set of usually unknown parameters. The tracking of the species populations together with the estimation of the interaction parameters is a Bayesian inference problem for which Markov chain Monte Carlo (MCMC) methods have been a typical computational tool. Specifically, the particle MCMC (pMCMC) method has been shown to be ef
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Zhang, Yong, Xin Wang, Zongli Jiang, Junfeng Wei, Hiroyuki Enomoto, and Tetsuo Ohata. "Glacier Surface Mass Balance in the Suntar-Khayata Mountains, Northeastern Siberia." Water 11, no. 9 (2019): 1949. http://dx.doi.org/10.3390/w11091949.

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Arctic glaciers comprise a small fraction of the world’s land ice area, but their ongoing mass loss currently represents a large cryospheric contribution to the sea level rise. In the Suntar-Khayata Mountains (SKMs) of northeastern Siberia, in situ measurements of glacier surface mass balance (SMB) are relatively sparse, limiting our understanding of the spatiotemporal patterns of regional mass loss. Here, we present SMB time series for all glaciers in the SKMs, estimated through a glacier SMB model. Our results yielded an average SMB of −0.22 m water equivalents (w.e.) year−1 for the whole re
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Rani, Medi, Redamalla Rekha, and Kota Sunitha. "ID Based Multicast Secret-Key Management Scheme (SKMS) in MANETs." International Journal of Intelligent Engineering and Systems 11, no. 6 (2018): 199–208. http://dx.doi.org/10.22266/ijies2018.1231.20.

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Zhang, Qing-Wen, Heap-Yih Chong, Pin-Chao Liao, and Yao-Lin Wan. "Logistic regression modeling of implementation of corporate safety policy in international infrastructures." Engineering, Construction and Architectural Management 27, no. 10 (2020): 3031–50. http://dx.doi.org/10.1108/ecam-03-2019-0155.

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PurposeThis study aims to determine the influences of explanatory factors on the efficacy of the implementation of corporate safety policy (CSP) in international projects from the perspective of international contractors.Design/methodology/approachFour explanatory factors were identified for the implementation of CSP in international projects based on literature review. A questionnaire survey was then conducted among Chinese organizations that have been involved in international projects. In total, 121 valid responses were received from the questionnaire survey and were modeled using logistic
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Pateloup, Sylvain, Helene Chanal, and Emmanuel Duc. "Geometric and Kinematic Modelling of a New Parallel Kinematic Machine Tool: The Tripteor X7 Designed by PCI." Advanced Materials Research 112 (May 2010): 159–69. http://dx.doi.org/10.4028/www.scientific.net/amr.112.159.

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Today, Parallel Kinematic Machine tools (PKMs) appear in automotive and aeronautic industry. These machines propose high kinematic performances allowing a higher productivity than Serial Kinematic Machine tools (SKMs). However, this kinematic behaviour is anisotropic and a particular study is then necessary to locate the part in a workspace where the kinematic performances are well exploited. The study presented in this article deals with the determination of geometric and kinematic models of a new PKM : the Tripteor X7 designed by PCI. The inverse kinematic model expresses the joint coordinat
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Egorov, Evgeniy N., Nikolay I. Kol'tsov, Nikolay F. Ushmarin, and Sergey I. Sandalov. "RESEARCH OF OPERATIONAL AND DYNAMIC PROPERTIES OF RUBBER FOR PRODUCTS WORKING IN SEA WATER." IZVESTIYA VYSSHIKH UCHEBNYKH ZAVEDENII KHIMIYA KHIMICHESKAYA TEKHNOLOGIYA 63, no. 11 (2020): 96–102. http://dx.doi.org/10.6060/ivkkt.20206311.6307.

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The article studies the effect of trans-polynorbornene, general and special-purpose rubbers and fillers on the vulcanization characteristics of a rubber mixture, physical, mechanical, operational and dynamic properties of vulcanizates based on butadiene methylstyrene caoutchouc. The investigated model rubber mixture included SKMS-30ARK rubber, sulfur, 2,2'-dibenzthiazole disulfide, guanide F, zinc white, stearic acid, phenyl-2-naphthalamine, N-isopropyl-N'-phenyl-para-phenylenediamine, carbon blacks of grades P 514 and N 220, shungite powder and other ingredients. The rubber mixture was produc
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Lakshman, Tanay. "RELIABILITY EVALUATION OF COMPOSITE SYSTEM WITH AGING FAILURE." International Journal of Advanced Research 9, no. 5 (2021): 342–49. http://dx.doi.org/10.21474/ijar01/12842.

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Reliability is concerned with the system capability of survival. In the past forty years, customer expectations have been increasing in response to evolving new technologies. As part of these evolutions, they are demanding from their suppliers: products with higher quality, low initial cost, improved customer support and products that are easy and inexpensive to maintain. For a supplier to survive, succeed and be profitable in todays market, It must do the following: a) Constant improvement in the quality of the products. b) Minimization of the cost. c) Be flexible and responsive to the custom
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Guo, Xiufang, Agnes Badu-Mensah, Michael C. Thomas, Christopher W. McAleer, and James J. Hickman. "Characterization of Functional Human Skeletal Myotubes and Neuromuscular Junction Derived—From the Same Induced Pluripotent Stem Cell Source." Bioengineering 7, no. 4 (2020): 133. http://dx.doi.org/10.3390/bioengineering7040133.

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In vitro generation of functional neuromuscular junctions (NMJs) utilizing the same induced pluripotent stem cell (iPSC) source for muscle and motoneurons would be of great value for disease modeling and tissue engineering. Although, differentiation and characterization of iPSC-derived motoneurons are well established, and iPSC-derived skeletal muscle (iPSC-SKM) has been reported, there is a general lack of systemic and functional characterization of the iPSC-SKM. This study performed a systematic characterization of iPSC-SKM differentiated using a serum-free, small molecule-directed protocol.
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Goldstein, Richard A. "Skeletal Muscle Injury Biomarkers: Assay Qualification Efforts and Translation to the Clinic." Toxicologic Pathology 45, no. 7 (2017): 943–51. http://dx.doi.org/10.1177/0192623317738927.

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Skeletal muscle (SKM) injury or myopathy results in structural or functional defects in SKMs that can be caused by variety of factors such as (1) genetic, (2) drug-induced, (3) disease progression (cachexia), or (4) aging (sarcopenia). Creatine kinase (CK) and aspartate transaminase (AST) activity assays have been routinely used as SKM injury biomarkers, but they lack sensitivity and tissue specificity. In collaboration with the Predictive Safety Testing Consortium, we evaluated the diagnostic performance of a muscle injury biomarker panel (MIP) compared to CK and AST and their correlation wit
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Egorov, Evgeny N., Nikolay F. Ushmarin, Konstantin V. Efimov, Sergey I. Sandalov, Ivan S. Spiridonov, and Nikolay I. Koltsov. "The influence of functional ingredients on the technological properties of water-swelling rubber sealing elements." Butlerov Communications 58, no. 6 (2019): 146–51. http://dx.doi.org/10.37952/roi-jbc-01/19-58-6-146.

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The article investigated the influence of the nature and content of coutchoucs, sevilens, vulcanizing groups, fillers, plasticizers, ingredients of directional action on the technological properties (plasticity, ring modulus, density, start time of vulcanization, stickiness) of two rubber mixtures. These indicators characterize the processability of rubber compounds in the manufacture of products from them. The study was conducted in order to select the basis of rubber compounds for the manufacture of the outer and inner layers of water-swellable sealing elements (WSSE). It has been establishe
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Egorov, Evgeny N., Nikolay F. Ushmarin, Sergey I. Sandalov, Ivan S. Spiridonov, and Nikolay I. Koltsov. "The influence of functional ingredients on the technological properties of water-oil-swelling rubber sealing elements." Butlerov Communications 57, no. 1 (2019): 95–100. http://dx.doi.org/10.37952/roi-jbc-01/19-57-1-95.

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The article examines the influence of the nature and content of caoutchoucs, sevilen, vulcanizing group, fillers, plasticizers, directional ingredients on the technological properties (plasticity, annular modulus, density, start time of vulcanization, stickiness) of two rubber compounds. The study was conducted in order to select the basis of rubber mixtures for the manufacture of the outer and inner layers of water-oil-swellable sealing elements (SWOE) for the oil and gas extraction industry. It was established that the rubber mixture for the outer layer of SWOE on the basis of butadiene-nitr
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Egorov, Evgeny N., Nikolay F. Ushmarin, Sergey I. Sandalov, Ivan S. Spiridonov, and Nikolay I. Koltsov. "The influence of functional ingredients on the physico-mechanical and operational properties of rubbers for water-oil-swelling sealing elements." Butlerov Communications 57, no. 2 (2019): 68–73. http://dx.doi.org/10.37952/roi-jbc-01/19-57-2-68.

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The article investigated the effect of caoutchoucs, sevilen 11808-340, vulcanizing groups, fillers, plasticizers, ingredients of directional actions on the physical and mechanical properties (conditional tensile strength, elongation at break, hardness, rebound elasticity, tear resistance) and operational properties (changes of conditional tensile strength of rubbers after exposure to oil, weight changes after aging of rubbers in a solution of citric and hydrochloric acids, changes in the volume of rubbers after exposure to a mixture of oil and water) of two rubbers. These rubbers are developed
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Usmarin, Nikolay F., Andrey N. Vasilyev, Lyudmila Yu Tsareva, Tatiana A. Kirillova, and Nikolay I. Koltsov. "The investigation influence of high carbon technical filler on the properties of the plantar rubber." Butlerov Communications 57, no. 2 (2019): 74–78. http://dx.doi.org/10.37952/roi-jbc-01/19-57-2-74.

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The article investigates the influence of the high-carbon technical filler of the RP-CARBON series of three brands RP-C 100, RP-C 150 and RP-C 200, differing in the size of microparticles, on the properties of the rubber mixture which used for the manufacture of rubber shoe soles. The investigation influence of replacement of technical carbon grades TU N 330 and TU P 803 on high-carbon technical filler in the plantar rubber compound based on the combination of SKI-3 and SKMS-30ARKM-15 caoutchoucs has been investigated. The rubber mixture contained caoutchoucs, vulcanizing agent sulfur, vulcani
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Egorov, Evgeny N., Nikolay F. Ushmarin, Konstantin V. Efimov, Sergey I. Sandalov, Ivan S. Spiridonov, and Nikolay I. Koltsov. "The influence of functional ingredients on the physico-mechanical and operational properties of rubbers for water-swelling sealing elements." Butlerov Communications 58, no. 6 (2019): 152–57. http://dx.doi.org/10.37952/roi-jbc-01/19-58-6-152.

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The article investigated the effect of caoutchoucs, sevilen 11808-340, vulcanizing groups, fillers, plasticizers, directional ingredients on the physicomechanical (conditional tensile strength, elongation at break, hardness, rebound elasticity, tear resistance) and operational properties of two rubbers (changes of conditional tensile strength of rubbers after exposure to water, weight changes after aging of rubbers in a solution of citric and hydrochloric acids, changes in the volume of rubbers after exposure to water). These rubbers are developed for the manufacture of the outer and inner lay
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16

Kryuchkova, N. V., Yu N. Orlov, and S. V. Levanova. "Influence of sodium chloride concentration on the efficiency of synthetic rubber separation from SKMS-30ARK latex by poly-N,N-dimethyl-2-N-hydroxypropylammonium chloride." Russian Journal of Applied Chemistry 85, no. 2 (2012): 321–23. http://dx.doi.org/10.1134/s1070427212020280.

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Ushmarin, Nikolay F., Egor G. Efimovskii, Nina N. Petrova, Sergei I. Sandalov, and Nikolay I. Kol'tsov. "THE INFLUENCE OF POWDER SHUNGYTES ON PROPERTIES OF OIL-AND BENZO RESISTANT RUBBERS." IZVESTIYA VYSSHIKH UCHEBNYKH ZAVEDENIY KHIMIYA KHIMICHESKAYA TEKHNOLOGIYA 62, no. 1 (2018): 54–60. http://dx.doi.org/10.6060/ivkkt.20196201.5760.

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In the article two rubber mixtures are studied: rubber 7NO-68-1SK based on a combination of butadiene-nitrile caoutchouc BNKS-18AMN with chloroprene caoutchouc neoprene W and rubber 81-453 based on a combination of butadiene-nitrile caoutchouc BNKS-40AMN, butadiene caoutchouc SKD, butadiene-methylstyrene caoutchouc SKMS-30 ARK and sevilene 11808-340. The purpose of the study was to improve the physical-mechanical and operational properties of both rubber mixtures by using fine powdered schungites Taurit TS-D, Psh-5 and PSH-20 in their composition. To assess the kinetics of vulcanization of rub
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Pedrotty, Dawn M., Rebecca Y. Klinger, Nima Badie, Sara Hinds, Ara Kardashian, and Nenad Bursac. "Structural coupling of cardiomyocytes and noncardiomyocytes: quantitative comparisons using a novel micropatterned cell pair assay." American Journal of Physiology-Heart and Circulatory Physiology 295, no. 1 (2008): H390—H400. http://dx.doi.org/10.1152/ajpheart.91531.2007.

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Well-controlled studies of the structural and functional interactions between cardiomyocytes and other cells are essential for understanding heart pathophysiology and for the further development of safe and efficient cell therapies. We established a novel in vitro assay composed of a large number of individual micropatterned cell pairs with reproducible shape, size, and region of cell-cell contact. This assay was applied to quantify and compare the frequency of expression and distribution of electrical (connexin43) and mechanical (N-cadherin) coupling proteins in 5,000 cell pairs made of cardi
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Alejandro Lerman, Daniel, Nasri Alotti, Kiddy Levente Ume, and Bruno Péault. "Cardiac Repair and Regeneration: The Value of Cell Therapies." European Cardiology Review 11, no. 1 (2016): 43. http://dx.doi.org/10.15420/ecr.2016:8:1.

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Ischaemic heart disease is the predominant contributor to cardiovascular morbidity and mortality; one million myocardial infarctions occur per year in the USA, while more than five million patients suffer from chronic heart failure. Recently, heart failure has been singled out as an epidemic and is a staggering clinical and public health problem associated with significant mortality, morbidity and healthcare expenditures, particularly among those aged ≥ 65 years. Death rates have improved dramatically over the last four decades, but new approaches are nevertheless urgently needed for those pat
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Efimov, Konstantin V., Lyudmila Yu Tsareva, Nikolay F. Ushmarin, and Nikolay I. Koltsov. "Influence of magnesium hydrosilicate on the properties plantar rubber." Butlerov Communications 61, no. 1 (2020): 91–95. http://dx.doi.org/10.37952/roi-jbc-01/20-61-1-91.

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The properties of rubber products are determined by the nature and content of caoutchoucs, vulcanizing systems and other ingredients. Among them, fillers play an important role. The most common fillers are carbon black and silicas. Recently, in connection with the increasing operational requirements for rubber products, additives of special fillers began to be introduced into rubber mixtures. Among them, silicates are of practical interest, the use of which allows not only to reduce the cost, but also to give qualitatively new useful physical and mechanical properties to rubbers. Improving the
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Kumar, Narendra, and Sushil Kumar. "Evidence of multifaceted SKS/SKKS splitting directions in the Sikkim Himalaya, India." Journal of Geodynamics 117 (June 2018): 12–20. http://dx.doi.org/10.1016/j.jog.2018.02.003.

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Reiss, M. C., M. D. Long, and N. Creasy. "Lowermost Mantle Anisotropy Beneath Africa From Differential SKS ‐ SKKS Shear‐Wave Splitting." Journal of Geophysical Research: Solid Earth 124, no. 8 (2019): 8540–64. http://dx.doi.org/10.1029/2018jb017160.

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Long, Maureen D. "Complex anisotropy in D″ beneath the eastern Pacific from SKS–SKKS splitting discrepancies." Earth and Planetary Science Letters 283, no. 1-4 (2009): 181–89. http://dx.doi.org/10.1016/j.epsl.2009.04.019.

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Elizabeth, Vanacore, and Niu Fenglin. "Characterization of the D″ beneath the Galapagos Islands using SKKS and SKS waveforms." Earthquake Science 24, no. 1 (2011): 87–99. http://dx.doi.org/10.1007/s11589-011-0772-8.

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Karaseva, Yu S., E. N. Cherezova, L. A. Kuvshinova, and E. V. Udoratina. "The Use of Destructed Waste Cardboard for Increasing of Adhesion Strength and Thermo Oxidative Stability of Vulcanized Rubbers Based on (Alpha-Methyl)-Styrene Butadiene Rubber SKMS-30 ARKM-15." Kauchuk i Rezina 79, no. 3 (2020): 140–45. http://dx.doi.org/10.47664/0022-9466-2020-79-3-140-145.

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Wieland, S. J., Q. H. Gong, J. E. Fletcher, and H. Rosenberg. "Altered sodium current response to intracellular fatty acids in halothane-hypersensitive skeletal muscle." American Journal of Physiology-Cell Physiology 271, no. 1 (1996): C347—C353. http://dx.doi.org/10.1152/ajpcell.1996.271.1.c347.

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Biopsies of human skeletal muscle were analyzed by an in vitro contracture test (IVCT) for responsiveness to a halothane challenge: noncontracting (nonresponsive; IVCT-) and contracting (IVCT+). A muscle biopsy that is IVCT+ indicates potential malignant hyperthermia (MH) susceptibility. Primary cultures were grown from portions of the skeletal muscle biopsies, and voltage-activated currents were measured by whole cell recording in the presence or absence of 2-5 microM intracellular arachidonic or oleic acids. In untreated IVCT- cells, Na+ currents were predominantly tetrodotoxin (TTX) insensi
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de Hoop-Sommen, MA, TM van der Zanden, K. Allegaert, et al. "P26 Pilot on harmonising dosing recommendation for term and preterm neonates in the Netherlands (Neodose project)." Archives of Disease in Childhood 104, no. 6 (2019): e27.2-e28. http://dx.doi.org/10.1136/archdischild-2019-esdppp.64.

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BackgroundMany drugs are used off-label in term and preterm neonates, and dosing recommendations for many drugs are lacking in the Dutch Paediatric Formulary (DPF). This results in widely varying dosing regimens used across neonatal intensive care units (NICUs) in the Netherlands. The Neodose pilot project aimed to develop best-evidence national dosing recommendations for (pre)term neonates. Because scientific evidence is scarce, a consensus-based approach was used.MethodsA priority drug list, containing the most frequently used drugs for neonates, was drafted. From this list 22 drugs were sel
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Hall, Stéphen A., J. M. Kendall, and Mirko van der Baan. "Some comments on the effects of lower-mantle anisotropy on SKS and SKKS phases." Physics of the Earth and Planetary Interiors 146, no. 3-4 (2004): 469–81. http://dx.doi.org/10.1016/j.pepi.2004.05.002.

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Özalaybey, Serdar, and Wang-Ping Chen. "Frequency-dependent analysis of SKS/SKKS waveforms observed in Australia: evidence for null birefringence." Physics of the Earth and Planetary Interiors 114, no. 3-4 (1999): 197–210. http://dx.doi.org/10.1016/s0031-9201(99)00058-8.

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Schweitzer, J., and G. Müller. "Anomalous difference traveltimes and amplitude ratios of SKS and SKKS from Tonga-Fiji Events." Geophysical Research Letters 13, no. 13 (1986): 1529–32. http://dx.doi.org/10.1029/gl013i013p01529.

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Lutz, Katherine A., Maureen D. Long, Neala Creasy, and Jie Deng. "Seismic anisotropy in the lowermost mantle beneath North America from SKS-SKKS splitting intensity discrepancies." Physics of the Earth and Planetary Interiors 305 (August 2020): 106504. http://dx.doi.org/10.1016/j.pepi.2020.106504.

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Roy, Sunil K., Ravi Kumar M., and Srinagesh D. "Upper and lower mantle anisotropy inferred from comprehensive SKS and SKKS splitting measurements from India." Earth and Planetary Science Letters 392 (April 2014): 192–206. http://dx.doi.org/10.1016/j.epsl.2014.02.012.

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He, Xiaobo, and Maureen D. Long. "Lowermost mantle anisotropy beneath the northwestern Pacific: Evidence from PcS, ScS, SKS, and SKKS phases." Geochemistry, Geophysics, Geosystems 12, no. 12 (2011): n/a. http://dx.doi.org/10.1029/2011gc003779.

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Ayşe Nida KURT and Uğur Başaran. "Tokat Ekolojik Şartlarında Bazı Tek Yıllık Çim (Lolium multiflorum Lam.) Çeşitlerinin Adaptasyonu." ISPEC Journal of Agricultural Sciences 5, no. 2 (2021): 296–305. http://dx.doi.org/10.46291/ispecjasvol5iss2pp296-305.

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Bu çalışma bazı tek yıllık çim (Lolium multiflorum Lam.) çeşitlerinin Tokat ekolojik şartlarına uyumunu belirlemek amacıyla 2018-2019 yetiştirme sezonunda yürütülmüştür. Çalışmada 11 adet tek yıllık çim çeşidi (Barmultra II, Barspectra II, Bartigra, Baqueano, Caramba, Devis 2017, Pollanum, Trinova, Vallivert, Venüs, Vespolini 2016) kullanılmıştır. Deneme Tokat Merkeze bağlı Bakışlı Köyünde, çiftçi koşullarında, tesadüf blokları deneme desenine göre 3 tekrarlı olarak yürütülmüştür. Ekim işlemi 2018 sonbaharında 20 cm sıra aralığında ve her çeşitten 3 kg da-1 olacak şekilde elle yapılmıştır. Has
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Lee, Janghaeng, Mehrzad Samadi, Yongjun Park, and Scott Mahlke. "SKMD." ACM Transactions on Computer Systems 33, no. 3 (2015): 1–27. http://dx.doi.org/10.1145/2798725.

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Nosek, M. T., and J. A. J. Martyn. "Na+ channel and acetylcholine receptor changes in muscle at sites distant from burns do not simulate denervation." Journal of Applied Physiology 82, no. 4 (1997): 1333–39. http://dx.doi.org/10.1152/jappl.1997.82.4.1333.

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Nosek, M. T., and J. A. J. Martyn.Na+ channel and acetylcholine receptor changes in muscle at sites distant from burns do not simulate denervation. J. Appl. Physiol. 82(4): 1333–1339, 1997.—Muscle weakness and aberrant responses to neuromuscular relaxants after burn injury are associated with upregulation of acetylcholine receptors (AChRs). Typically, these functional, pharmacological, and biochemical changes occur after denervation, in which transcriptionally mediated qualitative changes in AChRs and Na+ channels and of myogenic regulatory proteins MyoD and myogenin also occur. This study in
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Tiwari, Ashwani Kant, Kirti Bhushan, Tuna Eken, and Arun Singh. "Upper mantle dynamics of Bangladesh by splitting analysis of core-mantle refracted SKS, PKS, and SKKS phases." Physics of the Earth and Planetary Interiors 279 (June 2018): 21–32. http://dx.doi.org/10.1016/j.pepi.2018.03.006.

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Graw, Jordan H., and Samantha E. Hansen. "Upper mantle seismic anisotropy beneath the Northern Transantarctic Mountains, Antarctica from PKS, SKS, and SKKS splitting analysis." Geochemistry, Geophysics, Geosystems 18, no. 2 (2017): 544–57. http://dx.doi.org/10.1002/2016gc006729.

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Truong, Jonas, Marius Bulota, and Alexis Lussier Desbiens. "Historical Trends in Alpine Ski Design: How Skis Have Evolved Over the Past Century." Proceedings 49, no. 1 (2020): 135. http://dx.doi.org/10.3390/proceedings2020049135.

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Alpine skis have changed dramatically in the last century. Long and straight wood skis have evolved into shorter lengths and now contain a plethora of modern materials. Shaped skis have become the norm. Today’s skis also offer a variety of waist widths and shapes to cater to specific uses. By studying how skis have evolved, it is possible to gain insight into how the design of alpine skis has progressed. To do so, the mechanical properties of 1016 skis, from the 1920s to 2019, were measured with a machine developed at the University of Sherbrooke. The resulting data are used to calculate vario
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Silver, Paul G., and Craig Bina. "An anomaly in the amplitude ratio of SKKS/SKS in the range 100-108° from portable teleseismic data." Geophysical Research Letters 20, no. 12 (1993): 1135–38. http://dx.doi.org/10.1029/92gl02464.

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Deng, Jie, Maureen D. Long, Neala Creasy, et al. "Lowermost mantle anisotropy near the eastern edge of the Pacific LLSVP: constraints from SKS–SKKS splitting intensity measurements." Geophysical Journal International 210, no. 2 (2017): 774–86. http://dx.doi.org/10.1093/gji/ggx190.

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Souriau, Annie, and Georges Poupinet. "A study of the outermost liquid core using differential travel times of the SKS, SKKS and S3KS phases." Physics of the Earth and Planetary Interiors 68, no. 1-2 (1991): 183–99. http://dx.doi.org/10.1016/0031-9201(91)90017-c.

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Gim, Jinsu, Joohyeong Jeon, Bongju Kim, Taejoon Jeong, Kyeonghyeon Jeon, and Byungohk Rhee. "Quantification and design of jumping-ski characteristics." Proceedings of the Institution of Mechanical Engineers, Part P: Journal of Sports Engineering and Technology 232, no. 2 (2017): 150–59. http://dx.doi.org/10.1177/1754337117721831.

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Elastic and dynamic characteristics of jumping-skis affect ski performance at all four ski jumping phases. Compared with the number of studies on alpine-skis, there have been few studies on the characteristics of jumping-skis. This article identifies design parameters that have the most influence on jumping-ski characteristics. To identify the elastic and dynamic characteristics of jumping-skis, previous research and testing methods for alpine-skis were modified. Spring constants and bending stiffness distributions for three jumping-skis were measured. Natural frequencies, modal shapes, and da
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Mao, Duo, Xinpeng Yao, Guowei Feng, et al. "Skin-Derived Precursor Cells Promote Angiogenesis and Stimulate Proliferation of Endogenous Neural Stem Cells after Cerebral Infarction." BioMed Research International 2015 (2015): 1–10. http://dx.doi.org/10.1155/2015/945846.

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Stroke is one of the most common diseases that caused high mortality and has become burden to the health care systems. Stem cell transplantation has shown therapeutic effect in ameliorating ischemic damage after cerebral artery occlusion mainly due to their neurogenesis, immune regulation, or effects on the plasticity, proliferation, and survival of host cells. Recent studies demonstrated that skin-derived precursor cells (SKPs) could promote central nervous system regeneration in spinal cord injury model or the neonatal peripheral neuron. Here, we investigated the therapeutic potential of SKP
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Virmavirta, Mikko, Juha Kivekäs, and Paavo Komi. "Ski Jumping Takeoff in a Wind Tunnel With Skis." Journal of Applied Biomechanics 27, no. 4 (2011): 375–79. http://dx.doi.org/10.1123/jab.27.4.375.

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The effect of skis on the force–time characteristics of the simulated ski jumping takeoff was examined in a wind tunnel. Takeoff forces were recorded with a force plate installed under the tunnel floor. Signals from the front and rear parts of the force plate were collected separately to examine the anteroposterior balance of the jumpers during the takeoff. Two ski jumpers performed simulated takeoffs, first without skis in nonwind conditions and in various wind conditions. Thereafter, the same experiments were repeated with skis. The jumpers were able to perform very natural takeoff actions (
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Biernaskie, Jeff, and Freda D. Miller. "White Matter Repair: Skin-Derived Precursors as a Source of Myelinating Cells." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 37, S2 (2010): S34—S41. http://dx.doi.org/10.1017/s0317167100022411.

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ABSTRACT:Stem cell based therapies hold great promise for repair and functional restoration following neurological injury and disease. Skin-derived precursors (or “SKPs”) are a novel, multipotent somatic stem cell that resides within the mammalian dermis. SKPs persist within the skin throughout adulthood and yet intriguingly, exhibit many similarities to embryonic neural crest stem cells (NCSCs). For example, SKPs give rise to both neural and mesodermal cell types, and the former appear biased to peripheral nervous system fates. As such, SKPs are capable of generating Schwann cells, the myelin
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Ke, Tingyu, Mei Yang, Duo Mao, et al. "Co-Transplantation of Skin-Derived Precursors and Collagen Sponge Facilitates Diabetic Wound Healing by Promoting Local Vascular Regeneration." Cellular Physiology and Biochemistry 37, no. 5 (2015): 1725–37. http://dx.doi.org/10.1159/000438537.

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Background/Aims: Impaired diabetes wound healing can often lead to serious complications and remains a major health concern due to the lack of effective therapeutic approaches. Compromised angiogenesis, disrupted growth factor and cytokine activity are all attributable to diabetic wound healing impairment. The skin-derived precursors (SKPs) have been shown to differentiate into vascular and nerve cells, both of which are crucial components for wound repair. Given their easy accessibility and multipotency, the SKPs were proposed as an ideal therapeutic candidate for diabetic wound healing. Sinc
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Zhong, Jianqiao, and Li Li. "Skin-Derived Precursors against UVB-Induced Apoptosis via Bcl-2 and Nrf2 Upregulation." BioMed Research International 2016 (2016): 1–11. http://dx.doi.org/10.1155/2016/6894743.

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Bcl-2 and Nrf2 are critical factors in protecting cells against UVB-induced apoptosis. Hair-follicle-bulge stem cells could resist ionization through Bcl-2 upregulation. Skin-derived precursors (SKPs) dwelling on the bulge may be against UVB irradiation. Initially, SKPs were isolated and identified. Then, SKPs were exposed to UVB and grew in medium for 24 hours. CCK-8 assay, TUNEL, and Ki67 staining evaluated cells apoptosis/proliferation, while SA-βgal staining evaluated cells senescence and pH2AX immunostaining evaluated DNA damage. Meanwhile, Bcl-2, Nrf2, HO-1, Bax, and Bak expressions were
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Aydin Keskin, Gulsen, and Coskun Ozkan. "Multiple Criteria ABC Analysis with FCM Clustering." Journal of Industrial Engineering 2013 (December 18, 2013): 1–7. http://dx.doi.org/10.1155/2013/827274.

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The number of stock keeping units (SKUs) possessed by organizations can easily reach quite a few. An inventory management policy for each individual SKU is not economical to design. ABC analysis is one of the conventionally used approaches to classify SKUs. In the classical method, the SKUs are ranked with respect to the descending order of the annual dollar usage, which is the product of unit price and annual demand. The few of the SKUs that have the highest annual dollar usage are in group A and should be taken into account mostly; the SKUs with the least annual dollar usage are in group C a
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Wang, Jinmei, Xiaoxiao Wang, Jundong Xie, et al. "Engineered Skin Substitute Regenerates the Skin with Hair Follicle Formation." Biomedicines 9, no. 4 (2021): 400. http://dx.doi.org/10.3390/biomedicines9040400.

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Currently, engineered skin substitutes (ESS) are unable to regenerate cutaneous appendages. Recent studies have shown that skin-derived precursors (SKPs), which are extensively available, have the potential to induce hair follicle neogenesis. Here, we demonstrate that ESS consisting of culture-expanded SKPs and epidermal stem cells (Epi-SCs) reconstitute the skin with hair follicle regeneration after grafting into nude mice. SKPs seeded in a C-GAG matrix proliferated and expressed higher levels of hair induction signature genes—such as Akp2, Sox2, CD133 and Bmp6—compared to dermal fibroblasts.
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