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Relevant bibliographies by topics / Skull Base Neoplasms – surgery

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Academic literature on the topic 'Skull Base Neoplasms – surgery'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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Journal articles on the topic "Skull Base Neoplasms – surgery"

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Donald, Paul J., Bernard M. Lyons, and Joao J. Maniglia. "Surgery of the Skull Base for Head and Neck Neoplasms." Otolaryngology–Head and Neck Surgery 112, no. 5 (May 1995): P88. http://dx.doi.org/10.1016/s0194-5998(05)80206-2.

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Educational objectives: To understand the relationship of deep facial structures to the cranial base and the pertinent intracranial anatomy; to perform the comprehensive workup required by skull base surgery patients; and to acquire a working knowledge of the basic skull base procedures in the anterior, middle, and posterior cranial fossa.

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Marzo, Sam J., John P. Leonetti, and Guy Petruzzelli. "Facial paralysis caused by malignant skull base neoplasms." Neurosurgical Focus 12, no. 5 (May 2002): 1–4. http://dx.doi.org/10.3171/foc.2002.12.5.3.

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Object Bell palsy remains the most common cause of facial paralysis. Unfortunately, this term is often erroneously applied to all cases of facial paralysis. Methods The authors performed a retrospective review of data obtained in 11 patients who were treated at a university-based referral practice between July 1988 and September 2001 and who presented with acute facial nerve paralysis mimicking Bell palsy. All patients were subsequently found to harbor an occult skull base neoplasm. A delay in diagnosis was demonstrated in all cases. Seven patients died of their disease, and four patients are currently free of disease. Conclusions Although Bell palsy remains the most common cause of peripheral facial nerve paralysis, patients in whom neoplasms invade of the facial nerve may present with acute paralysis mimicking Bell palsy that fails to resolve. Delays in diagnosis and treatment in such cases may result in increased rates of mortality and morbidity.

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DiNardo, Laurence J., and Robert L. Rumsey. "Management of Malignant Schwannomas of the Paranasal Sinuses and Anterior Skull Base." Ear, Nose & Throat Journal 75, no. 6 (June 1996): 377–80. http://dx.doi.org/10.1177/014556139607500612.

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The evolution of skull base surgery has facilitated the extirpation of previously unresectable tumors. As experience with skull base surgery increases, the feasibility of resection and long-term outcomes is becoming apparent for the more common lesions. Neoplasms such as malignant schwannomas are rare and, therefore, defy single-institution analysis. The treatment and four-year follow-up of a malignant paranasal sinus and anterior skull base schwannoma is described. Analysis of the literature confirms the low incidence of this tumor and supports the efficacy of skull base surgery in its treatment.

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Nikonova, Svetlana Dmitrievna, Maksim Aleksandrovich Kutin, Elizaveta Vladimirovna Shelesko, Pavel Lvovich Kalinin, Nadezhda Alekseevna Chernikova, and Lyudmila Aleksandrovna Fomochkina. "Recovery peculiarities and complications in the nasal cavity caused by skull base reconstruction with nasoseptal flap after transnasal removal of chiasmo-sellar mass lesions." Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery), no. 1 (January 1, 2021): 36–44. http://dx.doi.org/10.33920/med-01-2101-03.

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Today, endoscopic endonasal approach is considered the gold standard in skull base surgery of the chiasmosellar region. Advances in transnasal endoscopic skull base surgery allow conducting more extensive interventions via wider approaches which requires more complicated plastic closure of the skull base defect. In 2006, G. Haddad et al. suggested using a vascularized nasoseptal flap to reconstruct a skull base defect. This method is generally accepted at present due to its reliability and low frequency of postoperative complications. The purpose of this article is to analyze publications on possible complications and pathological conditions of the nasal cavity when using a vascularized nasoseptal flap for skull base surgery after removal of neoplasms of the chiasmo-sellar region. The study included articles found in the Pubmed database (2006–2020) which described frequency and character of complications caused by skull base defect reconstruction by a nasoseptal flap after transnasal removal of chiasmo-sellar neoplasms. According to the literature review, the following complications are reported: cerebrospinal fluid leak, flap necrosis and infectious complications, pathological changes in the nasal cavity: prolonged crusting, synechiae, epistaxis, septum perforation, sinusitis, subatrophic changes of mucosae, nasolacrimal duct obstruction, olfactory dysfunction. The authors conclude that the nasoseptal flap is, undoubtedly, an effective material for reconstruction of dural defects by endoscopic endonasal skull base surgery, because of its good viability due to the preserved blood supply and high tightness of the plasty. However, there is a risk of complications in the nasal cavity. For these reasons, development of effective methods for prevention of nasal complications after using a vascularized flap in endoscopic endonasal surgery is an important issue today.

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Tabaee, Abtin, Gurston Nyquist, Vijay K. Anand, Ameet Singh, Ashutosh Kacker, and Theodore H. Schwartz. "Palliative Endoscopic Surgery in Advanced Sinonasal and Anterior Skull Base Neoplasms." Otolaryngology–Head and Neck Surgery 142, no. 1 (January 2010): 126–28. http://dx.doi.org/10.1016/j.otohns.2009.09.021.

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Schirmer, Clemens M., and Carl B. Heilman. "Hemangiopericytomas of the skull base." Neurosurgical Focus 30, no. 5 (May 2011): E10. http://dx.doi.org/10.3171/2011.2.focus119.

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Object Intracranial hemangiopericytomas are frequently located along the dural sinuses along the skull base and represent rare, aggressive CNS neoplasms that are difficult to distinguish from meningiomas based on both imaging and gross characteristics. The authors of this study describe 3 patients with these lesions and review the pertinent literature. Methods Two men and 1 woman, whose median age at the time of the initial presentation was 37 years (range 20–53 years), constitute this series. They underwent multimodal treatment consisting of resection, embolization, radiation therapy, and in 1 case chemotherapy. Results Two of the 3 patients treated were alive after a mean follow-up of 93 months (range 4–217 months). One patient died 217 months after the initial diagnosis. The longest tumor progression–free interval after the initial or secondary resection was 43 months (range 4–84 months). Conclusions Hemangiopericytomas have been reclassified as mesenchymal nonmeningothelial tumors. They have an inevitable tendency to recur locally and metastasize distally. The mainstay of therapy remains an aggressive attempt to achieve gross-total resection at the initial surgery. Postoperative adjuvant radiotherapy should be offered to all patients, regardless of the degree of resection achieved. Diligent long-term follow-up is paramount as local recurrences and distal metastases can develop sometimes years after the initial treatment.

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Kanamori, Hiroki, Yohei Kitamura, Tokuhiro Kimura, Kazunari Yoshida, and Hikaru Sasaki. "Genetic characterization of skull base chondrosarcomas." Journal of Neurosurgery 123, no. 4 (October 2015): 1036–41. http://dx.doi.org/10.3171/2014.12.jns142059.

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OBJECT Although chondrosarcomas rarely arise in the skull base, chondrosarcomas and chordomas are the 2 major malignant bone neoplasms occurring at this location. The distinction of these 2 tumors is important, but this distinction is occasionally problematic because of radiological and histological overlap. Unlike chordoma and extracranial chondrosarcoma, no case series presenting a whole-genome analysis of skull base chondrosarcomas (SBCSs) has been reported. The goal of this study is to clarify the genetic characteristics of SBCSs and contrast them with those of chordomas. METHODS The authors analyzed 7 SBCS specimens for chromosomal copy number alterations (CNAs) using comparative genomic hybridization (CGH). They also examined IDH1 and IDH2 mutations and brachyury expression. RESULTS In CGH analyses, the authors detected CNAs in 6 of the 7 cases, including chromosomal gains of 8q21.1, 19, 2q22-q32, 5qcen-q14, 8q21-q22, and 15qcen-q14. Mutation of IDH1 was found with a high frequency (5 of 7 cases, 71.4%), of which R132S was most frequently mutated. No IDH2 mutations were found, and immunohistochemical staining for brachyury was negative in all cases. CONCLUSIONS To the best of the authors' knowledge, this is the first whole-genome study of an SBSC case series. Their findings suggest that these tumors are molecularly consistent with a subset of conventional central chondrosarcomas and different from skull base chordomas.

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Chaitanya, S. H., C. Basker Rao, and G. Krishnan. "Transfacial approaches in the management of anterior and middle skull base neoplasms." International Journal of Oral and Maxillofacial Surgery 36, no. 11 (November 2007): 997. http://dx.doi.org/10.1016/j.ijom.2007.08.077.

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Boyle, Jay O., Kinner C. Shah, and Jatin P. Shah. "Craniofacial resection for malignant neoplasms of the skull base: An overview." Journal of Surgical Oncology 69, no. 4 (December 1998): 275–84. http://dx.doi.org/10.1002/(sici)1096-9098(199812)69:4<275::aid-jso13>3.0.co;2-1.

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Carpenter, Patrick S., Ryan C. Burgette, John P. Leonetti, and Sam J. Marzo. "Auricular Complications in Parotid, Temporal Bone, Infratemporal Fossa, and Lateral Skull Base Surgery." Ear, Nose & Throat Journal 96, no. 2 (February 2017): E27—E31. http://dx.doi.org/10.1177/014556131709600216.

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Neoplasms located in the parotid region, temporal bone, infra-temporal fossa, and lateral skull base represent a challenge due to their difficult anatomic location and surrounding neurovascular structures. A variety of surgical approaches are appropriate to access this area, although several of them can place the auricular blood supply in danger. If the auricular blood supply is compromised, ischemia and, eventually, avascular necrosis of the auricle can occur. Auricular necrosis often can cause patients a delay in adjuvant radiation therapy and result in the need for additional reconstructive procedures. There-fore, it is imperative to identify risk factors associated with the development of this disabling complication. We conducted a retrospective review of 32 individuals undergoing treatment of benign and malignant lesions in the parotid gland, infratemporal fossa, and lateral skull base. To identify potential risk factors for auricular necrosis, the patients were analyzed based on the type of neoplasm (malignant or benign), risk factors affecting blood flow (diabetes mellitus, smoking history, prior radiation, prior surgery), body mass index, and the length of surgery. In our population examined, 3 instances of auricular necrosis occurred. None of the potential risk factors proved to be statistically significant (although malignant pathology approached significance at p = 0.07). Two of the patients required an auriculectomy with reconstruction. The third had multiple postoperative clinic visits for surgical debridement. Although no potential risk factors were statistically significant, surgeons should remain cognizant of the auricular blood supply while performing surgery via preauricular and postauricular approaches to this area.

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Dissertations / Theses on the topic "Skull Base Neoplasms – surgery"

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Mourad, Mohammed [Verfasser], and Marcos [Akademischer Betreuer] Tatagiba. "Endoscopic assisted surgery of posterior skull base. Analysis of the advantages / Mohammed Mourad ; Betreuer: Marcos Tatagiba." Tübingen : Universitätsbibliothek Tübingen, 2017. http://d-nb.info/1199615145/34.

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HASHIZUME, CHISA, TATSUYA KOBAYASHI, YUTA SHIBAMOTO, TAKAHIKO TSUGAWA, MASAHIRO HAGIWARA, YOSHIMASA MORI, and HISATO NAKAZAWA. "Useful Base Plate to Support the Head During Leksell Skull Frame Placement in Gamma Knife Perfexion Radiosurgery." Nagoya University School of Medicine, 2014. http://hdl.handle.net/2237/19481.

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Santamaría, Gadea Alfonso. "Uso endoscópico del colgajo pericraneal para la reconstrucción nasal y de base de cráneo." Doctoral thesis, Universitat de Barcelona, 2018. http://hdl.handle.net/10803/663441.

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INTRODUCCIÓN: El colgajo pericraneal (CP) ha sido habitualmente utilizado en las reconstrucciones cráneo faciales y de base de cráneo. Su utilidad en los abordajes abiertos se encuentra ampliamente descrita en la literatura. Sin embargo, el avance de las técnicas endoscópicas ha relegado el uso del CP por el de los colgajos endonasales. Al mismo tiempo, este avance representa una oportunidad para ampliar las indicaciones del CP a aquellos abordajes endoscópicos en los que los colgajos endonasales no se encuentren disponibles. OBJETIVO: Este trabajo tiene como objetivo estudiar y analizar el uso del CP en la reconstrucción endoscópica de base de cráneo y del septum nasal. MATERIALES Y MÉTODOS: Se realiza un estudio en tres áreas: 1. Se realiza un estudio anatómico en cadáver fresco en el que se ejecutan reconstrucciones de los distintos abordajes de base de cráneo (abordaje transcribiforme, abordaje transplanum, abordaje clival y abordaje de la unión cráneo-vetebral) y del septum nasal. En todos los especímenes, tras recrear el defecto que se a reconstruir, se realizar una disección clásica del CP y posteriormente se introduce a través de una osteotomía del seno frontal. Por último con un manejo endoscópico se realiza la reconstrucción del defecto. 2. En segundo lugar, se realiza un análisis radiológico en tomografías computerizadas (TC) de los límites de reconstrucción que permite el CP y la estandarización del tamaño del mismo según el defecto que se vaya a reconstruir. Se toma como referencia la pared posterior del conducto auditivo interno. 3. Posteriormente, se realiza un estudio clínico en pacientes con tumores de base de cráneo y perforación septal total en los que no existen opciones reconstructivas endonasales o estas no alcanzan el tamaño suficiente. En ellos, se realiza una reconstrucción endoscópica con CP de sus defectos. RESULTADOS: Las mediciones anatómicas mostraron que el tabique nasal tiene una longitud media de 5,8 ± 0,7 cm, mientras que el colgajo pericraneal presenta un promedio de 18,4 ± 1,3; 18,3 ± 1,3 cm de largo (área media 121,6 ± 17,7; 121,5 ± 19,4 cm2). En todos los especímenes se logró la reconstrucción total de los defectos. En el estudio radiológico, se determinó que para reconstruir defectos secundarios a abordajes transcribriforme, transtuberculum, clival y craneovertebrales, la incisión distal del colgajo pericraneal debe colocarse respectivamente a -3,7 ± 2,0 cm (ángulo -17,4 ± 8,5º), -0,2 ± 2,0 cm (ángulo -1,0 ± 9,3º), +5,5 ± 2,3 cm (ángulo +24,4 ± 9,7º), +8,4 ± 2,4 cm (ángulo +36,6 ± 11,5º), en relación con el punto de referencia. En el caso de la reconstrucción septal, las mediciones radiológicas revelaron que el área del colgajo pericraneal necesaria para reconstruir una perforación septal total sería de 40,9 ± 4,2 cm2, teniendo en cuenta un 30% adicional por la posible retracción durante la cicatrización. Para la reparación total del tabique, el borde distal del colgajo pericraneal debe situarse a 0,8 ± 2,0 cm (3,4 ± 8,78º) del punto de referencia (proyección vertical del canal auditivo externo). Los defectos de la base del cráneo (n = 6) y de la perforación septal total (n=1) en nuestra cohorte clínica se reconstruyeron completamente sin complicaciones. CONCLUSIONES: Este trabajo concluye que el CP presenta un área suficiente para la reconstrucción endoscópica de los distintos abordajes de base de cráneo y septal total. El uso del seno frontal como puerta de entrada a las fosa nasales y el manejo endoscópico del CP en las reconstrucciones es una técnica factible y simple.
The pericranial flap (PCF) has been commonly used in craneo-facial and skull base reconstructions. However, the advance of endoscopic techniques has relegated the use of PCF. At the same time, this advance represents an opportunity to extend the indications of the PCF to those endoscopic approaches in which the endonasal flaps are not available. The aims of this study is to analyze the use of the PCF in the endoscopic reconstruction of the skull base and the nasal septum. An anatomical study on fresh cadaver specimens in which reconstructions of the different skull base defects and nasal septum were carried out. The PCF was introduced through an osteotomy of the frontal sinus. Then, the defects were endoscopically repair. A radiological analysis in computed tomography was performed. The reconstruction limits allowed by the PCF and the standardization of the size of the PCF according to the defect were measured. A clinical study is performed in patients with tumors of the skull base and total septal perforation. In the anatomical study, the nasal septum length and the PCF length and area were obtained. In all the specimens, the total reconstruction of the defects was achieved. The radiological study determined that to reconstruct defects secondary to transcribriform, transtuberculum, clival and craniovertebral approaches, the distal incision of the PCF should be placed respectively at -3.7 ± 2.0 cm, -0,2 ± 2,0 cm, +5,5 ± 2,3 cm, +8,4 ± 2.4 cm, from the reference point (external auditory canal). For total repair of the septum, the distal edge of the PCF should be located 0.8 ± 2.0 cm from the reference point. Defects of the skull base (n = 6) and total septal perforation (n = 1) in our clinical cohort were completely reconstructed. This work concludes that the CP presents enough area for the endoscopic reconstruction of the different approaches of the skull base and total septal perforation. The use of the frontal sinus as the entrance and the endoscopic management of the CP in the reconstructions is a feasible and simple technique.

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"Surgical Freedom in Endoscopic Skull Base Surgery: Quantitative Analysis for Endoscopic Approaches." Doctoral diss., 2014. http://hdl.handle.net/2286/R.I.24890.

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abstract: During the past five decades neurosurgery has made great progress, with marked improvements in patient outcomes. These noticeable improvements of morbidity and mortality can be attributed to the advances in innovative technologies used in neurosurgery. Cutting-edge technologies are essential in most neurosurgical procedures, and there is no doubt that neurosurgery has become heavily technology dependent. With the introduction of any new modalities, surgeons must adapt, train, and become thoroughly familiar with the capabilities and the extent of application of these new innovations. Within the past decade, endoscopy has become more widely used in neurosurgery, and this newly adopted technology is being recognized as the new minimally invasive future of neurosurgery. The use of endoscopy has allowed neurosurgeons to overcome common challenges, such as limited illumination and visualization in a very narrow surgical corridor; however, it introduces other challenges, such as instrument "sword fighting" and limited maneuverability (surgical freedom). The newly introduced concept of surgical freedom is very essential in surgical planning and approach selection and can play a role in determining outcome of the procedure, since limited surgical freedom can cause fatigue or limit the extent of lesion resection. In my thesis, we develop a consistent objective methodology to quantify and evaluate surgical freedom, which has been previously evaluated subjectively, and apply this model to the analysis of various endoscopic techniques. This model is crucial for evaluating different endoscopic surgical approaches before they are applied in a clinical setting, for identifying surgical maneuvers that can improve surgical freedom, and for developing endoscopic training simulators that accurately model the surgical freedom of various approaches. Quantifying the extent of endoscopic surgical freedom will also provide developers with valuable data that will help them design improved endoscopes and endoscopic instrumentation.
Dissertation/Thesis
Ph.D. Neuroscience 2014

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Cho, Der-Yang, and 周德陽. "Cost Evaluation of Open Surgery and Gamma Knife Radiosurgery for Benign Skull Base Tumors." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/77548979206967782049.

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碩士
臺中健康暨管理學院
健康管理研究所
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Objective: The aim of this study was to evaluate the relative costs of benign skull base tumors treated with open surgery and gamma knife radiosurgery. Materials and Methods: In a retrospective study in China Medical University Hospital, we studied 174 patients with benign skull base tumors, less than 3 cm in diameter (or volume less than 30 ml), admitted in the past 4 years. Group A (n=94) underwent open surgery for removal of the tumors while group B (n=80) underwent gamma knife radiosurgery. The total costs were evaluated by both direct and indirect cost. The direct costs comprised intensive care unit (ICU) cost, ward cost, operating room (OR) cost, and outpatient visiting cost. The indirect costs included workless cost and mortality cost. The length of hospital stay, the length of workless day, surgical complications, mortality, and cost-effectiveness were calculated too. Student t-test and Chi-square test were employed for statistical analysis. Results: The mean length of hospital stay for open surgery was 18.2 ±30.4 days including 5.0 ±14.7 days of ICU stay and 13.0 ±15.2 days of ward stay. The mean hospital stay for gamma knife was 2.2 ±0.9 days with no need of ICU stay, (open surgery vs. gamma knife, P<0.01). The mean workless day for open surgery was 119 ±142 days and 7.6 ±6.4 days for gamma knife, (open surgery vs. gamma knife, P<0.01). The gamma knife cost per hour (1,435 USD) is higher than the open surgery cost per hour (450 USD), P<0.01. The direct cost for gamma knife (9,460 ±6,691 USD) is higher than that for open surgery (5,530 ±5,597 USD), P<0.01. The hospital benefit was more of a negative balance for gamma knife (-4,830 ±4,263 USD) than for open surgery (-960 ± 5,325 USD), P<0.05. Open surgery had more complication rates (31.2%) than gamma knife (3.8%). Open surgery had a mortality rate of 5.3%; there was no mortality for gamma knife. The indirect costs, including workless cost and mortality cost, were significantly higher for open surgery than for gamma knife, P<0.01. Finally, the total cost (9,812 ±6,981 USD) is higher for open surgery than for gamma knife (23,338 ±95,253 USD), P<0.01. The cost-effectiveness for gamma knife (15 USD/day) is better than for open surgery (44 USD/day), P<0.01. It is pretty meaningful when the cost-effectiveness of socioeconomic cost for gamma knife (15 USD/day) is lower than the cost of working day (36.5 USD/day of our GDP). Conclusions: Most of the costs loss with open surgery for benign skull base tumors comes from the indirect costs of workless days and mortality loss. Gamma knife radiosurgery is still a worthwhile treatment to our patients and to our society because it may shorten hospital stays and workless days and reduce complications, mortality, socio-economic loss, and achieve better cost-effectiveness.

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Xie, Liyue. "Facial artery musculomucosal flap for reconstruction of skull base defects." Thèse, 2013. http://hdl.handle.net/1866/10620.

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Facial Artery Musculomucosal Flap in Skull Base Reconstruction Xie L. MD, Lavigne F. MD, Rahal A. MD, Moubayed SP MD, Ayad T. MD Introduction: Failure in skull base defects reconstruction can have serious consequences such as meningitis and pneumocephalus. The nasoseptal flap is usually the first choice but alternatives are necessary when this flap is not available. The facial artery musculomucosal (FAMM) flap has proven to be successful in head and neck reconstruction but it has never been reported in skull base reconstruction. Objective: To show that the FAMM flap can reach some key areas of the skull base and be considered as a new alternative in skull base defects reconstruction. Methods: We conducted a cadaveric study with harvest of modified FAMM flaps, endoscopic skull base dissection and maxillectomies in 13 specimens. Measures were taken for each harvested FAMM flap. Results: The approximate mean area for reconstruction from the combination of the distal FAMM and the extension flaps is 15.90 cm2. The flaps successfully covered the simulated defects of the frontal sinus, the ethmoid areas, the planum sphenoidale, and the sella turcica. Conclusion: The FAMM flap can be considered as a new alternative in the reconstruction of skull base defects. Modifications add extra length to the traditional FAMM flap and can contribute to a tighter seal of the defect as opposed to the FAMM flap alone.
Le lambeau musculomuqueux de la joue dans la reconstruction de la base du crâne Xie L. MD, Lavigne F. MD, Rahal A. MD, Moubayed SP MD, Ayad T. MD Introduction: Un échec dans la reconstruction de la base du crâne peut avoir des conséquences graves telles que la méningite ou la pneumocéphalie. Le premier choix de la reconstruction est le lambeau nasoseptal. Lorsque ce dernier n’est pas disponible, d’autres alternatives sont nécessaires. Le lambeau musculomuqueux de la joue (FAMM) a une place établie dans la reconstruction des déficits de la tête et du cou, mais il n’a pas jamais été décrit dans la reconstruction de la base du crâne. Objectif: Démontrer que le lambeau de FAMM peut atteindre des zones clés de la base du crâne et être considéré comme une nouvelle option de reconstruction de cette région. Méthode: Nous avons entrepris une étude cadavérique avec prélèvement de lambeaux de FAMM modifiés et une dissection endoscopique de la base du crâne sur 13 spécimens. Des mesures ont été prises pour chaque lambeau prélevé. Résultats: L’aire de reconstruction moyenne du lambeau de FAMM et des extensions est de 15.90 cm2. Les lambeaux couvrent totalement les déficits simulés du sinus frontal, des ethmoïdes, le toit du sphénoïde et la selle turcique. Conclusion: Le lambeau de FAMM peut être considéré comme une nouvelle alternative dans la reconstruction des déficits de la base du crâne. Les modifications apportent une longueur additionnelle et contribuent à une couverture plus étanche du déficit que le lambeau de FAMM seul.

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Tittmann, Mary. "Cochlea-Implantat-Chirurgie: Eine prospektive Studie zur Evaluation eines dreidimensionalen, präoperativen Bildverarbeitungsprogrammes („CI-Wizard“)." 2017. https://ul.qucosa.de/id/qucosa%3A31434.

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Background and Aim: „CI-Wizard“ is a new, three-dimensional software planning tool for cochlear implant surgery with manual and semi-automatic algorithms to visualize anatomical risk structures of the lateral skull base preoperatively. Primary endpoints of the study represented the evaluation of the CI Wizards usability, accuracy, subjectively perceived and objectively measured time in clinical practice. Materials and Methods: In a period from January 2014 to March 2015, n=36 participants were included in this study. These members were divided into three groups of equal number (n=12), but different level of experience. Senior doctors and consultants (group 1), residents (group 2) and medical students (group 3) segmented twelve different CT-scan data sets of the CI Wizard (four per participant). In total, n=144 data sets were collected. The usability of the CI Wizard was measured by the given questionnaire with an interval rating scale. The Jaccard coefficient (JT) was used to evaluate the accuracy of the anatomical structures segmented. The subjectively-perceived time was measured with an interval rating scale in the questionnaire and was compared with the objectively mean measured time (time interact). Results: Across all three groups, the usability of the CI Wizard has been assessed between 1 ('very good') and 2 ('with small defects'). Subjectively, the time was stated as 'appropriate' by questionnaire. Objective measurements of the required duration revealed averages of n=9.8 minutes for creating a target view. Concerning the accuracy, semi automatic anatomical structures such as the external acoustic canal (JT=0.90), the tympanic cavity (JT=0.87), the ossicles (JT=0.63), the cochlea (JT=0.66) and the semicircular canals (JT=0.61) reached high Jaccard values, which describes a great match of the segmented structures between the partcipants and the gold standard. Facial nerve (JT=0.39) and round window (JT=0.37) reached lower Jaccard values. Very little overlap tendency was found for the chorda tympani (JT=0.11). Conclusion: This software program represents a further important step in the development of pre-operative planning tools in cochlear implant surgery. The study revealed a high level of satisfaction in the usability. The subjectively required time was considered as „appropriate“ and the objectively mean measured time was n=9.8 minutes short enough, so that a clinical application seems realistic. Particularly for semi-automatically segmented structures, it represented a good accuracy. For purely manual segmented structures, further improvements are desirable. Finally, this program also provides a good learning tool for medical students and residents to become familiar with the anatomy of the lateral skull base.:1 Einführung 1 1.1 Cochlea Implantate (CI) 1 1.2 Bildverarbeitungsprogamme zur präoperativen Planung eines Cochlea Implantates 2 1.2.1 Segmentierung in der Medizin 2 1.2.2 CI-Wizard 4 1.3 Fragebogen 6 1.4 Zielsetzung 6 1.5 Zusammenfassung der Ergebnisse 7 2 Publikation 8 3 Zusammenfassung 19 4 Literaturverzeichnis 23 Anlagen 26 Beitrag der Promovendin bei geteilter Erstautorenschaft 34 Erklärung über die eigenständige Abfassung der Arbeit 35 Lebenslauf 36 Danksagung 37

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Almeida, Gonçalo Maria Morão Neto de. "Contribuição da Unidade Funcional de Otoneurocirurgia e Neurorrinologia do Hospital de Egas Moniz para o tratamento da patologia da base do crânio." Doctoral thesis, 2017. http://hdl.handle.net/10362/27851.

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RESUMO: A multidisciplinaridade das equipas cirúrgicas de Neurocirurgia e de Otorrinolaringologia, envolvidas no tratamento da patologia da base do crânio, tem-se revelado fundamental para a progressão dos conhecimentos científicos e para a melhoria da qualidade de vida (QOL) dos doentes em todas as suas vertentes. A subespecialização nesta área é, atualmente, uma realidade em inúmeros centros cirúrgicos, nos quais a formação pós-graduada constitui um aspeto fundamental. A equipa de Otoneurocirurgia do Hospital de Egas Moniz, em Lisboa, tem contribuído, desde o final da década de oitenta, para o tratamento de toda a patologia da base do crânio, com um particular relevo para as patologias compartilhadas pelas duas especialidades. A lesão do nervo facial na cirurgia do ângulo ponto-cerebeloso (APC) tem sido difícil de ultrapassar nas últimas décadas. Com o trabalho publicado em 2006 pelo Professor Toshiaki Taoka sobre a utilidade da Tratografia do Nervo Facial (Diffusion Tensor Tractography) na identificação do trajeto do nervo facial, na cisterna do ângulo ponto-cerebeloso, e sua respetiva aplicação na cirurgia dos tumores desta área anatómica, era necessário iniciar uma série de estudos que permitissem determinar o seu eventual contributo na cirurgia dos tumores do APC. A programação deste estudo teve início em 2009, em Roterdão, na Holanda, contando com o envolvimento de uma vasta equipa constituída por Neurocirurgiões, Otorrinolaringologistas, Radiologistas e Neurorradiologistas. Englobou ainda três hospitais: o Hospital de Egas Moniz (HEM), o Hospital Lusíadas Lisboa (HLL), ambos em Lisboa, e o Nara Medical University Hospital (NMUH), no Japão. Até 2011, a equipa desenvolveu vários protocolos de estudo no sentido de melhorar a técnica de imagem para os tumores benignos localizados no ângulo ponto-cerebeloso. Foi iniciado um estudo com um desenho quase-experimental, que decorreu de fevereiro de 2011 a maio de 2015, e durante o qual se desenvolveu e aperfeiçoou uma técnica de imagem inédita em Portugal, com recurso à Ressonância Magnética, a Tratografia do Nervo Facial (Diffusion Tensor Tractography), aplicada à cirurgia dos tumores benignos do ângulo ponto-cerebeloso. Com a finalidade de aferir o contributo de uma equipa de Otoneurocirurgia no tratamento da patologia da base do crânio, propusemos avaliar o impacto da Tratografia do Nervo Facial na cirurgia dos tumores do ângulo ponto-cerebeloso através de três objetivos específicos. O primeiro consistia em medir a influência da Tratografia pré-operatória do nervo facial na morbilidade cirúrgica, com especial ênfase nos Schwannomas Vestibulares. O segundo objetivo era o de classificar o impacto da Tratografia sobre o tempo cirúrgico. Já o terceiro propósito do estudo envolvia a ponderação do efeito da Tratografia nos custos das cirurgias realizadas, com recurso a esta técnica. Foram utilizados dois grupos de pacientes: um grupo de controlo, constituído por 42 participantes submetidos a uma cirurgia aos Schwannomas Vestibulares localizados no ângulo ponto-cerebeloso sem recurso a Tratografia do Nervo Facial, e um grupo experimental, constituído por 25 participantes submetidos a uma cirurgia de tumores benignos no ângulo ponto-cerebeloso com recurso a Tratografia do Nervo Facial. Os resultados demonstraram que a utilização da Tratografia do Nervo Facial no pré-operatório teve repercussões muito relevantes na morbilidade do nervo facial, no tempo cirúrgico e nos custos associados à cirurgia, com maior efetividade no grupo experimental. Verificou-se ainda que a Tratografia do Nervo Facial, como técnica de imagem não invasiva, pode ter um papel muito relevante no futuro, e pode ser alargada a outras regiões anatómicas, como a medula espinal. A evolução dos equipamentos e dos programas informáticos aplicados à imagem, como no presente estudo, será relevante ao fornecer uma informação mais completa sobre os casos cirúrgicos.
ABSTRACT: The multidisciplinarity of the surgical teams of Neurosurgery and Otorhinolaryngology involved in the treatment of the cranial base pathology has been fundamental for the progression of the scientific knowledge as well as for the improvement of the patients’ quality of life (QOL) in all its aspects. Subspecialization in this area is, currently, a reality in many surgical centers, where postgraduate training is a fundamental aspect. The Oto-neurosurgical team at the Egas Moniz Hospital, in Lisbon, has contributed, since the end of the eighties, to the treatment of the skull base pathology, with particular emphasis on the pathologies shared by these two specialties. Facial nerve injury in the surgery of the cerebellopontine angle (APC) has been difficult to overcome in the last decades. With the work published in 2006 by the Professor Toshiaki Taoka, Radiologist at Nara Medical University Hospital, about the usefulness of Facial Nerve Tractography in the identification of the facial nerve pathway, in the cistern of the cerebellopontine angle, and its application in the surgery of tumors in this anatomical area, came the need to initiate a series of studies that should investigate its possible contribution in the reduction of the surgical morbidity. The programming of this study began in Rotterdam, in the Netherlands, in 2009, with a large team of Neurosurgeons, Otorhinolaryngologists, Radiologists and Neuroradiologists. It also had the participation of three hospitals: the Egas Moniz Hospital (HEM), the Lusíadas Lisboa Hospital (HLL), both in Lisbon, and the Nara Medical University Hospital (NMUH), in Japan. Until 2011, the team developed several study protocols to improve the Diffusion Tensor Tractography for benign tumors located at the cerebellopontine angle. The present study, using a quasi-experimental design, ran from February of 2011 to May of 2015, in which a new image technique in Portugal was developed and refined, with the application of the Diffusion Tensor Tractography in the surgery of benign tumors at the cerebellopontine angle. While aiming to evaluate the contribution of an Oto-Neurosurgical team in the treatment of cranial base pathology, we also proposed to assess the impact of the Facial Nerve Tractography in the surgery of tumors at the cerebellopontine angle with three specific objectives. The first one was to measure the influence of a preoperative Facial Nerve Tractography on the surgical morbidity, with special emphasis on the Schwannomas of the vestibular nerve. The second objective was to classify the impact of Tractography on the surgical time, while the third one expected to weight the effect of this technique in the costs of the surgeries performed. Two groups of patients were used: a control group, consisting of 42 participants who were submitted to the surgery of the Vestibular Schwannomas located at the cerebellopontine angle without the use of Facial Nerve Tractography, and an experimental group of 25 participants submitted to surgery of cerebellopontine angle benign tumors with Facial Nerve Tractography. The results showed that the use of Facial Nerve Tractography performed in the preoperative period had relevant repercussions on facial nerve morbidity, surgical time and costs, with greater effectiveness in the experimental group. It was also shown that Facial Nerve Tractography, as a noninvasive imaging technique, may play a very important role in the future and also be extended to other anatomical regions, such as the spinal cord. The evolution of the equipment and of the software applied to the image, as in the present study, will be relevant by giving a more complete information about the surgical cases.

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Books on the topic "Skull Base Neoplasms – surgery"

1

M, Ammirati, and Walter G. F, eds. Surgery of skull base meningiomas. Berlin: Springer-Verlag, 1992.

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Moore, Charles E. Skull base surgery: Basic techniques. San Diego: Plural Pub., 2010.

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Moore, Charles E. Skull base surgery: Basic techniques. San Diego, CA: Plural Pub., 2010.

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Babu, Seilesh. Practical neurotology and skull base surgery. San Diego: Plural Pub., 2013.

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Friedman, Rick A. Lateral skull base surgery: The House Clinic atlas. Edited by House Clinic. New York: Thieme, 2012.

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Sinard, Robert J. Anterior cranial base surgery. Alexandria, VA: American Academy of Otolaryngology--Head and Neck Surgery Foundation, 2005.

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Draf, Wolfgang, Ricardo L. Carrau, Amin B. Kassam, Peter Vajkoczy, and Ulrike Bockmühl. Endonasal endoscopic surgery of skull base tumors: An interdisciplinary approach. Stuttgart: Thieme, 2015.

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European Skull Base Society. Congress. Skull base surgery.: Proceedings of the First Congress of the European Skull Base Society, Riva del Garda, Italy, September 25-30, 1993. Amsterdam: Kugler Publications, 1995.

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International Conference on Acoustic Neuroma Surgery (2nd 1995 Paris, France). Acoustic neuroma and skull base surgery: Proceedings of the 2nd International Conference on Acoustic Neuroma Surgery and 2nd European Skull Base Society Congress, Paris, France, April 22-26, 1995. Amsterdam: Kugler Publications, 1996.

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Al-Mefty, Ossama. Operative atlas of meningiomas. Philadelphia: Lippincott-Raven, 1998.

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Book chapters on the topic "Skull Base Neoplasms – surgery"

1

Alt, Jeremiah A., Demetri Arnaoutakis, and Iman Naseri. "Skull Base Neoplasms." In Encyclopedia of Otolaryngology, Head and Neck Surgery, 2483–500. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-23499-6_92.

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York, Christopher, Joe Walter Kutz, Brandon Isaacson, and Peter Sargent Roland. "Osteoradionecrosis of Skull Base (Benign Neoplasia-Paragangliomas)." In Encyclopedia of Otolaryngology, Head and Neck Surgery, 1967–71. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-23499-6_706.

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Oghalai, John S., and Colin L. W. Driscoll. "Temporal Bone Surgery for Encephaloceles, Superior Semicircular Canal Dehiscence, Neoplasia, and Lesions of the Petrous Apex." In Atlas of Neurotologic and Lateral Skull Base Surgery, 221–62. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-46694-0_8.

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Roosen, N., T. Kahn, J. C. W. Kiwit, G. Fürst, and E. Lins. "Magnetic Resonance in Modern Neuroimaging of Skull Base Neoplasms with Particular Reference to the Evaluation of Complications of Medically and Surgically Treated Pituitary Adenomas." In Surgery of the Sellar Region and Paranasal Sinuses, 205–10. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-76450-9_36.

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Traul, David E., and Thomas N. Pajewski. "Skull Base Surgery." In Monitoring the Nervous System for Anesthesiologists and Other Health Care Professionals, 425–34. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-46542-5_27.

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Pajewski, Thomas N., and David E. Traul. "Skull Base Surgery." In Monitoring the Nervous System for Anesthesiologists and Other Health Care Professionals, 473–86. Boston, MA: Springer US, 2011. http://dx.doi.org/10.1007/978-1-4614-0308-1_24.

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Dubey, Siba P., Charles P. Molumi, and Herwig Swoboda. "Skull Base Surgery." In Color Atlas of Head and Neck Surgery, 485–537. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-29809-8_15.

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Farhadieh, Ross D., and Wayne A. J. Morrison. "Skull base reconstruction." In Plastic and reconstructive surgery, 362–65. Chichester, UK: John Wiley & Sons, Ltd, 2015. http://dx.doi.org/10.1002/9781118655412.ch29.

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Snyderman, Carl H., Paul A. Gardner, Juan C. Fernandez-Miranda, Elizabeth C. Tyler-Kabara, and Eric W. Wang. "Endoscopic Skull Base Surgery." In Craniomaxillofacial Reconstructive and Corrective Bone Surgery, 461–75. New York, NY: Springer New York, 2019. http://dx.doi.org/10.1007/978-1-4939-1529-3_36.

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Gil, Ziv, Avraham Abergel, and Nevo Margalit. "Endoscopic Skull Base Surgery." In Tumours of the Skull Base and Paranasal Sinuses, 105–30. New Delhi: Springer India, 2012. http://dx.doi.org/10.1007/978-81-322-2583-6_7.

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Conference papers on the topic "Skull Base Neoplasms – surgery"

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Matinfar, M., C. Baird, A. Batouli, R. Clatterbuck, and P. Kazanzides. "Robot-assisted skull base surgery." In 2007 IEEE/RSJ International Conference on Intelligent Robots and Systems. IEEE, 2007. http://dx.doi.org/10.1109/iros.2007.4399012.

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Kwon, Seongil, Wooseok Choi, Geunwoong Ryu, Sungchul Kang, and Keri Kim. "Endoscopic Endonasal Skull Base Surgery system." In 2017 14th International Conference on Ubiquitous Robots and Ambient Intelligence (URAI). IEEE, 2017. http://dx.doi.org/10.1109/urai.2017.7992665.

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Kothare, Pratima. "Endoscopic skull base surgery-anaesthesia considerations." In 17th Annual Conference of Indian Society of Neuroanaesthesiology and Critical Care. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0038-1667599.

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Przepiorka, Lukasz, Przemyslaw Kunert, Tomasz Dziedzic, Wiktoria Rutkowska, and Andrzej Marchel. "Surgery after Surgery for Vestibular Schwannoma." In 30th Annual Meeting North American Skull Base Society. Georg Thieme Verlag KG, 2020. http://dx.doi.org/10.1055/s-0040-1702502.

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Glicksman, Jeffrey, Maria Peris-Celda, Tyler Kenning, Edward Wladis, and Carlos Pinheiro-Neto. "Endoscopic Endonasal Orbital Surgery." In 30th Annual Meeting North American Skull Base Society. Georg Thieme Verlag KG, 2020. http://dx.doi.org/10.1055/s-0040-1702447.

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Tamiya, Takashi, Masahiko Kawanishi, and Shuxiang Guo. "Skull base surgery using Navigation Microscope Integration system." In 2011 IEEE/ICME International Conference on Complex Medical Engineering - CME 2011. IEEE, 2011. http://dx.doi.org/10.1109/iccme.2011.5876729.

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Lazak, J., J. Plzak, and Z. Fik. "Skull base reconstruction after the vestibular schwannoma surgery." In Abstract- und Posterband – 91. Jahresversammlung der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn – Welche Qualität macht den Unterschied. © Georg Thieme Verlag KG, 2020. http://dx.doi.org/10.1055/s-0040-1711308.

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Kwon, Seong-il, Geunwoong Ryu, Sungchul Kang, and Keri Kim. "A Steerable Endoscope for Transnasal Skull Base Surgery." In 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2018. http://dx.doi.org/10.1109/embc.2018.8513308.

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Shah, Ravi, Ivy Maina, Neil Patel, Vasiliki Triantafillou, Alan Workman, Edward Kuan, Charles Tong, et al. "Incidence, Risk Factors, and Outcomes of Endoscopic Sinus Surgery after Endoscopic Skull Base Surgery." In 29th Annual Meeting North American Skull Base Society. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1679733.

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Benjamin, Carolina, Donato Pacione, Julia Bevilacqua, David Kurland, Arianne Lewis, John Golfinos, Chandra Sen, et al. "Quality Improvement in Endoscopic Endonasal Surgery." In 29th Annual Meeting North American Skull Base Society. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1679475.

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