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1

Arumningtyas, Restu Maharany, Agung Triono, and Retno Sutomo. "Sleep disturbance associations with blood pressure and body mass index in school-aged children." Paediatrica Indonesiana 60, no. 6 (October 16, 2020): 303–9. http://dx.doi.org/10.14238/pi60.6.2020.303-9.

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Background Sleep disturbances can lead to many health problems in school-aged children, including hypertension and obesity. However, a lack of consensus about the etiology of these conditions is due to conflicting reports on the possible effects of sleep disturbances. Objective To assess for possible associations between sleep disturbances and blood pressure as well as body mass index in school-aged children. Methods This cross-sectional study involved primary school children in the 4th-5th grades. Subjects’ blood pressure, body weight, and body height were measured and their parents completed the Sleep Disturbances Scale for Children (SDSC) questionnaire. Results Of the 816 children enrolled, 503 (61.6%) children had sleep disturbances. The most common type of sleep disturbance was initiating and maintaining sleep. Bivariate analysis revealed a significantly increased risk of hypertension among subjects with sleep disturbances (PR 15.06; 95%CI 8.13 to 27.90) and increased risk of obesity (PR 22.65; 95%CI 12.28 to 41.78). Conclusion The most common type of sleep disturbance is initiating and maintaining sleep. Sleep disturbances are significantly associated with hypertension and obesity in children.
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Dennis, Jeff A., Ahmad Alazzeh, Ann Marie Kumfer, Rebecca McDonald-Thomas, and Alan N. Peiris. "The Association of Unreported Sleep Disturbances and Systemic Inflammation: Findings from the 2005-2008 NHANES." Sleep Disorders 2018 (October 9, 2018): 1–8. http://dx.doi.org/10.1155/2018/5987064.

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Background/Objective. Sleep apnea is associated with elevated inflammatory markers. A subgroup of patients never report sleep disturbances to their physician. The inflammatory status of this subgroup is not known. The present study aims to evaluate two inflammatory markers, C-reactive protein (CRP) and red cell distribution width (RDW), in those with unreported sleep disturbances and compares these findings to those with and without reported sleep disorders. We also investigate the utility of RDW as an inflammatory marker in sleep disorders. Methods. Sample includes 9,901 noninstitutionalized, civilian, nonpregnant adults from the 2005-2008 National Health and Nutrition Examination Survey, a nationally representative, cross-sectional U.S. study. Sleep questionnaire and laboratory data were used to compare inflammatory markers (CRP and RDW) in five subgroups of individuals: reporting physician-diagnosed sleep apnea, reporting another physician-diagnosed sleep disorder, reported sleep disturbance to physician with no resulting diagnosis, unreported sleep disturbance (poor sleep quality not reported to physician), and no diagnosed sleep disorder or sleep disturbance. Results. Individuals with unreported sleep disturbance had significantly higher odds of elevated RDW (>13.6%) when compared to those without a sleep disturbance in adjusted models (OR=1.33). Those with unreported sleep disturbance had significantly higher odds of elevated CRP levels (>1 mg/L) than those without sleep disturbances (OR 1.34), although the association was not significant when adjusted for obesity and other controls. Conclusion. Self-identified unreported sleep disturbances are associated with significantly higher odds of elevated RDW than those without sleep disturbances. RDW may serve as a valuable indicator in identifying individuals at higher risk for sleep apnea and other sleep disorders.
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Liu, Shou, Ines H. I. Chow, Li Lu, Yan-Ming Ren, Hui-Lian Yang, Sheng-Yan Jian, Chee H. Ng, Gabor S. Ungvari, Fei Wang, and Yu-Tao Xiang. "Comparison of Sleep Disturbances Between Older Nursing Home Residents in High- and Low-Altitude Areas." Journal of Geriatric Psychiatry and Neurology 33, no. 6 (December 16, 2019): 370–76. http://dx.doi.org/10.1177/0891988719892335.

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Background and Objective: This study compared sleep disturbances between older adults living in nursing home located in high- and low-altitude areas and explored the association between sleep disturbances and quality of life (QoL). Method: In total, 207 participants living in a high-altitude area and 437 participants in a low-altitude area were included. Sleep disturbances (ie, difficulty in initiating sleep, difficulty in maintaining sleep, and early morning awakening) were measured using standardized questions. The independent demographic and clinical correlates of sleep disturbances in high-altitude area were examined using multiple logistic regression analyses. Each type of sleep disturbance was entered as the dependent variable separately, while those with significant group differences in the univariate analyses (ie, male gender, married status, age and depressive symptoms) were entered as independent variables. Results: The prevalence of any type of sleep disturbances in the whole sample was 26.09%, with 41.54% in the high-altitude area and 18.76% in the low-altitude area. Physical, psychological, social, and environmental QoL domains were negatively associated with sleep disturbances in high-altitude area. Multiple logistic regression analyses revealed that male gender and married status were less likely to have sleep disturbances, while those with more severe depressive symptoms were more likely to have sleep disturbances in high-altitude area. Conclusion: Sleep disturbance is common among older nursing home residents in high-altitude areas. Considering the negative impact of sleep disturbance on QoL, regular screening and treatment strategies need to be developed directly for this population.
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Webster, Lucy, Kingsley Powell, Sergi G. Costafreda, and Gill Livingston. "The impact of sleep disturbances on care home residents with dementia: the SIESTA qualitative study." International Psychogeriatrics 32, no. 7 (May 21, 2020): 839–47. http://dx.doi.org/10.1017/s1041610220000642.

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ABSTRACTObjectives:Nearly 40% of care home residents who are living with dementia also have symptoms of disturbed sleep. However, the impact of these disturbances is relatively unknown and is needed to indicate whether interventions are warranted; therefore, we aimed to investigate the impact.Design:One-to-one semi-structured interviews.Settings:Four UK care homes.Participants:We interviewed 18 nurses and care assistants about residents with sleep disturbances.Measurements:We used a topic guide to explore staff experience of sleep disturbance in residents with dementia. The interviews were audio recorded and transcribed and then analyzed thematically by two researchers independently.Results:Staff described that sleep disturbances in most, but not all, residents impacted negatively on the resident, other residents, staff, and relatives. Residents became more irritable or agitated if they had slept badly. They slept in the daytime after a bad night, which then increased their chances of being awake the following night. For some, being sleepy in the day led to falls, missing medication, drinks, and meals. Staff perceived hypnotics as having low efficacy, but increasing the risk of falls and drowsiness. Other residents were disturbed by noise, and staff described stress when several residents had sleep disturbance. Some of the strategies reported by staff to deal with sleep disturbances such as feeding or providing caffeinated tea at night might be counterproductive.Conclusions:Sleep disturbances in care home residents living with dementia negatively affect their physical and psychological well-being. These disturbances also disturb other residents and increase stress in staff.
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Amiri, Alireza, Minoo Kalantari, and Farzad Gharebashloo. "Association between leisure activities and sleep disturbances among children with and without cerebral palsy." International Journal of Therapy and Rehabilitation 29, no. 9 (September 2, 2022): 1–16. http://dx.doi.org/10.12968/ijtr.2021.0015.

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Background/Aims Sleep disturbances are common among children with cerebral palsy, resulting in adverse consequences. Investigating the association between leisure activities and sleep disturbances could help to develop ways to promote their sleep quality. This study primarily aimed to investigate the association between leisure activities and sleep disturbances among children with and without cerebral palsy. The secondary aim was to study the prevalence of sleep disturbances and some of its associated factors. Methods A total of 75 children with cerebral palsy (study group) (mean age 10.0 ± 2.5 years) and 75 typically developing children (control group) (mean age 10.5 ± 2.9 years) were randomly selected to completed the Children's Assessment of Participation and Enjoyment. Sleep disturbances were assessed using the Sleep Disturbance Scale for Children. Factors associated with sleep disturbances (age, gender, school attendance, bedroom sharing, type of cerebral palsy, motor functions, eating and drinking ability and communication functions) were statistically analysed and the prevalence of sleep disturbances was calculated. Results Overall frequency of leisure participation was strongly correlated with overall sleep disturbances (P<0.001) among both groups. The prevalence of overall sleep disturbances was 17.1% and 10.6% among the study and the control groups respectively. Eating and drinking ability and spastic quadriplegia emerged as the strongest predictors of overall negative scores on the Sleep Disturbance Scale for Children. Conclusions Greater participation in leisure activities is associated with better sleep. Occupational therapists are encouraged to consider this association when planning for occupation-based interventions aimed at enhancing occupational performance.
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Merin, Neenu, and Regina Antony. "SLEEP DISTURBANCE AND QUALITY OF SLEEP AMONG PATIENTS WITH CARDIOVASCULAR DISEASES." Asian Journal of Pharmaceutical and Clinical Research 12, no. 1 (January 7, 2019): 263. http://dx.doi.org/10.22159/ajpcr.2018.v12i1.28622.

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Objective: This was a descriptive study with the objective to determine the sleep disturbances and the quality of sleep among patients with cardiovascular diseases (CVDs).Methods: Quantitative approach with non-experimental descriptive design was used. A semi-structured sleep disturbance questionnaire was used to determine the sleep disturbances, and a standardized Pittsburgh Sleep Quality Index tool was used to assess the sleep quality among 100 subjects in Amrita Institute of Medical Sciences, Kochi.Results: The study results showed that majority of the subjects (51%) were of the age group between 56 and 65 years, and 71% were male with CVD. Sleep disturbances were present in 80% of the subjects with CVD, among which 56% subjects had mild disturbances, 20% subjects with moderate sleep disturbances, and 4% subjects with severe sleep disturbances. The result also indicated that 48% of subjects had poor sleep quality. Findings also showed a highly statistically significant association between cardiomyopathy and sleep disturbances (p<0.001). Total cholesterol and low-density cholesterol levels were significantly associated with sleep disturbances (p<0.05). There is a highly significant association between sleep disturbances and quality of sleep (p<0.001), indicating that sleep disturbances can be one factor in decreasing the quality of sleep in patients with CVD.Conclusion: The results of the study indicated that sleep disturbances were prevalent in patients with CVD and often hazardous to heart health. As health practitioner and other health-care providers have not focused major attention on the importance of sleep to health, the need for providing information to them and patients regarding the importance of improving the quality of sleep and identifying the sleep disturbances will call for action to bring sleep to the forefront of public health.
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Merin, Neenu, and Regina Antony. "SLEEP DISTURBANCE AND QUALITY OF SLEEP AMONG PATIENTS WITH CARDIOVASCULAR DISEASES." Asian Journal of Pharmaceutical and Clinical Research 12, no. 1 (January 7, 2019): 263. http://dx.doi.org/10.22159/ajpcr.2019.v12i1.28622.

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Objective: This was a descriptive study with the objective to determine the sleep disturbances and the quality of sleep among patients with cardiovascular diseases (CVDs).Methods: Quantitative approach with non-experimental descriptive design was used. A semi-structured sleep disturbance questionnaire was used to determine the sleep disturbances, and a standardized Pittsburgh Sleep Quality Index tool was used to assess the sleep quality among 100 subjects in Amrita Institute of Medical Sciences, Kochi.Results: The study results showed that majority of the subjects (51%) were of the age group between 56 and 65 years, and 71% were male with CVD. Sleep disturbances were present in 80% of the subjects with CVD, among which 56% subjects had mild disturbances, 20% subjects with moderate sleep disturbances, and 4% subjects with severe sleep disturbances. The result also indicated that 48% of subjects had poor sleep quality. Findings also showed a highly statistically significant association between cardiomyopathy and sleep disturbances (p<0.001). Total cholesterol and low-density cholesterol levels were significantly associated with sleep disturbances (p<0.05). There is a highly significant association between sleep disturbances and quality of sleep (p<0.001), indicating that sleep disturbances can be one factor in decreasing the quality of sleep in patients with CVD.Conclusion: The results of the study indicated that sleep disturbances were prevalent in patients with CVD and often hazardous to heart health. As health practitioner and other health-care providers have not focused major attention on the importance of sleep to health, the need for providing information to them and patients regarding the importance of improving the quality of sleep and identifying the sleep disturbances will call for action to bring sleep to the forefront of public health.
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Kashani, A. A. "Sleep Disturbances." Ophthalmology 112, no. 10 (October 2005): 1847–48. http://dx.doi.org/10.1016/j.ophtha.2005.03.020.

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Redline, Susan, and JoAnne Foody. "Sleep Disturbances." Circulation 124, no. 19 (November 8, 2011): 2049–51. http://dx.doi.org/10.1161/circulationaha.111.062190.

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Phattanarudee, Siripan, Sunisa Sangthong, and Roongroj Bhidayasiri. "Association between Sleep Disturbances and Daytime Somnolence in Parkinson’s Disease." European Neurology 80, no. 5-6 (2018): 268–76. http://dx.doi.org/10.1159/000496937.

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Background: Sleep disturbance is a common problem among patients with Parkinson’s disease (PD). Objectives: To investigate the prevalence of daytime somnolence and night-time sleep disturbances; to characterise the night-time sleep disturbance in patients with daytime somnolence; and to determine the correlation between daytime somnolence and night-time sleep disturbances. Methods: One hundred and sixty patients with PD were included in the study. Each patient completed the Thai version of the Epworth Sleepiness Scale (ESS) questionnaire to evaluate excessive daytime sleepiness (EDS), and the PD Sleep Scale version-2 (PDSS-2) questionnaire to evaluate night-time sleep disturbance. Subjective sleep information and details about the presence or absence of sleep attack (SA) were also obtained from the patients. Results: The types of daytime somnolence found in this study were EDS, SA, and combination of EDS and SA (EDS + SA) with the prevalence rates of 22.5, 3.1 and 6.3%, respectively. The prevalence of night-time sleep disturbance was 46.9%. The most common nocturnal disturbance (82.5%) was “get up at night to pass urine”. There was a significant positive correlation between the ESS score and PDSS-2 total score with a correlation coefficient of 0.16 (p = 0.043). Patients with “EDS + SA” were the most affected by nocturnal disturbances, as they represented the largest group among those patients with night-time disturbances and had the highest PDSS-2 total score (p < 0.05). Conclusion: There are differences in nocturnal sleep disturbances among PD patients with different types of daytime somnolence. The significant positive correlation between the ESS and the PDSS-2 total scores suggests that night-time sleep disturbance may influence daytime somnolence.
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Puzino, Kristina, Amanda Pearl, Susan Calhoun, Jamal Essayli, Danielle Alexander, Michael Murray, and Julio Fernandez-Mendoza. "692 Longitudinal Stability of Sleep and Health Correlates in Adults with Autism Spectrum Disorder." Sleep 44, Supplement_2 (May 1, 2021): A270—A271. http://dx.doi.org/10.1093/sleep/zsab072.690.

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Abstract Introduction Individuals with Autism Spectrum Disorder (ASD) experience sleep disturbances to a greater degree than the general population. The majority of research investigating sleep disturbances in ASD has focused on children and adolescents. The aim of the current study was to determine the stability and health correlates of self-reported sleep disturbances in adults with ASD. Methods Participants included 55 adults with ASD recruited from state-funded Pennsylvania programs (31.2±7.6 years old, 80% male, 10.9% minority). Patient-Reported Outcomes Measurement Information System (PROMIS) measures assessing Sleep Disturbances, Sleep-Related Impairment, Fatigue, Anxiety, Depression, Anger, and Physical Health, were completed at baseline and every 90 ± 14 days over a 2-year period. Intraclass correlation coefficients (ICC) were calculated for each sleep outcome, and interpreted as 0.00–0.20=“poor stability,” 0.21–0.40=“slight stability,” 0.41–0.60=“moderate stability,” 0.61–0.80=“substantial stability,” and 0.81–1.00=“almost perfect stability” across the first three time-points. Linear mixed models examined the independent association of sleep disturbances, sleep-related impairment, and fatigue on anxiety, depression, anger, and physical health over the two-year period. Results Sleep-related impairment (ICC=0.73) and fatigue (ICC=0.64) were substantially stable, while sleep disturbances were moderately stable (ICC=0.58). All three sleep-related outcomes were independently associated with anxiety (sleep-related impairment p=0.012; sleep disturbance p&lt;0.001; fatigue p=&lt;0.001) and anger (sleep-related impairment p=&lt;0.001; sleep disturbance p=0.001; fatigue p&lt;0.001) across the two-year period. Sleep disturbance (p=&lt;0.001) and fatigue (p&lt;0.001), but not sleep-related impairment (p=0.267), were associated with depression across the two-year period. In contrast, none of the sleep-related outcomes (sleep-related impairment p=0.285; sleep disturbance p=0.250; fatigue p=0.709) were associated with physical health over time. Conclusion Measures of sleep-related impairment, fatigue, and sleep disturbance remained stable over time, suggesting that they can provide clinicians and researchers with a brief, accurate, and reliable way to assess patient-reported sleep outcomes in adults with ASD. Furthermore, given the stability of these sleep measures and their independent association with elevated mental health outcomes, there is a need for evidence-based treatments targeting sleep difficulties and associated symptomology in adults with ASD, a particularly underserved population. Support (if any) Pennsylvania State Bureau of Autism Services through the Autism Services, Education, Resources, and Training (ASERT) grant
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Armendariz, Jessica R., S. Duke Han, and Constance H. Fung. "A Scoping Review and Conceptual Framework Examining the Role of Sleep Disturbance in Financial Exploitation in Older Adults." Gerontology and Geriatric Medicine 8 (April 2022): 233372142211162. http://dx.doi.org/10.1177/23337214221116233.

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Sleep disturbances and financial exploitation have both been linked to impaired cognitive ability, loneliness, and depressed mood in older adults, suggesting a potential role of sleep disturbances in increasing vulnerability to financial exploitation. We sought to identify evidence linking sleep disturbances to financial exploitation. We conducted a systematic search of MEDLINE, PubMed Central, and National Center for Biotechnology Information Bookshelf for relevant published articles on sleep and financial exploitation. Three studies examining both sleep and financial exploitation were identified. None of the studies explored sleep disturbances as a cause of financial exploitation. More work needs to be done to examine the role of sleep disturbances in financial exploitation. We propose a conceptual framework for identifying possible associations among sleep disturbance, biopsychosocial, and decision-related situational factors to guide further exploration of relationships between sleep and financial exploitation.
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Yun, Sehyun, Minsuk Kim, Won-Tae Lee, Jin-Ha Yoon, and Jong-Uk Won. "Irregular Work Hours and the Risk of Sleep Disturbance Among Korean Service Workers Required to Suppress Emotion." International Journal of Environmental Research and Public Health 18, no. 4 (February 5, 2021): 1517. http://dx.doi.org/10.3390/ijerph18041517.

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Although a necessity in a modern society, irregular work schedule can lead to sleep problems. We investigated the effect of work schedule irregularity on sleep disturbance of 17,846 Korean service workers using the fifth Korean Working Conditions Survey. The odds ratio (OR) and 95% confidence interval (CI) for sleep disturbance occurrence were calculated through a multiple logistic regression model. The adjusted ORs for moderate and severe sleep disturbances for those with irregular work hours were 2.11 (95% CI 1.90–2.33) and 3.10 (95% CI 2.62–3.66), respectively. Work schedule irregularity and emotion suppression at work showed synergistic effect on both moderate and severe sleep disturbances. Sleep disturbances can lead to brain function deterioration and work-related injuries; therefore, appropriate measures should be addressed for the vulnerable population.
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Matthews, Ellyn E. "Sleep Disturbances and Fatigue in Critically Ill Patients." AACN Advanced Critical Care 22, no. 3 (July 1, 2011): 204–24. http://dx.doi.org/10.4037/nci.0b013e31822052cb.

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Sleep disturbances and fatigue are significant problems for critically ill patients. Existing sleep disorders, underlying medical/surgical conditions, environmental factors, stress, medications, and other treatments all contribute to a patient’s inability to sleep. Sleep disturbance and debilitating fatigue that originate during acute illness may continue months after discharge from intensive care units (ICUs). If these issues are unrecognized, lack of treatment may contribute to chronic sleep problems, impaired quality of life, and incomplete rehabilitation. A multidisciplinary approach that incorporates assessment of sleep disturbances and fatigue, environmental controls, appropriate pharmacologic management, and educational and behavioral interventions is necessary to reduce the impact of sleep disturbances and fatigue in ICU patients. Nurses are well positioned to identify issues in their own units that prevent effective patient sleep. This article will discuss the literature related to the occurrence, etiology, and risk factors of sleep disturbance and fatigue and describe assessment and management options in critically ill adults.
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Valladares, Edwin M., and Michael R. Irwin. "Polysomnographic Sleep Dysregulation in Cocaine Dependence." Scientific World JOURNAL 7 (2007): 213–16. http://dx.doi.org/10.1100/tsw.2007.264.

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Insomnia and sleep disturbance are associated with declines in health functioning, alongwith increases in mortality risk. Given the prominence of reported sleep disturbance incocaine-dependent subjects and persistence into recovery, understanding the natureand severity of these disturbances in this population may help to identify relevantpathways that contribute to the increased mortality in cocaine dependence. Polysomnography provides a means of objectively characterizing sleep and, in turn, sleep disturbances. Few studies have used polysomnography to evaluate sleep incocaine-dependent persons, yet these studies have the potential to advance treatmentsthat will ultimately reduce morbidity in cocaine-dependent subjects.
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Pignatiello, Grant. "0258 Systemic Determinants and Consequences of Sleep Disturbance in Family Members of the Critically Ill." Sleep 45, Supplement_1 (May 25, 2022): A116. http://dx.doi.org/10.1093/sleep/zsac079.256.

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Abstract Introduction Family members of intensive care unit (ICU) patients are at increased risk of experiencing sleep disturbances, which in turn can exacerbate symptoms of anxiety and depression. However, little is known about how sociocultural determinants influence their predisposition to sleep disturbances, and how such sleep disturbances contribute to symptoms of anxiety and depression across the trajectory of the patient’s ICU stay. Therefore, we sought to: 1) identify individual and interpersonal sociocultural predictors of sleep disturbance symptoms, and 2) describe the influence of select sociocultural determinants and sleep disturbances on subsequent symptoms of anxiety and depression. Methods Using a repeated-measures, correlational design, we recruited family members of incapacitated, mechanically ventilated patients within four adult intensive care units at a tertiary medical center in northeast Ohio. We collected baseline data (T1) after obtaining informed consent and seven (T2) days post-baseline. We measured individual and interpersonal sociocultural determinants, as well as symptoms of sleep disturbance, anxiety, and depression with self-report instruments. To test our aims, we used step-wise linear regression. Results For aim 1 (N = 30), participants who were female, non-white, married, and had prior healthcare decision-making experience reported more severe sleep disturbance symptoms (R2 = .69, F(11,18) = 3.59, p = .008). For aim 2 (n = 20), the aforementioned determinants and T1 sleep disturbance scores significantly predicted T2 anxiety (R2 = .62, F(5,14) = 4.61, p = .01) and depression (R2 = .65, F(5,14) = 5.24, p = .006) severity. None of the predictors were statistically significant for the full anxiety model; notably, the effects of gender and prior healthcare decision-making experience were statistically significant until T1 sleep disturbance was inserted in the model. T1 sleep disturbance scores were the only statistically significant predictor in the full depression model. Conclusion We provide preliminary evidence that sleep disturbances among family members of ICU patient may contribute to the severity of depressive symptoms in family members of ICU patients. We encourage future researchers to replicate and expand upon these findings to understand the development of sleep disparities in this vulnerable population. Support (If Any) Sayre Memorial Fund; Midwest Nursing Research Society; NCATS (1KL2TR002547)
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N., Rama Swathika, Kalyani P., and John William Felix A. "Sleep disturbances and its associated factors among the college students in Tamil Nadu- a cross sectional study." International Journal Of Community Medicine And Public Health 9, no. 12 (November 28, 2022): 4655. http://dx.doi.org/10.18203/2394-6040.ijcmph20223228.

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Background: The key building block of good health is sleep. According to sleep foundation the term sleep disturbance is defined as a disruption in sleep that causes arousal or awakening. Sleep disturbances is a widespread common health problem among university students who are entering into adulthood. The present study was done with the objective of finding the prevalence of sleep disturbances among the college students studying in university of Tamil Nadu.Methods: This was a cross sectional study done among 536 participants, whose sleep disturbances were assessed using pre-tested, pre-designed questionnaire. Descriptive and Analytical statistics were used. Analytical statistics was done using Chi-square test and binominal logistic regression.Results: Out of 536 students, 299 (55.78%) were suffering from sleep disturbances among which 70.9% were females and 83% of them had less than 1 hour time gap between screen time and their regular sleep. There was a significant association between sleep disturbances and repeated worrying about lots of tests, feeling lost something in life, felt badly about pandemic/online teaching, felt isolated and often taking food out of hostel/home.Conclusions: This study showed that majority of college students suffer from sleep disturbances, as their stress levels goes up and their physical activity goes down.
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Efremov, I. S., A. R. Asadullin, R. F. Nasyrova, E. A. Akhmetova, and E. M. Krupitsky. "Alcohol and sleep disturbances." V.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY, no. 3 (October 11, 2020): 27–34. http://dx.doi.org/10.31363/2313-7053-2020-3-27-34.

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This article presents a non-systematic descriptive review of sleep disturbance problems in patients with alcohol dependence. A search was carried out in databases such as Google Scholar, ELibrary.ru, Scopus, PubMed. We considered works published no earlier than January 1, 2015, but no later than January 10, 2020. A search was carried out with the use of search queries of various combinations of the specified words: “alcohol use disorder,” “alcoholism”, “insomnia,” and others. After analyzing a number of publications, it is possible to conclude that the relationship between the described phenomena is synergetic with a mutual reinforcement. In the current review it is demonstrated that the risk of the development of alcoholism against the background of sleep disturbances might be related to the initial use of alcohol as a somnolent with further development of tolerance and alcoholism. At the same time, the severity of sleep disturbances quite often coincides with the severity of alcohol dependence. For those patients who are in a stage of remission sleep disturbances is a risk factor for relapse. This review clearly demonstrates that further research of the relationships between alcohol dependence and sleep disorders are needed.
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Erickson, Jeanne, and Ann M. Berger. "Sleep-Wake Disturbances." Clinical Journal of Oncology Nursing 15, no. 2 (March 28, 2011): 123–27. http://dx.doi.org/10.1188/11.cjon.123-127.

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Bernardo, M. L. "Disturbances of Sleep." Complementary Health Practice Review 5, no. 1 (March 1, 1999): 83–85. http://dx.doi.org/10.1177/153321019900500112.

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Hillman, David R. "Postoperative Sleep Disturbances." Advances in Anesthesia 35, no. 1 (2017): 1–24. http://dx.doi.org/10.1016/j.aan.2017.07.001.

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Meaklim, H., M. Monfries, I. C. Rehm, M. Junge, L. J. Meltzer, and M. L. Jackson. "1171 Commonly Encountered Yet Not Confident: Graduate Psychology Students’ Experience and Confidence Managing Sleep Disturbances." Sleep 43, Supplement_1 (April 2020): A447. http://dx.doi.org/10.1093/sleep/zsaa056.1165.

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Abstract Introduction Trainee psychologists receive minimal sleep education during graduate psychology training programs, despite the frequent co-occurrence of sleep disturbances in mental health conditions. This study aimed to explore graduate psychology students’ experience working with sleep disturbances and their perceived skills and confidence to assess and treat sleep problems in clinical practice. Methods Australian graduate psychology students (N = 163) completed a novel survey developed specifically for the study, inquiring about their experience, skills and confidence to manage sleep disturbances in clinical practice. Students perceived skills to manage sleep disturbances were recorded on a 7-point Likert scale, where 1 = ‘strongly disagree’ and 7 = ‘strongly agree’. Students’ confidence to treat specific sleep disorders was also recorded. Results Sixty-eight percent of students reported having already worked with a client who experienced a sleep disturbance as part of their training. However, students’ perceived skills to assess and treat sleep disturbances were low. Only 14.9% ‘agreed’ or ‘strongly agreed’ that they had the skills to assess and diagnose common sleep disorders (M = 3.22, SD = 1.75). Similarly, less than a quarter of students ‘agreed’ or ‘strongly agreed’ that they felt comfortable using common sleep-related assessments (23.7%; M = 3.56, SD = 1.96) or empirically-supported interventions for sleep disturbances (22.6%; M = 3.71, SD = 1.83). The majority of students reported they were ‘not confident at all’ to treat parasomnias (80.3%); hypersomnias (77.9%); OSA (71.3%); circadian rhythm disorders (50%) or insomnia (41%). Conclusion Graduate psychology students report low levels of confidence in assessing and managing sleep disturbances in clinical practice, despite over two-thirds of students already working with clients experiencing sleep difficulties. Clinical training in the management of sleep disturbances is required for graduate psychology students. Support N/A
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Seo, Wan Seok. "An update on the cause and treatment of sleep disturbance in children and adolescents with autism spectrum disorder." Yeungnam University Journal of Medicine 38, no. 4 (October 31, 2021): 275–81. http://dx.doi.org/10.12701/yujm.2021.01410.

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Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by abnormalities in social communication/interaction and restrictive, repetitive patterns of behavior. ASD is a relatively common psychiatric disorder, with a prevalence of approximately 1.7% in children. Although many children and adolescents with ASD visit the hospital for medical help for emotional and behavioral problems such as mood instability and self-harming behavior, there are also many visits for sleep disturbances such as insomnia and sleep resistance. Sleep disturbances are likely to increase fatigue and daytime sleepiness, impaired concentration, negatively impact on daytime functioning, and pose challenges in controlling anger and aggressive behavior. Sleep disturbance in children and adolescents with ASD negatively affects the quality of life, nothing to say the quality of life of their families and school members. In this review, sleep disturbances that are common in children and adolescents with ASD and adolescents are presented. The developmental and behavioral impacts of sleep disturbances in ASD were also considered. Finally, non-pharmacological and pharmacological treatments for sleep disturbances in children and adolescents with ASD and adolescents are reviewed.
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Matsuda, Eiko, and Mariko Kikutani. "The Interactive Influence of Life Stressor and Sleep Disturbance on Depression: A Cross-Sectional Examination on Chinese and Japanese University Students." SAGE Open 12, no. 1 (January 2022): 215824402210866. http://dx.doi.org/10.1177/21582440221086610.

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The present study investigated how life stressors and sleep disturbances interactively affect depressive symptoms among university students. Based on a hypothesis that sleep disturbance can be a cause of depression, a statistical model is established which expects that life stressors impact depressive symptoms indirectly rather than directly by increasing sleep disturbances, while sleep disturbances directly work to increase depressive symptoms. Three groups of university students, Japanese ( N = 784) and Chinese ( N = 311) students in their native countries and Chinese students living in Japan ( N = 82), were tested to reveal whether the model fits to all of them and whether there are cultural differences on life stressors and sleep disturbance. The participants responded to a set of questionnaires measuring the extent of depressive symptoms (BDI-II), sleep disturbance symptoms (insomnia, hypersomnia, and nightmare), and experience of life stressors. Japanese students reported more severe depressive symptoms than both groups of Chinese, but the Chinese have had experienced more life stressors than Japanese. Also, Japanese students reported severe hypersomnia symptoms than both groups of Chinese but the trend was reversed for nightmare. The statistical model of depression fitted well for all participant groups. Although experience of life stressors showed direct impact on depression, its indirect effect via sleep disturbance was stronger than its direct effect. This suggests that addressing sleep disturbance symptoms at earliest opportunity is an effective procedure to prevent onset of depression for university students. Implementing sleep education programs could be especially effective for this population.
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Deng, Y., G. Wang, W. Li, Y. Zhang, J. Zhao, Z. Zhang, and F. Jiang. "0972 Persistence, Remission, Acquisition Of Sleep Disturbances Contributes To The Transition Of Emotional/behavioral Problems In Preschool Children." Sleep 43, Supplement_1 (April 2020): A369. http://dx.doi.org/10.1093/sleep/zsaa056.968.

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Abstract Introduction Cross-sectional and longitudinal studies have consistently reported associations between sleep disturbances and emotional/behavioral problems in children. However, few studies have examined whether the remission, acquisition of sleep disturbances contribute to the transition of emotional and behavioral problems during preschool years. Methods This study used data from the Shanghai Children’s Health, Education and Lifestyle Evaluation-Preschool (SCHEDULEA-P), a prospective, population-based cohort study of newly enrolled preschoolers in Shanghai kindergartens in Nov. 2016. In total, 17182 children with complete data on parent-reported Strength and Difficulties Questionnaire (SDQ) both at school enrollment(wave 1) and the third year(wave 2) were included in the study. Children’s sleep disturbances were measured using Children Sleep Habit Questionnaire (CSHQ) at both waves. Results The 17182 participants included 8935(52.0%) males, with a mean (SD) age of 3.73(0.29) years at wave 1. 66.9%, 7.2%, 17.4% and 8.5% of these children were divided into persistent sleep disturbance, acquired, remitted group and persistent normal sleep group, respectively. The proportion of persistent, acquired, remitted emotional/behavioral problems and normal group was 13.7%, 9.4%, 21.1%, 55.8%. SDQ scores of acquired sleep disturbances group stayed high at wave 3, while SDQ scores of remitted sleep disturbances group decreased sharply during the preschool years. After adjusted for confounding factors, the odds of remission from emotional/behavioral problems among children who experienced remission of sleep disturbances, who had persistent normal sleep were both much higher compared to those who had persistent sleep disturbances (OR=2.53(2.12-3.01), p&lt;0.001; OR=2.74(2.01-3.75), p&lt;0.001). Meanwhile, the odds of acquisition of emotional/behavioral problems at wave 2 among subjects who newly acquired sleep disturbances at wave 2 and who had persistent sleep disturbances was similarly higher than those who never have sleep disturbances(OR= 2.75, P&lt;0.001 VS OR=2.77, P&lt;0.001). Besides, those who experience remission of sleep disturbances still have 1.48 times the odds of acquisition of emotional / behavioral problems(P=0.006). Conclusion The remission of sleep disturbances contributed to the remission of emotional/behavioral problems, while the emergence of sleep disturbances throughout preschool years increased the risk of the acquisition of emotional/behavioral problems. Support Supported by the Chinese National Natural Science Foundation of China (81773443, 81728017, 81602870, 81601162, 81602868)
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Wu, Mark, Paul Rosenberg, Adam Spira, and Alexandra Wennberg. "Sleep Disturbance, Cognitive Decline, and Dementia: A Review." Seminars in Neurology 37, no. 04 (August 2017): 395–406. http://dx.doi.org/10.1055/s-0037-1604351.

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AbstractApproximately half of older people report sleep disturbances, which are associated with various health conditions, including neurodegenerative disease and dementia. Indeed, 60 to 70% of people with cognitive impairment or dementia have sleep disturbances, which are linked to poorer disease prognosis. Sleep disturbances in people with dementia have long been recognized and studied; however, in the past 10 years, researchers have begun to study disturbed sleep, including sleep fragmentation, abnormal sleep duration, and sleep disorders, as risk factors for dementia. In this review the authors summarize evidence linking sleep disturbance and dementia. They describe how specific aspects of sleep (e.g., quality, duration) and the prevalence of clinical sleep disorders (e.g., sleep-disordered breathing, rapid eye movement sleep behavior disorder) change with age; how sleep parameters and sleep disorders are associated with the risk of dementia; how sleep can be disturbed in dementia; and how disturbed sleep affects dementia prognosis. These findings highlight the potential importance of identifying and treating sleep problems and disorders in middle-aged and older adults as a strategy to prevent cognitive decline and dementia. The authors also review recent evidence linking sleep disturbances to the pathophysiology underlying dementing conditions, and briefly summarize available treatments for sleep disorders in people with dementia.
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Daniel, L. C., Y. Gross, L. Meltzer, C. Forrest, and L. Barakat. "0981 Sleep Practices In Pediatric Cancer—Does Sleep Hygiene Matter For Reducing Cancer Symptom Burden?" Sleep 43, Supplement_1 (April 2020): A372—A373. http://dx.doi.org/10.1093/sleep/zsaa056.977.

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Abstract Introduction Sleep disturbances are common during pediatric cancer treatment and recent evidence suggests a correlation between sleep and symptom burden. Improving nighttime sleep may impact patients’ ability to cope with symptoms. The current study tests the interaction between sleep hygiene and sleep disturbances in predicting cancer-related symptoms to determine if the relationship between sleep and symptoms is different for patients with better sleep hygiene. Methods 102 caregivers of children with cancer (ages 5-17, M=10.12, SD=4.02; 58% female) completed parent-proxy Pediatric Sleep Practices Questionnaire (yielding routine consistency and sleep opportunity scores) and measures of cancer-related symptoms (PROMIS Sleep Disturbance, Fatigue, and Pain Interference; PedsQL—Cancer Module-Nausea subscale). The interaction between sleep disturbances and sleep hygiene (consistency, opportunity) on each symptom (pain, nausea, fatigue) were tested using PROCESS moderation. Results 81% of caregivers report that their child receives sufficient sleep but only 12% reported regular consistent sleep patterns/routines. Sleep opportunity was not related to sleep disturbances or cancer-related symptoms, but more routine consistency was related to fewer sleep disturbances (r=.30, p=.003). The interaction between sleep disturbances and routine consistency significantly predicted pain interference [R2=.16, F(3, 98)=6.37, p&lt;.001; Bint =-0.17, p=.028] and nausea [R2=.16, F(3, 98)=6.47, p&lt;.001; Bint=0.46, p=.004]. The interaction between sleep disturbances and sleep opportunity significantly predicted nausea [R2=.15, F(3, 98)=5.76, p=.001; Bint =0.68, p=.016] but not pain interference. Both interaction models predicting fatigue were not significant. Conclusion The sleep/pain and sleep/nausea relationships are stronger in patients with more consistent sleep routines and the sleep/nausea relationship is also stronger in patients with sufficient/well-timed sleep opportunities. Sleep and fatigue were moderately related across all levels of both sleep hygiene components. Clinical interventions that target sleep hygiene together with sleep disturbances such as nighttime awakenings and poor sleep quality may be more effective in addressing cancer-related symptoms such as pain and nausea. Support This work was supported in part by funding from the Patient-Centered Outcomes Research Institute (PCORI-D-17-00187; PI Christopher Forrest).
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Nur'aini, Nur'aini, Sri Sofyani, Supriatmo Supriatmo, and Iskandar Z. Lubis. "Comparing sleep disorders in urban and suburban adolescents." Paediatrica Indonesiana 54, no. 5 (October 30, 2014): 299. http://dx.doi.org/10.14238/pi54.5.2014.299-304.

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Background Sleep disturbances commonly occur in adolescents. Socioeconomic levels, lifestyle, and urban or suburban environments influence the sleep patterns of adolescents. The modernization process in urban environments is marked by the development of information technology media, and the lack of parental monitoring potentially influencing adolescent sleep disturbances. Sleep disturbances may affect children's physical growth, as well as their emotional, cognitive, and social development.Objective To assess for sleep disorders in urban and suburban adolescents, and to determine the factors that influence the prevalence of sleep disturbances.Methods A cross-sectional study was conducted on 12 to 15-year-old junior high school students in urban (n=350) and suburban (n=350) environments in the city of Medan, North Sumatera. The study was undertaken from May to June 2010 using the Sleep Disorders Scale for Children (SDSC), a set of questionnaires. The SDSC was filled out by parents based on what they remembered about their children's sleep patterns in the prior 6 months.Results In the urban group, there were 133 (38.0%) subjects with sleep disturbances, 182 (52.0%) were borderline, and 35 (10.0%) were normal. In the suburban group, there were 132 (37.7%) subjects with sleep disturbances, 180 (51.4%) were borderline, and 38 (10.9%) were normal. The most influential factors for sleep disturbances in urban and suburban youth were environmental noise (P=0.001) and consuming beverages that contain caffeine (P=0.001). There were three types of sleep disorders that significantly found more in urban adolescents: disorders of initiating and maintaining sleep, disorders of excessive somnolence, and sleep hyperhidrosis.Conclusion The prevalence of sleep disturbances do not differ between urban and suburban adolescents. Howevet; there are significant differences in the types of sleep disorders experienced. The most influential factors on sleep disturbance in both areas are environmental noise and consuming beverages that contain caffeine.
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Lee, Young-Ji, Bong-Jo Kim, Cheol-Soon Lee, Boseok Cha, So-Jin Lee, Jae-Won Choi, Eunji Lim, Nuree Kang, and Dongyun Lee. "Application of Transcranial Direct Current Stimulation in Sleep Disturbances." Chronobiology in Medicine 4, no. 4 (December 31, 2022): 141–51. http://dx.doi.org/10.33069/cim.2022.0030.

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Sleep disturbances are common across all age groups, and they encompass a broad range of impairments of daytime functioning and comorbid various clinical conditions. However, current treatment methods for sleep disturbances have several limitations. As the ‘top-down’ pathway is known to play an important role in sleep-wake regulation, and as neuronal activity abnormalities have been reported as a potential pathological mechanism of sleep disturbances, the use of non-invasive brain stimulation—such as transcranial direct current stimulation (tDCS) in treating sleep disturbances—has emerged. In the present review, we first explain the mechanism of tDCS, and we also introduce recent studies that have applied tDCS to sleep disorders, along with other sleep-related tDCS studies. In conclusion, many studies have achieved improvements in sleep state, although some of these studies have reported inconsistent effects of tDCS according to the protocol and the conditions used. Further studies are needed to explore the optimal protocols to use when applying tDCS in each sleep disturbance and to enhance the evidence on the clinical efficacy of tDCS.
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Sipilä, Reetta M., and Eija A. Kalso. "Sleep Well and Recover Faster with Less Pain—A Narrative Review on Sleep in the Perioperative Period." Journal of Clinical Medicine 10, no. 9 (May 7, 2021): 2000. http://dx.doi.org/10.3390/jcm10092000.

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Sleep disturbance, pain, and having a surgical procedure of some kind are all very likely to occur during the average lifespan. Postoperative pain continues to be a prevalent problem and growing evidence supports the association between pain and sleep disturbances. The bidirectional nature of sleep and pain is widely acknowledged. A decline in sleep quality adds a risk for the onset of pain and also exacerbates existing pain. The risk factors for developing insomnia and experiencing severe pain after surgery are quite similar. The main aim of this narrative review is to discuss why it is important to be aware of sleep disturbances both before and after surgery, to know how sleep disturbances should be assessed and monitored, and to understand how better sleep can be supported by both pharmacological and non-pharmacological interventions.
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Deepak, Pavan. "Sleep Disturbance in Gynaecologic Malignancies-an Overview." Gynecology and Obstetrics Open Access Open Journal I, no. 2 (November 11, 2020): 29–32. http://dx.doi.org/10.33169/gyne.obste.gaooaoj-i-107.

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Sleep plays a pivotal role in maintaining homeostasis and one of a few foremost determinants of Quality of Life. Quality of life is a well-studied topic in oncology and various measures are taken to improve quality of life in this setting, in order to achieve therapeutic outcome and compliance in general in cancer patients. Sleep disturbances and disruption in circadian rhythm is among a few common presenting complaints of patients with malignancy and affects between 30% to 75% of newly diagnosed or recently treated cancer patients,1 which are reported as double that of the general population, paving the way for decreased compliance and inefficacy of therapy and pose as a detriment to general well-being, and quality of life. It is evident that mood disorders and sleep disturbances are more prevalent in females (1.3 to 1.8 times more than men),2 one may theorize that the prevalence of sleep disturbance in gynaecologic malignancies is greater than that of general population. Sleep disturbances in gynaecologic cancer patients often include difficulty in initiation of sleep, frequent awakening, difficulty in staying asleep, and restless leg syndrome. Systematic research on various sleeps disorders and their therapeutic approach in gynaecologic cancers in general is lacking. This article aims at elucidating and giving overview of sleep pattern changes in gynaecologic malignancies and therapeutic approaches to foster better sleep in this subset of population. This article also emphasizes the need to envisage the treatment strategies targeting cytokines and cortisol in improvement of sleep parameters in gynaecologic malignancies.
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Vance, David E., and Joe W. Burrage. "Sleep Disturbances and Psychomotor Decline in HIV." Perceptual and Motor Skills 100, no. 3_suppl (June 2005): 1004–10. http://dx.doi.org/10.2466/pms.100.3c.1004-1010.

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Sleep disturbances may contribute to cognitive and psychomotor impairments. 50 HIV-positive and 50 HIV-negative adults were assessed on cognitive performance and sleep hygiene. The HIV-positive group performed more poorly on cognitive measures; however, no group differences were found for the sleep variables. In the HIV-positive group, indicators of sleep disturbance were correlated to various measures of cognitive functioning and depression.
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Dule, Aman, Mustefa Mohammedhussein, and Mohammedamin Hajure. "Impact of Sleep Disturbances on the Quality of Life Among Schizophrenic Out-patients of Jimma University Medical Center, Southwest Ethiopia: Hospital Based Cross-sectional Study." Open Public Health Journal 13, no. 1 (December 18, 2020): 684–91. http://dx.doi.org/10.2174/1874944502013010684.

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Aim: Current study was aimed to assess the impacts of sleep disturbances on patient’s quality of life. Background: Schizophrenia is a syndrome, which affects sleep. Up to 80% of schizophrenic patients complain of sleep disturbances which affect the quality of life Objectives: To assess the association of sleep disturbances and quality of life and other contributing factors among schizophrenic patients on follow-up treatment at Jimma University Southwest Ethiopia. Methods: A cross-sectional study with a consecutive sampling of 411 out-patients at Jimma University medical center was employed from April 21-June 20, 2019. Sleep disturbances and the quality of life were assessed by Pittsburgh sleep quality index and WHOQOL-BREF, respectively. Epi data version 3.1 and SPSS version 23.0 software was used. Chi-square and independent samples t-test were used for association and P-value < 0.05 was considered for statistical significance. Results: Most participants had sleep disturbances and the mean score of positive scale on PANSS was higher for patients with sleep disturbances. About one-fourth of the patients had very good subjective sleep quality and > 85% of sleep efficiency was reported by 139 participants. More than half (51.1%) of the subjects had used sleep medication and the majority (64.7%) of them were reported daytime dysfunctions in the past month. The social domain (M±SD=3.92±2.51, t=8.46, p= <0.001, eta2=0.15) and overall WHOQOL (M±SD=57.60±16.87, t=9.24, p= < 0.001, eta2= 0.17) score had a large difference of means and about 15% and 17% of the variance in sleep disturbance have been explained. Conclusion: Generally, the finding of the current study was in agreement with most of the previous studies and sleep disturbances respectively moderate to significant effects on the patient’s quality of life.
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Song, Zicheng, Rongzhen Jiang, Changbin Li, Feng Jin, and Minfang Tao. "Menopausal Symptoms and Sleep Quality in Women Aged 40–65 Years." BioMed Research International 2022 (August 9, 2022): 1–6. http://dx.doi.org/10.1155/2022/2560053.

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The study examined the relationship between menopausal symptoms and sleep disturbances and the related influencing factors. Methods. We recruited women aged 40-65 years who attended the menopause clinic at Shanghai Jiao Tong University’s Sixth People’s Hospital from February 2011 to November 2019. The Menopause Rating Scale (MRS) was used to collect women’s menopausal symptoms, and the Pittsburgh Sleep Quality Index (PSQI) was used to evaluate the subjects’ sleep condition. We used logistic regression models to identify the relationship between menopausal symptoms and sleep quality. Results. A total of 1341 participants were recruited in this study. The most frequent three symptoms assessed by MRS were fatigue (72.9%), sleep disturbance (67%), and hot flashes with night sweats (65%). Participants’ age was significantly associated with the severity of menopausal syndrome ( P < 0.01 ). According to the PSQI sleep evaluation, 66.9 percent of participants had sleep disturbances ( PSQI > 5 ). Logistic regression analysis revealed that women with mild, moderate, or severe menopausal syndrome had a 3-, 7-, and 17-fold increased chance of having sleep disturbances compared to women without menopausal syndrome. Conclusion. Women aged 40–65 years were found to have a significantly higher risk of menopausal syndrome and sleep disturbances.
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Sun, Yishi, Isabelle Laksono, Janannii Selvanathan, Aparna Saripella, Mahesh Nagappa, Chi Pham, Marina Englesakis, Philip Peng, Charles Morin, and Frances Chung. "679 Prevalence of Sleep Disturbances in Patients with Chronic Non-cancer Pain: A Systematic Review and Meta-Analysis." Sleep 44, Supplement_2 (May 1, 2021): A265—A266. http://dx.doi.org/10.1093/sleep/zsab072.677.

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Abstract Introduction In individuals with chronic pain, sleep disturbances have been suggested to increase suffering, perception of pain, and to negatively affect long-term prognosis. This systematic review and meta-analysis aims to determine the pooled prevalence of sleep disturbances in chronic non-cancer pain patients with no other sleep disorders, using the patient-rated questionnaires Pittsburgh Sleep Quality Index (PSQI) and Insomnia Severity Index (ISI). Methods Multiple databases were searched for studies reporting the prevalence of sleep disturbances in chronic pain patients. Chronic pain was defined as pain &gt;3 months. Comorbid sleep disorders such as sleep disordered breathing and restless leg syndrome were excluded. Sleep disturbances were defined using the PSQI cutoff of &gt; 5 (poor sleep quality) and ISI ≥ 8 (subthreshold to clinical insomnia). The meta-analysis was conducted to examine the pooled prevalence of PSQI and ISI data using the inverse-variance random-effects model and to examine mean differences in PSQI scores. Results The systematic search resulted in 25,486 articles and 20 were included for analysis. In 12 studies using PSQI, the pooled prevalence of sleep disturbance was 75.3% among 3,597 chronic pain patients (mean age 53 ± 12 years; 74% female). In eight studies using ISI, the pooled prevalence was 72.9% among 2,578 chronic pain patients (mean age 63 ± 12 years; 57% female). The meta-analysis showed a significant mean difference of 2.75 (p &lt; 0.001) in the global PSQI score between the chronic pain group versus the non-chronic pain group. The meta-analysis also showed a significant mean difference in the scores of four of seven PSQI components: sleep latency, sleep efficiency, sleep duration, and sleep disturbances (p &lt; 0.05). Conclusion In chronic pain patients, the pooled prevalence of sleep disturbances as measured by PSQI (75.3%) and ISI (72.9%) studies was much higher than those reported for the general population. The relatively high prevalence of sleep disturbances in chronic pain patients emphasizes the importance of further characterizing the relationship between sleep and chronic pain. Support (if any):
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Isaac, Fadia, Samia Toukhsati, Mirella Di Benedetto, and Gerard Kennedy. "A Systemic Review of the Impact of Wildfires on Sleep Disturbances." International Journal of Environmental Research and Public Health 18, no. 19 (September 27, 2021): 10152. http://dx.doi.org/10.3390/ijerph181910152.

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Wildfires present a serious risk to humans as well as to the environment. Wildfires cause loss of lives, economic losses, expose people to personal as well as collective trauma, and compromise the mental health of survivors. Sleep disturbances are highly prevalent following a traumatic event; however, their prevalence is not well established amongst those confronted by natural disasters such as wildfires. The aim of this systematic review is to synthesise the empirical findings pertaining to wildfires and the prevalence of sleep disturbances in the general community affected by this natural disaster. We searched EBSCO, PsychINFO, Medline, SpringerLink, CINAHL Complete, EMBASE, PubMed, Scopus and Cochrane Library between January 2012 and March 2021. Five studies met the inclusion criteria. Findings from this systematic review suggest that sleep disturbances, assessed one to ten months following the fires, are highly prevalent in wildfire survivors, with insomnia (ranging between 63–72.5%) and nightmares (ranging between 33.3–46.5%), being the most prevalent sleep disturbances reported in this cohort. Results also highlight the significant associations between sleep disturbances and post-traumatic symptoms following the trauma of wildfires. There is a possible link between sleep disturbance prevalence, severity of, and proximity to fires.
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Orbea, Cinthya Pena, Brittany Lapin, Irene Katzan, Kristin Englund, Nancy Foldvary-Schaefer, and Reena Mehra. "0735 Sleep Disturbances in Post-Acute Sequelae of COVID-19 (PASC)." Sleep 45, Supplement_1 (May 25, 2022): A321. http://dx.doi.org/10.1093/sleep/zsac079.731.

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Abstract Introduction Sleep difficulties and fatigue are highly prevalent, pervasive symptoms reported in patients with Post-Acute Sequelae of COVID-19 (PASC). As little is known of the predictors and severity of PASC-related sleep disturbance and intersection with fatigue, we leverage systematic data collected from the Cleveland Clinic ReCOVer Clinic for further elucidation Methods Analysis of data collected from Cleveland Clinic ReCOVer Clinic patients (February-November 2021) who completed the Patient-Reported Outcomes Measurement (PROMIS) Sleep Disturbance and PROMIS Fatigue questionnaires was performed. Data were extracted from the Cleveland Clinic COVID-19 registry and the electronic health record.PROMIS scores are standardized to the general U.S. adult population on a T-scale with mean 50±10. PROMIS sleep disturbance and fatigue T-scores ≥60 indicates at least moderate disturbance and ≥70 indicate severe disturbance. T-test and Chi-square tests were used to examine cross-group differences. Multivariable logistic regression adjusted for age, race, sex, and body mass index(kg/m2) was performed to investigate factors associated with sleep disturbance severity. Results Out of 1321, 682 patients completed the PROMIS Sleep Disturbance questionnaire with age 49.8±13.6, 75.2% female and 12.3% black race. Average T-scores were 57.7±8.3, 281 (41.2%) patients reported at least moderate sleep disturbance and 50 (7.3%) reported severe sleep disturbances. Average PROMIS Fatigue T-score was 63.0±9.2; 68.6% patients reported at least moderate fatigue, 22.6% reported severe fatigue. Patients with moderate-severe compared to normal-to-mild sleep disturbances respectively had higher BMI (32.3±8.7 vs 30.9±7.5, p=0.049), were more likely of black race (40.0±10.0 vs 41.0±15.7,p=0.010), had worse eneral Anxiety Disorder (GAD)-2 questionnaires scores (2.8±2.1 vs 1.6±1.7,p&lt;0.001), Patient Health Questionnaire (PHQ)-2 scores (2.8±2.0 vs 1.6±1.7,p&lt;0.001) and PROMIS fatigue scores (66.7±7.8 vs 60.4±9.1,p&lt;0.001) with no difference in age, sex, or hospitalization due to COVID-19. In the adjusted model, black race was associated with moderate-severe sleep disturbance (OR=3.42, 95%CI:1.64-7.13). Conclusion The prevalence of moderate to severe sleep disturbances reported by patients presenting for PASC was very high i.e.&gt;40% and associated with obesity, black race and mood symptoms. Notably, after adjustment for demographics, black race conferred a 3-fold higher odds of moderate-severe sleep disturbance emphasizing the need to characterize race-specific determinants and disparities in COVID-19 survivors. Support (If Any)
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Chen, Pin-Yuan, Hsiao-Yean Chiu, and Pei-Ching Lin. "QOLP-28. PREOPERATIVE SLEEP DISTURBANCE AND ITS ASSOCIATION WITH QUALITY OF LIFE IN ADULT BRAIN TUMOR PATIENTS." Neuro-Oncology 22, Supplement_2 (November 2020): ii181. http://dx.doi.org/10.1093/neuonc/noaa215.753.

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Abstract BACKGROUND Sleep disturbances are common complaints in adult brain tumor patients and impact their quality of life profoundly. The prevalence and pattern of preoperative sleep disturbances are still unknown. MATERIAL AND METHOD There were 36 adult patients with primary brain tumors who were recruited before craniotomy. All participants completed a battery of questionnaires, including the Athens Insomnia Scale, Epworth Sleepiness Scale, Pittsburgh Sleep Quality Index, Brief Fatigue Inventory, Hospital Anxiety, and Depression Scale, Morningness-Eveningness Questionnaire, and EORTC-QLQ-BN20. Actigraphy was put on a non-dominant wrist for obtaining objective sleep parameters, such as the dichotomy index. RESULT The prevalence of preoperative insomnia, poor sleep quality, excessive daytimes sleepiness, and circadian disruption were all high but similar between benign and malignant brain tumor groups. Patients with glioma had poorer quality of life. Insomnia was the only sleep disturbance that significantly associated with quality of life in a multivariate linear regression modal. CONCLUSION Sleep disturbances are common in adult brain tumor patients. Insomnia worse the quality of life of these patients. A further longitudinal investigation of sleep disturbances and quality of life in brain tumor patients is worthful.
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Zaidi, Syed-Nadeem. "Post-operative sleep disturbances." Morecambe Bay Medical Journal 8, no. 2 (October 1, 2018): 47–49. http://dx.doi.org/10.48037/mbmj.v8i2.16.

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In this review we will discuss some very basic physiologic concepts about normal sleep. Causes of postoperative sleep disturbances, its clinical significance and some remedies to restore sleep in the post-operative period will also be discussed.
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Lee, Suonaa, Kyung Mee Park, Woo Jung Kim, and Eun Lee. "Clinical Characteristics of HIV-Infected Patients With Sleep Disturbance." Chronobiology in Medicine 4, no. 3 (September 30, 2022): 115–20. http://dx.doi.org/10.33069/cim.2022.0020.

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Objective: This study aims to examine clinical characteristics and to identify possible risk factors of sleep disturbances in people living with HIV (PLWH).Methods: All research data of patients who were first diagnosed with HIV/AIDS from January 1, 2012 to December 31, 2021 and complained of sleep disturbance at least once were retrospectively reviewed by the Severance Clinical Research Analysis Portal (SCRAP) service of Severance hospital. The presence of sleep disturbance was evaluated based on whether insomnia disorder diagnosis code was included or whether insomnia medication was prescribed. The patients were divided into either the group with sleep disturbance within 3 months (SDW3) and the group with after 3 months (SDA3). All data were reported using descriptive statistics.Results: Of the 674 patients diagnosed with HIV during the period, 56 patients experienced sleep disturbances at least once and approximately 50% of patients have experienced sleep disturbance in the first 3 months after HIV diagnosis. CD4+ cell count at the time of first onset of sleep disturbance was significantly lower (p=0.03) and HIV viral load at the time of first onset of sleep disturbance was significantly higher (p<0.001) in SDW3 group. SDW3 patients showed higher rates of opportunistic infections compared to SDA3 patients.Conclusion: The current study suggests that further investigation of the underlying pathophysiology of sleep disturbance and association with immunological changes for early diagnosis and treatment of sleep disturbance in PLWH.
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Bernert, Rebecca A., Thomas E. Joiner, Kelly C. Cukrowicz, Norman B. Schmidt, and Barry Krakow. "Suicidality and Sleep Disturbances." Sleep 28, no. 9 (September 2005): 1135–41. http://dx.doi.org/10.1093/sleep/28.9.1135.

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Al-Rawashdeh, Sami Y., Terry A. Lennie, and Misook L. Chung. "The Association of Sleep Disturbances With Quality of Life in Heart Failure Patient–Caregiver Dyads." Western Journal of Nursing Research 39, no. 4 (October 7, 2016): 492–506. http://dx.doi.org/10.1177/0193945916672647.

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Sleep disturbance is common in patients with heart failure and their family caregivers. The purpose of this study was to determine whether sleep disturbances of patients and their spousal caregivers predicted their own and their partners’ quality of life (QoL) in 78 heart failure patient–spousal caregiver dyads. Sleep disturbance was assessed using a composite score of four common sleep complaints. QoL was assessed by the physical and mental well-being subscales of the Short-Form 12 Health Survey. The multilevel dyadic actor–partner interdependence model analysis was used to determine the association between sleep disturbance and QoL. Each individual’s sleep disturbance predicted their own poor physical and mental well-being while spousal caregivers’ sleep disturbance predicted their partners’ mental well-being. Results indicated that patients’ mental well-being is sensitive to their spouses’ sleep disturbance. Interventions targeting improving sleep and QoL may have to include both patients and spousal caregivers.
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White, Kaylin, Liana Dunietz, D’Angela Pitts, David Kalmbach, and Louise O’Brien. "544 Burden of Sleep Disturbance in Black Pregnant Women." Sleep 44, Supplement_2 (May 1, 2021): A214—A215. http://dx.doi.org/10.1093/sleep/zsab072.542.

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Abstract Introduction Black women disproportionately experience poor perinatal outcomes compared to other racial/ethnic groups. Poor sleep has emerged as a strong contributor to adverse pregnancy outcomes and, in the non-pregnant population, sleep-wake disturbances have a high prevalence with often greater severity among Blacks. Nonetheless, the majority of studies have included largely White populations which has restricted our understanding of race-specific burdens and morbidities of sleep disturbance. The goal was to describe the burden of sleep-wake disturbance in Black pregnant women and associations with pregnancy outcomes. Methods Black women at least 18years and &gt;28 weeks pregnant were recruited from prenatal clinics. All women completed questionnaires about their sleep including the presence and timing of habitual-snoring (pre-pregnancy or pregnancy-onset), the Epworth Sleepiness Scale (ESS), and the General Sleep Disturbances Scale (GSDS) to determine poor sleep quality and poor daytime function as well as symptoms of insomnia. We also analyzed three commonly-reported sleep problems as individual question items (difficulty getting to sleep, wake up during sleep period, and wake up too early at the end of a sleep period). Demographic information and diagnoses were abstracted from medical records. Results Overall, 235 women enrolled; mean age was 27.6 + 6.2 years, mean BMI 31.7 + 9.8kg/m2, and 64% were in receipt of Medicaid. Eighty-percent of women reported &gt;three sleep-wake disturbances, and almost half experienced a burden of &gt;five disturbances. Women with pregnancy-onset habitual-snoring (but not those with pre-pregnancy habitual-snoring) had increased odds of poor sleep quality aOR 8.2 (95% CI 1.9, 35.9), trouble staying asleep aOR 3.6 (95% CI 1.0, 12.5), waking up too early aOR 2.7 (95% CI 1.1, 6.2), excessive daytime sleepiness aOR 2.3 (95% CI 1.1, 4.7), and poor daytime function aOR 8.7 (95% CI 2.5, 29.9). In contrast, women with pre-pregnancy habitual-snoring had increased odds for chronic hypertension, preterm delivery and fetal growth restriction; aOR 2.6 (95% CI 1.1, 6.3), aOR 2.8 (95% CI 1.1, 6.9), and aOR 5.1 (95% CI 1.7, 15.2), respectively. Conclusion Black women have a significant burden of sleep-wake disturbances. These findings highlight the excess risk that habitual-snoring confers to sleep-wake disturbances and perinatal outcomes in an infrequently studied yet highly vulnerable population. Support (if any) NIH NHLB-IHL089918
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44

Khomeini, Khomeini, Dody E. Dody E, and Erkadius Erkadius. "Hubungan Penurunan Kadar Natrium Terhadap Gangguan Pola Tidur Pasca TURP (Transurethral Resection of The Prostate)." Jurnal Kesehatan Andalas 2, no. 1 (January 1, 2013): 09. http://dx.doi.org/10.25077/jka.v2i1.56.

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AbstrakLatar Belakang. TURP merupakan tindakan operasi endoskopi standar baku untuk penatalaksanaan BPH yang memerlukan tindakan bedah. Dalam pengamatan sehari hari pasien pasca TURP mengeluhkan gangguan pola tidur pasca tindakan. Belum dilaporkan angka kejadian gangguan pola tidur pasca TURP. Salah satu masalah yang mungkin sebab yaitu terjadinya penurunan kadar natrium akibat imbibisi air irigant ke intra vaskuler. Penurunan kadar natrium dapat menyebabkan gangguan neurologis yang mengganggu pola tidur. Penurunan natrium berlanjut dapat menjadi sindroma TURP. Metodologi. Penelitian ini penelitian cross sectional, semua pasien BPH dilakukan pemeriksaan natrium dan diberikan kuesioner gangggan pola tidur. Setelah TURP dilakukan pemeriksaan natrium pasca TURP dan kuesioner kembali. Jumlah distribusi gangguan pola tidur dan kadar natrium disajikan dalam bentuk tabel. Tiap variabel dilakukan analisa dan uji statistik dengan menggunakan T-test, chisquare dan Fisher. Hasil. Didapatkan pasien dengan gangguan pola tidur 41%.. Didapatkan perbedaan bermakna hubungan antara umur pasien dengan gangguan pola tidur pada tabel 3 ( chisquare 1.999027 ). Tidak didapatkan perbedaan bermakna hubungan antara pekerjaan pasien dengan gangguan pola tidur pada tabel 5 (Chi square: 1.242). Tidak didapatkan perbedaan bermakna hubungan antara pendidikan pasien dengan gangguan pola tidur pada tabel 6 (chisquare 1,242). Tidak didapatkan perbedaan bermakna hubungan antara lama operasi dengan gangguan pola tidur tabel 7 (chisquare 3,306). Didapatkan lama operasi <1jam terjadi penurunan kadar natrium 3,783 + 2,235mmol/L sedangkan operasi > 1 jam terjadi penurunan natrium 6,692 + 6,047dengan perbedaan bermakna secara statistic.( t=2,087 ; P 0,044). Tidak didapatkan perbedaan bermakna hubungan antara jumlah cairan irigasi dengan gangguan pola tidur pada tabel 8 ( chi square 2,520). Tidak didapatkan perbedaan bermakna antara jumlah cairan irigasi dengan penurunan natrium pada gambar 2 (F1,35 = 3,004). Didapatkan Mean natrium sebelum TURP 139,3 + 3,7 dan natrium sesudah TURP 134,Kata kunci: Gangguan pola tidur, Penurunan kadar natrium, TURPAbstractBackground. TURP is the gold standard endoscopic surgery for the treatment of benign enlargement of the prostate gland that requires surgery. In daily observations after TURP patients often complain of sleep patterns disturbances . Incidence has not been reported sleep pattern disturbance after TURP. One problem that may cause sodium levels are decreasing as a result of water imbibition irigant to intra vascular. Declining levels of sodium cause neurological disorders that can disrupt sleep patterns. The decline continues of Sodium level could be a TURP syndrome.Methodology. This study is a cross sectional study, all patients with diagnose Benign Prostate Hypertrophi should be check sodium level and get questionnaire sleep patterns disturbances. After TURP check sodium level and questionnaires again . The number of distribution of sleep pattern disturbances and the sodium content is presented in tabular form. Each variabel was analize and statistic test with T-test, Fischer and chisquare.Results. Obtained patients with sleep patterns dsiturbances 41% . Achieved significant differences between relationship age of the patient with sleep patterns disturbances in Table 3 (chisquare 1.999027). No significant differences in the relationship between the work of patients with sleep patterns disturbances in table 5 (Chi square: 1,242). No significant differences in the relationship between the education of patients with sleep patterns dsiturbances in table 6 (chisquare 1.242). No significant differences in the relationship between long operation with sleep pattern disturbance in table 7 (chisquare 3.306). In this research, the operating time <1 hr make a decrease sodium levels 3.783 + 2.235 mmol / L, while operating > 1 hour decrease sodium 6.692 + 6.047 mmol/L with a statistically significant difference. (T = 2.087, P 0.044). No significant differences in the relationship between irrigation fluid with sleep patterns indisturbances table 8 (chi square 2.520). No significant differences between the amount of irrigation fluid with decreased of sodium level in figure 2 (F1, 35 = 3.004). Obtained Mean of sodium before TURP 139.3 + 3.7 and sodium after TURP 134.4 + 5.3 mmol / L. No significant differences between the relationship of sodium before TURP in table 9 (chi square 1.286) and post-TURP with decreased of sodium levels in table 10 (chi square 1.286) with sleep patterns disturbances after TURP. In getting significant differences between sleep patterns disturbances with decreases sodium levels in table 11 (Fischer: 0.0000118)Conclusion. The incidence of sleep patterns disturbances after TURP 41%. Sleep patterns disturbancesb after TURP is associated with decreased levels of sodium and operating time. No significant difference was found between age, occupation, education, with sleep patterns disturbances after TURP.Keywords:sleep patterns disturbances , decrease sodium levels, TURP.
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45

Antsyborov, Andrey Viktorovich, Anna Valerievna Kalinchuk, and Irina Vladimirovna Dubatova. "Sleep and Depression: What We Know and What to Learn?" Interactive science, no. 7 (53) (October 20, 2020): 33–49. http://dx.doi.org/10.21661/r-551927.

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Presently, a lot of data indicate that the disturbance of mechanisms underlying the regulation of sleep-waking cycle coincides with the mechanisms underlying the development of depression. The disturbance of circadian rhythms is one of the core factors in the genesis of the most affective disorders including depression, which indicates the role of the internal biological clock in the pathophysiology of affective disorders. The episodes of depression, mania or hypomania may result from the disturbances in endogenous biological timing. In this review, we have summarized the literature data obtained in animal models or in the patients with affective pathology, in which the connection between the function of sleep and depression was demonstrated. Specifically, we highlight the mechanisms underlying sleep dysfunction during depression (imbalance of circadian rhythms, melatonin metabolism and mechanisms of neuroinflammatory dysregulation) and provide an evidence for the link between sleep function and depression (sleep disturbances during depressive episodes, the effects of pharmacotherapy, chronotherapy, the effect of sleep deprivation, comorbidity of obstructive sleep apnea and depression).
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46

Argiansya, Fandi, Rismarini Soedjadhi, Raden Muhammad Indra, and Yudianita Kesuma. "Electronic Media Use and Sleep Disorders among Adolescents during the COVID-19 Pandemic." Sleep Disorders 2021 (August 19, 2021): 1–5. http://dx.doi.org/10.1155/2021/2096944.

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Background. One of the negative impacts of electronic media use is the occurrence of sleep disturbances. Due to the COVID-19 pandemic, the use of electronic media in families, including in adolescents, has been increasing. Objective. This study was aimed at describing the association between electronic media use and sleep disturbances in adolescents in Palembang. Methods. A cross-sectional study was conducted in January to February 2021. Participants were 14–17-year-old high school students who completed a questionnaire to assess electronic media use and a Sleep Disturbance Scale for Children (SDSC) questionnaire to assess sleep disturbances. Results. One hundred and fifty-seven participants enrolled in this study. The majority of the participants were 16 years old or older (56.7%) and used smartphones (93%) with a median of media use of 10 hours a day. None of the participants’ characteristic variables showed statistically significant correlations. Similarly, none of the electronic media use variables showed statistically significant correlations. Conclusion. Most of adolescents in this study have used electronic media for more than 6 years, with median use of 10 hours per day, for noneducative purposes. Despite findings that most of them experience sleep disturbances, there was no statistically significant association between electronic media use and sleep disturbances in adolescents.
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47

Chasens, Eileen R., Susan M. Sereika, and Lora E. Burke. "Daytime Sleepiness and Functional Outcomes in Older Adults With Diabetes." Diabetes Educator 35, no. 3 (April 14, 2009): 455–64. http://dx.doi.org/10.1177/0145721709333857.

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Purpose This secondary analysis examined the effect of excessive sleepiness on daytime function in older adults with diabetes from the National Sleep Foundation's Sleep and Aging poll. Methods Respondents were older adults (N = 1506; age range, 55-84 years) evaluated by telephone survey on their sleep duration, sleep disturbances, daytime functional outcomes, and self-reported height, weight, and comorbidities. Results Approximately 16% (n = 244) of the sample acknowledged a diagnosis of diabetes; they were older, had more comorbidities, had a higher body mass index (BMI), and were more likely to be sleepy during the daytime than nondiabetic respondents (all P < .05). Respondents with diabetes who reported frequent daytime sleepiness (n = 50; 20%) had significantly (P < .05) higher BMI, lower self-rated health, and more sleep disturbances than those who were not sleepy (n = 194). Sleepy respondents with diabetes also reported more frequent feelings of depression, decreased pleasure in life, naps, feeling drowsy, or dozing off while driving (all P < .05). Excessive sleepiness was significantly associated (P < .001) with an increased risk for depressive symptoms while controlling for BMI, age, and number of comorbidities. Conclusions These results indicate that sleep disturbances affect not only sleep quality but also daytime function in older adults with diabetes.
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48

Kamp, Kendra, Kindra Clark-Snustad, Linda Yoo, Diana Buchanan, Jeffrey Jacobs, Mitra Barahimi, Margaret Heitkemper, and Scott D. Lee. "RELATIONSHIP BETWEEN SELF-REPORTED SLEEP AND DISEASE ACTIVITY DIFFERS BASED ON ENDOSCOPIC OR CLINICAL DISEASE ACTIVITY MEASURES." Inflammatory Bowel Diseases 28, Supplement_1 (January 22, 2022): S77. http://dx.doi.org/10.1093/ibd/izac015.125.

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Abstract BACKGROUND Patients with inflammatory bowel disease (IBD) report more sleep disturbances than healthy controls. Self-reported sleep disturbances have been associated with active clinical disease. Few studies have examined the relationship between self-reported sleep and endoscopic disease activity, and IBD sleep studies have yet to consider the discrepancies that exist between clinical and endoscopic disease measures. The purpose of this pilot study was to examine self-reported sleep based on endoscopic and clinical disease activity among patients with IBD. METHODS Patients with IBD were recruited from a single medical center. Patients ages 18-55 with a scheduled endoscopy were included. Patients completed informed consent, wore a wrist actigraph for 10 days, and answered baseline demographic, clinical disease activity, and sleep questionnaires including Patient-Reported Outcomes Measurement Information System (PROMIS) sleep disturbance, PROMIS sleep-related impairment, and the Pittsburg Sleep Quality Index (PSQI). For both the PROMIS and PSQI, higher scores indicate greater sleep/wake disturbances. Endoscopic disease activity (Mayo or Simple Endoscopic Score) within three months was obtained from the medical record. RESULTS The study included 27 participants with a mean age of 33.3 (SD: 8.2) years and a disease duration of 11 (SD: 7.2) years. The sample predominantly had Crohn’s disease (75%) and 61% were female. Sixty-three percent of the total sample were classified as poor sleepers based on the PSQI. When comparing self-reported sleep based on clinical disease activity, patients with active clinical disease had higher self-reported sleep disturbance (57.3 vs. 49.7, D=1.28) and sleep-related impairment (58.1 vs. 52.8, D=0.51) compared to those with inactive clinical disease. However, self-reported sleep and endoscopic disease activity had the opposite interpretation. Only 40% of patients with active endoscopic disease were poor sleepers compared to 76.5% of patients with inactive endoscopic disease. Patients with active endoscopic disease had lower self-reported sleep disturbance (49.2 vs 52.6, D=-0.53) and sleep-related impairment (49.7 vs. 56.6, D=-0.71) compared to those with inactive endoscopic disease. CONCLUSION The relationship between self-reported sleep and disease activity differs based on the measure of disease activity. Our findings of self-reported sleep disturbances and active clinical disease are similar to previous studies. However, when examining the relationship based on endoscopic disease activity, patients with active endoscopic disease had less self-reported sleep disturbance than patients with inactive endoscopic disease. Further research is needed to better characterize the relationship between sleep and disease activity, and determine the underlying mechanisms related to poor sleep in the IBD population.
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49

Chen, Y., C. Chen, P. J. Strollo, C. Li, W. Ko, C. Lin, and N. Ko. "1027 Differences in Polysomnography-Based Sleep Disorders Between HIV-Infected Persons and Matched Controls." Sleep 43, Supplement_1 (April 2020): A390. http://dx.doi.org/10.1093/sleep/zsaa056.1023.

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Abstract Introduction Sleep disturbance is a prevalent problem among HIV-infected persons. The recognition of comorbid sleep disorders in patients with HIV is currently hampered by limited knowledge of sleep-related symptoms, sleep architecture, and types of sleep disorders. We aimed to compare the differences in sleep-related symptoms and polysomnography-based sleep disorders between HIV-infected persons and controls. Methods The study included 170 men with a Pittsburgh sleep quality index (PSQI) greater than 5, composed of 44 HIV-infected men and 126 male controls who were frequency-matched by sex, age (-/+ 3.0 years) and BMI (-/+ 3.0 kg/m2). For all participants an overnight sleep study using a Somte V1 monitor was conducted. Differences in sleep-related symptoms and sleep disorders between HIV-infected patients and controls were examined using t-tests or Chi-square tests. Results HIV-infected persons with sleep disturbances more often had psychological disturbances (72.7% vs. 40.5%, p&lt;0.001) and suspected rapid eye movement (REM) behavior disorder (RBD) (25.0% vs. 4.8%, p&lt;0.01) than that of controls. The sleep-disordered breathing (SDB) in HIV-infected persons was less common than that in controls (56.8% vs. 87.3%, p&lt;0.001). The mean percentage of REM sleep among HIV-infected patients was higher than that among the controls (20.6% vs. 16.6%, p&lt;0.001). Enuresis was more common in HIV-infected persons than controls (40.9% vs. 22.2%, p=0.02). Conclusion Psychological disturbances and SDB can be the possible explanations of sleep disturbances in HIV-infected persons, in which suspected RBD is notable. Further studies are warranted to examine underlying factors of suspected RBD among HIV-infected persons with sleep disturbances. Support This work was supported by the Ministry of Science and Technology, Executive Yuan of Taiwan [MOST 105-3011-E-006-002], and National Cheng Kung University Hospital [NCKUH-10702022]
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Morse, Anne, and Evin Bender. "Sleep in Hospitalized Patients." Clocks & Sleep 1, no. 1 (February 25, 2019): 151–65. http://dx.doi.org/10.3390/clockssleep1010014.

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Hospitalized patients frequently have disordered and poor-quality sleep due to a variety of both intrinsic and extrinsic factors. These include frequent nighttime intrusions, insomnia related to pain and unfamiliar environments, dark conditions during the day with loss of natural light, and disruption of the natural sleep cycle due to illness. Sleep wake disturbances can result in a deleterious consequence on physical, emotional, and cognitive status, which may impact patient satisfaction, clinical recovery, and hospital length of stay. Despite this, clinicians frequently fail to document sleep disturbances and are generally unaware of the best practices to improve sleep quality in the hospital. A PubMed search was conducted using the terms: (“sleep and hospitalized patients”) and (“sleep and hospitalization”) to review the published data on the topic of sleep in hospitalized medical patients. The search was limited to English-language articles published between 2000 and 2018. Subsequent PubMed searches were performed to clarify the data described in the initial search, including the terms “hospital sleep protocols,” “hospitalized patients sleep documentation,” and “hospitalized patients sleep quality”. The purpose of this review is to discuss sleep disturbances in hospitalized patients with a focus on causes of sleep disturbance, the effect of poor-quality sleep, high risk populations, considerations for surveillance and prevention, and pharmacologic and non-pharmacologic options for treatment.
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