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Journal articles on the topic '(SLS); Direct Powder Extrusion'

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Published: 7 June 2025
Last updated: 2 August 2025

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1

Boniatti, Janine, Patricija Januskaite, Laís B. da Fonseca, et al. "Direct Powder Extrusion 3D Printing of Praziquantel to Overcome Neglected Disease Formulation Challenges in Paediatric Populations." Pharmaceutics 13, no. 8 (2021): 1114. http://dx.doi.org/10.3390/pharmaceutics13081114.

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For the last 40 years, praziquantel has been the standard treatment for schistosomiasis, a neglected parasitic disease affecting more than 250 million people worldwide. However, there is no suitable paediatric formulation on the market, leading to off-label use and the splitting of commercial tablets for adults. In this study, we use a recently available technology, direct powder extrusion (DPE) three-dimensional printing (3DP), to prepare paediatric Printlets™ (3D printed tablets) of amorphous solid dispersions of praziquantel with Kollidon® VA 64 and surfactants (Span™ 20 or Kolliphor® SLS).
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Carreira, Pedro, Fábio Cerejo, Nuno Alves, and Maria Teresa Vieira. "In Search of the Optimal Conditions to Process Shape Memory Alloys (NiTi) Using Fused Filament Fabrication (FFF)." Materials 13, no. 21 (2020): 4718. http://dx.doi.org/10.3390/ma13214718.

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This research was performed so as to investigate the additive manufacturing of NiTi shape memory alloys, which is associated with direct processes, such as selective laser melting. In addition to its expensive production costs, NiTi readily undergoes chemical and phase modifications, mainly as a result of Ni loss during processing as a result of high temperatures. This research explores the potential usefulness of NiTi as well as its limitations using indirect additive processes, such as fused filament fabrication (FFF). The first step was to evaluate the NiTi critical powder volume content (C
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Kleijnen, Rob, Manfred Schmid, and Konrad Wegener. "Production and Processing of a Spherical Polybutylene Terephthalate Powder for Laser Sintering." Applied Sciences 9, no. 7 (2019): 1308. http://dx.doi.org/10.3390/app9071308.

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This work describes the production of a spherical polybutylene terephthalate (PBT) powder and its processing with selective laser sintering (SLS). The powder was produced via melt emulsification, a continuous extrusion-based process. PBT was melt blended with polyethylene glycol (PEG), creating an emulsion of spherical PBT droplets in a PEG matrix. Powder could be extracted after dissolving the PEG matrix phase in water. The extrusion settings were adjusted to optimize the size and yield of PBT particles. After classification, 79 vol. % of particles fell within a range of 10–100 µm. Owing to i
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4

Sing, Swee Leong, Wai Yee Yeong, Florencia Edith Wiria, et al. "Direct selective laser sintering and melting of ceramics: a review." Rapid Prototyping Journal 23, no. 3 (2017): 611–23. http://dx.doi.org/10.1108/rpj-11-2015-0178.

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Purpose This paper aims to provide a review on the process of additive manufacturing of ceramic materials, focusing on partial and full melting of ceramic powder by a high-energy laser beam without the use of binders. Design/methodology/approach Selective laser sintering or melting (SLS/SLM) techniques are first introduced, followed by analysis of results from silica (SiO2), zirconia (ZrO2) and ceramic-reinforced metal matrix composites processed by direct laser sintering and melting. Findings At the current state of technology, it is still a challenge to fabricate dense ceramic components dir
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Tricker, D., M. Jackson, and R. Dashwood. "Direct extrusion of titanium alloy powder." Materials Technology 24, no. 3 (2009): 174–79. http://dx.doi.org/10.1179/106678509x12475882915411.

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Ryabicheva, Lyudmila, Dmytro Usatyuk, and Nikolaj Beloshitskij. "Modeling of Direct Extrusion of Porous Powder Billets." Advanced Materials Research 566 (September 2012): 267–70. http://dx.doi.org/10.4028/www.scientific.net/amr.566.267.

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The computer modeling results for direct extrusion of porous powder billets on a basis of the plasticity theory relations are presented. Distributions of stress-strain state parameters and density during direct extrusion of hollow detail from copper powder billet have obtained. The optimal value of backpressure, that ensures a uniform stress-strain state and given density of detail have found. The dependences of backpressure value from relative depth of cavity and extrusion pressure from backpressure are recommended.
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7

Zubizarreta, C., I. Arribas, S. Giménez, and I. Iturriza. "Softening-Hardening Mechanism in the Direct Hot-Extrusion of Aluminium Compacts." Materials Science Forum 534-536 (January 2007): 837–40. http://dx.doi.org/10.4028/www.scientific.net/msf.534-536.837.

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Powder compacts from two different commercial aluminium powder grades have been densified by direct hot extrusion. The extrusion runs have been carried out at 425 °C, with an extrusion ratio of 1:16 and a ram speed of 1.5 mm/s. Prior to extrusion, some green compacts were presintered (500 °C). The evolution of the extrusion load during the process and the hardness of the final products have been investigated. Additionally, microstructural characterization by X-ray diffraction (XRD), Scanning Electron Microscopy (SEM) and Electron Backscattered Diffraction (EBSD) was carried out in order to und
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8

L. Amorim, Fred, Armin Lohrengel, Volkmar Neubert, Camila F. Higa, and Tiago Czelusniak. "Selective laser sintering of Mo-CuNi composite to be used as EDM electrode." Rapid Prototyping Journal 20, no. 1 (2014): 59–68. http://dx.doi.org/10.1108/rpj-04-2012-0035.

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Purpose – This work is focused on the investigation of direct production of electrical discharge machining (EDM) electrodes through the selective laser sintering (SLS) technique using a new metal-matrix composite material made of molybdenum and a copper-nickel alloy (Mo-CuNi). The influence and optimization of the main SLS parameters on the densification behavior and porosity is experimentally studied. Additionally, EDM experiments are performed to evaluate the electrodes performance under different machining conditions. The paper aims to discuss these issues. Design/methodology/approach – The
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9

Rjabicheva, L. A., and D. A. Usatjuk. "Modeling the evolution of the deformation zone under various extrusion schemes." Izvestiya MGTU MAMI 7, no. 2-2 (2013): 120–24. http://dx.doi.org/10.17816/2074-0530-68103.

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Using the simulation results it was shown an optimal correlation of the size and porosity of powder compacts and also the amount of counterpressure recommended for the production of equal channel angular extrusion of workpieces with high-density of deformation zone that is large enough for subsequent direct extrusion powder of parts with high mechanical properties.The article defines the maximum depth of the cavity in direct extrusion through the research of plasticity resource. This paper describes the developed technology of manufacturing high-density parts of the "glass" type with the consi
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10

Gorenko, М. V. "Chemical Method of Receipt of Powder-Like Mixtures of Copper Crystals (Cu) -Nano, Micro Dispersion of for Reinforcement of Polymeric Compositions are Used as Materials for Printing 3D." Фізика і хімія твердого тіла 17, no. 2 (2016): 269–74. http://dx.doi.org/10.15330/pcss.17.2.269-274.

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We consider possibility of the chemical process of obtaining crystals of copper powder mixtures -nano, micro dispersion of for reinforcement of polymeric compositions are used as materials for printing 3D thermo-extrusion method, is given determination the physic and to mechanical properties of the resulting material, depending on the filler, we offer a method to reduce the porosity of products for the SLS technology, DMLS,investigated kinds of crystal structures of copper (Cu) and crystallization process copper (Cu) with -nano phase in solution H2O.
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11

Bombač, David, Peter Cvahte, Martin Balog, Goran Kugler, and Milan Terčelj. "In-Depth Comparison of an Industrially Extruded Powder and Ingot Al Alloys." Metals 10, no. 11 (2020): 1483. http://dx.doi.org/10.3390/met10111483.

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An industrial press was used to consolidate compacted aluminum powder with a nominal diameter in the range of 1 µm. Direct and indirect hot-extrusion processes were used, and suitable process parameters were determined from heating conditions, ram speeds and billet temperatures. For comparison, a direct-extrusion press for hot extrusion of a conventional aluminum alloy AA 1050 was used. The extruded Al powder showed better mechanical properties and showed a thermal stability of the mechanical properties after annealing treatments. To increase the theoretical density of the directly extruded Al
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12

Chandekar, Anish, Dinesh K. Mishra, Sanjay Sharma, Gaurav K. Saraogi, Umesh Gupta, and Gaurav Gupta. "3D Printing Technology: A New Milestone in the Development of Pharmaceuticals." Current Pharmaceutical Design 25, no. 9 (2019): 937–45. http://dx.doi.org/10.2174/1381612825666190507115504.

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The global market of pharmaceuticals has witnessed a new revolution recently in the form of threedimensional printing (3D) technology. 3D printing has its existence since the 1980s that uses a 3D printer to manufacture the different dosage forms through computer-aided drug design technology. The need for 3D printing is due to numerous advantages like personalized medicine, tailored doses, rapid disintegration in case of SLS technique, incorporation of high doses and taste masking capacity. The different techniques used in 3D printing are Powder based (PB), Semi-solid extrusion (EXT), Fused dep
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13

Azouzi, Meher, Eric Labbe, Vincent Marquet, Raphael Moulart, and Samir Allaoui. "X-ray Tomography Investigation of the Quality of Architected Structures Obtained with Additive Manufacturing Processes." Journal of Manufacturing and Materials Processing 6, no. 4 (2022): 73. http://dx.doi.org/10.3390/jmmp6040073.

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Additive Manufacturing (AM) appears to be the best candidate to manufacture random architected materials, as it offers significant freedom in the design of hollowed parts with complex geometry. However, when these structures are needed with thins walls and struts, AM processes may encounter difficulties in properly manufacturing these structures due to their capability limits. This study proposes to characterize the manufacturing of random architected structures to see firstly their fabricability and the capability of the additive manufacturing processes used, such as vat photopolymerization (
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14

Couvrat, Mathieu, Laurent Chaffron, Daniel Nunes, Patrick Bonnaillie, Marie Hélène Mathon, and Mikael Perrut. "Microstructure Evolution of Mechanically Alloyed ODS Ferritic Steels during Hot Extrusion." Solid State Phenomena 172-174 (June 2011): 721–26. http://dx.doi.org/10.4028/www.scientific.net/ssp.172-174.721.

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Direct hot extrusion of powder is the standard consolidation process to transform mechanically alloyed Oxide Dispersion Strengthened (ODS) steels into fully dense bars. It is a complex process including several steps. In this study, ODS steel bars were extruded and the material microstructure was characterized by TEM observations associated to SANS after each step. It was shown that the nano-cluster nucleation occurs during the powder pre-heating before hot-extrusion. During extrusion, the ferritic matrix undergoes a dynamic recovery but no further change of the nano-cluster distribution is ob
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15

Nguyen, Thuyet Minh, Viet Hoang Nguyen, and Jin-Chun Kim. "The Microstructural Revolution of Ti-6Al-4V Specimens Fabricated by Selective Laser Sintering of Pre-alloyed Powders." Vietnam Journal of Science and Technology 57, no. 3A (2019): 103. http://dx.doi.org/10.15625/2525-2518/57/3a/13941.

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Selective laser sintering (SLS) is known as a cutting-edge technique to manufacture complex geometry products. Among various kinds of materials, Ti-6Al-4V is one of the most popular materials for the SLS process. The as-built Ti-6Al-4V products were widely applied in many applications such as aerospace, automobile, and especially in medical and implant parts. The purpose of this research is to investigate the microstructure and other properties of Ti6Al4V pre-alloyed powders produced by selective laser sintering technique. Through this research, the direct fabrication of Ti6Al4V metal object b
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16

Mierzejewska, Ż. A. "Process Optimization Variables for Direct Metal Laser Sintering." Advances in Materials Science 15, no. 4 (2015): 38–51. http://dx.doi.org/10.1515/adms-2015-0021.

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AbstractManufacturing is crucial to creation of wealth and provision of quality of life. Manufacturing covers numerous aspects from systems design and organization, technology and logistics, operational planning and control. The study of manufacturing technology is usually classified into conventional and non-conventional processes. As it is well known, the term "rapid prototyping" refers to a number of different but related technologies that can be used for building very complex physical models and prototype parts directly from 3D CAD model. Among these technologies are selective laser sinter
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17

Senkov, O. N., S. V. Senkova, J. M. Scott, and D. B. Miracle. "Compaction of amorphous aluminum alloy powder by direct extrusion and equal channel angular extrusion." Materials Science and Engineering: A 393, no. 1-2 (2005): 12–21. http://dx.doi.org/10.1016/j.msea.2004.09.061.

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18

Li, Zhong, Xiao Gang Hu, Hong Xing Lu, and Qiang Zhu. "Microstructure Design of Semi-Solid Slurry for Metal Direct Writing." Solid State Phenomena 348 (August 28, 2023): 33–38. http://dx.doi.org/10.4028/p-qdk1x5.

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Metal direct writing in semi-solid slurry is an innovative technology to realize low-cost printing of load-bearing parts in contrast to laser-based additive manufacturing. However, it is challenging to achieve near net-forming of 3D parts in the current stage because of the out of controlled microstructure and hence the unstable macro extrusion of the used semi-solid slurry. Here, mixed powder remelting (MPR) is introduced to actively design the characteristics of solid phases, i.e., solid fraction, shape factor, and size distribution. Specifically, high-melting-point pure Al powder served as
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19

Cerejo, Fábio, Daniel Gatões, and M. T. Vieira. "Optimization of metallic powder filaments for additive manufacturing extrusion (MEX)." International Journal of Advanced Manufacturing Technology 115, no. 7-8 (2021): 2449–64. http://dx.doi.org/10.1007/s00170-021-07043-0.

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AbstractAdditive manufacturing (AM) of metallic powder particles has been establishing itself as sustainable, whatever the technology selected. Material extrusion (MEX) integrates the ongoing effort to improve AM sustainability, in which low-cost equipment is associated with a decrease of powder waste during manufacturing. MEX has been gaining increasing interest for building 3D functional/structural metallic parts because it incorporates the consolidated knowledge from powder injection moulding/extrusion feedstocks into the AM scope—filament extrusion layer-by-layer. Moreover, MEX as an indir
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20

Tuazon, Brian J., and John Ryan Cortez Dizon. "Additive Manufacturing Technology in the Furniture Industry: Future Outlook for Developing Countries." Advance Sustainable Science Engineering and Technology 6, no. 3 (2024): 02403024. http://dx.doi.org/10.26877/asset.v6i3.908.

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For the past few years, the adoption of 3D printing technology has benefited various manufacturing industries, including the furniture making industry. However, this adoption has been greatly seen in industrialized countries and lacking in developing countries. Therefore, to understand fully the capability of 3D printing and its benefits, this paper review discusses recent applications of 3D printing in the furniture industry and assesses the potential it can bring for developing countries’ furniture making industry, specifically in the Philippines and other developing countries in Asia. In ad
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21

Shivam, Sachan, and Kumar Singh Yadav Sanjeev. "Comparative Study of Tensile Properties of 17-4PH Using ADAM and Conventional Process." International Journal of Research in Aeronautical and Mechanical Engineering 10, no. 8 (2022): 1–10. https://doi.org/10.5281/zenodo.6958661.

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This present work aims to compare the Tensile properties of 17-4PH stainless steel with two different processes. The first is the ADAM Atomic Diffusion Additive Manufacturing process, and the second process is making a sample for 17-4PH with a metal plate. Markforged ADAM is a patented process for Additive Manufacturing Process Metal Extrusion by Markforged. In this process, the 17-4PH metal powder is converted into a wire filament, and the filament is prepared with metal powder encased in a plastic binder. The ADAM process consists of three processes. 1. Printing, 2. Washing 3. Sintering. In
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Yang, Fei, Brian Gabbitas, Stiliana Raynova, Ajit Pal Singh, and Leandro Bolzoni. "Preparation of Ti-5553 Alloy by Different Extrusion Processes from Elemental Powder Mixtures." Key Engineering Materials 770 (May 2018): 31–38. http://dx.doi.org/10.4028/www.scientific.net/kem.770.31.

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Ti-5553 (Ti-5Al-5V-5Mo-3Cr, wt. %) alloy is a recently developed near β titanium alloy and it has a very good hardenability, good ductility and high strength. In this study, we discussed the feasibility of preparing Ti-5553 alloy by different processes from powder mixtures of hydride-dehydride titanium powder, elemental powders and master alloy powders, including (1) direct extrusion of powder compact in argon, (2) extrusion of the vacuum-sintered billet in air and (3) extrusion of the hot-pressed billet in air. XRD, OM and SEM were used to determine the phase constitutions and microstructures
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Wang, Zhi, Bing Xu, Jiawei Yuan, et al. "Study on Preparation and Forming of TiC Steel-Bonded Cemented Carbide Paste for Direct Writing Printing." Journal of Electronic Research and Application 9, no. 2 (2025): 216–25. https://doi.org/10.26689/jera.v9i2.10156.

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TiC steel-bound cemented carbide body was prepared by direct writing printing. The effects of powder content (89.28, 89.49, 89.69, 89.88, and 90.07 wt%) and dispersant content (0.017, 0.034, 0.051, and 0.068 wt%) on the slurry and printing body were studied. The experimental results show that with the increase of powder content, the viscosity of the slurry gradually increases, the settlement rate gradually decreases, and the size and linewidth of the blank body gradually decreases. When the powder content is 89.69 wt%, the sedimentation stability and extrusion stability of the slurry are the b
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Bai, Qian, Jian Guo Lin, Gao Feng Tian, Daniel S. Balint, and Jin Wen Zou. "A Novel Forming Process for Powder Metallurgy of Superalloys." Key Engineering Materials 622-623 (September 2014): 833–39. http://dx.doi.org/10.4028/www.scientific.net/kem.622-623.833.

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Powder metallurgy (PM) of nickel-based superalloys has been used for a wide range of products owing to their excellent special properties in processing and applications. Typical processes for high performance PM superalloys include hot isostatic pressing, hot extrusion and hot isothermal forging. Hot isostatic pressing is normally conducted at a high temperature, by using a low pressure for a long time in a closed vessel, resulting in high cost and low product efficiency. In this paper a novel forming process, i.e. direct powder forging for powder metallurgy of superalloys has been proposed. I
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Stel'makh, Lyubov' S., Alexandra O. Zhidovich, Alexander M. Stolin, and Sergey V. Karpov. "Finding rational regimes for direct fabrication of long products from powders of refractory compounds by SHS extrusion." Image Journal of Advanced Materials and Technologies 7, no. 3 (2022): 172–80. http://dx.doi.org/10.17277/jamt.2022.03.pp.172-180.

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Lupo, Marco, Diego Barletta, Daniele Sofia, and Massimo Poletto. "Calibration of DEM for Cohesive Particles in the SLS Powder Spreading Process." Processes 9, no. 10 (2021): 1715. http://dx.doi.org/10.3390/pr9101715.

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In this paper, a new DEM calibration procedure based on two different types of procedures to compare simulation with experiments is proposed. The aim is to find the values of the interfacial adhesive surface energy and the coefficient of rolling friction between the particles to be used in the simulation. The approach adopted is the so-called Bulk Calibration method. The experimental values of the angle of repose and unconfined yield strength, found with a static testing method and by shear testing, respectively, are compared, respectively, with the angle of repose, found in a simulation repro
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Zubizarreta, C., S. Giménez, J. M. Martín, and I. Iturriza. "Effect of the heat treatment prior to extrusion on the direct hot-extrusion of aluminium powder compacts." Journal of Alloys and Compounds 467, no. 1-2 (2009): 191–201. http://dx.doi.org/10.1016/j.jallcom.2007.12.035.

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Tateno, Toshitake, Akira Kakuta, Hayate Ogo, and Takaya Kimoto. "Ultrasonic Vibration-Assisted Extrusion of Metal Powder Suspension for Additive Manufacturing." International Journal of Automation Technology 12, no. 5 (2018): 775–83. http://dx.doi.org/10.20965/ijat.2018.p0775.

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Additive manufacturing (AM) using metal materials can be used to manufacture metal parts with complex shapes that are difficult to manufacture with subtractive processing. Recently, numerous commercial AM machines for metallic materials have been developed. The primary types of AM using metallic materials are powder bed fusion or direct energy deposition. Other types using metallic materials have not been adequately studied. In this study, the use of the material extrusion (ME) type of AM is investigated. The aim is to use metallic materials not only for fabricating metal parts but also for ad
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Płonka, Bartłomiej, and Juliusz Senderski. "Advanced Technologies Used in the Manufacture of Products from Aluminium Alloys Powder in Extrusion Process." Key Engineering Materials 491 (September 2011): 59–66. http://dx.doi.org/10.4028/www.scientific.net/kem.491.59.

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The subject of the research was an alloy AlZnMg and AlCuMg with addition of Zr and Ag manufactured of powders by hot plastic consolidation in process of direct extrusion. Paper also presents results of research of structure evolution and mechanical properties for different tempers of precipitation strengthening and further plastic deformation, including hydrostatic extrusion. Obtained results Rm above 700MPa (for AlZnMg alloy) and above 500MPa (for AlCuMg alloy) shows significant possibilities of manufacturing from Al alloys powders products with ultrafine grain and nanometric structure which
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Chadha, Utkarsh, Senthil Kumaran Selvaraj, Abel Saji Abraham, et al. "Powder Bed Fusion via Machine Learning-Enabled Approaches." Complexity 2023 (April 30, 2023): 1–25. http://dx.doi.org/10.1155/2023/9481790.

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Powder bed fusion (PBF) applies to various metallic materials used in the metal printing process of building a wide range of complex parts compared to other AM technologies. PBF process has several variants such as DMLS (direct metal laser sintering), EBM (electron beam melting), SHS (selective heat sintering), SLM (selective laser melting), and SLS (selective laser sintering). For PBF to reach its maximum potential, machine learning (ML) algorithms are used with suitable materials to achieve goals cost-effectively. Various applications of neural networks, including ANNs, CNNs, RNNs, and other
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Singh, Daler, and Sukhjinder Singh Sandhu. "Effect of Laser Power on Component Strength in Laser Sintering." International Journal of Advance Research and Innovation 4, no. 1 (2016): 162–67. http://dx.doi.org/10.51976/ijari.411625.

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Prototyping or model making is one of the important steps to finalize a product design. It helps in conceptualization of a design. Before the start of full production a prototype is usually fabricated and tested. RP processes namely Stereo-lithography (SL), Selective Laser Sintering (SLS), Fused Deposition Modeling (FDM) and Laminated Object Manufacturing (LOM) are described. In Selective Laser Sintering (SLS) process, fine polymeric powder like polystyrene, polycarbonate or polyamide etc. (20 to 100 micrometer diameter) is spread on the substrate using a roller. Before starting CO2 laser scan
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Guo, Zhi Qiang, Xiang Li, Xiao Guang Yuan, and Hong Jun Huang. "Effects of Extrusion Methods and Powder Carriers on Powder Forming and Precursor Foaming Behavior in the Preparation Process of Aluminum Foam." Advanced Materials Research 634-638 (January 2013): 1734–39. http://dx.doi.org/10.4028/www.scientific.net/amr.634-638.1734.

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Aluminum foam is a new type of material that can be used in many fields. Compaction conditions are the most important parameters that have influence on foam preparation process. So in this paper, detailed researches about extrusion methods and powder carriers are conducted. The results show that: compare with direct extrusion, pre-pressing can effectively eliminate the influences of hydrogen, obtain high density precursors. However, when the flank of the precursor is wrapped with copper, H2 can escape from the combination parts of Al and Cu, in early foaming stage. The minimum density is only
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Min, Wang Kee, Chang Ho Lee, Yong Ho Park, and Ik Min Park. "Influence of Extrusion Temperature on the Thermoelectric Properties of p-Type Ag Added (Bi0.25Sb0.75)2Te3 Alloys Prepared by MA-PDS." Key Engineering Materials 336-338 (April 2007): 846–49. http://dx.doi.org/10.4028/www.scientific.net/kem.336-338.846.

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The direct extrusion process using the powder as raw materials was applied to prepare the thermoelectric materials. The mechanically alloyed powders of Ag added (Bi0.25Sb0.75)2Te3 were extruded by pulse discharge sintering method in the temperature range of 345°C ~ 425°C. High quality products were obtained by hot-extrusion method and their texture and thermoelectric properties were measured. The intensity of (110) plane increased with extrusion temperature up to 385°C and altered in the range of above 405°Cwhich coincided with the variation of power factor. The measured Power factor ranged fr
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Min, Wang Kee, Sung Doo Hwang, Chang Ho Lee, Young Do Park, Yong Ho Park, and Ik Min Park. "Influence of Thermo-Mechanical Heat Treatment on the Thermoelectric Properties of Ag Added Bi1Sb3Te6 Compounds." Solid State Phenomena 118 (December 2006): 47–52. http://dx.doi.org/10.4028/www.scientific.net/ssp.118.47.

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The direct extrusion process using the mechanically alloyed powder as raw materials was applied to prepare the thermoelectric materials. The mechanically alloyed powders of Ag added Bi1Sb3Te6 were extruded using pulse discharge sintering method at temperatures ranging from 345°C to 425°C. The fractographs of extruded specimens shows that no grain size changes was observed until 385°C, but became coarser with the increase of the extrusion temperature above 405°C. The X-ray diffraction patterns showed that the intensity of (110) plane increased with extrusion temperature up to 385°C and started
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Fratini, Costanza, Sofia Moroni, Davide De Angelis, et al. "Direct powder extrusion (DPE) 3D-printing of mini-tablets for preclinical studies in rodents." International Journal of Pharmaceutics 675 (April 2025): 125542. https://doi.org/10.1016/j.ijpharm.2025.125542.

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Bhavesh, Machhi* Aathira Chandran Divyanka Bodas Chandrakant Wadile Pankaj Mandpe. "Recent Advancement: 3D-Printed Orodispersible Film as Pharmaceutical Dosage Forms for Paediatric Patients." International Journal of Pharmaceutical Sciences 3, no. 1 (2025): 1324–38. https://doi.org/10.5281/zenodo.14673092.

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Traditional drug delivery systems are often unsuitable for paediatric patients due to their unique developmental stages and specific dosing requirements are distinct from those of other groups within the population. Oral delivery is recognized as the most user-friendly and popular method in therapeutic practices due to its safety, high patient compliance, ease of administration, affordable price, and flexibility. The challenge of medication adherence is increasingly recognized as a critical public health issue, with poor adherence to treatment linked to negative health consequences and higher
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Aguilar-de-Leyva, Ángela, Marta Casas, Carmen Ferrero, Vicente Linares, and Isidoro Caraballo. "3D Printing Direct Powder Extrusion in the Production of Drug Delivery Systems: State of the Art and Future Perspectives." Pharmaceutics 16, no. 4 (2024): 437. http://dx.doi.org/10.3390/pharmaceutics16040437.

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The production of tailored, on-demand drug delivery systems has gained attention in pharmaceutical development over the last few years, thanks to the application of 3D printing technology in the pharmaceutical field. Recently, direct powder extrusion (DPE) has emerged among the extrusion-based additive manufacturing techniques. It is a one-step procedure that allows the direct processing of powdered formulations. The aim of this systematic literature review is to analyze the production of drug delivery systems using DPE. A total of 27 articles have been identified through scientific databases
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Kamboj, Nikhil, Antonia Ressler, and Irina Hussainova. "Bioactive Ceramic Scaffolds for Bone Tissue Engineering by Powder Bed Selective Laser Processing: A Review." Materials 14, no. 18 (2021): 5338. http://dx.doi.org/10.3390/ma14185338.

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The implementation of a powder bed selective laser processing (PBSLP) technique for bioactive ceramics, including selective laser sintering and melting (SLM/SLS), a laser powder bed fusion (L-PBF) approach is far more challenging when compared to its metallic and polymeric counterparts for the fabrication of biomedical materials. Direct PBSLP can offer binder-free fabrication of bioactive scaffolds without involving postprocessing techniques. This review explicitly focuses on the PBSLP technique for bioactive ceramics and encompasses a detailed overview of the PBSLP process and the general req
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39

Mikhailov, A., Ye Shtefan, and O. Mikhailov. "Modeling of manufacturing processes of thin-walled bushings from porous blanks using direct extrusion and radial compaction." Uspihi materialoznavstva 2023, no. 7 (2023): 19–26. http://dx.doi.org/10.15407/materials2023.07.002.

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The deformation process of powder materials thin-walled bushings manufacture was investigated by computer modeling. Two shape formation bushings schemeswere considered (direct extrusion and radial compaction).A continuum approach was used to create a modeling method. The method is based on rheological models of porous body plastic deformation and the finite element method. The accepted material rheological model allows describing the deformation of both powder and porous blanks. It takes into account the different resistance of these materials in tension and compression. Modeling of the deform
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40

Santos, Cyril, Daniel Gatões, Fábio Cerejo, and Maria Teresa Vieira. "Influence of Metallic Powder Characteristics on Extruded Feedstock Performance for Indirect Additive Manufacturing." Materials 14, no. 23 (2021): 7136. http://dx.doi.org/10.3390/ma14237136.

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Material extrusion (MEX) of metallic powder-based filaments has shown great potential as an additive manufacturing (AM) technology. MEX provides an easy solution as an alternative to direct additive manufacturing technologies (e.g., Selective Laser Melting, Electron Beam Melting, Direct Energy Deposition) for problematic metallic powders such as copper, essential due to its reflectivity and thermal conductivity. MEX, an indirect AM technology, consists of five steps—optimisation of mixing of metal powder, binder, and additives (feedstock); filament production; shaping from strands; debinding;
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41

Xu, Jie, Yifan Fei, Yuanzhe Zhu, Wei Yu, Donggang Yao, and Jack G. Zhou. "A Review of Non-Powder-Bed Metal Additive Manufacturing: Techniques and Challenges." Materials 17, no. 19 (2024): 4717. http://dx.doi.org/10.3390/ma17194717.

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Metal additive manufacturing has significantly evolved since the 1990s, achieving a market valuation of USD 6.36 billion in 2022, with an anticipated compound annual growth rate of 24.2% from 2023 to 2030. While powder-bed-based methods like powder bed fusion and binder jetting dominate the market due to their high accuracy and resolution, they face challenges such as lengthy build times, excessive costs, and safety concerns. Non-powder-bed-based techniques, including direct energy deposition, material extrusion, and sheet lamination, offer advantages such as larger build sizes and lower energ
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42

Rodríguez-González, Paula, Elisa María Ruiz-Navas, and Elena Gordo. "Effect of Heat Treatment Prior to Direct Hot-Extrusion Processing of Al–Cu–Li Alloy." Metals 12, no. 6 (2022): 1046. http://dx.doi.org/10.3390/met12061046.

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This study presents and explains the results of the first steps in developing high strength aluminium alloy (Al–Cu–Li) wires for the ultimate purpose of using them as feedstock for DED (directed energy deposition) techniques, such as wire arc additive manufacturing (WAAM). Powder metallurgy (PM) is proposed as the method to produce the wires due to the high flexibility to adapt the composition and the lower temperatures used with respect to casting. Two PM routes are proposed. The first route comprises blending of the powders, uniaxial pressing, and hot extrusion of the green compact to obtain
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43

Ueda, Jun, David B. Comber, Jonathon Slightam, et al. "MRI–Compatible Fluid-Powered Medical Devices." Mechanical Engineering 135, no. 06 (2013): S13—S16. http://dx.doi.org/10.1115/1.2013-jun-8.

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This article introduces recent developments and challenges related to magnetic resonance imaging (MRI)-compatible medical devices. Recent advances in fluid-powered medical devices are described, including a needle steering robot for neurosurgery and a haptic device for hemiplegia rehabilitation. Recent three-dimensional printing technologies for fabricating integrated fluid-powered robots are also reported. The use of additive manufacturing conjoined with modern digital imaging techniques allow for the customization of components, a trait that is generally needed in medical implants and device
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Goyanes, Alvaro, Nour Allahham, Sarah J. Trenfield, Edmont Stoyanov, Simon Gaisford, and Abdul W. Basit. "Direct powder extrusion 3D printing: Fabrication of drug products using a novel single-step process." International Journal of Pharmaceutics 567 (August 2019): 118471. http://dx.doi.org/10.1016/j.ijpharm.2019.118471.

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45

Wen, Xuemei, Zhaoyou Deng, Yangfeng Xu, et al. "Preparation and In Vitro/In Vivo Evaluation of Orally Disintegrating/Modified-Release Praziquantel Tablets." Pharmaceutics 13, no. 10 (2021): 1567. http://dx.doi.org/10.3390/pharmaceutics13101567.

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This study was designed to develop orally disintegrating/sustained-release praziquantel (PZQ) tablets using the hot-melt extrusion (HME) technique and direct compression, and subsequently evaluate their release in in vitro and in vivo pharmacokinetics. For the extrusion process, hypromellose acetate succinate (HPMCAS)-LG was the carrier of pure PZQ, with a standard screw configuration used at an extrusion temperature of 140 °C and a screw rotation speed of 100 rpm. Differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), powder X-ray diffraction (PXRD) and Fourier-transform i
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46

Sánchez-Guirales, Sergio A., Noelia Jurado, Aytug Kara, Aikaterini Lalatsa, and Dolores R. Serrano. "Understanding Direct Powder Extrusion for Fabrication of 3D Printed Personalised Medicines: A Case Study for Nifedipine Minitablets." Pharmaceutics 13, no. 10 (2021): 1583. http://dx.doi.org/10.3390/pharmaceutics13101583.

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Fuse deposition modelling (FDM) has emerged as a novel technology for manufacturing 3D printed medicines. However, it is a two-step process requiring the fabrication of filaments using a hot melt extruder with suitable properties prior to printing taking place, which can be a rate-limiting step in its application into clinical practice. Direct powder extrusion can overcome the difficulties encountered with fabrication of pharmaceutical-quality filaments for FDM, allowing the manufacturing, in a single step, of 3D printed solid dosage forms. In this study, we demonstrate the manufacturing of sm
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47

Zaid, Mohd, Khamirul Matori, Aziz Ab, Zaidan Wahab, and Siti Rashid. "Effect of sintering on crystallization and structural properties of soda lime silica glass." Science of Sintering 49, no. 4 (2017): 409–17. http://dx.doi.org/10.2298/sos1704409z.

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The effect of sintering temperatures on crystallization and structural of the soda lime silica (SLS) glass was reported. Elemental weight composition of the SLS glass powder was identified through Energy dispersive X-ray fluorescence (EDXRF) analysis while the thermal behavior of the glass was determined using Differential thermal analysis (DTA) technique. Archimedes? method and direct geometric measurement were respectively used to determine bulk density and linear shrinkage of the glass samples. Crystallisation behavior of the samples was investigated by X-ray diffraction (XRD) analysis and
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48

Singhal, Peeush. "OPTIMIZED FAST DISINTEGRATING TABLETS, BOOSTED OSELTAMIVIR PHOSPHATE ORALLY FAST DISINTEGRATING TABLETS." Journal of Medical pharmaceutical and allied sciences 10, no. 6 (2021): 3781–88. http://dx.doi.org/10.22270/jmpas.v10i6.1479.

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Background Around 33% of the populace (fundamentally pediatric and geriatric) has gulping hardships, bringing about helpless consistence with oral tablet drug treatment which prompts decreased in general treatment viability. For this explanation, tablets that can quickly break down or deteriorate in the oral cavity have drawn in a lot of consideration. Objective research was designed to develop and evaluate boosted orally fast disintegrating tablets (OFDT) for oro-buccal drug delivery of oseltamivir phosphate. Methods In the present study six formulations of mouth dissolving tablet of oseltami
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Mendibil, Xabier, Gaizka Tena, Alaine Duque, Nerea Uranga, Miguel Ángel Campanero, and Jesús Alonso. "Direct Powder Extrusion of Paracetamol Loaded Mixtures for 3D Printed Pharmaceutics for Personalized Medicine via Low Temperature Thermal Processing." Pharmaceutics 13, no. 6 (2021): 907. http://dx.doi.org/10.3390/pharmaceutics13060907.

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Three-dimensional printed drug development is nowadays an active area in the pharmaceutical industry, where the search for an appropriate edible carrier that permits the thermal processing of the mixture at temperature levels that are safe for the drug is an important field of study. Here, potato starch and hydroxypropyl cellulose based mixtures loaded with paracetamol up to 50% in weight were processed by hot melt extrusion at 85 °C to test their suitability to be thermally processed. The extruded mixtures were tested by liquid chromatography to analyze their release curves and were thermally
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50

Zhang, Rui Shi, J. Z. Pan, and L. W. Wang. "Manufacture of Fine AL2O3 Granules as Catalyst Carrier by an Extrusion/Spheronization Method." Advanced Materials Research 44-46 (June 2008): 361–66. http://dx.doi.org/10.4028/www.scientific.net/amr.44-46.361.

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The effect of formulation (filler’s kind and amount, liquid’s kind and concentration required for granulation) and spheronization time on characterization of alumina based pellets parameters (pellets size distribution, roundness and aspect ratio) were investigated. Two schemes were successfully proofed by extrusion/spheronization. The mean volume particle diameter was found to have a profound effect on the formulation and processing parameters. Alumina powder with large mean volume particle diameter showed different mechanism of action with coupling agent. With the surface modification, the wa
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