Relevant bibliographies by topics / Small Untranslated RNA

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Academic literature on the topic 'Small Untranslated RNA'

Author: Grafiati
Published: 4 June 2021
Last updated: 29 January 2023

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Journal articles on the topic "Small Untranslated RNA"

1

Silvaggi, Jessica M., John B. Perkins, and Richard Losick. "Small Untranslated RNA Antitoxin in Bacillus subtilis." Journal of Bacteriology 187, no. 19 (2005): 6641–50. http://dx.doi.org/10.1128/jb.187.19.6641-6650.2005.

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ABSTRACT Toxin-antitoxin (TA) modules are pairs of genes in which one member encodes a toxin that is neutralized or whose synthesis is prevented by the action of the product of the second gene, an antitoxin, which is either protein or RNA. We now report the identification of a TA module in the chromosome of Bacillus subtilis in which the antitoxin is an antisense RNA. The antitoxin, which is called RatA (for RNA antitoxin A), is a small (222 nucleotides), untranslated RNA that blocks the accumulation of the mRNA for a toxic peptide TxpA (for toxic peptide A; formerly YqdB). The txpA and ratA g
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2

Skryabin, Boris V., Valentina Sukonina, Ursula Jordan, et al. "Neuronal Untranslated BC1 RNA: Targeted Gene Elimination in Mice." Molecular and Cellular Biology 23, no. 18 (2003): 6435–41. http://dx.doi.org/10.1128/mcb.23.18.6435-6441.2003.

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ABSTRACT Despite the potentially important roles of untranslated RNAs in cellular form or function, genes encoding such RNAs have until now received surprisingly little attention. One such gene encodes BC1 RNA, a small non-mRNA that is delivered to dendritic microdomains in neurons. We have now eliminated the BC1 RNA gene in mice. Three independent founder lines were established from separate embryonic stem cells. The mutant mice appeared to be healthy and showed no anatomical or neurological abnormalities. The gross brain morphology was unaltered in such mice, as were the subcellular distribu
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Macdonald, P. M., K. Kerr, J. L. Smith, and A. Leask. "RNA regulatory element BLE1 directs the early steps of bicoid mRNA localization." Development 118, no. 4 (1993): 1233–43. http://dx.doi.org/10.1242/dev.118.4.1233.

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Deployment of the bicoid morphogen gradient in early Drosophila embryos requires the prelocalization of bicoid mRNA to the anterior pole of the egg. This anterior localization is mediated by a cis-acting localization signal contained within the 3′ untranslated region of the bicoid mRNA. Here we use a series of bicoid transgenes carrying small deletions in the 3′ untranslated region to survey for functional elements that constitute the localization signal. We identify and characterize one essential element, BLE1, which specifically directs the early steps of localization. In addition, we find t
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Hartmann, Claudia, Corinna Benz, Stefanie Brems, et al. "Small Trypanosome RNA-Binding Proteins TbUBP1 and TbUBP2 Influence Expression of F-Box Protein mRNAs in Bloodstream Trypanosomes." Eukaryotic Cell 6, no. 11 (2007): 1964–78. http://dx.doi.org/10.1128/ec.00279-07.

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ABSTRACT In the African trypanosome Trypanosoma brucei nearly all control of gene expression is posttranscriptional; sequences in the 3′-untranslated regions of mRNAs determine the steady-state mRNA levels by regulation of RNA turnover. Here we investigate the roles of two related proteins, TbUBP1 and TbUBP2, containing a single RNA recognition motif, in trypanosome gene expression. TbUBP1 and TbUBP2 are in the cytoplasm and nucleus, comprise ca. 0.1% of the total protein, and are not associated with polysomes or RNA degradation enzymes. Overexpression of TbUBP2 upregulated the levels of sever
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Davis, Brigid M., Mariam Quinones, Jason Pratt, Yanpeng Ding, and Matthew K. Waldor. "Characterization of the Small Untranslated RNA RyhB and Its Regulon in Vibrio cholerae." Journal of Bacteriology 187, no. 12 (2005): 4005–14. http://dx.doi.org/10.1128/jb.187.12.4005-4014.2005.

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ABSTRACT Numerous small untranslated RNAs (sRNAs) have been identified in Escherichia coli in recent years, and their roles are gradually being defined. However, few of these sRNAs appear to be conserved in Vibrio cholerae, and both identification and characterization of sRNAs in V. cholerae remain at a preliminary stage. We have characterized one of the few sRNAs conserved between E. coli and V. cholerae: RyhB. Sequence conservation is limited to the central region of the gene, and RyhB in V. cholerae is significantly larger than in E. coli. As in E. coli, V. cholerae RyhB is regulated by the
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6

Higgs, David C., Risa S. Shapiro, Karen L. Kindle, and David B. Stern. "Small cis-Acting Sequences That Specify Secondary Structures in a Chloroplast mRNA Are Essential for RNA Stability and Translation." Molecular and Cellular Biology 19, no. 12 (1999): 8479–91. http://dx.doi.org/10.1128/mcb.19.12.8479.

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ABSTRACT Nucleus-encoded proteins interact with cis-acting elements in chloroplast transcripts to promote RNA stability and translation. We have analyzed the structure and function of three such elements within the Chlamydomonas petD 5′ untranslated region; petD encodes subunit IV of the cytochromeb 6/f complex. These elements were delineated by linker-scanning mutagenesis, and RNA secondary structures were investigated by mapping nuclease-sensitive sites in vitro and by in vivo dimethyl sulfate RNA modification. Element I spans a maximum of 8 nucleotides (nt) at the 5′ end of the mRNA; it is
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7

Shirokikh, Nikolay E., Yulia S. Dutikova, Maria A. Staroverova, Ross D. Hannan, and Thomas Preiss. "Migration of Small Ribosomal Subunits on the 5′ Untranslated Regions of Capped Messenger RNA." International Journal of Molecular Sciences 20, no. 18 (2019): 4464. http://dx.doi.org/10.3390/ijms20184464.

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Several control mechanisms of eukaryotic gene expression target the initiation step of mRNA translation. The canonical translation initiation pathway begins with cap-dependent attachment of the small ribosomal subunit (SSU) to the messenger ribonucleic acid (mRNA) followed by an energy-dependent, sequential ‘scanning’ of the 5′ untranslated regions (UTRs). Scanning through the 5′UTR requires the adenosine triphosphate (ATP)-dependent RNA helicase eukaryotic initiation factor (eIF) 4A and its efficiency contributes to the specific rate of protein synthesis. Thus, understanding the molecular det
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8

Waldminghaus, Torsten, Anja Fippinger, Juliane Alfsmann та Franz Narberhaus. "RNA thermometers are common in α- and γ-proteobacteria". Biological Chemistry 386, № 12 (2005): 1279–86. http://dx.doi.org/10.1515/bc.2005.145.

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AbstractExpression of many rhizobial small heat-shock genes is controlled by the ROSE element, a thermoresponsive structure in the 5′-untranslated region of the corresponding mRNAs. Using a bioinformatics approach, we found more than 20 new potential ROSE-like RNA thermometers upstream of small heat-shock genes in a wide variety of α- and γ-proteobacteria. Northern blot analyses revealed heat-inducible transcripts of the representative candidateCaulobacter crescentus CC2258,Escherichia coli ibpAandSalmonella typhimurium ibpAgenes. Typical σ32-type promoters were mapped upstream of the potentia
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9

Kunden, Rasika D., Sarah Ghezelbash, Juveriya Q. Khan, and Joyce A. Wilson. "Location specific annealing of miR-122 and other small RNAs defines an Hepatitis C Virus 5′ UTR regulatory element with distinct impacts on virus translation and genome stability." Nucleic Acids Research 48, no. 16 (2020): 9235–49. http://dx.doi.org/10.1093/nar/gkaa664.

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Abstract Hepatitis C virus (HCV) replication requires annealing of a liver specific small-RNA, miR-122 to 2 sites on 5′ untranslated region (UTR). Annealing has been reported to (a) stabilize the genome, (b) stimulate translation and (c) promote the formation of translationally active Internal Ribosome Entry Site (IRES) RNA structure. In this report, we map the RNA element to which small RNA annealing promotes HCV to nucleotides 1–44 and identify the relative impact of small RNA annealing on virus translation promotion and genome stabilization. We mapped the optimal region on the HCV genome to
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10

Booy, Evan P., Ryan Howard, Oksana Marushchak, et al. "The RNA helicase RHAU (DHX36) suppresses expression of the transcription factor PITX1." Nucleic Acids Research 42, no. 5 (2013): 3346–61. http://dx.doi.org/10.1093/nar/gkt1340.

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Abstract RNA Helicase associated with AU-rich element (RHAU) (DHX36) is a DEAH (Aspartic acid, Glumatic Acid, Alanine, Histidine)-box RNA helicase that can bind and unwind G4-quadruplexes in DNA and RNA. To detect novel RNA targets of RHAU, we performed an RNA co-immunoprecipitation screen and identified the PITX1 messenger RNA (mRNA) as specifically and highly enriched. PITX1 is a homeobox transcription factor with roles in both development and cancer. Primary sequence analysis identified three probable quadruplexes within the 3′-untranslated region of the PITX1 mRNA. Each of these sequences,
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Dissertations / Theses on the topic "Small Untranslated RNA"

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Simkin, Alfred T. "Evolutionary Approaches to the Study of Small Noncoding Regulatory RNA Pathways: A Dissertation." eScholarship@UMMS, 2014. https://escholarship.umassmed.edu/gsbs_diss/721.

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Short noncoding RNAs play roles in regulating nearly every biological process, in nearly every organism, yet the exact function and importance of these molecules remains a subject of some debate. In order to gain a better understanding of the contexts in which these regulators have evolved, I have undertaken a variety of approaches to study the evolutionary history of the components that make up these pathways, in the form of two main research efforts. In the first chapter, I have used a combination of population genetics and molecular evolution techniques to show that proteins involved in the
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Simkin, Alfred T. "Evolutionary Approaches to the Study of Small Noncoding Regulatory RNA Pathways: A Dissertation." eScholarship@UMMS, 2007. http://escholarship.umassmed.edu/gsbs_diss/721.

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Short noncoding RNAs play roles in regulating nearly every biological process, in nearly every organism, yet the exact function and importance of these molecules remains a subject of some debate. In order to gain a better understanding of the contexts in which these regulators have evolved, I have undertaken a variety of approaches to study the evolutionary history of the components that make up these pathways, in the form of two main research efforts. In the first chapter, I have used a combination of population genetics and molecular evolution techniques to show that proteins involved in the
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3

Ghildiyal, Megha. "Endogenous Small RNAs in the Drosophila Soma: A Dissertation." eScholarship@UMMS, 2010. https://escholarship.umassmed.edu/gsbs_diss/459.

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Since the discovery in 1993 of the first small silencing RNA, a dizzying number of small RNAs have been identified, including microRNAs (miRNAs), small interfering RNAs (siRNAs) and Piwi-interacting RNAs (piRNAs). These classes differ in their biogenesis, modes of target regulation and in the biological pathways they regulate. Historically, siRNAs were believed to arise only from exogenous double-stranded RNA triggers in organisms lacking RNA-dependent RNA polymerases. However, the discovery of endogenous siRNAs in flies expanded the biological significance of siRNAs beyond viral defense. By h
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4

"Functional characterization of an exonic small non-coding RNA TIFm71." Thesis, 2011. http://library.cuhk.edu.hk/record=b6075396.

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Wang, Dakui.<br>Thesis (Ph.D.)--Chinese University of Hong Kong, 2011.<br>Includes bibliographical references (leaves 208-234).<br>Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web.<br>Abstract also in Chinese.
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5

Hsieh, Po Ting, and 謝柏廷. "Regulation of Enterovirus Viral Translation and RNA Replication: Role of Viral small RNA and 5' Untranslated Region." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/43cyca.

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6

chen, chun-chin, and 陳秋錦. "Functional analysis of the small RNA derived from the highly conserved 3’-untranslated region of Japanese encephalitis virus in infected mammalian cells." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/22361143479344785083.

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碩士<br>國立東華大學<br>生物技術研究所<br>93<br>英文摘要 Japanese encephalitis virus (JEV) contains a single positive-strand RNA genome of 10,976 nucleotides in length and is not formally thought to generate subgenomic RNA molecules during replication. Previous studies in our lab have reported the abundant accumulation of a 3’-terminal 521- to 523-nucleotide genome fragment, representing the highly conserved region of the 3’-untranslated region, in JEV-infected cells (Journal of Virology 78:5133, 2004). To address a possible function of the small RNA during viral replication, several approaches were carried out.
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Books on the topic "Small Untranslated RNA"

1

Rederstorff, Mathieu. Small non-coding RNAs: Methods and protocols. Humana Press, 2015.

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Rederstorff, Mathieu. Small Non-Coding RNAs: Methods and Protocols. Springer New York, 2016.

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Rederstorff, Mathieu. Small Non-Coding RNAs: Methods and Protocols. Springer, 2022.

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Rederstorff, Mathieu. Small Non-Coding RNAs: Methods and Protocols. Springer, 2021.

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