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Journal articles on the topic "Smg-8"

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Deniaud, Aurélien, Manikandan Karuppasamy, Thomas Bock, Simonas Masiulis, Karine Huard, Frédéric Garzoni, Kathrin Kerschgens, et al. "A network of SMG-8, SMG-9 and SMG-1 C-terminal insertion domain regulates UPF1 substrate recruitment and phosphorylation." Nucleic Acids Research 43, no. 15 (June 30, 2015): 7600–7611. http://dx.doi.org/10.1093/nar/gkv668.

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Pascall, J. C., J. Saunders, D. M. Blakeley, M. S. Laurie, and K. D. Brown. "Tissue-specific effects of castration and ovariectomy on murine epidermal growth factor and its mRNA." Journal of Endocrinology 121, no. 3 (June 1989): 501–6. http://dx.doi.org/10.1677/joe.0.1210501.

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ABSTRACT The polypeptide mitogen, epidermal growth factor (EGF), was originally isolated from mouse submaxillary gland (SMG). In mice, these glands are sexually dimorphic; the SMG of male animals typically contains up to 400 pmol EGF/mg protein whereas EGF concentrations in the SMG of female mice are only 5–20 pmol/mg protein. When mice were castrated at 8 weeks of age, EGF mRNA levels in the SMG fell rapidly to the low levels observed in control female animals. Although the concentration of EGF in the SMG, measured by radioimmunoassay, also fell to very low levels (13·8 ± 0·7 (s.e.m.) pmol/mg protein) in the castrated mice, the rate of decrease was considerably slower than that of the mRNA. In contrast to the loss of EGF and EGF mRNA from mice following castration, ovariectomy led to a rise in EGF mRNA levels in SMG, with a maximal increase (approximately 100-fold) 4–6 weeks after ovariectomy. Concentrations of EGF in the SMG also rose markedly in the ovariectomized animals, from a control value of 5·4 ± 0·8 to 34·7 ± 7·9 pmol/mg protein at 6 weeks. In mice, the kidney displays the second highest level of EGF gene expression. However, in contrast to the effects on SMG, kidney EGF mRNA was not affected by either castration or ovariectomy. These results provide further evidence for the tissue-specific control of EGF gene expression in response to steroid hormones. Journal of Endocrinology (1989) 121, 501–506
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Yamashita, A., N. Izumi, I. Kashima, T. Ohnishi, B. Saari, Y. Katsuhata, R. Muramatsu, et al. "SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay." Genes & Development 23, no. 9 (May 1, 2009): 1091–105. http://dx.doi.org/10.1101/gad.1767209.

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Williams, Grant Richard, Allison Mary Deal, Shlomit S. Shachar, Christine Marie Walko, Jai Narendra Patel, Bert H. O'Neil, Howard L. McLeod, et al. "The impact of sarcopenia on toxicity and pharmacokinetics of 5-fluorouracil (5FU) in colorectal cancer." Journal of Clinical Oncology 35, no. 4_suppl (February 1, 2017): 633. http://dx.doi.org/10.1200/jco.2017.35.4_suppl.633.

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633 Background: Great heterogeneity exists in the ability of adults with cancer to tolerate treatment. Variability in body composition may affect rates of metabolism of cytotoxic agents and contribute to the variable chemotherapy toxicity observed. The goal of this study was to explore the impact of body composition, in particular sarcopenia, on the pharmacokinetics of 5-fluorouracil (5FU) in a cohort of patients receiving FOLFOX +/- bevacizumab for colorectal cancer. Methods: We performed a secondary analysis of a completed multicenter trial that investigated pharmacokinetic-guided 5FU in patients receiving mFOLFOX6 +/- bevacizumab [Patel et al. The Oncologist 2014]. Computed Tomography (CT) images that were performed as part of routine care were used to for body composition analysis. Skeletal muscle area (SMA) and density (SMD) were analyzed from CT scan L3 lumbar segments using radiological software. SMA and height (m2) were used to calculate skeletal muscle index (SMI = SMA/m2). Skeletal Muscle Gauge (SMG) was created by multiplying SMI x SMD. Differences were compared using two group t-tests and fisher’s exact tests. Results: Of the 70 patients from the original study, 25 had available CT imaging. The mean age was 59, 52% female, 80% Caucasian, and 92% with either stage III or IV disease. Eleven patients (44%) had grade 3/4 toxicity, and 12 patients were identified as sarcopenic (48%) [per Martin et al. JCO 2013]. Sarcopenic patients had numerically higher first cycle 5FU AUCs compared to non-sarcopenic patients (19.3 vs. 17.3 AUC, p= 0.43) and higher grade 3/4 toxicities (50 vs 38.5%, p= 0.70). Patients with low SMG ( < 1475 AU) had higher grade 3/4 toxicities (62 vs 25%, p= 0.11) and higher hematologic toxicities (46 v 8%, p= 0.07). Conclusions: CRC patients with sarcopenia had numerically higher first cycle AUCs of 5FU and a higher incidence of severe toxicities; however, this was not statistically significant, possibly due to limited sample size. SMG, an integrated muscle measure, was more highly correlated with toxicity outcomes than either SMI or SMD alone. Further research exploring the role of body composition in pharmacokinetics is needed with a focus on alternative dosing strategies in sarcopenic patients.
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Arias-Palomo, E., A. Yamashita, I. S. Fernandez, R. Nunez-Ramirez, Y. Bamba, N. Izumi, S. Ohno, and O. Llorca. "The nonsense-mediated mRNA decay SMG-1 kinase is regulated by large-scale conformational changes controlled by SMG-8." Genes & Development 25, no. 2 (January 15, 2011): 153–64. http://dx.doi.org/10.1101/gad.606911.

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Simpson, J. M., Ian Smail, U. Dudzevičiūtė, Y. Matsuda, B.-C. Hsieh, W.-H. Wang, A. M. Swinbank, et al. "An ALMA survey of the brightest sub-millimetre sources in the SCUBA-2–COSMOS field." Monthly Notices of the Royal Astronomical Society 495, no. 3 (January 2020): 3409–30. http://dx.doi.org/10.1093/mnras/staa1345.

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ABSTRACT We present an ALMA study of the ∼180 brightest sources in the SCUBA-2 850-μm map of the COSMOS field from the S2COSMOS survey, as a pilot study for AS2COSMOS – a full survey of the ∼1000 sources in this field. In this pilot study, we have obtained 870-μm continuum maps of an essentially complete sample of the brightest 182 sub-millimetre sources ($S_{850\, \mu \rm m}\gt $ 6.2 mJy) in COSMOS. Our ALMA maps detect 260 sub-millimetre galaxies (SMGs) spanning a range in flux density of $S_{870\, \mu \rm m}$ = 0.7–19.2 mJy. We detect more than one SMG counterpart in 34 ± 2 per cent of sub-millimetre sources, increasing to 53 ± 8 per cent for SCUBA-2 sources brighter than $S_{850\, \mu \rm m}\gt $ 12 mJy. We estimate that approximately one-third of these SMG–SMG pairs are physically associated (with a higher rate for the brighter secondary SMGs, $S_{870\, \mu \rm m}\gtrsim$ 3 mJy), and illustrate this with the serendipitous detection of bright [C ii] 157.74-μm line emission in two SMGs, AS2COS 0001.1 and 0001.2 at z = 4.63, associated with the highest significance single-dish source. Using our source catalogue, we construct the interferometric 870-μm number counts at $S_{870\, \mu \rm m}\gt $ 6.2 mJy. We use the extensive archival data of this field to construct the multiwavelength spectral energy distribution of each AS2COSMOS SMG, and subsequently model this emission with magphys to estimate their photometric redshifts. We find a median photometric redshift for the $S_{870\, \mu \rm m}\gt $ 6.2 mJy AS2COSMOS sample of z = 2.87 ± 0.08, and clear evidence for an increase in the median redshift with 870-μm flux density suggesting strong evolution in the bright end of the 870-μm luminosity function.
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Usuki, F., A. Yamashita, T. Shiraishi, A. Shiga, O. Onodera, I. Higuchi, and S. Ohno. "Inhibition of SMG-8, a subunit of SMG-1 kinase, ameliorates nonsense-mediated mRNA decay-exacerbated mutant phenotypes without cytotoxicity." Proceedings of the National Academy of Sciences 110, no. 37 (August 27, 2013): 15037–42. http://dx.doi.org/10.1073/pnas.1300654110.

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Rosenberg, Jonathan E., Jaegil Kim, Andrew Cherniack, Carrie Sougnez, Matthew Meyerson, Gad Getz, John N. Weinstein, Seth P. Lerner, and David J. Kwiatkowski. "Somatic genomic alterations in urothelial cancer: Results of the Cancer Genome Atlas (TCGA) bladder cancer (BC) analysis." Journal of Clinical Oncology 32, no. 4_suppl (February 1, 2014): 285. http://dx.doi.org/10.1200/jco.2014.32.4_suppl.285.

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285 Background: We report here an integrated analysis of mutation and somatic copy number alterations (SCNAs) in 131 BCs to provide a comprehensive landscape of molecular alterations. Methods: Exon capture, whole exome sequencing (WES), and SNP arrays were performed on 131 MIBCs with no prior chemotherapy treatment, analyzed using the Cancer Genome Atlas Firehose Pipeline, and validated using orthogonal methods. Significantly mutated genes (SMGs) were determined by MutSig v1.5. Recurrent SCNAs were identified via GISTIC 2.0. Consensus non-negative matrix factorization (CNMF) was used to identify SCNA and SMG clusters. Results: 32 genes showed statistically significant levels of recurrent somatic mutation. Known druggable SMGs included FGFR3 (12%), PIK3CA (20%), TSC1 (8%), and ERBB3 (11%). CDKN1A (14%), ERCC2 (12%), RXRA (9%), ELF3 (8%), KLF5 (8%), FOXQ1 (5%), RHOB (5%), PAIP1 (5%), and BTG2 (5%) were not previously reported as SMGs in any other TCGA cancer type. Truncating mutations in 4 SMGs involved in epigenetic regulation (MLL2, ARID1A, KDM6A, and EP300) were significantly enriched. Clustering of both SMGs and focal SNCAs in 125 samples identified three distinct groups. Group A is highly enriched in focal SCNAs in several genes, as well as mutations in MLL2. Group B is enriched in papillary histology, loss of CDKN2A, and alterations in FGFR3. Group C has TP53 mutations, enrichment with RB1 mutations, and amplifications of E2F3 and CCNE1. There were no statistically significant associations between smoking status and the mutational spectrum, frequency of mutation in any SMG, focal SCNAs, or CNMF subtype. Conclusions: Analyses identified potential therapeutic targets in 69% of BCs, including 42% with targets in the PI3K/AKT/mTOR pathway and 45% with targets (including ERBB2) in the RTK/MAPK pathway. Clustering reveals 3 groups with differences in pattern of genomic alteration suggesting the possibility of different pathogenic mechanisms of BC development. Epigenetic regulatory genes were more frequently mutated in urothelial carcinoma than in any common cancer studied to date, suggesting the future possibility of targeted therapy for chromatin abnormalities.
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Liu, Junli, Jianing Wang, and Yanchuan Guo. "Effect of Collagen Peptide, Alone and in Combination with Calcium Citrate, on Bone Loss in Tail-Suspended Rats." Molecules 25, no. 4 (February 12, 2020): 782. http://dx.doi.org/10.3390/molecules25040782.

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Oral administration of bovine collagen peptide (CP) combined with calcium citrate (CC) has been found to inhibit bone loss in ovariectomized rats. However, the protective effects of CP and CP–CC against bone loss have not been investigated in a tail-suspension simulated microgravity (SMG) rat model. Adult Sprague-Dawley rats (n = 40) were randomly divided into five groups (n = 8): a control group with normal gravity, a SMG control group, and three SMG groups that underwent once-daily gastric gavage with CP (750 mg/kg body weight), CC (75 mg/kg body weight) or CP–CC (750 and 75 mg/kg body weight, respectively) for 28 days. After sacrifice, the femurs were analyzed by dual-energy X-ray absorptiometry, three-point bending mechanical tests, microcomputed tomography, and serum bone metabolic markers. Neither CP nor CP–CC treatment significantly inhibited bone loss in SMG rats, as assessed by dual-energy X-ray absorptiometry and three-point bending mechanical tests. However, both CP and CP–CC treatment were associated with partial prevention of the hind limb unloading-induced deterioration of bone microarchitecture, as demonstrated by improvements in trabecular number and trabecular separation. CP–CC treatment increased serum osteocalcin levels. Dietary supplementation with CP or CP–CC may represent an adjunct strategy to reduce the risk of fracture in astronauts.
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Grinwis, Margot E., Christopher D. Sibley, Michael D. Parkins, Christina S. Eshaghurshan, Harvey R. Rabin, and Michael G. Surette. "Macrolide and Clindamycin Resistance in Streptococcus milleri Group Isolates from the Airways of Cystic Fibrosis Patients." Antimicrobial Agents and Chemotherapy 54, no. 7 (April 19, 2010): 2823–29. http://dx.doi.org/10.1128/aac.01845-09.

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ABSTRACT Organisms belonging to the Streptococcus milleri group (SMG) are known for their role in pyogenic infections but have recently been implicated as etiological agents of pulmonary exacerbation in adult patients with cystic fibrosis (CF). The prolonged exposure of CF patients to antibiotics prompted us to investigate the susceptibility profiles of 118 SMG isolates from the airways of CF patients to 12 antibiotics compared to 43 SMG isolates from patients with invasive infections. We found that ∼60% of all isolates failed to grow using the standard medium for disc diffusion, Mueller-Hinton blood agar (MHBA), so we explored the usefulness of brain heart infusion (BHI) agar for susceptibility testing. Zone-of-inhibition comparisons between BHI and MHBA showed strong correlations for six antibiotics, and interpretations were similar for both medium types. For ceftriaxone and cefepime, both groups of isolates were highly susceptible. Tetracycline resistance levels were comparable between the two groups (22% in CF isolates and 17.4% in invasive isolates). However, more than half of the CF isolates were not susceptible to azithromycin, erythromycin, and clindamycin, compared to 11%, 13%, and 6.5% of invasive isolates, respectively. There were 5-fold and 8-fold increased risks of azithromycin and clindamycin resistance, respectively, for the isolates from the airways of CF patients relative to the invasive isolates. Macrolide resistance was strongly linked to chronic azithromycin therapy in CF patients. This study shows that BHI agar is a suitable alternative for antimicrobial susceptibility testing for the SMG and that SMG isolates from the airways of CF patients are more resistant to macrolides and clindamycin than strains isolated from patients with invasive infections.
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Dissertations / Theses on the topic "Smg-8"

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Rosains, Jacqueline. "Modulation of pha-4/FoxA and C. elegans Foregut Development by the Novel Gene smg-8." Thesis, Harvard University, 2012. http://dissertations.umi.com/gsas.harvard:10379.

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FoxA transcription factors are central regulators of gut development in all species. In C. elegans, pha-4/FoxA is necessary to generate cells of the foregut, or pharynx. FoxA factors need to be precisely regulated for proper development, yet we know very little about FoxA regulation. To look for potential genes that act as pha-4 regulators, the Mango lab previously conducted two screens for suppressors of the lethality associated with a partial loss of pha-4 activity. Both screens uncovered smg-8, a novel gene that is highly conserved amongst metazoans. Interestingly, the human homolog of smg-8 is amplified in some breast cancers, which also depend on FoxA1. This observation makes smg-8 a very exciting gene to investigate. The goal of my thesis is to analyze smg-8 to better understand its function and potential role as a candidate regulator of pha-4/FoxA, using C. elegans as a model system. In this thesis, I show that C. elegans smg-8 does not have a role in the Nonsense Mediated Decay pathway. I find that smg-8 modulates pha-4 protein levels during embryonic development. This work is the first direct evidence that smg-8 is a modulator of pha-4. I used biochemical and bioinformatic approaches to uncover possible partners of smg-8. These approaches identified several interesting candidates that will help place C. elegans smg-8 in a functional pathway. This work has expanded our understanding of smg-8 function and lays the foundation for further investigation of the role of this novel gene as a regulator of pha-4/FoxA in C. elegans.
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Castro, Cláudia Irene Emilio de. "Alterações cariotípicas dos cromossomos 7 e 8 em Síndromes Mielodisplásicas de novo (SMD-p) e sua correlação com variáveis biológicas de significado prognóstico." Universidade de São Paulo, 2002. http://www.teses.usp.br/teses/disponiveis/9/9136/tde-24042015-150822/.

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As Síndromes Mielodisplásicas (SMD) são doenças clonais, que se originam em células hemopoéticas totipotentes, com distúrbio na proliferação e perda da maturação celular gerando hipercelularidade na medula óssea (MO) e citopenias no sangue periférico (SP). As SMD ocorrem predominantemente em pacientes mais vellhos e estão associadas com um alto risco de progressão para leucemia mielóide aguda (LMA). A etiologia das SMD é deconhecida na maioria dos casos (de novo), porém 10% das SMD estão associadas ao uso de agentes xenobioticos, como os agentes antineoplásicos e solventes orgânicos (SMD secundária). Os pacientes com SMD apresentam diferente evolução clínica, embora todos sejam incuráveis. Alguns pacientes podem viver por uma década com apenas uma anemia enquanto outros apresentam uma sobrevida curta devido à uma rápida evolução para LMA. Diferentes aspectos biológicos da doença têm sido usados para dividir os pacientes em grupos e auxiliado nas decisões clínicas a serem tomadas em cada caso. A maioria dessas classificações levam em conta os subtipos morfológicos (classificação FAB) e os dados citogenéticos do clone mielodisplásico. Anormalidades cromossômicas são importantes marcadores das SMD. A maioria dos pacientes com esta síndrome apresenta aberrações citogenéticas que podem auxiliar no diagnóstico das SMD. Entretanto, algumas dessas aberrações podem ser correlacionadas com um mau prognóstico, como a monossomia do 7 e a trissomia do 8. Essas aneuploidias têm sido investigadas por estudos citogenéticos convencionais (bandamento G) e moleculares (\"FISH\" - Hybridization in situ Fluorescente). No intuito de se comparar a eficiência de ambas as técnicas e de se definir a freqüência e o significado prognóstico da monossomia do 7 (-7) e trissomia do 8 (+8) em SMD, foram estudados 28 pacientes com SMD-p (17 homens e 11 mulheres) por citogenética convencional (banda G) e molecular (\"FISH\" em intérfase), previamente a tratamento quimioterápico. Para compararmos o estudo cariotípico por bandamento G com o de \"FISH\", 19 pacientes foram estudados e a -7 foi detectada por \"FISH\" em seis pacientes e somente um deles o foi pela citogenética convencional. Os pacientes com -7 apresentaram uma menor sobrevida e um maior risco de transformação leucêmica. Cinco dos seis pacientes com -7 foram previamente classificados (FAB) como subtipos de mau prognóstico. Dois pacientes apresentaram +8, detectada por ambas as técnicas. Não houve diferença na sobrevida destes pacientes. Nossos resultados demonstraram que o \"FISH\" é uma técnica mais eficiente para detectar anomalias cromossômicas numéricas (-7) com importância prognóstica, especialmente em amostras pobres em metáfases, uma vez que \"FISH\" pode ser realizado em núcleos interfásicos.
Myelodisplastic Syndromes (MDS) are clonal disordes of hematopoietic stem cells characterized by ineffective hematopoiesis leading to blood cytopenias. They predominate in elderly patients and are associated with a high risk of progression to acute myelogenous leukemia (AML). The etiology of MOS is unknown in most cases (de novo) but about 10% of MDS are secondary to the use of xenobiotics, such as antineoplastic agents and organic solvents (secondary MDS). Though incurable, MDS patients have different clinical courses. Some patients can live for a decade with anemia being the only complaint whilst others present a very short term survival due to a rapid development of a treatment-refractory AML. Scales taking in account different biological aspects of the disease have been used in order to allocate patients in discrete risk levels. This risk stratification might help clinical decisions in a patient-by-patient basis. Most of these scales take in account the morphological subtype (FAB classification) and the cytogenetic status of the myelodysplastic clone. Chromosome abnormalities are very important markers of MDS. Most patients with this syndrome present cytogenetic aberrations which can be helpful in the diagnosis of SMD. Moreover, some of these aberrations have been correlated to a poorer prognosis, such as monosomy 7 and trissomy 8. These aneuploidies have been investigated by conventional (G-Banding) and molecular cytogenetic studies (In Situ Hybridization - FISH). In order to compare the efficiency of both techniques and to define the frequency and significance of monosomy 7 and trisomy 8 in MDS in a single institution population, chromosome studies of 28 patients were performed in metaphases by G-banding and in interphases by FISH (α satellite probes), before chemotherapy treatment. Chromosome studies by both techniques were obtained for 19 patients; monosomy 7 was detected by FISH in 6 patients; only one of these has been detected by conventional cytogenetics. Clinical follow-up of this monosomy 7 group patients disclosed short survival and increased risk for developing AML. Five out of the six patients with monosomy 7 were previously classified as the FAB subtypes of poor prognostic. 2 patients presented trisomy 8 in this series and were detected by both techniques. No difference in survival could be seen in these patients. Our results demonstrate that FISH is much more efficient to investigate chromosome numerical anomaly (at least monossomy 7) with prognostic relevance. This is specially true mainly when bone marrow samples lack metaphases since the studies can be performed in interphases cells.
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Mojžíš, Martin. "Nízkohlučné povrchy vozovek." Master's thesis, Vysoké učení technické v Brně. Fakulta stavební, 2013. http://www.nusl.cz/ntk/nusl-226453.

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Master´s thesis is interested in the problems of low-noise road surfaces. The theoretical part describes noise, sources of noise, the low-noise road surfaces and the practical part describes two proposals of low-noise stone mastic asphalt SMA 8 LA.
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Bárta, Jan. "Nízkohlučné vozovky." Master's thesis, Vysoké učení technické v Brně. Fakulta stavební, 2014. http://www.nusl.cz/ntk/nusl-226619.

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Master´s thesis describestheproblemsoflow-noiseroadsurfaces. Thetheoretical part describestrafficnoise, sourcesofnoise, thelow-noiseroadsurfaces and thepractical part - describestwoproposalsoflow-noise stone masticasphalt SMA 8 LA and Düsseldorflow-noise stone asphalt LOA 5.
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GOSSELIN, ANNIE. "Mise au point d'une source d'ions de recul pompee par ganil-sme en vue d'etudier des collisions ions-atomes a tres base energie : application aux collisions ar#8#++he." Caen, 1993. http://www.theses.fr/1993CAEN2006.

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Dans le but d'etudier les collisions ions-atomes a basse energie, nous avons realise une source d'ions de recul. Ces ions de recul sont produits par impact de faisceaux issus de la sortie moyenne energie du ganil sur une cible gazeuse. Un dispositif electrostatique et magnetique permet d'extraire, de guider et de selectionner ces ions de recul. Nous indiquons la facon d'operer afin de former des faisceaux les plus intenses possible, de bonne qualite optique tout en conservant une faible dispersion en energie. Afin d'etudier les collisions de ces ions avec une cible gazeuse formee par un jet supersonique, nous avons mis au point trois dispositifs d'analyse qui permettent les mesures des sections efficaces totales, partielles, differentielles en angle, d'echange de charge. A l'aide de deux de ces dispositifs, nous avons mesure les sections efficaces totales de simple capture pour les collisions ar#q#++he pour 6q12 pour une energie de collision de 300 qev ainsi que pour q=6 et 8 pour des energies de collision de 50 a 300 qev. Ensuite, nous avons mesure les sections efficaces partielles de simple capture pour la collision ar#8#++he pour des energies de collisions de 50 a 300 qev. Nous avons egalement effectue une etude de cette collision avec les modeles theoriques a notre disposition afin d'effectuer une comparaison avec nos resultats experimentaux
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MANIFACIER, LAURENT. "Etude des correlations entre proprietes physiques et cristallographiques dans les supraconducteurs a haute temperature critique de type (bi,pb)#2sr#2(ca,tr)cu#2o#8#+#x(tr=y,la,nd,pr,sm)." Paris 11, 1998. http://www.theses.fr/1998PA112118.

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La complexite des supraconducteurs a haute tc necessite entre autres la comprehension du mecanisme de transfert de charges. Si l'universalite du diagramme de phases representant la tc en fonction du nombre de porteurs n'est pas a remettre en cause, il convient de se poser d'autres questions. Les variations de tc observees sont-elles seulement le fait d'un changement de la concentration en porteurs dans le plan, ou bien egalement de leur mobilite dans l'axe c ou bien encore d'une conductivite dans les reservoirs de charges ? de recents travaux soulevent de plus en plus le probleme pose par un crossover 3d-2d au niveau de l'optimum de tc. Afin de tenter d'apporter quelques elements de reponse, des etudes cristallographiques (affinements de structure) et magnetiques (susceptibilite diamagnetique) furent effectuees sur la substitution du plomb et d'elements de terres rares dans le systeme bi-2212. La tc est tres peu affectee par les diverses substitutions cationiques. Les mesures cristallographiques, prenant en compte les modulations incommensurables, revelent trois regimes distincts dans les parametres de la structure interne de ces materiaux. Ils coincident avec les regimes sur-dope, sous-dope et isolant. L'etude de la transition supraconductrice par susceptibilite diamagnetique conduit a interpreter ces evolutions comme une localisation des porteurs (diminution de l'exclusion diamagnetique) plutot que d'une diminution de la densite de trous due a la substitution de l'yttrium. La substitution par le plomb retablit au contraire la conductivite 3d. Dans cette approche, les phases sur-dopees, sous-dopees et isolantes dependraient a la fois de de la densite de porteurs, de leur mobilite et de l'etat physique des reservoirs de charges. La tc, et donc le transfert de charges, restent globalement constants en fonction des diverses substitutions.
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Ευαγγελίου, Νικόλαος, and Πέτρος Γιαταγάνας. "Κατάσκευη και έλεγχος ρομποτικού πολυαρθρωτού εργαλείου με χρήση έξυπνων υλικών." Thesis, 2011. http://nemertes.lis.upatras.gr/jspui/handle/10889/4688.

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Ο στόχος αυτής της εργασίας είναι να αποκτήσουμε μία βασική γνώση όλων των διαφορετικών σχεδιαστικών παραμέτρων που πρέπει να εξεταστούν για να είναι εφικτή η κατασκευή και ο έλεγχος ενός πολυαρθρωτού εργαλείου. Επιπλέον, όλες οι αναλυτικές μέθοδοι ελέγχου που βασίζονται στις ιδιαιτερότητες των SMA παρουσιάζονται λεπτομερώς, ώστε να παραχθεί μία ικανοποιητική λύση βασιζόμενη στις μεταβολές κατάστασης των κραμάτων και του συγκεκριμένου βραχίονα. Με άλλα λόγια, μία πλήρης γνώση του πώς σχεδιάζουμε, κατασκευάζουμε, προσομοιώνουμε, ελέγχουμε και απεικονίζουμε ένα λειτουργικό μικροσκοπικό πολυαρθρωτό βραχίονα, με τένοντες βασισμένους σε SMA για ελάχιστα επεμβατική χειρουργική είναι ο στόχος της παρούσας εργασίας.
The purpose of this work is to acquire a fundamental knowledge of all the different design parameters, which must be evaluated in order to be able to fabricate and control a multi-DOF manipulator. Moreover, all the analytical control techniques based on the particularities of the shape memory alloys will be shown in details, in order to provide an efficient solution based on the variations of the alloys and the specific manipulator. In other words, the knowhow of building, evaluating, controlling and displaying a functional tiny multi- DOF SMA-based manipulator for minimally invasive surgery is the purpose of this work.
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Books on the topic "Smg-8"

1

Zetex. Semiconductor data book: SM-8 (8 lead SOT223). 2nd ed. Chadderton: Zetex, 1995.

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Works, United States Congress Senate Committee on Environment and Public. Border Smog Reduction Act of 1998: Report (to accompany H.R. 8). [Washington, D.C: U.S. G.P.O., 1998.

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Nauchno-prakticheskai︠a︡ konferent︠s︡i︠a︡ Svoboda slova--voprosy formirovanii︠a︡ sovremennoĭ mediapolitiki (2006 Dushanbe, Tajikistan). Svoboda SMI: Voprosy formirovanii︠a︡ sovremennoĭ mediapolitiki, materialy respublikanskoĭ nauchno-prakticheskoĭ konferent︠s︡ii (8 dekabri︠a︡ 2006 goda). Dushanbe: Master print, 2007.

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Nauchno-prakticheskai︠a︡ konferent︠s︡i︠a︡ Svoboda slova--voprosy formirovanii︠a︡ sovremennoĭ mediapolitiki (2006 Dushanbe, Tajikistan). Svoboda SMI: Voprosy formirovanii︠a︡ sovremennoĭ mediapolitiki, materialy respublikanskoĭ nauchno-prakticheskoĭ konferent︠s︡ii (8 dekabri︠a︡ 2006 goda). Dushanbe: Master print, 2007.

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SME World Congress on the Human Aspects of Automation (1985 Cambridge, Mass.). 1985 SME World Congress on the Human Aspects of Automation: Conference, September 8-11, 1985, Cambridge, Massachusetts. Dearborn, Mich: Society of Manufacturing Engineers, 1985.

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Anton, Morozov, Sultanov B. K, Syrtqy sai︠a︡sat zhăne taldau ortalyghy (Kazakhstan), and Friedrich-Ebert-Stiftung, eds. Sbornik materialov po itogam Mezhdunarodnoĭ konferent︠s︡ii "Vneshni︠a︡i︠a︡ politika Respubliki Kazakhstan v zerkale otechestvennykh i zarubezhnykh SMI": 8 okti︠a︡bri︠a︡ 2001g. Almaty: T︠S︡entr vneshneĭ politiki i analiza, 2001.

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Gold Forum on Technology and Practices (1st 1989 Reno, Nev.). Gold Forum on Technology and Practices - World Gold '89: Proceedings of the first joint international meeting between SME and AusIMM, Nov. 5-8, 1989, Reno, Nevada. Edited by Bhappu Roshan Boman, Harden Rod J, Society for Mining, Metallurgy, and Exploration (U.S.), and Australasian Institute of Mining and Metallurgy. Littleton, Colo: Society for Mining, Metallurgy, and Exploration, 1989.

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K, Liaw P., Pitchumani R, and TMS/ASM Joint Composite Materials Committee., eds. Physical properties of composites: Proceedings of symposium sponsored by the ASM-TMS Composite Committee (SMD), held during the 125th TMS Annual Meeting and Exhibition, Anaheim, CA, February 4-8, 1996. Warrendale, Pa: Minerals, Metals & Materials Society, 1996.

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Express. Daily Express Sm Crossword Vol 8. Headline Book Publishing, 1994.

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Sonrise-T-Shirt SM 6-8. Gospel Light Publications, 1997.

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Book chapters on the topic "Smg-8"

1

Crucho, João, José Neves, and André Pedro. "Mechanical Behavior of SMA 8 Modified with Nano Hydrotalcite." In Infrastructure Sustainability Through New Developments in Material, Design, Construction, Maintenance, and Testing of Pavements, 1–10. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-79644-0_1.

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Ramesh, Rashmi. "SM Higgs Exclusion and Anomalous Spin Zero HVV Couplings of the Higgs Boson in Proton Collisions at 7 TeV and 8 TeV." In Springer Proceedings in Physics, 219–21. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-21191-6_22.

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Wang, Yan Xiang, C. Fang, Min Tang, Hong Qiu, and Zhao Xian Xiong. "Preparation and Dielectric Properties of Sm3+-Substituted SrBi8Ti7O27 Based Microwave Ceramics." In High-Performance Ceramics III, 95–98. Stafa: Trans Tech Publications Ltd., 2007. http://dx.doi.org/10.4028/0-87849-959-8.95.

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Qin, N., and X. M. Chen. "Modification of Ba6-3xSm8+2xTi18O54 (x=2/3)Microwave Dielectric Ceramics by Nd/Bi Co-Substitution on A-Site." In High-Performance Ceramics III, 57–60. Stafa: Trans Tech Publications Ltd., 2007. http://dx.doi.org/10.4028/0-87849-959-8.57.

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Zheng, Yong, Wen Lei, Hai Jian Bu, and Xing Zhong Zhao. "Fabrication of Ba6-3x(Sm0.2Nd0.8)8+2xTi18O54(x=2/3) Ceramics by Solid State Reaction." In Key Engineering Materials, 258–61. Stafa: Trans Tech Publications Ltd., 2007. http://dx.doi.org/10.4028/0-87849-410-3.258.

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"Module 8 SMS Policy." In Safety Management Systems for Aviation Practitioners: Real-World Lessons, 113–26. Reston, VA: American Institute of Aeronautics and Astronautics, Inc., 2013. http://dx.doi.org/10.2514/5.9781624102110.0113.0126.

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"8. SME Development in ASEAN." In ASEAN Economic Community Scorecard, 163–81. ISEAS Publishing, 2013. http://dx.doi.org/10.1355/9789814414296-012.

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"Chapter 8: Advanced SMC of Microgrids." In Advanced and Optimization Based Sliding Mode Control: Theory and Applications, 205–62. Philadelphia, PA: Society for Industrial and Applied Mathematics, 2019. http://dx.doi.org/10.1137/1.9781611975840.ch8.

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Herbst, Edward P., and Frank Schorfheide. "Combining Particle Filters with SMC Samplers." In Bayesian Estimation of DSGE Models. Princeton University Press, 2015. http://dx.doi.org/10.23943/princeton/9780691161082.003.0010.

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This chapter combines the SMC algorithm with the particle filter approximation of the likelihood function to develop an SMC2 algorithm. As with the PFMH algorithm, the goal is to obtain a posterior sampler for the DSGE model parameters for settings in which the likelihood function of the DSGE model cannot be evaluated with the Kalman filter. The starting point is the SMC Algorithm 8. The chapter adds data sequentially to the likelihood function rather than tempering the entire likelihood function. Moreover, the evaluation of the incremental and the full likelihood function in the correction and mutation steps of Algorithm 8 are replaced by the evaluation of the respective particle filter approximations.
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Cougnon, Louise-Amélie, and Jean-Léon Bouraoui. "8. Orality and Literacy of Telephony and SMS." In Manual of Romance Languages in the Media, edited by Kristina Bedijs and Christiane Maaß. Berlin, Boston: De Gruyter, 2017. http://dx.doi.org/10.1515/9783110314755-009.

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Conference papers on the topic "Smg-8"

1

Samotaev, N. N., K. Y. Oblov, and A. V. Ivanova. "P1SM.8 - Technology of Rapid Prototyping SMD MOX Gas Sensors." In 17th International Meeting on Chemical Sensors - IMCS 2018. AMA Service GmbH, Von-Münchhausen-Str. 49, 31515 Wunstorf, Germany, 2018. http://dx.doi.org/10.5162/imcs2018/p1sm.8.

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Remot, Diane B., Joshua John P. Consulta, Mark Joseph M. Lasaca, and Neil Anthony L. Ontuca. "Online Portal Inquiry for DOST-8(Department of Science and Technology-Region 8) Programs and Services with SMS Features." In 2019 IEEE 11th International Conference on Humanoid, Nanotechnology, Information Technology, Communication and Control, Environment, and Management ( HNICEM ). IEEE, 2019. http://dx.doi.org/10.1109/hnicem48295.2019.9073497.

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Ozbek, Simon, Esther Foo, J. Walter Lee, Nicholas Schleif, and Brad Holschuh. "Low-Power, Minimal-Heat Exposure Shape Memory Alloy (SMA) Actuators for On-Body Soft Robotics." In 2019 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/dmd2019-3287.

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In the world of soft-robotic medical devices, there is a growing need for low profile, non-rigid, and lower power actuators for soft exoskeletons and dynamic compression garments. Advanced compression garments with integrated shape memory materials have been developed recently to alleviate the functional and usability limitations associated with traditional compression garments. These advanced garments use contractile shape memory alloy (SMA) coil actuators to produce dynamic compression on the body through selective heating of the SMA material. While these garments can create spatially- and temporally-controllable compression, typical SMA materials (e.g., 70°C Flexinol) consume considerable power and require considerable thermal insulation to protect the wearer during the heating phase of the SMA actuation. Alternative SMA materials (e.g., NiTi #8 by Fort Wayne Metals, Inc.) transform below room temperature and do so using no applied electrical power and generate no waste heat. However, these materials are challenging to dynamically control and require active refrigeration to reset to material. In theory, low-temperature SMA actuators made from materials like NiTi #8 may maintain additional dynamic actuation capacity once equilibrated to room temperature (i.e., the material may not fully transform), as the SMA phase transformation temperature window expands when the material experiences applied stress. This paper investigates this possibility: we manufactured and tested low-temperature NiTi coil actuators to determine the magnitude of the additional force that can be generated via Joule heating once the material has equilibrated to room temperature. SMA spring actuators made from NiTi #8 consumed 84% less power and stabilized at significantly lower temperatures (26.0°C vs. 41.2°C) than SMA springs made from 70°C Flexinol, when actuated at identically fixed displacements (100% nominal strain) and when driven to produce equal forces (∼3.35N). This demonstration of low-power, minimal-heat exposure SMA actuation holds promise for many future wearable actuation applications, including dynamic compression garments.
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Ott, Hubert, and John Nylander. "Ultra-Thin Automotive Lamps (8-12mm) Using Special SMT LEDs and Special Optics." In SAE 2002 World Congress & Exhibition. 400 Commonwealth Drive, Warrendale, PA, United States: SAE International, 2002. http://dx.doi.org/10.4271/2002-01-0383.

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Braden, Paul, and Kaitlyn Gainer. "Application of the Shape Memory Effect to Restore Smoothness." In ASME 2015 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/smasis2015-8827.

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A major worldwide industry is the display and preservation of historical and rare documents, paintings, canvases, tapestries and other works of art. Many private collectors and museums pay large amounts, such as the $23 million for the U.S. National Gallery and $8 million for the U.S. National Archives. There is an even greater demand for many consumers who desire an affordable way to safely maintain their images in top condition for viewing and enjoyment. Another industry where the smoothness of the paper documents is important is in the shipping and delivery business. Here, many shipments are done with cylindrical tubes that cause the paper to appear bent and not flat. In some cases, this can pose a major problem for scanning and electronic devices which need a flat surface for optimal performance. A novel new alternative to traditional conservation methods is the use of Shape Memory Alloys (SMA’s) to remove wrinkles and other surface anomalies. SMA’s use a thermoelastic property called the Shape Memory Effect (SME) to recover large strains by phase transformation. In this process, the SMA is stretched until the polycrystalline microstructure is detwinned Martensite. Then, energy in the form of heat is applied to the SMA which causes the phase transformation to the more compact Austenite. Thus, a reverse method is the proposed solution for the complex problem faced by art preservation experts. Instead of using large clamps and having to wait for results, we demonstrate how embedded SMA wires in a robust picture frame can provide a continuous restorative force that maintains the picture’s smoothness. Using proper simple wiring from the SMA wires to the picture, it is possible to remove the strains in the paper and hold the picture to the proper smoothness long term. We provide experimental results and offer suggestions for the future use of SMA’s in this new field of art restoration.
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Lawrence, S. "SUAS for 8-channel GMTI radar using alternative high performance non-SMI STAP algorithm." In 2012 IEEE 7th Sensor Array and Multichannel Signal Processing Workshop (SAM). IEEE, 2012. http://dx.doi.org/10.1109/sam.2012.6250526.

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Haris, Muhammad, Jianjun Yu, and Gee Kung Chang. "8×10 Gbit/s WDM repeaterless transmission over 240km SMF using modified duobinary RZ signals." In 2006 Conference on Lasers and Electro-Optics and 2006 Quantum Electronics and Laser Science Conference. IEEE, 2006. http://dx.doi.org/10.1109/cleo.2006.4628114.

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8

RIVA, FRANCESCO. "12 CLOSED DOORS AND 8 OPEN WINDOWS IN PHYSICS BEYOND THE SM." In XXIXth International Workshop on High Energy Physics. WORLD SCIENTIFIC, 2014. http://dx.doi.org/10.1142/9789814578745_0001.

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Czechowicz, Alexander, Peter Dültgen, and Sven Langbein. "Adaptive Elastic SMA Elements for Damping Applications." In ASME 2013 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/smasis2013-3052.

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Shape memory alloys (SMA) are smart materials, which have two technical usable effects: While pseudoplastic SMA have the ability to change into a previously imprinted actual shape through the means of thermal activation, pseudoelastic SMA show a reversible mechanical elongation up to 8% at constant temperature. The transformation between the two possible material phases (austenite and martensite) shows a hysteretic behavior. As a result of these properties, SMA can be used as elastic elements with intrinsic damping function. Additionally the electrical resistance changes remarkably during the material deformation. These effects are presented in the publication in combination with potential for applications in different branches at varying boundary conditions. The focus of the presented research is concentrated on the application of elastic elements with adaptive damping function. As a proof for the potential considerations, an application example sums up this presentation.
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10

Rosa, P., N. J. Murray, R. S. Bhamber, J.-D. Ania-Castañón, and P. Harper. "Unrepeatered 8 × 40Gb/s Transmission Over 320km SMF-28 Using Ultra-long Raman Fibre Laser Based Amplification." In European Conference and Exhibition on Optical Communication. Washington, D.C.: OSA, 2012. http://dx.doi.org/10.1364/eceoc.2012.p4.04.

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Reports on the topic "Smg-8"

1

Reyes, Angela, Benjamin Roseth, and Diego A. Vera-Cossio. Research Insights: How Digital Tools Increase Access to Government Services and Social Programs through On-time Renewals of IDs. Inter-American Development Bank, August 2021. http://dx.doi.org/10.18235/0003572.

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Sending SMS reminders increased the probability of on-time renewals of IDs by 12 percentage points, while also allowing citizens to renew their IDs online only increased renewals by 8 percentage points. Providing an online option (instead of in-person renewals) was less effective due to a poor user experience with the online procedure. The poorest individuals who received reminders were also more likely to receive transfers from an emergency in-kind transfer delivered through digital vouchers.
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