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Dissertations / Theses on the topic 'SMOC'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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1

Sexton, David James. "Investigating the functional role of SMOC-1 in zebrafish." Thesis, University of Edinburgh, 2016. http://hdl.handle.net/1842/22907.

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True anophthalmia is the most severe congenital eye malformation. With absence of the eye, optic nerve, chiasm and optic tracts. Identifying the genes that cause genetic true anophthalmia should improve our understanding of the critical processes required for development of the eye. Recessive loss-of-function mutations in SMOC1 have been identified as the cause of Ophthalmo-acromelic syndrome (OAS), a multisystem disorder which has true anophthalmia as a prominent feature with characteristic limb and facial malformations. In order to establish the function of SMOC1 in development I used the ze

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2

Silva, Janice Henriques da. "Efeito dos anestésicos inalatórios no transportador de dopamina em fatias de córtex cerebral de ratos." Universidade Federal de Minas Gerais, 2006. http://hdl.handle.net/1843/SMOC-6W8MRD.

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Inhalatory anesthetics affect synaptic transmission, but little is known about their actions in the central nervous system. Dopamine is a catecholaminergic neurotransmitter that has important functions in the central nervous system and it is possible that its release can be modulated by inhalatory anesthetics. The study of inhalatory anesthetics effects in the neurotransmitter release could provide further information about the mechanisms that contribute with the actions of these agents during anesthesia. In this study, cortical slices of rat brain were labeled with [3H] dopamine to observe t

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3

Miranda, Debora Marques de. "Estudo de associação entre Síndrome de Tourette e genes da via Slit-Robo." Universidade Federal de Minas Gerais, 2006. http://hdl.handle.net/1843/SMOC-6ZCHQX.

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Tourette syndrome (TS) is a neuropsichyatric disorder characterized by tics and familiar inheritance. Several research groups are investigating the genetic aspects of TS, however, frequently the findings are not replicated in subsequent studies. Study of gene Slit and trk-like family member 1 (SLITRK1) has shown correlation with TS in three non-related patients. The family of SLIT proteins and their receptors, the robo family, are involved in axonal guidance in the crossing over at the spinal cord. The objective of our study was to further elucidate the putative role of Slit-Robo pathway in TS

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4

Rosa, Daniela Valadao Freitas. "Expressão de DARPP-32 e NCS-1 em cérebros de ratos submetidos à estimulação eletroconvulsiva." Universidade Federal de Minas Gerais, 2005. http://hdl.handle.net/1843/SMOC-7PBPKT.

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Conhecidos há aproximadamente 2500 anos, os transtornos do humor continuam a dominar o interesse da saúde pública. Cerca de 5% dos pacientes depressivos não respondem a qualquer medida farmacológica e/ou psicoterápica. Para esses pacientes, a eletroconvulsoterapia (ECT) constitui uma importante oportunidade de melhora.Indução de convulsões na forma de ECT tem sido usada no tratamento de desordens psiquiátricas por mais de 60 anos. As principais indicações diagnósticas incluem depressão, mania, catatonia e esquizofrenia. Devido às dificuldades na identificação dos mecanismos de ação da ECT, tê

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5

Domingues, Stefany Fontes. "Caracterização das interações protéicas envolvidas no tráfego celular do transportador de colina de alta afinidade - CHT1." Universidade Federal de Minas Gerais, 2006. http://hdl.handle.net/1843/SMOC-6W7NGY.

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The high affinity choline transporter (CHT1) is responsible for choline uptake, which is derived from acetylcholine degradation, in the synaptic cleft of cholinergic neurons. CHT1 activity is very important since cholinergic neurons have very low ability to synthesize acetylcholine de novo. Although CHT1 is mainly a plasma membrane transporter, it is found predominantly recycling between intracellular vesicles and the cell surface. Cellular trafficking seems to play an important role in the transporter activity. In the present experiments, we identified proteins that might interact with CHT1,

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6

Silva, Cristina Martins e. "Avaliação neuroquímica do sistema colinérgico de camundongos com o gene do transportador vesicular de acetilcolina (VAChT) modificado geneticamente." Universidade Federal de Minas Gerais, 2008. http://hdl.handle.net/1843/SMOC-7JAPKY.

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The vesicular acetylcholine transporter (VACht) is responsible for acetylcholine (Ach) storage in synaptic vesicles, an important step for cholinergic transmission. Our goal was to study the role of VAChT in cholinergic tonus maintenance through the generation of mice presenting alterations in VAChT gene by homologous recombination.. One of used strategies was the insertion of a neomycin resistance cassette in untranslated 5 region of VAChT gene. This genetic modification generated mice HET HOM presenting reduced expression of VAChT (VAChT Knockdown). KD and KD present a 45% and 65% de

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7

Guimaraes, Andre Luiz Sena. "Estudo da associação entre Estomatite Ulcerativa Recorrente, Síndrome da Ardência Bucal e polimorfismos funcionais nos genes SLC6A4, IL1B,IL6,IL10, TNFA." Universidade Federal de Minas Gerais, 2006. http://hdl.handle.net/1843/SMOC-6Z3P3N.

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Este trabalho teve como objetivo geral investigar uma possível associação entre cinco polimorfismos genéticos funcionais em duas doenças bucais de etiologias diferentes em pacientes brasileiros. Para isto, a tese foi dividida em três artigos. No primeiro, foi avaliada a associação entre os polimorfismos genéticos IL-1B +3954 (C/T) e 5HTTLPR com a Síndrome da Ardência Bucal (SAB). Para este estudo foi extraído o DNA de trinta pacientes com SAB e trinta e um controles. Não observamos diferença estatística entre os grupos quanto à distribuição do polimorfismo 5-HTTLPR (P=0.60), por outro l

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8

Pimenta, Flavio Juliano Garcia Santos. "Análise molecular do gene WWOX em leucoplasia bucal." Universidade Federal de Minas Gerais, 2008. http://hdl.handle.net/1843/SMOC-7DQQ8B.

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Leucoplasia bucal é a lesão cancerizável mais comum da cavidade bucal com índice de transformação maligna variando de 1 a 18%. Atualmente, os principais parâmetros para predição de malignização em leucoplasias são as características clínicas associadas com os achados histopatológicos. Contudo, esses indicadores não conseguem determinar com precisão quais lesões irão sofrer transformação maligna, sendo necessária a descoberta de marcadores biológicos com essa função. Estudos recentes têm demonstrado que alterações moleculares no gene supressor de tumor WWOX, localizado no cromossomo 16, na reg

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9

Fumagalli, Miguel Angel Chavez. "Proteção contra a infecção por Leishmania (Leishmania) amazonensis pela imunização de camundongos BALB/c com peptídeos sintéticos selecionados por phage display e spot synthesis." Universidade Federal de Minas Gerais, 2008. http://hdl.handle.net/1843/SMOC-7PBJ9K.

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Leishmania amazonensis é um dos principais agentes etiológicos em um amplo espectro de formas clínicas de leishmanioses e apresenta uma ampla distribuição geográfica nas Américas, que coincide com áreas comuns de transmissão de outras espécies de Leishmania. Neste trabalho, a eficácia protetora induzida pela imunização com o polímero formado por dois peptídeos sintéticos selecionados pelas técnicas de Phage Display e Spot synthesis foi avaliada em camundongos BALB/c contra a infecção desafio com L. amazonensis. Os peptídeos foram selecionados utilizando anticorpos da classe IgG purificados a p

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10

Ferreira, Lucimar Teodoro. "Sinais de tráfego envolvidos no envolvidos no endereçamento do transportador vesicular de acetilcolina (VAChT)." Universidade Federal de Minas Gerais, 2006. http://hdl.handle.net/1843/SMOC-6Y6N55.

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The vesicular acetylcholine transporter (VAChT) is the protein responsible for packaging cytoplasmic acetylcholine (ACh) into the synaptic vesicle of cholinergic neurons. The cytosolic C-terminal region of VAChT is important in intracellular trafficking events and targeting to secretory organelles. In this study, we evaluate the existence of trafficking signals in this region. Using confocal microscopy and GFP (green fluorescent protein) as a molecular label, the intracellular trafficking of several VAChT constructs was observed. Our results suggest that amino acids 471-490 contain important s

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11

Magalhaes, Ana Cristina Ribeiro. "Internalização e tráfego de PrPs." Universidade Federal de Minas Gerais, 2005. http://hdl.handle.net/1843/SMOC-6XLP4M.

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Cellular prion protein (PrPsen ou PrPc) is expressed in a wide variety of cells, specialy neurons. This protein is rich in alpha helix structures, but it can assume an alternative conformational isoform known as PrPres (or PrPsc). PrPres presents mainly beta sheet structure and gains the ability to form aggregates as well as is protease resistant. PrPres is able to propagate by converting PrPsen molecules to the alternative conformation isoform PrPres in a new biologic mechanism, not yet fully understood. Then, PrPres molecules form aggregates that accumulates in the brain causing Prion Diseas

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12

Souza, Bruno Rezende de. "A modulação da via cAMP / PKA pelo sensor neural de cálcio - 1 independe de receptores de dopamina." Universidade Federal de Minas Gerais, 2007. http://hdl.handle.net/1843/SMOC-7DGMYG.

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Neuronal calcium sensor-1 (NCS-1) is the most ancient protein of EF-hands super family which is a group of proteins that binds calcium. It was shown that NCS-1 has many functions such as its capacity of inhibiting dopamine receptor D 2 desensitization and its capacity to activate phosphatidylinositol 4-kinase (PI4K). The dopamine and cAMP regulated phosphoprotein-32kDa (DARPP-32) has a central role in modulation of transduction of dopaminergic signaling. When phosphorylated at Threonine 34, DARPP-32 turns into a potent inhibitor of protein phosphatase-1 (PP-1) and consequently modulates

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13

Souza, Alessandra Hubner de. "Avaliação da atividade antinociceptiva espinal da toxina Ph1 isolada dp veneno da Phoneutria nigriventer em rodedores." Universidade Federal de Minas Gerais, 2008. http://hdl.handle.net/1843/SMOC-7P8HJ2.

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Calcium influx through voltage sensitive calcium channels (VSCCs) plays an important role on the nociceptive transmission in the dorsal horn of the spinal cord. The intrathecal administration of VSCCs blockers, such as -conotoxin-MVIIA (- CTx-MVIIA) has analgesic effect, but it narrows the therapeutic window, presenting many adverse effects. The Brazilian spider Phoneutria nigriventer venom contains a variety of substances with predominantly neurotoxic action, among them the Ph1 which was recently described as a potent neurotransmission blocker for interacting with N-type voltage sensiti

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14

Clarizia, Alessandra Duarte. "Avaliação do polimorfismo da metilenotetraidrofolato redutase (MTHFR) em amostras de câncer colorretal e câncer de mama." Universidade Federal de Minas Gerais, 2006. http://hdl.handle.net/1843/SMOC-6Y8FZ7.

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Epidemiologic studies suggest that the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism may modify the risk of both colorectal cancer (CRC) and breast cancer (BC). The C677T polymorphism is associated with the expression of a thermolabile enzyme with decreased activity that influences the levels of methyl-donor molecules. Considering that methylation abnormalities appear to be important in the pathogenesis of CRC, we have examined the relationship between the genotype at the MTHFR C677T polymorphism, hypermethylation of the promoter region of five genes (DAPK, MGMT, hMLH1,

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15

Bicalho, Maria Aparecida Camargos. "Estudo de polimorfismo do gene da triptofano hidroxilase 2 (TPH2) em idosos com depressão de inicio tardio." Universidade Federal de Minas Gerais, 2007. http://hdl.handle.net/1843/SMOC-7DRGHZ.

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A depressão é uma doença de elevada prevalência, que determina sofrimento, incapacidade e desordem social e eleva a taxa de mortalidade de doenças associadas, como a doença arterial coronariana. A população idosa é especialmente comprometida pela doença, apesar de ser frequentemente subdiagnosticada em decorrência das manifestações próprias nesta faixa etária. Nestes pacientes, ela se associa frequentemente à incapacidade cognitiva e outros comprometimentos funcionais. A depressão de início tardio é um subtipo especial de depressão, cujo início ocorre após os 60 anos de idade. Ela apresenta e

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16

Alvarenga, Emerson Angelo. "Perfil metabólico de vacas da raça Holandesa durante o período de transição, locais de colheita e métodos de análise de beta hidroxibutirato." Universidade Federal de Minas Gerais, 2013. http://hdl.handle.net/1843/SMOC-9E8FLA.

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Twelve dairy cows were collected between three weeks to parturition to three weeks after. They was in a free-stall in Inhaúma city, Minas Gerais estate between October and December of 2012. The metabolic profile was compounded with serum non-esterified fatty acids (AGNE), beta-hydroxybutyrate (BHBA), cholesterol (COL), total protein (TP), albumin (ALB), calcium, phosphorus, magnesium as well as the activity serum enzymes aspartate transaminase (AST) and lactate dehydrogenase (LDH). In a group of six animals, four sites were evaluated for blood collection - jugular, mammary and coccygeal veins

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17

Bastos, Ana Liz Ferreira. "Estudo da dinâmica populacional e das estratégias de manejo da população canina no município de Itabirito, MG, Brasil de 2007 a 2011." Universidade Federal de Minas Gerais, 2013. http://hdl.handle.net/1843/SMOC-9DWMBP.

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This paper aimed at studying the canine population dynamics and evaluate its population management strategies in Itabirito county, Minas Gerais State, from 2007 to 2011. Data were collected through two cross-sectional studies applied at intervals of one year, 10% of the canine population, randomly sampled systematically in all neighborhoods of the urban area, and by obtaining secondary data from the Zoonosis Service Control and the Department of animal protection in the county. The impact of population density in canine sterilization was performed by means of mathematical modeling. The results

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18

Gonçalves, Stefanne Aparecida. "Controle do reservatório canino para leishmaniose visceral, na regional noroeste de Belo Horizonte, Minas Gerais, 2006-2011." Universidade Federal de Minas Gerais, 2013. http://hdl.handle.net/1843/SMOC-9DWPFJ.

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Was conducted a descriptive study with the objective of to describe the occurrence of canine visceral leishmaniasis, in the Northwest Regional in Belo Horizonte, from 2006 to 2011. Data regarding with the canine control were obtained from the Municipal Secretariat of Health. From a total of 151.725 tests, 86.1% were negative, 7.4% were positive, 2,1% were undetermined and 3.8% were monitor. The expansion of the disease along the period was evident. There was an increase of the coverage of census surveys and a decrease in the tests requested by residents, followed by decreasing of the canine pr

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19

Araujo, Amanda Soriano. "Desenvolvimento de novas formulações de vacinas inativadas e de subunidades utilizando o parvovírus suíno como modelo." Universidade Federal de Minas Gerais, 2012. http://hdl.handle.net/1843/SMOC-9E3HPP.

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The objective of this work is to develop new formulations of inactivated and subunit vaccines using porcine parvovirus (PVS) as a model. Four adjuvant formulations have been developed, i) multiple emulsion, ii) microemulsion, iii) chitosan microspheres and iv) implants of chitosan. It have been developed a virus like particle (VLP-PVS) vaccine using baculovirus system. 1024 UHA of PVS suspension was used to produce the vaccines. The matches produced were tested for stability, safety, sterility and potency. The immune response was evaluated using vaccination of guinea pigs and the monitoring of

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Pires, Prhiscylla Sadanã. "Estudo patológico, padronização e uso da imuno-histoquímica em animais experimentalmente e naturalmente infectados com clostrídios histotóxicos." Universidade Federal de Minas Gerais, 2011. http://hdl.handle.net/1843/SMOC-9EJN79.

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An immunohistochemistry (IHC) was optimized to detect C. septicum, C. chauvoei, C. novyi type A, C. perfringens type A and C. sordellii using tissues obtained from guinea pigs experimentally infected with these strains. Furthermore, we established the etiologic diagnosis of myonecrosis in a retrospective study of samples from Mato Grosso do Sul (MS). Primary antibodies were obtained after repeated inoculations (days 0, 28, 49, 70 and 91) of rabbits with reference strains of Clostridium histotóxicos. Purification of immunoglobulins was performed using an affinity chromatography column of protei

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Araujo, Douglas Kiarelly Godoy de. "Avaliação de técnicas cirúrgicas para cistostomia em ovinos com obstrução uretral induzida." Universidade Federal de Minas Gerais, 2011. http://hdl.handle.net/1843/SMOC-9HKGWA.

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Laparotomy (G1), laparoscopy (G2), and transcutaneous approach (G3) for implantation of a Foley catheter in ram lambs with induced urethral obstruction were compared to determine the best option for small ruminants with obstructive urolithiasis. The 18 animals used were randomly allocated into the three groups described above. From each individual, the penis was exposed and the urethral process obstructed with 3-0 polycot for 12 hours. The determined surgical procedure was performed for tube cystostomy. If the bladder was teared during surgery, the procedure would then change to laparotomy aft

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Garro, Fabiana Leoncio. "Caracterização do complexo teníase-cisticercose bovina em São João Evangelista/MG." Universidade Federal de Minas Gerais, 2011. http://hdl.handle.net/1843/SMOC-9HKJ99.

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This study was carried out to determine the situation of human taeniasis and bovine cysticercosis in the city of São João Evangelista, located in Guanhães, Minas Gerais. Serum samples was collected from 339 cattle in 15 randomly selected farms to perform ELISA and Immunoblot serological tests in order to diagnose cysticercosis, using vesicular fluid antigen (LVcra) from Taenia crassiceps. A socioeconomic questionnaire was filled in each property for the analysis of the factors that favor the maintenance of the complex. Additionally, there was the diagnosis of human taeniasis verified by stool

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Dorneles, Elaine Maria Seles. "Avaliação da diversidade genética de isolados de Brucella abortus em um foco de brucelose." Universidade Federal de Minas Gerais, 2011. http://hdl.handle.net/1843/SMOC-9ENQHB.

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The purpose of this study was to evaluate the genetic diversity of isolates of B. abortus from a single outbreak of brucellosis in function of time and clinical specimen from which the isolate was obtained, and thus indirectly investigate the stability of the MLVA 16 markers. Two hundred and sixty-one clinical samples of cattle belonging to an outbreak of brucellosis were collected during 13 months, 161 samples of vaginal swabs and 100 milk samples, which were submitted to culture, biotyping, molecular identification and genotyping by MLVA 16. Nine B. abortus strains isolates obtained from vag

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Borges, Natalie Ferreira. "Estudo comparativo da placa em ponte associada ao pino intramedular e da placa de compressão dinâmica na fixação de osteotomia experimental em fêmur de coelhos (Oryctolagus cuniculus). Análises clínica, radiográfica, histológica e cintilográfica." Universidade Federal de Minas Gerais, 2011. http://hdl.handle.net/1843/SMOC-9ENQUY.

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The objectives were to benchmark and monitor the fracture healing of femoral osteotomy in rabbits after fixation with dynamic compression plate and bridge plate associated with intramedullary pin. Were used 14 New Zealand rabbits, four months old with mean weight of 3.5 pounds, from the Experimental Farm Professor Hélio Barbosa's Veterinary School of UFMG. The animals were randomly divided into two groups (I and II). All rabbits underwent osteotomy across the middle third of right femur. In the group I was made to fix the osteotomy with the bridge plate (BP) associated with intramedullary pin,

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Coura, Fernanda Morcatti. "Estudo longitudinal prospectivo da incidência de enteropatógenos em bezerras em uma propriedade leiteira." Universidade Federal de Minas Gerais, 2011. http://hdl.handle.net/1843/SMOC-9HKJNB.

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This study investigated the frequency of group A rotavirus (RV-A), bovine coronavirus (BCoV), Salmonella spp. and diarrheagenic Escherichia coli. Eight hundred and fifty fecal samples were collected from 67 calves at a farm in the city of Martinho Campos/MG. The animals were followed from birth to at least 60 days old. BCoV was detected by semi-nested RT-PCR and RV-A by polyacrylamide gel electrophoresis (PAGE). Virulence factors of Escherichia coli were identified by multiplex PCR. Salmonella spp. was identified by biochemical tests and serotyping of the strains. The first and second weeks of

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Magalhaes, Fernanda do Carmo. "Diagnóstico da situação da teníase e da cisticercose bovina no município de Salinas/MG, 2010." Universidade Federal de Minas Gerais, 2011. http://hdl.handle.net/1843/SMOC-9HMP75.

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The objective of this study was to evaluate the health situation of the taeniasis cysticercosis complex in the city of Salinas-MG, by estimating the prevalence of bovine cysticercosis and human taeniasis in rural properties and determine the health conditions and socio-economic of each property. We conducted a cross-sectional study involving properties located in the rural area, where 355 samples were collected from bovine blood, stool samples of all residents of farms and application of a questionnaire. Moreover, it was an epidemiological survey of taeniasis cases diagnosed in laboratories ac

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Drummond, Juliana Beaudette. "Estudo dos genes WNT4 E CTNNB1 na síndrome de MAYER-ROKITANSKY-KÜSTER-HAUSER." Universidade Federal de Minas Gerais, 2007. http://hdl.handle.net/1843/SMOC-733PBM.

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The Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is a congenital malformation of the female genital tract and is the second cause of primary amenorrhea, affecting one in every 5000 female live births. The genetic defect associated with the Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome has not been determined. Its elucidation would not only shed light up on the pathogenesis of the MRKH syndrome, but would greatly contribute to the general understanding of the genetic control of human fetal sexual development, specially the female sex, which has always been considered the default pathway. We

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Pinheiro, Ana Cristina do Nascimento. "Efeito das neurotoxinas da aranha phoneutra nigriventer na isquemia cerebral in vitro." Universidade Federal de Minas Gerais, 2008. http://hdl.handle.net/1843/SMOC-7EGGWM.

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The role of calcium channel blockers in ischemic conditions has been studied and described in literature. The PhTx3 fraction of the venom of Phoneutria nigriventer spider is a broad spectrum calcium channel blocker, which inhibits glutamate release and calcium uptake in synaptossomes. The PhTx3 fraction contains six isotoxins: Tx3-1 to Tx3-6. Some of these isotoxins block calcium channels type -P/Q, and other blocks the N-type calcium channels. With this action, these isotoxins inhibit calcium uptake and the release of neurotransmitters. The Tx3-3 and Tx3-4 toxins inhibit calcium channels typ

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Filho, Fernando Carbonari Santana. "Recusas de borrifação de imóveis e a ocorrência de casos humanos de leishmaniose visceral na regional Noroeste de Belo Horizonte, Minas Gerais,2006 a 2008." Universidade Federal de Minas Gerais, 2010. http://hdl.handle.net/1843/SMOC-9EJM2M.

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The purpose of this study was to characterize the refusal by the population to allow spraying of their houses in four regions of Belo Horizonte, in the period 2006 to 2008, and relate these denials with the emergence of human cases of visceral leishmaniasis in the same location and time. Chemical control vector is a measure of the control program of visceral leishmaniasis and it is based on the spraying of residual insecticides on the interior and exterior walls of houses. The right of refusal of the owner of the house is guaranteed by law, may agree to the spraying only internally or external

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Lasmar, Pedro Veloso Facury. "Avaliação clínica e parasitológica de animais inoculados com vacinas inativadas de Anaplasma marginale e desafiados experimentalmente." Universidade Federal de Minas Gerais, 2010. http://hdl.handle.net/1843/SMOC-9ENR9C.

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In the present work, inactivated vaccines of Anaplasma marginale were valued (vaccine containing 3 x 109 corpuscles of Anaplasma marginale + oil adjuvante, vaccine containing 3 x 109 corpuscles of Anaplasma marginale + culture supernatant and saponin as an adjuvant and vaccinates with culture supernatant + saponin together with a control group (saline solution + oil solution) in 20 calves (HPB) with six months of age, in front of experimental challenge with 3 x 105 corpuscles of Anaplasma marginale sample UFMG2 (sample without appendix, thought of rise pathogenicity). The method used for the e

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Drummond, Bruno Lapertosa. "Subfração PnTx 3-6 do veneno da aranha armadeira (Phoneutria nigriventer) no tratamento de ratos wistar (Rattus novergicus) submetidos ao trauma compressivo agudo à medula espinhal." Universidade Federal de Minas Gerais, 2010. http://hdl.handle.net/1843/SMOC-9HCQPQ.

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The aim of this study was to evaluate the effect of the PnTx3-6 sub fraction, derived from Phoneutria nigriventer toxin, on acute spinal trauma in Wistar rats. Eighteen male animals, approximately three months old, weighting an average of 350g were used. All animals underwent laminectomy (Group G1 negative control) on 12th thoracic vertebrae, and 12 of them (Groups G2 and G3) were also submitted to compressive spinal injury by a weight drop model (70g for five minutes) applying pressure directly over the duramater. After 30 minutes, treatment was administered to the traumatized animals by int

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Silva, Leandro de Araujo. "Taxa de gestação e mortalidade embrionária em receptoras de embriões produzidos in vitro, após sincronização do estro com diferentes protocolos hormonais." Universidade Federal de Minas Gerais, 2010. http://hdl.handle.net/1843/SMOC-9HDJDA.

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This study aimed to evaluate the influence of different factors on selection of recipients, pregnancy rates and embryonic mortality following transfer of in vitro produced embryos. It was evaluated 3,507 embryo transfers for recipients displaying natural or synchronized estrus using PGF or progesterone releasing intravaginal devices. Also, it was evaluated the stage of embryonic development, the synchronization between embryo stage and day of estrus of the recipient and the seasons of the year. The rate of selected recipients differed among treatments (p<0.05), 80.6%, 88.6% and 70.9% for natur

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Menezes, Fernanda Lusmara de. "Percepção dos produtores rurais da região de Sete Lagoas, MG, sobre o meio ambiente, 2008-2009." Universidade Federal de Minas Gerais, 2010. http://hdl.handle.net/1843/SMOC-9HDJWH.

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The intervention on the environment triggered by agricultural production has serious consequences to the health of individuals. This descriptive study has as its main objective to indentify the perception of farmers in relation to the environment. It was realized 68 interviews with dairy farmers of Regional Cooperative of Rural Producers of Sete Lagoas, Minas Gerais. The responses were evaluated for the frequencies in to software Epi Info 6.04. It was found that only 47% used some form of water treatment before consumption. The manure is applied directly on crops (19%). Among participants 40%

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Leite, Patricia Vieira Bossi. "Dinâmica da infestação, abordagem semiológica e tratamento das infestações por Rhabditis spp. e Raillietia spp. em bovinos Gir, Minas Gerais, 2010." Universidade Federal de Minas Gerais, 2010. http://hdl.handle.net/1843/SMOC-9HDMW7.

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The study took place in Teófilo Otoni municipality, MG, Brazil from august 2008 to august 2009. Experiment A evaluated dynamic of the parasitic infection caused by the nematode Rhabditis spp. and the mite Raillietia spp. It were used sixty four animals of a dairy herd, Gir breed, males and females, age ranging from 04 to 33 months. Every three months, material of the external auditory canal of all the animals was collected by flushing the right ear and at the same time the left ear was swabbed in order to observe the presence of parasites. The frequency of total positives for Rhabditis spp was

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Drummond, Alice Ferreira. "Caracterização de carne de sol no município de Salinas/Minas Gerais." Universidade Federal de Minas Gerais, 2010. http://hdl.handle.net/1843/SMOC-9HDNBS.

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The Carne de Sol is product produced and widely consumed in regions of semi-arid region of Brazil. Due to its historical importance, socio-economic, cultural and health was held in this study to evaluate the physico-chemical, microbiological and production of this product sold in Salinas / MG. We analyzed 40 samples of meat collected from the Sun to retail establishments located in the city of Salinas / MG. The profile of production and processing, were obtained through visits and administering a questionnaire. The results showed that the physical chemistry of Carne de Sol showed values close

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Júnior, Custódio Antônio Carvalho. "Estudo andrológico e ultrassonagráfico em carneiros durante o curso de infecção experimental por Brucella Ovis." Universidade Federal de Minas Gerais, 2010. http://hdl.handle.net/1843/SMOC-9HEQNA.

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Brucella ovis is considered the most important infectious cause of reproductive disorders in sheep. The disease is characterized by epididymitis, sub-fertility and infertility in rams and occasionally abortion in ewes. Although clinical aspects of the disease have been studied, changes in the parenchyma of affected organs have only been evaluated by histology, and the correlations between clinical signs and seminal features of the affected rams have been described mostly in naturally infected rams, when it is not possible to assess the time course of infection. Moreover, real-time ultrasonogra

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Assis, Bianca Seridan de. "Efeito de Lactobacillus rhamnosus e de Lactococcus lactis isolados de queijo de coalho na viabilidade e produção de enterotoxina B por staphylococcus aureus FRI-S6 em queijo." Universidade Federal de Minas Gerais, 2010. http://hdl.handle.net/1843/SMOC-9HHJJX.

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Homemade cheese, which consumption is widely known through the world, is frequently attached to food borne intoxication break outs. The most prevalent pathogen in these cases is Staphylococcus aureus, responsible for the majority of cases of mammary infection in cows and transported by food manipulation. At the present study, S. aureus was inoculated in sterile lab produced cheese among to Lactobacillus rhamnosus and Lactococcus lactis, in real concentrations, as found in home made cheese. Analysing enumeration values, the ALB did not have the power of reduce S. aureus counts, but showed evide

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Carmo, Filipe Borges do. "Perfil soroepidemiológico da linfadenite caseosa em caprinos no Ceará, Brasil." Universidade Federal de Minas Gerais, 2010. http://hdl.handle.net/1843/SMOC-9HHJTP.

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The present work is the first seroepidemiological study on caseous lymphadenitis in goat herds in the state of Ceará, Brazil. Serum samples were collected from 3239 goats from 127 rural properties from 29 municipals districts in 1997. In each property was applied a questionnaire comprehending information about the management and the animals. The seroprevalence was established in the results of an indirect enzyme-linked immunosorbent assay (ELISA) that detects anti-bodies against Corynebacterium pseudotuberculosis. Prevalence values were calculated using the software WinEpiscope®2.0 and 26,2% o

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Silva, Teane Milagres Augusto da. "Identificação de genes envolvidos na patogênese de Brucella ovis em modelo murino." Universidade Federal de Minas Gerais, 2010. http://hdl.handle.net/1843/SMOC-9HJMZW.

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Brucella ovis is one of the main causes of reproductive failure in sheep. Due to the scarcity of studies of B. ovis infection in the mouse, a murine model of infection was developed in this study. BALB/c or C57BL/6 male mice were inoculated intraperitoneally with 106CFU of B. ovis and fragments of the spleen, liver and genital tract were collected for bacteriology, histopathology and immunohistochemistry. Both mice strains had similar kinetics of B. ovis infection and developed microgranulomas in the liver and spleen, with low numbers of intralesional immune-stained B. ovis. There was minimal

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Bastianetto, Eduardo. "Infecção por Eimeria spp. em búfalos jovens e avaliação de esquemas terapêuticos metafiláticos." Universidade Federal de Minas Gerais, 2010. http://hdl.handle.net/1843/SMOC-9ENPKV.

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Buffalo (Bubalus bubalis) breeding is nowadays a growing activity in several continents not only for its best fitting to tropical conditions but also for its milk and meat production demands. Physiological features of the bubaline species combined with handling practices in use to raise cattle propitiate young animal infection by parasites of gender Eimeria. The impact of the infection by parasites on buffaloes is acknowledged worldwide wherever eimeriosis in young animals is prominent for its high morbidity and mortality. For the analysis of the circumstances involved in the development of th

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Guimaraes, Alessandro de Sa. "Epidemiologia da linfadenite caseosa ovina no estado de Minas Gerais, Brasil." Universidade Federal de Minas Gerais, 2009. http://hdl.handle.net/1843/SMOC-9HCPA4.

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Caseous Lymphadenitis (CL) is a diesease of worldwide occurrence caused by Corynebacterium pseudotuberculosis. It inflicts considerable economic losses due to decreased wool, meat, and milk production, impaired reproduction efficiency, and carcass and leather condemnation due to abscesses. A review of the literature concerning CL was made and incorporated into this thesis. The lack of information about the serological status of sheep herds in Minas Gerais, Brazil, motivated the serological survey herein described. Ovine sera (n=642) collected from 97 properties in the State of Minas Gerais, Br

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Leal, Barbara Simoes Santos. "Detecção de zona híbrida entre Cattleya coccinea e C. brevipedunculata (Orchidaceae) no Parque Estadual do Ibitipoca, Minas Gerais, utilizando microssatélites e análise morfométrica." Universidade Federal de Minas Gerais, 2013. http://hdl.handle.net/1843/SMOC-99MPGV.

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Although the expression of morphological traits in hybrid is unpredictable, often resulting in a mosaic of parental, intermediate, and new characters, many natural hybrids of Orchidaceae have been reported only through the observation of intermediate phenotypes to its putative parental. Molecular markers have been shown to be a good tool to test such morphological hypotheses and to characterize the architecture of natural hybrid zones in plants, including in Orchidaceae. In this study, we used multivariate morphometric analyses of 24 floral and vegetative characters and molecular genetic analy

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Costa, Frederico Augusto de Alcântra. "Molecular epidemiology and development of vaccines against emerging pathogens for Brazilian fish farming: Streptococcus dysgalactiae and Weissella ceti." Universidade Federal de Minas Gerais, 2013. http://hdl.handle.net/1843/SMOC-9FFHUT.

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Streptococcus dysgalactiae and Weissella ceti have been considered emergent pathogens for Brazilian Nile tilapia (Oreochromis niloticus) and rainbow trout (Onchorhynchus mykiss) farming, respectively. Both diseases cause great economic losses in fish farms. Disease prevention by vaccination is a fundamental method for pathogen control in aquaculture. The aims of this study were to evaluate the genetic diversity of S. dysgalactiae and W. ceti strains isolated from distinct geographic origins and to develop efficient vaccines against these pathogens. Different methods (REP-PCR, ERIC-PCR and PFGE

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Uribe, Jose Azael Zambrano. "Desenvolvimento de um modelo animal para avaliação da eficiência de vacinas contra gangrena gasosa causada por Clostridium perfringens tipo A." Universidade Federal de Minas Gerais, 2013. http://hdl.handle.net/1843/SMOC-9FVPJM.

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The myonecroses infections caused by Clostridium perfringens type A are characterized by rapid course and high mortality, not knowing the impact it has on both national and global livestock. The objective of the present work was to establish a model of experimental induction of gas gangrene by inoculation of vegetative bacteria Clostridium perfringens type A, as well as to assess the efficacy of three experimental vaccines (toxoid, bacterin, toxoid + bacterin) and another of commercial source. Were used 98 albino guinea pigs (Cavia porcellus) of the lineage "Inglês short ear", males, weighing

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Moreira, Tiago Facury. "Perfil metabólico de vacas leiteiras no período de transição em sistema semi-intensivo em Minas Gerais no verão e no inverno." Universidade Federal de Minas Gerais, 2013. http://hdl.handle.net/1843/SMOC-9G7NWB.

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In this study, it was evaluated the metabolic profile of dairy cows during the transition period into two seasons, summer and winter. It was used in every season 31 crossbred girolando cowswith two or more calving, totaling 62 cows. During the summer, the animals remained on pasture and were supplemented with corn silage and concentrate in the trough. In winter, corn silage and concentrate was given as much tomeet nutritional requirements. It was made a total of 11 blood samples from each animal according to the following protocol: four samples antepartum spaced weekly, at birth and at 2, 5, 1

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Lopes, Eliane Goncalves Paiva. "Dinâmica da transmissão da leishmaniose visceral em uma coorte de cães em Juatuba-MG, de 2010 a 2011." Universidade Federal de Minas Gerais, 2013. http://hdl.handle.net/1843/SMOC-9GXHHT.

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A prospective cohort study of canine visceral leishmaniasis (CVL) was carried out from 2010 to 2011 in Juatuba Minas Gerais State in order to know the dynamic of the disease transmission, its incidence and factors associated to Leishmania infantum infection as well. An observational and prospective cohort facade study was made by serologic analyses of dogs which were selected at random throughout the county. Each semester, the results negative and undetermined at sera Indirect Immunofluorescence (IFA) were checked. A semi-structured questionnaire was applied to the owners of the dogs to eval

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Miranda, Fernanda Guimaraes. "Linha Morgan e sua relação com a displasia coxofemoral em cães." Universidade Federal de Minas Gerais, 2013. http://hdl.handle.net/1843/SMOC-9H6QE8.

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It has been evaluated 160 (four of each dog) hip joints radiographs of 40 different breeds of dogs (25 females and 15 males) from the metropolitan area of Belo Horizonte, Minas Gerais, Brazil.The radiographs of each animal were obtained at two different stages: stage 1 (mean 7.23 months) and stage 2 (mean 14.25 months). The conventional radiographic method (CRM) and the radiographic distraction method (RDM) were used, carried out in both stages. In CRM, the relationship between the femoral head and acetabulum through the Norberg angle (NA) was quantificated. The angle of inclination (AI) was m

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Stehling, Monica Maria Campolina Teixeira. "Estudo sobre riscos ocupacionais, biológicos e químicos, em laboratórios de uma universidade pública brasileira, 2012-2013." Universidade Federal de Minas Gerais, 2013. http://hdl.handle.net/1843/SMOC-9HCJ5D.

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Observational, transversal, analytic, qualitative and quantitative study. The community target of our research was composed by researchers, teachers, graduation students, post-graduation students, internships and employees. On the first stage of the thesis we intended to check the factor related to the occurrence of accidents, through a survey about occupational risks, biological and chemical, questioning about Personal Protection Equipment, Biosecurity Handbooks, Customer Service to the Victims and the Standard Operational Procedure. We tried to identify the victims through these risks in thr

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Varon, Jessica Alejandra Castro. "Biocerâmica de fosfato de cálcio nano-estruturado micro-macro porosa em grânulos de absorção rápida no preenchimento de defeito crítico em radio de coelhos (Oryctolagus cuniculus)." Universidade Federal de Minas Gerais, 2013. http://hdl.handle.net/1843/SMOC-9HXP2S.

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The objective of this study was to evaluate by radiography , histology and bone densitometry the effect of HA / TCP granules for rapid absorption in critical bone defect in radio rabbits ( Oryctolagus cuniculus ) . 35 rabbits were used in which a critical defect was performed on left and right radios . The animals were divided into GI , GII autograft and HA / TCP granules for rapid absorption . Radiographic examinations were made before surgery, immediately after the eighth , 15, 30 , 45, 60 , 90 and 120 days. At the end of each period, the animals were euthanized by anesthetic overdose and ra

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Carvalho, Julia Gomes de. "Influência do volume de sucedâneo ingerido e do tratamento com antibiótico e anti-inflamatório sobre o perfil bioquímico, eletrolítico e a etiologia da diarréia em bezerros." Universidade Federal de Minas Gerais, 2013. http://hdl.handle.net/1843/SMOC-9J9GNA.

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This study was divided into two experiments. The first experiment evaluated the biochemical profile of newborn calves feeding different volumes of milk replacer during diarrhea and describes the major pathogens in fecal samples from diarrhea in newborn calves through a longitudinal study. Group 1 was offered 4 liters of milk replacer and group 2, 6 liters, this tended to have higher consumption during diarrhea compared to group 1. Group 2 had higher levels (p <0.05) of blood concentrations of sodium and potassium during diarrhea compared to group 1 and lower levels of urea, creatinine and albu

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