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1
Rocha, Carols A. (Carlos Andres Rocha Penagos). "SMPL : a network architecture for collaborative distributed services." Thesis, Massachusetts Institute of Technology, 2005. http://hdl.handle.net/1721.1/33889.
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Thesis (S.M.)--Massachusetts Institute of Technology, School of Architecture and Planning, Program in Media Arts and Sciences, 2005.<br>Includes bibliographical references (p. 85-89).<br>This thesis proposes a network architecture, called SMPL, for the design and development of collaboration-oriented, distributed applications over the Internet. The goal of SMPL is to enable the development of applications that easily integrate the capabilities of different types of computing resources, software platforms, and data repositories across the Internet transcending the level of a single device. SMPL proposes a new abstraction of the Internet as a network composed of services, resources, and capabilities instead of just machines. The SMPL architecture distributes resources through a peer-to-peer network of service providers. The design of SMPL encourages developers to add value to the system by facilitating the creation of new functionalities based upon compositions of the existing ones.<br>Carlos A. Rocha.<br>S.M.
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Holden, James Anthony, and jamesholden@netspace net au. "Vaccination Strategies for the Prevention of Swine Dysentery." RMIT University. Applied Sciences, 2006. http://adt.lib.rmit.edu.au/adt/public/adt-VIT20070112.122102.
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The SmpA outer membrane lipoprotein of B. hyodysenteriae has several characteristics that indicate the potential to protect against swine dysentery (SD). It localises to the outer membrane and antibodies directed against SmpA can prevent the growth of B. hyodysenteriae in vitro. There is some variation observed in the distribution and expression of the SmpA lipoprotein, suggesting that vaccination with SmpA may not provide protection against challenge with a heterologous B. hyodysenteriae strain. This study has characterised the variation at the smpA locus, and in the process has identified a novel gene, smpB. There is very low similarity between smpB and smpA, with the exception of an identical lipoprotein signal sequence. This suggests that SmpB may be translocated to the outer membrane of B. hyodysenteriae in a similar fashion to SmpA. The results described in this thesis indicate that strains of B. hyodysenteriae harbour either smpA or smpB, but not both, explaining the earlier results of Turner et al. (1991). The presumed outer membrane location of SmpB lead to further investigations into its potential to protect mice from infection with B. hyodysenteriae. Swine Dysentery is a inflammatory disease of the swine colon. Therefore it is believed that a mucosal immune response may provide increased protection against challenge. In this study, vaccination of mice with recombinant SmpB elicited high levels of serum antibodies, induced the production of Interleukin-4 producing T lymphocytes and decreased the observed histological effects after challenge with virulent B. hyodysenteriae. In efforts to increase the protected conferred by vaccination with SmpB, recombinant Salmonella typhimurium STM-1 vaccines were created to express SmpB or deliver DNA vaccines encoding SmpB. Vaccination with these recombinant Salmonella vectors did not induce a measurable SmpB specific immune response. Macrophage survival and plasmid stability studies indicated that this was due to instability of the expression plasmids in STM-1. Although SmpB will only ever protect against strains of B. hyodysenteriae harbouring smpB, these results indicate that with further research, SmpB (and SmpA) may contribute to protection from SD. Toxin production is an important aspect of the pathogenesis of many pathogenic bacteria. Vaccination with attenuated toxins is commonly used to prevent disease. In this study, the B. hyodysenteriae â-haemolysin HlyA was used to vaccinate mice to determine the protection induced after challenge. Vaccination of mice with recombinant HlyA induced significant levels of serum antibodies and lowered the observed pathological effects after challenge of vaccinated mice with virulent B. hyodysenteriae. In an attempt to increase the mucosal immune response and therefore the protection afforded after vaccination with HlyA, recombinant S. typhimurium STM-1 strains were created to express HlyA or deliver DNA vaccines encoding HlyA. Similar to the recombinant STM-1 vaccines expressing SmpB, a HlyA specific immune response was not observed by ELISA or ELISPOT analysis. Plasmid stability trials revealed that the inability to induce a detectable HlyA specific immune response by recombinant STM-1 vaccination may be due to ins tability of the plasmids. Outer membrane proteins are often important components of vaccines against bacterial and viral pathogens. Considering the variation observed in the smpA locus in this study resulting in the identification of smpB, further investigation into the distribution and conservation of outer membrane encoding genes in B. hyodysenteriae strains was undertaken. In particular, the blpAEFG, vspABCD and vspEFGH clusters were analysed for their distribution. It was demonstrated that genes that are B. hyodysenteriae specific (vspABCD and vspEFGH) displayed higher levels of polymorphism than those that are distributed amongst non-pathogenic species, such as B. innocens (which contains blpAEFG). This suggests that the variation in the vspABCD and vspEFGH clusters amongst B. hyodysenteriae strains may be a result of the exposure to the host immune system. Further investigation was undertaken by PFGE analysis and 2D-gel electrophoresis, to analyse genomic and proteomic variation at a global level. Although strains of B. hyodyse nteriae produced several different electrophoretic types (ET) upon PFGE analysis, only limited correlation between the PFGE ET, the polymorphisms in vspABCD and vspEFGH and the presence of smpA/smpB were observed. 2D-gel electrophoresis analysis of outer membrane preparations of two B. hyodysenteriae strain revealed several distinct differences in the outer membrane between B. hyodysenteriae strains. The observed differences in the proteins contained in the outer membrane of B. hyodysenteriae is important for vaccine design, as the induction of cross protection between strains of B. hyodysenteriae is essential for a effective vaccine.
3
Dallacosta, Adriana. "Modelo SMIL I-HTSPN." Florianópolis, SC, 2000. http://repositorio.ufsc.br/xmlui/handle/123456789/78839.
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Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico.<br>Made available in DSpace on 2012-10-17T19:58:29Z (GMT). No. of bitstreams: 0Bitstream added on 2014-09-25T17:31:29Z : No. of bitstreams: 1
172951.pdf: 3141863 bytes, checksum: 4d7800cdc05b74a26dd0892b62c67631 (MD5)<br>A linguagem SMIL tem sido projetada de maneira a facilitar a autoria de apresentações multimídia na Web. Com um editor de texto ela permite definir os componentes de documentos multimídia como texto, imagens, áudio e vídeo na forma de URIs e escalona suas apresentações em paralelo ou em seqüência. A desvantagem é que a manipulação da noção de tempo na forma textual é difícil manipular e modificar. Ao contrário, o modelo I-HTSPN facilita a autoria de apresentações multimídia por ser um sistema gráfico e, além disso, por ser um método formal, permite a especificação e análise do documento, para posterior tradução para o código SMIL Boston. A especificação gráfica de documentos SMIL será obtida graças a uma nova interpretação do modelo I-HTSPN voltada para a especificação, análise e geração de código SMIL Boston. Esta nova interpretação se chama SMIL I-HTSPN e herdará todas as técnicas de análise do HTSPN.
4
Ohlenroth, Matthias, and Thomas Radke. "Linux SMP." Universitätsbibliothek Chemnitz, 1998. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-199800243.
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Liljeqvist, Björn. "StockholmsOperan, Galärvarvet : En smal sak." Thesis, KTH, Arkitektur, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-37316.
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Galärvarvet är på många sätt en utmärkt plats för en ny och framträdande kulturbyggnad i Stockholm. Samtidigt utgöt operans komplexa och omfattande program en stor utmaning. I detta projekt löses konflikten mellan program och plats meddels en långsmal byggnad som bevarar naturvärden och rörelsemönster.<br>Galarvarvet is in many ways an great site for a new and prominent cultural building in Stockholm. At the same time the complexity and size of the program of an opera poses a great challenge. In this project the conflict between program and site is solved with a stretched out building that preserves environmental values and movements.
6
Laaksonen, Mikael. "A reliable SMPP implementation in Erlang." Thesis, Uppsala universitet, Institutionen för informationsteknologi, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-204894.
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Software failure is one of the main problems in computer systems. Especially in systems with demand for high availability, such as telecom systems. SMPP is a protocol for sending short messages between entities in the telecom network. This thesis describes the design and implementation of a highly fault tolerant and reliable SMPP server and client. The implementation is done in Erlang, a language that was designed for fault tolerance. After testing the fault tolerance, the developed software has been integrated into telecommunication systems in commercial use at Mobile Arts.
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Austin, Ty (Roydrick Tyrone). "Makivism design : Social Media Participatory Design (SMPD)." Thesis, Massachusetts Institute of Technology, 2018. http://hdl.handle.net/1721.1/118500.
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Thesis: S.M. in Architecture Studies, Massachusetts Institute of Technology, Department of Architecture, 2018.<br>Cataloged from PDF version of thesis. "June 2018."<br>Includes bibliographical references (page 60).<br>We live in a world today where instantaneous transparency is the rule of thumb. Social media platforms such as Facebook or Linkedin have become the primary modes of communication and connectivity amongst professional and personal circles. Building Information Modeling, or BIM, is a 3D parametric modeling software. BIM visually assists architecture and engineering design teams remotely collaborate, innovate, and connect instantaneously with colleagues clients in more productive ways to create efficient construction projects. However, BIM's strengths in efficient transparency are often not extended to the principal stakeholders of any project: the community. This thesis will examine an intersectional interest known as Social Media Participatory Design (SMPD) or Makivism Design. SMPD is the integration of both 3D parametric modeling with social media. Network platforms, such as Facebook or Linkedin, are the primary modes of communication and connectivity amongst design professionals and community leaders today. By implementing SMPD into the built environment sector, community stakeholders can attain instantaneous access into the design process of a project through their favorite social media app. The primary research objective of this thesis is examine whether SMPD provides the designer, or user, the knowledge and communication they need to make the informed, transparent and inclusive design making decisions needed to collaborate on community-based projects. We will determine whether SMPD has the potential to empower those who feel marginalized and demand designers and clients alike to be more inclusive.<br>by Ty Austin.<br>S.M. in Architecture Studies
8
Medeiros, Gean Cardoso de. "Uma modelagem gráfica para a linguagem SMIL." Florianópolis, SC, 2002. http://repositorio.ufsc.br/xmlui/handle/123456789/83706.
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Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Ciência da Computação.<br>Made available in DSpace on 2012-10-20T02:35:25Z (GMT). No. of bitstreams: 0<br>A linguagem SMIL 2.0 (Synchronized Multimedia Integration Language) é considerada uma linguagem relativamente fácil para o aprendizado e desenvolvimento de apresentações multimídia na Web, principalmente devido ao fato de ter herdado muitas das características da linguagem HTML. Contudo, quando da construção de apresentações multimídia que necessitam de um maior refinamento nas questões relacionadas ao tempo, essa torna-se complexa, pelo fato do usuário não possuir um modelo gráfico que lhe proporcione uma visão clara, objetiva e simples do comportamento temporal dos objetos multimídia inseridos na apresentação, tendo esse que recorrer a programação textual tradicional, tornando-se esse fato uma barreira aos usuários menos experientes em programação. Esta dissertação, teve como objetivo desenvolver um modelo gráfico de mais alto nível, que permite ao autor especificar de forma mais clara e objetiva a sincronização entre os objetos multimídia envolvidos na autoria. O modelo proposto é modelo gráfico ADS, o qual visa simplificar a construção de apresentações SMIL2.0, possibilitando ao autor ter visão clara, objetiva e simples com relações a questões temporais, a qual é o foco principal do modelo.
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Sulasalmi, Kristian, and Olof Olsson. "MoPho -enkla lösningar för SMS och MMS." Thesis, Blekinge Tekniska Högskola, Sektionen för teknokultur, humaniora och samhällsbyggnad, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:bth-2816.
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Our project is divided into two parts, one production and written report. The main focus was the production part, were we used PHP to create simple solution for handling SMS and MMS with direct communication with the mobile operator server. We communicate with sockets and can handle CIMD2 and MM7 protocol. To get our components easy to use we have created two classes to handle SMS and MMS. To demonstrate our technical platform we created a website were you can create an account. With the account you can send pictures and other files via MMS and publish them for all to see or you can keep them private. The written report focused on describing the MMS technique there by getting a good overview.<br>Vår produktion består av två moment, en produktions del och en skriftlig del. Tyngden ligger på vår produktion där vi med verktyget PHP skapat enkla lösningar för att hantera SMS och MMS direkt mot operatörernas servrar. Vi kommunicerar via sockets och kan hantera protokollen CIMD2 och MM7, för att användaren skall kunna använda vår teknik på ett så enkelt sätt som möjligt har vi skapat två klasser som på ett simpelt sätt skall kunna ta emot och skicka data. För att demonstrera vår tekniska produkt har vi skapat en webbsida där man kan skaffa sig ett eget konto. Med detta konto kan man skicka bilder och andra filer via MMS till webbsidan för att sedan publicera dem för allmänheten eller behålla dem som privata bilder/filer. Vår skriftliga del gick ut på att beskriva hur MMS tekniken fungerar och på så sätt få ett bättre grepp om teknikerna.<br>Detta är en reflektionsdel till en digital medieproduktion. Olof Olsson (borsna@gmail.com) 070-4767308 Kristian Sulasalmi (savve@savve.se)070-9150870
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Huang, Beilei. "Design and implementation of a SMIL-based TeleLearning system." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape8/PQDD_0002/MQ46585.pdf.
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Chew, W. M. "Optimum electromagnetic design for wound components in SMPS applications." Thesis, University of Bath, 1989. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.328339.
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Ardern, Hazel Alison. "The regulation of hepatic lipoprotein metabolism in the St Thomas' mixed hyperlipidaemic rabbit." Thesis, University of Glasgow, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.323855.
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Schmollinger, Martin. "Designing parallel algorithms for SMP clusters." [S.l. : s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=969343841.
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Puttmann, John Paul. "Spatially Targeted Activation of a SMP." University of Dayton / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=dayton1525166147319011.
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Kolář, Jan. "Motivace pracovníků ve firmě SMP CZ." Master's thesis, Vysoká škola ekonomická v Praze, 2011. http://www.nusl.cz/ntk/nusl-81623.
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The aim of this master thesis is an analysis of a motivation system in SMP CZ. The first part defines the way of a research and describes used methods. The second part focuses on theoretical knowledge, which is crucial for understanding of motivation. The biggest part is devoted to actual research of a job satisfaction of employees. In this context, possible solutions and perspectives for future development are suggested.
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Macedo, Marcos Roberto. "MHEG-5/SMIL: um ambiente de integração entre os padrões." Universidade Federal de São Carlos, 1999. https://repositorio.ufscar.br/handle/ufscar/357.
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Previous issue date: 1999-01-02<br>This work presents an integration environment between the standards MHEG-5
and SMIL. The MHEG-5 standard defines the syntax and the semantics of a group of
objects which can be used for interoperability of multimedia applications among
platforms with minimal resources. On the other hand, the SMIL standard provides
synchronized media in the Web documents. In order to integrate the two standards two
translators were developed. With this integration the multimedia applications can be
presented either in a Web environment, using SMIL, or in authoring tools following the
MHEG-5 standard. A rule database was developed to carry out the translations; which
has as an objective to store the translating rules between the standards allowing for
dynamism in the translation process. As a test database for the translations a
Multimedia Object Server multimedia database was used in the AMOM project, where
a connection module was developed between these database an the Web
environment. This work has also involved the proposal of an environment which
integrates the SOMm and the Web, whose title is MAW (Multimedia Application
WebBuilder).<br>Este trabalho apresenta um ambiente de integração entre os padrões: MHEG-5
e SMIL. O padrão MHEG-5 define a sintaxe e a semântica de um conjunto de objetos
que podem ser utilizados para interoperabilidade de aplicações multimídia entre
plataformas com recursos mínimos. Já o padrão SMIL disponibiliza sincronismo de
mídias nos documentos Web. Para integrar esses dois padrões foram desenvolvidos
dois conversores. Com essa integração, as aplicações multimídia podem ser
apresentadas tanto no ambiente Web, usando SMIL, como em ferramentas de autoria
segundo o padrão MHEG-5. Para realizar as conversões foi desenvolvida uma base
de regras, que tem como objetivo, armazenar as regras de conversões entre os
padrões, possibilitando que haja dinamismo no processo de conversão. Como base de
teste para as conversões, foi utilizado o banco de dados multimídia do Servidor de
Objetos Multimídia (SOMm) do projeto AMOM, aonde foi desenvolvido um módulo de
conexão entre esse banco de dados e o ambiente Web. Este trabalho também
envolveu a proposta de um ambiente que integra, o SOMm e a Web, cujo título é
MAW (Multimedia Application WebBuilder).
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SILVA, HERON VILELA DE OLIVEIRA E. "X-SMIL: IMPROVING REUSE AND EXPRESSIVENESS IN HYPERMEDIA AUTHORING LANGUAGES." PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2005. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=6950@1.
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PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO<br>FUNDO SETORIAL PARA DESENV. TECNOLÓGICO DAS TELECOMUNICAÇÕES<br>Este trabalho está inserido no contexto de ambientes de
autoria e execução
hipermídia, sendo as linguagens declarativas para autoria
de documentos o seu
foco principal. Tendo-se como objetivo aumentar a
expressividade e o reuso na
especificação de documentos hipermídia, este trabalho
introduz as linguagens XSMIL
e NCL - Nested Context Language - versão 2.1. Utilizando-
se o conceito de
templates, X-SMIL permite a definição de novas semânticas
para composições
SMIL, além dos tradicionais elementos seq, par e excl.
Templates, em X-SMIL,
são especificados em um perfil de XTemplate, que estende a
idéia original da
linguagem XTemplate de NCL. Com base nas novas facilidades
para definição de
templates, esse perfil foi usado para especificar a
linguagem NCL 2.1. X-SMIL
também permite a especificação de conectores hipermídia,
tratando relações
hipermídia como entidades de primeira classe -
funcionalidade incorporada em XSMIL
pelo uso do módulo XConnector de NCL. Outro objetivo deste
trabalho é o
de apresentar um framework para o processamento de
documentos XML.
Utilizando-se esse framework, diversos compiladores foram
implementados, o
que possibilitou, entre outras funcionalidades, a
conversão de documentos NCL
em especificações SMIL ou X-SMIL e vice-versa.<br>This work is related to hypermedia authoring and execution
environments,
and its main focus is declarative document authoring.
Aiming at improving the
expressiveness and reuse in the specification of
hypermedia documents, this work
introduces the hypermedia authoring languages X-SMIL and
NCL - Nested
Context Language - version 2.1. Exploiting the concept of
templates, X-SMIL
allows the definition of new semantics for SMIL
compositions, besides its usual
seq, par and excl elements. X-SMIL templates are specified
using an XTemplate
profile, which extends the original idea of the NCL
XTemplate language.
Bringing new facilities for template definitions, this new
profile is used to further
improve the NCL language. X-SMIL also offers support for
handling hypermedia
relations as first-class entities, through the use of
hypermedia connectors - brought
to X-SMIL via the NCL XConnector module. Another important
goal of this work
is to present a framework to facilitate the development of
XML documents
parsing and processing tools. Based on this framework,
several compilers were
implemented, permitting, among other features, the
conversion of NCL
documents into SMIL or X-SMIL specifications and vice-
versa.
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Neumann, Andreas. "Parsing and querying XML documents in SML." [S.l. : s.n.], 2000. http://deposit.ddb.de/cgi-bin/dokserv?idn=961036249.
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Martin, Michael Paul. "Performance measurement in the RAMP SMP facility." Thesis, Monterey, California. Naval Postgraduate School, 1989. http://hdl.handle.net/10945/26157.
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Yano, Thaise. "Mutation Testing Study in SML functional programs." Universidade de São Paulo, 2004. http://www.teses.usp.br/teses/disponiveis/55/55134/tde-08122014-104828/.
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Functional programming languages, such as SML (Standard Meta Language), Haskell and Lisp, focus on rules and matching of patterns, in contrast to procedural languages in which programs are written as a sequence of instructions. Programs in functional languages may have errors due to the misunderstanding of their properties. Testing is one of the essential activities to identify these errors and to guarantee the quality of the product under development. However, there are few initiatives and tools to support the testing of functional programs. Moreover, an important issue that is often not taken into consideration in this context is to provide a means to quantify the test activity. In this work, we establish mechanisms to investigate the aplicability of Mutation Testing for testing functional programs, written in SML. Mutation Testing is a test criterion that allows to evaluate the quality of a test set and to guide the generation of test sets. The existence of a tool to support this criterion is essential due to the large amount of information related to its application. The web tool PROTEUM/SML, developed with the aim of applying the Mutation Testing to SML, implements the mutation operators defined in this work. An example is provided to illustrate the concepts and PROTEUM/SML tool.<br>Ao contrário das linguagens procedimentais, em que os programas são escritos como uma sequência de instruções, as linguagens de programação funcional, tais como SML (Standard Meta Language), Haskell e Lisp, enfatizam regras e casamento de padrões. Os programas em linguagens funcionais podem conter erros pela falta de entendimento de suas propriedades. Assim, a atividade de teste é de grande importância na identificação desses erros, podendo fornecer evidências da qualidade do produto em teste. No entanto, existem poucas iniciativas para o teste de programas funcionais bem como no desenvolvimento de ferramentas de apoio a essa atividade. Além disso, os trabalhos existentes não possuem uma medida de cobertura da atividade de teste. Assim, motiva-se a investigação de novas formas de se realizarem testes em programas funcionais. Um critério de teste que fornece uma maneira de auxiliar na geração e na avaliação de um conjunto de casos de teste é o Teste de Mutação. Neste trabalho, estabelecem-se subsídios para a investigação da aplicabilidade do Teste de Mutação para o teste programas funcionais, escritos em SML. Devido ao grande volume de informações que estão envolvidas na aplicação do Teste de Mutação, é essencial a existência de ferramentas de apoio para o uso desse critério. A fim de viabilizar a aplicação do Teste de Mutação para SML, foi desenvolvida a ferramenta web PROTEUM/SML, que implementa os operadores de mutação definidos neste trabalho. Um exemplo é fornecido para ilustrar os conceitos e a ferramenta PROTEUM/SML.
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Rexby, Mattias. "SUPERVISED MACHINE LEARNING (SML) IN SIMULATED ENVIRONMENTS." Thesis, Mälardalens högskola, Akademin för innovation, design och teknik, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-54698.
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Artificial intelligence has made a big impact on the world in recent years, and more knowledge inthe subject seems to be of vital importance as the possibilities seems endless. Is it possible to teacha computer to drive a car in a virtual environment, by training a neural network to act intelligentlythrough the usage of supervised machine learning? With less than 2 hours of data collected whenpersonally driving the car, I show that yes, it is indeed possible. This is done by applying thetechniques of supervised machine learning combined in conjunction with a deep convolutional neuralnetwork. This were applied through software developed to interact between the network and the agentinside the virtual environment. I believe the dataset could have been cut down to about 10 percentof the size and still achieve the research goal. This shows not just the possibility of teaching aneural network a good policy in stochastic environments with supervised machine learning, but alsothat it can draw accurate (enough) conclusions to imitate human behavior when driving a car.
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Renard, Charly. "Nouvelles approches pour la quantification et la réduction de l’adsorption de biomolécules en électrophorèse capillaire : capillaires superhydrophobes et multicouches de polyélectrolytes." Thesis, Montpellier, 2020. http://www.theses.fr/2020MONTS013.
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L’objectif de cette thèse est d’étudier différentes approches pour la modification de la paroi interne des capillaires d’électrophorèse capillaire pour améliorer les efficacités de séparation de biomolécules (peptides et/ou protéines modèles) en milieu acide. Le premier chapitre (hors étude bibliographique) est consacré à l’étude des revêtements superhydrophobes, dans le but d’empêcher l’adsorption des analytes en supprimant toute interaction entre la paroi superhydrophobe et les analytes (absence de mouillage). Un protocole de greffage original a été développé pour obtenir des capillaires superhydrophobes en étudiant l’influence du nombre de couches déposées, la nature du revêtement, et les pressions de remplissage et de rinçage du capillaire lors du dépôt des couches. Des capillaires superhydrophobes ont pu être obtenus, pour la première fois, avec des diamètres internes allant de 50 µm à 180 µm. Les caractéristiques hydrodynamiques et électrocinétiques de ces capillaires ont été étudiées, donnant une longueur de glissement de 23 µm et des efficacités de séparation électrophorétique 2 fois supérieures à celles obtenues sur un capillaire de silice vierge dans les mêmes conditions électrophorétiques. Le second chapitre étudie la génération de microbulles d’air dans des capillaires superhydrophobes. ). Les paramètres expérimentaux (tension, rayonnement UV, marqueur, revêtement superhydrophobe) nécessaires à l’obtention de ces microbulles ont été identifiés). Ces bulles ont été caractérisées (diamètre ~35-39 µm ; longueur ~10 mm ; potentiel zeta ~ -62.6 mV). Le troisième chapitre propose une méthodologie expérimentale, basée sur la théorie de l’électrochromatographie, permettant d’évaluer l’adsorption résiduelle de protéines sur la paroi des capillaires. Cette nouvelle approche présente deux intérêts : (i) pouvoir comparer les performances séparatives sur différents greffages via l’adsorption résiduelle, et (ii) optimiser les paramètres expérimentaux (longueur, diamètre interne, tension appliquée) afin de minimiser l’impact de l’adsorption sur les efficacités de séparation<br>The main objective of this thesis is to study different approaches for the modification of the electrophoresis capillary intern wall to enhance separation efficiency and reproducibility for biomolecules (model peptides and/or proteins) in acidic conditions. The first chapter (outside of bibliographic study) is dedicated to superhydrophobic coatings study. The goal is to prevent analytes adsorption by suppressing any interaction between the superhydrophobic wall and the analytes (anti-wettability). An original coating process has been developed to obtain superhydrophobic capillaries by studying the influence of layers number, coating nature, and filling and flushing pressure during layers deposition. Superhydrophobic coatings have been obtained, for the first time, with diameters from 50 µm to 180 µm. Hydrodynamic and electrokinetic characteristics have been studied, giving slipping length of 23 µm and efficiency separation increased twofold compared to fused silica capillary in the same electrophoretic conditions. The second chapter studies an air microbubbles generation process using superhydrophobic capillaries. The experimental parameters (voltage, UV ray, marker, superhydrophobic coating) needed to obtain those bubbles have been identified. Those bubbles have been characterized (diameter ~35-39 µm; length ~10 mm; zeta potential ~ -62.6 mV). The third chapter offer an experimental methodology, based on the electrochromatography theory, allowing to evaluate the residual adsorption of proteins on the capillary wall. This approach have two interesting points: (i) allowing to compare separative performances of different coatings via residual adsorption, and (ii) optimizing the experimental parameters (length, internal diameter, applied voltage) to minimize the impact of adsorption on the separation efficiencies
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Chen, Yen-Ming. "RC Snubber Design using Root-Loci Approach for Synchronous Buck SMPS." Thesis, University of Waterloo, 2005. http://hdl.handle.net/10012/963.
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This thesis presents an analytical approach using Root-Loci method for designing optimum passive series RC snubbers for continuous-current synchronous buck switch mode power supply (SMPS).
Synchronous buck SMPS is the most popular power converter topology found in modern consumer electronics. It offers relatively good efficiency to target the high-current and low-voltage requirements while it is also relatively inexpensive to implement.
Passive series RC snubbers are simple, efficient and cost-effective open-loop equalizer circuit for synchronous buck SMPS. Its purpose is to control and to balance between the rate of rise and the overshoots of transient switching waveform in order to optimize efficiency and reliability
Existing methods of RC snubber design are solely based on second-order approximation. It is investigated in this research that this approximation is highly inaccurate in SMPS applications because higher order equivalent models are required for the load path of the SMPS. The results using the RC snubbers obtained from existing method are shown to be unsatisfactory without correlation to the calculations and simulations based on second-order approximation. Optimum RC values obtained using Root-Loci approach presented in this thesis are shown to correlate to both Spice simulation and lab measurements.
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Hippold, Judith, and Gudula Rünger. "Task Pool Teams for Implementing Irregular Algorithms on Clusters of SMPs." Universitätsbibliothek Chemnitz, 2006. http://nbn-resolving.de/urn:nbn:de:swb:ch1-200600537.
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The characteristics of irregular algorithms make a parallel implementation difficult, especially for PC clusters or clusters of SMPs. These characteristics may include an unpredictable access behavior to dynamically changing data structures or strong irregular coupling of computations. Problems are an unknown load distribution and expensive irregular communication patterns for data accesses and redistributions. Thus the parallel implementation of irregular algorithms on distributed memory machines and clusters requires a special organizational mechanism for a dynamic load balance while keeping the communication and administration overhead low. We propose task pool teams for implementing irregular algorithms on clusters of PCs or SMPs. A task pool team combines multithreaded programming using task pools on single nodes with explicit message passing between different nodes. The dynamic load balance mechanism of task pools is generalized to a dynamic load balance scheme for all distributed nodes. We have implemented and compared several versions for task pool teams. As application example, we use the hierarchical radiosity algorithm, which is based on dynamically growing quadtree data structures annotated by varying interaction lists expressing the irregular coupling between the quadtrees. Experiments are performed on a PC cluster and a cluster of SMPs.
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Olsson, Emma. "Framtagning av byxor : med smal passform konstruerade efter tyg med stretch." Thesis, Högskolan i Borås, Institutionen Textilhögskolan, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:hb:diva-17346.
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Projekt handlade om att skapa två olika modellgrunder av byxor till företaget Vintage by fé. Företaget arbetar enbart med plaggskisser och måttlistor och har tidigare haft passformsproblem med byxor. De vill därmed ha modellgrunder att utgå ifrån till kommande byxor.Under projektet undersöktes vilka element som är viktiga för att kunna skapa en tajt byxmodell med stretch. Även vilka konstruktionsförändringar som krävs samt hur tygvalet påverkar konstruktionen.Konstruktionen skedde på en befintlig grund som vidareutvecklades till de nya modellgrunderna. Konstruktion, toiler, avprovning och analys av toiler genomfördes kontinuerligt under projektet. Parallellt med arbetet utfördes en omfattande litteraturundersökning, diskussioner hölls med personer med konstruktionserfarenhet samt analyser byxor i butik för att uppnå god passformen.Resultatet av projektet blev två modellgrunder som uppfyllde företagets förväntningar. De slutliga byxorna blev inte uppsydda i toiletyget som använts under utvecklingsprocessen, vilket gjorde att byxorna fick en annorlunda passform. Därmed konstaterades det att tygvalet är en stor faktor av hur ett plaggs passform blir och att tyg och konstruktion måste anpassas efter varandra.Vid konstruktion av tajta byxor krävs det mer än att enbart ta in byxorna i omkretssom litteraturen anvisar.<br>Program: Designteknikerutbildningen
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Cazier, DeAnna June. "The Role of SmpB in the Early Stages of Trans-Translation." BYU ScholarsArchive, 2009. https://scholarsarchive.byu.edu/etd/2126.
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Ribosomes stall on defective messenger RNA transcripts in eubacteria. Without a mechanism to release stalled ribosomes, these cells would die. Transfer-messenger RNA (tmRNA) and small protein B (SmpB) reactivate stalled ribosomes in a process known as trans-translation. Together, tmRNA and SmpB mimic alanyl-tRNA, entering the A site of stalled ribosomes and accepting transfer of the stalled polypeptide. A portion of tmRNA is then positioned as a template for the ribosome to resume translating. The tmRNA open reading frame encodes a proteolysis tag to mark the aberrant polypeptide for degradation and a stop codon to release the ribosome. How are tmRNA and SmpB allowed into stalled ribosomes? In normal translation, decoding mechanisms carefully monitor the anticodon of tRNAs entering the A site and select only those that are complementary to the mRNA codon. How do tmRNA and SmpB get around the decoding machinery? It appears that interactions between the SmpB C-terminal tail and the decoding center are responsible. Using an in vivo tagging assay and an in vitro peptidyl-transfer assay, we monitored the effect of mutations in the SmpB tail on trans-translation. We found that mutations in SmpB that prevent helix formation are unable to support peptidyl transfer. We also found that while mutation of key nucleotides in the ribosomal decoding center severely inhibit peptidyl transfer to normal tRNAs, these mutations do not inhibit peptidyl transfer to tmRNA. We conclude that the SmpB tail stimulates peptidyl transfer by forming a helix that interacts with the ribosome to signal decoding in a novel manner. How is the tmRNA open reading frame positioned for the ribosome to resume translating? Mutation of the tmRNA nucleotide A86 alters reading frame selection. Using a genetic selection, we identified SmpB mutants that restore normal frame selection to A86C tmRNA without altering frame selection on wild-type tmRNA. Through rational mutation of the SmpB tail we identified an SmpB mutant that supports peptidyl transfer but prevents translation of the tmRNA open reading frame. We conclude that SmpB plays a functional role in selecting the tmRNA open reading frame.
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Miller, Mickey R. "The Role of SmpB in Licensing tmRNA Entry into Stalled Ribosomes." BYU ScholarsArchive, 2013. https://scholarsarchive.byu.edu/etd/4162.
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Ribosomes translate the genetic information contained in mRNAs into protein by linking together amino acids with the help of aminoacyl-tRNAs. In bacteria, protein synthesis stalls when the ribosome reaches the 3'-end of truncated mRNA transcripts lacking a stop codon. Trans-translation is a conserved bacterial quality control process that rescues stalled ribosomes. Transfer-messenger RNA (tmRNA) and its protein partner SmpB mimic a tRNA by entering the A site of the ribosome and accepting the growing peptide chain. The ribosome releases the truncated mRNA and resumes translation on the tmRNA template. The open reading frame found on tmRNA encodes a peptide tag that marks the defective nascent peptide for proteolysis. A stop codon at the end of the open reading frame allows the ribosome to be recycled and engage in future rounds of translation.The entry of tmRNA into stalled ribosomes presents a challenge to our understanding of ribosome function because during the canonical decoding process, the ribosome specifically recognizes the codon-anticodon duplex formed between tRNA and mRNA in the A site. Recognition of proper base-pairing leads to conformational changes that accelerate GTP hydrolysis by EF-Tu and rapid accommodation of the tRNA into the ribosome for peptidyl transfer. The puzzle is that tmRNA enters stalled ribosomes and reacts with the nascent peptide in the absence of a codon-anticodon interaction. Instead, SmpB binding in the decoding center begins the rescue process, but it has been unclear how SmpB licenses tmRNA entry into stalled ribosomes. We analyzed a series of SmpB and ribosomal RNA mutants using pre-steady-state kinetic assays for EF-Tu activation and peptidyl transfer. Although the conserved 16S nucleotides A1492 and A1493 play an essential role in canonical decoding, they play little or no role in EF-Tu activation or peptidyl transfer to tmRNA. In contrast, a third nucleotide, G530, stacks with the side chain of SmpB residue His136, inducing conformational changes that lead to GTP hydrolysis by EF-Tu. A portion of the C-terminal tail forms a helix within the mRNA channel, monitoring the length of mRNA bound in the ribosome to avoid aborting productive protein synthesis. Helix formation in the mRNA channel is essential for accommodation and peptidyl transfer, but not for GTP hydrolysis. We show that conserved residues in the tail are essential for EF-Tu activation, accommodation, or translocation to the P site. Our findings lead to a clearer model of how the tmRNA-SmpB complex enters stalled ribosomes.
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Ghilardi, A. "smpx-deficient zebrafish embryos: a tool for studying ciliopathies and deafness." Doctoral thesis, Università degli Studi di Milano, 2014. http://hdl.handle.net/2434/243727.
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Firmly established as a model organism for embryonic developmental studies, zebrafish
is now emerging as an effective system to elucidate the fundamental aspects of several
human diseases. Despite the significant evolutionary distance, gene functions and
pathways are often highly conserved between zebrafish and humans. Previous work has
identified nonsense mutations, associated with hearing deficiency, in the small muscle
protein, X-linked (SMPX) gene and a loss-of-function mechanism underlying this form of
impairment has been proposed. SMPX encodes a cytoskeleton-associated protein that
has been suggested being responsive to mechanical stress. The presence of Smpx in hair
cells of the murine cochlea reinforces the thesis of its importance in ear functioning.
In this study we first provided an overview of the expression of smpx during zebrafish
embryonic development. We showed that from the 4-somite stage, zebrafish smpx was
first expressed in the ciliated organ Kupffer’s vesicle (KV), responsible for the left-right
organs asymmetry, and then, as in mammals, expressed in the heart and in the inner
ear, among other territories. Knock-down of smpx in zebrafish embryos resulted in the
reduced number of cilia in KV and, consequently, the left-right patterning of internal
organs resulted compromised, mimicking human heterotaxy, a disorder of laterality.
Moreover, smpx knock-down resulted in the marked decrease of the number of cilia in
the ear macular regions, providing a possible explanation for the hearing loss in SMPXmutated
patients.
In conclusion, this study contributes to the comprehension of the link between SMPX and
human hearing loss, delivers a novel heterotaxy-candidate gene, and finally provides a
robust animal tool for the future elucidation of the mechanisms behind both
deafness/hearing loss and heterotaxy.
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黃君保 and Kwan-po Wong. "High-speed network interface for commodity SMP clusters." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2000. http://hub.hku.hk/bib/B31225330.
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Wong, Kwan-po. "High-speed network interface for commodity SMP clusters." Hong Kong : University of Hong Kong, 2000. http://sunzi.lib.hku.hk/hkuto/record.jsp?B22505520.
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Ebersson, Joel. "Design och konstruktion av laborationsutrustning till en kraftelektronikkurs." Thesis, Uppsala University, Electricity, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-131542.
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<p>The purpose of this degree project was to build laboratory equipment for a new course in power electronics that starts this autumn 2010 at Uppsala University. The equipment is intended for student labs and it covers the most important areas of the course including rectifying, buck-/boost-converters and PWM-modulation. It is built as one sealed unit where all the electronics are built-in but visible and it has a connection board where students safely can connect the different circuits. The project has advanced from theoretical studies of circuit design, choosing of components and simulations to drawing the printed circuit board (PCB), soldering, case building, final testing and troubleshooting - basically most steps from an early idea to a final product. Measurements on the final product gave about the same results as the earlier simulations of the circuits and the result is overall satisfying.</p><br><p>Syftet med det här examensarbetet var att bygga laborationsutrustning till en ny kurs i kraftelektronik som börjar hösten 2010 på Uppsala Universitet. Utrustningen är avsedd för studentlaborationer och den täcker de viktigaste delarna av kursen inklusive likriktning, buck-/boost-omvandlare och pulsbreddsmodulering (PWM). Laborationsutrustningen är byggd som en sluten enhet där all elektronik är inbyggd men synlig och den har en kopplingsplatta där studenterna säkert kan koppla ihop olika kretsar. Projektet har sträckt sig från teoretiska studier inklusive kretsdesign, komponentval och simuleringar till ritande av kretskortet (PCB-kortet), lödning, byggande av höljet, sluttestning och felsökning - i huvudsak de flesta stegen från en tidig idé till en färdig produkt. Mätningar på den färdiga produkten är ganska lika de tidigare simuleringarna av kretsarna och resultatet är totalt sett tillfredställande.</p>
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Wikingsson, Jon. "Prediktering av radarvågutbredning i troposfären : en smal sak för den taktiske chefen?" Thesis, Swedish National Defence College, Swedish National Defence College, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:fhs:diva-192.
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<p>Detta självständiga arbete i militärteknik behandlar två simuleringsprogram för radarvågutbredning i syfte att undersöka konsekvenserna av dess nyttjande för den taktiske chefen till sjöss. Simuleringsprogrammens användbarhet mäts kvalitativt genom att respektive simuleringsprograms egenskaper ställs mot den taktiske chefens krav. Simulerings-programmen beskrivs utifrån teoretiska egenskaper i respektive program och utvärderas genom simuleringar av en typradar i tre olika vädertypfall. Den taktiske chefens krav grundas på personliga erfarenheter som fartygschef på korvett. Resultatet presenteras i form av positiva och negativa konsekvenser för den taktiske chefen vid nyttjande av respektive program.</p><p> </p><br><p>This is a bachelor thesis in Military Technology which deals with two radar wave propagation simulation programs. The purpose is to examine the consequences of their use for the tactical commander at sea. The simulation programs usability is estimated qualitative by the programs quality and attribute versus the tactical commander demands. The simulation programs are described from their theoretical quality and attribute respectively and evaluated by three simulations of the study’s specific radar in three different weather cases. The tactical commander demands are based on personal experiences as commanding officer of a corvette. The result is presented as positive and negative consequences for the tactical commander when using the simulation programs respectively.</p>
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Lundqvist, Maria. "Smal till varje pris? : En diskursanalys om hur människokroppen framställs i kvällspress." Thesis, Umeå universitet, Institutionen för kultur- och medievetenskaper, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-119045.
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The bachelor dissertation Thin at every cost? is a discourse analysis of how the human body is portrayed in the two Swedish evening tabloid newspapers Aftonbladet and Expressen. The study aims to investigate how the ideal body is portrayed, which qualities that we associate with the ideal body and also where the focal point is. The investigation has been conducted by the implementation of Ernesto Laclau’s and Chantal Mouffe’s discourse analysis as both a theoretical framework and analysis tool, and uses agenda-setting theory, consumerist culture and weight, health and body ideal research to form a scientific base for the analysis. The result of the study shows that the ideal body is thin. To achieve a thin body you must exercise and diet, because being in possession of an overweight body suggests that you are lazy and lack self-control. To promote a thin body most of the researched articles uses health as a concept. To achieve a thin body you must therefore “consume” health. Body image has become a marketing tool and something to buy and sell. If you consume body image and/or health, you will often find yourself being drawn back into the “void”, because the diets and exercises that the articles use to promote weight-loss are often short-term and therefore make you as a reader have to return for another diet, i.e. you have to consume more. The articles often use a big element of control to promote the thin body, but at the same time try to use a positive language to set the tone of the article. Body shaming also occurred, and articles that dealt with the negative aspects of weight loss were also researched and reinforced that the overweight body is often a subject of course language and judgement.
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Carretero, Miguel Adrian. "Aplicação dos conceitos do SMP2 para comunicação entre sistemas legados de simulação." Instituto Nacional de Pesquisas Espaciais, 2012. http://urlib.net/sid.inpe.br/mtc-m19/2011/12.05.20.15.
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Um Simulador de Satélites é composto por modelos que representam o comportamento dos vários subsistemas de um satélite podendo ainda, incluir modelo do ambiente espacial e de estações terrenas de recepção de dados. Muitos destes modelos, em especial os do ambiente espacial, geralmente, não sofrem alterações de um simulador para outro, podendo ser reutilizados ao longo de anos, em diferentes simuladores. Entretanto, esta prática de reutilização não tem sido rotineiramente aplicada. Visando melhorar a interoperabilidade e aumentar o reúso neste tipo de aplicação, a Agência Espacial Européia (ESA) definiu o padrão Simulation Model Portability (SMP), Portabilidade de Modelos de Simulação, que orienta a estruturação de Simuladores de Satélite. O objetivo dessa dissertação é explorar a aplicabilidade dos conceitos do SMP para viabilizar a comunicação entre modelos legados de simulação. Identificados os limites na arquitetura atual do SMP foi proposta uma extensão aos mecanismos de comunicação desta arquitetura de modo a permitir a inclusão dos modelos legados a um simulador que seja conforme o SMP. Uma demonstração da solução dada ao mecanismo de comunicação proposto é feita através de um estudo de caso. Essa dissertação mostra uma solução para aplicação dos mecanismos para interoperabilidade entre modelos legados de simulação se beneficiando da padronização para reforçar o reúso de modelos e de mecanismos que dão suporte a um simulador. Entretanto, a solução ainda mantém a dependência da plataforma computacional e de uma linguagem orientada a objetos.<br>A Satellite Simulator is composed of a set of models that represents the behavior of the various satellite subsystems. It may also include a model of the space environment and of the ground stations. Many of these models, especially the space environment model do not change from one simulator to another and can be reused over the years. However, this is not a common practice. In order to improve interoperability and increase re-use of the models, the European Space Agency (ESA) created a standard named Simulation Model Portability (SMP) that guides the development of Satellite Simulators. The objective of this work is to explore the applicability of the concepts of SMP to enable communication between legacy simulation models. After identifying limitations in the current SMP architecture it was proposed an extension of the SMP communication mechanisms to allow the addition of legacy models to a SMP simulator. A case study was used to demonstrate the results of the proposed communication mechanism. This work also presents a computational implementation of the interoperability mechanisms between the legacy simulation models (which takes advantage from standardization) to enhance the reuse of models and mechanisms that support a simulator system. However, this solution still preserves its dependence on the computing platform and an on an object-oriented language.
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Akram, Farhan. "Gate driver solutions for high power density SMPS using Silicon Carbide MOSFETs." Thesis, Mittuniversitetet, Institutionen för elektronikkonstruktion, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:miun:diva-41188.
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Discrete silicon carbide (SiC) power devices have unique characteristics that outpace those of silicon (Si) counterparts. The improved physical features have provided better faster switching, greater current densities, lower on-resistance, and temperature performances. However, there is lack of suitable commercial gate drivers that are compatible for high-voltage, and high-speed devices. There has been a great research effort required for the advancement of gate drivers for high voltage SiC transistors. A drive circuit for a SiC MOSFET needs to be optimized in normal operation to give best efficiency and same drive circuit should secure the MOSFET under unsuitable conditions. To ensure the rapid switching of these advanced SiC MOSFETs, a gate driver capable of providing the high current capability is required. In this work, three different high-power-density, high-speed, and high-noise-immunity gate driver modules for 10 kV SiC MOSFET were built and optimized. Double-pulse test was developed for the dynamic characterization of SiC MOSFETs and gate drivers. This setup provided clean measurements of DUT voltage and current under well-defined conditions and correlated to simulation results. Designed gate drivers have thoroughly investigated to test and compare it with our future design. The influential parameters such as dV/dt, dI/dt, and gate driving capability of gate driver were adjusted according to the requirements. The short circuit protection test was performed to check the reliability of driver modules in worst conditions. Furthermore, a DC-DC converter was designed and tested with the advanced gate drivers. The driver modules were tested in designed converter under different load conditions and influential parameters were successfully demonstrated. The driver modules effectively helped in reducing the EMI and switching losses. These designed gate drivers and prototype converter provide all the attractive features and can be widely implemented in industrial applications for energy efficient systems.
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Sundqvist, Malin, and Carlsson Sofia Zäll. "En smal och krokig stig : en studie om behovsformulering i elevers åtgärdsprogram." Thesis, Högskolan Kristianstad, Sektionen för lärande och miljö, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:hkr:diva-17020.
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Detta examensarbete behandlar vad som skrivs under rubriken behov i åtgärdsprogram och huruvida skolor följer Skolverkets riktlinjer från 2014, gällande hur behov i åtgärdsprogram bör formuleras. Studien baseras på 65 åtgärdsprogram från åk 4-6 som vi har begärt, och fått in, från 19 slumpmässigt utvalda skolor i hela Sverige. Åtgärdsprogrammen tolkades utifrån ett relationellt och kategoriskt perspektiv med en hermeneutisk ansats. Vid vår analys framkom det sju olika teman under rubrikerna svårigheter och behov. Dessa teman visar att skolor i stor utsträckning skriver elevens behov på ett sätt som inte överensstämmer med Skolverkets senaste riktlinjer, och att behov i många fall inte utgörs av just behov, utan skrivs som svårigheter, diagnoser, personliga egenskaper, oönskat beteende och oreflekterat tyckande kring eleven. Resultatet visar att en majoritet av de åtgärdsprogram vi har analyserat representerar ett kategoriskt perspektiv. Tidigare forskning visar på hur formuleringar som dessa kategoriserar elever och har en identitetsskapande funktion hos eleven. Om skolproblem knyts till individen, leder detta inte till förändringar i lärmiljön. Forskning visar också att dessa formuleringar kring elever kan upprätthålla och underbygga ett kategoriskt perspektiv i skolan. En tänkbar anledning till att Skolverkets riktlinjer har svårt att få genomslag i praktiken är att dessa i sig lämnar stort tolkningsutrymme för skolledare och skolpersonal. Examensarbetet kan visa på att Skolverkets riktlinjer från före 2014, där det rekommenderades att elevers svårigheter skulle beskrivas under rubriken behov, fortfarande följs.
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Watts, Talina Christensen. "Genetic analysis of the role of SmpB in determining frame on tmRNA /." Diss., CLICK HERE for online access, 2008. http://contentdm.lib.byu.edu/ETD/image/etd2501.pdf.
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Souza, Nicole Menezes de. "Avaliação da imunogenicidade da SMTL-13, uma lectina secretada de Mycobacterium tuberculosis." Florianópolis, 2012. http://repositorio.ufsc.br/xmlui/handle/123456789/99321.
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Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Biotecnologia e Biociências<br>Made available in DSpace on 2013-03-04T19:12:16Z (GMT). No. of bitstreams: 1
305008.pdf: 1294464 bytes, checksum: 1c308bc869ef17da3ff0b5b2d4ed979c (MD5)<br>A tuberculose, causada principalmente pelo bacilo Mycobacterium tuberculosis (Mtb), é uma doença responsável por aproximadamente 1,4 milhão de mortes anuais no mundo. Dado seu grande impacto na saúde pública, aliado à ausência de um modelo vacinal eficaz e ao surgimento de cepas resistentes, existe uma clara necessidade na busca por novos imunógenos, bem como novas estratégias de prevenção, diagnóstico e tratamento da TB. Nosso grupo caracterizou um possível antígeno vacinal, a lectina de 13 kDa secretada pelo Mtb (sMTL-13), que apresentou alto potencial antigênico na indução de respostas imunes celulares (IFN-?/PBMC) e humorais (IgG/soro) em pacientes com tuberculose ativa. A natureza ubíqua das lectinas reflete o seu envolvimento em diversos mecanismos celulares, tornando significante o estudo da sua interação em processos biológicos. Visando obter informações acerca da imunogenicidade da sMTL-13, este trabalho demonstrou que, além de secretada, esta proteína possui capacidade de ficar ancorada na parece celular do Mtb, provavelmente pela sua sequência conhecida como peptídeo sinal, tendo uma possível função na interação inicial do bacilo com células apresentadoras de antígeno (APCs), pois a incubação do Mtb com a D-Galactose, carboidrato que possui afinidade pela sMTL-13, e não L-Galactose, foi capaz de impedir essa interação. Esta lectina também foi capaz de induzir produção de citocinas pró-inflamatórias por APCs e essas foram capazes de levar a uma proliferação celular de linfócitos T CD4+ antígenos-específicos, indicando que a sMTL-13 possui atividade imunogênica. Estes dados demonstram que há uma importante regulação na interação de proteínas ligantes de carboidratos com o APCs e que a sMTL-13 pode atuar como padrão molecular associado a patógenos (PAMP) do Mtb, porém há a necessidade de mais estudos envolvendo a interação dessa lectina com células do sistema imune.
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Andersson, Nina, and Emelie Haglund. ""Jag vill inte vara den där tjocka mamman" : En studie kring kvinnligt kroppsideal under och efter en graviditet." Thesis, Halmstad University, School of Social and Health Sciences (HOS), 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-3106.
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<p>Studien grundar sig på kvalitativa intervjuer med åtta kvinnliga informanter. Syfte med studien är att undersöka hur en grupp nyblivna mödrar eller gravida, själva beskriver egna och andras krav på att återgå till den ursprungliga kroppsformen eller det "ideal" som basuneras ut genom olika budskap via media, efter sina graviditeter.diskursen om kvinnokroppens ideal ...</p><p> </p>
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Rauch, Travis M. "Savage Modeling and Analysis Language (SMAL) metadata for tactical simulations and X3D visualizations." Thesis, Monterey, Calif. : Springfield, Va. : Naval Postgraduate School ; Available from National Technical Information Service, 2006. http://library.nps.navy.mil/uhtbin/hyperion/06Mar%5FRauch.pdf.
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Thesis (M.S. in Modeling, Virtual Environments, and Simulation (MOVES))--Naval Postgraduate School, March 2006.<br>Thesis Advisor(s): Don Brutzman. "March 2006." Includes bibliographical references (p. 219-222). Also available online.
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Öberg, Anette, and Linda Ståhl. "Tjock i en smal värld : Sjuksköterskans pedagogiska funktion vid viktnedgång hos överviktiga patienter." Thesis, Mittuniversitetet, Institutionen för hälsovetenskap, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:miun:diva-13863.
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Bakgrund: Av den globala befolkningen, 2005, var 1,6 miljarder vuxna överviktiga och minst 400 miljoner vuxna led av fetma. Sjuksköterskor ska ha förmågan att uppfatta och förebygga hälsorisker och motivera till förändrad livsstil som till exempel viktminskning. Syfte: Att få förståelse för patienter med övervikt samt att belysa sjuksköterskans pedagogiska funktion vid viktnedgång hos dessa patienter. Metod: Litteraturstudie med 18 klassificerade och värderade vetenskapliga artiklar som analyserats och bearbetats. Resultat: Analysen gav två kategorier och fem subkategorier; den överviktige patientens upplevelser – beslut, försvarsmekanismer och hinder, motivation samt sjuksköterskans pedagogiska funktion – kommunikation och relation, stöd. Diskussion: Sjuksköterskan spelar en viktig roll i hanteringen av överviktiga och feta patienter och bemötandet de får är en avgörande faktor för viktnedgången. Slutsats: Då övervikt och fetma utvecklats till en global epidemi finns i dag ett stort behov av att hälso- och sjukvården arbetar förebyggande mot övervikt och fetma.
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Guo, Shuibao. "High performance digital controller for high-frequency low-power integrated DC/DC SMPS." Lyon, INSA, 2009. http://theses.insa-lyon.fr/publication/2009ISAL0033/these.pdf.
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Bien qu'un sujet de recherché important, le contrôle numérique n'a pas encore été appliqué en pratique aux convertisseurs de tension à découpage basse-puissance. Les appareils portables sont encore conçus avec des convertisseurs de tension à boucle de contrôle analogique. Ceci est dû à la complexité de l'implémentation d'un contrôleur numérique, aux contraintes de coût et l'absente d'architecture de contrôleur ayant prouvé leur efficacité pour de hautes fréquences de découpage. Les compromis entre performances, consommation, coût silicium limitent encore le développement des contrôleurs numériques. Les outils de développement efficaces existent pour concevoir des structures de contrôle numérique dans le contexte de la haute intégration (VLSI), dont des ASICs et des FPGAs. Il est plus commode d'aborder la conception de boucles de contrôles numériques dans l'environnement des régulateurs de tension à découpage pour les circuits intégrés sur batterie. Les travaux dans ce contexte sont généralisables à celui des FPGAs et à plus large échelle à des dispositifs de conversion d'énergie continue de plus forte puissance. L'objet des travaux de thèse concerne l'exploitation de diverses architectures des blocs constituants un contrôleur numérique : les lois de commande et la traduction en largeur d'impulsion des décisions en temps-réel du contrôleur (Digital pulse-width modulation). Par ailleurs, faute d'un accès matériel suffisant à une vérification expérimentale sous la forme d'ASICs, les résultats concernent en premier lieu la méthodologie de développement et la vérification couvre un grand nombre de besoins industriels et prépare la perspective de travaux dans un contexte d'intégration ultime basse puissance<br>Despite being a popular research topic, digital control is still seldom applied in practical low-power high-frequency integrated SMPS converters. Phones, PDAs and music/video players are still mainly designed with analog PWM control inside the voltage regulator blocks. This is mainly due to the apparent complexity of implementation, cost constraint and absence of digital controller architectures that can support operation at switching frequencies significantly higher than 1MHz with low-power consumption features. Broader acceptance of digital techniques in low-power high-frequency SMPS is still hampered by practical problems of the combination of cost issues, trade-off performances and power consumption. However, with the rapid development of Very Large-Scale Integration (VLSI) technologies and CMOS manufacturing technique, and associated with their design tools in the last decade, it is now very possible to realize the high performance digital control in power electronics system by high-speed low-power digital devices (FPGA, ASIC, etc). With these advantages, the implementation of digital controller has become more feasible for low-power high-frequency SMPS design in portable electronics applications. The research interest of the thesis is to explore practical ways of incorporating advantages of digital control in practical implementation, investigates issues of digital controller implementation at lower power levels, gives detailed guidelines for digital controller design and hardware selection, and proposes new hardware solutions for the main functional digital controller blocks. Two main objectives of this work focus the implementation of high-resolution high-frequency digital PWM (DPWM) and high-performance digital control algorithms for SMPS in FPGA-based realization
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Kotte, Hari Babu. "High Speed (MHz) Switch Mode Power Supplies (SMPS) using Coreless PCB Transformer Technology." Licentiate thesis, Mittuniversitetet, Institutionen för informationsteknologi och medier, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:miun:diva-13964.
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The most essential unit required for all the electronic devices is the Power Supply Unit (PSU). The main objective of power supply designers is to reduce the size, cost and weight, and to increase the power density of the converter. There is also a requirement to have a lower loss in the circuit and hence in the improvement of energy efficiency of the converter circuit. Operating the converter circuits at higher switching frequencies reduces the size of the passive components such as transformers, inductors, and capacitors, which results in a compact size, weight, and increased power density of the converter. At present the switching frequency of the converter circuit is limited due to the increased switching losses in the existing semiconductor devices and in the magnetic area, because of increased hysteresis and eddy current loss in the core based transformer. Based on continuous efforts to improve the new semi conductor materials such as GaN/SiC and with recently developed high frequency multi-layered coreless PCB step down power transformers, it is now feasible to design ultra-low profile, high power density isolated DC/DC and AC/DC power converters. This thesis is focussed on the design, analysis and evaluation of the converters operating in the MHz frequency region with the latest semi conductor devices and multi-layered coreless PCB step-down power and signal transformers. An isolated flyback DC-DC converter operated in the MHz frequency with multi-layered coreless PCB step down 2:1 power transformer has been designed and evaluated. Soft switching techniques have been incorporated in order to reduce the switching loss of the circuit. The flyback converter has been successfully tested up to a power level of 10W, in the switching frequency range of 2.7-4 MHz. The energy efficiency of the quasi resonant flyback converter was found to be in the range of 72-84% under zero voltage switching conditions (ZVS). The output voltage of the converter was regulated by implementing the constant off-time frequency modulation technique. Because of the theoretical limitations of the Si material MOSFETs, new materials such as GaN and SiC are being introduced into the market and these are showing promising results in the converter circuits as described in this thesis. Comparative parameters of the semi conductor materials such as the vi energy band gap, field strengths and figure of merit have been discussed. In this case, the comparison of an existing Si MOSFET with that of a GaN MOSFET has been evaluated using a multi-layered coreless PCB step-down power transformer for the given input/output specifications of the flyback converter circuit. It has been determined that the energy efficiency of the 45 to 15V regulated converter using GaN was improved by 8-10% compared to the converter using the Si MOSFET due to the gate drive power consumption, lower conduction losses and improved rise/fall times of the switch. For some of the AC/DC and DC/DC applications such as laptop adapters, set-top-box, and telecom applications, high voltage power MOSFETs used in converter circuits possess higher gate charges as compared to that of the low voltage rating MOSFETs. In addition, by operating them at higher switching frequencies, the gate drive power consumption, which is a function of frequency, increases. The switching speeds are also reduced due to the increased capacitance. In order to minimize this gate drive power consumption and to increase the frequency of the converter, a cascode flyback converter was built up using a multi-layered coreless PCB transformer and this was then evaluated. Both simulation and experimental results have shown that with the assistance of the cascode flyback converter the switching speeds of the converter were increased including the significant improvement in the energy efficiency compared to that of the single switch flyback converter. In order to further maximize the utilization of the transformer, to reduce the voltage stress on MOSFETs and to obtain the maximum power density from the power converter, double ended topologies were chosen. For this purpose, a gate drive circuitry utilising the multi-layered coreless PCB gate drive transformer was designed and evaluated in both a Half-bridge and a Series resonant converter. It was found that the gate drive power consumption using this transformer was less than 0.8W for the frequency range of 1.5-3.5MHz. In addition, by using this gate drive circuitry, the maximum energy efficiency of the series resonant converter was found to be 86.5% with an output power of 36.5W.
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Morken, Anders, and Per Ottar Ribe Pahr. "Apache Derby SMP scalability : Investigating limitations and opportunities for improvement." Thesis, Norwegian University of Science and Technology, Department of Computer and Information Science, 2007. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-8734.
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<p>This report investigates the B-Tree access method of Apache Derby. Apache Derby is an open source Java database system. The detailed focus of the report is on performance aspects of the Derby page latch implementation. Our focal point is the interaction between the B-Tree access method and page latching, and the impact of these components on the ability of Derby to scale on multiprocessor systems. Derby uses simple and in the single-threaded case inexpensive exclusive-only page latches. We investigate the impact on scalability of this design, and contrast it with a version of Derby modified to support both shared read-only and exclusive page access for lookups in index structures. This evaluation is made for single-threaded as well as multi-threaded scenarios on multiprocessing systems. Based on analyses of benchmark results and profiler traces, we then suggest how Derby may be able to utilize modern Java locking primitives to improve multiprocessor scalability.</p>
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Kubáčová, Jana. "Souhrnné modely hodnocení a jejich aplikace v SMP, a. s." Master's thesis, Vysoká škola ekonomická v Praze, 2007. http://www.nusl.cz/ntk/nusl-1449.
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Práce se zaměřuje na souhrnné modely hodnocení, které umožňují z globálního hlediska posoudit finanční situaci podniku.Jádro tvoří bonitní a bankrotní modely jako Altmanův model, indexy IN, Tafflerův model, Kralickův Quicktest, Tamariho model, Index bonity, Grünwaldův index bonity, Bilanční analýza podle R. Douchy a Beermanova diskriminační funkce, práce dále obsahuje i Pollakovu metodu hodnocení vitality podniku. Smyslem bylo zhodnotit vývoj finančního zdraví podniku Severomoravská plynárenská, a. s. a provést komparaci výsledků aplikovaných modelů.
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Liu, Boya. "Comparison of Foaming Properties between Chelated Reconstituted SMP and Caseinates." DigitalCommons@CalPoly, 2016. https://digitalcommons.calpoly.edu/theses/1648.
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Caseinate powders have been well accepted because of their foaming properties. In this study, 10% solution of reconstituted skim milk powder (SMP) chelated with sodium hexametaphosphate (SHMP) and trisodium citrate (TSC) at 1 mEq, 50 mEq, and 100 mEq were prepared to conduct a comparison with sodium caseinate, potassium caseinate, and calcium caseinate solutions. Foamability, foam stability as well as the preferential locations of αs-casein, β-casein and !-casein in their foams were analyzed. It was hypothesized that the foamability, foam stability and the preferential locations of these three caseins in the milk foams are different from treatment to treatment. Milk foam was generated with an air- injection method at a flow rate of 0.30 L/M for 18 seconds. Foam stability was measured through half-life method. The foam composition was quantified with sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) method. Analysis of Variance (ANOVA) test results concluded that there were no significant differences detected in foamability (p>0.05). On the other hand, foam stability differed significantly among the treatments. Foams of reconstituted SMP-treated with 1 mEq SHMP and TSC were significantly more stable compared to other treatments (p < 0.05), β-casein (p>0.05) and !-casein (p>0.05). In conclusion, the addition of calcium chelating salts might increase the foamability to the same level as caseinate solutions. Furthermore, the study proved that the combination of calcium chelating salts and chelator levels is able to alter the foam stability.
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Tavassoli, Mohammad hosein. "Exploring the Critical Success Factors of Industrial Clustering; SMIL as an illustrative case study." Thesis, Linköping University, Department of Management and Engineering, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-53706.
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<p>“Industrial cluster” is one type of agglomeration and the concept has been increasingly used and recognized as an essential part of regional development strategies and thinking in recent years. However, there has <em>not</em> been an explicit collection-work devoted to exploring the <strong>Critical Success Factors</strong> (CSFs). So, this thesis aims to explore such CSFs based on literature review as well as illustrative case study.</p><p>The major finding of this thesis is exploration of 18 (possible) CSFs based on extensive literature review and grouping them into 5 success categories (see Table 3 for the full list of them). The contribution of each explored CSFs to the success of a typical cluster has been checked, in order to assure that each explored CSF is really functioning as a CSF. Then, SMIL as a real-life cluster with 25 years old in Linköping region of Sweden is used as an illustrative case study, in order to observe the literature-based explored CSFs in reality.</p><p>In addition, based on both literature review and illustrative case, a number of relations between CSFs have been identified. In particular, such relations can be described as; some CSFs may lead to creation of some other CSFs.</p><p>Illustrative case study shows that some of the literature-based explored CSFs are not observable in a real-life cluster, i.e. SMIL. The main reasons for such lack of the validity of some CSFs in SMIL cluster are mostly deal with the SMIL (association) as the node organizer of SMIL cluster. Such main reasons are; weak linkage between SMIL association and some of its actors, and/or being out of the scope of SMIL’s agenda and focus.</p><p>The other finding of this thesis is that; in terms of resource, network-based clusters with network activities (such as SMIL cluster) are richer in soft resources (such as pre and post existence of knowledge in the region) than hard ones (like infrastructural resources).</p><p>At the end, there are some recommendations for SMIL in order to improve its overall performance, by considering some possible CSFs.</p>
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Andersson, Karin, and Hanna Mac. ""Rynkfri, smal och snygg" : En kvalitativ studie om kvinnors upplevelser av kvinnoidealet i mediereklam." Thesis, Stockholms universitet, Sociologiska institutionen, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-77393.
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Syftet med studien var att undersöka hur en grupp kvinnor i åldern mellan 20-30 år upplever och förhåller sig till det kvinnoideal som framställs i mediereklam. Studien byggde på en kvalitativ ansats i ett försök att söka reda på deras gemensamma uppfattningar om fenomenet och hur de upplevde att de påverkas av den kvinnliga framställningen. Av den anledningen utfördes semistrukturerade intervjuer som datainsamlingsmetod eftersom den ger de intervjuade personerna en möjlighet att utveckla sina svar. Då kvinnor tillhör en av de största konsumtionsgrupperna ansåg vi att det var relevant att studera hur denna grupp kunde påverkas av mediereklamens framställningar. Intervjufrågorna ställdes utifrån ett urval av reklambilder från de idag största företagen i Sverige inom mode och skönhet. Tidigare forskning lyfter fram medias roll i producering och reproducering av kvinnlighet och manlighet, samt dess inflytande på individers självbild och verklighetsuppfattningar. Eftersom det huvudsakliga syftet med reklam är att sälja en produkt är denna framställning inte alltid en korrekt avspegling av den objektiva verkligheten. För att få en bättre förståelse för hur reklamen kan tolkas utgick vi i den teoretiska bakgrunden från Butlers performativitetsbegrepp, Connells utgångspunkter om en genusordning samt Goffmans teorier om hyperritualisering.Resultatet visade att informanterna upplevde att de påverkades av mediereklamens framställningar. Informanterna var väl medvetna om att medias framställning av kvinnoidealet inte är en riktig avspegling av verkligheten, samtidigt fanns det ändå en strävan att komma så nära idealbilden som möjligt. Detta bekräftar Butlers, Connells och Goffmans teorier om att kvinnlighet och manlighet är någonting som är socialt konstruerat och fastläggs av den rådande normen i samhället.
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Gibson, Courtney R. "Impact of communication layer performance on shared virtual memory protocols for clusters of SMPs." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0020/MQ53432.pdf.
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Johansson, Margita. "När midjan var smal och kepsen satt på svaj : Efterkrigstidens mentalitet genom journalfilmens lins." Thesis, Uppsala universitet, Historiska institutionen, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-322575.
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This paper studies how gender roles and the Swedish nation are portrayed in newsreels during 1945 – 1959. Almost a hundred films have been analyzed to examine norms regarding looks, professions and roles in society. Women are mostly portrayed as housewives and their appearance is thoroughly described, whereas for men their actions are in focus and more important than their looks. But at the same time women gain access to the labor market during this period and gender roles start transforming. There is progression towards a more equal portrayal of men and women. For example, the newsreels show female police officers and taxi drivers, and men participating in infant care and housework. A deeply rooted culture during is to period is to be rational, optimistic and modern. Technical progress and standardization permeates housework and society as a whole. Engineering and new science is highlighted and there are no obstacles for development. There is a tendency for romantic nationalism, with idyllic pictures of Swedish landscape and natural resources. Newsreels is a mass medium that is not a passive reflection of the current mentality but it also produces new ideas and can influence the audience by showing a more modern way of life and loosened gender roles.