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Journal articles on the topic 'SNAO'

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Published: 4 June 2021

Last updated: 8 February 2022

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1

Folland, Chris K., Jeff Knight, Hans W. Linderholm, David Fereday, Sarah Ineson, and James W. Hurrell. "The Summer North Atlantic Oscillation: Past, Present, and Future." Journal of Climate 22, no. 5 (2009): 1082–103. http://dx.doi.org/10.1175/2008jcli2459.1.

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Abstract Summer climate in the North Atlantic–European sector possesses a principal pattern of year-to-year variability that is the parallel to the well-known North Atlantic Oscillation in winter. This summer North Atlantic Oscillation (SNAO) is defined here as the first empirical orthogonal function (EOF) of observed summertime extratropical North Atlantic pressure at mean sea level. It is shown to be characterized by a more northerly location and smaller spatial scale than its winter counterpart. The SNAO is also detected by cluster analysis and has a near-equivalent barotropic structure on

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2

Ahlbäck Öberg, Shirin, and Louise Bringselius. "Professionalism and organizational performance in the wake of new managerialism." European Political Science Review 7, no. 4 (2014): 499–523. http://dx.doi.org/10.1017/s1755773914000307.

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With New Public Management came the idea that public organizations should be led by professional managers, rather than by professionals. This has been referred to as new managerialism. This article explores how new managerialism may affect professional autonomy in a public organization that enjoys a high – and constitutionally protected – degree of organizational autonomy. A framework distinguishing between organizational and occupational professionalism is adopted, in a 10-year case study of the Swedish National Audit Office (SNAO). The study shows how the autonomy of professionals at the SNA

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3

Hong, Xiaowei, Riyu Lu, and Shuanglin Li. "Differences in the Silk Road Pattern and Its Relationship to the North Atlantic Oscillation between Early and Late Summers." Journal of Climate 31, no. 22 (2018): 9283–92. http://dx.doi.org/10.1175/jcli-d-18-0283.1.

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Abstract The Silk Road Pattern (SRP) is an upper-tropospheric teleconnection pattern along the Asian westerly jet in summer on the interannual time scale, and it exerts great influences on the climate of the Eurasian continent. Results in the present study indicate that the SRP exhibits considerable distinctions between early and late summers (i.e., 1 June–9 July and 10 July–31 August, respectively). The SRP is stronger and more geographically fixed in late summer in comparison with its counterpart in early summer. Furthermore, the SRP is closely connected with the summer North Atlantic Oscill

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4

Wang, Ziqian, Song Yang, Ngar-Cheung Lau, and Anmin Duan. "Teleconnection between Summer NAO and East China Rainfall Variations: A Bridge Effect of the Tibetan Plateau." Journal of Climate 31, no. 16 (2018): 6433–44. http://dx.doi.org/10.1175/jcli-d-17-0413.1.

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Although the impact of the North Atlantic Oscillation (NAO), especially the antecedent NAO in winter and spring, on East Asian summer climate has been studied extensively, the possible connection from the summer NAO (SNAO) and then the Tibetan Plateau (TP) to East China summer rainfall remains unclear. This study reveals that on interannual time scales the SNAO is significantly correlated with the variations of East China summer rainfall and the thermal forcing of the TP provides an intermediate bridge effect in this Eurasian teleconnection. The SNAO primarily regulates the rainfall variabilit

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Osborne, Joe M., Mat Collins, James A. Screen, Stephen I. Thomson, and Nick Dunstone. "The North Atlantic as a Driver of Summer Atmospheric Circulation." Journal of Climate 33, no. 17 (2020): 7335–51. http://dx.doi.org/10.1175/jcli-d-19-0423.1.

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AbstractSkill in seasonal forecasts in the Northern Hemisphere extratropics is mostly limited to winter. Drivers of summer circulation anomalies over the North Atlantic–European (NAE) sector are poorly understood. Here, we investigate the role of North Atlantic sea surface temperatures (SSTs) in driving summer atmospheric circulation changes. The summer North Atlantic Oscillation (SNAO), the leading mode of observed summer atmospheric circulation variability in the NAE sector, is correlated with a distinct SST tripole pattern in the North Atlantic. An atmospheric general circulation model is u

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Zveryaev, Igor I., and Abdel A. Hannachi. "Summertime variability of Mediterranean evaporation: competing impacts from the mid latitudes teleconnections and the South Asian monsoon." Theoretical and Applied Climatology 144, no. 1-2 (2021): 779–91. http://dx.doi.org/10.1007/s00704-021-03577-1.

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AbstractInterannual variability of Mediterranean evaporation and its links to regional climate during summer are investigated based on evaporation data from the Woods Hole Oceanographic Institution dataset. An EOF (Empirical Orthogonal Function) analysis performed on the monthly means (i.e., separately for June, July, August, and September time series) revealed two leading modes of evaporation variability, characterized by the monopole (EOF-1) and zonal dipole (EOF-2) patterns. These modes explain altogether more than 60% of the total variability of Mediterranean evaporation for each month. In

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7

Schulte, L., J. C. Peña, F. Carvalho, et al. "A 2600-year history of floods in the Bernese Alps, Switzerland: frequencies, mechanisms and climate forcing." Hydrology and Earth System Sciences 19, no. 7 (2015): 3047–72. http://dx.doi.org/10.5194/hess-19-3047-2015.

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Abstract. A 2600-year long composite palaeoflood record is reconstructed from high-resolution delta plain sediments of the Hasli–Aare floodplain on the northern slope of the Swiss Alps. Natural proxies compiled from sedimentary, geochemical and geomorphological data were calibrated by textual and factual sources and instrumental data. No fewer than 12 of the 14 historically recorded extreme events between 1480 and the termination of the Hasli–Aare river channel correction in 1875 were also identified by coarse-grained flood layers, log(Zr / Ti) peaks and factor 1 anomalies. Geomorphological, h

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8

Schulte, L., J. C. Peña, F. Carvalho, et al. "A 2600 year history of floods in the Bernese Alps, Switzerland: frequencies, mechanisms and climate forcing." Hydrology and Earth System Sciences Discussions 12, no. 3 (2015): 3391–448. http://dx.doi.org/10.5194/hessd-12-3391-2015.

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Abstract. A 2600 yr long composite palaeoflood record is reconstructed from high-resolution delta plain sediments of the Hasli–Aare floodplain on the northern slope of the Swiss Alps. Natural proxies compiled from sedimentary, geochemical and geomorphological data were calibrated by textual and factual sources and instrumental data. No fewer than 12 of the 14 historically recorded extreme events between 1480 and the termination of the Hasli–Aare Correction in 1875 were also identified by coarse-grained flood layers, log(Zr/Ti) peaks and Factor 1 anomalies. Geomorphological, historical and inst

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9

Trouet, Valerie. "A Tree-Ring Based Late Summer Temperature Reconstruction (AD 1675–1980) for the Northeastern Mediterranean." Radiocarbon 56, no. 4 (2014): S69—S78. http://dx.doi.org/10.2458/azu_rc.56.18323.

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This article presents a late summer temperature reconstruction (AD 1675–1980) for the northeastern Mediterranean (NEMED) that is based on a compilation of maximum latewood density tree-ring data from 21 high-elevation sites. This study applied a novel approach by combining individual series from all sites into one NEMED master chronology. This approach retains only the series with a strong and temporally robust common signal and it improves reconstruction length. It further improved the regional character of the reconstruction by using as a target averaged gridded instrumental temperature data

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10

Trouet, Valerie. "A Tree-Ring Based Late Summer Temperature Reconstruction (AD 1675–1980) for the Northeastern Mediterranean." Radiocarbon 56, no. 04 (2014): S69—S78. http://dx.doi.org/10.1017/s0033822200050372.

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This article presents a late summer temperature reconstruction (AD 1675–1980) for the northeastern Mediterranean (NEMED) that is based on a compilation of maximum latewood density tree-ring data from 21 high-elevation sites. This study applied a novel approach by combining individual series from all sites into one NEMED master chronology. This approach retains only the series with a strong and temporally robust common signal and it improves reconstruction length. It further improved the regional character of the reconstruction by using as a target averaged gridded instrumental temperature data

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11

Linderholm, Hans W., and Chris K. Folland. "Summer North Atlantic Oscillation (SNAO) variability on decadal to palaeoclimate time scales." Past Global Changes Magazine 25, no. 1 (2017): 57–60. http://dx.doi.org/10.22498/pages.25.1.57.

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12

Linderholm, Hans W., Chris K. Folland, and Alexander Walther. "A multicentury perspective on the summer North Atlantic Oscillation (SNAO) and drought in the eastern Atlantic Region." Journal of Quaternary Science 24, no. 5 (2009): 415–25. http://dx.doi.org/10.1002/jqs.1261.

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13

Linderholm, Hans W., C. Folland, J. Knight, D. Fereday, S. Ineson, and J. W. Hurrell. "Influences of the Summer North Atlantic Oscillation (SNAO) on regional climate – from the past to the future." IOP Conference Series: Earth and Environmental Science 6, no. 7 (2009): 072039. http://dx.doi.org/10.1088/1755-1307/6/7/072039.

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14

Cabaniols, J. P., V. Ravichandran, and P. A. Roche. "Phosphorylation of SNAP-23 by the Novel Kinase SNAK Regulates t-SNARE Complex Assembly." Molecular Biology of the Cell 10, no. 12 (1999): 4033–41. http://dx.doi.org/10.1091/mbc.10.12.4033.

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The docking and fusion of cargo-containing vesicles with target membranes of eukaryotic cells is mediated by the interaction of SNARE proteins present on both vesicle and target membranes. In many cases, the target membrane SNARE, or t-SNARE, exists as a complex of syntaxin with a member of the SNAP-25 family of palmitoylated proteins. We have identified a novel human kinase SNAK (SNARE kinase) that specifically phosphorylates the nonneuronal t-SNARE SNAP-23 in vivo. Interestingly, only SNAP-23 that is not assembled into t-SNARE complexes is phosphorylated by SNAK, and phosphorylated SNAP-23 r

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15

Zhu, Liangjun, Qichao Yao, David J. Cooper, Shijie Han, and Xiaochun Wang. "Response of <i>Pinus sylvestris</i> var. <i>mongolica</i> to water change and drought history reconstruction in the past 260 years, northeast China." Climate of the Past 14, no. 8 (2018): 1213–28. http://dx.doi.org/10.5194/cp-14-1213-2018.

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Abstract. We present a 260-year annual Palmer drought severity index (PDSI) reconstruction based on a tree-ring width chronology of Scots pine (Pinus sylvestris var. mongolica) from four sample sites in the central Daxing'an Mountains, northeast China. The reconstruction equation explained 38.2 % of the variance of annual PDSI in the calibration period from 1911 to 2010. Our reconstruction confirmed the local historical documents and other nearby hydroclimate reconstructions. Drought in the 1920s–1930s was more severe in the Daxing'an Mountains than in the surrounding areas. A slight moisture

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16

Linderholm, Hans W., Andrea Seim, Tinghai Ou, et al. "Exploring teleconnections between the summer NAO (SNAO) and climate in East Asia over the last four centuries – A tree-ring perspective." Dendrochronologia 31, no. 4 (2013): 297–310. http://dx.doi.org/10.1016/j.dendro.2012.08.004.

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17

Kamiya, Atsunori, Toru Kawada, Kenta Yamamoto, et al. "Dynamic and static baroreflex control of muscle sympathetic nerve activity (SNA) parallels that of renal and cardiac SNA during physiological change in pressure." American Journal of Physiology-Heart and Circulatory Physiology 289, no. 6 (2005): H2641—H2648. http://dx.doi.org/10.1152/ajpheart.00642.2005.

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Despite accumulated knowledge on human baroreflex control of muscle sympathetic nerve activity (SNA), whether baroreflex control of muscle SNA parallels that of other SNAs, in particular renal and cardiac SNAs, remains unclear. Using urethane and α-chloralose-anesthetized, vagotomized and aortic-denervated rabbits ( n = 10), we recorded muscle SNA from tibial nerve by microneurography, simultaneously with renal and cardiac SNAs by wire electrode. To produce a baroreflex open-loop condition, we isolated the carotid sinuses from systemic circulation and altered the intracarotid sinus pressure (C

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18

Kamiya, Atsunori, Toru Kawada, Masaki Mizuno, Shuji Shimizu, and Masaru Sugimachi. "Parallel resetting of arterial baroreflex control of renal and cardiac sympathetic nerve activities during upright tilt in rabbits." American Journal of Physiology-Heart and Circulatory Physiology 298, no. 6 (2010): H1966—H1975. http://dx.doi.org/10.1152/ajpheart.00340.2009.

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Since humans are under ceaseless orthostatic stress, the mechanisms to maintain arterial pressure (AP) against gravitational fluid shift are important. As one mechanism, it was reported that upright tilt reset baroreflex control of renal sympathetic nerve activity (SNA) to a higher SNA in anesthetized rabbits. In the present study, we tested the hypothesis that upright tilt causes a parallel resetting of baroreflex control of renal and cardiac SNAs in anesthetized rabbits. In anesthetized rabbits ( n = 8, vagotomized and aortic denervated) with 0° supine and 60° upright tilt postures, renal an

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19

Bijelić, Jelena, Dalibor Tatar, Sugato Hajra та ін. "Nanocrystalline Antiferromagnetic High-κ Dielectric Sr2NiMO6 (M = Te, W) with Double Perovskite Structure Type". Molecules 25, № 17 (2020): 3996. http://dx.doi.org/10.3390/molecules25173996.

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Double perovskites have been extensively studied in materials chemistry due to their excellent properties and novel features attributed to the coexistence of ferro/ferri/antiferro-magnetic ground state and semiconductor band gap within the same material. Double perovskites with Sr2NiMO6 (M = Te, W) structure type have been synthesized using simple, non-toxic and costless aqueous citrate sol-gel route. The reaction yielded phase-pure nanocrystalline powders of two compounds: Sr2NiWO6 (SNWO) and Sr2NiTeO6 (SNTO). According to the Rietveld refinement of powder X-ray diffraction data at room tempe

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20

Rocha, Eva, Björn E. Gunnarson, and Steffen Holzkämper. "Reconstructing Summer Precipitation with MXD Data from Pinus sylvestris Growing in the Stockholm Archipelago." Atmosphere 11, no. 8 (2020): 790. http://dx.doi.org/10.3390/atmos11080790.

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Maximum latewood density (MXD) chronologies have been widely used to reconstruct summer temperature variations. Precipitation signals inferred from MXD data are, however, rather scarce. In this study, we assess the potential of using MXD data derived from Scots pine (Pinus sylvestris L.) growing in the Stockholm archipelago (Sweden) to reconstruct past precipitation variability. In this area, slow-growing pine trees emerge on flat plateaus of bedrock outcrops with thin or absent soil layers and are, therefore, sensitive to moisture variability. A 268-year-long MXD chronology was produced, and

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21

Calvert, S. J., M. S. Longtine, S. Cotter, et al. "Studies of the dynamics of nuclear clustering in human syncytiotrophoblast." Reproduction 151, no. 6 (2016): 657–71. http://dx.doi.org/10.1530/rep-15-0544.

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AbstractSyncytial nuclear aggregates (SNAs), clusters of nuclei in the syncytiotrophoblast of the human placenta, are increased as gestation advances and in pregnancy pathologies. The origins of increased SNAs are unclear; however, a better appreciation of the mechanism may give insight into placental ageing and factors underpinning dysfunction. We developed three models to investigate whether SNA formation results from a dynamic process of nuclear movement and to generate alternative hypotheses. SNA count and size were measured in placental explants cultured over 16 days and particles release

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22

Li, Hui, Bohan Zhang, Xueguang Lu, et al. "Molecular spherical nucleic acids." Proceedings of the National Academy of Sciences 115, no. 17 (2018): 4340–44. http://dx.doi.org/10.1073/pnas.1801836115.

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Herein, we report a class of molecular spherical nucleic acid (SNA) nanostructures. These nano-sized single molecules are synthesized from T8 polyoctahedral silsesquioxane and buckminsterfullerene C60 scaffolds, modified with 8 and 12 pendant DNA strands, respectively. These conjugates have different DNA surface densities and thus exhibit different levels of nuclease resistance, cellular uptake, and gene regulation capabilities; the properties displayed by the C60 SNA conjugate are closer to those of conventional and prototypical gold nanoparticle SNAs. Importantly, the C60 SNA can serve as a

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Radovic-Moreno, Aleksandar F., Natalia Chernyak, Christopher C. Mader, et al. "Immunomodulatory spherical nucleic acids." Proceedings of the National Academy of Sciences 112, no. 13 (2015): 3892–97. http://dx.doi.org/10.1073/pnas.1502850112.

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Immunomodulatory nucleic acids have extraordinary promise for treating disease, yet clinical progress has been limited by a lack of tools to safely increase activity in patients. Immunomodulatory nucleic acids act by agonizing or antagonizing endosomal toll-like receptors (TLR3, TLR7/8, and TLR9), proteins involved in innate immune signaling. Immunomodulatory spherical nucleic acids (SNAs) that stimulate (immunostimulatory, IS-SNA) or regulate (immunoregulatory, IR-SNA) immunity by engaging TLRs have been designed, synthesized, and characterized. Compared with free oligonucleotides, IS-SNAs ex

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Sita, Timothy L., Fotini M. Kouri, Lisa A. Hurley, et al. "Dual bioluminescence and near-infrared fluorescence monitoring to evaluate spherical nucleic acid nanoconjugate activity in vivo." Proceedings of the National Academy of Sciences 114, no. 16 (2017): 4129–34. http://dx.doi.org/10.1073/pnas.1702736114.

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RNA interference (RNAi)-based gene regulation platforms have shown promise as a novel class of therapeutics for the precision treatment of cancer. Techniques in preclinical evaluation of RNAi-based nanoconjugates have yet to allow for optimization of their gene regulatory activity. We have developed spherical nucleic acids (SNAs) as a blood–brain barrier-/blood–tumor barrier-penetrating nanoconjugate to deliver small interfering (si) and micro (mi)RNAs to intracranial glioblastoma (GBM) tumor sites. To identify high-activity SNA conjugates and to determine optimal SNA treatment regimens, we de

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Stegh, Alexander. "DDIS-03. DEVELOPMENT OF A NOVEL CLASS OF cGAS AGONISTS TO TRIGGER STING PATHWAY-DEPENDENT INNATE IMMUNE RESPONSES AGAINST GLIOBLASTOMA." Neuro-Oncology 21, Supplement_6 (2019): vi65. http://dx.doi.org/10.1093/neuonc/noz175.263.

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Abstract The Stimulator of Interferon Genes (STING) pathway represents a major innate immune sensing mechanism for tumor-derived DNA. Modified cyclic dinucleotides (CDNs) that mimic the endogenous STING ligand cGAMP are currently being explored in patients with solid tumors that amenable to intratumoral delivery. Inadequate bioavailability and insufficient lipophilicity are limiting factors for clinical CDN development, in particular when consideration is given to systemic administration approaches. We have shown that the formulation of oligonucleotides into Spherical Nucleic Acid (SNA) nanost

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Clifton, Allan, and Gregory D. Webster. "An Introduction to Social Network Analysis for Personality and Social Psychologists." Social Psychological and Personality Science 8, no. 4 (2017): 442–53. http://dx.doi.org/10.1177/1948550617709114.

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Social network analysis (SNA) is a methodology for studying the connections and behavior of individuals within social groups. Despite its relevance to social and personality psychology, SNA has been underutilized in these fields. We first examine the paucity of SNA research in social and personality journals. Next we describe methodological decisions that must be made before collecting social network data, with benefits and drawbacks for each. We discuss common SNAs and give an overview of software available for SNA. We provide examples from the literature of SNA for both one-mode and two-mode

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Cohen Zilka, Gila. "E-Safety in the Use of Social Networking Apps by Children, Adolescents, and Young Adults." Interdisciplinary Journal of e-Skills and Lifelong Learning 14 (2018): 177–90. http://dx.doi.org/10.28945/4136.

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Aim/Purpose: Following the widespread use of social networking applications (SNAs) by children, adolescents, and young adults, this paper sought to examine the usage habits, sharing, and dangers involved from the perspective of the children, adolescents, and young adults. The research question was: What are the usage habits, sharing, drawbacks, and dangers of using SNAs from the perspective of children, adolescents, and young adults? Background: Safety has become a major issue and relates to a range of activities including online privacy, cyberbullying, exposure to violent content, exposure to

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28

Peña, J. C., L. Schulte, A. Badoux, M. Barriendos, and A. Barrera-Escoda. "Influence of solar forcing, climate variability and atmospheric circulation patterns on summer floods in Switzerland." Hydrology and Earth System Sciences Discussions 11, no. 12 (2014): 13843–90. http://dx.doi.org/10.5194/hessd-11-13843-2014.

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Abstract. The higher frequency of severe flood events in Switzerland in recent decades has given fresh impetus to the study of flood patterns and their possible forcing mechanisms, particularly in mountain environments. This paper presents an index of summer flood damage that considers severe and catastrophic summer floods in Switzerland between 1800 and 2009, and explores the influence of solar and climate forcings on flood frequencies. In addition, links between floods and low-frequency atmospheric circulation patterns are examined. The flood damage index provides evidence that the 1817–1851

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29

Burić, D., and G. Stanojević. "Trends and possible causes of cloudiness variability in Montenegro in the period 1961-2017." Climate Research 81 (October 8, 2020): 187–205. http://dx.doi.org/10.3354/cr01615.

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Cloudiness is an important climate parameter, and it is closely related to insolation, temperature, and precipitation. Total cloud cover (TCC) data along with the number of cloudless (CL) and overcast (OC) days from 18 stations in Montenegro during the period 1961-2017 were used to determine the seasonal trends and possible causes of cloudiness variability. The Mann-Kendall test and Sen’s slope were used for trend detection. We found statistically significant (p < 0.05 and p < 0.10) decreasing (increasing) trends in TCC (the number of CL days) in winter, spring and summer. The exception

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Patro, Katarzyna, and Maciej Haman. "Playing Reading, Using Hands: Which Activities are Linked to Number-Space Processing in Preschool Children?" Psychology of Language and Communication 21, no. 1 (2017): 325–51. http://dx.doi.org/10.1515/plc-2017-0016.

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Abstract Literate subjects from Western cultures form spatial-numerical associations (SNA) in left-to-right direction, which follows their reading habits. In preliterate children, sources of SNA directionality are more disputable. One possibility is that SNA follows children's early knowledge about text orientation. It could also reflect ipsilateral/contralateral tendencies in manual task execution. Furthermore, SNA's characteristics could differ depending on the evaluation method used. In this study, we test SNA in preliterate preschoolers using object counting, finger counting, and numerosit

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Holmes, Thomas R., and Amy S. Paller. "Gene Regulation Using Spherical Nucleic Acids to Treat Skin Disorders." Pharmaceuticals 13, no. 11 (2020): 360. http://dx.doi.org/10.3390/ph13110360.

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Spherical nucleic acids (SNAs) are nanostructures consisting of nucleic acids in a spherical configuration, often around a nanoparticle core. SNAs are advantageous as gene-regulating agents compared to conventional gene therapy owing to their low toxicity, enhanced stability, uptake by virtually any cell, and ability to penetrate the epidermal barrier. In this review we: (i) describe the production, structure and properties of SNAs; (ii) detail the mechanism of SNA uptake in keratinocytes, regulated by scavenger receptors; and (iii) report how SNAs have been topically applied and intralesional

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Yamankurt, Gokay, Robert J. Stawicki, Diana M. Posadas, Joseph Q. Nguyen, Richard W. Carthew, and Chad A. Mirkin. "The effector mechanism of siRNA spherical nucleic acids." Proceedings of the National Academy of Sciences 117, no. 3 (2020): 1312–20. http://dx.doi.org/10.1073/pnas.1915907117.

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Spherical nucleic acids (SNAs) are nanostructures formed by chemically conjugating short linear strands of oligonucleotides to a nanoparticle template. When made with modified small interfering RNA (siRNA) duplexes, SNAs act as single-entity transfection and gene silencing agents and have been used as lead therapeutic constructs in several disease models. However, the manner in which modified siRNA duplex strands that comprise the SNA lead to gene silencing is not understood. Herein, a systematic analysis of siRNA biochemistry involving SNAs shows that Dicer cleaves the modified siRNA duplex f

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33

SHEN, YUNZHU, and YONGXIANG ZHANG. "STRANGE NONCHAOTIC ATTRACTORS IN A QUASIPERIODICALLY-FORCED PIECEWISE SMOOTH SYSTEM WITH FAREY TREE." Fractals 27, no. 07 (2019): 1950118. http://dx.doi.org/10.1142/s0218348x19501184.

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The existence of strange nonchaotic attractors (SNAs) is verified in a simple quasiperiodically-forced piecewise smooth system with Farey tree. It can be seen that more and more jumping discontinuities appear on the smooth torus and the torus becomes extremely fragmented with the change of control parameter. Finally, the torus becomes an SNA with fractal property. In order to confirm the existence of SNAs in this system, we preliminarily use the estimation of the phase sensitivity exponent, estimation of the largest Lyapunov exponent and rational approximation. SNAs are further characterized b

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Zhang, Yongxiang, and Yunzhu Shen. "A New Route to Strange Nonchaotic Attractors in an Interval Map." International Journal of Bifurcation and Chaos 30, no. 04 (2020): 2050063. http://dx.doi.org/10.1142/s0218127420500637.

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We identify an unusual route to the creation of a strange nonchaotic attractor (SNA) in a quasiperiodically forced interval map. We find that the smooth quasiperiodic torus becomes nonsmooth due to the grazing bifurcation of the torus. The nonsmooth points on the torus increase more and more with the change of control parameter. Finally, the torus gets extremely fractal and becomes a SNA which is termed the grazing bifurcation route to the SNA. We characterize the SNA by maximal Lyapunov exponents and their variance, phase sensitivity exponents and power spectra. We also describe the transitio

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LI, GAOLEI, YUAN YUE, CELSO GREBOGI, DENGHUI LI, and JIANHUA XIE. "STRANGE NONCHAOTIC ATTRACTORS AND MULTISTABILITY IN A TWO-DEGREE-OF-FREEDOM QUASIPERIODICALLY FORCED VIBRO-IMPACT SYSTEM." Fractals 29, no. 04 (2021): 2150103. http://dx.doi.org/10.1142/s0218348x21501036.

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In this work, we initially study the strange nonchaotic dynamics of a two-degree-of-freedom quasiperiodically forced vibro-impact system. It is shown that strange nonchaotic attractors (SNAs) occur between two chaotic regions, but not between the quasiperiodic region and the chaotic one. Subsequently, we mainly focus on the abundant multistability in the system, especially the coexistence of SNAs and quasiperiodic attractors. Besides, the coexistence of quasiperiodic attractors of different frequencies, and the coexistence of quasiperiodic attractors and chaotic attractors are also uncovered.

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Zhang, Xu. "Dynamics of a Class of Nonautonomous Lorenz-Type Systems." International Journal of Bifurcation and Chaos 26, no. 12 (2016): 1650208. http://dx.doi.org/10.1142/s0218127416502084.

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The dynamical properties of a kind of Lorenz-type systems with time-varying parameters are studied. The time-varying ultimate bounds are estimated, and a simple method is provided to generate strange attractors, including both the strange nonchaotic attractors (SNAs) and chaotic attractors. The approach is: (i) take an autonomous system with an ultimate bound from the Lorenz family; (ii) add at least two time-varying parameters with incommensurate frequencies satisfying certain conditions; (iii) choose the proper initial position and time by numerical simulations. Three interesting examples ar

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Randeria, Pratik S., Mark A. Seeger, Xiao-Qi Wang, et al. "siRNA-based spherical nucleic acids reverse impaired wound healing in diabetic mice by ganglioside GM3 synthase knockdown." Proceedings of the National Academy of Sciences 112, no. 18 (2015): 5573–78. http://dx.doi.org/10.1073/pnas.1505951112.

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Spherical nucleic acid (SNA) gold nanoparticle conjugates (13-nm-diameter gold cores functionalized with densely packed and highly oriented nucleic acids) dispersed in Aquaphor have been shown to penetrate the epidermal barrier of both intact mouse and human skin, enter keratinocytes, and efficiently down-regulate gene targets. ganglioside-monosialic acid 3 synthase (GM3S) is a known target that is overexpressed in diabetic mice and responsible for causing insulin resistance and impeding wound healing. GM3S SNAs increase keratinocyte migration and proliferation as well as insulin and insulin-l

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Kanbar, Roy, Bruno Chapuis, Valérie Oréa, Christian Barrès, and Claude Julien. "Baroreflex control of lumbar and renal sympathetic nerve activity in conscious rats." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 295, no. 1 (2008): R8—R14. http://dx.doi.org/10.1152/ajpregu.00147.2008.

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This study compared the baroreflex control of lumbar and renal sympathetic nerve activity (SNA) in conscious rats. Arterial pressure (AP) and lumbar and renal SNA were simultaneously recorded in six freely behaving rats. Pharmacological estimates of lumbar and renal sympathetic baroreflex sensitivity (BRS) were obtained by means of the sequential intravenous administration of sodium nitroprusside and phenylephrine. Sympathetic BRS was significantly ( P < 0.05) lower for lumbar [3.0 ± 0.4 normalized units (NU)/mmHg] than for renal (7.6 ± 0.6 NU/mmHg) SNA. During a 219-min baseline period, sp

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Arulgnanam, A., Awadesh Prasad, K. Thamilmaran, and M. Daniel. "Analytical Study and Experimental Confirmation of SNA Through Poincaré Maps in a Quasiperiodically Forced Electronic Circuit." International Journal of Bifurcation and Chaos 25, no. 08 (2015): 1530020. http://dx.doi.org/10.1142/s0218127415300207.

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Quasiperiodically forced series LCR circuit with simple nonlinear element is studied analytically and experimentally. To the best of our knowledge, this is the first time that strange nonchaotic attractors (SNAs) are studied analytically. From the explicit analytical solution, the bifurcation process is shown. With a single negative conduction region of the nonlinear element two routes namely, Heagy–Hammel and fractalization routes to the birth of SNA are identified. The analytical analysis are confirmed by laboratory hardware experiments. In addition, for the first time, a detailed stroboscop

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Goldman, G. H., and N. R. Morris. "Extragenic suppressors of a dynein mutation that blocks nuclear migration in Aspergillus nidulans." Genetics 139, no. 3 (1995): 1223–32. http://dx.doi.org/10.1093/genetics/139.3.1223.

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Abstract Cytoplasmic dynein is a large molecular weight protein complex that functions as a microtubule-dependent, negative, end-directed "motor." Mutations in nudA, which encodes the heavy chain of cytoplasmic dynein, inhibit nuclear migration in Aspergillus nidulans. This paper describes the selection and characterization of extragenic suppressors of the nudA1 mutation preparatory to the identification of other proteins that interact directly or indirectly with the cytoplasmic dynein heavy chain. To facilitate future cloning of the suppressor genes, we have searched particularly for extragen

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Rizwana, R., and I. Raja Mohamed. "Investigation of Chaotic and Strange Nonchaotic Phenomena in Nonautonomous Wien-Bridge Oscillator with Diode Nonlinearity." Journal of Nonlinear Dynamics 2015 (February 15, 2015): 1–7. http://dx.doi.org/10.1155/2015/612516.

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We have studied the chaotic and strange nonchaotic phenomena of a simple quasiperiodically forced Wien bridge oscillator circuit with diode as the only nonlinearity in this electronic oscillator system responsible for various nonlinear behaviors. Both the experimental results and the numerical simulation results for their confirmation are provided to show the bifurcation process. Various measures used for the numerical confirmation of SNA are power spectrum, maximal Lyapunov exponent, path of translational variables, mean square displacement, projection of poincaré section, log-log plot, and a

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Lázaro, Sara, Francisca Fernández-Piñas, Eduardo Fernández-Valiente, Amaya Blanco-Rivero, and Francisco Leganés. "pbpB, a Gene Coding for a Putative Penicillin-Binding Protein, Is Required for Aerobic Nitrogen Fixation in the Cyanobacterium Anabaena sp. Strain PCC7120." Journal of Bacteriology 183, no. 2 (2001): 628–36. http://dx.doi.org/10.1128/jb.183.2.628-636.2001.

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ABSTRACT Transposon mutagenesis of Anabaena sp. strain PCC7120 led to the isolation of a mutant strain, SNa1, which is unable to fix nitrogen aerobically but is perfectly able to grow with combined nitrogen (i.e., nitrate). Reconstruction of the transposon mutation of SNa1 in the wild-type strain reproduced the phenotype of the original mutant. The transposon had inserted within an open reading frame whose translation product shows significant homology with a family of proteins known as high-molecular-weight penicillin-binding proteins (PBPs), which are involved in the synthesis of the peptido

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Wang, Shuya, Lei Qin, Gokay Yamankurt, et al. "Rational vaccinology with spherical nucleic acids." Proceedings of the National Academy of Sciences 116, no. 21 (2019): 10473–81. http://dx.doi.org/10.1073/pnas.1902805116.

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In the case of cancer immunotherapy, nanostructures are attractive because they can carry all of the necessary components of a vaccine, including both antigen and adjuvant. Herein, we explore how spherical nucleic acids (SNAs), an emerging class of nanotherapeutic materials, can be used to deliver peptide antigens and nucleic acid adjuvants to raise immune responses that kill cancer cells, reduce (or eliminate) tumor growth, and extend life in three established mouse tumor models. Three SNA structures that are compositionally nearly identical but structurally different markedly vary in their a

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Andrews, Lester, Parviz Hassanzadeh, G. Dana Brabson, Angelo Citra, and Matthew Neurock. "Reactions of Nitric Oxide with Sulfur Species. Infrared Spectra and Density Functional Theory Calculations for SNO, SNO+, SSNO, and SNNO in Solid Argon." Journal of Physical Chemistry 100, no. 20 (1996): 8273–79. http://dx.doi.org/10.1021/jp960043v.

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Kamiya, Atsunori, Toru Kawada, Masaki Mizuno, et al. "Baroreflex Increases Correlation and Coherence of Muscle Sympathetic Nerve Activity (SNA) with Renal and Cardiac SNAs." Journal of Physiological Sciences 56, no. 5 (2006): 325–33. http://dx.doi.org/10.2170/physiolsci.rp009006.

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Jones, Rachel. "Snap!" Nature Reviews Neuroscience 2, no. 11 (2001): 758. http://dx.doi.org/10.1038/35097528.

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Day, Kate Nace. "Snap." Law and Literature 15, no. 1 (2003): 143–58. http://dx.doi.org/10.1525/lal.2003.15.1.143.

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Leskovec, Jure, and Rok Sosič. "SNAP." ACM Transactions on Intelligent Systems and Technology 8, no. 1 (2016): 1–20. http://dx.doi.org/10.1145/2898361.

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Baker, Ann-Marie, William Cross, Kit Curtius, et al. "Evolutionary history of human colitis-associated colorectal cancer." Gut 68, no. 6 (2018): 985–95. http://dx.doi.org/10.1136/gutjnl-2018-316191.

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ObjectiveIBD confers an increased lifetime risk of developing colorectal cancer (CRC), and colitis-associated CRC (CA-CRC) is molecularly distinct from sporadic CRC (S-CRC). Here we have dissected the evolutionary history of CA-CRC using multiregion sequencing.DesignExome sequencing was performed on fresh-frozen multiple regions of carcinoma, adjacent non-cancerous mucosa and blood from 12 patients with CA-CRC (n=55 exomes), and key variants were validated with orthogonal methods. Genome-wide copy number profiling was performed using single nucleotide polymorphism arrays and low-pass whole gen

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KOBAYASHI, Mamoru. "sNan bcas pa and sNan med pa." JOURNAL OF INDIAN AND BUDDHIST STUDIES (INDOGAKU BUKKYOGAKU KENKYU) 54, no. 1 (2005): 492–86. http://dx.doi.org/10.4259/ibk.54.492.

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