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Dissertations / Theses on the topic 'Social perception. Prefrontal cortex'

Author: Grafiati

Published: 4 June 2021

Last updated: 5 February 2022

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1

Croft, Katie Elizabeth Anderson Steven W. "Exploring the role of ventromedial prefrontal cortex in human social learning a lesion study /." [Iowa City, Iowa] : University of Iowa, 2009. http://ir.uiowa.edu/etd/350.

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2

Theodoni, Panagiota. "Fluctuations in perceptual decisions : cortical microcircuit dynamics mediating alternations in conscious visual perception." Doctoral thesis, Universitat Pompeu Fabra, 2014. http://hdl.handle.net/10803/145642.

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Fluctuations in perceptual decisions emerge when our brain confronts with ambiguous sensory stimuli. For instance, our perception alternates between two conflicting images when presented dichoptically to our eyes, allowing a dissociation of the sensory stimulation from the conscious visual perception, and therefore providing a gateway to consciousness. How does the brain work when it deals with such ambiguous sensory stimuli? We addressed this question theoretically by employing a biophysically realistic attractor network, by consistently reducing it to a four- variable rate- based model

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3

Baldwin, Erin. "Humor Perception: The Contribution of Cognitive Factors." Digital Archive @ GSU, 2007. http://digitalarchive.gsu.edu/psych_diss/31.

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Most of the extant humor research has focused on humor comprehension with only a few studies investigating humor appreciation as a separate construct. The purpose of this investigation was to determine the relation between humor and underlying cognitive processes. Literature on brain injured individuals has indicated that working memory, verbal and visual-spatial reasoning, cognitive flexibility, and concept formation are related to performance on comprehension tests of humor. In this study, cognitive processes underlying both verbal and nonverbal humor were investigated in a sample of healthy

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4

Krüger, Frank. "The role of the medial prefrontal cortex in mediating social event knowledge." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät II, 2011. http://dx.doi.org/10.18452/13977.

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Zunehmend mehr Beweise aus der sozialen Neurowissenschaft deuten darauf hin, dass der mediale präfrontale Cortex (mPFC) eine entscheidende neurale Komponente in der Verarbeitung von sozialem Ereigniswissen ist. Die vorliegende Arbeit stellt eine integrative Theorie der kognitiven und neuronalen Grundlagen von sozialem Ereigniswissen vor. Die „Structural and Temporal Representation Binding“ (STRing) Theorie postuliert, dass der mPFC abstrakte dynamische summarische Repräsentationen in Form von Ereignissimulatoren speichert, die Wissen über soziale Abläufe mittles Einbinding von Regionen im post

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5

Girardi, Alessandra. "Perception of self and others in healthy ageing." Thesis, University of Edinburgh, 2013. http://hdl.handle.net/1842/7978.

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Processing information related to the self and inferring the mental state of another person is known to involve the ventromedial prefrontal cortex (VMPFC) in both younger and older adults (Stone et al., 2008; Kelley et al., 2002; Hynes et al., 2006; Ruby et al., 2009). According to the dorsolateral prefrontal (DLPF) theory of cognitive ageing, processing of the self should not be affected by healthy adult ageing as functions related to the VMPFC remain relatively preserved compared to functions related to the DLPF cortex (MacPherson et al., 2002). Similarly, no age difference should emerge in

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6

Gupta, Rupa. "The effects of ventromedial prefrontal cortex damage on interpersonal coordination in social interaction." Diss., University of Iowa, 2012. https://ir.uiowa.edu/etd/2883.

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Conversation is a highly interactive and coordinated effort between interactants. For example, interactants often mimic the behaviors and speech of one another and coordinate the timing of behaviors, or interactional synchrony. Despite being affected in certain neurological and psychiatric disorders, the neural mechanisms underlying these processes are not understood. The goal of this study is to understand the role of the ventromedial prefrontal cortex (vmPFC), an area of the brain involved in social and emotional behavio

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7

Spanò, Goffredina. "Perceptual Mnemonic Medial Temporal Lobe Function in Individuals with Down Syndrome." Thesis, The University of Arizona, 2012. http://hdl.handle.net/10150/255154.

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Behavioral data in individuals with Down syndrome (DS) and mouse models of the syndrome suggest impaired object processing. In this study we examined the component processes that may contribute to object memory deficits. A neuropsychological test battery was administered to individuals with DS (n=28), including tests targeting perirhinal cortex (PRC) and prefrontal cortex (PFC) function, tests of perception (i.e., convexity based figure ground perception), and tests of memory (object recognition and object-in-place learning). To compare to individuals with DS, the same number of typically deve

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8

Novick, Andrew Michael. "Long-term consequences of adolescent social defeat on cognition and prefrontal cortex dopamine function." Thesis, University of South Dakota, 2015. http://pqdtopen.proquest.com/#viewpdf?dispub=3714207.

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<p> Individuals who are victimized by bullying during adolescence demonstrate an increased incidence of psychiatric disorders both acutely and later in life. Many of these disorders are characterized by deficits in complex cognitive functions that are mediated by the mesocortical dopamine system. The substantial maturation of the mesocortical dopamine system during adolescence may render it particularly vulnerable to insult from psychosocial stressors such as bullying. Using a rodent model of adolescent social defeat to replicate the imbalance of power inherent in teenage bullying, it was prev

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9

Croft, Katie Elizabeth. "Exploring the role of ventromedial prefrontal cortex in human social learning: a lesion study." Diss., University of Iowa, 2009. https://ir.uiowa.edu/etd/350.

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Converging evidence suggests a critical role for the ventromedial prefrontal cortex (vmPFC) in social cognition, but its specific contribution to various aspects of social cognition, including the acquisition and updating of complex social information, is not well understood or documented via a systematic experimental approach. The primary aim of this dissertation is to determine whether the vmPFC is necessary for the integration of complex social information in order to form normal moral and social judgments about people. In the first of two studies presented here, I examined the roles of the

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10

Bel-Bahar, Tarik Stanislaw. "Cortico-limbic mechanisms of meaning making : judgments of personality and emotion from faces /." Connect to title online (ProQuest), 2008. http://proquest.umi.com/pqdweb?did=1678701141&sid=3&Fmt=2&clientId=11238&RQT=309&VName=PQD.

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Thesis (Ph. D.)--University of Oregon, 2008.<br>Typescript. Includes vita and abstract. Includes bibliographical references (leaves 188-219). Also available online in ProQuest, free to University of Oregon users.

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11

Beadle, Janelle Nicole. "The neuroanatomical basis of empathy: is empathy impaired following damage to the ventromedial prefrontal cortex?" Diss., University of Iowa, 2009. https://ir.uiowa.edu/etd/781.

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Empathy plays a crucial role in our relationships with others and enhances personal well-being. The brain areas that are critical for the experience of on-line empathy and empathic behavior are not known. The current study investigated the neural substrates of empathy through the examination of whether the ventromedial prefrontal cortex (VMPC) is critical for empathy. For the first time, on-line empathic experience and behavior were measured in patients with brain damage to the VMPC. Six patients with bilateral damage to the VMPC were case-matched on specific demographic and neuropsychological

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12

Browncross, Helen Anna. "The role of the primate frontopolar cortex in mnemonic and choice behaviour." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:2807879b-e535-474c-b884-fa4c3c5296ab.

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The role of the primate frontopolar cortex (FPC) has been investigated using human neuroimaging, lesion and disruption techniques. The results of these investigations have led to a variety of theories regarding the function of this region. It has been linked to the formation of task sets, the performance of multiple tasks, reasoning, context-specific memory (including episodic memory, prospective memory and source memory), attention to internally or externally generated information, mentalising and decision-making. It has not previously been possible to study this area using animal lesion tech

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13

Bouamrane, Mohamed Lamine. "Dysfonctionnements préfrontaux et pharmacothérapies dans des modèles murins de maladies spychiatriques." Thesis, Aix-Marseille, 2015. http://www.theses.fr/2015AIXM4106/document.

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La pathogénèse de désordres psychiatriques comme les troubles de l'humeur et la schizophrénie met en jeu des facteurs génétiques et environnementaux. La reelin, une protéine de la matrice extracellulaire et l'isolement social (IS), un stress environnemental participeraient à l'étiologie de ces maladies. Le cortex préfrontal (CPF) impliqué dans les fonctions cognitives et exécutives, présente des anomalies morpho-fonctionnelles chez les patients atteints de ces troubles. Le but de ma thèse est d'étudier l'effet de l'IS et d'une haplo-insuffisance en reelin (HIR) sur les propriétés du CPF adulte

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14

Demolliens, Marie. "Modulation de l'apprentissage par la présence des congénères : étude comportementale et électrophysiologique chez le singe." Thesis, Aix-Marseille, 2015. http://www.theses.fr/2015AIXM5047.

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À l’interface des neurosciences et de la psychologie sociale expérimentale, nos travaux explorent les bases neuronales de la « facilitation sociale » (effet facilitateur de la présence d’un congénère sur la performance) chez le singe à partir d'enregistrements électrophysiologiques unitaires dans le cortex préfrontal dorsolatéral et dans le cortex cingulaire antérieur. L'analyse de l’activité de 342 neurones liée au codage des résultats de l’action (signaux d'erreur et de succès) révèle que, dans leur grande majorité, les neurones de ces deux structures expriment une sensibilité différenciée à

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15

Smith, Ryan, Richard D. Lane, Anna Alkozei, et al. "Maintaining the feelings of others in working memory is associated with activation of the left anterior insula and left frontal-parietal control network." OXFORD UNIV PRESS, 2017. http://hdl.handle.net/10150/625065.

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The maintenance of social/emotional information in working memory (SWM/EWM) has recently been the topic of multiple neuroimaging studies. However, some studies find that SWM/EWM involves a medial frontal-parietal network while others instead find lateral frontal-parietal activations similar to studies of verbal and visuospatial WM. In this study, we asked 26 healthy volunteers to complete an EWM task designed to examine whether different cognitive strategies- maintaining emotional images, words, or feelings- might account for these discrepant results. We also examined whether differences in EW

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16

Yamawaki, Rie. "Remembering my friends: Medial prefrontal and hippocampal contributions to the self-reference effect on face memories in a social context." Kyoto University, 2018. http://hdl.handle.net/2433/231016.

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17

Koscik, Timothy Richard. "Social inference and the evolution of the human brain." Diss., University of Iowa, 2010. https://ir.uiowa.edu/etd/837.

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The evolutionary forces that led to the unprecedented expansion of the human brain and the extreme cognitive prowess possessed by humans have always attracted a great deal of attention from the scientific community. Presented here is a novel theoretical perspective, where the driving force on human brain evolution was the need for enhanced ability to infer social values of conspecifics in the face of degradation and loss of chemosensory signalling mechanisms necessary for social communication present in most mammals. The lack of chemosensory communication of biologically relevant information b

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18

Zhou, Shu. "Mécanismes centraux de la perception et de la modulation de la douleur dans le vieillissement." Thesis, Strasbourg, 2015. http://www.theses.fr/2015STRAJ062/document.

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De nombreuses études ont montré une modification de la perception de la douleur au cours du vieillissement. Cette modification s’exprime principalement par une diminution du seuil de la douleur aiguë et une augmentation de la prévalence de douleurs chroniques. Parallèlement, le vieillissement provoque des altérations cérébrales importantes, notamment dans les réseaux frontaux. Dans ce travail de thèse, nous avons étudié les mécanismes centraux, notamment les fonctions des réseaux frontaux sur la perception et la modulation de la douleur chez la personne âgée. Les résultats des expériences 1 à

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19

Bertke, Alexander. "Social Buffering By Unfamiliar Adult Males in Periadolescent Guinea Pigs: The Effects on HPA Axis Activity And Fos Induction In The Medial Prefrontal Cortex." Wright State University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=wright1559558966039455.

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20

Eriksson, Johan. "The conscious brain : Empirical investigations of the neural correlates of perceptual awareness." Doctoral thesis, Umeå : Department of Psychology, Umeå University, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1430.

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21

Isbaine, Faiçal. "Apprentissage par observation chez le singe : études comportementale et électrophysiologique." Thesis, Aix-Marseille, 2015. http://www.theses.fr/2015AIXM5052.

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L’apprentissage social améliore les performances non seulement chez l’homme et les primates non humains, mais aussi chez un grand nombre d’espèces. Chez le singe, les corrélats neuronaux de l’apprentissage individuel sont parfaitement connus, mais ceux de l’apprentissage social font cependant défaut, en partie à cause des conditions dans lesquelles il a été étudié, jusqu’à maintenant et qui n’étaient pas compatibles avec les enregistrements neuronaux. Ce travail aborde deux questions d’actualité : Les singes peuvent-ils apprendre par observation dans les conditions contraignantes de l’électrop

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22

Krüger, Frank Verfasser], Elke van der [Akademischer Betreuer] Meer, Jean [Akademischer Betreuer] [Decety, and Arno [Akademischer Betreuer] Villringer. "The role of the medial prefrontal cortex in mediating social event knowledge / Frank Krüger. Gutachter: Elke van der Meer ; Jean Decety ; Arno Villringer." Berlin : Humboldt Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät II, 2011. http://d-nb.info/101504638X/34.

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23

Faria, Vanda. "Mind really does matter : The Neurobiology of Placebo-induced Anxiety Relief in Social Anxiety Disorder." Doctoral thesis, Uppsala universitet, Institutionen för psykologi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-181548.

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The placebo effect, a beneficial effect attributable to a treatment containing no specific properties for the condition being treated, has been demonstrated in a variety of medical conditions. This thesis includes four studies aimed at increasing our knowledge on the neurobiology of placebo. Study I, a review of the placebo neuroimaging literature, suggested that the anterior cingulate cortex (ACC) may be a common site of action for placebo responses. However, because placebo neuroimaging studies in clinical disorders are largely lacking, the clinical relevance of this needs further clarificat

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24

Watanasriyakul, Withayapon. "Social Buffering By Unfamiliar Adult Males In Preweaning Guinea Pigs (Cavia Pocellus): The Effects On HPA Activity And Fos Induction In The Medial Prefrontal Cortex." Wright State University / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=wright1459270309.

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25

Tsukagoshi, Chihiro. "Neural activity in the prelimbic and infralimbic cortices of freely moving rats during social interaction: Effect of isolation rearing." Kyoto University, 2018. http://hdl.handle.net/2433/232148.

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26

Price, Iris L. "Visuospatial reasoning in toddlers a correlational study of door task performance /." Amherst, Mass. : University of Massachusetts Amherst, 2009. http://scholarworks.umass.edu/open_access_dissertations/63/.

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27

Psomiades, Marion. "Altérations cérébrales structurales et fonctionnelles spécifiques des hallucinations auditives résistantes chez les patients atteints de schizophrénie." Thesis, Lyon, 2017. http://www.theses.fr/2017LYSE1218.

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Les hallucinations auditives (HA) sont présentes chez 70% à 80% des patients atteints de schizophrénie et sont résistantes aux traitements pharmacologiques dans environs 25% cas. Ces symptômes induisent une détresse importante chez les sujets et grèvent le pronostic. Dans ce travail, nous avons mis en avant des altérations cérébrales spécifiques aux HA chez des patients atteints de schizophrénie. Dans une première étude, en utilisant la méthode de DTI, nous avons montré que les patients atteints de schizophrénie avec HA ont une intégrité du faisceau arqué, supérieure à celle mesurée chez des p

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Thyberg, Joel. "Dehumanization in the brain." Thesis, Högskolan i Skövde, Institutionen för biovetenskap, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-17727.

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Dehumanization is a process whereby people fail to view others as human beings. Instead, the others are perceived as nonhuman animals or objects, unworthy of the same moral treatment. Dehumanization has previously been studied in a variety of different scholarly domains without adhering to a uniform theoretical framework. This literature review contrasts research on fully humanized perception, with research on dehumanized perception, and proposes neural areas which are likely to be involved. Not every aspect of dehumanization can be understood at the neurological level. To understand what fact

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29

Xu, Yang. "Cortical spatiotemporal plasticity in visual category learning." Research Showcase @ CMU, 2013. http://repository.cmu.edu/dissertations/272.

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Central to human intelligence, visual categorization is a skill that is both remarkably fast and accurate. Although there have been numerous studies in primates regarding how information flows in inferiortemporal (ITC) and prefrontal (PFC) cortices during online discrimination of visual categories, there has been little comparable research on the human cortex. To bridge this gap, this thesis explores how visual categories emerge in prefrontal cortex and the ventral stream, which is the human homologue of ITC. In particular, cortical spatiotemporal plasticity in visual category learning was inv

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Centenaro, Lígia Aline. "Provocação social e comportamento agressivo : envolvimento dos receptores 5-HT1A e 5-HT1B no córtex pré-frontal." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2008. http://hdl.handle.net/10183/13070.

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A provocação social é um método utilizado em animais de laboratório para a indução de elevados níveis de agressividade, produzindo padrões comportamentais semelhantes ao de indivíduos violentos. Estudos prévios utilizando drogas que atuam seletivamente sobre os receptores 5-HT1A e 5-HT1B demonstraram uma redução pronunciada no comportamento agressivo. Um dos mais importantes sítios de ação para esses agentes serotonérgicos é o córtex pré-frontal, uma região cerebral particularmente relevante no controle inibitório da agressividade e da impulsividade. O objetivo do presente estudo foi verificar

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31

Chabout, Jonathan. "Rôle(s) des motivations naturelles dans la prise décision : bases neurobiologiques et comportementales." Phd thesis, Université Paris Sud - Paris XI, 2012. http://tel.archives-ouvertes.fr/tel-00817491.

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La prise de décision est un processus indispensable et vital pour les mammifères. Elle permet à l'individu de s'adapter aux changements qui s'opèrent dans son environnement et résulte de l'intégration d'informations sensorielles, émotionnelles, motivationnelles et exécutives (qui peuvent être internes ou externes à l'individu). Des études, à la fois chez le sujet humain (sujet sain, patients cérébrolésés ou atteints de pathologies psychiatriques), et sur les modèles animaux singe, rats ou souris, ont permis d'identifier le cortex préfrontal comme acteur crucial dans ces processus exécutifs com

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32

Besle, Julien. "Interactions audiovisuelles dans le cortex auditif chez l'homme : approches électrophysiologique et comportementale." Phd thesis, Université Lumière - Lyon II, 2007. http://tel.archives-ouvertes.fr/tel-00161510.

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Nous avons étudié, par des mesures comportementales et électrophysiologiques (PE), les interactions audiovisuelles (AV) mises en jeu dans deux types de processus essentiellement auditifs : la perception de la parole, et les représentations en mémoire sensorielle auditive (MSA).<br />Concernant la parole, nous avons montré que la vision des mouvements labiaux accélère la discrimination phonologique de syllabes. Cette facilitation comportementale était associée à la fois à une activation des cortex auditifs (surtout secondaires) par les mouvements de lèvres, visible sur les PE intracérébraux che

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33

Dawson, Gabriel M. "Relationship Between Factors Associated with Toxic Stress and Child Behavior in the Dental Office." The Ohio State University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=osu1469537364.

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Bosaipo, Nayanne Beckmann. "Padrão da atividade locomotora e expressão de EAAC1 e GLT1 no córtex pré-frontal e entorrinal de ratos criados em isolamento a partir do desmame." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/59/59134/tde-18092012-162629/.

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O estresse por isolamento social aplicado em ratos a partir do desmame e mantido durante o desenvolvimento encefálico tem sido utilizado como um modelo experimental de desordens psiquiátricas como a esquizofrenia. Tem sido demonstrado que o isolamento induz alterações morfológicas, comportamentais (como hiperatividade em um novo ambiente) e neuroquímicas semelhantes àquelas que ocorrem em humanos esquizofrênicos. Evidências sugerem que as sinapses glutamatérgicas sejam o sitio primário das anormalidades que ocorrem na esquizofrenia, sendo as alterações dopaminérgicas secundárias às glutamatérg

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35

Stein, Dirson João. "Efeito da microinjeção do agonista dos receptores 5-HT1A, F15599, na região ventro-orbital do córtex pré-frontal no comportamento agressivo de camundongos machos submetidos à provocação social." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2012. http://hdl.handle.net/10183/60940.

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O sistema serotoninérgico há muito tempo vem sendo relacionado ao comportamento agressivo e particularmente o subtipo de receptor 5-HT1A está envolvido na modulação da agressividade. Estudos prévios utilizando agonistas que atuam seletivamente sobre estes receptores demonstraram tanto redução como aumento da agressão. Sabe-se que estes receptores são encontrados em diversas regiões encefálicas onde atuam como auto e heteroreceptores, apresentando diferentes funções, dependendo de sua localização. Heteroreceptores 5-HT1A, além de outras regiões, são encontrados no córtex pré-frontal, uma região

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Hok, Vincent. "Bases neurales des comportements orientés vers un but : étude des corrélats de l'activité unitaire préfrontale et hippocampique dans une tâche de navigation." Toulouse 3, 2007. http://thesesups.ups-tlse.fr/174/.

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L'hippocampe est aujourd'hui reconnu pour jouer un rôle majeur dans le traitement des informations spatiales. Bien que son rôle ne se limite pas simplement à ce type de traitement, la présence de cellules de lieu, neurones déchargeant lorsque l'animal occupe certaines localisations spatiales, a suscité nombre d'études, visant à déterminer la nature de la représentation spatiale au sein de cette structure. Néanmoins, il n'existe pas de consensus sur l'implication de l'hippocampe dans la genèse des trajets de navigation ou dans le codage des buts spatiaux. D'autre part, du fait de son rôle proba

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Cholvin, Thibault. "Rôle d'un circuit hippocampo-cortico-thalamique dans les processus de mémoire spatiale chez le rat." Thesis, Strasbourg, 2014. http://www.theses.fr/2014STRAJ044/document.

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Cette thèse avait pour objectif d’étudier le rôle du circuit composé de l’hippocampe (Hip), du cortex préfrontal médian (mPFC) et des noyaux reuniens et rhomboïde (ReRh) du thalamus dans les processus cognitifs qui sous-tendent la mémoire spatiale chez le Rat. Nous avons montré que les noyaux ReRh pourraient être impliqués dans la consolidation systémique, mécanisme nécessaire à la persistance des souvenirs et nécessitant un dialogue hippocampo-cortical. Nous avons mis en évidence que l’activité neuronale du mPFC durant le rappel d’une mémoire ancienne dépend des noyaux ReRh, ainsi que l’impli

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Adams, Geoffrey Keith. "Foraging for Information in the Prefrontal Cortex." Diss., 2014. http://hdl.handle.net/10161/9428.

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<p>The ability to monitor, learn from, and respond to social information is essential for many highly social animals, including humans. Deficits to this capacity are associated with numerous psychopathologies, including autism spectrum disorders, social anxiety disorder, and schizophrenia. To understand the neural mechanisms supporting social information seeking behavior requires understanding this behavior in its natural context, and presenting animals with species-appropriate stimuli that will elicit the behavior in the laboratory. In this dissertation, I describe a novel behavioral parad

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"The effects of BMS-204352, an activator of voltage-gated potassium channels, in the infralimbic cortex of the Fmr1 knockout mouse, an animal model of fragile X syndrome." Tulane University, 2020.

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archives@tulane.edu<br>Autism spectrum disorders (ASD) are commonly characterized by abnormal social behaviors. Fragile X syndrome (FXS) is the most common inherited intellectual disability in humans and the most common single-gene cause of ASD symptoms. FXS is caused by the loss or malfunction of the fragile X mental retardation protein (FMRP), an mRNA-binding protein that regulates numerous synaptic proteins, both translationally and through direct protein-protein interactions. One direct-binding target is the large-conductance potassium (BK) channel. BK channels have been shown to be hypoac

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Spence, John Paul. "Nf1-DEFICIENT MICE DISPLAY SOCIAL LEARNING DEFICITS THAT ARE RESCUED BY THE DELETION OF PAK1 GENE." Thesis, 2011. http://hdl.handle.net/1805/2521.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>Neurofibromatosis type 1 (NF1) is a neurocutaneous disorder that affects roughly 1 in 3500 individuals. In addition to physical features (e.g., neurofibromas), developmental disorders are also common that can affect cognition, learning, attention and social function. The NF1 gene encodes neurofibromin, a GTPase activating protein (GAP)-like protein that negatively regulates Ras GTPase activation. Mutation at the NF1 locus increases the output of MAPK and PI3K signal transduction from the cellular membrane to the nucleus. Similar to h

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Hughes, Brent Laurence 1981. "Using the neural level of analysis to understand the computational underpinnings of positivity biases in self-evaluation." Thesis, 2012. http://hdl.handle.net/2152/ETD-UT-2012-05-5297.

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Decades of research have demonstrated that people sometimes provide self-evaluations that emphasize their most flattering qualities. Different theoretical accounts have been offered to explain the mechanisms underlying positively-biased self-evaluation. Some researchers theorize that positively-biased self-evaluations arise from a self-protection motivation because positivity biases increase in situations of heightened self-esteem threat. Alternative views question whether self-protection motivation is a necessary or even dominant source of positivity bias by demonstrating that positively-bias

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Araya-Callís, Carolina. "Modulation of gene expression by chronic stress in astroglia in hippocampus and prefrontal cortex of the rat." Doctoral thesis, 2012. http://hdl.handle.net/11858/00-1735-0000-000D-EF5A-6.

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Murmu, Reena Priti [Verfasser]. "Refinement of neuronal networks in the rodent prefrontal cortex and hippocampus: critical impact of early and late social experiences / von Reena Prity Murmu." 2008. http://d-nb.info/988206161/34.

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Franco, Lara Oliveira. "Long-term impact of early life stress on adult social behavior and prefrontal cortical circuits." Doctoral thesis, 2018. http://hdl.handle.net/10316/87415.

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Tese de Doutoramento em Biologia Experimental e Biomedicina, no ramo de Neurociências e Doença, apresentada ao Instituto de Investigação Interdisciplinar da Universidade de Coimbra<br>Prolonged exposure to stressful conditions in early life imparts changes to physiology and health and may trigger or exacerbate neuropsychiatric disorders. Overt dysfunction in sociability is also a hallmark of disorders such as autism spectrum disorder (ASD) and schizophrenia. Likewise, abnormal social interaction in otherwise healthy individuals is itself a trigger for mental health disorders. In addition, for

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Reis, Tiago João dos Santos. "The role of cortico-striatal circuits in social hierarchies." Master's thesis, 2017. http://hdl.handle.net/10316/82911.

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Dissertação de Mestrado em Biologia Celular e Molecular apresentada à Faculdade de Ciências e Tecnologia<br>Na natureza, animais que vivem em grupo envolvem-se em competições por dominância, levando à formação de uma hierarquia. Esta hierarquia social permite que alguns indivíduos (de maior estatuto) ganhem prioridade de acesso a alimentos, seleção de parceiros e lugares de repouso, levando a uma redução tanto no número como na intensidade de conflitos. Estudos neurológicos recentes, usando técnicas de imagiologia, começaram a elucidar os fundamentos neuronais da formação da hierarquia social,

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Sampaio, José Pedro Pinto. "Optogenetic modulation of corticoestriatal activity for the regulation of social dominance." Master's thesis, 2018. http://hdl.handle.net/10316/86141.

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Dissertação de Mestrado em Biologia Celular e Molecular apresentada à Faculdade de Ciências e Tecnologia<br>Social hierarchies can be understood as a form of dominance, essential for animal species that live under communal systems, allowing the allocation of resources and assignment of responsibilities according to skill set, while also increasing social motivation and maximizing the group’s survival odds. Studying social hierarchies in a laboratory setting normally resorts to rodents, which naturally possess a distinct set of dominance behaviors. Laboratory mice, grown and cohabiting within t

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Janetsian, Sarine Sona. "Temporally distinct impairments in cognitive function following a sensitizing regimen of methamphetamine." Thesis, 2014. http://hdl.handle.net/1805/4843.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>Methamphetamine (MA) is a widely abused psychostimulant that has been shown to evoke an array of neurobiological abnormalities and cognitive deficits in humans and in rodent models (Marshall & O'Dell, 2012). Alterations in cognitive function after repeated drug use may lead to impaired decision-making, a lack of behavioral control, and ultimately the inability to abstain from drug use. Human studies have shown that alterations in neurobiology resulting from prolonged MA use may lead to a number of cognitive deficits, including impair

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