To see the other types of publications on this topic, follow the link: Sod line.

Journal articles on the topic 'Sod line'

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Sod line.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Lee, Dae Geon, Sang In Park, Su Jin Kang, et al. "IN VITRO ANTIOXIDANT AND ANTI-ADIPOGENIC EFFECTS OF SLENDESTATM, STANDARD POTATO EXTRACTS CONTAINS 5% PROTEASE INHIBITOR II." African Journal of Traditional, Complementary and Alternative Medicines 13, no. 2 (2016): 164–75. http://dx.doi.org/10.21010/ajtcam.v13i2.20.

Full text
Abstract:
Background: The objective of present study is to observe the anti-adipogenic effects of SlenestaTM (SLD), a standard potato protein extracts containing 5% potato protease inhibitor II (PI2) on the 3T3-L1 preadipocytes which are able to differentiate into mature adipocytes and accumulate lipids, as an obesity model with cytotoxicity and antioxidant effects. 
 Materials and Methods: The cytotoxicity of SLD was observed against 3T3-L1 pre-adipocyte cell line by MTT assay, and also anti-adipogenic effects were observed through lipid accumulation assay during 3T3-L1 differentiation as comparin
APA, Harvard, Vancouver, ISO, and other styles
2

Shao, Ying, Zhongli Chen, and Lingling Wu. "Oxidative Stress Effects of Soluble Sulfide on Human Hepatocyte Cell Line LO2." International Journal of Environmental Research and Public Health 16, no. 9 (2019): 1662. http://dx.doi.org/10.3390/ijerph16091662.

Full text
Abstract:
Soluble sulfide is well known for its toxicity and corrosion for hundreds of years. However, recent studies have demonstrated that hydrogen sulfide (H2S)—a novel gasotransmitter—supports a critical role during neuromodulation, cell proliferation, and cardioprotection for organisms. In particular, soluble sulfide plays multifaceted signaling functions in mammals during oxidative stress processes. However, the specific molecular regulation of soluble sulfide during oxidative stress remains unclear. In this study, Na2S was implemented as a soluble sulfide donor to expose LO2 cells. The 3-(4,5-dim
APA, Harvard, Vancouver, ISO, and other styles
3

Březinová Belcredi, Natálie, and Kateřina Vaculová. "Superoxide DismutasE in Spring Barley Caryopses." Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis 64, no. 2 (2016): 411–16. http://dx.doi.org/10.11118/actaun201664020411.

Full text
Abstract:
Superoxide dismutase (SOD) activity was determined in caryopses of spring barley grown in field trials in 2004–2006. A total set under study included five malting varieties with hulled grain, three waxy hull-less and hulled varieties (of US origin), seven lines formed by crossing of the above given varieties and four hull-less lines of Czech origin. SOD activity was determined by a modified method using a Ransod diagnostic kit (RANDOX). The method employs xanthine and xanthine oxidase to generate superoxide radicals which react with 2-(4-iodophenyl)-3-(4-nitrophenol)-5-phenyltetrazolium chlori
APA, Harvard, Vancouver, ISO, and other styles
4

Belcrediová, Natálie, Jaroslava Ehrenbergerová, and Pavla Havlová. "Enzyme superoxide dismutase in grain of barley and malt." Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis 54, no. 2 (2006): 7–14. http://dx.doi.org/10.11118/actaun200654020007.

Full text
Abstract:
The aim of the work was modification of superoxide dismutase enzyme (SOD, EC 1.15.1.1) activity analysis in barley grain and identical malts with using of the Ransod set. This set from company Randox were used for enzyme determination in blood samples. This method employs xanthine and xanthine oxidase to generate superoxide radicals, which react with tetrazolium chloride to form a red formazan dye. SOD is classified as natural antioxidants and enzyme plays a significant role at detoxication of products of molecular oxygen degradation. The largest rate of SOD occurs in embryo of barley grain. I
APA, Harvard, Vancouver, ISO, and other styles
5

FRANK, Stefan, Heiko KÄMPFER, Maurizio PODDA, Roland KAUFMANN, and Josef PFEILSCHIFTER. "Identification of copper/zinc superoxide dismutase as a nitric oxide-regulated gene in human (HaCaT) keratinocytes: implications for keratinocyte proliferation." Biochemical Journal 346, no. 3 (2000): 719–28. http://dx.doi.org/10.1042/bj3460719.

Full text
Abstract:
Recent studies have demonstrated an induction of expression of inducible nitric oxide synthase that is associated with several inflammatory diseases of the skin. To define the mechanisms of action of nitric oxide (NO) in the skin, we attempted to identify genes that are regulated by NO in keratinocytes. Using the human keratinocyte cell line HaCaT as a model system, we identified a Cu/Zn superoxide dismutase (SOD) that was strongly induced by high concentrations (500 μM) of NO-donating agents {S-nitrosoglutathione, sodium nitroprusside and (Z)-1-[2-(2-aminoethyl)-N-(2-ammonioethyl)amino]diazen
APA, Harvard, Vancouver, ISO, and other styles
6

Brady, Todd C., Ling-Yi Chang, Brian J. Day та James D. Crapo. "Extracellular superoxide dismutase is upregulated with inducible nitric oxide synthase after NF-κB activation". American Journal of Physiology-Lung Cellular and Molecular Physiology 273, № 5 (1997): L1002—L1006. http://dx.doi.org/10.1152/ajplung.1997.273.5.l1002.

Full text
Abstract:
Inflammatory cytokines have been shown to upregulate secretion of the antioxidant enzyme extracellular superoxide dismutase (EC-SOD) in dermal fibroblasts and, in other cells, to stimulate production of nitric oxide (⋅ NO). Because superoxide rapidly scavenges ⋅ NO, forming the injurious peroxynitrite anion (OONO−), we hypothesize that stimulated cells upregulate EC-SOD expression concurrently with ⋅ NO release. To test for coregulation of EC-SOD and ⋅ NO within the same cell, the timing of inducible nitric oxide synthase (iNOS) and EC-SOD transcription was measured after exposure of a rat typ
APA, Harvard, Vancouver, ISO, and other styles
7

Kim, Young-Min, and Won-Sook Seo. "Expression of Cu/Zn SOD according to H2O2in Hepatoma cell line." Journal of Life Science 17, no. 2 (2007): 230–34. http://dx.doi.org/10.5352/jls.2007.17.2.230.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Habas, Khaled, and Lijun Shang. "Silver Nanoparticle-Mediated Cellular Responses in Human Keratinocyte Cell Line HaCaT in Vitro." Nanoscale Reports 2, no. 2 (2019): 1–9. http://dx.doi.org/10.26524/nr1921.

Full text
Abstract:
The interactions between cells and nanoparticles has been the focus of recent research in the area. The effects of AgNPs on skin cell lines for further potential biological applications are highlighted. This study aimed to investigate the mechanism of cytotoxic and genotoxic effects of AgNPs nanoparticles on human skin keratinocytes (HaCaT). Genocytotoxic effects of AgNPs was assessed using changes in various cellular parameters of HaCaT cells involving viability, superoxide anion radical production, lactate dehydrogenase release and the levels of the antioxidant enzymes, namely, Catalase, Glu
APA, Harvard, Vancouver, ISO, and other styles
9

Korfi, Faranak, Hossein Javid, Reza Assaran Darban, and Seyed Isaac Hashemy. "The Effect of SP/NK1R on the Expression and Activity of Catalase and Superoxide Dismutase in Glioblastoma Cancer Cells." Biochemistry Research International 2021 (April 21, 2021): 1–8. http://dx.doi.org/10.1155/2021/6620708.

Full text
Abstract:
Introduction. Glioblastoma is the most malignant brain tumor with different therapeutic protocols, including surgery, radiotherapy, and chemotherapy. Substance P (SP), a peptide released by sensory nerves, increases cellular excitability by activating the neurokinin-1 receptor (NK1R) in several human tumor cells. Aprepitant is a potent and long-lasting NK1R antagonist, considered a new agent for inhibiting proliferation and induction of apoptosis in malignant cells. This study aimed to evaluate the effects of the SP/NK1R system on the expression and activity of catalase and superoxide dismutas
APA, Harvard, Vancouver, ISO, and other styles
10

Kukavica, Biljana, M. F. Quartacci, Sonja Veljovic-Jovanovic, and Flavia Navari-Izzo. "Lipid composition of pea (Pisum sativum L.) and maize (Zea mays L.) root plasma membrane and membrane-bound peroxidase and superoxide dismutase." Archives of Biological Sciences 59, no. 4 (2007): 295–302. http://dx.doi.org/10.2298/abs0704295k.

Full text
Abstract:
Plasma membrane was isolated from roots of pea and maize plants and used to analyze POD and SOD isoforms, as well as lipid composition. Among lipids, phospholipids were the main lipid class, with phosphatidylcho?line being the most abundant individual component in both pea and maize plasma membranes. Significant differences between the two plant species were found in the contents of cerebrosides, free sterols, and steryl glycosides. Most maize POD isoforms were with neutral and anionic pI values, but the opposite was observed in pea. While both anionic and cationic SOD isoforms were isolated f
APA, Harvard, Vancouver, ISO, and other styles
11

Meca, Andreea-Daniela, Adina Turcu-Stiolica, Elena Camelia Stanciulescu, et al. "Variations of Serum Oxidative Stress Biomarkers under First-Line Antituberculosis Treatment: A Pilot Study." Journal of Personalized Medicine 11, no. 2 (2021): 112. http://dx.doi.org/10.3390/jpm11020112.

Full text
Abstract:
Tuberculosis (TB) is one of the highest infectious burdens worldwide, and pathogenesis is yet incompletely elucidated. Bacilli dissemination is due to poor antioxidant defense mechanisms and intensified oxidative stress. There are few recent studies that analyzed and compared free radicals or antioxidant status before and after anti-TB treatment. Hence, the present study underlines the need to identify oxidative stress as it could be a useful tool in TB monitorisation. Thirty newly diagnosed patients with pulmonary TB were included after signing an informed consent. Blood was collected before
APA, Harvard, Vancouver, ISO, and other styles
12

Shin, Hwa Kyoung, Jeong Hyun Lee, Chi Dae Kim, Yong Ki Kim, Jae Yong Hong, and Ki Whan Hong. "Prevention of Impairment of Cerebral Blood Flow Autoregulation during Acute Stage of Subarachnoid Hemorrhage by Gene Transfer of Cu/Zn SOD-1 to Cerebral Vessels." Journal of Cerebral Blood Flow & Metabolism 23, no. 1 (2003): 111–20. http://dx.doi.org/10.1097/01.wcb.0000036561.60552.63.

Full text
Abstract:
The present study determined whether gene transfer of human copper/zinc superoxide dismutase-1 (Cu/Zn SOD-1) prevented the autoregulatory impairment of CBF induced by subarachnoid hemorrhage (SAH). After application of recombinant adenovirus (100 μL of 1 × 1010 pfu/mL, intracisternally) encoding human Cu/Zn SOD-1 3 days before experiments, Cu/Zn SOD-1 activity significantly increased in association with increase in Cu/Zn SOD-1 mRNA and protein expression in the cerebral vasculature of both sham-operated and SAH rats as determined by reverse transcriptase-polymerase chain reaction, Western blot
APA, Harvard, Vancouver, ISO, and other styles
13

Chen, Ya, Hua Wu, Zhaodong Hao, et al. "The Identification and Expression Analysis of the Liriodendron chinense (Hemsl.) Sarg. SOD Gene Family." Forests 14, no. 3 (2023): 628. http://dx.doi.org/10.3390/f14030628.

Full text
Abstract:
Superoxide dismutase (oxide dismutase) is an enzyme synthesized via the expression of SOD-related genes. It is the first line of defense against oxygen free radicals, and it widely exists in the cytoplasm, chloroplasts, and mitochondria. However, the SOD gene family of woody plant Liriodendron chinense has not been studied. To reveal the potential role of SOD genes, we systematically identified and analyzed the SOD gene family of L. chinense, and investigated the transcriptional responses of LcSOD genes to several abiotic stresses, including cold, heat, and drought. A total of eight SOD genes
APA, Harvard, Vancouver, ISO, and other styles
14

Rerkshanandana, Pichayut, Xiaotong Zhao, Yu Xiong, et al. "Hemoglobin in Submicron Particles (HbMPs) Is Stabilized Against Oxidation." Antioxidants 13, no. 12 (2024): 1477. https://doi.org/10.3390/antiox13121477.

Full text
Abstract:
Superoxide dismutase (SOD) and Catalase (CAT) play a crucial role as the first line of defense antioxidant enzymes in a living cell. These enzymes neutralize the superoxide anion from the autooxidation of oxyhemoglobin (Oxy-Hb) and convert hydrogen peroxides into water and molecular oxygen. In this study, we fabricated hemoglobin submicron particles (HbMPs) using the Coprecipitation Crosslinking Dissolution (CCD) technique and incorporating first-line antioxidant enzymes (CAT, SOD) and second-line antioxidant (ascorbic acid, Vit. C) to investigate a protective effect of modified HbMPs via cycl
APA, Harvard, Vancouver, ISO, and other styles
15

Muhammad Ajib Nuzula, Mohamad Isa, Juhairina, Haryati, Isa Ansori, and Erna Kusumawardhani. "EFFECT OF VIRGIN COCONUT OIL SUPPLEMENTATION ON AFB SPUTUM CONVERSION RATE, SOD, AND BMI LEVELS IN PULMONARY TUBERCULOSIS PATIENTS." Majalah Biomorfologi 34, no. 2 (2024): 102–13. http://dx.doi.org/10.20473/mbiom.v34i2.2024.102-113.

Full text
Abstract:
Highlights 1. VCO can accelerate AFB sputum conversion in tuberculosis infection. 2. VCO can decrease SOD levels as a marker of inflammation. Abstract Background: Pulmonary tuberculosis has the potential to raise illness and death rates on a global scale significantly. A low sputum conversion rate for acid-fast bacilli (AFB) and malnutrition are indicators of failure in pulmonary TB treatment. Virgin coconut oil (VCO) contains lauric acid and has antibacterial, antioxidant, and anti-inflammatory effects. Objective: This study aimed to examine the effect of VCO supplementation on sputum AFB con
APA, Harvard, Vancouver, ISO, and other styles
16

Bogdanovic, Visnja, Karmen Stankov, Aleksandra Nikolic, et al. "The influence of fullerenol on antioxidative enzyme activity in irradiated human erythroleukemic cell line (K562)." Chemical Industry 61, no. 3 (2007): 164–66. http://dx.doi.org/10.2298/hemind0703164b.

Full text
Abstract:
Cell culture K562 samples were treated with fullerenol (C6o(OH)24) at a concentration of 10 nmol/mL and thereafter irradiated with X-rays (24Gy). The activity of gamma-glutamyltransfrease (?-GT), total superoxide-dismutase (SOD) and glutathion-peroxidase (GSH-Px) was determined 1, 24 and 48 hours after irradiation. Irradiation induces an increase in the activity of all the investigated enzymes. Fullerenol in the applied dose decreased the ?-GT activity 24 and 48 h after irradiation. The total SOD activity is increased in both pretreated groups except in the iradiated group at the 48th hour. Tr
APA, Harvard, Vancouver, ISO, and other styles
17

Douglass, Nicola, Henry Munyanduki, Ruzaiq Omar, et al. "Influence of the Viral Superoxide Dismutase (SOD) Homologue on Lumpy Skin Disease Virus (LSDV) Growth, Histopathology and Pathogenicity." Vaccines 8, no. 4 (2020): 664. http://dx.doi.org/10.3390/vaccines8040664.

Full text
Abstract:
Lumpy skin disease is an important economic disease of cattle that is controlled by vaccination. This paper presents an investigation into the role of the lumpy skin disease virus (LSDV) superoxide dismutase (SOD) homologue on growth and histopathology of the virus both in vitro and in vivo. SOD homologue knock-out and knock-in recombinants (nLSDV∆SOD-UCT and nLSDVSODis-UCT, respectively) were constructed and compared to the Neethling vaccine (nLSDV) for growth in a permissive bovine cell line as well as on fertilized chick chorioallantoic membranes (CAMs). The infected CAMs were scored for hi
APA, Harvard, Vancouver, ISO, and other styles
18

Pluthero, F. G., M. Shreeve, D. Eskinazi, et al. "Purification of an inhibitor of erythroid progenitor cell cycling and antagonist to interleukin 3 from mouse marrow cell supernatants and its identification as cytosolic superoxide dismutase." Journal of Cell Biology 111, no. 3 (1990): 1217–23. http://dx.doi.org/10.1083/jcb.111.3.1217.

Full text
Abstract:
We have isolated a protein from media conditioned by a murine marrow-derived cell line (PB6) and from mouse marrow supernatants that antagonizes interleukin 3-dependent proliferation of cells in culture and reversibly inhibits DNA synthesis of erythroid progenitor cells (BFU-E) in vitro. This protein, p16 (monomer Mr = 16 kD on SDS-PAGE), was purified to homogeneity and amino acid sequencing of a polypeptide fragment yielded a sequence identical to that of murine cytosolic Cu,Zn-containing superoxide dismutase (SOD). The identification of p16 as SOD was confirmed by the detection of SOD enzyma
APA, Harvard, Vancouver, ISO, and other styles
19

Kamatani, Takaaki, Tetsuya Yamamoto, Kazunori Yoneda, and Tokio Osaki. "Polymorphic mutations of the Mn-SOD gene in intact human lymphocytes and oral squamous cell carcinoma cell lines." Biochemistry and Cell Biology 81, no. 1 (2003): 43–50. http://dx.doi.org/10.1139/o03-020.

Full text
Abstract:
Mutations of the superoxide dismutase (SOD) genes are associated with neoplastic and non-neoplastic diseases. However, the existence of polymorphic mutations of manganese SOD (Mn-SOD) has not been explored in squamous cell carcinoma (SCC) cells or in normal cells. In the present study, we examined mutations in the 5' flanking region of the Mn-SOD gene and Mn-SOD mRNA using 10 human oral SCC (OSC) cell lines and intact lymphocytes obtained from 10 healthy donors and one patient with OSC. The polymerase chain reaction products of DNA obtained from lymphocytes revealed insertions at many sites (–
APA, Harvard, Vancouver, ISO, and other styles
20

Min, Dongsoo, Hyunok Kim, Leejin Park, et al. "Amelioration of Diabetic Neuropathy by TAT-Mediated Enhanced Delivery of Metallothionein and SOD." Endocrinology 153, no. 1 (2012): 81–91. http://dx.doi.org/10.1210/en.2011-1639.

Full text
Abstract:
Because diabetic neuropathy (DN) appears to result from oxidative stress in neuronal tissues, antioxidant treatment should counteract the condition. Metallothionein (MT) and superoxide dismutase (SOD) are free-radical scavengers, but their ability to cross biological membranes is limited. Applying cell penetrating peptide technologies, we made Tat-MT and Tat-SOD constructs and tested their ability to protect PC12 cells, as surrogates of peripheral nerve cells, from various forms of oxidative damage. Tat-MT and Tat-SOD were successfully delivered to PC12 cells, and the intracellular activities
APA, Harvard, Vancouver, ISO, and other styles
21

Slos, Stefanie, Marjan De Block, and Robby Stoks. "Autotomy reduces immune function and antioxidant defence." Biology Letters 5, no. 1 (2008): 90–92. http://dx.doi.org/10.1098/rsbl.2008.0501.

Full text
Abstract:
Costs of autotomy, an antipredator defence, are typically explained by impaired mobility; yet physiologically mediated costs may also play a role. Given the resemblance to wounding, a decreased immune function and an associated reduction in antioxidant defence is expected after autotomy. In line with this, after lamellae autotomy, larvae of the damselfly Lestes viridis showed lower levels of innate immunity (i.e. phenoloxidase, PO) and antioxidant defence (superoxide dismutase, SOD). Levels of catalase (CAT) remained, however, unaffected. In line with its cytotoxicity, PO covaried positively w
APA, Harvard, Vancouver, ISO, and other styles
22

Yang, Li, Yu-Xi Feng, and Xiao-Zhang Yu. "Comparative response of SOD at molecular level in different plants against cadmium and drought stress." Applied Environmental Biotechnology 5, no. 1 (2020): 15–28. http://dx.doi.org/10.26789/aeb.2020.01.003.

Full text
Abstract:
Abiotic stress like drought and heavy metal imposes a negative impact on exposed plants’ growth and development, commences over production of reactive oxygen species (ROS) inside plant cells resulting in oxidative stress at the cellular level. After that, plants activate multiple defense mechanisms, within which the superoxide dismutase (SOD) family acts as the first line of defense to eliminate ROS. From the literature, it is evident that fewer studies have been carried out in combination with molecular evolution and phylogenetics, and expression profile of the SOD genes amidst dicot and the
APA, Harvard, Vancouver, ISO, and other styles
23

Khan, Wasi Ullah, Latif Ullah Khan, Dan Chen, and Fei Chen. "Comparative Analyses of Superoxide Dismutase (SOD) Gene Family and Expression Profiling under Multiple Abiotic Stresses in Water Lilies." Horticulturae 9, no. 7 (2023): 781. http://dx.doi.org/10.3390/horticulturae9070781.

Full text
Abstract:
Plants in their natural habitat frequently face different biotic and abiotic stresses, which lead to the production of reactive oxygen species (ROS) that can damage cell membranes, cause peroxidation and deterioration of macromolecules, and ultimately result in cell death. Superoxide dismutase (SOD), a class of metalloenzymes, is primarily found in living organisms and serves as the principal line of defense against ROS. The SOD gene family has not yet been characterized in any species of water lily from the genus Nymphaea. The present study aims to conduct a genome-wide study to discover SOD
APA, Harvard, Vancouver, ISO, and other styles
24

Nayan, Nazatul Shima, Muhammad Aiman Mohd Yazid, Kamachisree Nallappan, et al. "In Vitro Modulation of Endogenous Antioxidant Enzyme Activities and Oxidative Stress in Autism Lymphoblastoid Cell Line (ALCL) by Stingless Bee Honey Treatment." Oxidative Medicine and Cellular Longevity 2020 (December 1, 2020): 1–7. http://dx.doi.org/10.1155/2020/4539891.

Full text
Abstract:
Autism has been associated with a low antioxidant defense mechanism, while honey has been known for decades for its antioxidant and healing properties. Determination of stingless bee honey (KH) effects on antioxidant enzyme activities and oxidative damage in Autism Lymphoblastoid Cell Line (ALCL) was performed. ALCL and its normal sibling pair (NALCL) were cultured in RPMI-1640 medium at 37°C and 5% CO2. ALCL was treated with 400 μg/mL KH (24 h), and oxidative stress marker, malondialdehyde (MDA), and antioxidant enzyme activities (catalase (CAT), glutathione peroxidase (GPx), and superoxide d
APA, Harvard, Vancouver, ISO, and other styles
25

Lin, Tianyi, Ren Zhou, Yange Wu, Minxia Gu, Bo Bi, and Mingliang Chai. "The relationship between morphology changes and antioxidant enzymes activity during somatic embryogenesis of long-term-maintained callus of Zoysia matrella (L.) Merr." Canadian Journal of Plant Science 101, no. 4 (2021): 500–507. http://dx.doi.org/10.1139/cjps-2020-0078.

Full text
Abstract:
A callus line of manila grass [Zoysia matrella (L.) Merr.] has been maintained for 8 years in our laboratory. The present study investigated changes in ultrastructure and antioxidant enzyme activity during regeneration of the callus and examined the correlation between these changes and regeneration ability. The changes in fresh weight and diameter of the callus over time could be described by a sigmoidal growth curve with different stages. Electron microscopy revealed small embryonic callus cells, isodiametric in shape, with large, obvious nuclei, and dense cytoplasm. The cellular structures
APA, Harvard, Vancouver, ISO, and other styles
26

Mohseni, Roohollah, Zahra Arab Sadeghabadi, Mohammad Taghi Goodarzi, Maryam Teimouri, Mitra Nourbakhsh, and Maryam Razzaghy Azar. "Evaluation of Mn-superoxide dismutase and catalase gene expression in childhood obesity: its association with insulin resistance." Journal of Pediatric Endocrinology and Metabolism 31, no. 7 (2018): 727–32. http://dx.doi.org/10.1515/jpem-2017-0322.

Full text
Abstract:
Abstract Background Obesity is associated with oxidative stress. Superoxide dismutase (SOD) is the first line of defense against reactive oxygen species (ROS), eliminating the strong superoxide radical and producing H2O2, which can then be degraded by catalase (CAT). The main objective of this study was to evaluate the gene expression antioxidant enzymes (Mn-SOD and CAT) in peripheral blood mononuclear cells (PBMCs) of obese and normal-weight children, and its association with anthropometric and biochemical parameters. Methods Thirty obese and 30 control subjects between the ages of 8 and 16 y
APA, Harvard, Vancouver, ISO, and other styles
27

Frantziyantz, Elena, Farkhad Dzhabarov, Liudmila Rosenko, Victoria Pozdnyakova, and Ekaterina Komarova. "Metabolic state of perifocal zone and resection line of skin melanoma." Journal of Clinical Oncology 30, no. 15_suppl (2012): e19049-e19049. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.e19049.

Full text
Abstract:
e19049 Background: The state of metabolism in perifocal zone and morphologically intact skin along resection line is of importance for the processes of neoplasm metastasizing and relapse, including skin melanoma. Normalization of the state of free-radical processes, first of all along resection line, and then in neoplasm perifocal zone, should be a characteristic of pathogenically substantiated neoadjuvant influence. Methods: to study activity of free-radical processes in tissue of skin melanoma relapse, its perifocal zone (PZ) (1 cm from tumour edge) and in skin along resection line (3-5 cm f
APA, Harvard, Vancouver, ISO, and other styles
28

Lima, Luíza Siqueira, Nayara de Souza da Costa, Maria Eduarda Andrade Galiciolli, et al. "Assessment of Neurotoxic Effects of Oxycodone and Naloxone in SH-SY5Y Cell Line." International Journal of Molecular Sciences 24, no. 2 (2023): 1424. http://dx.doi.org/10.3390/ijms24021424.

Full text
Abstract:
Opioid drugs have analgesic properties used to treat chronic and post-surgical pain due to descending pain modulation. The use of opioids is often associated with adverse effects or clinical issues. This study aimed to evaluate the toxicity of opioids by exposing the neuroblastoma cell line (SH-SY5Y) to 0, 1, 10, and 100 µM oxycodone and naloxone for 24 h. Analyses were carried out to evaluate cell cytotoxicity, identification of cell death, DNA damage, superoxide dismutase (SOD), glutathione S-transferase (GST), and acetylcholinesterase (AChE) activities, in addition to molecular docking. Oxy
APA, Harvard, Vancouver, ISO, and other styles
29

Belyakov, Vladimir, and Alexsandra Kuporova. "On Peat Production Capacity in Verkhoyansky District, Sakha (Yakutia) Republic." E3S Web of Conferences 41 (2018): 01047. http://dx.doi.org/10.1051/e3sconf/20184101047.

Full text
Abstract:
The article analyzes the possible substitution of long-range coal with peat fuel in boilerhouses of Batagai settlement, the Sakha (Yakutia) Republic, and technical and ecological problems that arise. Potential in-situ resources for permafrost production of moulded solid fuel with peat are examined. The study introduces two options of peat fuel production for boilerhouses: peat milling and sod peat moulding. Experimental work on sod peat drying shows that sod peat can be cut and dried to the conditioned moisture content in northern Yakutia but it is inexpedient both technologically and ecologic
APA, Harvard, Vancouver, ISO, and other styles
30

Gautam, Anuradha, Fatima Nazish Khan, Surabhi Priya, et al. "Cloning and comparative modeling identifies a highly stress tolerant Cu/Zn cytosolic super oxide dismutase 2 from a drought tolerant maize inbred line." PeerJ 11 (March 13, 2023): e14845. http://dx.doi.org/10.7717/peerj.14845.

Full text
Abstract:
Plants have a complex system of stress response that deals with different types of stresses. Maize (Zea mays L.), one of the most important crops grown throughout the world, across a range of agro-ecological environments, employs complex mechanisms of gene regulation in response to drought stress. HKI 335 is a tropical maize inbred line showing remarkable adaptation to drought stress. Abiotic stresses, like drought, trigger the production of reactive oxygen species (ROS) due to the incomplete reduction or excitation of molecular oxygen, eventually leading to cell damage. Superoxide dismutase (
APA, Harvard, Vancouver, ISO, and other styles
31

Rubio, Maria C., Javier Ramos, K. Judith Webb, et al. "Expression Studies of Superoxide Dismutases in Nodules and Leaves of Transgenic Alfalfa Reveal Abundance of Iron-Containing Isozymes, Posttranslational Regulation, and Compensation of Isozyme Activities." Molecular Plant-Microbe Interactions® 14, no. 10 (2001): 1178–88. http://dx.doi.org/10.1094/mpmi.2001.14.10.1178.

Full text
Abstract:
The composition of antioxidant enzymes, especially superoxide dismutase (SOD), was studied in one nontransgenic and three transgenic lines of nodulated alfalfa plants. Transgenic lines overproduced MnSOD in the mitochondria of nodules and leaves (line 1–10), MnSOD in the chloroplasts (line 4–6), and FeSOD in the chloroplasts (line 10–7). In nodules of line 10–7, the absence of transgene-encoded FeSOD activity was due to a lack of mRNA, whereas in nodules of line 4-6 the absence of transgene-encoded MnSOD activity was due to enzyme inactivation or degradation. Transgenic alfalfa showed a novel
APA, Harvard, Vancouver, ISO, and other styles
32

Li, Cong, Lie-Bao Han, and Xunzhong Zhang. "Enhanced Drought Tolerance of Tobacco Overexpressing OjERF Gene Is Associated with Alteration in Proline and Antioxidant Metabolism." Journal of the American Society for Horticultural Science 137, no. 2 (2012): 107–13. http://dx.doi.org/10.21273/jashs.137.2.107.

Full text
Abstract:
Drought stress is one of the major limiting factors for plant growth and development. The mechanism of drought tolerance has not been well understood. This study was designed to investigate proline and antioxidant metabolism associated with drought tolerance in transgenic tobacco (Nicotiana tabacum) plants overexpressing the OjERF gene relative to wild-type (WT) plants. The OjERF gene was isolated from mondo grass (Ophiopogon japonicus). The OjERF gene, driven by the CaMV35S promoter, was introduced into tobacco through agrobacterium (Agrobacterium tumefaciens)-mediated transformation. Five tr
APA, Harvard, Vancouver, ISO, and other styles
33

Romero, P., M. D. Coello, C. A. Aragón, and A. L. Eusebi. "Sludge reduction at low ozone doses: predictive effects and full-scale study." Water Science and Technology 71, no. 2 (2014): 191–96. http://dx.doi.org/10.2166/wst.2014.486.

Full text
Abstract:
The activated sludge process is the most widely used wastewater treatment. The main drawback of this technology is the excess sludge production (ESP). The ozonation of sludge of the recirculation line is used to reduce the ESP. In this study, ozonation was applied on a fraction of sludge of the recirculation line in a full-scale plant (50,000 population equivalent) at a lower–specific ozone dose (SOD) compared to previous studies. The results of batch tests to predict the main effect of the technology on the biomass activities are reported. Specifically, tests at 0.7–5 g O3/kg MLVSS (mixed liq
APA, Harvard, Vancouver, ISO, and other styles
34

Suvarna, Reshma, Prasanna K. Rao, Preethi A. Poonja, Devishree Rai, Raghavendra Kini, and HC Meghana. "Salivary superoxide dismutase activity in smokeless tobacco consumers and non-consumers: A biochemical study." Journal of Cancer Research and Therapeutics 19, no. 5 (2023): 1359–64. http://dx.doi.org/10.4103/jcrt.jcrt_1057_21.

Full text
Abstract:
ABSTRACT Aim and Objective: Tobacco can alter the antioxidative capacity of saliva, and it is the first fluid that is exposed to tobacco. Superoxide dismutase (SOD) is the first line defense antioxidant that plays an important protective role against peroxidation of lipids, converts superoxide radicals into hydrogen peroxide, and decreases the toxic effects of free radicals. The aim of this study was to estimate and compare the levels and activity of SOD in the saliva of smokeless tobacco (SLT) consumers and non-consumers. Method and Methodology: Total of 64 individuals were divided into two g
APA, Harvard, Vancouver, ISO, and other styles
35

Lu, Hua, Junhui Zhen, Tianfu Wu, et al. "Superoxide dismutase mimetic drug tempol aggravates anti-GBM antibody-induced glomerulonephritis in mice." American Journal of Physiology-Renal Physiology 299, no. 2 (2010): F445—F452. http://dx.doi.org/10.1152/ajprenal.00583.2009.

Full text
Abstract:
Oxidative stress plays an important role in the pathogenesis of anti-glomerular basement membrane antibody-induced glomerulonephritis (anti-GBM-GN). Superoxide dismutase (SOD) is the first line of defense against oxidative stress by converting superoxide to hydrogen peroxide (H2O2). We investigated the effect of the SOD mimetic drug tempol on anti-GBM-GN in mice. 129/svJ mice were challenged with rabbit anti-mouse-GBM sera to induce GN and subsequently divided into tempol (200 mg·kg−1·day−1, orally) and vehicle-treated groups. Routine histology, SOD and catalase activities, malondialdehyde (MD
APA, Harvard, Vancouver, ISO, and other styles
36

Salvi, Ankita, Gaurav Patki, Eisha Khan, Mohammad Asghar, and Samina Salim. "Protective Effect of Tempol on Buthionine Sulfoximine-Induced Mitochondrial Impairment in Hippocampal Derived HT22 Cells." Oxidative Medicine and Cellular Longevity 2016 (2016): 1–8. http://dx.doi.org/10.1155/2016/5059043.

Full text
Abstract:
Using a simulated oxidative stress model of hippocampus-derived immortalized cell line (HT22), we report that prooxidant buthionine sulfoximine (BSO, 1 mM, 14 h), without adversely affecting cell viability or morphology, induced oxidative stress by inhibiting glutathione synthesis. BSO treatment also significantly reduced superoxide dismutase (SOD) activity (p<0.05) and significantly lowered total antioxidant capacity (p<0.001) in HT22 cells when compared to vehicle treated control cells. Antioxidant tempol, a piperidine nitroxide considered a SOD mimetic, reversed BSO-induced decline in
APA, Harvard, Vancouver, ISO, and other styles
37

Sakudo, Akikazu, Deug-chan Lee, Shuming Li, et al. "PrP cooperates with STI1 to regulate SOD activity in PrP-deficient neuronal cell line." Biochemical and Biophysical Research Communications 328, no. 1 (2005): 14–19. http://dx.doi.org/10.1016/j.bbrc.2004.12.132.

Full text
APA, Harvard, Vancouver, ISO, and other styles
38

Vilela, Danielle Rezende, Édila Vilela de Resende Von Pinho, Wilson Vicente Souza Pereira, et al. "The expression of the ZmDREB2A/2.1S and ZmPP2C genes is a potential marker for the detection of drought-tolerant maize at high planting densities." Australian Journal of Crop Science 18, no. 10 (2024): 666–72. https://doi.org/10.21475/ajcs.24.18.10.p73.

Full text
Abstract:
The efficacy of a breeding program hinges on its ability to swiftly select desirable lines, as the expression of some key genes is a rapid and efficient marker. Although a wide range of genes are involved in water deficit tolerance, their expression is of considerable interest in maize breeding programs. Thus, this research aimed to analyse the expression of several water deficit-related genes in two contrasting maize lines. Two contrasting lines for drought tolerance (L91-T – tolerant and L24-NT – nontolerant) were sown and grown at two densities—60 and 120 thousand plants/hectare. Leaves, st
APA, Harvard, Vancouver, ISO, and other styles
39

Djawad, Khairuddin. "The effectiveness of Oral Superoxide Dismutase (SOD) on total antioxidant status, Trans Epidermal Water Loss (TEWL) and sebum concentration in photo aging skin." Research, Society and Development 10, no. 1 (2021): e32410111402. http://dx.doi.org/10.33448/rsd-v10i1.11402.

Full text
Abstract:
Introduction: Aging is a progressive process of decrease in organs functions and capacity, including the skin. Photoaging is extrinsic aging mainly occur due to ultraviolet (UV) exposure. Methods: This study is a clinical trial research design with one group pre-post test. All subjects who were exposed to UV for approximately 3-4 hours. All subjects signed an informed consent and were interviewed accordingly. Photoaging was diagnosed clinically by three dermatologists according to Glogau type II classification such as dynamic wrinkles, palpable keratosis, visible lentigo senilis, and smiley li
APA, Harvard, Vancouver, ISO, and other styles
40

AI, HUI, PEIPEI ZHU, WENHUI XIONG, BIN XIA, and ZHIWEN ZOU. "Regulation of three subtypes of SOD gene in Aleuroglyphus ovatus (Acari: Acaridae) under lead stress." Zoosymposia 22 (November 30, 2022): 257. http://dx.doi.org/10.11646/zoosymposia.22.1.158.

Full text
Abstract:
Superoxide dismutase (SOD) is an important enzyme that acts as the first line of protection in the mite antioxidant defense system and involves in eliminating reactive oxygen species (ROS) under harsh environmental conditions. Lead pollution is becoming increasingly serious and poses a serious hazard to the health and survival and reproduction of organisms. Nevertheless, the SOD gene family was yet to be reported in stored grain pest mite (Aleuroglyphus ovatus). In the present study, A. ovatus was reared on artificial diets treated with different concentrations of lead (12.5, 25, 50 and 100 mg
APA, Harvard, Vancouver, ISO, and other styles
41

Henry Wicaksono, Mahrus A Rahman, Roedi Irawan, I Ketut Alit Utamayasa, Teddy Ontoseno, and Taufiq Hidayat. "The level of superoxide dismutase and catalase in acyanotic congenital heart disease children with heart failur." GSC Biological and Pharmaceutical Sciences 16, no. 1 (2021): 150–56. http://dx.doi.org/10.30574/gscbps.2021.16.1.0206.

Full text
Abstract:
Background: The most common complication in acyanotic congenital heart disease (CHD) is heart failure which definitive diagnosis and therapy remain unsatisfactory. Heart failure’s progression is often associated with oxidative stress process. Superoxide dismutase (SOD) is the first line antioxidant of defense against superoxide anion. While Catalase (CAT) breaks down hydrogen peroxide into water and oxygen molecules which complements previous detoxification carried out by SOD. Objective: This study aimed to compare the differences of SOD and CAT levels in acyanotic CHD patients between those w
APA, Harvard, Vancouver, ISO, and other styles
42

Bowden, Christine G., Daniel J. Royse, and Bernie May. "Linkage relationships of allozyme-encoding loci in shiitake, Lentinula edodes." Genome 34, no. 4 (1991): 652–57. http://dx.doi.org/10.1139/g91-099.

Full text
Abstract:
Single spore derived isolates from two parental and seven hybrid lines of Lentinula edodes were analyzed for single locus and joint segregation of 21 allozyme-encoding loci. The two alleles at the individual loci departed significantly from a 1:1 Mendelian ratio in 11% of the tests. With the exception of the highly significant χ2 value for Aat-1 in line WC131 (χ2 = 41.78), aberrant ratios were marginally significant and probably were due to chance alone. Eight linkages were identified: Ada ~ Gda, recombination frequency (r) = 0.15; Ada ~ Est, r = 0.12; Est ~ Gpi, r = 0.29; Ada ~ Gpi, r = 0.35;
APA, Harvard, Vancouver, ISO, and other styles
43

Abreu, Viviane Maria de, Édila Vilela de Resende Von Pinho, Renzo Garcia Von Pinho, et al. "Physiological performance and expression of isozymes in maize seeds subjected to water stress." Journal of Seed Science 36, no. 1 (2014): 40–47. http://dx.doi.org/10.1590/s2317-15372014000100005.

Full text
Abstract:
Early characterization of genotypes, through the previous assessment of physiological quality of their seeds and their enzymatic systems, can provide parameters capable of aiding in the selection of new maize cultivars tolerant to water stress. Thus, this study was aimed at assessing seed performance of five different maize lines subjected to four different water stress levels. The physiological quality of seeds germinated under the osmotic potentials of 0.0, -0.3, -0.6 and -0.9 MPa was assessed by germination test, number of strong normal seedlings and T50, as well as by the expression of the
APA, Harvard, Vancouver, ISO, and other styles
44

Zang, Yu, Jun Chen, Ruoxi Li, Shuai Shang, and Xuexi Tang. "Genome-wide analysis of the superoxide dismutase (SOD) gene family in Zostera marina and expression profile analysis under temperature stress." PeerJ 8 (May 5, 2020): e9063. http://dx.doi.org/10.7717/peerj.9063.

Full text
Abstract:
Superoxide dismutases (SODs) serve as the first line of defense in the plant antioxidant enzyme system, and play a primary role in the removal of reactive oxygen species (ROS). However, our understanding of the functions of the SOD family in Zostera marina is limited. In this study, a systematic analysis was conducted on the characteristics of the SOD genes in Z. marina at the whole-genome level. Five SOD genes were identified, consisting of two Cu/ZnSODs, two FeSODs, and one MnSOD. Phylogenetic analysis showed that ZmSOD proteins could be divided into two major categories (Cu/ZnSODs and Fe-Mn
APA, Harvard, Vancouver, ISO, and other styles
45

Moreno-Lafont, Martha Cecilia, Raul Flores-Mejia, Octavio Rodriguez-Cortes, Rommel Chacon-Salinas, and Mario Cancino-Diaz. "Specific T lymphocyte citotoxicity induced by Cu/Zn superoxide dismutase from Brucella abortus RB51 (B124)." Journal of Immunology 178, no. 1_Supplement (2007): LB26. http://dx.doi.org/10.4049/jimmunol.178.supp.b124.

Full text
Abstract:
Abstract Brucellosis is an infectious disease affecting animals and humans, caused mainly by B. abortus. Although several vaccines have been developed, B. abortus strain RB51 is the most used for cattle, but is not useful for humans since it causes severe granulomas. To develop a vaccine for humans, Cu-Zn superoxide dismutase (SOD Cu/Zn) has been identified as an antigen which induces T-cell mediated immunity in mice vaccinated with live Escherichia coli expressing B. abortus SOD Cu/Zn or a plasmid DNA carrying the gene sodC. The aim of this work was to demonstrate the induction by SOD Cu/Zn f
APA, Harvard, Vancouver, ISO, and other styles
46

Mercy Nnam, Ngozi, Eucharia Chinyere Agbo, and Peace Nwanneka Ani. "Effects of Christmas Bush (Chromolaena Odorata), Cathedral Bells (Bryophyllum Pinnatum) and Water Leaf (Talinium Triangulare) Leaf Extracts on Biochemical Markers, and Ulcer Parameters of Ulcer-Induced Adult Male Wistar Rats." Journal of Genetic Engineering and Biotechnology Research 7, no. 1 (2025): 01–09. https://doi.org/10.33140/jgebr.07.01.03.

Full text
Abstract:
Many medicinal plants are commonly used in traditional treatment of ulcer however, the dosages remain unclear. The study examined the effects of Chromolaena odorata, Bryophyllum pinnatum and Talinium triangulare leaf extracts on biochemical markers and ulcer parameters of ulcer-induced adult male wistar rats. Christmas bush and cathedral bells leaves were harvested from Nsukka town, while water leaf was bought from Ogige market at Nsukka, Enugu State. They leaves were processed into flour and marcerated in water for 48 hours to obtain extracts. Adult male Wistar rats (72) were acclimatized and
APA, Harvard, Vancouver, ISO, and other styles
47

Portes, Alejandro. "The Sociology of Development." Sociology of Development 1, no. 1 (2015): 20–42. http://dx.doi.org/10.1525/sod.2015.1.1.20.

Full text
Abstract:
This paper summarizes the main theories conventionally associated with the sociology of development as well as the arguments of the principal scholars focused on what “works” to bring about economic development and social progress. This line of argument ushered the rising consensus across the social sciences that the prime causal role belongs to institutions. However, the empirical literature that has followed from this consensus has been marred by a lack of proper definition of the concept and a tendency to use nations as units of analysis, neglecting their internal complexity. The last secti
APA, Harvard, Vancouver, ISO, and other styles
48

Djawad, Khairuddin, and Dewi Anggraini. "THE EFFECTIVENESS OF ORAL SUPEROXIDE DISMUTASE (SOD) ON TOTAL ANTIOXIDANT STATUS, TRANSEPIDERMAL WATER LOSS (TEWL) AND SEBUM CONCENTRATION IN PHOTO AGING SKIN." Medical Science of Ukraine (MSU) 17, no. 1 (2021): 47–56. http://dx.doi.org/10.32345/2664-4738.1.2021.06.

Full text
Abstract:
Relevance. Aging is a progressive process of decrease in organs functions and capacity, including the skin. Photoaging is extrinsic aging mainly occurs due to ultraviolet (UV) exposure. The effectiveness of oral SOD for premature aging is still not yet known.
 Objective: We aimed to evaluate the effectiveness of this antioxidant on total antioxidant status (TAS), skin hydration (TEWL), and sebum concentration in premature skin aging.
 Methods. This study is a clinical trial research design with one group pre-post test. All subjects were exposed to UV for approximately 3-4 hours. All
APA, Harvard, Vancouver, ISO, and other styles
49

Goroshinskaya, I. A., E. M. Frantsiyants, I. V. Kaplieva, et al. "Free radical processes in rat liver in experimental diabetes, malignant growth and their combination." Research and Practical Medicine Journal 9, no. 2 (2022): 21–33. http://dx.doi.org/10.17709/2410-1893-2022-9-2-2.

Full text
Abstract:
Purpose of the study. To study the intensity of lipid peroxidation (LPO) and indicators of antioxidant protection in the liver of rats of different sexes with combined pathology – the growth of Guerin's carcinoma in presence of experimental type 1 diabetes mellitus.Materials and methods. The levels of malondialdehyde (MDA) and diene conjugates (DC), the activities of superoxide dismutase (SOD) and catalase, and the levels of vitamins A and D were studied by conventional spectrophotometric methods in liver tissue samples from males and females with alloxan‑induced diabetes mellitus (DM), transp
APA, Harvard, Vancouver, ISO, and other styles
50

Henriques, Alexandre, Claudia Pitzer, and Armin Schneider. "Characterization of a Novel SOD-1(G93A) Transgenic Mouse Line with Very Decelerated Disease Development." PLoS ONE 5, no. 11 (2010): e15445. http://dx.doi.org/10.1371/journal.pone.0015445.

Full text
APA, Harvard, Vancouver, ISO, and other styles
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!