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Journal articles on the topic 'Sodium Alginate Beads'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Sharma, Diksha, Samriti Samriti, Mukul Sharma, Deepak Prashar, Namrata Namrata, and Heena Sharma. "Formulation and Assessment of Floating Sodium Alginate Beads of Analgesic Drug." International Journal of Pharmaceutical Research and Applications 09, no. 06 (2024): 1411–15. https://doi.org/10.35629/4494-090614111415.

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The main aim of this present research is to develop gastro retentive sustain release alginate beads of diclofenac sodium by ionotropic gelation method. Preparation of floating bead of diclofenac sodium was made by the dispersion of diclofenac sodium together with CaCl2 into solution of sodium alginate. In this study an attempt was done to prepare a controlled release sodium alginate beads comprised of diclofenac sodium drug. Produced beads were evaluated for encapsulation efficiency, swelling index, in- vitro dissolution studies etc.

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2

Oppelt, Marie, and Christos G. Aneziris. "Analysis and Evaluation of Different Influencing Factors in Processing of Hollow and Full Beads by Alginate Gelation Based on Zirconia and TRIP Steel." Materials Science Forum 825-826 (July 2015): 158–66. http://dx.doi.org/10.4028/www.scientific.net/msf.825-826.158.

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A novel and innovative process for full as well as hollow metal-matrix composite bead fabrication using gel-casting process by alginate gelation is investigated. In particular the influence of four different alginates and various solidifying agents have been investigated regarding the formation and stability of full and hollow beads. The suspension contained a metastable austenitic steel powder (16Cr7Mn3Ni) and zirconia particles as well as different alginates and was added dropwise into water containing different solidifying agents for forming beads. With the aid of sodium and potassium algin

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3

Yi-cheng, Wu, Yang Ai-li, Gao Wei, Fu Hai-yan, and Wang Ze-jie. "Al2O3 Nanoparticles Promote the Removal of Carbamazepine in Water by Chlorella vulgaris Immobilized in Sodium Alginate Gel Beads." Journal of Chemistry 2020 (May 26, 2020): 1–6. http://dx.doi.org/10.1155/2020/8758432.

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The roles of Al2O3 nanoparticles on the removal of carbamazepine (CBZ) by Chlorella vulgaris immobilized in sodium alginate gel beads were for the first time investigated. The optimum conditions to prepare immobilized C. vulgaris beads with addition of Al2O3 nanoparticles were determined as follows: C. vulgaris density was 3.0 × 106 cells for 1 mL sodium alginate solution, Al2O3 nanoparticle concentration was 0.5 g/L, and concentrations of sodium alginate and CaCl2 were 1.6% and 1%, respectively. The results showed that the proposed algae beads achieved the highest CBZ removal rate of 89.6% af

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4

Mohd, Yasir, A. Bhattacharyya, M. Bajpai, M. Yasir, and M. Asif. "Formulation and In vitro Characterization of Floating Gel Beads of Metformin Hydrochloride." International Journal of Pharmaceutical Sciences and Nanotechnology 7, no. 1 (2014): 2356–62. http://dx.doi.org/10.37285/ijpsn.2014.7.1.7.

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A floating type dosage form, gel beads of metformin hydrochloride was prepared by emulsification gelation technique. The gel bead was formed by mixing the polymer in water, oil phase and it was extruded in the calcium chloride solution as curing agent. The formulation parameters optimized were polymer ratio, concentration of oil, curing time on drug content, floating lag time, morphology, swelling of beads and release kinetics.The scanning electron photomicrographs revealed morphology of beads. The size of beads was measured. Entrapment efficiency of drug loaded beads was found to be over 90%.

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5

Jung, Yu-Kyung, Alam Venugopal Narendra Kumar, Byong-Hun Jeon, Eun Young Kim, Taewoo Yum, and Ki-Jung Paeng. "Exploration of Zero-Valent Iron Stabilized Calcium–Silicate–Alginate Beads’ Catalytic Activity and Stability for Perchlorate Degradation." Materials 15, no. 9 (2022): 3340. http://dx.doi.org/10.3390/ma15093340.

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Perchlorate contamination in groundwater poses a serious threat to human health, owing to its interference with thyroid function. The high solubility and poor adsorption of perchlorate ions make perchlorate degradation a necessary technology in groundwater contaminant removal. Here, we demonstrate the perchlorate degradation by employing nano zero-valent iron (nZVI) embedded in biocompatible silica alginate hybrid beads fabricated using calcium chloride (1 wt%) as a crosslinker. The concentration of precursors (sodium alginate, sodium silicate) for bead formation was standardized by evaluating

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6

Taweetanawanit, Pongsatorn, Thana Radpukdee, Nguyen Thanh Giao, and Sumana Siripattanakul-Ratpukdi. "Mechanical and Chemical Stabilities of Barium Alginate Gel: Influence of Chemical Concentrations." Key Engineering Materials 718 (November 2016): 62–66. http://dx.doi.org/10.4028/www.scientific.net/kem.718.62.

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There has been increasing interest of alginate gel utilization for environmental application. This study was aimed to investigate influence of sodium alginate and barium chloride concentrations on mechanical and chemical stabilities of the barium alginate gel. The barium alginate beads were mechanically tested using universal testing machine while the beads were soaked in the solutions with pHs of 5 to 9 or salts (sodium chloride, potassium chloride, and sodium hydrogen carbonate) for chemical stability test. The result showed that concentrations of barium chloride and sodium alginate obviousl

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7

Kalogeropoulou, Flora, Dimitra Papailiou, Chrystalla Protopapa, et al. "Design and Development of Low- and Medium-Viscosity Alginate Beads Loaded with Pluronic® F-127 Nanomicelles." Materials 16, no. 13 (2023): 4715. http://dx.doi.org/10.3390/ma16134715.

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The anionic polymer sodium alginate, a linear copolymer of guluronic and mannuronic acids, is primarily present in brown algae. Copolymers are used in the sodium alginate preparation process to confer on the material strength and flexibility. Micelles and other polymeric nanoparticles are frequently made using the triblock copolymer Pluronic® F-127. The purpose of the present study is to determine the effect of sodium alginate’s viscosity (low and medium) and the presence of Pluronic® F-127 micelles on the swelling behavior of the prepared pure beads and those loaded with Pluronic® F-127 micel

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8

Sahithi, Malapati Lakshmi, Venugopalaiah Penabaka, and Yadala Prapurna Chandra. "Formulation and characterization of capecitabine muco adhesive beads for the treatment of colorectal cancer." International Journal of Clinical Pharmacokinetics and Medical Sciences 5, no. 1 (2025): 1–11. https://doi.org/10.26452/ijcpms.v5i1.699.

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This study focuses on the formulation and characterisation of Capecitabine muco-adhesive beads for the treatment of colorectal cancer. The alginate beads were synthesised using the ionotropic external gelation technique. To maximise encapsulation efficiency and control the release of Capecitabine from the alginate beads, precise formulation conditions were implemented. Results from in vitro dissolution studies revealed that formulations incorporating increasing concentrations of sodium alginate with SCMC released the drug more rapidly compared to those formulated with sodium alginate and HPMC.

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9

Soo, Chen-Lin, Cheng-Ann Chen, Othman Bojo, and Yii-Siang Hii. "Feasibility of Marine Microalgae Immobilization in Alginate Bead for Marine Water Treatment: Bead Stability, Cell Growth, and Ammonia Removal." International Journal of Polymer Science 2017 (November 13, 2017): 1–7. http://dx.doi.org/10.1155/2017/6951212.

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Sodium alginate is the most commonly used polymer matrix in microalgae immobilization for water treatment. However, the susceptibility of alginate matrixes to cation chelating agents and antigelling cation limits the use of alginates in estuarine and marine systems. Hence, the present study aims to investigate the stability of alginate bead in marine water and the feasibility of microalgae to grow when immobilized in alginate bead for marine water treatment. Different concentrations of alginate and hardening cation calcium were used to formulate beads. The beads were incubated in Guillard’s f/

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10

Lateef, Surra, Masar Basim, and Afrah Mohammed. "Effect Of Different Variables On The Formulation Of Sodium Alginate Beads." Al Mustansiriyah Journal of Pharmaceutical Sciences 24, no. 2 (2024): 117–26. http://dx.doi.org/10.32947/ajps.v24i2.1007.

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This work examined the possibility of encapsulating prednisolone as drug modelling in Na-alginate polymeric beads. Our beads were formulated by ionotropic gelation method using Na-alginate as an anionic natural polysaccharide polymer and Cacl2 as a positive charge cross-linker. Eleven formulations were successfully created, and different variations were evaluated, including Na-alginate concentration ( 0.5, 2, 3) w/v %, Cacl2 concentration (1, 3, 5) w/v % stirring speed (100, 300, 400) rpm, the addition of tween-80 (0, 2.5, 5) ml, washing beads with alcohol, change curing time. The beads were a

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11

Lee, Ki-Yong, and Tae-Ryeon Heo. "Survival of Bifidobacterium longumImmobilized in Calcium Alginate Beads in Simulated Gastric Juices and Bile Salt Solution." Applied and Environmental Microbiology 66, no. 2 (2000): 869–73. http://dx.doi.org/10.1128/aem.66.2.869-873.2000.

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ABSTRACT Bifidobacterium longum KCTC 3128 and HLC 3742 were independently immobilized (entrapped) in calcium alginate beads containing 2, 3, and 4% sodium alginate. When the bifidobacteria entrapped in calcium alginate beads were exposed to simulated gastric juices and a bile salt solution, the death rate of the cells in the beads decreased proportionally with an increase in both the alginate gel concentration and bead size. The initial cell numbers in the beads affected the numbers of survivors after exposure to these solutions; however, the death rates of the viable cells were not affected.

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12

Yoga Saputra, I. Made, Nyoman Semadi Antara, and Ida Bagus Wayan Gunam. "PENGARUH KONSENTRASI Na-ALGINAT DAN UKURAN BEADS TERHADAP STABILITAS BEADS DAN AKTIVITAS SEL Agrobacterium tumefaciens LSU20 IMMOBIL DALAM BIODESULFURISASI DIBENZOTHIOFENA." JURNAL REKAYASA DAN MANAJEMEN AGROINDUSTRI 6, no. 2 (2018): 169. http://dx.doi.org/10.24843/jrma.2018.v06.i02.p08.

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The purpose of this study was to determine the concentration and size of Na-alginate beads that have the highest degradation activity of dibenzothiophene. Biodesulfurization (BDS) of dibenzothiophene (DBT) was performed using 3 Na-alginate concentrations and 3 different beads sizes in the oil model system. Biodesulfurization was performed with incubation for 24 hours. The previous research showed that sodium alginate (Na-alginate) was an appropriate immobilizing agent compared to other immobilized materials. Na-alginate 4% show the activity of the degradation of the most good that is 66.33% (b

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13

Yadav, Manish, B. Srivastava, Vijay Bhalla, Naresh Kalra, and Kavita Attri. "Preparation and Evaluation of Ketoprofen-loaded Sodium Alginate Beads." Asian Pacific Journal of Health Sciences 6, no. 1 (2019): 199–205. http://dx.doi.org/10.21276/apjhs.2019.6.1.27.

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14

Storti, Enrico, Marc Neumann, Tilo Zienert, Jana Hubálková, and Christos Georgios Aneziris. "Metal-Ceramic Beads Based on Niobium and Alumina Produced by Alginate Gelation." Materials 14, no. 19 (2021): 5483. http://dx.doi.org/10.3390/ma14195483.

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Full metal-ceramic composite beads containing different amounts of niobium and alumina, particularly 100 vol% alumina, 100 vol% niobium, and 95/5 vol% niobium/alumina, were produced by the alginate gelation process. The suspension for bead fabrication contained sodium alginate as gelling agent and was added dropwise into a calcium chloride solution to trigger the consolidation process. After debinding in air, sintering of the composite beads was performed under inert atmosphere. Samples in green and sintered state were analyzed by digital light microscopy and scanning electron microscopy equip

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15

Te Chuan, Lee, Norpadzlihatun Manap, Hasan Zuhudi Abdullah, and Maizlinda Izwana Idris. "Polyvinyl Alcohol-Alginate Adsorbent Beads for Chromium (VI) Removal." International Journal of Engineering & Technology 7, no. 3.20 (2018): 95. http://dx.doi.org/10.14419/ijet.v7i3.20.18988.

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Chromium pollution has been an increasing concern worldwide because of its high toxicity and carcinogenic properties, and it requires an efficient purification technique. In this study, adsorbent beads containing polyvinyl alcohol (PVA) and sodium alginate were prepared by crosslinking with boric acid and calcium chloride for adsorbent of the hexavalent chromium [Cr (VI)]. Batch adsorption studies were conducted to evaluate Cr (VI) adsorption rates of PVA-alginate beads from aqueous solution under ultraviolet (UV) light illumination. The surface morphology and elemental composition of beads we

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16

Dehghannoudeh, Gholamreza, Kioomars Kiani, Mohammad Hassan Moshafi, et al. "Optimizing the immobilization of biosurfactant-producing Pseudomonas aeruginosa in alginate beads." Journal of Pharmacy & Pharmacognosy Research 7, no. 1 (2019): 413–20. http://dx.doi.org/10.56499/jppres19.628_7.6.413.

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Context: Biosurfactants are amphipathic molecules that reduce surface tension. The major reasons to economically production of the biosurfactant are their health, safety, environmental management, and promising applications. Aims: To optimize the immobilization of Pseudomonas aeruginosa as a biosurfactant producer in alginate beads. Methods: Biosurfactant production by P. aeruginosa was confirmed through the hemolysis test, emulsification index, and surface activity measurement. Calcium alginate encapsulation technique was used in order to entrap the P. aeruginosa cells. Full factorial design

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17

Mormile, Cristina, Ocsana Opriș, Stefano Bellucci, et al. "Natrium Alginate and Graphene Nanoplatelets-Based Efficient Material for Resveratrol Delivery." Gels 11, no. 1 (2024): 15. https://doi.org/10.3390/gels11010015.

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In this study, alginate-based composite beads were developed for the delivery of resveratrol, a compound with therapeutic potential. Two formulations were prepared: one with sodium alginate and resveratrol (AR) and another incorporating graphene nanoplatelets (AGR) to improve drug release control. The beads were formed by exploiting alginate’s ability to gel via ionic cross-linking. For the AGR formulation, sodium alginate was dissolved in water, and graphene was dispersed in isopropyl alcohol to achieve smaller flakes. Resveratrol was dissolved in an ethanol/water mixture and added to the gra

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18

Tonde, A. B., A. A. Bhoite, and N. N. Gaikwad. "Studies on microencapsulation of Lactobacillus acidophilus NCIM 5306 and evaluation of matrix material efficiency in pomegranate juice." Food Research 6, no. 2 (2022): 255–64. http://dx.doi.org/10.26656/fr.2017.6(2).147.

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The present study was conducted on the microencapsulation of Lactobacillus acidophilus NCIM 5306 probiotic lactic acid bacteria. Sodium alginate, sodium alginate + 0.4% chitosan, sodium alginate with 2% inulin, and sodium alginate with 2% inulin + 0.4% chitosan coating were used as microencapsulated matrix material. The extrusion method was used for the formation of various micro encapsulates. The probiotic pomegranate juice was formulated using the obtained beads. The freshly prepared beads were first subjected to viability assay and then inoculated in pasteurized pomegranate juice at 1% quan

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19

I. Hamodi, Mohammad, and Mohammed K. Younis. "PREPARATION, CHARACTERIZATION AND RELEASING -SWELLING KINETICS OF MYRRH BASED HYDROGEL." Science Journal of University of Zakho 11, no. 2 (2023): 139–52. http://dx.doi.org/10.25271/sjuoz.2023.11.2.1147.

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In this work, Myrrh gum was used with sodium alginate (SA) to create novel Myrrh-Alginate beads composite. These beads were produced utilizing the ionotropic gelation technique. Methylene blue (MB) was employed as a drug model to evaluate the kinetics of drug release and the capacity of the synthesized beads to function as a drug delivery system. The molecular interaction between sodium alginate and myrrh was confirmed by FTIR spectroscopy. The physical characteristics of the Myrrh-Alginate beads, including drug content, particle size, thermal properties, equilibrium water content (EWC), swell

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20

Mallikarjuna, B., O. Sreekanth Reddy, K. Pallavi, M. C. S. Subha, and N. Madhavi. "Synthesis, Characterization and Drug delivery of Verapamil Hydrochloride loaded Montmorillonite Nanocomposite Beads." Journal of Drug Delivery and Therapeutics 9, no. 3-s (2019): 443–50. http://dx.doi.org/10.22270/jddt.v9i3-s.2876.

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In the present research programme, Verapamil Hydrochloride loaded Sodium Alginate/Polyethylene oxide/Montmorillonite nanocomposite beads were prepared by using gelation method. Sodium alginate (SA) and Poly ethylene oxide (PEO) with different ratios were blended with different weight ratios of MMT solution. The nanocomposite beads were characterized Fourier Transform Infrared Spectroscopy (FTIR), Scanning Electron Microscope (SEM), X-ray diffraction (X-RD). FTIR was used to understand the hydrogen bonding between SA, PEO, MMT and drug. The X-RD studies were performed to understand the crystall

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21

Peh, Yee-Ming, Boon-Beng Lee, Farizul Hafiz Kasim, Akmal Hadi Ma’Radzi, Ahmad Radi Wan Yaakub, and Hafizah Mohd Johar. "Comparative study on mechanisms of gases release from Ca-alginate beads." BIO Web of Conferences 90 (2024): 01005. http://dx.doi.org/10.1051/bioconf/20249001005.

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Calcium alginate (Ca-alginate) beads have attracted considerable attention as carriers for the controlled release of volatile compounds due to their biocompatibility and tunable properties. This study aimed to compare the release of ethylene and carbon dioxide gas from Ca-alginate beads. Ca-alginate beads were prepared from a sodium alginate solution containing ethephon and calcium carbonate as the gas-forming agent. The resulting solution was then extruded into a calcium chloride solution. The gas release behavior was studied by monitoring the concentration of released gases over time using g

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22

Sangjan, Suntree, and Wadchara Thongsamer. "Facile Fabrication of N-Slow Release Fertilizer Hydrogel Beads by Alginate-Based Composites." Key Engineering Materials 889 (June 16, 2021): 91–97. http://dx.doi.org/10.4028/www.scientific.net/kem.889.91.

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A novel slow-release N-fertilizer hydrogel beads were developed using sodium alginate (SA) and alginate-talcum (ST) composite as N-absorbent. In this work, the hydrogel composite were fabricated by simple method and low cost. N-fertilizer hydrogel beads were prepared two types, for SA types, which were different sodium alginate (1(SA1), 3(SA3), 5(SA5), 7(SA7), and 10(SA10) wt%). And, for ST types, sodium alginate and talcum were vary ratios to 1:0.5(S1T0.5), 1:1(S1T1), and 1:2 (S1T2). The chemical structure of hydrogel composite beads were characterized via Fourier transform infrared spectrosc

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23

Mohd Sukri, Siti Sabrina, and Mimi Sakinah A.M. "Effects of Support Matrix for XylanaseImmobilisationon Alginate Hydrogel Beads." International Journal of Engineering Technology and Sciences 4, no. 1 (2017): 28–35. http://dx.doi.org/10.15282/ijets.7.2017.1.4.1066.

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Enzymes serving as biocatalysts and play an important roles in many industrial field. However, the limitation of enzyme usage due to its high cost and unstable conditions of soluble enzyme to harsh conditions lead to findings an alternative to enhance the enzyme efficiency by immobilisation (insoluble enzyme). The present work reported a combination of immobilisation technique of xylanase by entrapment and covalent binding on alginate hydrogel beads. Xylanase enzyme was effectively immobilised within the support matrix, alginate hydrogel beads by entrapment and covalent binding on the surface

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24

Sadjadi, Samahe, and Abolfazl Heydari. "Palladated Cyclodextrin Nanosponge-Alginate Dual Bead as an Efficient Catalyst for Hydrogenation of Nitroarenes in Aqueous Solution." Polymers 15, no. 15 (2023): 3240. http://dx.doi.org/10.3390/polym15153240.

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In this study, we present a novel composite material consisting of β-cyclodextrin nanosponge and sodium alginate, used as a support for the immobilization of palladium (Pd) nanoparticles. The composite alginate-cyclodextrin nanosponge beads were prepared, taking advantage of the 3D polymeric network and β-cyclodextrin cavity of the nanosponge. These beads exhibited excellent encapsulation capabilities for hydrophobic substrates, allowing their transfer in aqueous media. The cyclodextrin nanosponge served as a stabilizer for Pd nanoparticles and facilitated phase transfer. Additionally, the sod

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25

Xiao, Songtao, Menglin Li, Haifeng Cong, Lingyu Wang, Xiang Li, and Wen Zhang. "Preparation of Highly Porous Thiophene-Containing DUT-68 Beads for Adsorption of CO2 and Iodine Vapor." Polymers 13, no. 23 (2021): 4075. http://dx.doi.org/10.3390/polym13234075.

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Zirconium-based metal-organic frameworks (Zr-MOFs) have great structural stability and offer great promise in the application of gas capture. However, the powder nature of MOF microcrystallines hinders their further industrial-scale applications in fluid-phase separations. Here, Zr-based DUT-68 was structured into nontoxic and eco-friendly alginate beads, and the gas capture properties were evaluated by CO2 and volatile iodine. DUT-68 beads were synthesized via a facile and versatile cross-linked polymerization of sodium alginate with calcium ions. The composite beads keep the structural integ

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26

Baudequin, Timothée, Hazel Wee, Zhanfeng Cui, and Hua Ye. "Towards Ready-to-Use Iron-Crosslinked Alginate Beads as Mesenchymal Stem Cell Carriers." Bioengineering 10, no. 2 (2023): 163. http://dx.doi.org/10.3390/bioengineering10020163.

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Micro-carriers, thanks to high surface/volume ratio, are widely studied as mesenchymal stem cell (MSCs) in vitro substrate for proliferation at clinical rate. In particular, Ca-alginate-based biomaterials (sodium alginate crosslinked with CaCl2) are commonly investigated. However, Ca-alginate shows low bioactivity and requires functionalization, increasing labor work and costs. In contrast, films of sodium alginate crosslinked with iron chloride (Fe-alginate) have shown good bioactivity with fibroblasts, but MSCs studies are lacking. We propose a first proof-of-concept study of Fe-alginate bea

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OYEAGU, UCHENNA, CHARLES NWUCHE, CHRISTIAN OGBONNA, and JAMES OGBONNA. "Amylase Production by Aspergillus niger immobilized in Microporous Calcium Alginate Gel Beads." Romanian Biotechnological Letters 26, no. 4 (2021): 2825–33. http://dx.doi.org/10.25083/rbl/26.4/2825-2833.

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Microporous calcium alginate gel beads were investigated as potential solutions to mass transfer limitations in immobilized cultures. The beads were prepared by gelling mixtures of sodium alginate and fillers (starch or granulated sugars) in calcium chloride solution. The resulting beads were cured in the same solution, during which the fillers leached out of the beads thereby creating micro-pores in the beads (microporous beads). The effectiveness of the microporous beads in improving amylase production by Aspergillus niger LC 269109 was investigated. Spores of A. niger were immobilized in th

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CHERIAN, ABIYA SARA, G. Boby Johns, R. Praveen Raj, P. A. Daisy, and Samuel Jeny. "Formulation and Evaluation of FSM-Alginate Beads of Vildagliptin." Journal of Drug Delivery and Therapeutics 9, no. 4-A (2019): 246–51. http://dx.doi.org/10.22270/jddt.v9i4-a.3289.

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Many approaches have been immerged to prolong the residence time of the dosage forms at the absorption site .One among them is the development of oral controlled release mucoadhesive system. The present study aims to formulate and evaluate the effectiveness of FSM-Alginate beads of Vildagliptin in streptozotocin induced diabetic rats. In the present work, 6 formulations of Vildagliptin mucoadhesive beads (F1 to F6) were prepared by ionotropic gelation method. Fenugreek seed mucilage and sodium alginate was used as polymers and calcium chloride as cross linking agent. The beads containing drugs

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29

Ducci, Matthias. "Redox Reactions in Sodium Alginate Beads." World Journal of Chemical Education 7, no. 2 (2019): 40–44. http://dx.doi.org/10.12691/wjce-7-2-2.

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Moe, Størker T., Gudmund Skjåk-Bræk, and Olav Smidsrød. "Covalently cross-linked sodium alginate beads." Food Hydrocolloids 5, no. 1-2 (1991): 119–23. http://dx.doi.org/10.1016/s0268-005x(09)80296-8.

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Dieni, Anida, and Ustadi. "Immobilization of Bacterial Cells and Chitinolytic Activity of Streptomyces sp. (PB 2)." E3S Web of Conferences 147 (2020): 03032. http://dx.doi.org/10.1051/e3sconf/202014703032.

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This study was aimed to immobilize the chitinolytic bacteria Streptomyces sp. PB 2 using sodium alginate as immobilization agent. Streptomyces sp. PB 2 was reported have a good chitinolytic activity and immobilization is known to increase the stability of bacteria during repeated used. Sodium alginate has been used on several methods of immobilization and sodium alginate are reported as a good agent. Cell immobilization was done by growing the cell on nutrient broth (NB), mixed with 1% sodium alginate to form the beads, then the mixture were put to a syringe and droped into CaCl2 solution. The

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Khalil, Khalilah Abdul, Suhaimi Mustafa, Rosfarizan Mohammad, et al. "Encapsulation of Bifidobacterium pseudocatenulatum Strain G4 within Bovine Gelatin-Genipin-Sodium Alginate Combinations: Optimisation Approach Using Face Central Composition Design-Response Surface Methodology (FCCD-RSM)." International Journal of Microbiology 2019 (April 10, 2019): 1–11. http://dx.doi.org/10.1155/2019/4208986.

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Bovine gelatin is a biopolymer which has good potential to be used in encapsulating matrices for probiotic candidate Bifidobacterium pseudocatenulatum strain G4 (G4) because of its amphoteric nature characteristic. Beads were prepared by the extrusion method using genipin and sodium alginate as a cross-linking agent. The optimisation of bovine gelatin-genipin-sodium alginate combinations was carried out using face central composition design (FCCD) to investigate G4 beads’ strength, before and after exposed to simulated gastric (SGF), intestinal fluids (SIF), and encapsulation yield. A result o

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Samad, Hamizah Abdul, Norinsafrina Kamal, and Siti Mazatul Azwa Saiyed Mohd Nurddin. "Preparation and Characterization of Sodium Alginate Based Composite Beads for Manganese Removal." Key Engineering Materials 974 (February 16, 2024): 39–45. http://dx.doi.org/10.4028/p-c5w8ok.

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The main objective of this study was to characterize and investigate the performance of sodium alginate (SA)-based composite beads as adsorbents for manganese removal from the aqueous solution. In this study, 2% (w/v) of sodium alginate solution was prepared. The SA beads, SA-PCC (SA-P) beads, SA-BMnO (SA-B) beads, and SA-PCC-BMnO (SA-PB) beads were formed by mixing with ionic gelation in a crosslink solution of calcium chloride (CaCl2). The composite beads were characterized using FESEM and thermogravitmetry analysis (TGA). According to FESEM micrographs, all the adsorbents were spherical in

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Sirisha., Y. "Formulation And Evaluation of Chlorhexidine, Aloe Vera Gel Sodium Alginate Beads Incorporated Gel for Topical Application." International Journal of Pharmacy and Biological Sciences (IJPBS) 14, no. 3 (2024): 72–78. https://doi.org/10.5281/zenodo.13842654.

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AbstractThe aim of this project was to develop a novel gel formulation by incorporating chlorhexidine, aloe vera, and sodium alginate beads, and to evaluate its properties for potential pharmaceutical and therapeutic applications. The gel was formulated using aloe vera gel as the base, incorporating chlorhexidine as the antimicrobial agent, and sodium alginate beads for sustained release. The formulation process involved optimizing the concentrations of each component to achieve desired viscosity, drug release profile, and stability. Various physicochemical properties of the gel were evaluated

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Mossa, Zaied A., Faris Hamood Mohammed, Aseel M. Aljeboree, and Ayad F. Alkaim. "Synthesis of a Green Adsorbent Surface Gels: Development of Ratio Preparation of Polymer SA/Bentonite Bead, and its Industrial Applications for Removal of Aqueous Pollutants." Asian Journal of Water, Environment and Pollution 21, no. 1 (2024): 35–44. http://dx.doi.org/10.3233/ajw240006.

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In this research, polymer gels sodium alginate/bentonite clay adsorbent beads (SA/Ben) were prepared via encapsulating natural bentonite (Bn) in sodium alginate (SA). The ratio of Polymer Gels SA/Bn was used during preparation bead to yield beads (1/1 w/w), SA-Bn2 (1/2 w/w), and SA-Bn3 (1/3 w/w), respectively. These adsorbents were characterized via different characterisation FESEM, TEM, XRD and EDX to give high confidence of the prepared surface. The adsorption of Clonazepam drug (CLZ) from aqueous solution on the SA/Bn beads was investigated as a function of different factors, including the

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Prasetyaningrum, A., N. Rokhati, M. Djaeni, et al. "Effect of cross-linking agents on sodium alginate-based quercetin beads: physicochemical properties and controlled release kinetics." Food Research 8, Supplementary 1 (2024): 67–77. http://dx.doi.org/10.26656/fr.2017.8(s1).10.

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Alginates have a variety of biological, physical, and chemical properties that can be modified to meet a specific purpose. Ionic crosslinking is an easy method of alginate modification. This study examined the ionic crosslinking agents (Ca2+, Ba2+, Mg2+) on swelling ratio, water solubility, and % sol-gel fraction of modified alginate. The performance of the modified alginate used to encapsulate quercetin, such as % encapsulation efficiency (% EE), % release of quercetin, and quercetin release kinetics were examined. The variables used in this study were the concentration of alginate and ionic

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Li, Zhao Qing, Li Da Hou, Zhen Li, Wei Zheng, and Li Li. "Study on Shape Optimization of Calcium–Alginate Beads." Advanced Materials Research 648 (January 2013): 125–30. http://dx.doi.org/10.4028/www.scientific.net/amr.648.125.

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In this paper, calcium–alginate beads have been manufactured by physically cross-linked technology, by dripping an aqueous alginate solution into a solution of calcium salt as a crosslinker. The effect of various elements controlling beads shape such as solution concentration, flow rate and the distance between the orifice tip and surface of the cross-linking solution were studied. The various elements affected the gelling rate and diameter and weight were studied. The findings indicated that shape of alginate beads in the hydrated state was strongly dependent on the flow rate and concentratio

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Heinemann, Matthias, Holger Meinberg, Jochen Büchs, Hans-Jürgen Koß, and Marion B. Ansorge-Schumacher. "Method for Quantitative Determination of Spatial Polymer Distribution in Alginate Beads Using Raman Spectroscopy." Applied Spectroscopy 59, no. 3 (2005): 280–85. http://dx.doi.org/10.1366/0003702053585363.

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A new method based on Raman spectroscopy is presented for noninvasive, quantitative determination of the spatial polymer distribution in alginate beads of approximately 4 mm diameter. With the experimental setup, a two-dimensional image is created along a thin measuring line through the bead comprising one spatial and one spectral dimension. For quantitative analysis of the Raman spectra, the method of indirect hard modeling was applied to make use of the information contained in the entire recorded spectra. For quantification of the alginate signals from within the beads, a calibration curve

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Zakhi, Wan Ahmad Mustaqim Ahmad, and Maizlinda Izwana Idris. "Fabrication and Characterization of Alginate/Iron (III) Oxide Beads and Biofilm for Biomedical Applications." Key Engineering Materials 908 (January 28, 2022): 177–82. http://dx.doi.org/10.4028/p-3z7053.

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This research study focused on the fabrication and characterization of sodium alginate incorporated with iron (III) oxide in the form of beads and biofilm for biomedical application. The fabrication of the samples was carried out by using solution casting method and syringe pump extrusion technique. Beads and biofilm of sodium alginate incorporated with iron oxide were characterized by several characterization testing such as XRD, FTIR and contact angle measurement. From the XRD testing shows the diffraction peak that confirmed the cubic structure of Maghemite. Then, FTIR analysis shows the pr

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Petkova, N. T., Kr T. Nikolova, G. D. Gentscheva, et al. "Effect of different hydrocolloids on Ca (II) – alginate beads containing extracts from Arthrospira platensi." Bulgarian Chemical Communications 56, no. D1 (2024): 158–62. http://dx.doi.org/10.34049/bcc.56.d.s1p72.

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Alginate was applied in food matrix, and pharmaceutical products for efficient encapsulation of bioactive compounds or as a drug carrier. In the current study phycocyanin isolated from dry Arthrospira platensis/Spirulina was encapsulated in alginate beads. The aim of the current research was to evaluate the effect of different hydrocolloids (inulin, pectin and guar) at different pH values and temperatures on phycocyanin content in the alginate beads. The alginate microspheres were formed with 1% sodium alginate, 6% sucrose, 1% phycocyanin, and selected hydrocolloids, as neutral polysaccharides

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Mansfield, John, Petra Eiselt, Julia Yeh, and David J. Mooney. "Environmental SEM Study of Sodium Alginate Beads." Microscopy and Microanalysis 5, S2 (1999): 300–301. http://dx.doi.org/10.1017/s1431927600014823.

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A variety of porous materials are used in a number of tissue-engineering applications such as cell transplantation and drug delivery. They provide a temporary scaffolding for a large cell mass, however they must have a fully interconnected pore structure. One such material is sodium alginate, a naturally derived polysaccharide which is isolated from seaweed. Sodium alginate can de dissolved in water to form a highly viscous solution that can be cross-linked in the presence of divalent cations (e.g., Ca2+) to form what is known a as hydrogels. We have developed a method for the fabrication of p

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., Sutriyo, Raditya Iswandana, and Fauzana Fauzi. "STRATEGY TO MASK THE BITTER TASTE OF MOMORDICA CHARANTIA EXTRACT USING ALGINATE–GELATIN BEADS." International Journal of Applied Pharmaceutics 10, no. 1 (2018): 381. http://dx.doi.org/10.22159/ijap.2018.v10s1.84.

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Objective: This study is aimed to develop a strategy to mask the bitter taste of Momordica charantia Linn. extract using alginate–gelatin beads.Methods: Beads of bitter melon fruit extract (M. charantia Linn) were prepared using an ionic gelation method in which cross-linking occurs betweensodium alginate and calcium chloride that serves to mask the bitter taste. Beads were prepared using sodium alginate (1.5% w/v) with variousconcentrations of bitter melon fruit extract (1:2, 1:1, and 1:0.5), gelatin (2% w/v), and CaCl2 3%. The obtained beads were then characterized bothphysically and functio

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Hosokawa, Yuhei, Takashi Goshima, Takami Kai, et al. "Preparation of Alginate Hydrogel Beads on a Superhydrophobic Surface with Calcium Salt Powder to Enhance the Mechanical Strength and Encapsulation Efficiency of Ingredients." Materials 17, no. 24 (2024): 6027. https://doi.org/10.3390/ma17246027.

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Calcium alginate hydrogel is one of the most widely used materials for drug-carrier beads used in drug-delivery systems. In this study, we developed a new method to improve the encapsulation efficiency of ingredients, such as medicines, in calcium alginate hydrogel beads. In the gold standard method, the hydrogel beads are prepared in the liquid phase. In contrast, in the new method, to enhance the encapsulation efficiency, the hydrogel beads are prepared in the gas phase using a water-repellent surface. In brief, a droplet of sodium alginate aqueous solution is rolled on a water-repellent sur

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Sriraksa, S., N. Sermkaew, S. Setthacheewakul, and R. Wiwattanapatapee. "Floating Alginate Beads as Carriers for Self-Emulsifying System Containing Tetrahydrocurcumin." Advanced Materials Research 506 (April 2012): 517–20. http://dx.doi.org/10.4028/www.scientific.net/amr.506.517.

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Tetrahydrocurcumin (THC), one of the curcumin metabolites, exhibits pharmacological activities such as antioxidant, anti-inflammatory and anti-carcinogenic properties. However, the pharmacological effect of THC is limited due to its low aqueous solubility. Floating alginate beads containing self-emulsifying drug delivery system (SEDDS) of THC were developed to increase drug solubility and prolong gastric residence time. Use of different weight proportions of sodium alginate (Na-alg.), calcium chloride (CaCl2) and water soluble pore former (Polyvinylalcohol-polyethylene glycol copolymer; Kollic

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Xing, Nan, Yu Kun Li, Meng Su Li, and Feng Tian. "Insight into Effects of Different Drying Methods on Morphological Properties of Sodium Alginate-Chitosan Double Coacervation Hydrogel Beads." Applied Mechanics and Materials 184-185 (June 2012): 1025–29. http://dx.doi.org/10.4028/www.scientific.net/amm.184-185.1025.

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Hydrogel beads with different diameters were prepared by double coacervation method of alginate with CaCl2 followed by complexation between alginate and chitosan. The main purpose of this study was to evaluate the morphological properties of beads under different conditions and prepared by different drying methods, which would have a major effect on the other characters and applications of beads. The results show that the beads can be manufactured with the control of concentrations of the two polymers and diameter of the syringe needle. Different drying methods can affect the morphological pro

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Zam, Wissam, Ghada Bashour, Wassim Abdelwahed, and Warid Khayata. "Alginate-pomegranate peels' polyphenols beads: effects of formulation parameters on loading efficiency." Brazilian Journal of Pharmaceutical Sciences 50, no. 4 (2014): 741–48. http://dx.doi.org/10.1590/s1984-82502014000400009.

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Calcium alginate beads containing pomegranate peels' polyphenol extract were encapsulated by ionic gelation method. The effects of various formulation factors (sodium alginate concentration, calcium chloride concentration, calcium chloride exposure time, gelling bath time maintaining, and extract concentration) on the efficiency of extract loading were investigated. The formulation containing an extract of 1 g pomegranate peels in 100 mL distilled water encapsulated with 3 % of sodium alginate cured in 0.05 M calcium chloride for 20 minutes and kept in a gelling bath for 15 minutes was chosen

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Hu, Miao, Xiaoqian Du, Guannan Liu, Yuyang Huang, Baokun Qi, and Yang Li. "Sodium alginate/soybean protein–epigallocatechin-3-gallate conjugate hydrogel beads: evaluation of structural, physical, and functional properties." Food & Function 12, no. 24 (2021): 12347–61. http://dx.doi.org/10.1039/d1fo03099j.

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Ji, Xiang, Di Wu, Yongqiang Wang, et al. "Fabrication of lanthanum-based phosphate binder using cross-linked alginate as a carrier." RSC Advances 5, no. 68 (2015): 55191–200. http://dx.doi.org/10.1039/c5ra03941j.

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Iskakov, R. M., E. O. Batyrbekov, B. A. Zhubanov, et al. "Immobilization of Analgetic AB-101 into Calcium Alginate Gels." Eurasian Chemico-Technological Journal 4, no. 4 (2017): 293. http://dx.doi.org/10.18321/ectj547.

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<p>A new analgetic drug AB-101 has been immobilized into Ca<sup>2+</sup>-alginate gel beads with average diameter of 1 mm. A series of the alginate gel contains with various mannuronic/guluronic (M/G) ratios has been chosen to control the diffusion of the drug. Release of the drug from the alginate gel beads into physiological solutions consisting of sodium ions has been examined. A discontinuous time of the Fickian diffusion of the drug depending on M/G ratio was followed by a burst release of the remaining drugs. The burst release was due to a swift disintegration of Ca<

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Kim, Jinwon, Ivan Hiltpold, Geoffrey Jaffuel, Ilham Sbaiti, Bruce E. Hibbard, and Ted C. J. Turlings. "Calcium-alginate beads as a formulation for the application of entomopathogenic nematodes to control rootworms." Journal of Pest Science 94, no. 4 (2021): 1197–208. http://dx.doi.org/10.1007/s10340-021-01349-4.

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AbstractEntomopathogenic nematodes (EPN) have great potential as biological control agents against root-feeding insects. They have a rapid and long-lasting mode of action, minimal adverse effects on the environment and can be readily mass-produced. However, they have a relatively short shelf-life and are susceptible to desiccation and UV light. These shortcomings may be overcome by encapsulating EPN in Ca2+-alginate hydrogels, which have been shown to provide a humid and UV protective shelter. Yet, current Ca2+-alginate formulations do not keep EPN vigorous and infectious for a prolonged perio

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