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1

MONTVILLE, THOMAS J., and PETER K. GOLDSTEIN. "Sodium Bicarbonate Inhibition of Aflatoxigenesis in Corn." Journal of Food Protection 52, no. 1 (January 1, 1989): 45–48. http://dx.doi.org/10.4315/0362-028x-52.1.45.

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This study sought to determine if the ability of sodium bicarbonate and ammonium bicarbonate to inhibit aflatoxigenesis in microbiological media could be extended to corn systems. A method for applying bicarbonates evenly to corn was developed. Aflatoxin levels of sodium bicarbonate-treated (0.17 % wt/wt) corn were reduced to one-third those of untreated corn when both were inoculated with Aspergillus parasiticus spores and incubated at 30°C for three weeks. While both sodium and ammonium bicarbonate reduced the amount of fungal growth, only sodium bicarbonate reduced aflatoxin production.
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2

&NA;. "Sodium bicarbonate see Hydrocortisone/sodium bicarbonate." Reactions Weekly &NA;, no. 315 (August 1990): 7. http://dx.doi.org/10.2165/00128415-199003150-00033.

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3

&NA;. "Sodium bicarbonate." Reactions Weekly &NA;, no. 1189 (February 2008): 30–31. http://dx.doi.org/10.2165/00128415-200811890-00097.

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4

&NA;. "Sodium bicarbonate." Reactions Weekly &NA;, no. 1129 (November 2006): 19–20. http://dx.doi.org/10.2165/00128415-200611290-00063.

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5

&NA;. "Sodium bicarbonate." Reactions Weekly &NA;, no. 1148 (April 2007): 31. http://dx.doi.org/10.2165/00128415-200711480-00098.

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6

&NA;. "Sodium bicarbonate." Reactions Weekly &NA;, no. 1241 (February 2009): 36. http://dx.doi.org/10.2165/00128415-200912410-00103.

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7

&NA;. "Sodium bicarbonate." Reactions Weekly &NA;, no. 1328 (November 2010): 40. http://dx.doi.org/10.2165/00128415-201013280-00140.

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8

Barna, Peter. "Sodium Bicarbonate." Journal of Clinical Gastroenterology 8, no. 6 (December 1986): 697. http://dx.doi.org/10.1097/00004836-198612000-00028.

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9

DEPASQUALE, DAVID A., ANWAAR EL-NABARAWY, JOSEPH D. ROSEN, and THOMAS J. MONTVILLE. "Ammonium Bicarbonate Inhibition of Mycotoxigenic Fungi and Spoilage Yeasts." Journal of Food Protection 53, no. 4 (April 1, 1990): 324–28. http://dx.doi.org/10.4315/0362-028x-53.4.324.

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Sodium bicarbonate inhibits growth and aflatoxin production by Aspergillus parasiticus. This survey determined that other mycotoxigenic fungi were also sensitive to bicarbonates. Sodium bicarbonate, potassium bicarbonate, ammonium bicarbonate, ammonium sulfate, and sodium chloride were added to buffered or unbuffered potato-dextrose agar to determine the bicarbonate effect on growth and morphology of six mycotoxigenic fungi. Three nonmycotoxigenic fungi and four yeast species were also examined. Ammonium bicarbonate at 0.11M completely inhibited the growth of Fusarium tricinctum NRRL 13442, F. tricinctum NRRL 13426, F. graminearum NRRL 5883, F. sporotrichioides NRRL 3249, Penicillium griseofulvum NRRL 989, Aspergillus ochraceus NRRL 3174, A. flavus NRRL 1957, A. niger, and P. notatum. Sodium chloride and pH elevated through the use of ampso-NaOH, capso-NaOH, or glycine-NaOH buffer did not display an inhibitory effect on the filamentous fungi examined. Buffered ammonium sulfate treatments (pH approximately 9.0) completely inhibited all of the mycotoxigenic fungi, but at pH 5.6, ammonium sulfate treatments were not inhibitory. Sodium bicarbonate (0.11M) was effective only against P. griseofulvum, A. flavus NRRL 1957, A. niger, and P. notatum, causing viability reductions of 5.6, 3.7, 4.9, and 2.9 log cycles, respectively. Potassium bicarbonate was generally as inhibitory as the sodium salt. In contrast, elevated pH, alone, appeared to account for the >6 log reduction observed for the yeasts Lipomyces starkeyi, Geotrichum candidum, Kluyveromyces marxianus, and Debaryomyces hansenii.
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10

Velissaris, Dimitrios, Vasilios Karamouzos, Nikolaos Ktenopoulos, Charalampos Pierrakos, and Menelaos Karanikolas. "The Use of Sodium Bicarbonate in the Treatment of Acidosis in Sepsis: A Literature Update on a Long Term Debate." Critical Care Research and Practice 2015 (2015): 1–7. http://dx.doi.org/10.1155/2015/605830.

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Introduction. Sepsis and its consequences such as metabolic acidosis are resulting in increased mortality. Although correction of metabolic acidosis with sodium bicarbonate seems a reasonable approach, there is ongoing debate regarding the role of bicarbonates as a therapeutic option.Methods. We conducted a PubMed literature search in order to identify published literature related to the effects of sodium bicarbonate treatment on metabolic acidosis due to sepsis. The search included all articles published in English in the last 35 years.Results. There is ongoing debate regarding the use of bicarbonates for the treatment of acidosis in sepsis, but there is a trend towards not using bicarbonate in sepsis patients with arterial blood gaspH>7.15.Conclusions. Routine use of bicarbonate for treatment of severe acidemia and lactic acidosis due to sepsis is subject of controversy, and current opinion does not favor routine use of bicarbonates. However, available evidence is inconclusive, and more studies are required to determine the potential benefit, if any, of bicarbonate therapy in the sepsis patient with acidosis.
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11

REQUENA, BERNARDO, MIKEL ZABALA, PAULINO PADIAL, and BELÉN FERICHE. "SODIUM BICARBONATE AND SODIUM CITRATE." Journal of Strength and Conditioning Research 19, no. 1 (February 2005): 213–24. http://dx.doi.org/10.1519/00124278-200502000-00036.

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12

&NA;. "Sodium bicarbonate overdose." Reactions Weekly &NA;, no. 1204 (May 2008): 30. http://dx.doi.org/10.2165/00128415-200812040-00096.

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13

&NA;. "Sodium bicarbonate abuse." Reactions Weekly &NA;, no. 1259 (July 2009): 26. http://dx.doi.org/10.2165/00128415-200912590-00076.

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14

&NA;. "Sodium bicarbonate overdose." Reactions Weekly &NA;, no. 297 (April 1990): 11. http://dx.doi.org/10.2165/00128415-199002970-00056.

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15

&NA;. "Hydrocortisone/sodium bicarbonate." Reactions Weekly &NA;, no. 315 (August 1990): 6. http://dx.doi.org/10.2165/00128415-199003150-00021.

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16

Koziris, Lymperis (Perry). "Sodium Bicarbonate Supplementation." Strength and Conditioning Journal 34, no. 4 (August 2012): 21. http://dx.doi.org/10.1519/ssc.0b013e318259401a.

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17

Hughes, R. L. "Sodium bicarbonate solutions." Anaesthesia 43, no. 1 (January 1988): 72. http://dx.doi.org/10.1111/j.1365-2044.1988.tb05459.x.

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18

"Sodium-bicarbonate." Reactions Weekly 1854, no. 1 (May 2021): 324. http://dx.doi.org/10.1007/s40278-021-95655-6.

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19

"Sodium-bicarbonate." Reactions Weekly 1922, no. 1 (September 3, 2022): 530. http://dx.doi.org/10.1007/s40278-022-22815-z.

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20

"Sodium-bicarbonate." Reactions Weekly 1895, no. 1 (February 2022): 341. http://dx.doi.org/10.1007/s40278-022-10766-6.

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21

"Sodium-bicarbonate." Reactions Weekly 1901, no. 1 (April 2022): 428. http://dx.doi.org/10.1007/s40278-022-13105-2.

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22

"Sodium-bicarbonate." Reactions Weekly 1926, no. 1 (October 1, 2022): 431. http://dx.doi.org/10.1007/s40278-022-24709-9.

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23

"Sodium bicarbonate." Reactions 270, no. 1 (September 1989): 8. http://dx.doi.org/10.1007/bf03281649.

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24

"Sodium-bicarbonate." Reactions Weekly 1707, no. 1 (June 2018): 253. http://dx.doi.org/10.1007/s40278-018-48069-z.

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25

"Sodium bicarbonate." Reactions Weekly 1722, no. 1 (October 2018): 316. http://dx.doi.org/10.1007/s40278-018-52645-3.

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26

"Sodium bicarbonate." Reactions Weekly 1633, no. 1 (January 2017): 646. http://dx.doi.org/10.1007/s40278-017-24913-y.

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27

"Sodium bicarbonate." Reactions Weekly 1685, no. 1 (January 2018): 187. http://dx.doi.org/10.1007/s40278-018-41046-9.

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28

"Sodium-bicarbonate." Reactions Weekly 1768, no. 1 (August 2019): 305. http://dx.doi.org/10.1007/s40278-019-66989-y.

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29

"Sodium bicarbonate." Reactions Weekly 1651, no. 1 (May 2017): 292. http://dx.doi.org/10.1007/s40278-017-30104-x.

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30

"Sodium-bicarbonate." Reactions Weekly 1731, no. 1 (December 2018): 240. http://dx.doi.org/10.1007/s40278-018-55435-z.

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31

"Sodium bicarbonate." Reactions Weekly 1823, no. 1 (September 2020): 318. http://dx.doi.org/10.1007/s40278-020-83946-3.

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32

"Sodium bicarbonate." Reactions Weekly 1479, no. 1 (November 2013): 28. http://dx.doi.org/10.1007/s40278-013-7362-6.

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33

"Sodium bicarbonate." Reactions Weekly 1579, no. 1 (November 2015): 363. http://dx.doi.org/10.1007/s40278-015-11322-6.

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34

"Sodium bicarbonate." Reactions Weekly 1541, no. 1 (March 2015): 230. http://dx.doi.org/10.1007/s40278-015-8382-1.

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35

"Sodium-bicarbonate." Reactions Weekly 1741, no. 1 (February 2019): 217. http://dx.doi.org/10.1007/s40278-019-58449-x.

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36

"Sodium bicarbonate." Reactions Weekly 1705, no. 1 (June 2018): 289. http://dx.doi.org/10.1007/s40278-018-47304-2.

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37

"Sodium-bicarbonate." Reactions Weekly 1812, no. 1 (July 2020): 260. http://dx.doi.org/10.1007/s40278-020-80739-4.

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38

"Sodium bicarbonate." Reactions Weekly 1748, no. 1 (April 2019): 482. http://dx.doi.org/10.1007/s40278-019-60396-1.

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39

"Sodium bicarbonate." Reactions Weekly 1958, no. 1 (May 27, 2023): 463. http://dx.doi.org/10.1007/s40278-023-40137-4.

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40

"Sodium bicarbonate." Reactions Weekly 1944, no. 1 (February 18, 2023): 511. http://dx.doi.org/10.1007/s40278-023-34030-y.

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41

"Sodium-bicarbonate." Reactions Weekly 1931, no. 1 (November 5, 2022): 528. http://dx.doi.org/10.1007/s40278-022-27325-6.

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42

"Sodium-bicarbonate." Reactions Weekly 2005, no. 1 (April 27, 2024): 739. http://dx.doi.org/10.1007/s40278-024-57832-z.

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43

"Sodium-bicarbonate." Reactions Weekly 2010, no. 1 (June 1, 2024): 364. http://dx.doi.org/10.1007/s40278-024-60206-5.

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44

"Sodium-bicarbonate/sodium-dichloroacetate." Reactions Weekly 1934, no. 1 (November 26, 2022): 386. http://dx.doi.org/10.1007/s40278-022-28767-4.

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45

"Sodium acetate/sodium bicarbonate." Reactions Weekly 1676, no. 1 (November 2017): 266. http://dx.doi.org/10.1007/s40278-017-38254-5.

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46

"Sodium bicarbonate/sodium chloride." Reactions Weekly 1758, no. 1 (June 2019): 320. http://dx.doi.org/10.1007/s40278-019-63866-y.

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47

"5: Final Report on the Safety Assessment of Sodium Sesquicarbonate, Sodium Bicarbonate, and Sodium Carbonate." Journal of the American College of Toxicology 6, no. 1 (January 1987): 121–38. http://dx.doi.org/10.3109/10915818709095491.

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Sodium Sesquicarbonate, Sodium Carbonate, and Sodium Bicarbonate are used in cosmetic products at concentrations ranging up to 50%. The LD50 in rats for Sodium Bicarbonate ranged from 7.6 g/kg to 8.9 g/kg. Sodium Sesquicarbonate, Sodium Carbonate, and Sodium Bicarbonate caused conjunctivitis. Sodium Bicarbonate was not an ocular irritant to laboratory animals. Neither Sodium Bicarbonate nor Sodium Carbonate was a teratogen to laboratory animals. Sodium Sesquicarbonate and Sodium Bicarbonate were not mutagenic to two different cell cultures. Dermatitis, but not sensitization, was observed in employees of a Trona (Sodium Sesquicarbonate) mining facility. Sodium Carbonate, but not Sodium Bicarbonate, is a skin and eye irritant due to the alkaline nature of its solutions, The cosmetic use of Sodium Carbonate at high concentrations is mainly limited to products designed to be diluted before use and in products where pH is buffered to near neutrality. It is concluded that Sodium Sesquicarbonate, Sodium Bicarbonate, and Sodium Carbonate are safe as presently used in cosmetics.
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48

"Epinephrine/sodium bicarbonate/sodium chloride." Reactions Weekly 1927, no. 1 (October 8, 2022): 251. http://dx.doi.org/10.1007/s40278-022-24987-x.

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49

"Insulin/sodium bicarbonate/sodium chloride." Reactions Weekly 1918, no. 1 (August 6, 2022): 273. http://dx.doi.org/10.1007/s40278-022-20730-5.

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50

"Sodium bicarbonate/sodium chloride/dexamethasone." Reactions Weekly 1479, no. 1 (November 2013): 29. http://dx.doi.org/10.1007/s40278-013-7364-4.

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