Relevant bibliographies by topics / Sodium humate

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Sodium humate'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Sodium humate"

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Dzhusipbekov, U. Zh, G. O. Nurgalieva, Z. K. Bayakhmetova, and A. K. Shakirova. "OBTAINING HUMATE-CONTAINING NEW COMPOSITE PRODUCTS." Chemical Journal of Kazakhstan 3 (September 30, 2021): 5–18. http://dx.doi.org/10.51580/2021-1/2710-1185.35.

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The influence of various factors on the process of interaction in the systems "sodium humate-mixture of phosphoric and nitric acids" and "phosphorite-mixture of acids-sodium humate" has been investigated. The influence of the ratios of the initial components, the amount of sodium humate introduced, the rate of the acid reagent, the temperature and duration of the reaction on the interaction process in the systems under study was studied, and the optimal process conditions were determined. The methods of chemical and physicochemical analysis revealed that as a result of interaction in the studi
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Nurgalieva, G., U. Dzhussipbekov, Z. Bayakhmetova, D. Duisenbai, and U. Aksakalova. "INFLUENCE OF SODIUM HUMATE CONCENTRATIONS ON THE COMPOSITION AND PROPERTIES OF LIQUID ORGANOMINERAL FERTILIZERS." Chemical Journal of Kazakhstan, no. 2 (June 30, 2025): 15–24. https://doi.org/10.51580/2025-2.2710-1185.18.

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Introduction. The use of liquid organomineral fertilizers (LOMF) based on chelates of microelements and humates leads not only to an increase in yield and product quality, but also to a decrease in economic costs. LOMF s have a complex effect on plants, activate various physiological processes, increase the plant defense mechanism to various stresses and phytopathogens, improve the structure and properties of the soil. The aim of the work is to study the patterns of the influence of sodium humate concentrations on the process of obtaining humate-, nitrogen- and molybdenum-containing LOMFs. Met
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Juraja, Krystyna. "Influence of sodium humate on the growth of Scenedesmus quadricauda (Turp. Brèb.) and Gonium pectorale in the case of different calciumand iron doses." Acta Societatis Botanicorum Poloniae 43, no. 4 (2015): 519–30. http://dx.doi.org/10.5586/asbp.1974.051.

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The influence of sodium humate on calcium and iron uptake by two species of algae was studied. It was found that sodium humate influence differentially the growth of these algae in various culture conditions by regulating the iron uptake. The action of sodium humate is especially favourable in non optimal pH of the medium and its effectiveness increases with time.
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Lisik, Maria J. "The effect of sodium humane on the growth of tomatoes and the accumulation of phosphorus and iron in mediums of different pH." Acta Societatis Botanicorum Poloniae 53, no. 3 (2014): 377–83. http://dx.doi.org/10.5586/asbp.1984.033.

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The effect of sodium humate on changes in the phosphorus and iron content in shoots of tomatoes cultivated in mediums with a raised or lowered pH and phosphorus dose (compared with controls) were analysed. At low pH, sodium humate increased the accumulation of phosphorus and lessened the excessive accumulation of iron in plants cultivated under conditions of phosphours deficit. At a slightly alkaline pH, sodium humate prevented excessive, accumulation of phosphorus and raised low iron contents. A favorable effect of humate on dry mass production was clearly seen at pH 6.4.
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Asanov, R., U. Abdaliev та I. Tashpolotov. "Investigation of the dependence of the specific electrical conductivity of low-concentrated water-coal suspension (WСS) from the concentration of the sodium humate reagent and from the concentration of the solid phase of suspensions". Bulletin of Science and Practice, № 12 (14 грудня 2017): 257–62. https://doi.org/10.5281/zenodo.1115888.

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In this article is considered comprehensive research: 1) dependence of the specific electrical resistance of the WCS with an increase in the concentration of the sodium humate reagent–plasticizer at a constant solid phase of the WCS 2) dependence of specific electric resistance of WCS at an increase in her firm phase without sodium humate reagent. At first sodium humate reagent with mass fractions from 10% up to 50% of the mass of firm phase WCS is added to WCS with a concentration of firm phases of 10%, 30% and 50% and for each case, volt the ampere parameters are separately m
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Kováčik, Peter, Alžbeta Žofajová, Vladimír Šimanský, and Klaudia Halászová. "Spring Barley Yield Parameters after Lignite, Sodium Humate and Nitrogen Utilization." Agriculture (Polnohospodárstvo) 62, no. 3 (2016): 80–89. http://dx.doi.org/10.1515/agri-2016-0009.

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Abstract The existence of a small number of publications dealing with the impact of solid sodium humate and lignite on the quantity and quality of grown crops was the reason for establishing the field experiment. The objective of this experiment was to detect the impact of solid lignite and solid sodium humate on the quantity and quality of spring barley yield. These substances were applied into the soil either independently or along with nitrogen fertiliser. The next objective was to determine the impact of foliar application of sodium humate water solution applied either independently or alo
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Zykova, M. V., Yun Zhang, I. V. Lysenko, et al. "Restoring antibiotic sensitivity to lincomycin in compositions with nanosilver and humic substances." Bulletin of Siberian Medicine 23, no. 2 (2024): 55–64. http://dx.doi.org/10.20538/1682-0363-2024-2-55-64.

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Aim. To study the effect of compositions with nanosilver and humic substances on restoration of sensitivity of methicillin-resistant Staphylococcus aureus to lincomycin. Materials and methods. Compositions of humic substances with silver nanoparticles were synthesized from commercial sodium humate Powhumus and silver nitrate in the presence of NaOH (1 M) to modulate alkaline pH. To synthesize one of the two compositions, sodium humate was modified with hydroquinone. To describe the characteristics of the resulting compositions, surface plasmon resonance spectra of silver nanoparticles and thei
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Shkarupa, V. M., and S. V. Klymenko. "RADIOPROTECTIVE PROPERTIES OF SODIUM HUMATE IN RADIATION-INDUCED MUTAGENESIS IN CULTURED LYMPHOCYTES OF THYROID CANCER PATIENTS." Experimental Oncology 38, no. 2 (2016): 108–11. http://dx.doi.org/10.31768/2312-8852.2016.38(2):108-111.

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Aim: To investigate the effect of sodium humate on the level of cytogenetic damage in culture of lymphocytes of patients with thyroid cancer after γ-irradiation. Materials and Methods: Metaphase analysis of chromosome aberrations in cultured peripheral blood lymphocytes of 10 individuals with thyroid cancer was performed after irradiation of lymphocytes in vitro at a dose of 1 Gy from 137Cs source at the early G0 phase of cell cycle. Sodium humate was added to cell culture for 30 ± 15 min after phytohemagglutinin stimulation at concentrations of 10 and 100 μg/ml. Results: Sodium humate exhibit
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Lisiak, M. J. "The effect of sodium humate upon phosphorus nutrition of plants with variable doses of iron and calcium in tomato water cultures." Acta Societatis Botanicorum Poloniae 47, no. 4 (2015): 429–40. http://dx.doi.org/10.5586/asbp.1978.039.

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Studies were carried out on the effect of sodium humate upon content of P, Fe, Ca, and dry weight yield of tomato seedlings in water cultures. Nutrient solutions contained 10 times more or 10 times less P, Fe, and Ca than the control (nutrient solution according to Hampe). Sodium humate was effective only in relation to phosphorus at lowered amount of Fe, and supplied the plants with Fe when phosphorus content remained in excess. At lowered Ca content humate was not more effective in relation to phosphorus. Sodium humate protected the plants against inhibiting effects of excessive Ca content,
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Jandl, J., and J. Novosad. "Influence of241Am mobility by sodium humate." Journal of Radioanalytical and Nuclear Chemistry Letters 199, no. 2 (1995): 143–49. http://dx.doi.org/10.1007/bf02162477.

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Dissertations / Theses on the topic "Sodium humate"

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Sohraby, Sarah. "Le canal sodium épithélial." Doctoral thesis, Universite Libre de Bruxelles, 1988. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/213399.

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Velho, Albertina Menezes. "Topology of human sodium dependent vitamin C transporters." Thesis, University of Kent, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.405985.

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Robins, Gerard George. "Second messenger regulation of human epithelial sodium channels." Thesis, University of Newcastle Upon Tyne, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.402198.

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Love, Thomas D. "The effect of exercise on sodium balance in humans." Thesis, Loughborough University, 2010. https://dspace.lboro.ac.uk/2134/7072.

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During exercise water and electrolytes are lost in sweat. There is a large variation in both sweat rate and sweat composition and as a consequence sweat electrolyte loss can be large, especially for sodium, the primary cation in sweat. The loss of large amounts of sodium in sweat has been linked with hyponatraemia and muscle cramps. Sodium intake is encouraged in some athletes and in some exercise situations, which is in direct contrast to guidelines aimed at the general population aimed at reducing average sodium intakes to 2.4g of sodium per day (6g salt/day). Dietary sodium intakes have bee
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Hills, Claire Elizabeth. "SGK and disrupted renal sodium handling in diabetes." Thesis, University of Warwick, 2006. http://wrap.warwick.ac.uk/81100/.

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Diabetic nephropathy is associated with secondary hypertension arising from aberrant sodium reabsorption in the kidney. This thesis characterises a novel human cell line derived from the human cortical collecting duct (HCD) to assess glucoseevoked changes in key elements, such as the serum and glucocorticoid inducible kinase (SGKI) and the epithelial sodium channel (ENaC), involved in the regulation of sodium transport. In addition I have also examined the effects of TGF-f3I and [Ci+]i on SGKI and ENaC expression. RT-PCR, western blot analysis, immunocytochemistry and single cell imaging were
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Winski, Shannon Lee 1967. "Metabolism and toxicity of sodium arsenate in human erythrocytes." Diss., The University of Arizona, 1997. http://hdl.handle.net/10150/282320.

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Toxicity of arsenic species is dependent on chemical oxidation state. Inorganic arsenic in the trivalent state, arsenite or As(III), is more biologically active than pentavalent arsenic, arsenate or As(V), and is more toxic by most measures. As(V), however, is more stable and prevalent in the environment. One consequence of environmental exposure is peripheral vascular disease, which is primarily due to vascular changes, but toxicity to the erythrocyte has not been evaluated. To understand toxicity and the implications of arsenic oxidation state, human erythrocytes were utilized to model the u
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Charlton, J. A. "Aspects of sodium and magnesium interrelationships in mammalian absorption and metabolism." Thesis, University of Newcastle Upon Tyne, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.376219.

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Cheung, Kwok-ho Alvin, and 張國豪. "The role of human sodium dicarboxylate cotransporter in oxidative stress." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B27769070.

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Ma, Jie. "Human Endogenous Sodium Pump Inhibitors Measurement, Source, Synthesis and Regulation." BYU ScholarsArchive, 2011. https://scholarsarchive.byu.edu/etd/2953.

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The sodium pump (SP or Na+,K+-ATPase) is a membrane embedded protein complex that pumps 3 sodium ions out and 2 potassium ions into the cell per cycle and in so doing creates a cell membrane electrochemical potential. The membrane potential is critical for any functional cell. In the vasculature, reduction in the voltage potential causes vascular smooth muscle contraction and a narrowing of blood vessels (vasoconstriction) which can lead to increased blood pressure (hypertension). Substantial research over the past several decades has provided a vast amount of research on SP inhibitors, someti
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Scoumanne, Ariane Claire Agnes Ghislaine. "Expression of the cardiac hH1 sodium channel in human vascular endothelium." Thesis, Imperial College London, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.408244.

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Books on the topic "Sodium humate"

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Bryan, Patty. Food values: Fats and cholesterol. HarperPerennial, 1992.

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Bryan, Patty. Food values. Perennial Library, 1990.

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Harris, Thomas. Hannibal Rising. William Heinemann, 2006.

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Harris, Thomas. Hannibal Rising. Dell, 2007.

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Harris, Thomas. Hannibal Rising: A Novel. Random House Large Print, 2006.

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Harris, Thomas. Hannibal Rising. Random House Publishing Group, 2009.

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Harris, Thomas. Hannibal Rising: A novel. Delacorte Press, 2006.

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Harris, Thomas. Hannibal rising: A novel. Dell, 2007.

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Harris, Thomas. Hannibal Rising. Delacorte Press, 2006.

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Harris, Thomas. Hannibal Rising: ハンニバル・ライジング. Shinchōsha, 2007.

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Book chapters on the topic "Sodium humate"

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Tutar, Ahmet, and Mümin Dizman. "A Novel Polymer Blend Based on Sodium Humate/PVP/PEG." In Functions of Natural Organic Matter in Changing Environment. Springer Netherlands, 2012. http://dx.doi.org/10.1007/978-94-007-5634-2_59.

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Hallenbeck, William H., and Kathleen M. Cunningham-Burns. "Sodium Chlorate." In Pesticides and Human Health. Springer New York, 1985. http://dx.doi.org/10.1007/978-1-4612-5054-8_84.

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Hallenbeck, William H., and Kathleen M. Cunningham-Burns. "Sodium Fluoroacetate." In Pesticides and Human Health. Springer New York, 1985. http://dx.doi.org/10.1007/978-1-4612-5054-8_85.

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Ayyash, M., F. Sherkat, and N. Shah. "36. Sodium chloride substitution of cheese." In Human Health Handbooks. Wageningen Academic Publishers, 2013. http://dx.doi.org/10.3920/978-90-8686-766-0_36.

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Heath, Donald, and Paul Smith. "The Carotid Bodies and Sodium Metabolism." In Diseases of the Human Carotid Body. Springer London, 1992. http://dx.doi.org/10.1007/978-1-4471-1874-9_15.

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Hryshko, L. V., and Kenneth D. Philipson. "Sodium-calcium exchange: Recent advances." In Alterations of Excitation-Contraction Coupling in the Failing Human Heart. Steinkopff, 1998. http://dx.doi.org/10.1007/978-3-642-48670-8_6.

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Polat, Elif. "Fat Soluble Vitamins and Macrominerals." In Vitamins, Minerals and Trace Elements. Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053359173.1.

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The word vitamin was first used to mean ""the amine necessary for life"". • Vitamins are organic catalysts necessary for normal body functions, growth and healthy living. They are not synthesized in the human body and must be obtained externally. Vitamins are classified according to their fat and water solubility. Fat-soluble vitamins are vitamins A, D, E and K, and although they are essential for health, each of them has very important functions in the body. They have many biological activities such as vision, bone, coagulation and antioxidant effects. They are released, absorbed and transpor
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Thomson, Neil R. "In Situ Chemical Oxidation of Petroleum Hydrocarbons." In Advances in the Characterisation and Remediation of Sites Contaminated with Petroleum Hydrocarbons. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-34447-3_15.

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AbstractIn situ chemical oxidation (ISCO) is a mature treatment technology that involves the delivery of a chemical oxidant into a target treatment zone (TTZ) to destroy petroleum hydrocarbon (PHC) compounds, and thereby reduce risk to human health and the environment. Commonly used chemical oxidants include hydrogen peroxide, sodium percarbonate, ozone, sodium or potassium permanganate, and sodium or potassium persulfate. All these oxidants can degrade environmentally relevant PHCs except that permanganate is non-reactive toward benzene. Ozone is delivered into the TTZ as a gas while the othe
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Kikuchi, Hiraku, Tohgo Nonaka, Wataru Shimada, et al. "Effects of Sodium Hyaluronic Acid on Fibrinolytic Factors in Humans with Arthropathies." In Advances in Osteoarthritis. Springer Japan, 1999. http://dx.doi.org/10.1007/978-4-431-68497-8_18.

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Pluta, Ryszard M. "Prolonged Intravenous Infusion of Sodium Nitrite Delivers Nitric Oxide (NO) in Humans." In Cerebral Vasospasm: Neurovascular Events After Subarachnoid Hemorrhage. Springer Vienna, 2012. http://dx.doi.org/10.1007/978-3-7091-1192-5_11.

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Conference papers on the topic "Sodium humate"

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Zhu, Dongdong, Neng Guo, Xueyong Kou, Shuaipeng Li, Shengwen Chen, and Zhiguo Sun. "CO2 absorption by diethanolamine mixed with sodium humate." In Fifth International Conference on Green Energy, Environment, and Sustainable Development, edited by Mohammadreza Aghaei, Hongyu Ren, and Xiaoshuan Zhang. SPIE, 2024. http://dx.doi.org/10.1117/12.3044497.

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Mahapatra, Chitaranjan, Shuvendra Kumar Tripathy, Mrunmayee Tripathy, and Amritanshu Gupta. "A Computational Model of Voltage-Gated Sodium Ion Channel in Human Pulmonary Artery Smooth Muscle Cell." In 2025 International Conference on Cognitive Computing in Engineering, Communications, Sciences and Biomedical Health Informatics (IC3ECSBHI). IEEE, 2025. https://doi.org/10.1109/ic3ecsbhi63591.2025.10991320.

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Smuleac, Laura, Florin Imbrea, Adrian Smuleac, Raul Pascalau, and Radu Bertici. "THE INFLUENCE OF AGRICULTURAL ACTIVITIES ON THE QUALITY OF UNDERGROUND WATER IN THE CENTRAL AREA OF THE BANAT PLAIN UNDER THE CONDITIONS OF ADAPTATION TO CLIMATE CHANGE." In 24th SGEM International Multidisciplinary Scientific GeoConference 2024. STEF92 Technology, 2024. https://doi.org/10.5593/sgem2024v/3.2/s11.16.

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In the context of global climate change, groundwater is not only a vital source for human survival, but also a strategic resource for the sustainable development of local and global economies. The protection and effective management of these resources must be top priorities for everyone involved in environmental planning and management. The purpose of this work is to monitor the quality of groundwater from two water drillings located in the south of Timisoara and four water drillings in the west of the locality. The samples were taken in the year 2023 and were subjected to several analyzes (pH
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Jia, Shichao, Zhiguo Sun, Luhan Chen, Menglu Wang, and Run Feng. "Characteristics of CO2 Circulating Absorption by Sodium Humate and Potassium Carbonate." In 2019 2nd Asia Conference on Energy and Environment Engineering (ACEEE). IEEE, 2019. http://dx.doi.org/10.1109/aceee.2019.8817051.

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CHEN, JIANHUA, QIMING FENG, and LEMING OU. "THE FLOTATION SEPARATION OF CHALCOPYRITE-PYRITE IN THE PRESENCE OF SODIUM HUMATE." In Proceedings of the 4th International Conference. WORLD SCIENTIFIC, 2004. http://dx.doi.org/10.1142/9789812702623_0196.

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"Molecular composition - inhibition activity relationships for humic substances narrow fractions sets obtained by solid-phase extraction." In Sixth International Conference on Humic Innovative Technologies "Humic Substances and Eco-Adaptive Technologies ”(HIT – 2021). Non-Commercial Partnership "Center for Biogenic Resources "Humus Sapiens" (NP CBR "Humus Sapiens"), 2021. http://dx.doi.org/10.36291/hit.2021.mikhnevich.001.

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Humic substances (HS) have a wide spectrum of biological activity including inhibitory activity against β-lactamases.1 The latter are capable of hydrolyzing beta-lactam antibiotics and represent one of the main pathways of bacterial antibiotic resistance. HS are characterized by low toxicity and good solubility in water. A use of HS for therapeutic purposes is hindered by extreme molecular heterogeneity and high level of isomeric complexity. Solid-phase extraction (SPE) fractionation in combination with ultra-high resolution mass spectrometry (FTICR MS) is a promising method to simplify this m
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Ji, H., R. Zhao, D. Bhattarai, H. G. Nie, and G. Ali. "Plasmin Cleaves Human Epithelial Sodium Channels to Resolve Lung Edema." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1156.

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Sahin, Ali, and Murat Senturk. "The effect of sodium pertechnetate human carbonic anhydrase I and II." In II. INTERNATIONAL CONFERENCE ON ADVANCES IN NATURAL AND APPLIED SCIENCES: ICANAS 2017. Author(s), 2017. http://dx.doi.org/10.1063/1.4981758.

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Cheung, Nai Ho, and C. W. Ng. "Detection of sodium and potassium in single human red blood cells." In Biomedical Optical Spectroscopy and Diagnostics. OSA, 2000. http://dx.doi.org/10.1364/bosd.2000.suh1.

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Agyapong, Wilson, André Kleinridders, and Robert Hauffe. "Investigating the effect of sodium selenite treatment on human adipocyte homeostasis." In Diabetes Kongress 2023 - 57. Jahrestagung der DDG. Georg Thieme Verlag, 2023. http://dx.doi.org/10.1055/s-0043-1767881.

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Reports on the topic "Sodium humate"

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Gordon, Dalia, Ke Dong, and Michael Gurevitz. Unexpected Specificity of a Sea Anemone Small Toxin for Insect Na-channels and its Synergic Effects with Various Insecticidal Ligands: A New Model to Mimic. United States Department of Agriculture, 2010. http://dx.doi.org/10.32747/2010.7697114.bard.

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Motivated by the high risks to the environment and human health imposed by the current overuse of chemical insecticides we offer an alternative approach for the design of highly active insect-selective compounds that will be based on the ability of natural toxins to differentiate between insect and mammalian targets. We wish to unravel the interacting surfaces of insect selective toxins with their receptor sites on voltage-gated sodium channels. In this proposal we put forward two recent observations that may expedite the development of a new generation of insect killers that mimic the highly
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Krager, Kimberly J., and Frederick E. Domann. Genetically Targeted Radiotherapy Utilizing the Human Sodium Iodide Symporter in Human Breast Carcinoma Cells. Defense Technical Information Center, 2005. http://dx.doi.org/10.21236/ada436156.

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Krager, Kimberly, and Frederick E. Domann. Genetically Targeted Radiotherapy Utilizing the Human Sodium Iodide Symporter in Human Breast Carcinoma Cells. Defense Technical Information Center, 2006. http://dx.doi.org/10.21236/ada455269.

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Keltner, John Robinson. Triple-quantum filtered NMR imaging of sodium in the human brain. Office of Scientific and Technical Information (OSTI), 1993. http://dx.doi.org/10.2172/10184286.

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Rujiravanit, Ratana. Preparation and characterization of hydrogel from chitin derivative and silk fibroin. Thailand Research Fund, 2003. https://doi.org/10.58837/chula.res.2003.80.

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Natural polymer blend films composed of chitosan and silk fibroin were prepared by solution casting technique with various ratios of chitosan to silk fibroin, using glutaraldehyde as crosslinking agent. The effects of the ratio of chitosan to silk fibroin and crosslinking agent on mechanical properties, swelling behavior and drug releasing property of the blend films were studied. For the swelling behavior, the blend films exhibited a dramatic change in the degree of swelling when immersed in acidic solutions. The blend film with 80% chitosan content had the maximum degree of swelling. It appe
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Gaffin, S. L., M. S. Koratich, and R. W. Hubbard. The Effect of Hyperthermia on Intracellular Sodium Concentration in Isolated Human Cells. A Preliminary Report. Defense Technical Information Center, 1996. http://dx.doi.org/10.21236/ada331123.

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กาญจนบุษย์, เถลิงศักดิ์, กุลวรา เมฆสวรรค์, อังคณา ตันติธุวานนท์, วิภาวี กิตติโกวิท, พรทิพย์สวรรค์ นวลทอง та พรเพ็ญ พนมวัลย์. การพัฒนาและการศึกษาความเป็นไปได้ในการนำน้ำตาลเชิงซ้อน-แคลวิตินมาผลิตเป็นน้ำยาฟอกไตทางช่องท้องทดแทนน้ำยาฟอกไตมาตรฐาน. คณะแพทยศาสตร์ จุฬาลงกรณ์มหาวิทยาลัย, 2010. https://doi.org/10.58837/chula.res.2010.17.

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Background. The optimal formula of calvitrin based peritoneal dialysis was composing of calvitrin 6.25 g LL~:: electrolytes such as sodium chloride 540 g, sodium lactate 448 mg, calcium chloride 25.7mg and magnesium chloride 5.08 mg Methods. In vitro studies; the cytotoxicity was investigated. Human peritoneal mesothelial cells (HPMC) were isolated and characterized as described in tetail elsewhere (29). Cells were depleated serum and treated with 15% Cal-PD, 7.5% lcodextrin, 1.5% Dextose and media controls for 36 hrs. Cells morphology changes were examined under microscopy. The results found
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8

Gurevitz, Michael, William A. Catterall, and Dalia Gordon. face of interaction of anti-insect selective toxins with receptor site-3 on voltage-gated sodium channels as a platform for design of novel selective insecticides. United States Department of Agriculture, 2013. http://dx.doi.org/10.32747/2013.7699857.bard.

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Voltage-gated sodium channels (Navs) play a pivotal role in excitability and are a prime target of insecticides like pyrethroids. Yet, these insecticides are non-specific due to conservation of Navs in animals, raising risks to the environment and humans. Moreover, insecticide overuse leads to resistance buildup among insect pests, which increases misuse and risks. This sad reality demands novel, more selective, insect killers whose alternative use would avoid or reduce this pressure. As highly selective insect toxins exist in venomous animals, why not exploit this gift of nature and harness t
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Idowu, Olutosin R. Support of Study Entitled, Metabolism and Pharmacokinetics of Dihydroartemisinin" and "In Vitro and In Vivo Metabolism of Sodium Artelinate and DQHS in Rats and Humans".". Defense Technical Information Center, 1998. http://dx.doi.org/10.21236/ada368434.

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10

Gurevitz, Michael, William A. Catterall, and Dalia Gordon. Learning from Nature How to Design Anti-insect Selective Pesticides - Clarification of the Interacting Face between Insecticidal Toxins and their Na-channel Receptors. United States Department of Agriculture, 2010. http://dx.doi.org/10.32747/2010.7697101.bard.

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Structural details on the interacting faces of toxins and sodium channels (Navs), and particularly identification of elements that confer specificity for insects, are difficult to approach and require suitable experimental systems. Therefore, natural toxins capable of differential recognition of insect and mammalian Navs are valuable leads for design of selective compounds in insect control. We have characterized several scorpion toxins that vary in preference for insect and mammalian Navs, and identified residues important for their action. However, despite many efforts worldwide, only little
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