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Journal articles on the topic 'Sodium hyaluronate gel'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Orlenko, Dmytro, Volodymyr Yakovenko, Vyacheslav Plastun, and Liliia Vyshnevska. "DEVELOPMENT AND VALIDATION OF METHODS FOR QUANTITATIVE DETERMINATION OF SODIUM HYALURONATE IN THE COMPOSITION OF COMBINED DENTAL GEL." EUREKA: Health Sciences 5 (September 30, 2020): 72–81. http://dx.doi.org/10.21303/2504-5679.2020.001420.

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According to the EP monograph "Sodium hyaluronate" for identification they use the infrared transmission spectrum of the substance, quantification is carried out by spectrophotometry. The aim of the work was to develop a method for quantitative determination of hyaluronic acid in the gel in the presence of other substances and its validation. Materials and Methods. The object of the study were samples of combined dental gel of the following composition: metronidazole benzoate 16 mg/g, miramistin 5 mg / g, sodium hyaluronate 2 mg / g. Identification and quantification of sodium hyaluronate was

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Dmytro, Orlenko, Yakovenko Volodymyr, Plastun Vyacheslav, and Vyshnevska Liliia. "DEVELOPMENT AND VALIDATION OF METHODS FOR QUANTITATIVE DETERMINATION OF SODIUM HYALURONATE IN THE COMPOSITION OF COMBINED DENTAL GEL." EUREKA: Health Sciences, no. 5 (September 30, 2020): 72–81. https://doi.org/10.21303/2504-5679.2020.001420.

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According to the EP monograph "Sodium hyaluronate" for identification they use the infrared transmission spectrum of the substance, quantification is carried out by spectrophotometry. <strong>The aim</strong> of the work was to develop a method for quantitative determination of hyaluronic acid in the gel in the presence of other substances and its validation. <strong>Materials and Methods. </strong>The object of the study were samples of combined dental gel of the following composition: metronidazole benzoate 16 mg/g, miramistin 5 mg / g, sodium hyaluronate 2 mg / g. Identi

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3

Zhang, Jun, Hanyan Mao, Xi Zou, and Guohua Deng. "Use of medical sodium hyaluronate gel in surgical removal of a glass intraocular foreign body." Journal of International Medical Research 48, no. 9 (2020): 030006052095685. http://dx.doi.org/10.1177/0300060520956856.

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A 38-year-old healthy man presented to our department of ophthalmology after sustaining an ocular injury in a glass explosion more than 10 days prior. A glass intraocular foreign body (IOFB) was found in the left eye. During surgical removal of the IOFB, medical sodium hyaluronate gel was used to detach the IOFB from the retina; this avoided damage to the retina and made it easier for the surgeons to grasp the glass fragment. Multiple surgical instruments have been developed to help remove IOFBs; however, many optic hospitals have limited surgical instruments, thus increasing the difficulty of

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Duman, Gülengül, İsmail Aslan, A. Yekta Özer, İbrahim İnanç, and Alpay Taralp. "Liposome, gel and lipogelosome formulations containing sodium hyaluronate." Journal of Liposome Research 24, no. 4 (2014): 259–69. http://dx.doi.org/10.3109/08982104.2014.907305.

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Zhao, Yong Liang, Tian Tian Meng, Wei Guo Wang, and Jia Li Wan. "Determination of Free Polyethylene Glycol in Cross-Linked Sodium Hyaluronate Gel." Advanced Materials Research 881-883 (January 2014): 918–22. http://dx.doi.org/10.4028/www.scientific.net/amr.881-883.918.

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Abstract: In this study we present a method for the determination of free polyethylene glycol in a gel. We detect the PEG residues of cross-linked sodium hyaluronate gel by spectrophotometry. The pretreatment of cross-linked sodium hyaluronate gel is special and the plot of working curve is unconventional. The precision, the recovery rate with marker, the reliability and repeatability of this method are tested and verified. The results indicated that the method has an excellent linear relationship in the range of 0-40.5µg mL-1. The regression equation is Y=0.0108X+0.2047 (R2=0.9994). The stand

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Yamagishi, Rio, Sayaka Miura, Kana Yabu, et al. "Fabrication Technology of Self-Dissolving Sodium Hyaluronate Gels Ultrafine Microneedles for Medical Applications with UV-Curing Gas-Permeable Mold." Gels 10, no. 1 (2024): 65. http://dx.doi.org/10.3390/gels10010065.

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Microneedles are of great interest in diverse fields, including cosmetics, drug delivery systems, chromatography, and biological sensing for disease diagnosis. Self-dissolving ultrafine microneedles of pure sodium hyaluronate hydrogels were fabricated using a UV-curing TiO2-SiO2 gas-permeable mold polymerized by sol-gel hydrolysis reactions in nanoimprint lithography processes under refrigeration at 5 °C, where thermal decomposition of microneedle components can be avoided. The moldability, strength, and dissolution behavior of sodium hyaluronate hydrogels with different molecular weights were

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Kvashnina, A. A., M. G. Melnychenko, and V. F. Rybalchenko. "Clinical effectiveness of sodium hyaluronate gel usage for prevention of postoperative adhesion in children." Modern pediatrics. Ukraine, no. 2(122) (March 30, 2022): 21–26. http://dx.doi.org/10.15574/sp.2022.122.21.

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It was considered expedient to study the effectiveness of intraoperative prevention of adhesion formation in children based on the results of our own experimental and clinical studies on the effectiveness of using an anti-adhesive gel based on cross-linked sodium hyaluronate. Purpose - to evaluate clinical efficacy and safety of cross-linked sodium hyaluronate gel (SHG) usage as a barrier agent for primary prevention of postoperative peritoneal adhesions formation in children. Materials and methods. This is a prospective, randomized, controlled, patient blinded observational study, which inclu

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Morris, Elisabeth A., Sandra Wilcon, and Benjamin V. Treadwell. "Inhibition of interleukin 1-mediated proteoglycan degradation in bovine articular cartilage explants by addition of sodium hyaluronate." American Journal of Veterinary Research 53, no. 11 (1992): 1977–82. http://dx.doi.org/10.2460/ajvr.1992.53.11.1977.

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Summary The effect of exogenous hyaluronate on normal cartilage metabolism and interleukin-1 (il-1)-induced cartilage matrix degradation was investigated in a bovine cartilage explant culture system. Addition of hyaluronate at a concentration of 1.5 mg/ml to cartilage culture explants consistently decreased normal proteoglycan release from the matrix to a value less than that found in control cultures. Addition of 1.5 mg of hyaluronate/ml to il-1 stimulated cartilage culture systems reduced proteoglycan release from the matrix by 83 to 113%. The reduction in control and il-1-stimulated proteog

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9

Dmytro, Orlenko, Yakovenko Volodymyr, and Vyshnevska Liliia. "Research on the development of dental gel technology with metronidazole benzoate and hyaluronic acid." ScienceRise: Pharmaceutical Science, no. 6(22) (December 30, 2019): 24–29. https://doi.org/10.15587/2519-4852.2019.189949.

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<strong>Methods. </strong>After production of experimental gel, we determined homogeneity for the samples with the method of SPhU 1.1, section 511. The particle size of the suspension was studied using a XY-B2TLED microscope under polarized light according to SPhU 2.9.37. The quantitative determination of metronidazole benzoate and the accompanying impurities A, B, C, miramistin, sodium hyaluronate was performed by liquid chromatography, according to SPhU section 2.2.29, section 2.2.46. <strong>Results. </strong>According to the results of chemical and microscopic studies, the optima

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10

Wu, Hairui, Yingfeng Shao, Wei Li, Yu Zhao, and Fan Song. "A new method for characterization of the cohesion of sodium hyaluronate gel." Journal of Physics: Conference Series 2964, no. 1 (2025): 012091. https://doi.org/10.1088/1742-6596/2964/1/012091.

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Abstract Cohesion refers to the ability of the material not to separate, and the evaluation of cohesion for hyaluronic-based tissue fillers is conducive to their clinical application. In this paper, a characterization method based on gel microcolumn stretching is developed for the cohesion of hyaluronic acid-based fillers. The method has clear physical significance and can be used to measure the true stress-strain relationship of soft gel fillers. We use this method to measure the cohesion of four hyaluronic acid-based fillers and evaluate the cohesion of the same products using the method bas

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Senthil, Venkatachalam, V. Harsha Merikanapalli, Pooja M., Paranjothy Murali, and Rajesh Kumar R. "Enhanced Bio-Adhesion and Sustained Delivery of Clotrimazole Encapsulated Solid Lipid Nanoparticles Loaded in Hyaluronic Acid Gel as Anti- Fungal Therapy." British Journal of Pharmaceutical Research 17, no. 1 (2017): 1–12. https://doi.org/10.9734/BJPR/2017/34063.

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<strong>Aim: </strong>Clotrimazole (CTZ) is a broad spectrum anti-fungal drug which faces inability to retain over skin for longer duration and faces systemic side effects. The rationale behind present research effort was to attain sustained release of drug by lipid nanocarriers, enhance absorption by prolonged retention of gel and improve the patient compliance by reducing the dosing frequency. <strong>Study Design: </strong>CTZ solid lipid nanoparticles (SLN) were prepared by solvent emulsification method and loaded into sodium hyaluronate (Na-Hy) gel. <strong>Methodology:</strong> CTZ-SLN w

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Wang, Hao, Dong Zhou, Zhuo Sun, Shanshan Sun, and Guohua Deng. "Effects of Calf Blood-Deproteinized Extract Ophthalmic Gel Combined with Sodium Hyaluronate Eye Drops on Conjunctival Hyperemia Score and Tear Film Stability in Patients with Dry Eye." Computational Intelligence and Neuroscience 2022 (June 3, 2022): 1–7. http://dx.doi.org/10.1155/2022/6732914.

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Objective. The aim of this paper is to research the impact of calf blood-deproteinized extract ophthalmic gel combined with sodium hyaluronate eye drops on conjunctival hyperemia score and tear film stability in patients having dry eye. Methods. 144 patients having dry eye disease who were hospitalized from July 2018 to July 2021 were chosen as the research targets, which were composed of the control group and research group on the basis of the sequences of hospitalization, and each has 72 cases. The sodium hyaluronate eye drops were gained in the control one. In accordance with the control on

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Wang, Chunyu, Yangli Zhang, Hailong Yang, et al. "Platelet lysate-sodium hyaluronate gel promotes diabetic foot wound healing by regulating oxidative stress and autophagy." PLOS One 20, no. 6 (2025): e0324264. https://doi.org/10.1371/journal.pone.0324264.

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Diabetic foot ulcer (DFU) is a major complication of diabetes which is difficult to heal and has high recurrence rates. It often requires amputation and even causes death, imposing significant economic burden on the society. Moreover, the current treatment options are not sufficiently effective, necessitating the search for novel treatments. In this study, therapeutic effect and mechanisms of platelet lysate-sodium hyaluronate gel (PL-HA gel) in the treatment of DFU were studied. Initially, the PL-HA gel was examined for quality control, and then the expression of growth factors (GFs) content

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14

Lee, Kwang Beom, Seung Joo Chon, Sunghoon Kim, et al. "Using Type I Collagen Gel to Prevent Postoperative Intrauterine Adhesion: A Multicenter Retrospective Study." Journal of Clinical Medicine 12, no. 11 (2023): 3764. http://dx.doi.org/10.3390/jcm12113764.

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We evaluated the clinical outcomes of using type 1 collagen gel after therapeutic resectoscopy; overall, 150 women aged > 20 who planned to undergo therapeutic resectoscopy were enrolled. The patients were randomly assigned to either of the anti-adhesive treatment groups: the type 1 collagen gel (Collabarrier®) (study group; N = 75) or the sodium hyaluronate and sodium carboxymethylcellulose gel group (control group; N = 75) after resectoscopy. One month after applying anti-adhesive materials, postoperative intrauterine adhesions were evaluated using second-look hysteroscopy; the incidence

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Hakim, Rachmi Fanani, Fakhrurrazi Fakhrurrazi, and Fatimah Sahara Zamzami. "Comparison of the effect of guava (psidium guajava l.) Leaf extract x withpolyvinylpyrrolidone-sodium hyaluronate on the number fibroblasts (study on white rats [rattus norvegicus])." Odonto : Dental Journal 10, no. 1 (2023): 61. http://dx.doi.org/10.30659/odj.10.1.61-68.

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Background: Wound healing is a cellular and complex process that aims to restore the integrity of tissue damaged by injury. The phases that occur in the wound healing process are inflammation, proliferation, and maturation (remodeling). One of the final results of wound healing is fibroblasts proliferation. Fibroblasts have the ability to synthesize collagen fibeBackground: Wound healing is a cellular and complex process that aims to restore the integrity of tissue damaged by injury. The phases that occur in the wound healing process are inflammation, proliferation, and maturation (remodeling)

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Shostak, Michail S., Iana A. Leineman, Evgeniy A. Trofimov, and Vadim I. Mazurov. "Treatment of patients with knee osteoarthritis with hyaluronate sodium (Revisk) in clinical practice." HERALD of North-Western State Medical University named after I.I. Mechnikov 15, no. 1 (2023): 107–15. http://dx.doi.org/10.17816/mechnikov229980.

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BACKGROUND: Osteoarthritis is a disease highly associated with a wide range of comorbidities, which leads to significant limitations of the therapeutic possibilities, in particular, the long-term use of non-steroidal anti-inflammatory drugs. Thus, develop algorithms for effective treatment of osteoarthritis aimed at reducing the need for anti-inflammatory therapy is of great importance. AIM: To evaluate the efficacy and safety of hyaluronic acid for the treatment of osteoarthritis in patients with comorbid pathology. MATERIALS AND METHODS: 30 patients aged 40 to 65 years with IIIII

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17

Yamagishi, Rio, Sayaka Miura, Kaori Yasuda, et al. "Thermal nanoimprint lithography of sodium hyaluronate solutions with gas permeable inorganic hybrid mold for cosmetic and pharmaceutical applications." Applied Physics Express 15, no. 4 (2022): 046502. http://dx.doi.org/10.35848/1882-0786/ac5ba6.

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Abstract Gas-permeable inorganic hybrid mold that hybridized the surface layer of TiO2–SiO2 gas-permeable polymer using the sol–gel method and the lower layer of porous maraging steel by a metal three-dimensional printer was developed for fluid function materials containing high concentrations of water and volatile solvents. Thermal nanoimprint lithography was used to fabricate the advanced high-resolution needle patterning of sodium hyaluronate containing volatile solvents to broaden the application area of fluid function materials such as cosmetics and pharmaceuticals.

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Chen, Ran, Fanglin Du, and Qipeng Yuan. "Multifunctional Sodium Hyaluronate/Chitosan Foam Used as an Absorbable Hemostatic Material." Bioengineering 10, no. 7 (2023): 868. http://dx.doi.org/10.3390/bioengineering10070868.

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Absorbable hemostatic materials have great potential in clinical hemostasis. However, their single coagulation mechanism, long degradation cycles, and limited functionality mean that they have restricted applications. Here, we prepared a sodium hyaluronate/carboxymethyl chitosan absorbable hemostatic foam (SHCF) by combining high-molecular-weight polysaccharide sodium hyaluronate with carboxymethyl chitosan via hydrogen bonding. SHCFs have rapid liquid absorption performance and can enrich blood cells. They transform into a gel when it they come into contact with blood, and are more easily deg

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Gaughan, Earl M., Alan J. Nixon, Lennart P. Krook, et al. "Effects of sodium hyaluronate on tendon healing and adhesion formation in horses." American Journal of Veterinary Research 52, no. 5 (1991): 764–73. http://dx.doi.org/10.2460/ajvr.1991.52.05.764.

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SUMMARY Sodium hyaluronate reduces adhesions after tendon repair in rodents and dogs, and has been used in limited clinical trials in people. To evaluate its effect on tendon healing and adhesion formation in horses and to compare these effects with those of a compound of similar viscoelastic properties, a study was performed in horses, using a model of collagenase injection in the flexor tendons within the digital sheath. Eight clinically normal horses were randomly allotted to 2 groups. Adhesion formation between the deep digital flexor tendon and the tendon sheath at the pastern region was

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Lee, Kwang-Il, Tae-Hoon Koo, Peter Chen, and Darryl D. D’Lima. "Subcutaneous toxicity of a dual ionically cross-linked atelocollagen and sodium hyaluronate gel." Toxicology Reports 8 (2021): 1651–56. http://dx.doi.org/10.1016/j.toxrep.2021.09.001.

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21

Mettler, Liselotte, Wael Sammur, Thoralf Schollmeyer, and Ibrahim Alkatout. "Cross-linked sodium hyaluronate, an anti-adhesion barrier gel in gynaecological endoscopic surgery." Minimally Invasive Therapy & Allied Technologies 22, no. 5 (2013): 260–65. http://dx.doi.org/10.3109/13645706.2012.751034.

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Montalvo-Javé, Eduardo Esteban, German Eduardo Mendoza-Barrera, Manuel Alejandro García-Pineda, et al. "Histological Analysis of Intra-Abdominal Adhesions Treated with Sodium Hyaluronate and Carboxymethylcellulose Gel." Journal of Investigative Surgery 29, no. 2 (2015): 80–87. http://dx.doi.org/10.3109/08941939.2015.1076911.

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Yanchenko, S. V., A. V. Malyshev, and S. N. Sakhnov. "The Choice of Dry Eye Therapy Depending on Ocular Surface Condition." Ophthalmology in Russia 18, no. 2 (2021): 346–54. http://dx.doi.org/10.18008/1816-5095-2021-2-346-354.

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Purpose: to develop approaches to differentiated substitution therapy in patients with dry eye (DE) of mild and moderate severity.Patients and methods. We examined 86 DE patients (22–45 years old; 38 men, 48 women). Group-1 included 54 patients (54 eyes) with mild DE under conditions of combined lipid-mucose-deficiency, group-2 32 patients (32 eyes) with moderate DE against the background of combined lipid-aqua-mucose-deficiency. Conducted: DE symptoms registration (OSDI scale); Norn and Shirmer-1 tests; OCT meniscometry; assessment of the Bijsterveld xerosis index and ‘lid-vipers’ symptom ide

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Mo, Yunqian, Kenji Kubota, and Katusyoshi Nishinari. "Rheological evidence of the gelation behavior of hyaluronan–gellan mixtures." Biorheology: The Official Journal of the International Society of Biorheology 37, no. 5-6 (2000): 401–8. http://dx.doi.org/10.1177/0006355x2000037005006001.

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It was found that solutions of calcium hyaluronate (CaHA) (0.1∼0.5 wt%) could form a gel by mixing with solutions of sodium type gellan (0.1∼0.5 wt%), although neither polymer by itself forms a gel at low concentrations (0.1∼0.5 wt% in this experiment). The rheological properties of CaHA–gellan mixtures were investigated by dynamic and steady shear measurements. Both storage shear modulus G′ and loss shear modulus G″ for CaHA–gellan mixtures increased with increasing time, and tended to an equilibrium value after 1 h. After reaching steady values of G′ and G″, the frequency dependence of G′ an

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Cui, Yu Jia, Wei Guo Wang, Peng Li, Yong Liang Zhao, Ya Nan Gu, and Jia Li Wan. "The Comparison of Physicochemical Properties of Four Cross-Linked Sodium Hyaluronate Gels with Different Cross-Linking Agents." Advanced Materials Research 396-398 (November 2011): 1506–12. http://dx.doi.org/10.4028/www.scientific.net/amr.396-398.1506.

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Abstract：PurposeThe physicochemical properties of four Cross-linked sodium hyaluronate gels(CHA) with different cross-linking agents were conpared.In order to research out the different stability and Enzyme-resistant properties of these CHA.Methods The CHA hydrogels were prepared with different cross-linking agents, such as PEG20000, PDE, BDDE and ADH. The optimal reaction conditions were determined by single factor experiment. Dynamic viscosity was tested by Stabinger method. Intrinsic viscosity was tested by Uzziah's viscosity method. The in vitro Enzyme-resistant properties of CHA-gels were

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Sakhnov, S. N., S. V. Yanchenko, A. V. Malyshev, et al. "Effectiveness and safety of demodecosis blepharitis therapy under dry eye conditions." Russian Ophthalmological Journal 17, no. 2 (2024): 32–37. http://dx.doi.org/10.21516/2072-0076-2024-17-2-32-37.

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Purpose: to evaluate the effectiveness and safety of complex therapy in patients with demodex blepharitis and dry eye. Methods. 25 patients with mixed demodex blepharitis and dry eye (50 eyes; 10 men, 15 women; 61.9 ± 5.6 years) were examined before and after treatment with 0.5 % levofloxacin instillation (5 times a day, 5 days); sulfur and metronidazole gel applications (Blefarogel-forte) as part of therapeutic eyelid hygiene (Blepharogel-cleansing, Blepharolotion; starting from day 6, 2 times a day, 45 days); 0.24 % sodium hyaluronate instillation (3 times a day). Therapy effectiveness crite

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Wei, Guangbing, Cancan Zhou, Guanghui Wang, Lin Fan, Kang Wang, and Xuqi Li. "Keratinocyte Growth Factor Combined with a Sodium Hyaluronate Gel Inhibits Postoperative Intra-Abdominal Adhesions." International Journal of Molecular Sciences 17, no. 10 (2016): 1611. http://dx.doi.org/10.3390/ijms17101611.

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Chabreček, P., L. Šoltés, Z. Kállay, and I. Novák. "Gel permeation chromatographic characterization of sodium hyaluronate and its fractions prepared by ultrasonic degradation." Chromatographia 30, no. 3-4 (1990): 201–4. http://dx.doi.org/10.1007/bf02274547.

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Jun, Li, Wang Jing, and Alvin L. Young. "Sodium Hyaluronate Gel as Mitomycin C Vehicle to Reduce Potential Endothelial Toxicity in Pterygium Surgery." Cornea 30, no. 11 (2011): 1286–87. http://dx.doi.org/10.1097/ico.0b013e31820ce270.

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Liu, Hua, Hai-Feng Li, and Jian-Yuan Wang. "Prevention effect of medical self-crosslinking sodium hyaluronate gel on epidural scar adhesion after laminectomy." Asian Pacific Journal of Tropical Medicine 7, no. 6 (2014): 501–4. http://dx.doi.org/10.1016/s1995-7645(14)60083-3.

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Uhart, M., F. Pirot, A. Boillon, et al. "Assessment of sodium hyaluronate gel as vehicle for intracameral delivery of cefuroxime in endophthalmitis prophylaxis." International Journal of Pharmaceutics 398, no. 1-2 (2010): 14–20. http://dx.doi.org/10.1016/j.ijpharm.2010.07.009.

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Wang, Wei Guo, Yu Jia Cui, Peng Li, Yong Liang Zhao, Ya Nan Gu, and Jia Li Wan. "Preparation of Cross-Linked Sodium Hyaluronate Gels with Different Molecular Weights of PEG and Research for its Viscoelasticity and Enzyme-Resistant Properties In Vitro." Advanced Materials Research 399-401 (November 2011): 1552–58. http://dx.doi.org/10.4028/www.scientific.net/amr.399-401.1552.

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Abstract: Purpose To screen out the optimal conditions of cross-linking reaction of preparing for an injectable cross-linked sodium hyaluronate gel(CHA-gel) with higher resistance to hyaluronidase and research for its viscoelasticity and anti-enzyme degradation properties. Methods The CHA hydrogels were prepared with different molecular weights of PEG as cross-linking agent, such as PEG400, PEG1000, PEG6000, PEG10000, PEG20000. The optimal preparing conditions were determined by single factor test and orthogonal experiment. The Enzyme-resistant degradation properties in vitro of CHA-gels were

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Molotkov, A. S., E. N. Popov, A. O. Ivanova, and E. V. Kazantseva. "Experience of the use of anti-adhesive barrier based on sodium hyaluronate and carboxymethylcellulose in gynecological surgery." Medical Council, no. 13 (October 10, 2019): 149–53. http://dx.doi.org/10.21518/2079-701x-2019-13-149-153.

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The article presents our experience in the use of anti-adhesive barrier based on hyaluronic acid and carboxymethylcellulose in gynecological surgery. The study included 63 patients who underwent removal of polyps, uterine fibroids, intrauterine synechiae, removal of ovarian cysts. At the end of operations an anti-adhesive gel was introduced into the uterine cavity and into the abdominal cavity to prevent adhesions. Efficacy and safety were assessed in the early postoperative period and with a further sixmonth follow-up of patients. It is noted that the introduction of the gel does not lead to

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Scomoroscenco, Cristina, Mircea Teodorescu, Adina Raducan, et al. "Novel Gel Microemulsion as Topical Drug Delivery System for Curcumin in Dermatocosmetics." Pharmaceutics 13, no. 4 (2021): 505. http://dx.doi.org/10.3390/pharmaceutics13040505.

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Gel microemulsion combines the advantages of the microemulsion, which can encapsulate, protect and deliver large quantities of active ingredients, and the gel, which is so appreciated in the cosmetic industry. This study aimed to develop and characterize new gel microemulsions suitable for topical cosmetic applications, using grape seed oil as the oily phase, which is often employed in pharmaceuticals, especially in cosmetics. The optimized microemulsion was formulated using Tween 80 and Plurol® Diisostearique CG as a surfactant mix and ethanol as a co-solvent. Three different water-soluble po

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Wang, Chunlei, Qiuping Fan, Xiaofei Zhang, et al. "Isolation, Characterization, and Pharmaceutical Applications of an Exopolysaccharide from Aerococcus Uriaeequi." Marine Drugs 16, no. 9 (2018): 337. http://dx.doi.org/10.3390/md16090337.

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Many marine bacteria secrete exopolysaccharides (EPSs), which are made up of a substantial component of the macro-molecules surrounding cells. Recently, the wide demand for EPSs for food, cosmetics, pharmaceutical and other applications has led to great interest in them. In this study, an EPS produced by marine bacteria Aerococcus uriaeequi HZ strains (EPS-A) was isolated and purified to examine its structure and biological function. The molecular weight of EPS-A analyzed by high-performance liquid gel filtration chromatography (HPGFC) is found to have a number average of 2.22 × 105 and weight

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Scomoroscenco, Cristina, Mircea Teodorescu, Cristina Lavinia Nistor, et al. "Preparation and In Vitro Characterization of Alkyl Polyglucoside-Based Microemulsion for Topical Administration of Curcumin." Pharmaceutics 15, no. 5 (2023): 1420. http://dx.doi.org/10.3390/pharmaceutics15051420.

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The skin is a complex and selective system from the perspective of permeability to substances from the external environment. Microemulsion systems have demonstrated a high performance in encapsulating, protecting and transporting active substances through the skin. Due to the low viscosity of microemulsion systems and the importance of a texture that is easy to apply in the cosmetic and pharmaceutical fields, gel microemulsions are increasingly gaining more interest. The aim of this study was to develop new microemulsion systems for topical use; to identify a suitable water-soluble polymer in

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CAI, Tongkai, Hua HAN, Yongbing CAO, and Lan YAN. "Anti-adhesive effect of medical sodium hyaluronate gel and its effect on wound healing and antibiotics." Pharmaceutical Care and Research 20, no. 2 (2020): 92–97. http://dx.doi.org/10.5428/pcar20200203.

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Wang, Xiao, Wan-Wei Dai, Ya-Long Dang, Ying Hong та Chun Zhang. "Five Yearsʼ Outcomes of Trabeculectomy with Cross-linked Sodium Hyaluronate Gel Implantation for Chinese Glaucoma Patients". Chinese Medical Journal 131, № 13 (2018): 1562–68. http://dx.doi.org/10.4103/0366-6999.233655.

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Saber, Amanj, Göran Laurell, Tobias Bramer, Katarina Edsman, Cecilia Engmér, and Mats Ulfendahl. "Middle Ear Application of a Sodium Hyaluronate Gel Loaded with Neomycin in a Guinea Pig Model." Ear and Hearing 30, no. 1 (2009): 81–89. http://dx.doi.org/10.1097/aud.0b013e31818ff98e.

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Tanikaze, Saburo, Yuichi Osa, Minoru Tada, et al. "DEXTRANOMER BEADS IN STABILIZED NON-ANIMAL SODIUM HYALURONATE GEL (NASHA/Dx GEL) FOR VESICOURETERAL REFLUX: MULTI-CENTER STUDY IN JAPANEASE PATIENTS." Japanese Journal of Urology 101, no. 5 (2010): 676–82. http://dx.doi.org/10.5980/jpnjurol.101.676.

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Buchsel, Patricia C., and Patrick JM Murphy. "Polyvinylpyrrolidone–sodium hyaluronate gel (Gelclair®): a bioadherent oral gel for the treatment of oral mucositis and other painful oral lesions." Expert Opinion on Drug Metabolism & Toxicology 4, no. 11 (2008): 1449–54. http://dx.doi.org/10.1517/17425255.4.11.1449.

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Joukhadar, Radwan, Laura Nižić Nodilo, Jasmina Lovrić, Anita Hafner, Ivan Pepić, and Mario Jug. "Functional Nanostructured Lipid Carrier-Enriched Hydrogels Tailored to Repair Damaged Epidermal Barrier." Gels 10, no. 7 (2024): 466. http://dx.doi.org/10.3390/gels10070466.

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In this study, a functional nanostructured lipid carriers (NLCs)-based hydrogel was developed to repair the damaged epidermal skin barrier. NLCs were prepared via a high-energy approach, using argan oil and beeswax as liquid and solid lipids, respectively, and were loaded with ceramides and cholesterol at a physiologically relevant ratio, acting as structural and functional compounds. Employing a series of surfactants and optimizing the preparation conditions, NLCs of 215.5 ± 0.9 nm in size and a negative zeta potential of −42.7 ± 0.9 were obtained, showing acceptable physical and microbial st

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Fondi, Klemens, Piotr A. Wozniak, Doreen Schmidl, et al. "Effect of Hyaluronic Acid/Trehalose in Two Different Formulations on Signs and Symptoms in Patients with Moderate to Severe Dry Eye Disease." Journal of Ophthalmology 2018 (August 1, 2018): 1–7. http://dx.doi.org/10.1155/2018/4691417.

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Purpose. This randomized, observer-masked, crossover study investigated the effect of two hyaluronic acid/trehalose-based containing formulations, with different physical properties, on the signs and symptoms in patients with moderate to severe dry eye disease (DED). Methods. In one group, patients received a mixture of sodium hyaluronate and trehalose (HT, Thealoz Duo®) for use during the day. In the other group, patients received a more viscous formulation consisting of hyaluronic acid, trehalose, and carbomer (HTC-gel, Thealoz Duo Gel) to use pro re nata. Both groups used HTC-gel before goi

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Hu, Jiancong, Dejun Fan, Xutao Lin, et al. "Safety and Efficacy of Sodium Hyaluronate Gel and Chitosan in Preventing Postoperative Peristomal Adhesions After Defunctioning Enterostomy." Medicine 94, no. 51 (2015): e2354. http://dx.doi.org/10.1097/md.0000000000002354.

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Beaty, Narlin B., William P. Tew, and Robert J. Mello. "Relative molecular weight and concentration determination of sodium hyaluronate solutions by gel-exclusion high-performance liquid chromatography." Analytical Biochemistry 147, no. 2 (1985): 387–95. http://dx.doi.org/10.1016/0003-2697(85)90287-8.

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Capodiferro, Saverio, Angela Tempesta, Sabina Bucci, Eugenio Maiorano, Gianfranco Favia, and Luisa Limongelli. "Aminogam® Gel Allows Faster Wound Healing after Oral Surgery by Formation of Mature Connective Tissue with Low Vascular Density and Reducing Inflammatory Infiltration. A Retrospective Study on 580 Cases with Histological and Confocal Laser Investigation." Applied Sciences 10, no. 3 (2020): 1105. http://dx.doi.org/10.3390/app10031105.

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Reduction of the wound healing time after surgical procedures along with good hemostasis, and the reduction of post-surgical edema, pain and infective complications are generally desirable to both clinicians and patients. Recently, a gel compound containing sodium hyaluronate and four synthetic aminoacids (glycine, leucine, proline, lysine) and marketed as Aminogam® (Errekappa Euroterapici, Italy), has been proposed as a medical device promoting faster wound healing after oral surgery procedures. To assess its achievable clinical benefits, we studied retrospectively 580 cases (290 study cases

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Fitisheva, Larisa E., Vadim G. Mozes, Igor S. Zaharov, and Kira B. Mozes. "The effectiveness of anti-adhesive barrier based on carboxymethylcellulose 5 mg and sodium hyaluronate 2.5 mg in various methods of surgical treatment of ectopic tubal pregnancy." Gynecology 21, no. 2 (2019): 71–75. http://dx.doi.org/10.26442/20795696.2019.2.190360.

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Aim. To evaluate the effectiveness of the anti-adhesive barrier in the form of a gel based on carboxymethylcellulose 5 mg and sodium hyaluronate 2.5 mg with various techniques of surgical treatment of ectopic tubal pregnancy. Materials and methods. A randomized study was conducted on 98 women who underwent laparoscopic resection of the ampulla of the fallopian tube, together with a embryo, followed by neostomatoplasty or salpingostomy with or without an anti-adhesive barrier. The primary outcome of the study was the incidence of uterine pregnancy and its outcomes at 18 months of follow-up; sec

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Wójcik-Pastuszka, Dorota, Karolina Stawicka, Andrzej Dryś, and Witold Musiał. "Influence of HA on Release Process of Anionic and Cationic API Incorporated into Hydrophilic Gel." International Journal of Molecular Sciences 24, no. 6 (2023): 5606. http://dx.doi.org/10.3390/ijms24065606.

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The properties of sodium hyaluronate (HA), such as hygroscopicity, flexibility, the ability to form hydrogels, as well as biocompatibility and biodegradability, are beneficial for the applications in pharmaceutical technology, cosmetics industry, and aesthetic medicine. The aim of this study was to prepare HA-based hydrogels doped with active pharmaceutical ingredient (API): a cationic drug—lidocaine hydrochloride or anionic drug—sodium. The interaction between the carrier and the implemented active pharmaceutical substances was evaluated in prepared systems by applying viscometric measurement

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Bang, Sumi, Dipankar Das, Jiyun Yu, and Insup Noh. "Evaluation of MC3T3 Cells Proliferation and Drug Release Study from Sodium Hyaluronate-1,4-butanediol Diglycidyl Ether Patterned Gel." Nanomaterials 7, no. 10 (2017): 328. http://dx.doi.org/10.3390/nano7100328.

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Gulnazarova, Stella, Tatyana Isakova, and Aleksey Sverdlov. "Prospective comparative study of the use prp and viscoelastic sodium hyaluronate gel in patients with grade ii knee osteoarthritis." ORTHOPAEDICS, TRAUMATOLOGY and PROSTHETICS, no. 3 (October 4, 2019): 22–27. http://dx.doi.org/10.15674/0030-59872019322-27.

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