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Journal articles on the topic 'Solasodine'

Author: Grafiati
Published: 4 June 2021
Last updated: 26 July 2025

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1

Mokgehle, Tebogo Mphatlalala, Ntakadzeni Edwin Madala, and Nikita Tawanda Tavengwa. "Evaluation of a Chaotrope and Kosmotrope in the Multivariate Optimization of PHW-ATPE of Solasodine from Leaves of Solanum mauritianum." Molecules 27, no. 17 (2022): 5547. http://dx.doi.org/10.3390/molecules27175547.

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A hyphenated pressurized hot water—aqueous two-phase extraction (PHW-ATPE) method was applied to extract solasodine from Solanum mauritianum (S. mauritianum). A central composite design (CCD) was applied to determine the optimal conditions for the extraction of solasodine. The parameters evaluated included the percentage concentration of salt (NaCl or Na2CO3) and temperature. The fit of the central composite design response surface model for PHW-ATPE to the data generated a model with a good quadratic fit (R2 = 0.901). The statistically significant (p < 0.05) parameters, such as the linear
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2

Sarkar, Jeeta, and Nirmalya Banerjee. "Cytokinin Mediated Increased In Vitro Production of Secondary Metabolites with Special Reference to Solasodine in Solanum erianthum." Planta Medica International Open 8, no. 02 (2021): e62-e68. http://dx.doi.org/10.1055/a-1484-9750.

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AbstractSteroid alkaloid solasodine is a nitrogen analogue of diosgenin and has great importance in the production of steroidal medicines. Solanum erianthum D. Don (Solanaceae) is a good source of solasodine. The aim of this study was to evaluate the effect of different cytokinins on the production of secondary metabolites, especially solasodine in the in vitro culture of S. erianthum. For solasodine estimation, field-grown plant parts and in vitro tissues were extracted thrice and subjected to high-performance liquid Chromatography. Quantitative analysis of different secondary metabolites sho
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3

Deshmukh, V., J. Deshpande, and M. Wani. "Elicitation based enhancement of solasodine production in in-vitro cultures of different Solanum species." Journal of Environmental Biology 44, no. 2 (2023): 167–74. http://dx.doi.org/10.22438/jeb/44/2/mrn-4011.

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Aim: To study the enhancement of solasodine content using elicitors such as NaCl, pectin, salicylic acid and yeast extract in cell suspension cultures of Solanum incanum, Solanum nigrum, Solanum surattense and Solanum villosum. Methodology: In-vitro callus induction from leaf explants was carried out on MS media supplemented with auxin, 2, 4- Dichlorophenoxyacetic acid (2.0 mg l-1). MS liquid medium supplemented with 2, 4-D (2.0 mg l-1) and varied concentrations of different elicitors were used for cell suspension culture. Results: The elicitor NaCl (150 mM) indicated maximum increment in sola
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4

Patel, Kinjal, and Chaitanya Bhatt. "DEVELOPMENT AND VALIDATION OF A HPTLC METHOD FOR SIMULTANEOUS DENSITOMETRIC ANALYSIS OF GLYCYRRHETIC ACID AND SOLASODINE IN HERBAL DRUG FORMULATION." International Journal of Current Pharmaceutical Research 9, no. 4 (2017): 29. http://dx.doi.org/10.22159/ijcpr.2017v9i4.20752.

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Objective: To develop and validate a simple, precise, selective, and accurate high-performance thin layer chromatographic method for simultaneous densitometric analysis of glycyrrhetic acid and solasodine in the polyherbal formulation.Methods: The method was developed using HPTLC silica gel GF254precoated aluminium plate as the stationary phase and Chloroform: Methanol (9:1 v/v) as the mobile phase. Quantization of glycyrrhetic acid was achieved by determining the area under the curve at 267 nm using CAMAG TLC Scanner and CATS 3 software. Since the structure of solasodine lacks conjugated doub
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5

Paczkowski, C., M. Kalinowska, and Z. A. Wojciechowski. "UDP-glucose:solasodine glucosyltransferase from eggplant (Solanum melongena L.) leaves: partial purification and characterization." Acta Biochimica Polonica 44, no. 1 (1997): 43–53. http://dx.doi.org/10.18388/abp.1997_4438.

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Uridine 5'-diphosphoglucose-dependent glucosyltransferase which catalyzes the glycosylation of solasodine i.e. UDP-glucose:solasodine glucosyltransferase, is present in leaves, roots, unripe fruits and unripe seeds of eggplant (Solanum melongena L.). The glucosylation product is chromatographically identical with authentic solasodine 3 beta-D-monoglucoside, a putative intermediate in the biosynthesis of solasodine-based glycoalkaloids characteristic of the eggplant. The enzyme was purified about 50-fold from crude cytosol fraction of eggplant leaves by ammonium sulphate precipitation and colum
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6

Samy, B. Gopal, S. Karthika Devi, and J. Priya Dharshini. "MOLECULAR DOCKING OF BREAST CANCER RECEPTORS AGAINST ANTI-CANCER DRUG SOLASODINE." Applied Biological Research 26, no. 1 (2024): 58–65. http://dx.doi.org/10.48165/abr.2024.26.01.8.

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Cancer is a deadly disease that occurs in skin, pancreas, breast, and other body parts. Breast cancer is nowadays more common and can develop from various cell lines like MCF-7, MDA-MB-231, BT-20, etc. Early diagnosis and treatment can reduce the frequency of fatalities due to breast cancer, but early cancer screenings are often postponed due to erroneous information, fear, and ignorance. In the present work, we used molecular docking to find out the effect of solasodine binding on different cancer receptors. Solasodine was extracted from black nightshade (Solanum nigrum), a weed that was long
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7

Trivedi, Priti D., Brijesh C. Patel, Shivprakash Rathnam, and Kilambi Pundarikakshudu. "A Validated Liquid Chromatographic Method for Estimation of Solasodine in Various Solanum Species and Market Formulations." Journal of AOAC INTERNATIONAL 89, no. 6 (2006): 1519–23. http://dx.doi.org/10.1093/jaoac/89.6.1519.

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Abstract This paper describes an improved liquid chromatographic (LC) method involving a prechromatographic derivatization step for the estimation of solasodine from berries of various Solanum species, market samples of Solanum xanthocarpum herb, extract, and its market formulations. Solasodine has heterocyclic nitrogen but has no conjugated double bonds in its structure. However, in all reported LC methods, detection was made in the ultraviolet range of 200213 nm. In the present study, a prechromatographic derivatization of solasodine was done by forming an ion-pair complex of the heterocycli
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8

Moreira, C. B., S. S. Lima, M. A. Esquibel, and A. Sato. "Solasodine accumulation in regenerated plants of Solanum torvum Sw." Revista Brasileira de Plantas Medicinais 12, no. 1 (2010): 73–79. http://dx.doi.org/10.1590/s1516-05722010000100011.

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A nodal segment culture was developed in order to assess Solanum torvum Sw. regeneration and solasodine levels. The influence of auxins (indoleacetic acid, 1-Naphthaleneacetic acid) and benzyl adenine on S. torvum growth in micropropagation was investigated. A nodal segment culture was initiated with seeds germinated in MS basal medium added of GA3 and grown in different concentrations of IAA, IAA + BAP and NAA + BAP. Sixty-day-old plants from the in vitro culture were collected, frozen and lyophilized; then, the methyl orange method was used to quantify solasodine for the spectrophotometric a
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9

Baihaqi, Ahmad Uzair, Hany Handajani, Wanda Rahmania, and Heryanto Heryanto. "Potentiality of Solanum torvum as an agent of feminization Anabas testudineus Bloch 1792: a Review." Omni-Akuatika 18, S1 (2022): 34. http://dx.doi.org/10.20884/1.oa.2022.18.1.901.

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Climbing perch (Anabas testudineus) has a high economic value. Females grow faster than males. Sex reversal is one of genetic engineering by manipulating their hormone that is able to change the phenotype from male to female or vice versa. “Cepoka” eggplant (Solanum torvum) has been known as a medicinal and kitchen ingredient. Phytochemical test on S. torvum showed revealed that this plant contains tannins, saponins, flavonoids, steroids, alkaloids and terpenoids. Solasodine is a steroidial glycoalkaloid compound contained in S. torvum which has anti-fertility effects. Besides solasodine,
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10

Jayakumar, K., and K. Murugan. "Purified solasodine from Solanum mauritianum Scop. and its molecular mechanism of antimetastatic potential." Journal of Phytopharmacology 6, no. 4 (2017): 251–59. http://dx.doi.org/10.31254/phyto.2017.6409.

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Breast cancer has been identified as one of the most common type of cancer among female human population. General treatment approaches against breast cancer includes radio, chemo or hormonal therapy. Unfortunately, most of these approaches ameliorate the target and evoke adverse side effects. Phytochemicals including alkaloids are reported to alleviate ailments with no or little side effects. Bug weed (Solanum mauritianum Scop.), an evergreen medium sized tree of Solanaceae, a native of South America was used for treating different pain disorders. Glycoalkaloid solasodine was isolated and puri
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11

Lin, Li, Wen Yang, Xing Wei, et al. "Enhancement of Solasodine Extracted from Fruits of Solanum nigrum L. by Microwave-Assisted Aqueous Two-Phase Extraction and Analysis by High-Performance Liquid Chromatography." Molecules 24, no. 12 (2019): 2294. http://dx.doi.org/10.3390/molecules24122294.

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Background: Solasodine is a major bioactive ingredient in Solanum nigrum L. that has strong pharmacological characteristics. Therefore, the development of a simple and effective extraction method for obtaining solasodine is highly important. This study aims to provide a rapid and effective method for extracting solasodine from Solanum nigrum L. by microwave-assisted aqueous two-phase extraction (MAATPE). Methods: First, the high-performance liquid chromatography (HPLC) conditions were established for the detection of solasodine. Then, the aqueous two-phase system (ATPS) compositions were exami
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12

Patel, V.B., I.S. Rathod, J.M. Patel, and M.R Brahmbhatt. "Phytochemical Investigation and Molecular Modelling of Steroidal Glycoalkaloid from Solanum Xanthocarpum." International Journal of Current Pharmaceutical Review and Research 2, no. 1 (2011): 07–011. https://doi.org/10.5281/zenodo.12698939.

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The kantakari having a botanical name is Solanum xanthocarpum, synonym Solanumsurattense and it belongs to family solanaceae. A dried ripe berries containing more amountof glycoalkaloid compare to all parts of the plant. Glycoalkaloids consist of perhydro 1, 2-cyclopentanophenanthrene nucleus, the solanum alkaloid having N- analog of steroidalsaponins. The isolated compounds were evaluated by physical and chemical methodsandfurther elucidated by analytical specification using UV, Infrared and Mass spectroscopicmethods. Molecular Modelling and comparison study used as a pottasium sparing diuret
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13

da Silva, Ana Raquel Pereira, Maria do Socorro Costa, Nara Juliana Santos Araújo, et al. "Potentiation of Antibiotic Action and Efflux Pump Inhibitory Effect on Staphylococcus aureus Strains by Solasodine." Antibiotics 11, no. 10 (2022): 1309. http://dx.doi.org/10.3390/antibiotics11101309.

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A worrisome fact is the increase in microbial resistance, which has as its main cause the indiscriminate use of antibiotics. Scientific studies have investigated bioactive compounds such as steroidal sapogenins, in the perspective of new beneficial alternatives for the control of bacterial resistance. Therefore, the objective of this work was to verify the antibacterial activity as well as the modifying action of antibiotics associated with solasodine and its ability to inhibit the efflux pump mechanism in strains of Staphylococcus aureus. Tests were performed to verify the minimum inhibitory
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14

Khaserao, Satish, and Rahul Somani. "EVALUATION OF ANTI-OBESITY ACTIVITY OF SOLASODINE IN HIGH FAT DIET-INDUCED OBESITY IN RAT." International Journal of Pharmacy and Pharmaceutical Sciences 9, no. 3 (2017): 23. http://dx.doi.org/10.22159/ijpps.2017v9i3.16025.

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Objective: This study was planned to study the anti-obesity activities of solasodine on high fat (HF) diet-induced obese rats.Methods: Wistar rats were divided into six groups. Control group (Group 1) received normal diet and 0.5 % CMC (5 ml/kg). HF control group (Group 2) received HF diet. Group 3 received orlistat (25 mg/kg body weight per oral). Group 4, 5 and 6 received 25, 50 and 100 mg/kg body weight solasodine respectively. Treatment was given for 6 w to the respective group along with HF diet. Body weight, food intake and abdomen circumference was measured every week for 6 w. On day 42
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15

Wojtkielewicz, Agnieszka, Urszula Kiełczewska, and Jacek W. Morzycki. "Two-step Synthesis of Solasodine Pivalate from Diosgenin Pivalate." Molecules 24, no. 6 (2019): 1132. http://dx.doi.org/10.3390/molecules24061132.

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A two-step synthesis of solasodine pivalate from diosgenin pivalate is described. The key transformation involves the reaction of diosgenin pivalate with benzyl carbamate (CbzNH2) promoted by TMSOTf. During the reaction the F-ring of the spiroketal moiety opens up with a simultaneous introduction of a Cbz-protected amino group in position 26. A one-pot deprotection of 26-amine with AcBr/BuOH followed by the N-cyclization affords solasodine pivalate in 45% overall yield.
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16

Cham, Bill E. "Solasodine, Solamargine and Mixtures of Solasodine Rhamnosides: Pathway to Expansive Clinical Anticancer Therapies." International Journal of Clinical Medicine 08, no. 12 (2017): 692–713. http://dx.doi.org/10.4236/ijcm.2017.812064.

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17

Islam, Md Ashraful, Md Muntasir Bin Mohi Uddin, Md Golam Rasul, Md Ahsanul Haque Swapon, Minhaz Ahmed, and Mehfuz Hasan. "In Vitro Screening and Field Performance of EMS-Treated Eggplants for the Selection of Shoot and Fruit Borer-Resistant Plants." Agronomy 12, no. 8 (2022): 1832. http://dx.doi.org/10.3390/agronomy12081832.

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The shoot and fruit borer has asserted itself as a severe pest of eggplant. In vitro mutagenesis is an excellent method for producing mutants resistant to biotic and abiotic stresses. This study aimed to create eggplant mutants that were resistant to shoot and fruit borer infestation. In the Murashige and Skoog (MS) medium, two genotypes, including a landrace, were treated with varying amounts of EMS. Among the treatments, MS medium supplemented with 2% EMS demonstrated the most favorable effect. Explant performance dropped by up to 1.5% with an increase in EMS in the medium. The 2% EMS dose w
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18

Amir, Mohd, Niyaz Ahmad, Mohammad Sarafroz, Mahvish Jamal, Faheem Hyder Pottoo, and Mohd Mujeeb. "In Vitro Propagation, Development and Validation of HPTLC Method for Quantification of Steroidal Glycoalkaloid Solasodine in In Vitro Culture and Plant Parts of Solanum Nigrum." Oriental Journal of Chemistry 34, no. 6 (2018): 2728–34. http://dx.doi.org/10.13005/ojc/340606.

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Solanum nigrum Linn. (Family: solanaceae), has medicinal values, commonly exploited for its active constituents which are of high pharmaceutical importance. The plant contains different type of natural compounds, and one of most important glycoalkaloid in S. nigrum is solasodine. Nodal segment of S. nigrum was cultured on MS media added with several concentrations of 2, 4-dichlorophenoxy acetic acid (2, 4- D) (0.5ppm –2ppm) for callus induction and development. For shoot induction, MS medium complemented with different dilutions of 6- benzyl adenine (6- BA) (0.5ppm–2ppm) was used. A novel, rap
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19

Jastrzebska, Izabella, and Jacek W. Morzycki. "Some observations on solasodine reactivity." Steroids 127 (November 2017): 13–17. http://dx.doi.org/10.1016/j.steroids.2017.08.015.

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20

Vogel, H., A. Jatisatienr, and W. Horn. "BreedingSolanum laciniatumfor High Solasodine Yield." Planta Medica 59, S 1 (1993): A697—A698. http://dx.doi.org/10.1055/s-2006-959990.

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21

Putalun, W., F. Taura, W. Qing, H. Matsushita, H. Tanaka, and Y. Shoyama. "Anti-solasodine glycoside single-chain Fv antibody stimulates biosynthesis of solasodine glycoside in plants." Plant Cell Reports 22, no. 5 (2003): 344–49. http://dx.doi.org/10.1007/s00299-003-0689-3.

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22

Nawłoka, Paulina, Małgorzata Kalinowska, Cezary Paczkowski, and Zdzisław A. Wojciechowski. "Evidence for essential histidine and dicarboxylic amino-acid residues in the active site of UDP-glucose : solasodine glucosyltransferase from eggplant leaves." Acta Biochimica Polonica 50, no. 2 (2003): 567–72. http://dx.doi.org/10.18388/abp.2003_3710.

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Effects of several chemical probes selectively modifying various amino-acid residues on the activity of UDP-glucose : solasodine glucosyltransferase from eggplant leaves was studied. It was shown that diethylpyrocarbonate (DEPC), a specific modifier of histidine residues, was strongly inhibitory. However, in the presence of excessive amounts of the enzyme substrates, i.e. either UDP-glucose or solasodine, the inhibitory effect of DEPC was much weaker indicating that histidine (or histidines) are present in the active site of the enzyme. Our results suggest also that unmodified residues of glut
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23

Bushway, Rodney J., and Lewis B. Perkins. "Identification of an Impurity in Commercial Sources of the Tomato Glycoalkaloid Tomatine." Journal of AOAC INTERNATIONAL 78, no. 3 (1995): 691–92. http://dx.doi.org/10.1093/jaoac/78.3.691.

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Abstract Three commercial sources of tomatine showed 2 peaks of approximately equal size when determined by liquid chromatography (LC). Analysis by liquid chromatography/mass spectroscopy (LC/MS) showed one LC peak having an [M + H] ion at 1035, which corresponds to tomatine. The other peak had an [M + H] ion at 1033, which indicates a tomatine-like molecule that has tomatidenol for the aglycone instead of tomatidine or solasodine. Ultraviolet data support a delta C-5–C-6 double bond in the aglycone. LC of tomatine hydrolysate indicated the presence of tomatidine and tomatidenol and the absenc
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24

S, PAL, GUPTA P.K, and SINGH K.K. "CORRELATION AND PATH COEFFICIENT ANALYSIS AMONG QUANTITATIVE CHARACTERS OF Solanum Khasianum CLARKE." Madras Agricultural Journal 81, October (1994): 523–26. http://dx.doi.org/10.29321/maj.10.a01570.

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Correlation and path coefficient analysis among 14 characters of 30 genotypes of Skhasianum have been studied. Phenotypic correlation of berry yield per plant exhibited positive and highly significant correlation with number of berries per bunch, plant height, number of branches, plant spread, number of berries per plant, volume per beny, weight per berry and solasodine yield per plant. Positive significant genotypic correlations were also observed in all these attributes except volume per berry. Direct positive contribution of days to fruting, days to maturity, number of flowers per bunch, nu
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Wulansari, Desi, Yudit Oktanella, Viski Fitri Hendrawan, and Galuh Chandra Agustina. "Solasodine and Gosipol Effectivity as a Male Contraception Inhibit LH Expression and Spermatogenesis in Rat." Veterinary Biomedical and Clinical Journal 1, no. 2 (2019): 51–59. http://dx.doi.org/10.21776/ub.vetbioclinj.2019.001.02.7.

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Rabies related to increasing canine population in Bali. Uncontrolled wild animal populations caused disease transmission from animal to human. Various attempt at population control are carried out such as the use of natural contraception. Some compounds are known to have potential as antifertility are solasodine and gosipol. Solasodine is known have an antifertility affect. Gosipol, fenolic compound in Ceiba pentandra, inhibits spermatogenesis, reduce sperm concentration, motility and viability. This research aims to compare effectiveness of terong cepoka and Ceiba pentandra as antifertility.
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26

Turdybekov, K. M., S. V. Lindeman, Yu T. Struchkov, A. M. Gazaliev, S. N. Balitskii, and M. Zh Zhurinov. "Molecular structure of the alkaloid solasodine." Chemistry of Natural Compounds 25, no. 1 (1989): 75–76. http://dx.doi.org/10.1007/bf00596706.

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Tanaka, Hiroyuki, Waraporn Putalun, and Yukihiro Shoyama. "Fingerprinting of Natural Product by Eastern Blotting Using Monoclonal Antibodies." Chromatography Research International 2012 (February 6, 2012): 1–7. http://dx.doi.org/10.1155/2012/130732.

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We succeeded in developing the fingerprint of natural product by eastern blotting using monoclonal antibodies. After developing and separating them on a TLC plate, solasodine glycosides are oxidized by NaIO4 and reacted with a protein to give conjugates which are recognized with anti-solamargine monoclonal antibody (MAb). Anti-solamargine MAb having wide cross-reactivity can stain and detect all solasodine glycosides by fingerprint. Different sensitivity between solamargine and solasonine was observed. The detection limit was 1.6 ng of solasonine. The hydrolysed products of solamargine were de
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Tuan Anh, Hoang Le, Phuong Thao Tran, Do Thi Thao, et al. "Degalactotigonin, a Steroidal Glycoside from Solanum nigrum, Induces Apoptosis and Cell Cycle Arrest via Inhibiting the EGFR Signaling Pathways in Pancreatic Cancer Cells." BioMed Research International 2018 (December 16, 2018): 1–9. http://dx.doi.org/10.1155/2018/3120972.

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Degalactotigonin (1) and three other steroidal compounds solasodine (2), O-acetyl solasodine (3), and soladulcoside A (4) were isolated from the methanolic extract of Solanum nigrum, and their chemical structures were elucidated by spectroscopic analyses. The isolated compounds were evaluated for cytotoxic activity against human pancreatic cancer cell lines (PANC1 and MIA-PaCa2) and lung cancer cell lines (A549, NCI-H1975, and NCI-H1299). Only degalactotigonin (1) showed potent cytotoxicity against these cancer cell lines. Compound 1 induced apoptosis in PANC1 and A549 cells. Further study on
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Renadi, Sedin, Anindita Tri Kusuma Pratita, Richa Mardianingrum, and Ruswanto Ruswanto. "The Potency of Alkaloid Derivates as Anti-Breast Cancer Candidates: In Silico Study." Jurnal Kimia Valensi 9, no. 1 (2023): 89–108. http://dx.doi.org/10.15408/jkv.v9i1.31481.

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Breast cancer is the most frequent malignancy in women worldwide. One of the target receptors for the treatment of breast cancer are estrogen, progesterone, and HER2 receptors. An alternative treatment using natural ingredients has been developed, one of which is alkaloid compounds. This study aims to determine the activity of alkaloid compounds as anti-breast cancer agents through an in-silico method. Virtual screening (AutoDock Vina), molecular docking (AutoDock Tools), molecular dynamics (Desmond), scanning Lipinski's rule of five, as well as pharmacokinetic and toxicity parameters, were pe
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Kiełczewska, Urszula, Jacek W. Morzycki, Lucie Rárová, and Agnieszka Wojtkielewicz. "The synthesis of solasodine F-homo-analogues." Organic & Biomolecular Chemistry 17, no. 40 (2019): 9050–58. http://dx.doi.org/10.1039/c9ob01888c.

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An efficient synthesis of F-homosolasodine analogues containing the 5/7 spirohemiaminal moiety was elaborated. The method benefited from an easy opening of diosgenin F-ring and the introduction of a cyano group in position 26.
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31

Sarg, Taha M., Karl W. Glombitza, Samia S. Hafez, Nawal M. Farrag, and Fawkeya A. Abbas. "Solasodine glycosides of Solanum unguiculatum (A.) Rich." Pharmacy World & Science 17, no. 6 (1995): 191–94. http://dx.doi.org/10.1007/bf01870610.

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Chang, Wenqiang, Ying Li, Sha Zheng, Ming Zhang, Yanhui Gao та Hongxiang Lou. "Solasodine-3- O -β- d -glucopyranoside is hydrolyzed by a membrane glucosidase into active molecule solasodine against Candida albicans". Food and Chemical Toxicology 109 (листопад 2017): 356–62. http://dx.doi.org/10.1016/j.fct.2017.09.026.

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33

Srinivas, Meenakshi, and R. Krishnan. "Effect of Grafting on Solasodine Content inSolanum viarum." Planta Medica 62, no. 04 (1996): 360–61. http://dx.doi.org/10.1055/s-2006-957905.

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34

Tsoulpha, Parthena, and Pauline M. Doran. "Solasodine production from self-immobilised Solanum aviculare cells." Journal of Biotechnology 19, no. 1 (1991): 99–110. http://dx.doi.org/10.1016/0168-1656(91)90077-9.

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35

Anirudhan, K., and A. S. Nair. "In vitro production of solasodine from Solanum trilobatum." Biologia plantarum 53, no. 4 (2009): 719–22. http://dx.doi.org/10.1007/s10535-009-0130-z.

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36

Patel, A. V., G. Blunden, and T. A. Crabb. "TRANSFORMATION OF SOLASODINE BY THE FUNGUS, CUNNINGHAMELLA ELEGANS." Journal of Pharmacy and Pharmacology 37, S12 (1985): 68P. http://dx.doi.org/10.1111/j.2042-7158.1985.tb14140.x.

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37

Schulz, D., U. Eilert, and A. Ehmke. "Characterization of UDP-Glucose: Solasodine Glucosyltransferase fromSolanum laciniatum." Planta Medica 59, S 1 (1993): A649. http://dx.doi.org/10.1055/s-2006-959903.

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Oktanella, Yudit, Husayn Satria Nugroho, Desi Wulansari, Viski Fitri Hendrawan, Galuh Chandra Agustina, and Agri Kaltaria Anisa. "Infertility Impact of Cotton Seeds (Ceiba pentandra) and Eggplant Cepoka (Solanum torvum) on the Nfkb Expression and Seminiferous Tubules Diameter." Journal of Experimental Biology and Agricultural Sciences 10, no. 5 (2022): 1109–14. http://dx.doi.org/10.18006/2022.10(5).1109.1114.

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The presence of the solasodine and gossypol compounds in Kapok seeds (Ceiba pentandra) and cepoka eggplant (Solanum torvum) suggest the use of these two as an herbal contraceptive ingredient in male animal fertility. This study aimed to determine the effect of cepoka eggplant extract (S. torvum) and kapok seed (C. pentandra) on infertility in rats (Rattus norvegicus) through NFkB expression and seminiferous tubule diameter. The study was carried out on 75 to 90 days old male Wistar rats having 150-200 grams of body weight. The experimental design used in this study was a completely randomized
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Chauhan, Kinjal, Navin Sheth, Vishavas Ranpariya, and Sachin Parmar. "Anticonvulsant activity of solasodine isolated fromSolanum sisymbriifoliumfruits in rodents." Pharmaceutical Biology 49, no. 2 (2010): 194–99. http://dx.doi.org/10.3109/13880209.2010.508499.

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Indrayanto, Gunawan, and Noor Cholies. "Influence of Fruit Size ofSolanum Wrightiion its Solasodine Content." Planta Medica 51, no. 05 (1985): 470. http://dx.doi.org/10.1055/s-2007-969563.

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Maddala, Madhavi, Baburao Gundi, and Suhasini Gudimalla. "Solasodine phytocompound controlled the food pest Tribolium castaneum growth." Journal of Entomological Research 44, no. 2 (2020): 227. http://dx.doi.org/10.5958/0974-4576.2020.00040.7.

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42

Loc, Nguyen Hoang, and Le Thi Ha Thanh. "Solasodine production from cell culture of Solanum hainanense Hance." Biotechnology and Bioprocess Engineering 16, no. 3 (2011): 581–86. http://dx.doi.org/10.1007/s12257-010-0118-8.

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43

Shakirov, R., Yu R. Mirzaev, Kh M. Bobakulov, and N. D. Abdullaev. "Glycosylation of solasodine and pharmacological activity of the product." Chemistry of Natural Compounds 48, no. 4 (2012): 610–12. http://dx.doi.org/10.1007/s10600-012-0324-z.

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Drewes, F. E., J. Van Staden, and S. E. Drewes. "Benzoylation and high performance liquid chromatographic detection of solasodine." Phytochemical Analysis 3, no. 2 (1992): 85–87. http://dx.doi.org/10.1002/pca.2800030209.

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JAGGI, R. K., and V. K. KAPOOR. "ChemInform Abstract: Solasodine - Its Occurrence in Nature and Production." ChemInform 25, no. 30 (2010): no. http://dx.doi.org/10.1002/chin.199430271.

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Neszmelyi, Andras, Daisy Machytka, and M. Marruan Shabana. "13C NMR spectroscopy of solasodine glycosides from Solanum laciniatum." Phytochemistry 27, no. 2 (1988): 603–5. http://dx.doi.org/10.1016/0031-9422(88)83150-9.

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47

Al-Sinani, Sana S., and Elsadig A. Eltayeb. "Optimised Methods for Quantitative Analysis of Solasodine and its Glycoside Solamargine by High Performance Liquid Chromatography." Sultan Qaboos University Journal for Science [SQUJS] 18 (December 1, 2013): 1. http://dx.doi.org/10.24200/squjs.vol18iss0pp1-10.

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Improved and simplified HPLC conditions for the determination and quantification of both the steroidal glycoalkaloid (solamargine) and its aglycone (solasodine) are described. The best isocratic conditions were developed using a C18 column and methanol in combination with an ammonium dihydrogen phosphate buffer. The isocratic conditions were shown to be more reproducible, less time consuming and to give sharper peaks (better separation). The effects of adjusting solvent: buffer ratio, buffer pH and buffer molarity were evaluated.
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Kumar, R., M. I. Khan, M. Prasad, and Badruddeen. "Solasodine: A Perspective on their roles in Health and Disease." Research Journal of Pharmacy and Technology 12, no. 5 (2019): 2571. http://dx.doi.org/10.5958/0974-360x.2019.00432.3.

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Patel, Asmita V., Gerald Blunden, and Trevor A. Crabb. "Transformations of solasodine and derivatives of hecogenin by Cunninghamella elegans." Phytochemistry 35, no. 1 (1993): 125–33. http://dx.doi.org/10.1016/s0031-9422(00)90520-x.

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Hameed, Abdul, Shakeel Ijaz, Imran Shair Mohammad, Kiran Sher Muhammad, Naveed Akhtar, and Haji Muhammad Shoaib Khan. "Aglycone solanidine and solasodine derivatives: A natural approach towards cancer." Biomedicine & Pharmacotherapy 94 (October 2017): 446–57. http://dx.doi.org/10.1016/j.biopha.2017.07.147.

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