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Journal articles on the topic 'Solubility of HCl'

Author: Grafiati

Published: 4 June 2021

Last updated: 16 February 2022

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1

Copur, Mehmet, Sabri Colak, and Sinan Yapici. "Solubility of stibnite ore in HCl solutions." Industrial & Engineering Chemistry Research 34, no. 11 (1995): 3995–4002. http://dx.doi.org/10.1021/ie00038a040.

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2

Williams, Leah R., and David M. Golden. "Solubility of HCL in sulfuric acid at stratospheric temperatures." Geophysical Research Letters 20, no. 20 (1993): 2227–30. http://dx.doi.org/10.1029/93gl02607.

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3

Dominé, Florent, Emmanuel Thibert, Frank Van Landeghem, Eric Silvente, and Patrick Wagnon. "Diffusion and solubility of HCl in ice: preliminary results." Geophysical Research Letters 21, no. 7 (1994): 601–4. http://dx.doi.org/10.1029/94gl00512.

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4

Prakash, K., P. Narayana Raju, K. Shanta Kumari, and M. Lakshmi Narasu. "Solubility and Dissolution Rate Determination of Different Antiretroviral Drugs in Different pH Media Using UV Visible Spectrophotometer." E-Journal of Chemistry 5, s2 (2008): 1159–64. http://dx.doi.org/10.1155/2008/125917.

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Solubility and dissolution rate of three antiretroviral drugs such as lamivudine, zidovudine and stavudine was studied in four media having different pH. The samples were analyzed by usingUVVisible spectrophotometer. lamivudine shows more solubility that is 276.08 mg/mL in 0.01 N HCl. Stavudine showing highest solubility that is 101.23 mg/mL in pH 4.5 acetate buffer. Zidovudine showing highest solubility that is 28.90 mg/mL in both water and 0.01 N HCl. All three drugs showing lower solubility in pH 6.8 phosphate buffer. Lamivudine and stavudine showing good dissolution rate in all media and s

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5

Li, Yahong, Pengsheng Song, Shuping Xia, Wu Li, and Shiyang Gao. "Solubility prediction for the HCl–MgCl2–H2O system at 40 ∘C and solubility equilibrium constant calculation for HCl ⋅ MgCl2 ⋅ 7H2O at 40 ∘C." Calphad 30, no. 1 (2006): 61–64. http://dx.doi.org/10.1016/j.calphad.2005.10.008.

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6

Skiba, G. S., Yu A. Bezymyanova, and N. B. Voskoboinikov. "Solubility in the systems AlCl3-SrCl2-HCl-H2O and NaCl-SrCl2-HCl-H2O at 25°C." Russian Journal of Inorganic Chemistry 52, no. 9 (2007): 1464–67. http://dx.doi.org/10.1134/s0036023607090264.

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7

Mittal, Ankit, Manish Yadav, Dinesh Choudhary, and Birendra Shrivastava. "ENHANCEMENT OF SOLUBILITY OF LURASIDONE HCL USING SOLID DISPERSION TECHNIQUE." International Journal of Research in Ayurveda & Pharmacy 5, no. 5 (2014): 632–37. http://dx.doi.org/10.7897/2277-4343.055129.

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8

Fein, Jeremy B., and John V. Walther. "Calcite solubility and speciation in supercritical NaCl-HCl aqueous fluids." Contributions to Mineralogy and Petrology 103, no. 3 (1989): 317–24. http://dx.doi.org/10.1007/bf00402918.

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9

Darusman, Fitrianti, Taufik Muhammad Fakih, and Gina Fuji Nurfarida. "Identification of the Glimepiride and Metformin Hydrochloride Physical Interaction in Binary Systems." Borneo Journal of Pharmacy 4, no. 2 (2021): 110–16. http://dx.doi.org/10.33084/bjop.v4i2.1826.

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Glimepiride is often combined with metformin HCl as an oral antidiabetic in type II diabetes mellitus, which provides a complementary and synergistic effect with multiple targets for insulin secretion. Glimepiride includes class II of BCS, which solubility practically insoluble in water but high permeability, which will impact the drug's small bioavailability. In contrast, metformin HCl includes class III of BCS, which has a high solubility in water, but low permeability is absorbed approximately 50-60% in the digestive tract given orally. The co-crystallization method can be used to improve t

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10

Kumar, S. Sudalai, Ranjit Thakuria, and Ashwini Nangia. "Pharmaceutical cocrystals and a nitrate salt of voriconazole." CrystEngComm 16, no. 22 (2014): 4722–31. http://dx.doi.org/10.1039/c3ce42324g.

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Novel crystalline forms of voriconazole are identified with improved aqueous solubility. The dinitrate salt of voriconazole exhibited 10 fold higher solubility and 3 times faster dissolution rate in 0.1 N HCl medium compared to the reference drug.

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11

Vasoya, Jaydip M., Ankita V. Shah, and Abu T. M. Serajuddin. "Investigation of possible solubility and dissolution advantages of cocrystals, I: Aqueous solubility and dissolution rates of ketoconazole and its cocrystals as functions of pH." ADMET and DMPK 7, no. 2 (2019): 106–30. http://dx.doi.org/10.5599/admet.661.

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Since there are conflicting reports in the literature on solubility and dissolution advantages of cocrystals over free forms, we systematically studied solubility and intrinsic dissolution rates of a weakly basic drug, ketoconazole, and its cocrystals with fumaric acid and succinic acid as functions of pH to determine what advantages cocrystals provide. pH-solubility profiles were determined in two different ways: one by lowering pH of ketoconazole aqueous suspensions using HCl, fumaric acid and succinic acid, and the other by adjusting pH of cocrystal suspensions using respective coformer aci

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12

Knyazeva, A. I., G. S. Skiba, and N. B. Voskoboinikov. "Solubility in the PrCl3-SmCl3-HCl-H2O System at 25°C." Russian Journal of Inorganic Chemistry 54, no. 1 (2009): 125–27. http://dx.doi.org/10.1134/s0036023609010203.

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13

Knyazeva, A. I., G. S. Skiba, and N. B. Voskoboinikov. "Solubility in the LaCl3-YbCl3-HCl-H2O System at 25°C." Russian Journal of Inorganic Chemistry 53, no. 3 (2008): 430–33. http://dx.doi.org/10.1134/s0036023608030169.

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14

Knyazeva, A. I., G. S. Skiba, and N. B. Voskoboinikov. "Solubility in the LaCl3-GdCl3-HCl-H2O system at 25°C." Russian Journal of Inorganic Chemistry 53, no. 4 (2008): 636–38. http://dx.doi.org/10.1134/s0036023608040256.

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15

Shchelokova, E. A., E. K. Kopkova, P. B. Gromov, and G. V. Korotkova. "Solubility of monohydric aliphatic alcohols in water and aqueous HCl solutions." Russian Journal of Applied Chemistry 85, no. 3 (2012): 465–69. http://dx.doi.org/10.1134/s1070427212030251.

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16

Jianu, Ofelia A., Zhaolin Wang, Greg F. Naterer, and Marc A. Rosen. "Constituent solubility and dissolution in a CuCl-HCl-H2O ternary system." Chemical Engineering Science 184 (July 2018): 209–15. http://dx.doi.org/10.1016/j.ces.2018.03.004.

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17

Rojas, John, and David Correa. "COMPARATIVE EVALUATION OF THE RELEASE PROPERTIES OF VERAPAMIL HCL AND CARBAMAZEPINE FROM MICROCRYSTALLINE CELLULOSE II PELLETS." International Journal of Pharmacy and Pharmaceutical Sciences 9, no. 10 (2017): 182. http://dx.doi.org/10.22159/ijpps.2017v9i10.21297.

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Objective: To study microcrystalline cellulose II (MCCII) as new pelletization aid for a high and low solubility drugs such as verapamil. HCl and carbamazepine, respectively.Methods: Approximately, 30 g of MCCII and drug mixtures were hydrated passed through a # 20 mesh sieved and spheronizated at a frequency of 6 Hz and residence time of 480 s. A microscopy analysis was used to evaluate the shape and size descriptors. Pellets properties such as compressibility, friability, density, flowability and product yield were also evaluated. Drug release properties were tested according to the USP spec

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18

Rubim, Alexandre Machado, Jaqueline Bandeira Rubenick, Eduarda Gregolin, Luciane Varini Laporta, Rosimar Leitenberg, and Clarice Madalena Bueno Rolim. "Amiodarone hydrochloride: enhancement of solubility and dissolution rate by solid dispersion technique." Brazilian Journal of Pharmaceutical Sciences 51, no. 4 (2015): 957–66. http://dx.doi.org/10.1590/s1984-82502015000400021.

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abstract Amiodarone HCl is an antiarrhythmic agent, which has low aqueous solubility and presents absorption problems. This study aimed to develop inclusion complexes containing hydrophilic carriers PEG 1500, 4000 and 6000 by fusion and kneading methods in order to evaluate the increase in solubility and dissolution rate of amiodarone HCl. The solid dispersion and physical mixtures were characterized by X-ray diffraction, FT-IR spectra, water solubility and dissolution profiles. Both methods and carriers increased the solubility of drug, however PEG 6000 enhanced the drug solubility in solid d

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19

Park, Chulhun, Nileshkumar Meghani, Yongkwan Shin, et al. "Investigation of Crystallization and Salt Formation of Poorly Water-Soluble Telmisartan for Enhanced Solubility." Pharmaceutics 11, no. 3 (2019): 102. http://dx.doi.org/10.3390/pharmaceutics11030102.

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The crystal changes and salt formation of poorly water-soluble telmisartan (TEL) in various solvents were investigated for enhanced solubility, stability and crystallinity. Polymorphic behaviors of TEL were characterized by dispersing in distilled water, acetone, acetonitrile, DMSO, or ethanol using Method I: without heat and then dried under vacuum at room temperature; and Method II: with heat below boiling temperature, cooled at 5 °C, and then dried under vacuum at 40 °C. For salt formation (Method III), the following four powdered mixtures were prepared by dispersing in solution of hydrochl

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20

Luo, B. P., S. L. Clegg, Th Peter, R. Müller, and P. J. Crutzen. "HCL solubility and liquid diffusion in aqueous sulfuric acid under stratospheric conditions." Geophysical Research Letters 21, no. 1 (1994): 49–52. http://dx.doi.org/10.1029/93gl02956.

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21

Pawar, Harshal Ashok, and Pooja Rasiklal Joshi. "Development and Validation of a Discriminating In Vitro Dissolution Method for Oral Formulations Containing Satranidazole." International Journal of Spectroscopy 2014 (April 24, 2014): 1–7. http://dx.doi.org/10.1155/2014/624635.

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The development of a meaningful dissolution procedure for drug products with limited water solubility has been a challenge to the pharmaceutical industry. Satranidazole (BCS Class II drug) is a new nitroimidazole derivative with potent antiamoebic action. There is no official dissolution medium available in the literature. In the present study, parameters such as saturation solubility in different pH medium, dissolution behavior of formulations, influence of sink conditions, stability, and discriminatory effect of dissolution testing were studied for the selection of a proper dissolution mediu

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22

Gamal, Hany, Khaled Abdelgawad, and Salaheldin Elkatatny. "New Environmentally Friendly Acid System for Iron Sulfide Scale Removal." Sustainability 11, no. 23 (2019): 6727. http://dx.doi.org/10.3390/su11236727.

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Iron sulfide scale is a common problem in the oil and gas industry. The precipitation of the iron sulfide scale on the well completion tools or inside surface flow lines restricts the flow of the produced fluids and might affect the integrity of the pipelines or the surface and subsurface tools. Failure of the downhole completions tools will not only reduce the production rates but it might require workover and remedial operations that will add extra cost. The main objective of this paper is to evaluate a new environmentally friendly acid system (NEFAS) for iron sulfide scale removal using an

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23

Ain, Shabnam, V. Gupta, Babita K, Q. Ain, and J. Dahiya. "Solubility Enhancement of the Poorly Water-Soluble Antiulcer Drug Famotidine by Inclusion Complexation." International Journal of Pharmaceutical Sciences and Nanotechnology 6, no. 1 (2013): 1983–89. http://dx.doi.org/10.37285/ijpsn.2013.6.1.10.

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Aqueous solubility is a critical factor for optimum drug delivery. In the present study, we investigated the potential of drug-cyclodextrin complexation as an approach for improving the solubility and bioavailability of famotidine, an H2-receptor antagonist and acid reducing drug which has poor solubility and bioavailability. Solubility improvement of drug by β-cyclodextrin was done by simple complexation approach using physical, kneading and co-precipitation methods and compared with physical mixture. Phase solubility profile indicated that the solubility of famotidine was significantly incre

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24

De Visscher, Alex, and Jan Vanderdeelen. "Consistency issues of aqueous solubility data and solution thermodynamics of electrolytes." Pure and Applied Chemistry 77, no. 3 (2005): 619–29. http://dx.doi.org/10.1351/pac200577030619.

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For the calculation of aqueous solubility of electrolytes, thermodynamic data from different sources are required. This can lead to errors if the data are inconsistent. This study reveals that some often-used semi-empirical equations for CO2 solubility and other equilibria are inconsistent with CODATA (Committee on Data for Science and Technology) key thermodynamic data. The equations were recalculated to make them consistent with CODATA. Combining standard thermodynamic data of NaCl with the Pitzer model leads to significant deviations from the accepted experimental value at 25 °C. Owing to t

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25

McCandless, Richard, та Samuel H. Yalkowsky. "Effect of hydroxypropyl-β-cyclodextrin and pH on the solubility of levemopamil HCl". Journal of Pharmaceutical Sciences 87, № 12 (1998): 1639–42. http://dx.doi.org/10.1021/js9802143.

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26

Erkasov, R. Sh, R. M. Nesmeyanova, R. S. Orazbaeva, and S. M. Bolysbekova. "Solubility in the ZnCl2-CO(NH2)2-HCl-H2O system at 25°C." Russian Journal of Inorganic Chemistry 58, no. 2 (2013): 213–15. http://dx.doi.org/10.1134/s0036023613020046.

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27

Principe, F., and G. P. Demopoulos. "The solubility and stability of organophosphoric acid extractants in H2SO4 and HCl media." Hydrometallurgy 68, no. 1-3 (2003): 115–24. http://dx.doi.org/10.1016/s0304-386x(02)00206-2.

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28

Jones, C. B., D. J. G. Davies, and B. J. Meakin. "DETERMINATION OF CIRAZOLINE HCL-SODIUM DODECYL SULPHATE SOLUBILITY PRODUCTS BY AUTOMATED CONDUCTIOMETRIC TITRATION." Journal of Pharmacy and Pharmacology 38, S12 (1986): 57P. http://dx.doi.org/10.1111/j.2042-7158.1986.tb14286.x.

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29

Li, Zhibao, and George P. Demopoulos. "Solubility of CaSO4Phases in Aqueous HCl + CaCl2Solutions from 283 K to 353 K." Journal of Chemical & Engineering Data 50, no. 6 (2005): 1971–82. http://dx.doi.org/10.1021/je050217e.

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30

Carslaw, K. S., P. Brimblecombe, S. L. Clegg, and J. S. A. Green. "The solubility of HCl in stratospheric aqueous aerosols and the depletion of ozone." Journal of Aerosol Science 23 (January 1992): 909–12. http://dx.doi.org/10.1016/0021-8502(92)90559-e.

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31

Mazan, Valérie, Maria Yu Boltoeva, Evgeny E. Tereshatov, and Charles M. Folden III. "Mutual solubility of water and hydrophobic ionic liquids in the presence of hydrochloric acid." RSC Advances 6, no. 61 (2016): 56260–70. http://dx.doi.org/10.1039/c6ra06791c.

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32

Ayad, Magda Mohamed, Hisham Ezzat Abdellatef, Mervat Mohamed Hosny, and Nagla Abdel-Sattar Kabil. "Conductometric determination of sibutramine HCl, sumatriptan succinate and lomefloxacine HCl and the solubility products of their ion associates with molybdophosphoric acid." European Journal of Chemistry 4, no. 3 (2013): 297–302. http://dx.doi.org/10.5155/eurjchem.4.3.297-302.811.

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33

Le, Thi Hong Thuy, Nguyen Hoc Thang, Van Khoi Nguyen, Thi Luong Nguyen, and Thanh Tung Nguyen. "Effect of HCl-Alcoholic Treatment on the Modification of Jackfruit (Artocarpus heterophyllus Lam) Seed Starch." Materials Science Forum 991 (May 2020): 150–56. http://dx.doi.org/10.4028/www.scientific.net/msf.991.150.

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Starches from different sources present unknown potential for new technological applications mainly when modifications are considered. In this study, jackfruit seed starch was treated in 6% hydrochloric acid in the presence of methanol and ethanol at 40°C for 2 hour and at ancohol/starch ratio of 4/1. Granule size, granular structure and solubility of the modified starch were investigated. Results showed that the average granule size of the starch ranged from 9.22μm to 14.03 μm (in methanol) and 11.86 μm (in ethanol), some changes in the solubility and the granular morphology by scanning elect

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34

Mohammadi, Shahrzad Moattar, Ali Shayanfar, Shahram Emami, and Abolghasem Jouyban. "Effects of amount of excess solid, the type of stirring and sedimentation time on solubility of sodium phenytoin and lamotrigine." ADMET and DMPK 6, no. 4 (2018): 269–78. http://dx.doi.org/10.5599/admet.621.

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Solubility is the maximum quantity of a drug dissolved in a given volume of solvent at a specific temperature. Several factors affect equilibrium solubility. Therefore, different solubility data have been reported for a solute in a certain solvent and temperature in the literature. These variations in solubility are one of the possible reasons for unsuccessful attempts of medicinal chemists for developing models as well as deviation of experimental works for solubility prediction in aqueous, non-aqueous and solvent mixtures. The present research aim is to investigate the effect of the amount o

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35

Patil, Payal H., Veena S. Belgamwar, Pratibha R. Patil, and Sanjay J. Surana. "Solubility Enhancement of Raloxifene Using Inclusion Complexes and Cogrinding Method." Journal of Pharmaceutics 2013 (January 29, 2013): 1–9. http://dx.doi.org/10.1155/2013/527380.

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The objective of the present work was to enhance the solubility and dissolution of practically water-insoluble drug raloxifene HCl (RLX), for the same two approaches that were used. In the first approach, drug was kneaded with hydroxypropyl-β-cyclodextrin (HPβCD), and in the second one drug was cogrinded with modified guar gum (MGG). The drug-cyclodextrin complex and drug-MGG cogrind mixtures were characterized by differential scanning calorimetry, X-ray diffraction studies, scanning electron microscopy, and Fourier transform infrared spectroscopy. The solubility and dissolution study reveals

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36

Li, Zhibao, and George P. Demopoulos. "Effect of NaCl, MgCl2, FeCl2, FeCl3, and AlCl3on Solubility of CaSO4Phases in Aqueous HCl or HCl + CaCl2Solutions at 298 to 353 K." Journal of Chemical & Engineering Data 51, no. 2 (2006): 569–76. http://dx.doi.org/10.1021/je0504055.

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37

Huang, Xue Song, Xian Zhe Lin, Mo Ting Guo, and Ya Zou. "Characteristics of Piperine Solubility in Multiple Solvent." Advanced Materials Research 236-238 (May 2011): 2495–98. http://dx.doi.org/10.4028/www.scientific.net/amr.236-238.2495.

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The solution of piperine in multiple solvent including ethanol, acetic acid, water and HCl were investigated to extract more piperine from piper fruit. Piperine was determined by reverse phase high-performance liquid chromatography with Diamonsil column (C18,5 μm ,250 mm×4. 6 mm) at 343 nm. Experiment data were simulated by Allometric model and the formula is Z=0.9+ 4.54×10-10×x5.675+1.8029×y2.12848+2.37×10-10×x5.675×y2.12848(Z:sample solution,mol/mL,x: the percentage of ethanol’s volume, ml/100mL,y: the acetic acid in the authentic sample solution, g/100mL), the adj·R2=0.997, the comparative

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38

Divya, L., and Latha P. V. Keerthana. "Enhancement of Solubility of Raloxifene HCl by Formulating Immediate and Controlled Release Solid Dispersion." Asian Journal of Pharmacy and Technology 5, no. 4 (2015): 238. http://dx.doi.org/10.5958/2231-5713.2015.00034.3.

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39

Jones, Matthew W., Vladimiros G. Papangelakis, and Johann D. T. Steyl. "Kieserite Solubility in the Aqueous FeCl3+ MgCl2+ HCl System between (338 and 378) K." Journal of Chemical & Engineering Data 54, no. 7 (2009): 1986–90. http://dx.doi.org/10.1021/je800735h.

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40

Delgado, Daniel R., Edgar F. Vargas, and Fleming Martínez. "Thermodynamic Study of the Solubility of Procaine HCl in Some Ethanol + Water Cosolvent Mixtures." Journal of Chemical & Engineering Data 55, no. 8 (2010): 2900–2904. http://dx.doi.org/10.1021/je900958z.

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41

Bezymyanova, Yu A., and G. S. Skiba. "Solubility in the NaCl-ZrOCl2-HCl-H2O system at 25, 50, and 75°C." Russian Journal of Inorganic Chemistry 55, no. 8 (2010): 1301–4. http://dx.doi.org/10.1134/s0036023610080279.

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42

Knyazeva, A. I., G. S. Skiba, and N. V. Serba. "Solubility in the LaCl3-LnCl3-HCl-H2O (Ln = Pr, Nd) Systems at 25°C." Russian Journal of Inorganic Chemistry 57, no. 4 (2012): 592–95. http://dx.doi.org/10.1134/s0036023612040122.

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43

Skiba, G. S., A. I. Knyazeva, and N. V. Serba. "Solubility in the NdCl3-LnCl3-HCl-H2O systems (Ln = Sm, Gd) at 25°C." Russian Journal of Inorganic Chemistry 58, no. 10 (2013): 1250–53. http://dx.doi.org/10.1134/s0036023613100227.

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44

Schmidt, Gerald L., Thomas G. Baumgartner, Werner Fischlschweiger, Harry S. Sitren, Kamlesh M. Thakker, and James J. Cerda. "Cost Containment Using Cysteine HCl Acidification to Increase Calcium/ Phosphate Solubility in Hyperalimentation Solutions." Journal of Parenteral and Enteral Nutrition 10, no. 2 (1986): 203–7. http://dx.doi.org/10.1177/0148607186010002203.

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45

Wong, Chi Shing, Pavel Ya Tishchenko, and Wm Keith Johnson. "Solubility of Carbon Dioxide in Aqueous HCl and NaHCO3Solutions from 278 to 298 K." Journal of Chemical & Engineering Data 50, no. 3 (2005): 817–21. http://dx.doi.org/10.1021/je049716q.

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46

Al Masum, Md Abdullah, Florida Sharmin, S. M. Ashraful Islam, and Md Selim Reza. "Enhancement of Solubility and Dissolution Characteristics of Ibuprofen by Solid Dispersion Technique." Dhaka University Journal of Pharmaceutical Sciences 11, no. 1 (2012): 1–6. http://dx.doi.org/10.3329/dujps.v11i1.12480.

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In this study solid dispersions (SDs) of ibuprofen were prepared by melt dispersion technique using macrogol 4000 and macrogol 6000 as carrier. Physical mixtures (PMs) of ibuprofen were also prepared with the same carrier and in the same drug-carrier ratio (1:0.5, 1:1 and 1:1.5) to compare the dissolution profile. The solid dispersions and physical mixtures were investigated for drug loading, saturation solubility and dissolution behavior. Saturation solubility study was carried out in phosphate buffer (pH 7.2), 0.1 N HCl solution and distilled water. Solid dispersions were found effective to

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47

Kippenberger, Matthias, Gerhard Schuster, Jos Lelieveld, and John N. Crowley. "Trapping of HCl and oxidised organic trace gases in growing ice at temperatures relevant to cirrus clouds." Atmospheric Chemistry and Physics 19, no. 18 (2019): 11939–51. http://dx.doi.org/10.5194/acp-19-11939-2019.

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Abstract. The uptake of hydrochloric acid (HCl), ethanol (C2H5OH), 1-butanol (1-C4H9OH), formic acid HC(O)OH and trifluoroacetic (CF3C(O)OH) acid to growing ice surfaces was investigated at temperatures between 194 and 228 K. HCl displayed extensive, continuous uptake during ice growth, which was strongly dependent on the ice growth velocity, the temperature of the ice surface and the gas phase concentration of HCl. Trifluoroacetic acid was also observed to be trapped in growing ice, albeit approximately an order of magnitude less efficiently than HCl, whereas the adsorption and desorption kin

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48

Villagómez-Estrada, Sandra, José Francisco Pérez, Sandra van Kuijk, Diego Melo-Durán, Razzagh Karimirad, and David Solà-Oriol. "Dietary Preference of Newly Weaned Pigs and Nutrient Interactions According to Copper Levels and Sources with Different Solubility Characteristics." Animals 10, no. 7 (2020): 1133. http://dx.doi.org/10.3390/ani10071133.

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Two feeding preference experiments and an in vitro assay were performed to assess the weaned pig preference for Cu doses and sources based on their sensorial perception and on the likely post-ingestive effects of Cu. At day 7 post-weaning, a total of 828 pigs were distributed into two different experiments. In Exp.1 (dose preference) a diet with a nutritional Cu level (15 mg/kg) of Cu sulfate (SF) was pair offered with higher Cu levels (150 mg/kg) of either SF or hydroxychloride (HCl). In Exp.2 (source preference), a diet supplemented with Cu-SF at 150 mg/kg was compared to a Cu-HCl (150 mg/kg

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49

Hussein, Lna S., and Eman B. H. Al-Khedairy. "Solubility and Dissolution Enhancement of Ebastine by Surface Solid Dispersion Technique." Iraqi Journal of Pharmaceutical Sciences ( P-ISSN: 1683 - 3597 , E-ISSN : 2521 - 3512) 30, no. 1 (2021): 122–32. http://dx.doi.org/10.31351/vol30iss1pp122-132.

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Ebastine (EBS) is a non-sedating antihistamine with a long duration of action. This drug has predominantly hydrophobic property causing a low solubility and low bioavailability. Surface solid dispersions (SSD) is an effective technique for improving the solubility and dissolution rate of poorly soluble drugs by using hydrophilic water insoluble carriers. The present study aims to enhance the solubility and dissolution rate of EBS by using surface solid dispersion technique. Avicel® PH101, Avicel® PH 102, croscarmellose sodium(CCS) and sodium starch glycolate(SSG) were used as water insol

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Marczyński, Zbigniew, Sławomira Nowak, Jerzy Jambor, and Marian Mikołaj Zgoda. "Solubility and solubilizing capabilities of aqueous solutions of Extractum Taraxaci e radix cum herba aqu. siccum in light of selected values of general Hildebrand-Scatchard-Fedors theory of solubility." Herba Polonica 62, no. 4 (2016): 49–65. http://dx.doi.org/10.1515/hepo-2016-0022.

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Abstract:

Summary Introduction: The general Hildebrand-Scatchard theory of solubility supplemented by Fedors’ solubility parameter $- \delta ^{{1 \over 2}} $ was used to estimate the real solubility by −log x2 (log of the mole fraction) of phytochemicals contained in Ext. Taraxaci e radix cum herba aqu. siccum. Surface activity of aqueous solution of extracts was determined and quantified – solubilizing capabilities of solutions of cexp. ≥cmc in relation to cholesterol particle size of Ø=1.00 mm, as well as of ketoprofen were defined. Objective: The calculated value −log x2 collated with the polarity of

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