Relevant bibliographies by topics / Soluble factor

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Soluble factor'

Author: Grafiati
Published: 4 June 2021
Last updated: 17 February 2022

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Journal articles on the topic "Soluble factor"

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Carli, A. "Lipid-soluble cardiodepressant factor vs. water-soluble myocardial depressant factor-like substances in shock." American Journal of Physiology-Heart and Circulatory Physiology 261, no. 6 (December 1, 1991): H2100—H2102. http://dx.doi.org/10.1152/ajpheart.1991.261.6.h2100.

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Dale, B. "Sperm-induced calcium oscillations: Soluble factor, factors or receptors?" Molecular Human Reproduction 5, no. 1 (January 1, 1999): 1–4. http://dx.doi.org/10.1093/molehr/5.1.1.

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Godfried, Mieke H., Tom van der Poll, Jaap Jansen, Johannes A. Romijin, Jan K. M. Eeftinck Schattenkerk, Erik Endert, Sander J. H. van Deventer, and Hans P. Sauerwein. "Soluble receptors for tumour necrosis factor." AIDS 7, no. 1 (January 1993): 33–36. http://dx.doi.org/10.1097/00002030-199301000-00005.

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Ott, Ilka. "Soluble Tissue Factor Emerges From Inflammation." Circulation Research 96, no. 12 (June 24, 2005): 1217–18. http://dx.doi.org/10.1161/01.res.0000172745.09928.87.

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Reibnegger, Gilbert, Antonio Diez-Ruiz, Dietmar Fuchs, and Helmut Wachter. "Soluble tumour necrosis factor receptors as prognostic factors in cancer." Lancet 344, no. 8923 (September 1994): 681–82. http://dx.doi.org/10.1016/s0140-6736(94)92115-6.

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SOEJIMA, Kenji, Jun MIZUGUCHI, and Sadaaki IWANAGA. "Crystal Structures of Soluble Tissue Factor and Factor VIIa-Tissue Factor Complex." Japanese Journal of Thrombosis and Hemostasis 10, no. 2/3 (1999): 204–11. http://dx.doi.org/10.2491/jjsth.10.204.

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Rosen, E. M., A. Joseph, L. Jin, S. Rockwell, J. A. Elias, J. Knesel, J. Wines, J. McClellan, M. J. Kluger, and I. D. Goldberg. "Regulation of scatter factor production via a soluble inducing factor." Journal of Cell Biology 127, no. 1 (October 1, 1994): 225–34. http://dx.doi.org/10.1083/jcb.127.1.225.

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Scatter factor (SF) (also known as hepatocyte growth factor [HGF]) is a fibroblast-derived cytokine that stimulates motility, proliferation, and morphogenesis of epithelia. SF may play major roles in development, repair, and carcinogenesis. However, the physiologic signals that regulate its production are not well delineated. We found that various human tumor cell lines that do not produce SF secrete factors that stimulate SF production by fibroblasts, suggesting a paracrine mechanism for regulation of SF production. Conditioned medium from these cell lines contained two distinct scatter factor-inducing factor SF-IF activities: a high molecular weight (> 30 kD), heat sensitive activity and a low molecular weight (< 30 kD) heat stable activity. Further studies revealed that SF-producing fibroblasts also secrete factors that stimulate their own SF production. We characterized the < 30-kD SF-IF activity from ras-3T3 (clone D4), a mouse cell line that overproduces both SF and SF-IF. The < 30-kD filtrate from ras-3T3 conditioned medium induced four- to sixfold increases in expression of SF biologic activity, immunoreactive protein, and mRNA by multiple SF-producing fibroblast lines. Ras-3T3 SF-IF activity was stable to boiling, extremes of pH, and reductive alkylation, but was destroyed by proteases. We purified ras-3T3 SF-IF about 10,000-fold from serum-free conditioned medium by a combination of ultrafiltration, cation exchange chromatography, and reverse phase chromatography. The purified protein exhibited electrophoretic mobility of about 12 kD (reduced) and 14 kD (nonreduced) by SDS-PAGE. The identity of the protein was verified by elution of biologic activity from gel slices. Purified SF-IF stimulated SF production in a physiologic concentration range (about 20-400 pM). Its properties and activities were distinct from those of IL-1 and TNF, two known inducers of SF production. We suggest that SF-IF is a physiologic regulator of SF production.
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LANGKOPF, F. "Soluble tumour necrosis factor receptors as prognostic factors in cancer patients." Lancet 344, no. 8914 (July 1994): 57–58. http://dx.doi.org/10.1016/s0140-6736(94)91078-2.

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Langley, KE, LG Bennett, J. Wypych, SA Yancik, XD Liu, KR Westcott, DG Chang, KA Smith, and KM Zsebo. "Soluble stem cell factor in human serum." Blood 81, no. 3 (February 1, 1993): 656–60. http://dx.doi.org/10.1182/blood.v81.3.656.656.

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Abstract Stem cell factor (SCF) is a recently described factor active in the early stages of hematopoiesis. It can exist in membrane-bound form and in proteolytically released soluble form. The levels and nature of SCF in human serum are described. As determined by an enzyme-linked immunosorbent assay performed for 257 samples, SCF level in serum averaged 3.3 +/- 1.1 ng/mL. The serum SCF was partially purified by immunoaffinity chromatography and analyzed by glycosidase treatments in conjunction with sodium dodecyl sulfate-polyacrylamide gel electrophoresis and immunoblotting. The results show that the SCF has N- linked and O-linked carbohydrate and corresponds to the soluble form, at or about 165 amino acids in length. The findings suggest functional importance for soluble SCF in humans.
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Langley, KE, LG Bennett, J. Wypych, SA Yancik, XD Liu, KR Westcott, DG Chang, KA Smith, and KM Zsebo. "Soluble stem cell factor in human serum." Blood 81, no. 3 (February 1, 1993): 656–60. http://dx.doi.org/10.1182/blood.v81.3.656.bloodjournal813656.

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Stem cell factor (SCF) is a recently described factor active in the early stages of hematopoiesis. It can exist in membrane-bound form and in proteolytically released soluble form. The levels and nature of SCF in human serum are described. As determined by an enzyme-linked immunosorbent assay performed for 257 samples, SCF level in serum averaged 3.3 +/- 1.1 ng/mL. The serum SCF was partially purified by immunoaffinity chromatography and analyzed by glycosidase treatments in conjunction with sodium dodecyl sulfate-polyacrylamide gel electrophoresis and immunoblotting. The results show that the SCF has N- linked and O-linked carbohydrate and corresponds to the soluble form, at or about 165 amino acids in length. The findings suggest functional importance for soluble SCF in humans.
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Dissertations / Theses on the topic "Soluble factor"

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Björnberg, Flemming. "Processing of TNF-receptors to soluble receptor forms in myeloid cells." Lund : Dept. of Hematology, Lund University, 1998. http://catalog.hathitrust.org/api/volumes/oclc/39176479.html.

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Fielding, Mark. "Studies on a soluble immunosuppressive factor produced by Leishmania donovani infected macrophages." Thesis, McGill University, 1994. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=28742.

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The role of a parasite-produced or -induced soluble immunosuppressor in experimental kala azar was examined. It was found that in vivo infections with Leishmania donovani in the hamster (Mesocricetus auratus) produce a soluble immunosuppressor, which appears in the serum of the host and which reduces the proliferation of responding populations of murine splenocytes in a one-way mixed leukocyte reaction (MLR). The production in vitro infections of murine splenic macrophages from C57BL/6J ($Lsh sp{ rm s}$), C57L/J ($Lsh sp{ rm R}$) and BALB/c strains, the suppressive activity was not contained in either parasite-conditioned culture medium or in parasite extracts or from macrophages which have internalized killed parasites or inert particles and it is not blocked by the action of 2-mercaptoethanol or indomethacin in the culture medium. The suppressor was found to be able to selectively inhibit or reduce the proliferation of splenocytes of both the C57BL/6J and C57LN strains in a one way MLR, with the level of suppression being significantly greater upon splenocytes of the susceptible $Lsh sp{ rm s}$ strain. The suppression was dependent upon the genotype of the macrophages present in the responding population. The suppressor was also able to significantly inhibit the processing of human serum albumin by macrophages, to reduce the number of Ia ligands on the surfaces of macrophages and the production by these cells of IL-1 upon silica stimulation.
Significant reduction was also seen in the production of IL2 and in the expression of its receptor by PHA-stimulated T cells exposed to the suppressor. Partial purification and identification of the suppressor demonstrated that the suppressive activity was present in fractions between 30 and 50 kDa in size; the suppressor was also heat labile and freeze-thaw sensitive. The suppressive molecule(s) may therefore play a significant role in the establishment and pathology of L. donovani infections.
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Powell, Robert. "Studies on the interaction of enteroviruses with soluble decay-accelerating factor (CD55)." Thesis, University of Reading, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.286023.

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McKeeman, G. C. "The measurement of circulation soluble vascular endothelial growth factor receptor-1 (sFlt-1)." Thesis, Queen's University Belfast, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.273085.

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Prevost, Jay Michael. "Identification of the soluble granulocyte-macrophage colony stimulating factor receptor protein in vivo and development of a soluble model of the high-affinity cell surface receptor for granulocyte-macrophage colony stimulating factor." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0015/MQ52093.pdf.

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Barakauskas, Vilte Elenute. "Investigation of striatal soluble N-ethylmaleimide sensitive factor attachment receptor (SNARE) proteins in schizophrenia." Thesis, University of British Columbia, 2010. http://hdl.handle.net/2429/29150.

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Synaptic dysfunction likely contributes to abnormal brain function in schizophrenia. Patient symptoms indicate that the striatum is involved in this disease. The three neuronal soluble-NSF-attachment receptor (SNARE) proteins (SNAP-25, syntaxin-1 and VAMP) interact at the presynaptic neuronal membrane to facilitate neurotransmission, and are thus key players in synaptic function. SNARE abnormalities have already been reported in cortical and hippocampal brain regions in schizophrenia. Their involvement in striatal dysfunction has not been investigated. Normal synaptic function requires the SNAREs to physically interact with each other, but little is known about how altered SNARE protein levels in schizophrenia relate to SNARE protein interactions. Multiple isoforms of each SNARE exist in the brain, may affect SNARE protein interactions and synaptic transmission differently, and may diverge functionally. SNARE isoform expression in schizophrenia is unknown. Thus, abnormalities in SNARE protein expression or function may underlie or contribute to brain dysfunction and disease. In this thesis, SNARE protein levels were measured in human post mortem brain samples of schizophrenia subjects for the first time in the striatum. The functional consequences of SNARE alterations were investigated by developing a novel ELISA assay to measure SNARE protein interactions. The possible confounding effects of medications were addressed in several ways, including the use of striatal tissue from animals exposed to antipsychotic medications. Alterations in SNAP-25 and syntaxin-1 protein levels were further dissected by measuring protein isoforms. Syntaxin-1 isoforms were assayed by quantitative immunoblotting. A mass-spectrometry based assay was developed and used to measure SNAP-25 protein isoform levels. The results of these investigations suggest that SNARE protein alterations in schizophrenia are restricted to distinct functional regions of the striatum, perturb SNARE protein interactions, involve specific protein isoforms, and may occur independent of patient treatment with antipsychotic medications. Furthermore, these studies contribute a new, high-throughput method for measuring SNARE protein interactions, and for the first time, a means of detecting and quantifying SNAP-25 isoforms in brain tissue.
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Ku, Min-Chi [Verfasser]. "Interaction of glioma cells and intrinsic brain cells - soluble factor mediated / Min-Chi Ku." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2013. http://d-nb.info/1031098291/34.

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Kuhl, Philip R. "Synthesis of a biologically active tethered growth factor surface and comparison with soluble delivery." Thesis, Massachusetts Institute of Technology, 1997. http://hdl.handle.net/1721.1/46122.

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Wegner, Alexander. "The construction of finite soluble factor groups of finitely presented groups and its application." Thesis, University of St Andrews, 1992. http://hdl.handle.net/10023/12600.

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Computational group theory deals with the design, analysis and computer implementation of algorithms for solving computational problems involving groups, and with the applications of the programs produced to interesting questions in group theory, in other branches of mathematics, and in other areas of science. This thesis describes an implementation of a proposal for a Soluble Quotient Algorithm, i.e. a description of the algorithms used and a report on the findings of an empirical study of the behaviour of the programs, and gives an account of an application of the programs. The programs were used for the construction of soluble groups with interesting properties, e.g. for the construction of soluble groups of large derived length which seem to be candidates for groups having efficient presentations. New finite soluble groups of derived length six with trivial Schur multiplier and efficient presentations are described. The methods for finding efficient presentations proved to be only practicable for groups of moderate order. Therefore, for a given derived length soluble groups of small order are of interest. The minimal soluble groups of derived length less than or equal to six are classified.
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Ghosh, Deepraj. "Soluble factor mediated manipulation of mesenchymal stem cell mechanics for improved function of cell-based therapeutics." Diss., Georgia Institute of Technology, 2014. http://hdl.handle.net/1853/54032.

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Mesenchymal stem cells (MSCs) are bone marrow derived multipotent cells with the ability to self-renew and differentiate into multiple connective cell lineages. In vivo, MSCs travel from the bone-marrow to the inflammatory sites and actively participate in remodeling and regeneration process under the influence of soluble growth factors. Due to these inherent properties, MSCs have emerged as an ideal candidate for diverse regenerative therapeutic applications. The development of MSC-based therapies requires in vitro expansion of MSCs; however, MSC expansion results in phenotypical changes that have limited its efficacy upon reintroduction in vivo. In order to increase the efficacy of MSC-based therapeutics, it is critical for us to improve the current understanding of MSC interactions with its niche specific factors and explore new methods to enhance MSC function in vivo. We used tumor conditioned media, which contains soluble factors secreted by tumor cells in culture (TCM), and inflammatory niche-specific soluble factors, such as platelet derived growth factor (PDGF) and transforming growth factor-β1 (TGF-β1), to characterize the mechanical response of MSCs. The intracellular mechanical properties of MSCs were dramatically altered in response to soluble factors and MSCs displayed cytosolic stiffening in response to TCM and TGF-β1. Although PDGF treated cells did not elicit any mechanical response, blocking PDGF signaling with a small molecule inhibitor reversed the stiffening response in TGF-β1 treated cells, indicating crosstalk between these two pathways is essential in TGF-β1 mediated cell stiffening. Furthermore, a genome-wide microarray analysis revealed TGF-β1 dependent regulation of cytoskeletal actin-binding protein (ABP) genes. Actin crosslinking and bundling protein genes, which regulate cytosolic rheology through changes in semiflexible actin polymer meshworks, were upregulated with TGF-β1 treatment. Since TGF-β1 treatment profoundly altered the MSC phenotype after relatively short exposure times, we sought to understand if pretreated cells could sustain these enhanced characteristics leading to higher efficacy in vivo. We found that MSCs pretreated with TGF-β1 displayed enhanced adhesive properties while maintaining the expression profile of surface adhesion molecules even after removal of stimulus. Additionally, pretreated MSCs exposed to lineage specific induction media, demonstrated superior differentiation potential along multiple lineages. Based on the large number of sustained changes, TGF-β1 pretreated cells were used to treat full thickness skin wounds for in vivo wound healing model to determine their therapeutic efficacy. TGF-β1 pretreated MSCs increased wound closure rate and displayed enhanced migration of MSCs towards the center of the wound compared to the control cells. In conclusion, soluble factor pretreated MSCs with altered mechanical properties displayed significantly improved cell functions leading to highly efficient tissue regeneration in vivo. Mechanical priming of MSCs with niche specific factors prior to transplantation can become a viable strategy to maximize their therapeutic potential.
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Books on the topic "Soluble factor"

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Alharbi, Yousef, Manish S. Patankar, and Rebecca J. Whelan. Antibody-Based Therapy for Ovarian Cancer. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190248208.003.0006.

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With their role in connecting disease-associated antigens to the cellular immune response, antibodies hold considerable promise as therapeutic agents. This chapter discusses three classes of therapeutic antibodies that have been developed for use in ovarian cancer therapy. The first includes antibodies selected against tumor-associated antigens such as MUC16/CA125, mesothelin, epithelial cell adhesion molecule, and folate receptor α‎. Antibodies in the second class target proteins such as CTLA-4 and PD1 that act as immune response checkpoint receptors. The third class of antibodies target secreted factors that promote tumor growth: targets in this class include vascular endothelial growth factor, cytokines, and chemokines. The development of each of these is described. The chapter also discusses the complications presented by soluble antigens, which serve to limit the applicability of antigens (such as MUC16/CA125) that are both cell-surface associated and circulating and the prospects for the combination of antibody-based immunotherapy and chemotherapy.
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Alfano, Massimo, ed. Soluble Factors Mediating Innate Immune Responses to HIV Infection. BENTHAM SCIENCE PUBLISHERS, 2012. http://dx.doi.org/10.2174/97816080500621100101.

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Isaacs, John D., and Philip M. Brown. Rituximab and abatacept. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0083.

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Two biologics that target cells have been licensed to treat rheumatoid arthritis (RA). Rituximab is a chimeric monoclonal antibody (mAb) against CD20 that depletes B cells; abatacept is a soluble form of CTLA-4 that blocks costimulation and interferes with T-cell function. Both drugs alleviate signs and symptoms of RA and have been shown to retard radiographic progression. Rituximab is licensed for use following failure of tumour necrosis factor (TNF) blockade whereas abatacept's licence permits it use as a first-line biologic. In the United Kingdom, however, the National Institute for Health and Clinical Excellence (NICE) restricts the use of abatacept to patients who develop adverse effects with rituximab or in whom rituximab is contraindicated. As with other biologics, the use of either drug is associated with an enhanced risk of serious infections; additionally, rituximab in particular can cause infusion reactions, requiring prophylaxis. By targeting cells that are central to RA pathogenesis, these drugs provide important additional therapeutic options for patients with RA.
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Badimon, Lina, Felix C. Tanner, Giovanni G. Camici, and Gemma Vilahur. Pathophysiology of thrombosis. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198755777.003.0018.

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Ischaemic heart disease and stroke are major causes of death and morbidity worldwide. Coronary and cerebrovascular events are mainly a consequence of a sudden thrombotic occlusion of the vessel lumen. Arterial thrombosis usually develops on top of a disrupted atherosclerotic plaque because of the exposure of thrombogenic material, such as collagen fibrils and tissue factor (TF), to the flowing blood. TF, either expressed by subendothelial cells, macrophage- and/or vascular smooth muscle-derived foam-cells in atherosclerotic plaques, is a key element in the initiation of thrombosis due to its ability to induce thrombin formation (a potent platelet agonist) and subsequent fibrin deposition at sites of vascular injury. Adhered platelets at the site of injury also play a crucial role in the pathophysiology of atherothrombosis. Platelet surface receptors (mainly glycoproteins) interact with vascular structures and/or Von Willebrand factor triggering platelet activation signalling events, including an increase in intracellular free Ca2+, exposure of a pro-coagulant surface, and secretion of platelet granule content. On top of this, interaction between soluble agonists and platelet G-coupled protein receptors further amplifies the platelet activation response favouring integrin alpha(IIb)beta(3) activation, an essential step for platelet aggregation. Blood-borne TF and microparticles have also been shown to contribute to thrombus formation and propagation. As thrombus evolves different circulating cells (red-blood cells and leukocytes, along with occasional undifferentiated cells) get recruited in a timely dependent manner to the growing thrombus and further entrapped by the formation of a fibrin mesh.
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Marchetta, Anthony R. Role of soluble factors in the enhanced tumor resistance in protein-malnourished mice. 1997.

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Erwin, William Mark. A study of canine notochord cell-derived soluble factors that enhance proteoglycan production by intervertebral disc chondrocytes. 2004.

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Parkhomenko, Yu M., and G. V. Donchenko. Vitamins in Human Health. PH “Akademperiodyka”, 2006. http://dx.doi.org/10.15407/akademperiodyka.063.182.

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The book describes the history of the discovery of vitamins, presents modern ideas about the properties of vitamins and their importance for humans as essential nutritional factors. General information is provided about the modern classification of vitamins, physicochemical and biological properties of water- and fat-soluble vitamins and vitamin-like compounds, their role in metabolism and, in general, in human health. The causes of hypovitaminosis are analyzed, advice is given on their prevention and storage of vitamins in food. The book is intended for specialists in the field of biology, medicine, as well as for a wide range of readers, including teachers, students and other people interested in health issues.
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Ronco, Claudio, and William R. Clark. Haemodialysis. Edited by Jonathan Himmelfarb. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0257.

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End-stage renal disease (ESRD) is common clinical condition for which life-sustaining therapies fortunately exist. On a global basis, more than 2 million patients now receive chronic haemodialysis (HD) for treatment of ESRD. For the vast majority of these patients, treatment is provided in a dialysis unit on a thrice-weekly basis, although there is growing interest in alternative therapies which vary with respect to location or frequency. Based on the number of patients requiring chronic HD now and in the foreseeable future, it is imperative that nephrologists understand the basic principles underlying this treatment. The factors affecting the delivery of therapy in HD can substantially be divided into two groups: (a) factors affecting the performance of the dialytic technique, which are primarily related to the characteristics of the parameters involved in the dialytic technique; and (b) factors affecting the clinical results of a given technique, which are primarily related to the interaction between the water and solute removal capacity of the technique and the kinetics of water and solutes within the human body. In this group, factors including staff compliance with the orders, patient compliance with prescribed time, and the patient’s physical condition are also important.The focus of this chapter is the technical aspects of chronic HD prescription and delivery. After a brief review of the major components of the HD system (machine and extracorporeal circuit), the principles underlying solute and water removal are reviewed. The concept of clearance is then assessed, with particular emphasis on the determinants of small solute clearance with respect both to the dialyser and the patient.
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Bhole, Malini. Functions of the immune system. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0293.

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This chapter reviews the functions of the immune system, which has evolved to provide a defence mechanism against microbial challenges, and is divided into two main branches, innate and adaptive. In addition, there are physical and chemical barriers, including skin, mucous membrane, mucous secretions, saliva, and various enzymes, and these contribute to the first line of defence against pathogens. The innate immune system provides the initial quick response for rapid recognition and elimination of pathogens, as opposed to the adaptive immune system, which has evolved to provide a more definitive and finely tuned response. The common central feature of both of these systems is the ability to distinguish between self and non-self. The recognition of non-self or ‘foreign’ pathogens and the subsequent immune response is orchestrated by a whole range of cells and soluble (humoral) factors in both innate and adaptive immune systems.
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Daudon, Michel, and Paul Jungers. Uric acid stones. Edited by Mark E. De Broe. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0202_update_001.

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Uric acid (UA) stones are typically red-orange and often appear as sand/ gravel though they may be large. They are totally radiolucent. They account for about 10% of all kidney stones in most countries, and up to 20% in some populations. It is twice as frequent in males, prevalence increases with age, and it is two to three times higher in patients with type 2 diabetes or with features of the metabolic syndrome. Factors that induce the formation of UA stones are a low urine volume, hyperuricosuria, and, more importantly, a permanently low urine pH (< 5). Indeed, below its pKa of 5.35 at 37°C, UA is in non-dissociated form, whose solubility is at best 100 mg/L, whereas urinary UA excretion normally exceeds 600 mg/day and may exceed 1g/day.Because UA solubility increases up to approximately 500 mg/L at urine pH > 6, urine alkalinization, with a target pH of 6.5–7, is the cornerstone of medical treatment. This most often allows dissolution of existing stones and prevention of recurrent stone formation so that urological intervention is infrequently needed. The preferred agent for alkalinization is potassium citrate (30–60 mEq/day in divided doses), because potassium urate is twice more soluble than sodium urate. However, in patients with poor gastric tolerance to potassium citrate or contraindication to potassium supplements, sodium bicarbonate is an acceptable alternative. Limitation of animal proteins, purine-rich foods (including beer), alcoholic drinks and acidified beverages (sodas) are useful measures, together with large fluid intake (> 2–2.5 L/day). Allopurinol may be indicated in cases of symptomatic hyperuricaemia. Regular observance of alkalinisation, with periodic controls of urine pH by the patient, is needed to prevent the rapid formation of UA stones. Patients affected by UANL, especially if overweight, should be evaluated for type 2 diabetes or glucose intolerance and managed accordingly.
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Book chapters on the topic "Soluble factor"

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Howard, Maureen. "Soluble-Factor Induction of B-Cell Growth." In The Interleukins, 181–93. Boston, MA: Springer US, 1985. http://dx.doi.org/10.1007/978-1-4684-4838-2_7.

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Engelmann, H., D. Aderka, Y. Nophar, O. Kemper, C. Brakebusch, H. Holtmann, and D. Wallach. "Soluble and cell surface receptors for tumor necrosis factor." In Mononuclear Phagocytes, 359–65. Dordrecht: Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-015-8070-0_48.

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Engelmann, H., D. Aderka, Y. Nophar, O. Kemper, C. Brakebusch, H. Holtmann, and D. Wallach. "Soluble and Cell Surface Receptors for Tumor Necrosis Factor." In Host Defense Dysfunction in Trauma, Shock and Sepsis, 599–607. Berlin, Heidelberg: Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-77405-8_76.

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Baron, Andre T., Jacqueline M. Lafky, Cecelia H. Boardman, Elsa M. Cora, Marites C. Buenafe, Dachao Liu, Alfred Rademaker, et al. "Soluble Epidermal Growth Factor Receptor: A Biomarker of Epithelial Ovarian Cancer." In Cancer Treatment and Research, 189–202. Boston, MA: Springer US, 2009. http://dx.doi.org/10.1007/978-0-387-98094-2_9.

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Bandyopadhyay, Abhik, and LuZhe Sun. "Soluble TGF-β Type III Receptor Suppresses Malignant Progression of Human Cancer Cells." In Transforming Growth Factor-β in Cancer Therapy, Volume II, 723–35. Totowa, NJ: Humana Press, 2008. http://dx.doi.org/10.1007/978-1-59745-293-9_44.

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Evans, Elizabeth S., Erik D. Hanson, and Claudio L. Battaglini. "Immune, Endocrine, and Soluble Factor Interactions During Aerobic Exercise in Cancer Survivors." In Endocrinology of Physical Activity and Sport, 441–58. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-33376-8_24.

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Romero, Xavier, Juan D. Cañete, and Pablo Engel. "Determination of Soluble Tumor Necrosis Factor Receptor 2 Produced by Alternative Splicing." In Methods in Molecular Biology, 187–99. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-0669-7_16.

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Suzuki, Eiji, and Steven M. Albelda. "Soluble Type II Transforming Growth Factor-β Receptor Inhibits Tumorigenesis by Augmenting Host Antitumor Immunity." In Transforming Growth Factor-β in Cancer Therapy, Volume II, 697–706. Totowa, NJ: Humana Press, 2008. http://dx.doi.org/10.1007/978-1-59745-293-9_42.

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Evans, Elizabeth S., and Claudio L. Battaglini. "Oncology Patients and Aerobic Exercise: Immune System, Endocrine System, and Soluble Factor Responses." In Endocrinology of Physical Activity and Sport, 461–500. Totowa, NJ: Humana Press, 2013. http://dx.doi.org/10.1007/978-1-62703-314-5_24.

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Ozgurtas, T. "Breast milk soluble vascular endothelial growth factor receptor-1 and implications for health." In Handbook of dietary and nutritional aspects of human breast milk, 437–46. The Netherlands: Wageningen Academic Publishers, 2013. http://dx.doi.org/10.3920/978-90-8686-764-6_24.

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Conference papers on the topic "Soluble factor"

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de Trad, Chafia Hejase. "Soluble CD40L Versus Myocyte Enhancer Factor: Predicting a Prominent Marker For Cardiovascular Disease." In Conference Proceedings. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 2006. http://dx.doi.org/10.1109/iembs.2006.260240.

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de Trad, Chafia Hejase. "Soluble CD40L Versus Myocyte Enhancer Factor: Predicting a Prominent Marker For Cardiovascular Disease." In Conference Proceedings. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 2006. http://dx.doi.org/10.1109/iembs.2006.4397748.

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Patil, Pratima, Robert W. Mason, Julia D' Ambrosio, and Ayyappan K. Rajasekaran. "Abstract LB-032: Soluble E-cadherin as a microenvironmental factor that enhances tumor progression." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-lb-032.

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Bitzer, A., A. Laber, E. Gadermaier, J. Wallwitz, G. Berg, and G. Himmler. "Sandwich ELISA for the Quantification of Soluble Human Semaphorin 4D, a factor promoting skeletal metastases." In OSTEOLOGIE 2019. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1679968.

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Rego, Stephen, Krista Ricci, Muthulekha Swamydas, and Didier Dreau. "Abstract 397: Soluble Tumor Necrosis Factor Receptor shed by breast tumor cells modulates macrophage migration." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-397.

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Epstein Shochet, Gali, Becky Bardenstein-Wald, Elizabetha Brook, and David Shitrit. "Transforming growth factor beta (TGF-ß) pathway activation by IPF fibroblast-derived soluble factors is mediated by IL-6 trans-signaling." In ERS International Congress 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/13993003.congress-2020.3352.

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Gonzalez-Ferrer, S., T. Olonisakin, D. Van Tyne, and J. Lee. "A Pathogen-Encoded Soluble Factor Regulates Heme-Mediated Macrophage Suppression of STAT1 During Klebsiella Pneumoniae Infection." In American Thoracic Society 2021 International Conference, May 14-19, 2021 - San Diego, CA. American Thoracic Society, 2021. http://dx.doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1253.

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Zakrzewicz, A., K. Siebers, S. Wilker, K. Richter, R. Tikkanen, W. Padberg, S. Janciauskiene, and V. Grau. "SLPI inhibits ATP-mediated maturation of IL-1β from human monocytes via release of a soluble factor." In Herbsttagung der Sektionen Zellbiologie und Infektiologie und Tuberkulose der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin e.V. Georg Thieme Verlag KG, 2018. http://dx.doi.org/10.1055/s-0037-1615312.

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Chen, Fei, Da Fu, Eric Lam, and Yu Sun. "Abstract 2972: SPINK1, a soluble factor released by the therapy-damaged tumor microenvironment, promotes prostate cancer resistance." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-2972.

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Jaffar, Jade, Xiahui Tan, Judith L. Black, Brian G. Oliver, W. S. Argraves, Waleed O. Twal, and Janette K. Burgess. "The Release Of Soluble Fibulin-1 From Airway Epithelial Cells Is Increased By Transforming Growth Factor Beta." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a6684.

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Reports on the topic "Soluble factor"

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Park, Jong-In. Identification of a Soluble Factor that Induces Cell Death and Growth Inhibition in Prostate Carcinoma Cells. Fort Belvoir, VA: Defense Technical Information Center, February 2010. http://dx.doi.org/10.21236/ada524479.

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Baulch, Janet. Identification and Characterization of Soluble Factors Involved in Delayed Effects of Low Dose Radiation. Final report. Office of Scientific and Technical Information (OSTI), September 2013. http://dx.doi.org/10.2172/1092411.

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