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Dissertations / Theses on the topic 'Solute carrier family 2'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

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1

Lohi, Hannes. "The human solute carrier 26 family of anion exchangers." Helsinki : University of Helsinki, 2002. http://ethesis.helsinki.fi/julkaisut/laa/haart/vk/lohi/.

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2

Graf, Justin T. "Membrane associated transporter protein gene (SLC45A2) and the genetic basis of normal human pigmentation variation." Thesis, Queensland University of Technology, 2008. https://eprints.qut.edu.au/25913/1/Justin_Graf_Thesis.pdf.

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This work is concerned with the genetic basis of normal human pigmentation variation. Specifically, the role of polymorphisms within the solute carrier family 45 member 2 (SLC45A2 or membrane associated transporter protein; MATP) gene were investigated with respect to variation in hair, skin and eye colour ― both between and within populations. SLC45A2 is an important regulator of melanin production and mutations in the gene underly the most recently identified form of oculocutaneous albinism. There is evidence to suggest that non-synonymous polymorphisms in SLC45A2 are associated with normal

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3

Graf, Justin T. "Membrane associated transporter protein gene (SLC45A2) and the genetic basis of normal human pigmentation variation." Queensland University of Technology, 2008. http://eprints.qut.edu.au/25913/.

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This work is concerned with the genetic basis of normal human pigmentation variation. Specifically, the role of polymorphisms within the solute carrier family 45 member 2 (SLC45A2 or membrane associated transporter protein; MATP) gene were investigated with respect to variation in hair, skin and eye colour ― both between and within populations. SLC45A2 is an important regulator of melanin production and mutations in the gene underly the most recently identified form of oculocutaneous albinism. There is evidence to suggest that non-synonymous polymorphisms in SLC45A2 are associated with normal

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4

Keathley, Russell Hudson. "Exploring Structure and Function Relationships of the Solute Carrier Protein Family in Disease." Thesis, Icahn School of Medicine at Mount Sinai, 2018. http://pqdtopen.proquest.com/#viewpdf?dispub=10931576.

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<p> The solute carrier family (“SLC”) is a diverse group of membrane transporter proteins expressed ubiquitously throughout the human body. SLC members have been heavily implicated in Mendelian disease, and play an active role in the pathogenesis of many cancers. Further, several members of the SLC family have ligands and/or precise functions that have yet to be elucidated. As such, examining the structure and function relationships of this family can have significant implication in the study and drug design of serious disease. We explored these structure and function relationships

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5

Sibthorpe, Dean. "Molecular evolution of the solute carrier family 11 (SLC11) protein in the Pufferfish, Fugu rubripes." Thesis, University of Cambridge, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.398868.

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6

Zaahl, Monique G. (Monique Glenda). "Mutational analysis of the solute carrier family 11 member 1 gene (SLC11A1) implicated in iron transport." Thesis, Stellenbosch : Stellenbosch University, 2003. http://hdl.handle.net/10019.1/53510.

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Thesis (PhD)--University of Stellenbosch, 2003.<br>ENGLISH ABSTRACT: The solute carrier family 11 member 1 gene (SLC11A 1) is a divalent metal ion transporter with various pleiotropic effects on macrophage function. This gene that regulates iron, and is also regulated by cellular iron levels, has previously been linked to many infectious and autoimmune diseases. In this analysis, in vitro studies using the luciferase reporter system as well as case-control association studies were applied to investigate the significance of SLC11 A1 allelic variation in patients with diverse disease phen

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7

Bowen, Holly. "Characterisation of the solute carrier family member 11al (Slc11al) promoter : regulation by c-Myc and miz-1." Thesis, University of Southampton, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.274540.

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8

Hellsten, Sofie Victoria. "Characterization of Amino Acid Transporters : Transporters expressed in the central nervous system belonging to the Solute Carrier family SLC38." Doctoral thesis, Uppsala universitet, Institutionen för neurovetenskap, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-275723.

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In cells and organelles transporters are responsible for translocation of amino acids, sugars and nucleotides among others. In the central nervous system (CNS), amino acid transporters can function as neurotransmitter transporters and nutrient sensors. The Solute carrier (SLC) superfamily is the largest family of transporters with 395 members divided in 52 families. The system A and system N amino acid transporter family, SLC38, consists of 11 members, SNAT1-11 (SLC38A1-11). The members are expressed in the brain, exclusively in neurons or astrocytes and some in both. Amino acid signaling is m

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9

McManus, Kirk James. "Molecular variation in the solute carrier family 4, anion exchanger member 1 gene, characterization of three low-incidence erythroid antigens." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/MQ51766.pdf.

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10

柿崎, 文彦. "Caudal-related homeobox(CDX)の新規標的遺伝子 Solute Carrier Family 5, Member 8(SLC5A8)の同定". 京都大学 (Kyoto University), 2010. http://hdl.handle.net/2433/120360.

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11

Maddox, Katherine. "A characterization of the calcium- and integrin-binding protein family." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 112 p, 2009. http://proquest.umi.com/pqdweb?did=1654487501&sid=7&Fmt=2&clientId=8331&RQT=309&VName=PQD.

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12

Kepenek, Eda Seyma. "Polymorphism Of Prolactin (prl), Diacylglycerol Acyltransferase (dgat-1) And Bovine Solute Carrier Family 35 Member 3 (slc35a3) Genes In Native Cattle Breeds And Its Implication For Turkish Cattle Breeding." Master's thesis, METU, 2008. http://etd.lib.metu.edu.tr/upload/12609121/index.pdf.

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In the present study samples from four native Turkish Cattle Breeds<br>South Anatolian Red (n= 48), East Anatolian Red (n= 34), Anatolian Black (n= 42) and Turkish Grey (n=46) and elite bulls of Holstein (n=21) were genotyped with respect to two milk production enhancer genes, Prolactin (PRL) and Diacylglycerol acyltransferase (DGAT1), and one disease (Complex Vertebral Malformation) causing gene (SLC35A3). A allele frequency for PRL gene, believed to be positively associated with the milk yield in cattle, ranged between 0.5645 (Anatolian Black) - 0.7558 (South Anatolian Red). K allele frequen

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13

Brenner, Christiane. "Dissecting peptidoglycan trafficking and transport(ers) in human cells." Thesis, Sorbonne Paris Cité, 2018. http://www.theses.fr/2018USPCB240.

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Les fragments du peptidoglycane, les muropeptides muramyl-triDAP (MTP) et le muramyl dipeptide (MDP) sont détectés spécifiquement par les récepteurs cytosoliques du système immunitaire inné, Nod1 et Nod2, respectivement. Mais à ce jour, l’internalisation cellulaire de ces fragments, et plus particulièrement dans les cellules du colon humain, reste mal connue. Dans le but de mieux comprendre ce processus d’internalisation cellulaire, une lignée de cellules humaines du colon HT-29 a été utilisée comme modèle. Les deux récepteurs, Nod1 et Nod2 ont été décrits comme étant exprimés dans cette ligné

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14

Hui, Daniel Jason. "The Mechanism of Protein Synthesis Inhibition by the P56 Family of Viral Stress Inducible Proteins." Connect to text online, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=case1104848977.

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15

Dallas, Shannon, Michelle Block, Deborah Thompson, et al. "Microglial activation decreases retention of the protease inhibitor saquinavir: implications for HIV treatment." BioMed Central, 2013. http://hdl.handle.net/10150/610193.

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BACKGROUND:Active HIV infection within the central nervous system (CNS) is confined primarily to microglia. The glial cell compartment acts as a viral reservoir behind the blood-brain barrier. It provides an additional roadblock to effective pharmacological treatment via expression of multiple drug efflux transporters, including P-glycoprotein. HIV/AIDS patients frequently suffer bacterial and viral co-infections, leading to deregulation of glial cell function and release of pro-inflammatory mediators including cytokines, chemokines, and nitric oxide.METHODS:To better define the role of inflam

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16

Tall, Renee Danielle. "Intracellular trafficking of influenza hemagglutinin and members of the low density lipoprotein receptor family." 2004. http://edissertations.library.swmed.edu/pdf/TallR121504/TallRenee.pdf.

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17

Millé, Aline Noel. "Einfluss des Transkriptionsfaktors B-cell lymphoma 6 (BCL6) auf die Expression renaler Transportproteine." Doctoral thesis, 2016. http://hdl.handle.net/11858/00-1735-0000-002B-7C49-1.

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