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Dissertations / Theses on the topic 'Solvent evaporation method'

Author: Grafiati
Published: 3 June 2025
Last updated: 1 August 2025

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1

Mohamed, Hajjah Farahidah. "Formulation and evaluation of polyester microspheres by solvent-evaporation method." Thesis, University of Strathclyde, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.488758.

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2

Patlolla, Karthik Reddy. "Predicting aqueous solubility of pharmaceutical agents by solid dispersion prepared by solvent evaporation method." Scholarly Commons, 2015. https://scholarlycommons.pacific.edu/uop_etds/268.

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Solubility of active pharmaceutical agents is a crucial process that determines drug absorption and ultimately its bioavailability. Many of the new therapeutically beneficial compounds discovered are lipophilic requiring various solubility enhancement strategies to improve their solubility. Among these strategies, solubility enhancement using solid dispersions is a leading method. To obtain a desirable increase in the solubility of a poorly-soluble compound, a good understanding of the molecular descriptors influencing the enhancement of solubility is essential. Therefore, the major research o
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3

[Verfasser], Muhaimin. "Study of microparticle preparation by the solvent evaporation method using focused beam reflectance measurement (FBRM) / Muhaimin." Berlin : Freie Universität Berlin, 2013. http://d-nb.info/1044294272/34.

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4

Nabar, Gauri M. "Encapsulation of nanoparticles and polymers within block copolymer micelles prepared by the emulsion and solvent evaporation method." The Ohio State University, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=osu1503199514997833.

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5

Nastiti, Christofori Maria Ratna Rini. "Development and evaluation of polymeric nanoparticle formulations for triamcinolone acetonide delivery." Thesis, Curtin University, 2007. http://hdl.handle.net/20.500.11937/613.

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The aims of this study were to develop polymeric NP formulations for triamcinolone acetonide (TA) delivery, from biodegradable and biocompatible hydrophobic polymers, which provide sustained release, prolonged stability and low toxicity, and to assess the toxicity of TA NPs (TA-NPs) compared to TA alone upon BALB/c 3T3 and ARPE 19 cell culture models.The study involved investigation of three different types of polymers: poly(D,L,lactide) (PDLLA), poly(D,L,lactide-co-glycolide)(PLGA) and methoxypolyethyleneglycol poly(D,L,lactide-co-glycolide)(mPEG PLGA). Two different methods were studied in t
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6

Wu, Giin-Wen, and 吳錦文. "Conurolled Release Drug Microcapsules Prepared by Emulsion Solvent Evaporation Method." Thesis, 1996. http://ndltd.ncl.edu.tw/handle/68030634689056097526.

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碩士<br>國立成功大學<br>化學工程學系<br>84<br>The emulsion solvent evaporation method was used to prepare controlled rele-ase formation of drugs in this report. The microcapsules of controlled relea-se was formed by polymer solution (Ethylcellulose) containing drug (Aspirin). There were six variables, including the addition nonsolvent volume in coat-ing solution, the different polymer concertration, the different ratio of drugto shell , the different ratio of dispersion medium volume to solvent volu
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Sun, Wei-Zhe, and 孫偉哲. "Development of Lansoprazole Sustained-Release Microparticles Using Solvent Evaporation Method." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/89328606200515275042.

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碩士<br>國立臺灣大學<br>藥學研究所<br>96<br>Lansoprazole is a proton pump inhibitor which selectively inhibits H+/K+-ATPase. It is usually used for gastric ulcer diseases. However, due to its short half life in plasma, lansoprazole cannot control nocturnal acid breakthrough. This study was aimed to improve this situation by preparing sustained-release lansoprazole microparticles. In this study, the RS-100 sustained release microparticles were made by the oil/water solvent evaporation method. Three responses (homogenization rate, concentration of Eudragit®® RS-100 and Eudragit®® RS-100/lansoprazole ratio) t
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8

Huang, Li Ine, and 黃莉英. "The studies on protein - loaded poly(e - caprolactone) microparticles prepared by solvent evaporation method." Thesis, 1999. http://ndltd.ncl.edu.tw/handle/69587580387754914975.

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碩士<br>國立臺灣大學<br>藥學研究所<br>87<br>Microencapsulation of proteins and peptides for preparation of sustained release dosage forms is being widely investigated as a means of improving the therapeutic efficiency of these bioactive materials. Biodegradable polymers, poly(e-caprolactone) (PCL), exhibited certain desirable characteristics for drug delivery applications, which included the ideal mechanical properties, tissue compatibility, commercial available and ease of processing. The purpose of this study was to demonstrate the characteristics of bovine serum albumin (BSA) loaded PCL microparticles.
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9

Chang, Chia-Ju, and 張加儒. "Microencapsulation of epoxy curing agent by oil-in-water emulsion and solvent evaporation method." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/zc29pu.

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碩士<br>國立臺灣大學<br>高分子科學與工程學研究所<br>106<br>Although epoxy resins have excellent mechanical and chemical properties, epoxy resins and curing agent are generally stored in two pots to prevent unnecessary curing reaction at room temperature. To solve this problem, we developed a one pot system which can be stored for a long time at room temperature by a simple, nontoxic processing. This involves the encapsulation of the curing agent, 2-phenylimidazole (2PhI), in polycaprolactone (PCL) microcapsules fabricated by oil-in-water emulsion and solvent evaporation method with different organic solvents and
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10

Chang, Liling, and 張麗玲. "Studies on the preparation of ethylcellulose microcapsules by using o/w emulsion solvent evaporation method." Thesis, 1998. http://ndltd.ncl.edu.tw/handle/20176669638720178853.

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碩士<br>國立中央大學<br>化學工程學系<br>86<br>The microcapsules containing water-soluble drug prepared by using O/Wemulsion solvent evaporation method in order to reduce the additiond ofsolvent wrer developed. Microencapsulation condition, system temperature,polymer concentration, co-solvent on drug loss, particle size, surface morphology and release rate of microcapsules were disscussed.
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11

Wu, Tzone-Lin, and 吳宗霖. "The Stability of Fenoterol HBr in Aqueous Solutions and the Preparation of Microspheres by Solvent Evaporation Method." Thesis, 1998. http://ndltd.ncl.edu.tw/handle/51518572829365117168.

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碩士<br>國立臺灣大學<br>藥學系<br>86<br>Fenoterol HBr為一b2作用劑，因對支氣管具有選擇性，不易有全 身性副作用，所以常用來治療及預防支氣管氣喘。常用的投予方式 為口服及吸入法。 藥物的安定與否，會影響其生體可用率及藥物的經濟價值，所以 對fenoterol HBr水溶液的安定性作一深入探討，利用高壓液相層析 法分析，來得知溫度、緩衝溶液濃度、離子強度、溶液pH值及光線 對藥物的影響。Fenoterol HBr之分解近似擬似一級反應動力學，經 由60蚓、70蚓、80蚓三個溫度所求得之活化能，介於12.2~38.2 之間。Fenoterol HBr在鹼性環境下比在酸性環境下容易分解，在pH > 5.59時，隨著pH值的增加而快速增加，在3.46 < pH <5.59則與 pH值較不相關，隨pH上升只有微量下降，1.61 < pH < 3.46時，反 應速率與pH呈正相關，在0.37 < pH < 1.61時，則隨著pH的上升，
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12

Pei-Yu, Chen, and 陳佩俞. "The preparation and the kinetic study of microcapsules by using o/w emulsion evaporation method in the presence of different co-solvent." Thesis, 1999. http://ndltd.ncl.edu.tw/handle/04823414321971421946.

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碩士<br>國立中央大學<br>化學工程研究所<br>87<br>In this work, the water-soluble drug microcapsules with zero-order released beheavior and different released rate based on TH and EC in the presence of different co-solvent, mostly alcohol or alkane, were developed by o/w emulsion solvent evaporation method. The theophylline, ethylcellulose, dichloromethane, polyvinyl alcohol and tween 60 were chosen as the core material, wall material, solvent, stabilizer and surfactant, respectively. The experimental results show that the use of different co-solvent for the preparation of microcapsules resulted in
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13

Voldřichová, Lenka. "Lipidické nanočástice jako platforma pro dodání léčiv." Master's thesis, 2020. http://www.nusl.cz/ntk/nusl-411759.

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Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of: Pharmaceutical Technology Supervisor: PharmDr. Ondřej Holas, Ph.D. Consultant: Mgr. Jana Kubačková Student: Lenka Voldřichová Title of thesis: Lipid based nanoparticles: drug delivery platform Lipic nanoparticles, as newly developed dosage forms, can overcome many drawbacks of conventional dosage forms. Their potential can be utilized in particular for prolonged, controlled and targeted release. They can also increase the bioavailability of drugs, especially those with poor solubility and also allow targeting, w
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14

Sarkar, Ranajoy. "Formulation and evaluation of an artificial lipoprotein gene delivery system for targeted gene delivery to glioma cells ; effect of dual surfactant systems on properties of ethyl cellulose microspheres prepared by non-aqueous emulsion-solvent evaporation method." 2005. http://purl.galileo.usg.edu/uga%5Fetd/sarkar%5Franajoy%5F200505%5Fphd.

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Thesis (Ph. D.)--University of Georgia, 2005.<br>Directed by James C. Price. Chapter 2 published in Biomedical aspects of drug targeting. Includes articles submitted to Pharmaceutical research, Journal of microencapsulation, and International journal of pharmaceutics. Includes bibliographical references.
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15

Lai, Mei-Kuan, and 賴美冠. "Application of Different Emulsion Solvent-evaporation Methods and Gold Nanoparticles to Microencapsulation." Thesis, 2006. http://ndltd.ncl.edu.tw/handle/76961150644841642893.

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博士<br>國立中正大學<br>化學工程所<br>94<br>The first section of paper describes the microencapsulation of acetaminophen (APAP) in poly(L-lactide) (PLLA) via the oil-in-water emulsification solvent-evaporation method. The thermogravimetric analysis and differential scanning calorimetry data indicated that the acetaminophen was encapsulated and uniformly distributed in the poly(L-lactide) microcapsules. The addition of either gelatin or polyvinyl alcohol as the protective colloid to the emulsion was found to have a significant impact on the resulting microcapsules. Increasing the concentration of either
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