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Journal articles on the topic 'Somal'

Author: Grafiati

Published: 4 June 2021

Last updated: 10 February 2022

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1

Matthews, B. F., and R. A. Matthews. "The tegument in Hemiuridae (Digenea: Hemiuroidea): structure and function in the adult." Journal of Helminthology 62, no. 4 (1988): 305–16. http://dx.doi.org/10.1017/s0022149x00011718.

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AbstractThe teleost stomach, as a site of strong acid proteolytic digestion at pH 1–4, is a hostile environment rarely chosen as a habitat by parasites. Several Hemiuroidea have nevertheless invaded this niche, notably the Hemiuridae, a family in which the body is characterized by a retractile “tail”, or ecsoma. The structure and function of the latter has been studied in three hemiurid species, namely Hemiurus communis, Lecithochirium rufoviride and L. fusiforme, using ultrastructural, histochemical and autoradiographic techniques. Results indicate a clear demarcation between the function of

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2

Ritter, A. M., and L. M. Mendell. "Somal membrane properties of physiologically identified sensory neurons in the rat: effects of nerve growth factor." Journal of Neurophysiology 68, no. 6 (1992): 2033–41. http://dx.doi.org/10.1152/jn.1992.68.6.2033.

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1. Intracellular recordings were made in situ from physiologically identified dorsal root ganglion (DRG) cells in untreated rats aged 5-8 wk and in rats treated from birth to 5 wk of age with nerve growth factor (NGF) or antisera against NGF (anti-NGF). 2. As demonstrated in cats, the shape of the somal action potential (AP) of DRG cells of normal rats is correlated with peripheral receptor type. Cells that innervate high-threshold mechanoreceptors (HTMRs) and thus respond to noxious stimulation of skin or deep tissue in the periphery have long-duration APs characterized by an inflection on th

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3

Zahratka, Jeffrey A., Paul D. E. Williams, Philip J. Summers, Richard W. Komuniecki, and Bruce A. Bamber. "Serotonin differentially modulates Ca2+ transients and depolarization in a C. elegans nociceptor." Journal of Neurophysiology 113, no. 4 (2015): 1041–50. http://dx.doi.org/10.1152/jn.00665.2014.

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Monoamines and neuropeptides modulate neuronal excitability and synaptic strengths, shaping circuit activity to optimize behavioral output. In C. elegans, a pair of bipolar polymodal nociceptors, the ASHs, sense 1-octanol to initiate escape responses. In the present study, 1-octanol stimulated large increases in ASH Ca2+, mediated by L-type voltage-gated Ca2+ channels (VGCCs) in the cell soma and L-plus P/Q-type VGCCs in the axon, which were further amplified by Ca2+ released from intracellular stores. Importantly, 1-octanol-dependent aversive responses were not inhibited by reducing ASH L-VGC

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4

Tompkins, Margaret M., and William D. Hill. "Contribution of somal Lewy bodies to neuronal death." Brain Research 775, no. 1-2 (1997): 24–29. http://dx.doi.org/10.1016/s0006-8993(97)00874-3.

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5

Rose, R. D., and W. J. Karnavas. "Neural nets identify sensory receptors from somal spikes." Brain Research 630, no. 1-2 (1993): 345–48. http://dx.doi.org/10.1016/0006-8993(93)90676-e.

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6

Pierri, Joseph N., Christine L. E. Volk, Sungyoung Auh, Allan Sampson, and David A. Lewis. "Somal size of prefrontal cortical pyramidal neurons in schizophrenia." Biological Psychiatry 54, no. 2 (2003): 111–20. http://dx.doi.org/10.1016/s0006-3223(03)00294-4.

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7

Rajkowska, Grazyna, Lynn D. Selemon, and Patricia S. Goldman-Rakic. "Neuronal and Glial Somal Size in the Prefrontal Cortex." Archives of General Psychiatry 55, no. 3 (1998): 215. http://dx.doi.org/10.1001/archpsyc.55.3.215.

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8

Rose, R. D., H. R. Koerber, M. J. Sedivec, and L. M. Mendell. "Somal action potential duration differs in identified primary afferents." Neuroscience Letters 63, no. 3 (1986): 259–64. http://dx.doi.org/10.1016/0304-3940(86)90366-6.

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9

Hosseinisharifabad, M., and J. R. Nyengaard. "Normal distributions of somal volume estimates in rat hippocampus." International Journal of Psychophysiology 69, no. 3 (2008): 241. http://dx.doi.org/10.1016/j.ijpsycho.2008.05.557.

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10

Ritter, Amy M., C. Jeffery Woodbury, Kathryn Albers, Brian M. Davis, and H. Richard Koerber. "Maturation of Cutaneous Sensory Neurons From Normal and NGF-Overexpressing Mice." Journal of Neurophysiology 83, no. 3 (2000): 1722–32. http://dx.doi.org/10.1152/jn.2000.83.3.1722.

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In the rodent, cutaneous sensory neurons mature over the first two postnatal weeks, both in terms of their electrical properties and their responses to mechanical stimulation of the skin. To examine the coincidence of these events, intracellular recordings were made from neurons in the dorsal root ganglion (DRG) in an in vitro spinal cord, DRG, and skin preparation from mice between the ages of postnatal day 0 and 5 ( P0–P5). We also examined mice in which nerve growth factor (NGF) is overexpressed in the skin. NGF has been shown to be involved in a number of aspects of sensory neuron developm

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11

Zhao, Shifang, Wenqiang Fan, Xiang Guo, et al. "Microenvironments to study migration and somal translocation in cortical neurons." Biomaterials 156 (February 2018): 238–47. http://dx.doi.org/10.1016/j.biomaterials.2017.11.042.

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12

Böhrer, H., H. Schmidt, T. Augenstein, A. Bach, and E. Martin. "INHIBITION OF HEPATIC MICRO-SOMAL DRUG METABOLISM BY ATRACURIUM ADMINISTRATION." Anesthesiology 75, no. 3 (1991): A356. http://dx.doi.org/10.1097/00000542-199109001-00356.

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13

Matthews, B. F., and R. A. Matthews. "The ecsoma in Hemiuridae (Digenea: Hemiuroidea): tegumental structure and function in the mesocercaria and the metacercaria of Lecithochirium furcolabiatum (Jones, 1933) Dawes, 1947." Journal of Helminthology 62, no. 4 (1988): 317–30. http://dx.doi.org/10.1017/s0022149x0001172x.

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AbstractUltrastructural, histochemical and autoradiographical techniques have been used to investigate the development and function of the tegument of both somal and ecsomal body regions in the hemiurid Lecithochirum furcolabiatum. The terms mesocercaria and metacercaria are here adopted for those stages in the copepod second and fish third intermediate hosts respectively on the basis of morphology and on analogy with the Strigeidae. Mesocercariae were obtained by experimental infection of the harpacticoid copepod Tigriopus brevicornis with the cystophorous cercariae (syn. Cercaria vaullegeard

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14

Peterson, R. Scott, Lakshmi Yarram, Barney A. Schlinger, and Colin J. Saldanha. "Aromatase is pre-synaptic and sexually dimorphic in the adult zebra finch brain." Proceedings of the Royal Society B: Biological Sciences 272, no. 1576 (2005): 2089–96. http://dx.doi.org/10.1098/rspb.2005.3181.

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Oestrogens organize and activate circuits within the vertebrate central nervous system. Oestrogen synthesis occurs via the expression of aromatase, a P 450 enzyme detected in microsomes and more recently in pre-synaptic boutons. Synaptic aromatase has only been described in brain regions that express aromatase in many subcellular compartments, so its function remains poorly understood. To more thoroughly study the role of oestrogen synthesis at synaptic terminals, we examined the ultrastructural compartmentalization of aromatase in the zebra finch; a species in which high aromatase activity ca

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15

Gacek, Richard R., Joanne Schoonmaker, and Michael Lyon. "Morphologic Changes in Contralateral Superior Vestibulo-Ocular Neurons following Labyrinthectomy in the Cat." Annals of Otology, Rhinology & Laryngology 105, no. 10 (1996): 791–94. http://dx.doi.org/10.1177/000348949610501006.

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Ultrastructural changes were measured in 22 contralateral superior vestibulo-ocular neurons (SVONs) from four cats painlessly sacrificed at 8 weeks and 25 contralateral SVONs from four cats sacrificed at 1 year following unilateral labyrinthectomy. The SVONs at 8 weeks showed a 43% decrease in somal size, a 34% loss in rough endoplasmic reticulum (RER), a 48% loss of ribosomes, and a 47% decrease in the number of synaptic profiles (SPs) contacting the soma. At 1 year the SVONs had a 31 % decrease in size, a 43% decrease in RER, a 50% loss of ribosomes, and a 71 % decrease in SPs. Synaptic vesi

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16

Cottrell, Elizabeth C., Rebecca E. Campbell, Seong-Kyu Han, and Allan E. Herbison. "Postnatal Remodeling of Dendritic Structure and Spine Density in Gonadotropin-Releasing Hormone Neurons." Endocrinology 147, no. 8 (2006): 3652–61. http://dx.doi.org/10.1210/en.2006-0296.

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The GnRH neurons represent the output cells of the neuronal network controlling gonadal function. Their activation initiates the onset of puberty, but the underlying mechanisms remain unclear. Using a GnRH-green fluorescent protein mouse model, we have been able to fill individual GnRH neurons with biocytin in the acute brain slice preparation to examine their morphological characteristics across puberty. GnRH neurons in prepubertal male mice [postnatal d 10–15 (PND10–15)] exhibited half as many dendritic and somal spines as adult male mice (&gt;PND60; P &lt; 0.05) but, surprisingly, a

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17

Ostrem, Bridget, Elizabeth Di Lullo, and Arnold Kriegstein. "oRGs and mitotic somal translocation — a role in development and disease." Current Opinion in Neurobiology 42 (February 2017): 61–67. http://dx.doi.org/10.1016/j.conb.2016.11.007.

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18

Rose, R. D., H. R. Koerber, M. J. Sedivec, and L. M. Mendell. "Peripheral nerve Somal action potential duration differs in identified primary afferents." Pain 30, no. 1 (1987): 132. http://dx.doi.org/10.1016/0304-3959(87)90094-7.

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19

Icha, Jaroslav, Christiane Kunath, Mauricio Rocha-Martins, and Caren Norden. "Independent modes of ganglion cell translocation ensure correct lamination of the zebrafish retina." Journal of Cell Biology 215, no. 2 (2016): 259–75. http://dx.doi.org/10.1083/jcb.201604095.

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The arrangement of neurons into distinct layers is critical for neuronal connectivity and function. During development, most neurons move from their birthplace to the appropriate layer, where they polarize. However, kinetics and modes of many neuronal translocation events still await exploration. In this study, we investigate retinal ganglion cell (RGC) translocation across the embryonic zebrafish retina. After completing their translocation, RGCs establish the most basal retinal layer where they form the optic nerve. Using in toto light sheet microscopy, we show that somal translocation of RG

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20

Fogarty, Matthew J., Tanya S. Omar, Wen-Zhi Zhan, Carlos B. Mantilla, and Gary C. Sieck. "Phrenic motor neuron loss in aged rats." Journal of Neurophysiology 119, no. 5 (2018): 1852–62. http://dx.doi.org/10.1152/jn.00868.2017.

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Sarcopenia is the age-related reduction of muscle mass and specific force. In previous studies, we found that sarcopenia of the diaphragm muscle (DIAm) is evident by 24 mo of age in both rats and mice and is associated with selective atrophy of type IIx and IIb muscle fibers and a decrease in maximum specific force. These fiber type-specific effects of sarcopenia resemble those induced by DIAm denervation, leading us to hypothesize that sarcopenia is due to an age-related loss of phrenic motor neurons (PhMNs). To address this hypothesis, we determined the number of PhMNs in young (6 mo old) an

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21

Rana, Sabhya, Carlos B. Mantilla, and Gary C. Sieck. "Glutamatergic input varies with phrenic motor neuron size." Journal of Neurophysiology 122, no. 4 (2019): 1518–29. http://dx.doi.org/10.1152/jn.00430.2019.

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Like all skeletal muscles, the diaphragm muscle accomplishes a range of motor behaviors by recruiting different motor unit types in an orderly fashion. Recruitment of phrenic motor neurons (PhMNs) is generally assumed to be based primarily on the intrinsic properties of PhMNs with an equal distribution of descending excitatory inputs to all PhMNs. However, differences in presynaptic excitatory input across PhMNs of varying sizes could also contribute to the orderly recruitment pattern. In the spinal cord of Sprague-Dawley rats, we retrogradely labeled PhMNs using cholera toxin B (CTB) and vali

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22

Mirnics, Károly, and H. Richard Koerber. "Properties of Individual Embryonic Primary Afferents and Their Spinal Projections in the Rat." Journal of Neurophysiology 78, no. 3 (1997): 1590–600. http://dx.doi.org/10.1152/jn.1997.78.3.1590.

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Mirnics, Károly and H. Richard Koerber. Properties of individual embryonic primary afferents and their spinal projections in the rat. J. Neurophysiol. 78: 1590–1600, 1997. Embryonic (E19-E20) and early postnatal (P2) spinal cords with intact saphenous and sciatic nerves were isolated and placed in aerated artificial cerebral spinal fluid (CSF). Intracellular recordings were made from cells in the L2–L6 dorsal root ganglia using microelectrodes filled with 3 M potassium acetate or 5% neurobiotin (NB) in 1 M potassium acetate. Several physiological properties of adequately impaled cells were mea

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23

Nakamuta, Shinichi, Yu-Ting Yang, Chia-Lin Wang, et al. "Dual role for DOCK7 in tangential migration of interneuron precursors in the postnatal forebrain." Journal of Cell Biology 216, no. 12 (2017): 4313–30. http://dx.doi.org/10.1083/jcb.201704157.

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Throughout life, stem cells in the ventricular–subventricular zone generate neuroblasts that migrate via the rostral migratory stream (RMS) to the olfactory bulb, where they differentiate into local interneurons. Although progress has been made toward identifying extracellular factors that guide the migration of these cells, little is known about the intracellular mechanisms that govern the dynamic reshaping of the neuroblasts’ morphology required for their migration along the RMS. In this study, we identify DOCK7, a member of the DOCK180-family, as a molecule essential for tangential neurobla

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24

Hawthorne, A. L., C. J. Wylie, L. T. Landmesser, E. S. Deneris, and J. Silver. "Serotonergic Neurons Migrate Radially through the Neuroepithelium by Dynamin-Mediated Somal Translocation." Journal of Neuroscience 30, no. 2 (2010): 420–30. http://dx.doi.org/10.1523/jneurosci.2333-09.2010.

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25

Stone, Jonathan, Felix Makarov, and Horstmar Holländer. "The glial ensheathment of the soma and axon hillock of retinal ganglion cells." Visual Neuroscience 12, no. 2 (1995): 273–79. http://dx.doi.org/10.1017/s0952523800007951.

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AbstractWe have studied the glial investment of ganglion cells of the cat's retina, orienting the sections taken for electron microscopy so that the investment could be traced from the soma along the axon. The soma of each ganglion cell is covered by a close-fitting, continuous sheath formed by Müller cells. The axon hillock and the first part of the initial segment are invested by an extension of the somal sheath, and are thus enclosed in the same glial compartment as the soma. The initial segment extends a few microns past the Müller cell sheath; this last length of the initial segment is co

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26

Nadarajah, Bagirathy. "Radial glia and somal translocation of radial neurons in the developing cerebral cortex." Glia 43, no. 1 (2003): 33–36. http://dx.doi.org/10.1002/glia.10245.

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27

Nguyen, Michael P., George D. Bittner, and Harvey M. Fishman. "Critical interval of somal calcium transient after neurite transection determines B104 cell survival." Journal of Neuroscience Research 81, no. 6 (2005): 805–16. http://dx.doi.org/10.1002/jnr.20606.

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28

Sweet, Robert A., Joseph N. Pierri, Sungyoung Auh, Allan R. Sampson, and David A. Lewis. "Reduced Pyramidal Cell Somal Volume in Auditory Association Cortex of Subjects with Schizophrenia." Neuropsychopharmacology 28, no. 3 (2002): 599–609. http://dx.doi.org/10.1038/sj.npp.1300120.

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29

Ritter, A. M., and L. M. Mendell. "The somal spike of physiologically identified high threshold mechanoreceptors is insensitive to TTX." Pain 41 (January 1990): S110. http://dx.doi.org/10.1016/0304-3959(90)92356-u.

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30

Prakash, Y. S., Carlos B. Mantilla, Wen-Zhi Zhan, Kenneth G. Smithson, and Gary C. Sieck. "Phrenic motoneuron morphology during rapid diaphragm muscle growth." Journal of Applied Physiology 89, no. 2 (2000): 563–72. http://dx.doi.org/10.1152/jappl.2000.89.2.563.

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In the adult rat, there is a general correspondence between the sizes of motoneurons, motor units, and muscle fibers that has particular functional importance in motor control. During early postnatal development, after the establishment of singular innervation, there is rapid growth of diaphragm muscle (Diam) fibers. In the present study, the association between Diamfiber growth and changes in phrenic motoneuron size (both somal and dendritic) was evaluated from postnatal day 21 (D21) to adulthood. Phrenic motoneurons were retrogradely labeled with fluorescent tetramethylrhodamine dextran (3,0

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31

Pottie, Lore, Wouter Van Gool, Michiel Vanhooydonck, et al. "Loss of zebrafish atp6v1e1b, encoding a subunit of vacuolar ATPase, recapitulates human ARCL type 2C syndrome and identifies multiple pathobiological signatures." PLOS Genetics 17, no. 6 (2021): e1009603. http://dx.doi.org/10.1371/journal.pgen.1009603.

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The inability to maintain a strictly regulated endo(lyso)somal acidic pH through the proton-pumping action of the vacuolar-ATPases (v-ATPases) has been associated with various human diseases including heritable connective tissue disorders. Autosomal recessive (AR) cutis laxa (CL) type 2C syndrome is associated with genetic defects in the ATP6V1E1 gene and is characterized by skin wrinkles or loose redundant skin folds with pleiotropic systemic manifestations. The underlying pathological mechanisms leading to the clinical presentations remain largely unknown. Here, we show that loss of atp6v1e1

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32

Kaneko, Hiroshi, Tadashi Nakamura, and Bernd Lindemann. "Noninvasive measurement of chloride concentration in rat olfactory receptor cells with use of a fluorescent dye." American Journal of Physiology-Cell Physiology 280, no. 6 (2001): C1387—C1393. http://dx.doi.org/10.1152/ajpcell.2001.280.6.c1387.

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Inwardly directed Ca2+-dependent chloride currents are thought to prolong and boost the odorant-induced transient receptor currents in olfactory cilia. Cl− inward current, of course, requires a sufficiently high intracellular Cl− concentration ([Cl−]i). In previous measurements using a fluorescent Cl− probe, N-(ethoxycarbonylmethyl)-6-methoxyquinolinium bromide (MQAE), [Cl−]i of newt olfactory cells was estimated to be only 40 mM. This low value led us to reexamine the [Cl−]i by an improved procedure. When isolated rat olfactory neurons were bathed in Tyrode's solution (150 mM Cl−) at room tem

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33

Gonçalves, João Carlos, Tiago J. Dantas, and Richard B. Vallee. "Distinct roles for dynein light intermediate chains in neurogenesis, migration, and terminal somal translocation." Journal of Cell Biology 218, no. 3 (2019): 808–19. http://dx.doi.org/10.1083/jcb.201806112.

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Cytoplasmic dynein participates in multiple aspects of neocortical development. These include neural progenitor proliferation, morphogenesis, and neuronal migration. The cytoplasmic dynein light intermediate chains (LICs) 1 and 2 are cargo-binding subunits, though their relative roles are not well understood. Here, we used in utero electroporation of shRNAs or LIC functional domains to determine the relative contributions of the two LICs in the developing rat brain. We find that LIC1, through BicD2, is required for apical nuclear migration in neural progenitors. In newborn neurons, we observe

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34

Maldonado-Avilés, Jaime G., Qiang Wu, Allan R. Sampson, and David A. Lewis. "Somal Size of Immunolabeled Pyramidal Cells in the Prefrontal Cortex of Subjects with Schizophrenia." Biological Psychiatry 60, no. 3 (2006): 226–34. http://dx.doi.org/10.1016/j.biopsych.2005.10.028.

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Mitrofanis, John. "NADPH-diaphorase reactivity in the ventral and dorsal lateral geniculate nuclei of rats." Visual Neuroscience 9, no. 2 (1992): 211–16. http://dx.doi.org/10.1017/s0952523800009676.

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AbstractThe present study describes the patterns of NADPH-diaphorase reactivity in the ventral and dorsal lateral geniculate nuclei of rats. In the ventral lateral geniculate nucleus, two distinct populations of NADPH-diaphorase reactive cells are apparent. One population is deeply stained, generally larger in somal size and located in the more superficial or dorsolateral regions of the nucleus. The second population of reactive cells in the nucleus is lightly labeled, small in somal size, and found in deeper or more ventromedial regions of the nucleus. Double labeling with an antibody to GAB

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Geddes, James W., Claudia Schwab, Susan Craddock, Janice L. Wilson та L. Creed Pettigrew. "Alterations in τ Immunostaining in the Rat Hippocampus following Transient Cerebral Ischemia". Journal of Cerebral Blood Flow & Metabolism 14, № 4 (1994): 554–64. http://dx.doi.org/10.1038/jcbfm.1994.69.

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Previous studies in gerbils have shown that cytoskeletal disruption and a loss of the dendritic microtubule-associated protein, MAP2, may occur after short periods of transient global ischemia. τ, a predominantly axonal microtubule-associated protein, has not been examined following ischemia. We compared neuronal damage with alterations in MAP2, τ, and 72-kD heat shock protein (HSP72) immunostaining at various reperfusion times following 20 min of ischemia in the rat four-vessel occlusion model. τ accumulated in neuronal cell bodies throughout the hippocampal formation 30 min to 2 h after the

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Al-Tamimi, Yahia Z., Atul K. Tyagi, Paul D. Chumas, and Darach W. Crimmins. "Patients with autosomal-recessive osteopetrosis presenting with hydrocephalus and hindbrain posterior fossa crowding." Journal of Neurosurgery: Pediatrics 1, no. 1 (2008): 103–6. http://dx.doi.org/10.3171/ped-08/01/103.

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✓ Osteopetrosis is a heterogeneous group of disorders characterized by abnormal bone sclerosis. As a result, patients often require input regarding various neurological complications. Although autosomal-recessive osteopetrosis has been associated with hydrocephalus, it has not been linked to hindbrain abnormalities. The authors present 3 cases of auto-somal-recessive osteopetrosis in patients who presented with hydrocephalus. In each of these patients, cerebrospinal fluid diversion procedures were required and hindbrain compression developed. To date, only 1 patient has needed craniocervical d

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38

Boada, M. Danilo, and C. Jeffery Woodbury. "Physiological Properties of Mouse Skin Sensory Neurons Recorded Intracellularly In Vivo: Temperature Effects on Somal Membrane Properties." Journal of Neurophysiology 98, no. 2 (2007): 668–80. http://dx.doi.org/10.1152/jn.00264.2007.

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Recent combined analyses of the structural, functional, and molecular attributes of individual skin sensory neurons using semi-intact in vitro preparations from mice have provided a wealth of novel insights into nociceptor biology. How these findings translate to more natural conditions nevertheless remains unresolved. Toward this end, intracellular recordings were obtained from 362 physiologically identified dorsal root ganglion (DRG) neurons in a new in vivo mouse preparation developed for combined structure/function analyses of individual skin sensory neurons. Recordings were conducted at t

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39

Poché, Ross A., Mary A. Raven, Kin Ming Kwan, Yasuhide Furuta, Richard R. Behringer, and Benjamin E. Reese. "Somal positioning and dendritic growth of horizontal cells are regulated by interactions with homotypic neighbors." European Journal of Neuroscience 27, no. 7 (2008): 1607–14. http://dx.doi.org/10.1111/j.1460-9568.2008.06132.x.

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40

Leong, Seng-Kee, and Wai-Chow Wong. "Comparing the Somal Size and Nuclear Positions of the Monkey Stellate and Coeliac Ganglion Cells." Cells Tissues Organs 138, no. 4 (1990): 281–84. http://dx.doi.org/10.1159/000146956.

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41

Virga, Daniel M., Jessica Capps, and Bhupinder P. S. Vohra. "Enteric Neurodegeneration is Mediated Through Independent Neuritic and Somal Mechanisms in Rotenone and MPP+ Toxicity." Neurochemical Research 43, no. 12 (2018): 2288–303. http://dx.doi.org/10.1007/s11064-018-2649-x.

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42

Prakash, Y. S., K. G. Smithson, and G. C. Sieck. "Measurements of Motoneuron Somal Volumes Using Laser Confocal Microscopy: Comparisons with Shape-Based Stereological Estimations." NeuroImage 1, no. 2 (1993): 95–107. http://dx.doi.org/10.1006/nimg.1993.1003.

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43

Kahle, Philipp J., Manuela Neumann, Laurence Ozmen та ін. "Somal and neuritic accumulation of the Parkinson's disease-associated mutant [A30P]α-synuclein in transgenic mice". Neurobiology of Aging 21 (травень 2000): 132. http://dx.doi.org/10.1016/s0197-4580(00)82394-5.

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44

Yoo, Soonmoon, Jane E. Bottenstein, George D. Bittner, and Harvey M. Fishman. "Survival of mammalian B104 cells following neurite transection at different locations depends on somal Ca2+ concentration." Journal of Neurobiology 60, no. 2 (2004): 137–53. http://dx.doi.org/10.1002/neu.20005.

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45

Pilato, Celeste M., Jae Hong Park, Lingling Kong, et al. "Motor neuron loss in SMA is not associated with somal stress-activated JNK/c-Jun signaling." Human Molecular Genetics 28, no. 19 (2019): 3282–92. http://dx.doi.org/10.1093/hmg/ddz150.

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Abstract A pathological hallmark of spinal muscular atrophy (SMA) is severe motor neuron (MN) loss, which results in muscle weakness and often infantile or childhood mortality. Although it is well established that deficient expression of survival motor neuron (SMN) protein causes SMA, the molecular pathways that execute MN cell death are poorly defined. The c-Jun NH2-terminal kinases (JNKs) are stress-activated kinases with multiple substrates including c-Jun, which can be activated during neuronal injury and neurodegenerative disease leading to neuronal apoptosis. Recently, increased JNK-c-Ju

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Collins, William F., Andrew W. Seymour, and Sharon W. Klugewicz. "Differential effect of castration on the somal size of pudendal motoneurons in the adult male rat." Brain Research 577, no. 2 (1992): 326–30. http://dx.doi.org/10.1016/0006-8993(92)90292-h.

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Fernandes, Kimberly A., Katherine L. Mitchell, Amit Patel, et al. "Role of SARM1 and DR6 in retinal ganglion cell axonal and somal degeneration following axonal injury." Experimental Eye Research 171 (June 2018): 54–61. http://dx.doi.org/10.1016/j.exer.2018.03.007.

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Elliott, Alan S., and Antonio A. Nunez. "An ultrastructural study of somal appositions in the suprachiasmatic nucleus and anterior hypothalamus of the rat." Brain Research 662, no. 1-2 (1994): 278–82. http://dx.doi.org/10.1016/0006-8993(94)90826-5.

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Matar, Elie, Daniel Brooks, Antony Harding, and Glenda Halliday. "110 Atrophy of the mediodorsal thalamus is associated with visual hallucinations in lewy body diseases." Journal of Neurology, Neurosurgery & Psychiatry 89, no. 6 (2018): A43.3—A44. http://dx.doi.org/10.1136/jnnp-2018-anzan.109.

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Abstract:

IntroductionAlthough limbic system dysfunction has been thought to underlie visual hallucinations in patients with Lewy body disorders, neuropathology within thalamic structures subserving limbic functions have not been examined. In this study, we assessed the degree of neuronal degeneration in thalamic regions involved in perceptual integration in patients with Parkinson’s disease (PD), Parkinson’s disease dementia (PDD) and dementia with Lewy bodies (DLB).MethodsPost-mortem samples were acquired from twenty-four individuals with Lewy body disease (5 PD, 9 PDD, 10 DLB) and 10 age-matched cont

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EGLEN, STEPHEN J., PETER J. DIGGLE, and JOHN B. TROY. "Homotypic constraints dominate positioning of on- and off-center beta retinal ganglion cells." Visual Neuroscience 22, no. 6 (2005): 859–71. http://dx.doi.org/10.1017/s0952523805226147.

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Abstract:

Beta retinal ganglion cells (RGCs) of the cat are classified as either on-center or off-center, according to their response to light. The cell bodies of these on- and off-center RGCs are spatially distributed into regular patterns, known as retinal mosaics. In this paper, we investigate the nature of spatial dependencies between the positioning of on- and off-center RGCs by analysing maps of RGCs and simulating these patterns. We introduce principled approaches to parameter estimation, along with likelihood-based techniques to evaluate different hypotheses. Spatial constraints between cells wi

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