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Journal articles on the topic 'Somatic beauty'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

BOYKO, Nadiia. "«Eyes burn words, words burn eyelids» (Imaginary potential of somatisms in the poetic picture of the world of Mykola Vinhranovskyi)." Culture of the Word, no. 96 (2022): 165–75. http://dx.doi.org/10.37919/0201-419x-2022.96.12.

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The article clarifies the peculiarities of the use of somatic units belonging to the general language dictionary; their imaginative potential is revealed in Mykola VinHranovskyi's poetic picture of the world. A wide range of figurative use of somatic lexemes is noted, the semantic specificity of their functioning is substantiated – due to the combination with ethnically marked words-images dream, hope, song, beauty, love, etc.; the introduction of original, unusually modeled tropeic, emotional and evaluative structures. Processes of image formation based on associative convergences of direct a

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2

Saumaa, Hiie. "“I Feel Beautiful When I Dance”: Beauty and Somatic Dance." Integrative and Complementary Therapies 29, no. 3 (2023): 125–29. http://dx.doi.org/10.1089/ict.2023.29072.hsa.

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3

Chung, Jae-Dong, Hong-Yul Kim, Jung-Hae Suh, Oh-Chang Kwon, and Chang-kil Kim. "(80) Direct Somatic Embryogenesis from Thin-section Leaf Explant of Phalaenopsis Hybrids." HortScience 41, no. 4 (2006): 1066D—1067. http://dx.doi.org/10.21273/hortsci.41.4.1066d.

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Somatic embryo formation was observed on thin-sectioned leaf explants within 3 weeks of culture from two Phalaenopsis hybrids—Phalaenopsis Hwafeng Redjewell `Ching Ruey' Phalaenopsis Chingruey's Giant Ching Ruey' (R×R), and Phalaenopsis Formosa Best Girl Ching Ruey' Depts. Lih Jiang Beauty `S 566' (WR×WR). Frequency of somatic embryo formation was higher in hybrid WRxWR than R×R and optimal concentration of TDZ for the induction of somatic embryos was 9.08 μM. In (WR×WR) embryo proliferation was simultaneously observed after transferring the explants with somatic embryo clumps onto PGR-free ha

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Dupuy, Adam J., Keiko Akagi, David A. Largaespada, Neal G. Copeland, and Nancy A. Jenkins. "Mammalian mutagenesis using a highly mobile somatic Sleeping Beauty transposon system." Nature 436, no. 7048 (2005): 221–26. http://dx.doi.org/10.1038/nature03691.

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5

Turchiano, Giandomenico, Maria Carmela Latella, Andreas Gogol-Döring, et al. "Genomic Analysis of Sleeping Beauty Transposon Integration in Human Somatic Cells." PLoS ONE 9, no. 11 (2014): e112712. http://dx.doi.org/10.1371/journal.pone.0112712.

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6

Nannini, Alessandro. "Baumgarten’s Diet: Physical Exercise, Health, and Beauty." Aisthesis. Pratiche, linguaggi e saperi dell’estetico 15, no. 2 (2023): 137–46. http://dx.doi.org/10.36253/aisthesis-13721.

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In this paper, I intend to analyze Baumgarten’s position about the dietetic care of the body in its relation to nascent aesthetics, with special regard to the problem of physical exercise. On the one hand, I will show that physical exercise can acquire aesthetic value with the example of the somatic fine arts. On the other hand, I will demonstrate that dietetics is also seminal for the emergence of every act of beautiful thinking. Eventually, I will bring to the fore the dietetic potential of beauty itself. In this way, it will be possible to better appraise the constitutive link between healt

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7

Korngold, Ana, Lin-Kin Yong, Ugochi Ibekwe, et al. "226 Neoantigen-specific TCR-T cells targeting shared hotspot mutations for adoptive cell therapy in common epithelial cancers." Journal for ImmunoTherapy of Cancer 9, Suppl 2 (2021): A240. http://dx.doi.org/10.1136/jitc-2021-sitc2021.226.

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BackgroundEGFR, KRAS and TP53 have frequent somatic hotspot mutations giving rise to biologically relevant amino acid substitutions in EGFR, KRAS and p53 proteins, respectively, that can be processed and presented on the cell surface by human leukocyte antigen (HLA) molecules as neoantigens to T cells through their T-cell receptor (TCR). These mutations are critical for the cancer cell and are absent in normal tissue; thus, these shared neoantigens are attractive and likely safe targets. Given the complexity of different neoantigen/HLA combinations needed to effectively target a large patient

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Царенок, Андрій Вікторович. "ЕСТЕТИЧНИЙ ПОТЕНЦІАЛ ВІЗАНТІЙСЬКОЇ АСКЕТИКИ". Філософські обрії, № 37 (14 червня 2017): 111–23. https://doi.org/10.5281/zenodo.808788.

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As the author of the article proves, the thorough exploration of the Byzantine ascetic doctrine makes possible understanding of its great philosophical and aesthetical potential and value. Trying to point out the aesthetical senses of the Byzantine ascetic theology, the scientists must take into consideration, first of all, the outstanding role of Christian theocentrism and monotheism (Trinitary monotheism) as the factors of the develop-ment of the corresponding aesthetical tradition. As a matter of fact, Christian aesthetics (philosophy of beauty) can be re-garded as the true theocentrical on

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9

Kim, SeungJung. "Kairos, The Sire of Beauty." Philosophy & Rhetoric 56, no. 3-4 (2023): 274–86. http://dx.doi.org/10.5325/philrhet.56.3-4.0274.

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ABSTRACT Despite the common understanding of kairos as a temporal concept, it also harbors a spatial notion that holds particular significance in relation to Greek visual arts. The inquiry into its primary role in the formation of aesthetic beauty requires a phenomenological reading of the Lysippan personification of the concept, as it resonates with its counterparts in the fields of philosophy, rhetoric, and medicine. Using Andrew Stewart’s suggestion as a starting point—that the Lysippan Kairos may serve as the artist’s manifesto, consciously constructed in response to the earlier Polykleita

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10

Turchiano, Giandomenico, Maria Carmela Latella, Andreas Gogol Döring, et al. "Correction: Genomic Analysis of Sleeping Beauty Transposon Integration in Human Somatic Cells." PLOS ONE 15, no. 1 (2020): e0228703. http://dx.doi.org/10.1371/journal.pone.0228703.

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11

Moriarity, Branden, and David A. Largaespada. "A Comprehensive Guide to Sleeping Beauty–Based Somatic Transposon Mutagenesis in the Mouse." Current Protocols in Mouse Biology 1, no. 3 (2011): 347–68. http://dx.doi.org/10.1002/9780470942390.mo110087.

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12

Bender, Aaron M., Lara S. Collier, Fausto J. Rodriguez, et al. "Sleeping Beauty–Mediated Somatic Mutagenesis Implicates CSF1 in the Formation of High-Grade Astrocytomas." Cancer Research 70, no. 9 (2010): 3557–65. http://dx.doi.org/10.1158/0008-5472.can-09-4674.

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13

Jacob, Julia. "Beauty and Civilisation. Buffon's considerations on human somatic features in Histoire Naturelle de l'Homme." Aesthetic Investigations 4, no. 2 (2021): 219–35. https://doi.org/10.5281/zenodo.5482963.

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The presence of an aesthetic judgment in an anthropological, scientific study may seem incongruous. One would think that the human body should be approached only in terms of ‘objective’ criteria of functionality and measurable proportions. However, to our surprise, two adjectives keep coming up in Buffon’s description of the human body in his <em>Histoire naturelle de l’Homme</em>: ‘beautiful’ and ‘ugly’. To be sure, it is possible to determine that a person is beautiful through measurements and observations of bodily and facial symmetry, but mos

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14

Devaraj, Anantharam, Manvendra Singh, Suneel A. Narayanavari, et al. "HMGXB4 Targets Sleeping Beauty Transposition to Germinal Stem Cells." International Journal of Molecular Sciences 24, no. 8 (2023): 7283. http://dx.doi.org/10.3390/ijms24087283.

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Transposons are parasitic genetic elements that frequently hijack vital cellular processes of their host. HMGXB4 is a known Wnt signaling-regulating HMG-box protein, previously identified as a host-encoded factor of Sleeping Beauty (SB) transposition. Here, we show that HMGXB4 is predominantly maternally expressed, and marks both germinal progenitor and somatic stem cells. SB piggybacks HMGXB4 to activate transposase expression and target transposition to germinal stem cells, thereby potentiating heritable transposon insertions. The HMGXB4 promoter is located within an active chromatin domain,

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15

Jumanazarov, Samandar Urinovich. "The Reflection of Human External Appearance through Somatic Phraseological Units in English and Uzbek Languages." Multidisciplinary Journal of Science and Technology 5, no. 5 (2025): 1152–54. https://doi.org/10.5281/zenodo.15511813.

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<em>This paper explores how somatic phraseological units (SPUs), which are idioms involving human body parts, reflect the external, physical characteristics of individuals in both English and Uzbek languages. By analyzing idioms and expressions that depict physical appearance, this study identifies how cultures encode physical traits, beauty, and bodily impressions through language. The findings reveal both universal trends and culturally specific perspectives that shape how external human image is conceptualized. The article presents theoretical ideas in this regard and proves them with examp

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16

Semashko, Tatiana. "Somatic cultural code of Ukrainians through the prism ofperceptive stereotyping." Przegląd Wschodnioeuropejski 8, no. 1 (2017): 281–88. http://dx.doi.org/10.31648/pw.3619.

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Anthropocentric principle and cognitive and discursive paradigm, which today are leading in the linguistics, condition the study of complex cognitive processes, in which ethnocultural perceptive stereotypes play special role as important components of linguocultural space, which are able to act as the translator of somatic cultural code of Ukrainians and to reveal the depths of sacral essence of archaic thinking of the ethnos through the system of natural ethnically deep-rooted codes. Against the background of significant variety of anthropological types of Ukrainian population modern Ukrainia

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17

McGrail, Maura, Julia M. Hatler, Xianyan Kuang, et al. "Somatic Mutagenesis with a Sleeping Beauty Transposon System Leads to Solid Tumor Formation in Zebrafish." PLoS ONE 6, no. 4 (2011): e18826. http://dx.doi.org/10.1371/journal.pone.0018826.

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18

Garrels, W., T. R. Talluri, R. Bevacqua, et al. "356 SLEEPING BEAUTY TRANSGENESIS IN CATTLE." Reproduction, Fertility and Development 27, no. 1 (2015): 266. http://dx.doi.org/10.1071/rdv27n1ab356.

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Transposon-mediated transgenesis is a well-established tool for genome modification in small animal models. However, translation of this active transgenic method to large animals warrants further investigations. Here, the Sleeping Beauty (SB) transposon system was assessed for stable gene transfer into the cattle genome. The transposon plasmids encoded a ubiquitously active CAGGS promoter-driven Venus reporter and a lens-specific α A-crystallin promoter driven tdTomato fluorophore, respectively. The helper plasmid carried the hyperactive SB100x transposase variant. In total, 50 in vitro-derive

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19

Rauschhuber, Christina, and Anja Ehrhardt. "RNA Interference Is Responsible for Reduction of Transgene Expression after Sleeping Beauty Transposase Mediated Somatic Integration." PLoS ONE 7, no. 5 (2012): e35389. http://dx.doi.org/10.1371/journal.pone.0035389.

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20

Carlson, C. M., J. L. Frandsen, N. Kirchhof, R. S. McIvor, and D. A. Largaespada. "Somatic integration of an oncogene-harboring Sleeping Beauty transposon models liver tumor development in the mouse." Proceedings of the National Academy of Sciences 102, no. 47 (2005): 17059–64. http://dx.doi.org/10.1073/pnas.0502974102.

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21

Hammer, Kimberly D. P., James D. Alsop, Rita A. Buresh-Stiemke, et al. "A novel method for somatic transgenesis of the mouse prostate using the Sleeping Beauty transposon system." Prostate 74, no. 7 (2014): 781–91. http://dx.doi.org/10.1002/pros.22797.

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22

Izsvák, Zsuzsanna, Eva E. Stüwe, Dora Fiedler, Andrea Katzer, Penny A. Jeggo, and Zoltán Ivics. "Healing the Wounds Inflicted by Sleeping Beauty Transposition by Double-Strand Break Repair in Mammalian Somatic Cells." Molecular Cell 13, no. 2 (2004): 279–90. http://dx.doi.org/10.1016/s1097-2765(03)00524-0.

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23

Zhang, Wenli, Martin Muck-Hausl, Jichang Wang, et al. "Integration Profile and Safety of an Adenovirus Hybrid-Vector Utilizing Hyperactive Sleeping Beauty Transposase for Somatic Integration." PLoS ONE 8, no. 10 (2013): e75344. http://dx.doi.org/10.1371/journal.pone.0075344.

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24

Kubrak, Olga I., Lucie Kučerová, Ulrich Theopold, and Dick R. Nässel. "The Sleeping Beauty: How Reproductive Diapause Affects Hormone Signaling, Metabolism, Immune Response and Somatic Maintenance in Drosophila melanogaster." PLoS ONE 9, no. 11 (2014): e113051. http://dx.doi.org/10.1371/journal.pone.0113051.

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25

Zhang, Wenli, Martin Muck-Hausl, Jichang Wang, et al. "Correction: Integration Profile and Safety of an Adenovirus Hybrid-Vector Utilizing Hyperactive Sleeping Beauty Transposase for Somatic Integration." PLOS ONE 15, no. 2 (2020): e0228902. http://dx.doi.org/10.1371/journal.pone.0228902.

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26

Talluri, T. R., D. Hermann, B. Barg-Kues, et al. "305 TRANSPOSON-MEDIATED REPROGRAMMING OF LIVESTOCK SOMATIC CELLS TO INDUCED PLURIPOTENT STEM CELLS." Reproduction, Fertility and Development 25, no. 1 (2013): 300. http://dx.doi.org/10.1071/rdv25n1ab305.

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The elusive nature of embryonic stem cells in livestock makes reprogramming of somatic cells to induced pluripotent stem (iPS) cells a promising approach for targeted genetic modifications. The first attempts to produce iPS cells from livestock species were made using retro- and lentiviral vectors, which are associated with an increased risk of insertional mutagenesis and which are not easily removable after reprogramming. Here, we describe a nonviral method for the derivation of porcine and bovine iPS cells, using Sleeping Beauty (SB) and piggyBac (PB) transposon systems. The transposons enco

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27

Elders, Red K. "See yourself through these hands: The moving body as a portal to spirit possession. Working with ancient ritual technologies to create portraits of spirits, gods and mythic beings." Dance, Movement & Spiritualities 9, no. 1 (2022): 99–118. http://dx.doi.org/10.1386/dmas_00037_1.

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My creative, somatic and spiritual praxis combines the deep somatic trance work of authentic movement with ancient ritual technologies such as those found in the 2000-year-old Greek Magical Papyri. This article describes these embodied processes in and with wild nature places to facilitate visionary states which are recorded through poetic writings, and subsequently expressed in highly detailed drawings of ancient gods and mythic beings. I explore the nature of creative inspiration, not only in my own writings and drawings but in others’ artistic endeavours, that leads me to consider whether w

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28

Petkov, S., M. Nowak-Imialek, P. Hyttel, and H. Niemann. "307 REPROGRAMMING OF PIG SOMATIC CELLS TO PLURIPOTENCY WITH SLEEPING BEAUTY TRANSPOSON VECTORS CONTAINING THE PORCINE TRANSCRIPTION FACTOR SEQUENCES." Reproduction, Fertility and Development 25, no. 1 (2013): 300. http://dx.doi.org/10.1071/rdv25n1ab307.

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Induced pluripotent stem cells (iPSC), developed by Yamanaka and co-workers (Takahashi et al., 2006), hold significant potential for the development of regenerative therapies due to the possibilities of deriving patient-specific pluripotent cells. In this aspect, the pig is an important animal model for testing iPSC-based applications for the human medicine. However, even though significant progress has been made, the derivation of porcine iPSC lines fully equivalent to those from mouse and human has been elusive. To date, most of the reported putative pig iPSC lines have been derived with the

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Wilber, Andrew, Joel L. Frandsen,, Jennifer L. Geurts, David A. Largaespada, Perry B. Hackett, and R. Scott McIvor. "RNA as a Source of Transposase for Sleeping Beauty-Mediated Gene Insertion and Expression in Somatic Cells and Tissues." Molecular Therapy 13, no. 3 (2006): 625–30. http://dx.doi.org/10.1016/j.ymthe.2005.10.014.

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30

Kaur, Harpreet, and Amandeep Rana. "From Pure Aesthetics to Sensory Gratification: Shifting Paradigm of Aesthetic Pleasure in Indian Popular Campus Fiction." International Journal of English and Comparative Literary Studies 3, no. 3 (2022): 13–28. http://dx.doi.org/10.47631/ijecls.v3i3.436.

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This paper explores the shifting paradigm of ‘aesthetic pleasure’ in the field of popular literature with an emergence of cultural studies in Literary Theory. It focuses on the concept of pleasure as a significant measure in analyzing the origin and development of Indian popular campus fiction as a distinct genre. It examines how the concept of ‘pleasure’ has shifted from a purely aesthetic appreciation of the values of truth, beauty and goodness to the contemporary aspects of hedonistic and somatic pleasures in the works of popular arts. The paper also sheds light on various theories, propoun

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31

Rahrmann, Eric P., Lara S. Collier, Todd P. Knutson, et al. "Identification of PDE4D as a Proliferation Promoting Factor in Prostate Cancer Using a Sleeping Beauty Transposon-Based Somatic Mutagenesis Screen." Cancer Research 69, no. 10 (2009): 4388–97. http://dx.doi.org/10.1158/0008-5472.can-08-3901.

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32

Schoonheim, Liesbeth. "The Productive Body." Philosophy Today 63, no. 2 (2019): 471–89. http://dx.doi.org/10.5840/philtoday2019813277.

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This essay aims to correct the widely-held view that Arendt is hostile to the body due to its physical needs. By focusing on two modes of corporeality that are distinguished by the production of bodily substances—the digestive body and the crying body—I argue that Arendt (1) deployed various notions of corporeality that thematize, in different ways, the uncontrollability our bodies; and (2) argues for the affirmation of this unmasterablity because it corresponds to the conditioned nature of human existence. Firstly, Arendt criticized the Greek, narcissistic aspiration toward physical beauty, e

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33

Restanto, Didik Pudji, Iqbal Felayati, Wahyu Indra Duwi Fanata, et al. "Optimization of TDZ Hormone on the Formation of Somatic Embryogenesis in Dendrobium Orchids (D.50TH Stage Beauty X D. Bobby Mesina)." Jurnal Natur Indonesia 21, no. 1 (2023): 42. http://dx.doi.org/10.31258/jnat.21.1.42-46.

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The Dendrobium variety orchid is a plant that has rare potential and growth. This requires large amounts of seeds that can be propagated in vitro. This study aims to determine the effect of TDZ on the direct induction of somatic embryogenesis. The study was conducted using a completely randomized design (CRD) with one factor, namely media consisting of basal Murashige and Skoog (MS) media with growth regulator TDZ. Each treatment out of a total of seven treatments was repeated four times. The research was carried out from March 2022 to August 2022. The results showed that leaf explants (clonal

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34

Семашко, Тетяна Федорівна. "ПЕРЦЕПТИВНИЙ ОБРАЗ ФІЗИЧНОЇ КРАСИ УКРАЇНЦІВ В АСПЕКТІ ЕТНІЧНОЇ СТЕРЕОТИПІЗАЦІЇ". Збірник наукових праць ХНПУ імені Г.С. Сковороди "Лінгвістичні дослідження", № 43 (6 квітня 2016): 130–36. https://doi.org/10.5281/zenodo.49215.

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Anthropocentric principle and cognitive and discursive paradigm, which today are leading in the linguistics, condition the study of complex cognitive processes, in which ethno-cultural perceptive stereotypes play special role as important components of linguocultural space, which are able to act as the translator of somatic cultural code of Ukrainians and to reveal the depths of sacral essence of archaic thinking of the ethnos through the system of natural ethnically deep-rooted codes. Against the background of significant variety of anthropological types of Ukrainian population modern Ukraini

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35

Wani, N. A., V. S. Binoy, and S. B. Hong. "34 Recent Advances in Cloning by Somatic Cell Nuclear Transfer in Camelids." Reproduction, Fertility and Development 30, no. 1 (2018): 156. http://dx.doi.org/10.1071/rdv30n1ab34.

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In addition to its application for production of elite males, racing champions, animals with the highest potential for milk production, and the prized beauty camels, somatic cell nuclear transfer (SCNT) can be utilised for the conservation of endangered wild Bactrian camels and vicunas by using the technique of interspecies SCNT (iSCNT). In the present study, embryos were reconstructed by using skin fibroblast cells from a Bactrian camel (Camelus bactrianus), a llama (Llama glama), and a dromedary camel (Camelus dromedarius) as donor karyoplasts and dromedary oocytes as recipient cytoplasts to

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36

Fili, A. E., A. P. Alessio, W. Garrels, et al. "242 HIGHLY EFFICIENT SLEEPING BEAUTY TRANSPOSON-MEDIATED TRANSGENESIS IN BOVINE FETAL FIBROBLASTS." Reproduction, Fertility and Development 28, no. 2 (2016): 253. http://dx.doi.org/10.1071/rdv28n2ab242.

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Active transposon-mediated transgenesis is an emerging tool for basic and applied research in livestock. We have demonstrated the effectiveness of a helper-independent piggyBac transposon (pGENIE-3) for gene transfer into the genome of bovine cells (Alessio et al. 2014 Reprod. Domest. Anim. 49, 8). Here, we extend our previous research by examining the suitability of a Sleeping Beauty (SB) transposon-based methodology to deliver transgenes into the genome of bovine fetal fibroblasts (BFF), and the ability of these cells to support in vitro embryo development upon somatic cell nuclear transfer

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37

Carlson, D. F., J. R. Dobrinsky, and S. C. Fahrenkrug. "327 HIGH EFFICIENCY SWINE CLONING USING MONOGENIC AND POLYGENIC POOLS OF GENETICALLY MODIFIED CELLS." Reproduction, Fertility and Development 23, no. 1 (2011): 260. http://dx.doi.org/10.1071/rdv23n1ab327.

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Somatic cell nuclear transfer (SCNT) of genetically modified (GM) cells is currently the most widely applied method for the creation of transgenic swine. However, significant clone-to-clone variation in the efficiency of SCNT for a variety of genetically modified cell lines is commonly observed and contributes to the expense of transgenic animal production. A retrospective look at our own results based on the use of monoclonal GM cell lines as donors revealed a dismal efficiency of only 13% (15 embryo transfers resulting in only 2 full term pregnancies). Thus, while SCNT of individual GM clone

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38

Palmer, Clive, and David Torevell. "‘The Sweet Pain of Life’ - Dancing Metaphysical Longing: A Theological Reading of Matthew Bourne’s Swan Lake." International Journal of Social Science Studies 8, no. 2 (2020): 63. http://dx.doi.org/10.11114/ijsss.v8i2.4722.

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The performing arts offer opportunities for the creative representation of spiritual and moral values and serve an important function in contemporary culture. Dance, and in particular ballet, has the potential through its somatic dynamics centred around graceful movement and stylised gesture, to offer an alluring spectacle of beauty and value to any audience. What we offer in this article is a philosophical, theological and spiritual reading of Matthew Bourne’s 2018 production of Swan Lake. The dance revolves around the longing of one male swan for another and the obstacles they encounter due

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39

Petkov, Stoyan, Zoltan Ivics, and Heiner Niemann. "PROGRESS TOWARDS THE DERIVATION OF PORCINE INDUCED PLURIPOTENT STEM CELLS." Reproduction, Fertility and Development 24, no. 1 (2012): 284. http://dx.doi.org/10.1071/rdv24n1ab243.

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Porcine induced pluripotent cells (iPSC) are considered an important large animal model for developing personalized stem cell therapies. Since the derivation of the first mouse and human iPSC, there have been relatively few reports regarding the reprogramming of pig somatic cells into pluripotency, exclusively with the use of transcription factors from human and mouse origin. To investigate whether using species-specific transcription factors would allow for an efficient reprogramming of porcine somatic cells, we have developed a Sleeping Beauty (SB) transposon system based on the porcine OCT4

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40

Dorozhenok, Igor Yu, Elena S. Snarskaya, and Mariana Mikhailova. "Lichen planus and itch-related psychosomatic disorders." Russian Journal of Skin and Venereal Diseases 24, no. 6 (2022): 543–51. http://dx.doi.org/10.17816/dv100612.

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BACKGROUND: The relevance of studying psychosomatic disorders associated with itching in patients with lichen planus (LP) is due to a wide range of transnosological comorbidity of nosogenic and depressive disorders with clinical phenotypes of LP. AIMS: Clinical verification and typological differentiation of psychosomatic disorders associated with itching in accordance with the LP phenotypes we identified in patients of the studied sample. MATERIALS AND METHODS: 120 patients (77 women and 43 men, average age 47.65.2 years) with various LP phenotypes and comorbid psychosomatic disor

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Ehrhardt, Anja, Hui Xu, Zan Huang, Jeffrey A. Engler та Mark A. Kay. "A direct comparison of two nonviral gene therapy vectors for somatic integration: in vivo evaluation of the bacteriophage integrase ϕC31 and the Sleeping Beauty transposase". Molecular Therapy 11, № 5 (2005): 695–706. http://dx.doi.org/10.1016/j.ymthe.2005.01.010.

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42

Białas, Mateusz. "Vers l'esthétique du corps « libéré » : étude du lexique somatique dans le discours pornographique externe." Linguodidactica 26 (2022): 23–35. http://dx.doi.org/10.15290/lingdid.2022.26.02.

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In this paper, we present the results of a study devoted to the analysis of the corpus, which consists of lexical diastratic material of a non-standard variety of the French language: about one hundred information sheets referred to as erotic biographies, which in turn seem to be the most noticeable example of the genre of external pornographic discourse today. In this case, these are biographies of X actors collected on the French-language website: https://www.videosxgays.com/. The analysis was based on the classification of Jean-Jacques Robrieux’s figures of discourse, focusing on the clearl

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Zhang, Weiqi, Jennifer Meyfeldt, Huabo Wang та ін. "β-Catenin mutations as determinants of hepatoblastoma phenotypes in mice". Journal of Biological Chemistry 294, № 46 (2019): 17524–42. http://dx.doi.org/10.1074/jbc.ra119.009979.

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Hepatoblastoma (HB) is the most common pediatric liver cancer. Although long-term survival of HB is generally favorable, it depends on clinical stage, tumor histology, and a variety of biochemical and molecular features. HB appears almost exclusively before the age of 3 years, is represented by seven histological subtypes, and is usually associated with highly heterogeneous somatic mutations in the catenin β1 (CTNNB1) gene, which encodes β-catenin, a Wnt ligand–responsive transcriptional co-factor. Numerous recurring β-catenin mutations, not previously documented in HB, have also been identifi

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Alessio, A., E. Pericuesta, I. Llamas-Toranzo, et al. "203 Genome Modifications by Sleeping Beauty Transposition and CRISPR/Cas9 to Improve Cow Milk Composition for Human Consumption." Reproduction, Fertility and Development 30, no. 1 (2018): 242. http://dx.doi.org/10.1071/rdv30n1ab203.

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Genome manipulation of cattle represents a powerful tool to increase the nutritional value and reduce allergenicity of cow milk for human consumption. This could be accomplished by improving the amount of polyunsaturated fatty acids (ω-3 and ω-6) and simultaneously abolishing β-lactoglobulin (BLG), a potent allergen for predisposed humans. The aim of this study was to introduce the sequence for a desaturase construct (mFAT-2, from C. elegans), which is able to catalyse the synthesis of ω-3 and ω-6 fatty acids, into the bovine genome by Sleeping Beauty (SB) transposition, and simultaneously kno

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Muenthaisong, S., O. Ujhelly, E. Varga, et al. "292 GENERATION OF MOUSE INDUCED PLURIPOTENT STEM CELLS FROM VARIOUS GENETIC BACKGROUND BY SLEEPING BEAUTY TRANSPOSON-MEDIATED GENE TRANSFER." Reproduction, Fertility and Development 23, no. 1 (2011): 243. http://dx.doi.org/10.1071/rdv23n1ab292.

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Induced pluripotent stem (iPS) cell technology allows the reprogramming of somatic cells to a pluripotent state; however, it requires viral gene transduction and permanent existence of the exogenous genes in the genome, which is a potential risk for abnormalities in the derived iPS cells. Recently, there was report that iPS cells have been made with piggyBack transposon. Here, we first reported that nonviral transfection of a Sleeping Beauty transposon, which comprises c-Myc, Klf-4, Oct3/4 (Pou5f1), and Sox-2, can reprogram mouse fibroblasts from 3 different genetic backgrounds: ICR (outbred),

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Zavala, I. Rubio, G. Martínez-Ales García, A. De Diego Cornejo, et al. "Psychotic episode during a travel to Saint-Petersburg. A variation of Stendhal Syndrome." European Psychiatry 41, S1 (2017): S518. http://dx.doi.org/10.1016/j.eurpsy.2017.01.681.

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IntroductionJourneys have been considered life-changing experiences since the first chronicles of humanity. Interest towards the relationship between travels and mental illness started off with the publication, in 1897, of Les aliénés voyageurs.Case reportWe report the case of a 52-year-old gentleman, married and without children, who works as a couch driver and has no past medical records. During a holiday trip, at his arrival to Saint Petersburg, he first experienced haze and cognitive and memory failures, along with malaise and sweating. The day after, while visiting the Hermitage museum, h

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Rozenberg, Natalia. "A NON-CLASSICAL CLASSIC, A LOOK AT THE ART OF S. ERZYA (1876-1959) FROM THE 21 ST CENTURY." Herald of Culturology, no. 3 (2021): 71–82. http://dx.doi.org/10.31249/hoc/2021.03.05.

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For the first time in Russian art history, the article attempts to show the integrity of the art of the Russian-Argentine sculptor S. Erzya on the basis of an art history analysis of his most famous works created in Italy, Russia and Argentina. The features of his personal and creative development are revealed in the context of socio-cultural events, which were distinguished by a stormy, sometimes catastrophic nature. The youthful ideals of Tolstoyism in the mind of a mature master acquire the features of a worldview that asserts the priority of the ideals of moral and spiritual perfection, th

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Hauschild-Quintern, J., B. Petersen, D. Herrmann, et al. "327 PRODUCTION OF TRIPLE TRANSGENIC hHO-1/GGTA-1–/–/hCD55 TRANSGENIC PIGS USING SLEEPING BEAUTY TRANSPOSITION AND ZINC-FINGER NUCLEASES." Reproduction, Fertility and Development 25, no. 1 (2013): 311. http://dx.doi.org/10.1071/rdv25n1ab327.

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Advances in xenotransplantation (pig-to-baboon or human transplantation) require multi-transgenic pigs with a homozygous knockout (KO) of the α1,3-galactosyltransferase gene (GGTA-1, encoding for Gal-epitopes) to control the hyperacute rejection response. To achieve prolonged survival of the porcine xenograft, transgenic expression of additional immune modulatory genes on the GGTA-1–/– background is considered the solution of choice. The acute vascular rejection (AVR) is primarily caused by endothelial cell activation and leads to rejection of GGTA-1–/– pig organs. Here, we set out to produce

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Petkov, S. G., W. A. Kues, and H. Niemann. "337 PROMOTER-DEPENDENT SILENCING OF REPROGRAMMING TRANSCRIPTION FACTORS IN MOUSE INDUCED PLURIPOTENT STEM CELLS PRODUCED WITH SLEEPING BEAUTY TRANSPOSON VECTORS." Reproduction, Fertility and Development 27, no. 1 (2015): 257. http://dx.doi.org/10.1071/rdv27n1ab337.

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Epigenetic silencing of the transgenes has been considered a prerequisite for complete reprogramming of mouse somatic cells to induced pluripotent stem cells (miPSC). Here, we examined the activity status of the reprogramming transcription factors in miPSC produced with Sleeping Beauty (SB) transposon vectors carrying expression cassettes with the porcine OCT4, SOX2, c-MYC, and KLF4 (pOSMK) under the control of doxycycline (DOX)-inducible (TetO) or constitutive (CAG) promoters. Mouse embryo fibroblasts (MEF) were electroporated with SB-TetO-rTA-SV40pA-TetO-pOSMK-IRES-tdTomato-bGHpA (TetO group

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Witalisz, Władysław. "“I cluppe and I cusse as I wood wore”: Erotic Imagery in Middle English Mystical Writings." Text Matters, no. 3 (November 1, 2013): 58–70. http://dx.doi.org/10.2478/texmat-2013-0026.

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The mutual influences of the medieval discourse of courtly love and the literary visions of divine love have long been recognized by readers of medieval lyrical poetry and devotional writings. They are especially visible in the affinities between the language used to construct the picture of the ideal courtly lady and the images of the Virgin Mary. Praises of Mary’s physical beauty, strewn with erotic implications, are an example of a strictly male eroticization of the medieval Marian discourse, rooted in Bernard of Clairvaux’s allegorical reading of the Song of Songs, where Mary is imagined a

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