Academic literature on the topic 'Somatomedin'

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Journal articles on the topic "Somatomedin"

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Dodson, M. V., B. A. Mathison, and K. L. Hossner. "Interaction of ovine somatomedin-C/IGF-I and IGF-I with specific IGF-I receptors on cultured muscle-derived fibroblasts." Acta Endocrinologica 116, no. 2 (1987): 186–92. http://dx.doi.org/10.1530/acta.0.1160186.

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Abstract. Binding of 125I-insulin-like growth factor-I and 125I-ovine somatomedin-C/IGF-I to monolayer cultures of muscle-derived ovine fibroblasts is described. Preliminary competitive binding experiments indicate that ovine fibroblasts possess independent cell surface receptors for IGF-I. Affinity of rIGF-II for IGF-I binding sites is minimal; rIGF-II binds to Type I IGF receptors at 1/1000 the strength of IGF-I. Insulin binds to the Type I IGF receptor at 1/100 the strength of IGF-I, whereas ovine somatomedin-C/IGF-I displays equivalent IGF-I binding as evidenced by overlapping competition
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Phillips, L. S., S. Goldstein, and J. R. Gavin. "Nutrition and somatomedin XVI: Somatomedins and somatomedin inhibitors in fasted and refed rats." Metabolism 37, no. 3 (1988): 209–16. http://dx.doi.org/10.1016/0026-0495(88)90097-2.

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UNTERMAN, LAWRENCE S., and STENVERT L. S. PHILLIPS. "Glucocorticoid Effects on Somatomedins and Somatomedin Inhibitors*." Journal of Clinical Endocrinology & Metabolism 61, no. 4 (1985): 618–26. http://dx.doi.org/10.1210/jcem-61-4-618.

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Phillips, Lawrence S., Vina R. Bajaj, Alan C. Fusco, Kim M. Keery, and Steven Goldstein. "Nutrition and somatomedin—XII. Fractionation of somatomedins and somatomedin inhibitors in normal and diabetic rats." International Journal of Biochemistry 17, no. 5 (1985): 597–603. http://dx.doi.org/10.1016/0020-711x(85)90291-5.

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Goldstein, S., and L. S. Phillips. "Nutrition and somatomedin: Nutritionally regulated release of somatomedins and somatomedin inhibitors from perfused livers in rats." Metabolism 38, no. 8 (1989): 745–52. http://dx.doi.org/10.1016/0026-0495(89)90060-7.

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Huybrechts, L. M., D. B. King, T. J. Lauterio, J. Marsh, and C. G. Scanes. "Plasma concentrations of somatomedin-C in hypophysectomized, dwarf and intact growing domestic fowl as determined by heterologous radioimmunoassay." Journal of Endocrinology 104, no. 2 (1985): 233–39. http://dx.doi.org/10.1677/joe.0.1040233.

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ABSTRACT The application of a human somatomedin-C radioimmunoassay for the determination of somatomedin-C in chicken plasma has been examined. Parallel inhibition of binding of 125I-labelled somatomedin-C to antisera raised against somatomedin-C was observed with acid-treated human and chicken plasma. The concentration of immunoreactive (IR)-somatomedin-C in the plasma of the domestic fowl appears to be GH dependent. Plasma concentrations of IR-somatomedin-C were reduced after hypophysectomy and partially restored by replacement therapy with chicken GH. The age/development pattern of circulati
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Pavelić, K., D. Vrbanec, S. Marušić, S. Levanat, and T. Čabrijan. "Autocrine tumour growth regulation by somatomedin C: an in-vitro model." Journal of Endocrinology 109, no. 2 (1986): 233–38. http://dx.doi.org/10.1677/joe.0.1090233.

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ABSTRACT A human primary haemangiosarcoma was derived from a patient with severe hypoglycaemia. Cell line established from that tumour secreted somatomedin C in serum-free culture media. Immunoreactive somatomedin from the media eluted from Sephacryl S-200 in two peaks of 160 000 and 8000 molecular weights. Similar results were obtained when medium was acidified and chromatographed on Sephadex G-50. Binding of tracer concentrations of 125I-labelled somatomedin C to human haemangiosarcoma cells was much higher than that of 125I-labelled insulin. Half-maximal displacement of 125I-labelled somato
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Phillips, Lawrence S., Alan C. Fusco, and Terry G. Unterman. "Nutrition and somatomedin. XIV. Altered levels of somatomedins and somatomedin inhibitors in rats with streptozotocin-induced diabetes." Metabolism 34, no. 8 (1985): 765–70. http://dx.doi.org/10.1016/0026-0495(85)90028-9.

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Ronge, H., J. Blum, C. Clement, F. Jans, H. Leuenberger, and H. Binder. "Somatomedin C in dairy cows related to energy and protein supply and to milk production." Animal Science 47, no. 2 (1988): 165–83. http://dx.doi.org/10.1017/s000335610000324x.

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ABSTRACTSomatomedin C and other hormones, as well as blood metabolites, were measured during the dry period and during lactation in dairy cows, given different amounts of energy and protein, to study metabolic and endocrine adaptations. Somatomedin C, specifically measured by radioimmunoassay after separation from its binding protein, did not exhibit typical diurnal variations, in contrast to somatotropin and insulin, which increased particularly after concentrate intake. Somatomedin C markedly decreased at parturition and reached lowest values around the peak of lactation, while levels of som
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Burch, W. M., and J. J. Van Wyk. "Triiodothyronine stimulates cartilage growth and maturation by different mechanisms." American Journal of Physiology-Endocrinology and Metabolism 252, no. 2 (1987): E176—E182. http://dx.doi.org/10.1152/ajpendo.1987.252.2.e176.

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The mechanisms by which triiodothyronine (T3) stimulates growth and maturation of growth-plate cartilage in vitro were studied by incubating embryonic chick pelvic cartilages in serum-free medium in the presence and absence of T3 for 3 days. To determine whether T3 might stimulate production of somatomedins by the cartilage, medium from cartilage incubated with and without T3 was assayed for somatomedin C (Sm-C) by radioimmunoassay. No difference in Sm-C content was found. However, cartilage incubated with T3 and increasing amounts of human Sm-C (0.5-20 ng/ml) weighed more and had greater amou
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Dissertations / Theses on the topic "Somatomedin"

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Bastian, Susan Elaine Putnam. "Transcellular transport of insulin-like growth factor-1 (IGF-1)." Title page, contents and abstract only, 1997. http://web4.library.adelaide.edu.au/theses/09PH/09phb3255.pdf.

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Bagley, Christopher James. "Analogues of Insulin-Like Growth Factor-1 / Christopher James Bagley." Title page, table of contents and summary only, 1989. http://web4.library.adelaide.edu.au/theses/09PH/09phb146.pdf.

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Williams, Nolann G. "Myostatin regulation of the insulin-like growth factor axis." Pullman, Wash. : Washington State University, 2009. http://www.dissertations.wsu.edu/Thesis/Spring2009/n_williams_042009.pdf.

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Thesis (M.S. in genetics and cell biology)--Washington State University, May 2009.<br>Title from PDF title page (viewed on Apr. 5, 2010). "School of Molecular Biosciences." Includes bibliographical references (p. 39-45).
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Ramaswamy, Girish. "Mechanical and geometric characterization of mouse cortical bone with osteoblast-specific knockout of insulin-like growth factor receptor gene." Birmingham, Ala. : University of Alabama at Birmingham, 2007. https://www.mhsl.uab.edu/dt/2009r/ramaswamy.pdf.

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Diego, Vincent P. "Genotype x age interaction, and the insulin-like growth factor I axis in the San Antonio Family Heart Study a study in human senescence /." Diss., Online access via UMI:, 2005.

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Wilker, Erik William. "Role of insulin-like growth factor I in mouse skin tumor promotion /." Full text (PDF) from UMI/Dissertation Abstracts International, 2001. http://wwwlib.umi.com/cr/utexas/fullcit?p3064687.

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Dodson, Michael Verne. "EFFECTS OF INSULIN AND INSULIN-LIKE GROWTH FACTORS ON SATELLITE CELL PROLIFERATION IN VITRO (SOMATOMEDINS, RECEPTORS)." Diss., The University of Arizona, 1985. http://hdl.handle.net/10150/188065.

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Primary cultures of skeletal muscle satellite cells were induced to proliferate by exposure to physiologic levels of somatomedins and pharmacologic levels of insulin. Dexamethasone inclusion in serum containing medium facilitated the ovine somatomedin (oSm) (P < 0.05), but that both were different than the proliferation induced by MSA/rIGF-II (P < 0.05). In the presence of insulin concentrations that promote maximum proliferation, addition of oSm did not produce an additive effect, whereas the addition of MSA/rIGF-II did produce a significant increase in satellite cell proliferation above that
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Conlon, Michael Allan. "The effects of chronic IGF-I, IGF-II on long R3 IGF-I infusion on the postnatal growth of rats and guinea pigs." Title page, contents and abstract only, 1995. http://web4.library.adelaide.edu.au/theses/09PH/09phc7518.pdf.

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Thornton, William H. "The role of extracellular zinc in IGF-1 receptor expression and proliferation in a normal and squamous cell carcinoma cell line." free to MU campus, to others for purchase, 1999. http://wwwlib.umi.com/cr/mo/fullcit?p9946305.

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涂文偉 and Wenwei Tu. "Effects of insulin-like growth factor 1 on cord blood T cell development." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B31239377.

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Books on the topic "Somatomedin"

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N, Schofield Paul, ed. The Insulin-like growth factors: Structure and biological functions. Oxford University Press, 1992.

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1945-, LeRoith Derek, Zumkeller Walter, and Baxter R. C, eds. Insulin-like growth factors. Eurekah.com, Landes Bioscience, 2003.

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International Symposium on Insulin-Like Growth Factors/Somatomedins (2nd 1991 San Francisco, Calif.). Modern concepts of insulin-like growth factors: Proceedings of the Second International Symposium on Insulin-Like Growth Factors/Somatomedins held January 12-16, 1991 in San Francisco, California. Elsevier, 1991.

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E, Müller E., Cocchi Daniela, and Locatelli Vittorio 1949-, eds. Growth hormone and somatomedins during lifespan. Springer-Verlag, 1993.

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Laboratories, Ross, ed. Somatomedins and other peptide growth factors--relevance to pediatrics: Report of the Eighty-ninth Ross Conference on Pediatric Research. Ross Laboratories, 1985.

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Hildahl, Jon. Endocrine regulation of flatfish metamorphosis: Growth hormone, insulin-like growth factor-I and their receptors in Atlantic halibut. Göteborg University, Department of Zoology/Zoophysiology, 2007.

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Hildahl, Jon. Endocrine regulation of flatfish metamorphosis: Growth hormone, insulin-like growth factor-I and their receptors in Atlantic halibut. Göteborg University, Department of Zoology/Zoophysiology, 2007.

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Johansson, Anna G. Clinical studies on the role of growth hormone and insulin-like growth factor I in bone metabolism. Acta Universitatis Upsaliensis, 1995.

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K, Raizada Mohan, Phillips M. Ian, and LeRoith Derek 1945-, eds. Insulin, insulin-like growth factors, and their receptors in the central nervous system. Plenum Press, 1987.

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Reiss, Krzysztof. Insulin-like growth factor-1 and cellular adaptations of ventricular myocytes in pathologic heart. Wydawn. Uniwersytetu Jagiellońskiego, 1997.

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Book chapters on the topic "Somatomedin"

1

Phillips, L. S., S. Goldstein, and J. D. Klein. "Somatomedin Inhibitors." In Molecular and Cellular Biology of Insulin-like Growth Factors and Their Receptors. Springer US, 1989. http://dx.doi.org/10.1007/978-1-4684-5685-1_7.

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Kaplowitz, Paul B., and Steven D. Chernausek. "Somatomedin Receptors." In Peptide Hormone Receptors, edited by M. Y. Kalimi and J. R. Hubbard. De Gruyter, 1987. http://dx.doi.org/10.1515/9783110850246-011.

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Hoffman, Andrew R., Susan N. Perkins, Ines Zangger, et al. "Somatomedin Gene Expression." In Acromegaly. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4613-1913-9_6.

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Hintz, Raymond L. "The Somatomedin Binding Proteins." In Human Growth Hormone. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4615-7201-5_44.

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Pòvoa, G., K. Hall, and V. P. Collins. "Studies on somatomedin binding protein." In Advances in Growth Hormone and Growth Factor Research. Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-662-11054-6_8.

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Phillips, L. S., and T. G. Unterman. "Increased Somatomedin Inhibitors in Renal Failure." In Human Growth Hormone. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4615-7201-5_46.

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Underwood, Louis E., Eric P. Smith, Judson J. Van Wyk, et al. "Somatomedin C/Insulinlike Growth Factor I." In Human Growth Hormone. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4615-7201-5_49.

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Li, Choh Hao. "Synthetic Somatomedin C/Insulinlike Growth Factor I." In Human Growth Hormone. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4615-7201-5_41.

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Rosenfeld, Ron G., Gian Paolo Ceda, Darrell M. Wilson, and Andrew R. Hoffman. "Somatomedin Action and Tissue Growth Factor Receptors." In Acromegaly. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4613-1913-9_7.

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Nissley, S. Peter, Lynne A. Gaynes, and Robert M. White. "Somatomedin/Insulinlike Growth Factor in the Human Fetus." In Human Growth Hormone. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4615-7201-5_50.

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Conference papers on the topic "Somatomedin"

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Wasi, S., P. Alles, D. Gauthier, et al. "STUDIES ON SMALL MOLECULAR WEIGHT ADHESION PROTEINS (SAPs) FROM CONNECTIVE TISSUES." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643556.

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We have identified a family of low molecular weight proteins with cell attachment properties in a variety of soft and mineralised connective tissues (Wong et al., Biochem. J. 232, 119, 1985). For further characterisation of these proteins we extracted porcine bones with 4 M guanidine hydrochloride and purified the proteins on a series of gel filtration columns The purifed SAPs comprise three bands with Mr -14 000 -17 000. All three proteins bound to heparin-sepahrose in both the presence and absence of 4M urea, and when eluted with 2 M NaCl they retained their cell binding capacity. These prot
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Kostecká, Zuzana, and Ján Blahovec. "Binding proteins of somatomedins and their biological effects. A minireview." In VIth Conference Biologically Active Peptides. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 1999. http://dx.doi.org/10.1135/css199903028.

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