Relevant bibliographies by topics / Somatostatin analog

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Somatostatin analog'

Author: Grafiati
Published: 5 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "Somatostatin analog"

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Chisholm, Connie, and Gordon R. Greenberg. "Somatostatin-28 regulates GLP-1 secretion via somatostatin receptor subtype 5 in rat intestinal cultures." American Journal of Physiology-Endocrinology and Metabolism 283, no. 2 (2002): E311—E317. http://dx.doi.org/10.1152/ajpendo.00434.2001.

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Five somatostatin receptors (SSTRs) bind somatostatin-14 (S-14) and somatostatin-28 (S-28), but SSTR5 has the highest affinity for S-28. To determine whether S-28 acting through SSTR5 mediates inhibition of glucagon-like peptide-1 (GLP-1), fetal rat intestinal cell cultures were treated with somatostatin analogs with relatively high specificity for SSTRs 2–5. S-28 dose-dependently inhibited GLP-1 secretion stimulated by gastrin-releasing peptide more potently than S-14 (EC50 0.01 vs. 5.8 nM). GLP-1 secretion was inhibited by an SSTR5 analog, BIM-23268, more potently than S-14 and nearly as eff
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Vitale, Giovanni, Alessandra Dicitore, Concetta Sciammarella, et al. "Pasireotide in the treatment of neuroendocrine tumors: a review of the literature." Endocrine-Related Cancer 25, no. 6 (2018): R351—R364. http://dx.doi.org/10.1530/erc-18-0010.

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Somatostatin analogs have an important role in the medical therapy of neuroendocrine tumors (NETs). Octreotide and lanreotide, both somatostatin analogs binding with high affinity for the somatostatin receptor (SSTR)2, can control symptoms in functional NETs. In addition, these compounds, because of their antiproliferative effects, can stabilize growth of well-differentiated NETs. Pasireotide is a novel multireceptor-targeted somatostatin analog with high affinity for SSTR1, 2, 3, and 5. This review provides an overview of the state of the art of pasireotide in the treatment of NETs, with the
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Lamberts, Steven W. J. "Non-pituitary actions of somatostatin. A review on the therapeutic role of SMS 201-995 (sandostatin)." Acta Endocrinologica 113, no. 2_Suppla (1986): S41—S55. http://dx.doi.org/10.1530/acta.0.111s0041.

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Abstract. Natural Somatostatin has a short half-life (3 min), is only active after intravenous administration and causes a rebound hypersecretion of hormones after discontinuation of administration. Recently a longacting powerful Somatostatin analog was developed (SMS 201-995; Sandostatin) which has a half-life of 113 min after subcutaneous administration. After administration of this analog no rebound hypersecretion of hormones was observed. In the present review the effects of the acute administration and of long-term treatment with SMS 201-995 in acromegalic patients is discussed. In additi
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Gezer, Emre, Yeliz Demirhan, Alev Selek, et al. "Comparison between somatostatin analog injections." Revista da Associação Médica Brasileira 68, no. 4 (2022): 514–18. http://dx.doi.org/10.1590/1806-9282.20211224.

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Longnecker, Stephen M. "Somatostatin and Octreotide: Literature Review and Description of Therapeutic Activity in Pancreatic Neoplasia." Drug Intelligence & Clinical Pharmacy 22, no. 2 (1988): 99–106. http://dx.doi.org/10.1177/106002808802200201.

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The somatostatins represent endogenous substances that serve a diversity of functions in the body. These activities are just beginning to be understood and could have major implications in the treatment of human disease. Their chief pharmacologic activities lie in the modification or modulation of protein hormone synthesis of the gastrointestinal system; a great many other systems may be involved as well. Since the discovery of the therapeutic potentials of naturally isolated somatostatins, attempts have been made to design newer analogs more conducive to practical use. Such an example is long
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Gaumann, D. M., T. S. Grabow, T. L. Yaksh, S. J. Casey, and M. Rodriguez. "Intrathecal somatostatin, somatostatin analogs, substance P analog and dynorphin A cause comparable neurotoxicity in rats." Neuroscience 39, no. 3 (1990): 761–74. http://dx.doi.org/10.1016/0306-4522(90)90259-7.

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Sanarova, E. V., Zhang Xi, M. V. Dmitrieva, et al. "FEATURES OF THE TECHNOLOGY OF LIPOSOMAL FORMULATION OF A ANALOGUE HYPOTHALAMIC HORMONE SOMATOSTATIN." Russian Journal of Biotherapy 15, no. 4 (2016): 78–84. http://dx.doi.org/10.17650/1726-9784-2016-15-4-78-84.

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Background. In connection with the prospect of the use of an analog of the hypothalamic hormone somatostatin synthesized by the laboratory of chemical synthesis Institute of experimental diagnostics and chemotherapy of FSBI «N.N. Blokhin Russian Cancer Research Center» and showed a high anti-tumor activity as a drug arises a need to establish an optimal technology of its receipt. In preliminary studies in a modelformulation for an analog of the hypothalamic hormone somatostatin selected liposome technological process of which has a series of specific steps comprising. Objective. Development of
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Hidayatullah, Rian, Hendra Budiawan, Budi Darmawan, and Erwin Affandi. "Somatostatin." Unram Medical Journal 10, no. 2 (2021): 468–79. http://dx.doi.org/10.29303/jku.v10i2.482.

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Somatostatin, also known as growth hormone-inhibiting factor (GIF) or somatotropin release-inhibiting factor (SRIF), is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation. Somatostatin can be regarded as secretory pan-inhibitory,because it can inhibit secretion of almost all endocrine and exocrine glands. Somatostatin has 2 active forms (somatostatin-14 and 28), but the short half-life of the hormone was one of the reasons why the native hormone was not feasible for routine clinical practice. Somatostatin analog was synthesized for the fi
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Marazuela, M., A. E. Paniagua, M. D. Gahete, et al. "Somatotroph Tumor Progression during Pegvisomant Therapy: A Clinical and Molecular Study." Endocrinology 151, no. 12 (2010): 5974. http://dx.doi.org/10.1210/endo.151.12.9997.

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Context: There is concern that pegvisomant could be associated with a higher risk of tumor growth. The rate and possible determinants of this tumor growth are unknown. Objective: The objective of the study was to investigate the clinical, immunohistological, and molecular factors conditioning tumor growth in patients taking pegvisomant. Design and Setting: This was a cross-sectional study performed from 2004 to 2010 in four university hospitals in Spain. Patients: Seventy-five acromegalic patients with active disease resistant to somatostatin analogs treated with pegvisomant were followed up f
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Katz, Michael D., Brian L. Erstad, and Cathryn Rose. "Treatment of Severe Cryptosporidium-Related Diarrhea with Octreotide in a Patient with AIDS." Drug Intelligence & Clinical Pharmacy 22, no. 2 (1988): 134–36. http://dx.doi.org/10.1177/106002808802200206.

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Cryptosporidiosis commonly causes severe diarrhea in immunosuppressed patients. There currently are no antiparasitic drugs consistently effective for this infection. This case describes a 26-year-old hemophiliac patient with acquired immunodeficiency syndrome and cryptosporidiosis whose diarrhea improved with continuous intravenous administration of a long-acting somatostatin analog, octreotide. Somatostatin has a variety of inhibitory effects on gastrointestinal hormones as well as a possible nonspecific effect on gastrointestinal mucosal fluid and electrolyte secretion. The somatostatin anal
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Dissertations / Theses on the topic "Somatostatin analog"

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Li, Su-Chen. "Small Intestinal Neuroendocrine Tumor Analyses : Somatostatin Analog Effects and MicroRNA Profiling." Doctoral thesis, Uppsala universitet, Endokrin Onkologi, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-233207.

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Small intestinal neuroendocrine tumors (SI-NETs) originate from serotonin-producing enterochromaffin (EC) cells in the intestinal mucosa. Somatostatin analogs (SSAs) are mainly used to control hormonal secretion and tumor growth. However, the molecular mechanisms leading to the control of SI-NETs are unknown. Although microRNAs (miRNAs) are post transcriptional regulators deeply studied in many cancers, are not well-defined in SI-NETs. We adopted a two-pronged strategy to investigate SSAs and miRNAs: first, to provide novel insights into how SSAs control NET cells, and second, to identify an e
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Verchere, Cameron Bruce. "Control of insulin secretion from the perfused rat pancreas : effects of acetylcholine and a somatostatin analog, SMS 201-995." Thesis, University of British Columbia, 1987. http://hdl.handle.net/2429/26657.

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The effect of varying concentrations of glucose or the gastrointestinal hormones, gastric inhibitory polypeptide (GIP) and somatostatin (SS-14), on the in vitro immunoreactive insulin (IRI) response to the parasympathetic neurotransmitter, acetylcholine (ACh) was investigated. The isolated, vascularly perfused rat pancreas was used in all experiments. Acetylcholine (1.0 µM) did not stimulate IRI secretion in the presence of 2.2 mM glucose. However, in the presence of 4.4, 6.6, or 8.9 mM glucose, ACh (1.0 µM) potently stimulated IRI secretion (approximately fourfold). At a higher glucose conce
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Assaka, Lucien. "Etude biochimique d'une (ou de) substances(s) immunologiquement apparentée(s) à la somatostatine chez l'escargot Helix aspersa : Corrélations avec la croissance et la regénération de la coquille." Besançon, 1988. http://www.theses.fr/1988BESA2022.

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Mise en evidence par immunocytochimie d'une substance analogue a la somatostatine dans le cerveau, l'hepatopancreas et le bord du manteau d. H. A. Des techniques biochimiques complementaires montrent l'existence de plusieurs substances differentes. La quantite de ces substances est plus elevee chez les animaux juveniles et a croissance lente, surtout localisees a l'hepatopancreas. Ces substances sont un relais ou un facteur de regulation de la croissance et de la regeneration de la coquille
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Cheng, Zhen. "Rhenium cyclized [alpha]-MSH analogs, somatostatin analogs and T-antigen avid peptides as imaging and therapeutic agents for tumor targeting /." free to MU campus, to others for purchase, 2001. http://wwwlib.umi.com/cr/mo/fullcit?p3012959.

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Morange, Isabelle. "Etude de l'efficacite et de la tolerance d'un analogue retard de la somatostatine (somatuline) dans l'acromegalie evolutive." Aix-Marseille 2, 1992. http://www.theses.fr/1992AIX20833.

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Rouah, Rosilio Myriam. "Traitement au long cours de l'acromegalie par la sandostatine." Aix-Marseille 2, 1990. http://www.theses.fr/1990AIX20816.

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BABIN, THIERRY. "Traitement de l'acromegalie par un analogue de la somatostatine, la sms 201-995, administratree en injection sous-cutanee continue." Toulouse 3, 1988. http://www.theses.fr/1988TOU31174.

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ROUX, LAURENCE. "Place actuelle de la sandostatine dans le traitement de l'acromegalie : a propos de 10 cas." Besançon, 1992. http://www.theses.fr/1992BESA3094.

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Ginj, Mihaela. "Design, synthesis and evaluation of somatostatin analogs for improved imaging and radionuclide therapy /." Basel : [s.n.], 2005. http://edoc.unibas.ch/diss/DissB_7345.

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Plöckinger, Ursula. "Akromegalie." Doctoral thesis, Humboldt-Universität zu Berlin, Medizinische Fakultät - Universitätsklinikum Charité, 2001. http://dx.doi.org/10.18452/13753.

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Die Akromegalie - Folge eines Wachstumshormon (STH) sezernierenden Hypophysentumors - ist eine seltene Erkrankung. Bei früher Diagnose ist die Akromegalie gut behandelbar. Unbehandelt - oder zu spät behandelt - führt sie zu hoher Co-Morbidität und verkürzt das Leben. Endokrinologische Therapieziele wurden kürzlich definiert: Heilung bei STH<br>Acromegaly, caused by a growth hormone (GH)-secreting pituitary adenoma, is a rare disease. If diagnosed early therapeutic results are good. However, untreated or treated belatedly, acromegaly is associated with a high co-morbidity and reduced life-expec
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Books on the topic "Somatostatin analog"

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Scarpignato, Carmelo. Somatostatin analogs in cancer management. Karger, 2001.

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M, Pawlikowski, ed. Somatostatin analogs in diagnostics and therapy. Landes Bioscience, 2007.

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Pawlikowski, M. Somatostatin analogs in diagnostics and therapy. Landes Bioscience, 2007.

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Weiss, Tilla. Wirkungen von Somatostatin und Somatostatin-Analoga auf Funktionen von Leber und Gallenwegen. [s.n.], 1991.

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Hubalewska-Dydejczyk, Alicja. Somatostatin analogues: From research to clinical practice. Wiley, 2015.

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1946-, Hoffken K., and Kath R. 1957-, eds. Peptides in oncology III: Somatostatin and LH-RH analogues. Springer, 2000.

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J, Lamberts Steven W., ed. Sandostatin in the treatment of acromegaly: Consensus round table, Amsterdam, 1987. Springer-Verlag, 1988.

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Bhayana, Shelly. The implication of somatotroph adenoma phenotype to somatostatin analog responsiveness in acromegaly. 2006.

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Pawlikowski, Marek. Somatostatin Analogs in Diagnostics and Therapy. Taylor & Francis Group, 2007.

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Pawlikowski, Marek. Somatostatin Analogs in Diagnostics and Therapy. Taylor & Francis Group, 2007.

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Book chapters on the topic "Somatostatin analog"

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Williams, Gareth, John V. Anderson, and Stephen R. Bloom. "Treatment of Gut-Associated Neuroendocrine Tumors with the Long-Acting Somatostatin Analog, SMS 201-995." In Somatostatin. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-5326-3_36.

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del Pozo, E., S. W. J. Lamberts, C. Sieber, and A. Gomez-Pan. "Effect of a Long-Acting Somatostatin Analog (Sms 201–995) on Glucose Homeostasis in Type I Diabetes and in Acromegaly." In Somatostatin. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-5326-3_29.

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Erchegyi, Judit, Carl Hoeger, Sandra Wenger, et al. "N-Methyl Scan of a sst1-Selective Somatostatin (SRIF) Analog." In Peptides: The Wave of the Future. Springer Netherlands, 2001. http://dx.doi.org/10.1007/978-94-010-0464-0_335.

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Kéri, Gy, T. Vántus, A. Horváth, et al. "Mechanism of action of a tumor-selective somatostatin analog: TT-232." In Peptides 1994. Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-011-1468-4_54.

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Tatsi, Aikaterini, Berthold A. Nock, Theodosia Maina, and Marion de Jong. "Somatostatin Analogs." In Somatostatin Analogues. John Wiley & Sons, Inc, 2015. http://dx.doi.org/10.1002/9781119031659.ch26.

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Baxter, J. N., S. A. Jenkins, and R. Shields. "Somatostatin and Analogs in the Management of Variceal Hemorrhage." In Somatostatin. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-5326-3_32.

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Jackson, I. M. D., L. Barnard, W. Cobb, M. Hein, and R. Perez. "Long-Term Treatment of Resistant Acromegaly with a Somatostatin Analog (SMS 201–995, Sandostatin®)." In Sandostatin® in the Treatment of Acromegaly. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-73694-0_20.

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Nutt, Ruth F., C. Dylion Colton, Richard Saperstein, and Daniel F. Veber. "Side Chain Conformations of Somatostatin Analogs when Bound to Receptors." In Somatostatin. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-5326-3_8.

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Padberg, W. M., H. Morgalla, P. Hild, and K. Schwemmle. "Immunsuppressive Wirkung von Somatostatin und dem Somatostatin-Analog SMS 201–995 sowie ihr immunsuppressiver synergistischer Effekt mit low-dose Cyclosporin A in der Organtransplantation." In 107. Kongreß der Deutschen Gesellschaft für Chirurgie Berlin, 17.–21. April 1990. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-75576-7_19.

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Albert, R., B. Stolz, P. Smith-Jones, Ch Bruns, H. Knecht, and H. Mäcke. "[67/68Ga]-Deferoxamine-octreotide, potential somatostatin analog for tumor imaging and PET: Synthesis and biological profile." In Peptides 1992. Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-1470-7_41.

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Conference papers on the topic "Somatostatin analog"

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Azhdarinia, Ali. "Development, optimization, and preclinical feasibility of a fluorescent somatostatin analog for intraoperative imaging in neuroendocrine tumors." In Molecular-Guided Surgery: Molecules, Devices, and Applications XI, edited by Summer L. Gibbs and Kenneth M. Tichauer. SPIE, 2025. https://doi.org/10.1117/12.3048003.

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Edwards, W. Barry, Kexian Liang, Baogang Xu, Carolyn J. Anderson, and Samuel Achilefu. "Synthesis and radiolabeling of a somatostatin analog for multimodal imaging." In Biomedical Optics 2006, edited by Samuel Achilefu, Darryl J. Bornhop, and Ramesh Raghavachari. SPIE, 2006. http://dx.doi.org/10.1117/12.648096.

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Petrou, Christos, Anastasia Nikolopoulou, Vassiliki Magafa, Berthold Nock, Theodosia Maina, and Paul Cordopatis. "Synthesis and preliminary biological evaluation of a cyclic somatostatin analog with high affinity to sst1–5." In IXth Conference Biologically Active Peptides. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2005. http://dx.doi.org/10.1135/css200508059.

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Axelrod, D., J. Smith, B. Singh, W. Ruan, S. Lubitz, and D. Kleinberg. "Breast Cancer Chemoprevention in Pre-Neoplastic Lesions with a Somatostatin Analog in Nine Women: A Proof of Principle Trial." In Abstracts: Thirty-Second Annual CTRC‐AACR San Antonio Breast Cancer Symposium‐‐ Dec 10‐13, 2009; San Antonio, TX. American Association for Cancer Research, 2009. http://dx.doi.org/10.1158/0008-5472.sabcs-09-1044.

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Rick, Ferenc G., Andrew Abi-Chaker, Luca Szalontay, Norman L. Block, Gabor Halmos, and Andrew V. Schally. "Abstract 2125: AN-162, a targeted cytotoxic analog of somatostatin, suppresses growth of human hormone refractory prostate cancers in vitro and in vivo." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-2125.

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Eschbach, R. S., M. Hofmann, L. Späth, et al. "Comparison of somatostatin receptor expression in patients with neuroendocrine tumours with and without somatostatin analogue treatment imaged with [18F]SiTATE." In 60. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin. Georg Thieme Verlag KG, 2022. http://dx.doi.org/10.1055/s-0042-1746068.

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Ahenkorah, Stephen, Erica Murce, Cawthorne Christopher, et al. "3p-C-NETA-TATE: A Potential Somatostatin Analogue for Diagnostic and Therapeutic SSTR2 Targeting Radiopharmaceuticals." In Abstracts for the 18th International Conference on Radiopharmaceutical Therapy (ICRT). Thieme Medical and Scientific Publishers Pvt. Ltd., 2023. http://dx.doi.org/10.1055/s-0043-1769961.

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Pusceddu, Sara, Roberto Buzzoni, Laura Concas, et al. "Abstract 1189: The impact of metformin on progression-free survival in patients with advanced pancreatic well differentiated neuroendocrine tumor receiving everolimus plus somatostatin analogue treatment." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-1189.

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Reports on the topic "Somatostatin analog"

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Zamora, P. O., H. Bender, H. J. Biersack, and F. F. Jr Knapp. Interim report on intrathoracic radiotherapy of human small-cell lung carcinoma in nude mice with Re-188-RC-160, a radiolabeled somatostatin analogue. Office of Scientific and Technical Information (OSTI), 1995. http://dx.doi.org/10.2172/87003.

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