Relevant bibliographies by topics / Somnifera Root Extract

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers
  5. Reports

Academic literature on the topic 'Somnifera Root Extract'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Somnifera Root Extract"

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Abu Zaid, Mohammad, Maheshwar Chauhan, and Swarndeep Chauhan. "Protective role of Withania somnifera root extract on lipid peroxidation of Erythrocytes." Universities' Journal of Phytochemistry and Ayurvedic Heights II, no. 33 (2022): 1–8. http://dx.doi.org/10.51129/ujpah-2022-33-2(1).

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Withania Somnifera (Ashwagandha) is an important medicinal plant that has been used in Ayurvedic and indigenous medicine. It is also known as Indian ginseng. It exerts antioxidant, anti-inflammatory and immune modulatory activities. In the present study, we studied the free radical scavenging activity of Withania Somnifera root extract. The radical scavenging effect of the extract was studied by its effect on hydroxy radicals generated by Fe-ascorbate-H2O2 system. Our results showed that Withania Somnifera root extract (1-10,000 µg/ ml) resulted in a significant dose dependent increase in perc
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Devaraj Reddy KN, Srilakshmi Aluri, Prathvi Shetty, et al. "Assessing the Efficacy and Biological Benefits of Withanolide-rich Withania somnifera Root Extract." Annual Research & Review in Biology 39, no. 5 (2024): 54–64. http://dx.doi.org/10.9734/arrb/2024/v39i52081.

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The medicinal plant Withania somnifera, usually referred to as Ashwagandha, is a member of the Solanaceae family. The presence of Withanolides in the roots is responsible for a number of pharmacological effects in Ashwagandha. Withanolides have been demonstrated to be an effective neuronal, immune, anti-stress, and anti-cancer agent. However, Withanolides demonstrated limited permeability, lowering the bioavailability and efficacy of active compounds. The goal of the study was to ascertain the biological efficacy of Ashwagandha Composition, a blend of W. somnifera milk extract and water extrac
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Kumar, Ravi, Rajat Dhariwal, Anurag Kumar, and Miss Minata. "Effect of Withania Somnifera (L.) root extract\'s on PC12 induced by hydrogen peroxide, study." Journal of Pharmaceutical and Biological Sciences 10, no. 2 (2023): 79–82. http://dx.doi.org/10.18231/j.jpbs.2022.015.

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The L. is also used as a crude medicament that mostly effected in various neurological and immunological disorders. It is also known as Ashwagandha and “Indian ginseng” in Indian region. There is a lack of information on the possible neuroprotective properties of W. somnifera root against HO- and Ab(1-42)-induced cytotoxicity, which are now targeted for innovative treatments for dementia, particularly dementia of the Alzheimer's type (AD). According to this research, we prepared an aqueous extract of dried roots of W. somnifera that possess the protective effect against Ab- aggregated fibril a
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Hammood, Mahmood Neamah, Liqaa Hasson Saqban, and Nazar Jebar Metib. "Protective Role of Withania somnifera Against the Adverse Effects of Levofloxacin on Testes Tissue of Rats In Vivo." Medical Journal of Babylon 22, no. 1 (2025): 41–49. https://doi.org/10.4103/mjbl.mjbl_174_23.

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Abstract Background: Medicinal plants have many uses in traditional medicine in all cultures due to their unique therapeutic properties. Withania somnifera is considered an agent to improve sexual health, an antioxidant, anti-aging, and anti-inflammatory. Objective: This study aimed to determine the therapeutic effect of W. somnifera on the potential Levofloxacin-induced testicular injury in rats. Materials and Methods: Thirty adult male Wistar rats were randomly divided into five groups: control group (C), saline-treated for 60 days. Group (W) W. somnifera root extract was orally treated for
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Sharma, Mamta, Rupinder Kaur, and Sunil Puri. "BIO-HERBICIDAL EFFICIENCY OF WITHANIA SOMNIFERA AGAINST IMPORTANT HIMALAYAN WEEDS." International Journal of Pharmacy and Pharmaceutical Sciences 9, no. 3 (2017): 88. http://dx.doi.org/10.22159/ijpps.2017v9i3.14740.

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Objective: The aim of the study was to evaluate the bioherbicidal activity of Withania somnifera against germination and growth of noxious weeds of Himalaya i.e. Ageratum coenyzoides, Chenopodium album and Achyranthus aspera in a laboratory and foliar spray bioassay which will act as a tool of weed management in the Himalayan region.Methods: Root, stem and leaf aqueous extract of Withania somnifera at 100% concentration were applied to determine their effect on the seed germination and seedling growth of tested weeds under laboratory condition. Foliar spray bioassay was carried out by spraying
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Anni, Anni. "Phytochemical Profiling of Withania somnifera for Qualitative and Quantitative Study of Bioactive Component Withaferin a by High-Performance Liquid Chromatography." Bioscience Biotechnology Research Communications 18, no. 1 (2025): 67–71. https://doi.org/10.21786/bbrc/18.1.10.

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Over the past few years, the attention of people has changed from man-made (synthetic) to natural medicines. Withania somnifera’s phytochemical analysis has identified the presence of withanolides, which are pharmacologically active steroidal lactones. The two main withanolides that were isolated from Withania somnifera in India were withanolide D and withaferin A, both of which demonstrated cytotoxic and anticancer effects. The present investigation aimed to evolve a standard phytochemical profiling of Withania somnifera for the presence of withaferin A. The dried root sample was minced and g
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Bhattacharjee, Piyasi. "Effects of cold stress, alprazolam and phytomedicine in combination with stress on blood glucose and haematogical parameter of the male albino rat." INTERNATIONAL JOURNAL OF EXPERIMENTAL RESEARCH AND REVIEW 22 (2020): 37–44. http://dx.doi.org/10.52756/ijerr.2020.v22.005.

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The present study conducted to investigate the haematological changes and changes of blood glucose level in male albino rat due to cold stress. In this experiment normal 12:12 light dark phases were maintained for all the groups. Control group was kept at normal room temperature (22 ± 1). A (4°C), B in (0°C), C (4°C and 0.30 mg alprazolam / kg body weight /animal), D (0°C and 0.30 mg alprazolam/ kg body weight/ animal. E2 group was treated with (4°C and 1000 mg/kg body weight methanolic extract of Withania somnifera root extract /animal). F2 group was treated with (0°C and 1000 mg/kg body weig
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Tebeka Simur, Tesfaye. "Phytochemical Investigation and Antioxidant Activity of Leaf Extract of Withania somnifera from Konso, South Ethiopia." Oriental Journal of Chemistry 34, no. 4 (2018): 1824–31. http://dx.doi.org/10.13005/ojc/3404016.

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Withania somnifera is endemic to Ethiopia where its leaf and root is traditionally used for the treatment of malaria in south Ethiopia. The main purpose of this study was to investigate phytochemicals and antioxidant activity of the leaf extract of Withania somnifera. The anti-oxidant potential and total antioxidant potential was determined by using reducing power determination method and phosphomolb date method respectively. As per the phytochemical tests, the methanol extract revealed that presence of tannins, phenolics, flavonoids, saponins and, alkaloids while all are absent in hexane extr
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Lingfa, Lali, Aravinda Tirumala, and Srinivas Ankanagari. "In Vitro Cytotoxicity of Reproductive Stage Withania somnifera Leaf and Stem on HepG2 Cell Line." Evidence-Based Complementary and Alternative Medicine 2023 (December 26, 2023): 1–10. http://dx.doi.org/10.1155/2023/8832166.

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Background. The ayurvedic plant Withania somnifera, a member of the Solanaceae family, has been used as a remedy for diverse health problems, including cancer. Objectives. The objective of this investigation was to conduct a comparative analysis of the in vitro cytotoxic properties of methanolic extracts derived from the leaf, stem, and root of W. somnifera on HepG2 and L929 cell lines. Methods. Methanolic extracts were obtained using the Soxhlet extraction method. To assess the in vitro anticancer action on the HepG2 and L929 cell lines, an MTT assay was performed. Changes in cell morphology
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Javaid, Arshad, and Roma Akhtar. "ANTIFUNGAL ACTIVITY OF METHANOLIC ROOT EXTRACT OF WITHANIA SOMMNIFERA AGAINST FUSARIUM OXYSPORUM F. SP. CEPAE." African Journal of Traditional, Complementary and Alternative Medicines 12, no. 5 (2015): 22–27. http://dx.doi.org/10.21010/ajtcam.v12i5.4.

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Background: Basal rot of onion (Allium cepa L.) caused by Fusarium oxysporum f. sp. cepae is a common soil-borne disease that causes significant yield losses. Generally, synthetic fungicides are used to combat the menace which cause environmental pollution. The present study was carried out to assess the antifungal activity of Withania somnifera (L.) Dunal, a Solanaceous medicinal plant, against the pathogen of this disease. 
 Materials and Methods: Different concentrations (from 0.5 to 4%) of methanolic extract of root, stem and fruit of the test plant species were prepared and their bio
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Dissertations / Theses on the topic "Somnifera Root Extract"

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MACCIONI, RICCARDO. "Phytomedicinal approach toward the treatment of CNS disorders: behavioural and biochemical evaluation of the effects of a methanolic dry root extract of Withania somnifera and its isolated metabolite, Docosanyl Ferulate, in rodent models of anxiety and drug addiction." Doctoral thesis, Università degli Studi di Cagliari, 2022. http://hdl.handle.net/11584/332548.

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The use of phytomedicinal remedies has increased during the last decades thanks to the relative low cost, low toxicity, and potential synergic effects of plant-derived medications. Withania somnifera (WS), commonly known as Indian Ginseng, is a medical plant belonging to the Indian Traditional Medical System, the Ayurveda. In preclinical studies, WS has shown an impressive variety of therapeutic effects in several pathological conditions. Among these effects, the anxiolytic and antiaddictive properties of this plant are the ones discussed in this work of thesis. Both effects have been attribu
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Book chapters on the topic "Somnifera Root Extract"

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Madhu, Nithar Ranjan, Bhanumati Sarkar, Nikhil Chandra Halder, and Biplab Kumar Behera. "Potential Applications of Traditional Medicinal Plants for Treating Sleep Disorders." In The Basic Handbook of Indian Ethnobotany and Traditional Medicine, 2nd ed. International Academic Publishing House (IAPH), 2023. http://dx.doi.org/10.52756/bhietm.2023.e02.015.

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Sleep disorders involve conditions such as insomnia, sleep apnoea and restless leg syndrome and they are realised in almost everyone ranging from children to the elderly globally. To this time, folk medicinal practices in India including West Bengal are rich in terms of Ayurveda, Unani and folk medicine: a number of herbs from these practices have been used to cure sleep disorders. Hence, vegetation and herbal medicine like Valerian (Valeriana officinalis), Chamomile (Matricaria chamomilla), Passionflower (Passiflora incarnata), Ashwagandha (Withania somnifera), Lemon Balm (Melissa officinalis
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Conference papers on the topic "Somnifera Root Extract"

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"The Protective Effect of Withania somnifera Root Extract Against Acetaminophen Induced Liver Toxicity in Cyprinus carpio Compared to Silymaryn." In International Conference on Chemical, Environment & Biological Sciences. International Institute of Chemical, Biological & Environmental Engineering, 2014. http://dx.doi.org/10.15242/iicbe.c914122.

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Sinha, Pratima, and Suzanne Ostrand-Rosenberg. "Abstract 4718: Withaferin A, a potent and abundant component of Withania somnifera root extract, reduces myeloid-derived suppressor cell function." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-4718.

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Khazal, kamel F., Donald Hill, and Clinton J. Grubbs. "Abstract 246: Mammary cancer preventive activity of an extract of withania somnifera roots." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-246.

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Elzefzafy, Nahla A., Amira Zaky, Wafaa A. Ahmed, and Ahmad Bassiouny. "Abstract 4298: Comparative inhibitory effect of different Egyptian Withania somnifera root extracts on PTEN/PI3K/AKT signaling pathway in HepG2 cell line." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-4298.

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Elzefzafy, Nahla A., Amira Zaky, Wafaa A. Ahmed, and Ahmad Bassiouny. "Abstract 4298: Comparative inhibitory effect of different Egyptian Withania somnifera root extracts on PTEN/PI3K/AKT signaling pathway in HepG2 cell line." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-4298.

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Reports on the topic "Somnifera Root Extract"

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Singh, Vineet, and Deepak Mundkinajeddu. Adulteration of Ashwagandha (Withania somnifera) Roots and Extracts. ABC-AHP-NCNPR Botanical Adulterants Prevention Program, 2019. https://doi.org/10.59520/bapp.bapb/gsha8763.

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The goal of this bulletin is to provide information and/or updates on the issue of adulteration of ashwagandha (Withania somnifera, Solanaceae) root materials and their extracts to the international herbal products industry and extended natural products community in general. It is intended to complement the previously published work on W. somnifera root and extract adulteration, i.e., the American Herbal Pharmacopoeia monograph by Upton et al.1 and the article by Mundkinajeddu et al.2 by reporting new data on the occurrence of adulteration, the market situation, and its subsequent consequences
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Journal articles
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