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Journal articles on the topic 'Southern states, discovery and exploration'

Author: Grafiati

Published: 4 June 2021

Last updated: 27 July 2025

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1

Tammiksaar, E. "The Russian Antarctic Expedition under the command of Fabian Gottlieb von Bellingshausen and its reception in Russia and the world." Polar Record 52, no. 5 (2016): 578–600. http://dx.doi.org/10.1017/s0032247416000449.

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ABSTRACTThe existence of an icy continent around the South Pole is known to everybody today. But it is common to ascribe this kind of modern knowledge to navigators sailing in southern polar waters in the 19th century. A good illustration of this is the Russian Antarctic expedition (1819–1821) under the conduct of Fabian Gottlieb von Bellingshausen (Russian version Faddej Faddeevich Bellinsgauzen), the reception of which in Russian society of the 19th and 20th centuries is analysed in this article. During the cold war, beginning at the end of the 1940s, the question of who discovered Antarctic

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Fogg, G. E. "A century of Antarctic science; planning and serendipity." Archives of Natural History 32, no. 2 (2005): 129–43. http://dx.doi.org/10.3366/anh.2005.32.2.129.

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The British National Antarctic Expedition planned with discreditable bickering, sailed for the Antarctic in 1901 on the Discovery. The venture was well equipped and commanded by R. F. Scott who, without scientific training himself, was nevertheless remarkably in empathy with his scientists. The expedition was foremost among those dispatched around the same time in establishing basic knowledge of the continent. Followed by the second Scott expedition and those of Shackleton and Mawson, a cadre of able and enthusiastic scientists was established. The second involvement of the Discovery in Antarc

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3

Hines, Elizabeth, and Michael Smith. "Gold is Where You Find It: Placer Mining in North Carolina, 1799-1849." Earth Sciences History 21, no. 2 (2002): 119–49. http://dx.doi.org/10.17704/eshi.21.2.65765421785w7460.

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The accidental discovery of a seventeen-pound gold nugget by a trio of adolescents in Cabarrus County, North Carolina in 1799 spurred a fitful gold rush that spread throughout the southeastern United States. From the early 1800s to 1849 the search for the precious metal fomented exploration and various industries along the gold-bearing regions of the Piedmont and eastern Appalachian Mountains from Alabama to Maryland. The focus of the nascent gold industry was off-season, haphazard placer mining by individuals and small family groups who used primitive medieval mining techniques and backbreaki

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Abetov, A. E., and Sh B. Yessirkepova. "Artificial intelligence in regional forecasting of oil and gas potential in the Southern Ustyurt region based on integrated geological and geophysical data." Neft i Gaz, no. 2 (April 30, 2025): 17–37. https://doi.org/10.37878/2708-0080/2025-2.02.

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The article considers the technologies of regional prediction of oil and gas content using digital technologies, artificial intelligence and innovative methods of field exploration, processing, interpretation and modeling based on the example of the South Ustyurt region (SUR). The study utilizes data from airborne gamma-ray spectrometry survey (AGRSS), gravity and magnetometry, geothermal studies, structural models for three horizons, and machine learning methods. The application of neural networks, machine learning, inversion, and spatial analysis of geological and geophysical data has improv

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Vargas, J. V. C. "EDITORIAL." Revista de Engenharia Térmica 7, no. 1 (2008): 02. http://dx.doi.org/10.5380/reterm.v7i1.61746.

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Petroleum will continue to play a key role in the world energetic matrix for long, in spite of the pessimistic predictions about the near shortage of the existing reserves. The offshore exploration technology in deep sea water has challenged such predictions. The recent discovery of oil in the pre-salt layer in the southern Brazilian sea coast is one of those events. The so called pre-salt layer consists of a region that develops along 800 kilometers between the Brazilian states of Espírito Santo and Santa Catarina, below the bottom of the sea, and encompasses three sedimentary basins (Espírit

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Flores-Argüelles, Alejandra, Rodrigo Alejandro Hernández-Cárdenas, Santiago Rosales-Martínez, Adolfo Espejo-Serna, Ana Rosa López-Ferrari, and Andrew Siekkinen. "Two new species of Hechtia (Bromeliaceae; Hechtioideae) from Jalisco, Mexico." Plant Ecology and Evolution 157, no. 1 (2024): 20–31. http://dx.doi.org/10.5091/plecevo.108472.

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Backgrounds and aims – The genus Hechtia (sensu lato) is distributed from the southern United States to northern Central America and includes 95 species. Recent botanical explorations, carried out in the Colima and Jalisco states in search of H. reticulata, led to the discovery of two new species. The aims of this work were to complete the morphological description of H. reticulata and describe these two new species. Material and methods – This study was based on fieldwork and on the revision of literature, protologues, type material, and herbarium specimens. The specimens collected were prepa

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Flores-Argüelles, Alejandra, Rodrigo Alejandro Hernández-Cárdenas, Santiago Rosales-Martínez, Adolfo Espejo-Serna, Ana Rosa López-Ferrari, and Andrew Siekkinen. "Two new species of Hechtia (Bromeliaceae; Hechtioideae) from Jalisco, Mexico." Plant Ecology and Evolution 157, no. (1) (2024): 20–31. https://doi.org/10.5091/plecevo.108472.

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Backgrounds and aims – The genus <i>Hechtia</i> (sensu lato) is distributed from the southern United States to northern Central America and includes 95 species. Recent botanical explorations, carried out in the Colima and Jalisco states in search of <i>H. reticulata</i>, led to the discovery of two new species. The aims of this work were to complete the morphological description of <i>H. reticulata</i> and describe these two new species. Material and methods – This study was based on fieldwork and on the revision of literature, protologues, type material, and herbarium specimens. The specimens

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Queiroz, Lila Costa, Adalene Moreira Silva, Frederico Ricardo Ferreira Rodrigues de Oliveira e Sousa, Michele Zorzetti Pitarello, and Márcia Abrahão Moura. "Strategies for Targeting in Undercover Terrains: Modeling Multi-Source Data in Apuí Region, SW Amazon Craton, Brazil." Minerals 13, no. 1 (2023): 78. http://dx.doi.org/10.3390/min13010078.

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Exploring covered terrains is a challenge that requires the integration of multiple sources of knowledge, particularly in the initial stages of mineral exploration. The Apuí region, located in the Southwestern Amazon Craton, has a small and constant gold production, despite the deep cover and limited geological knowledge. The gold is mainly hosted in quartz veins and breccias that cut Paleoproterozoic volcano-sedimentary sequences. The occurrences have similar characteristics to magmatic–hydrothermal deposits, such as a lack of regional metamorphism and intense hydrothermalization. We undertoo

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Garg, Sonali, Robin Suyesh, Sandeep Sukesan, and SD Biju. "Seven new species of Night Frogs (Anura, Nyctibatrachidae) from the Western Ghats Biodiversity Hotspot of India, with remarkably high diversity of diminutive forms." PeerJ 5 (February 21, 2017): e3007. http://dx.doi.org/10.7717/peerj.3007.

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The Night Frog genusNyctibatrachus(Family Nyctibatrachidae) represents an endemic anuran lineage of the Western Ghats Biodiversity Hotspot, India. Until now, it included 28 recognised species, of which more than half were described recently over the last five years. Our amphibian explorations have further revealed the presence of undescribed species of Nights Frogs in the southern Western Ghats. Based on integrated molecular, morphological and bioacoustic evidence, seven new species are formally described here asNyctibatrachus athirappillyensissp. nov.,Nyctibatrachus manalarisp. nov.,Nyctibatr

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JPT staff, _. "E&P Notes (March 2022)." Journal of Petroleum Technology 74, no. 03 (2022): 20–27. http://dx.doi.org/10.2118/0322-0020-jpt.

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Shell’s Namibia Wildcat Encounters Light Oil Supermajor Shell has struck light oil with its Graff-1 exploration well offshore Namibia, according to the country’s national oil company, a partner in the probe. The National Petroleum Corporation of Namibia (Namcor) confirmed the discovery. Partners in the Orange Basin well included Shell Namibia Upstream and QatarEnergy. The probe was located about 270 km away from Oranjemund, and was drilled to a total depth of 5376 m in water depths of 2000 m. The drilling operations on Graff-1 utilizing the Valaris DS-10 drillship began in early December 2021

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Williamson, P. E., N. F. Exon, B. ul Haq, and U. von Rad. "A NORTH WEST SHELF TRIASSIC REEF PLAY: RESULTS FROM ODP LEG 122." APPEA Journal 29, no. 1 (1989): 328. http://dx.doi.org/10.1071/aj88028.

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Site 764 of the Ocean Drilling Program (ODP), drilled during Leg 122 in the Exmouth Plateau region, cored 200 m of Upper Triassic (Rhaetian) reef complex. This site, on the northern Wombat Plateau (northernmost Exmouth Plateau) represents the first discovery of Triassic reefal material near the Australian North West Shelf. Seismic reflection data through Site 764 show that the reef itself corresponds predominantly to a seismically poorly reflective zone. A number of regional unconformities appear to correspond, however, to traceable seismic horizons which pass with reduced amplitude through th

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JPT staff, _. "E&P Notes (October 2022)." Journal of Petroleum Technology 74, no. 10 (2022): 16–20. http://dx.doi.org/10.2118/1022-0016-jpt.

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CNOOC Turns Taps on Bohai Bay Fields Volumes are flowing from two new CNOOC-operated field developments in the Bohai Sea, offshore China. Production began at the Luda 5-2 oil field north phase 1 project in Liaodong Bay. The field is in an average water depth of around 32 m. CNOOC installed one thermal recovery wellhead platform and one production platform, and connected processing facilities serving the Suizhong 36-1 oil field. The company plans to drill a total of 26 production and two water-source wells, with peak crude oil production of 8,200 B/D targeted for 2024. Oil also is flowing at th

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JPT staff, _. "E&P Notes (April 2022)." Journal of Petroleum Technology 74, no. 04 (2022): 19–25. http://dx.doi.org/10.2118/0422-0019-jpt.

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Eni Starts Area 1 Production off Mexico via MODEC FPSO MODEC said first oil has flowed through FPSO MIAMTE MV34 operating in the Offshore Area 1 block in the Bay of Campeche off Mexico. The contractor was appointed by Eni Mexico for the supply, charter, and operation of the FPSO in the Eni-operated Offshore Area 1 block in 2018. The charter contract will run for an initial 15 years, with options for extension every year thereafter up to 5 additional years. Moored in a water depth of approximately 32 m some 10 km off Mexico’s coast, the FPSO is capable of handling 90,000 B/D of oil, 75 MMcf/D o

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Kurlaev, Evgenii A. "Silver ore exploration in the Southern Urals." Izvestiya vysshikh uchebnykh zavedenii Gornyi zhurnal, no. 7 (November 11, 2020): 110–19. http://dx.doi.org/10.21440/0536-1028-2020-7-110-119.

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Introduction. Native historiography associates the beginning of Southern Ural industrialization with the construction of first metallurgical works in the 1740s. Historians paid attention to geological exploration in the Urals in the 17th century but they had no idea about the survey areas. Historical archeological study on the edge of the town of Zlatoust in the Southern Urals has managed to find the trace of the largest geological survey expedition aimed at silver ore exploration as far back as 1669–1673. Expedition at that time represented a major military autonomous formation (regiment) und

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JPT staff, _. "E&P Notes (December 2021)." Journal of Petroleum Technology 73, no. 12 (2021): 14–16. http://dx.doi.org/10.2118/1221-0014-jpt.

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Sinopec Signals Fresh Shale Success With Dongye Deep 2 Sinopec has announced that the Dongye Deep 2 key shale gas well in Dongxi, Chongqing, was drilled to a total depth of 4300 m and tested at 412000 m3/d of high-quality natural gas. The operator said the result shows significant progress in ultradeep shale gas exploration in China and will increase Sinopec’s shale gas production capacity in southeast Sichuan by more than 2 trillion m3. Following the breakthrough of the Fuling shale gas field in 2012, Sinopec has been expanding its expertise in deep shale gas. In 2018, Sinopec discovered and

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JPT staff, _. "E&P Notes (November 2021)." Journal of Petroleum Technology 73, no. 11 (2021): 14–16. http://dx.doi.org/10.2118/1121-0014-jpt.

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TotalEnergies Drills Dry Hole Offshore Suriname TotalEnergies has plugged and abandoned its Keskesi South-1 on Block 58 offshore Suriname after encountering noncommercial quantities of hydrocarbons. Keskesi South-1 was drilled about 6.2 km from the discovery well Keskesi East-1. “The first appraisal well at Keskesi was a substantial stepout designed to assess the southern extent of the feature,” said Tracey K. Henderson, senior vice president, exploration at APA, a partner in the block. “This location had the potential to confirm a very large resource in place if connected to the reservoir san

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Limbert, H., D. Limbert, N. Hieu, et al. "The discovery and exploration of Hang Son Doong." Boletín Geológico y Minero 127, no. 1 (2016): 165–76. http://dx.doi.org/10.21701/bolgeomin.127.1.011.

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Hang Son Doong is located in the Phong Nha Ke Bang Limestone Massif in Quang Binh Province, Central Vietnam. Cave exploration by British cavers has been continuous in this area since 1990. Hang Son Doong is part of the Phong Nha Cave system which runs from the southern end of the National Park near the Lao border to the final resurgence at Phong Nha Cave.

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18

Mackie, S. I. "2001 EXPLORATION REVIEW." APPEA Journal 42, no. 2 (2002): 71. http://dx.doi.org/10.1071/aj01059.

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Exploration expenditure in 2001 was the highest ever and successful wildcats were drilled in all major petroleum basins. Much of the success can be attributed to the increasing use of 3D seismic data prior to drilling. Although 2001 saw the first onshore exploration permits awarded since the mid-90s the resolution of Native Title still remains the highest concern for onshore exploration. Decreasing 2D acquisition may indicate failure to be exploring in frontier areas. The discovery of the Thylacine and Geographe fields in the offshore Otway recharged exploration on Australia’s southern margins

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Knudsen, Keld, Lisa Schofield, Tony Knight, et al. "Australian Government's exploration initiatives." APPEA Journal 59, no. 2 (2019): 899. http://dx.doi.org/10.1071/aj19007.

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Exploration is vital for the continued discovery and development of the nation’s petroleum resources – resources that are essential for energy security, economic growth, long-term regional development and jobs, improved infrastructure, and value-adding to our manufacturing industries. Governmental authorities across Australia recognise the importance of a strong exploration sector, and the Commonwealth, states and territories have several initiatives to encourage exploration.

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Schwebel, D. "EXPLORATION REVIEW." APPEA Journal 43, no. 2 (2003): 93. http://dx.doi.org/10.1071/aj02066.

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Both exploration expenditure and drilling were significantly down in 2002 in comparison to 2001. This quiet phase is primarily due to the evaluation of the 2001 drilling and seismic results which should lead, in the long term, to the next cycle of prospect drilling and re-evaluation.The amount of onshore 2D seismic acquisition data gathered was similar to 2001 with most data acquired primarily in the producing basins.Offshore seismic acquisition was down markedly due the completion of a number of major 3D surveys. These data are now in the processing and interpretation phase and when completed

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Forsyth, Carol M., Arthur C. Graesser, Philip Jr Pavlik, et al. "Operation ARIES!: Methods, Mystery, and Mixed Models: Discourse Features Predict Affect in a Serious Game." Journal of Educational Data Mining 5, no. 1 (2013): 147–89. https://doi.org/10.5281/zenodo.3554616.

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Operation ARIES! is an Intelligent Tutoring System that is designed to teach scientific methodology in a game-like atmosphere. A fundamental goal of this serious game is to engage students during learning through natural language tutorial conversations. A tight integration of cognition, discourse, motivation, and affect is desired to meet this goal. Forty-six undergraduate students from two separate colleges in Southern California interacted with Operation ARIES! while intermittently answering survey questions that tap specific affective and metacognitive states related to the game-like and in

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Saunders, Jim, Mark Steltenpohl, and Robert B. Cook. "Gold Exploration and Potential of the Appalachian Piedmont of Eastern Alabama." SEG Discovery, no. 94 (July 1, 2013): 1–17. http://dx.doi.org/10.5382/segnews.2013-94.fea.

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ABSTRACT: The discovery and production of gold from epithermal and volcanogenic massive sulfide deposits in the Carolina slate belt of the southern Appalachians perhaps have overshadowed the gold potential of orogenic gold deposits in relatively higher grade metamorphic terranes of the southern Appalachian Piedmont. There has been a limited amount of exploration in the non-Carolina slate belt southern Appalachians since the early 1980s. Here we describe some of the recent exploration activity and geology of gold occurrences in the most productive part of the Alabama Piedmont, including the Gol

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GENDALL, IAN R., LUIS A. QUEVEDO, RICHARD H. SILLITOE, et al. "Discovery of a Jurassic Porphyry Copper Belt, Pangui Area, Southern Ecuador." SEG Discovery, no. 43 (October 1, 2000): 1–15. http://dx.doi.org/10.5382/segnews.2000-43.fea.

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ABSTRACT Grassroots exploration has led to discovery of 10 porphyry copper prospects in the previously unexplored Jurassic arc of southeastern Ecuador. The prospects are located in steep, wet, jungle-covered terrain in the Pangui area, part of the Cordillera del Cóndor. The exploration program, initially mounted in search of gold in the Oriente foreland basin, employed panned-concentrate drainage sampling. Follow-up of the resulting anomalies utilized soil sampling combined with rock-chip sampling and geologic mapping of the restricted creek outcrops. Scout and infill drilling of two of the pr

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JPT staff, _. "E&P Notes (June 2022)." Journal of Petroleum Technology 74, no. 06 (2022): 14–19. http://dx.doi.org/10.2118/0622-0014-jpt.

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Sonadrill Lands Contract for Drillship Seadrill confirmed a new contract has been secured by Sonadrill Holding, Seadrill’s 50:50 joint venture with an affiliate of Sonangol for the drillship West Gemini. Sonadrill has secured a 10‑well contract with options for up to eight additional wells in Angola for an unknown operator. Total contract value for the firm portion of the deal is expected to be around $161 million, with further revenue potential from a performance bonus. The rig is expected to begin the work in the fourth quarter of this year with a firm term of about 18 months, in direct cont

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Weng, Suzie S., and Shinwoo Choi. "Asian Americans’ Ethnic Identity Exploration and the Role of Ethnic Community in a Southern City in the United States." Societies 11, no. 3 (2021): 109. http://dx.doi.org/10.3390/soc11030109.

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This qualitative study explores Asian Americans’ ethnic identity concerning their process of exploring their own identity belonging and the impact of an ethnic community in a southern city in the United States. The South has mainly consisted of European Americans and African Americans. However, it has diversified to include an increasing number of Latinx and Asian Americans over the last several decades. Yet, the growing Asian American community remains disparate in its ethnic identity and nationality. Therefore, this study uses the phenomenological method to provide a more in-depth understand

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Chłodnicki, Marek, and Krzysztof M. Ciałowicz. "Tell el-Farkha: archaeological fieldwork 2018–2019." Polish Archaeology in the Mediterranean, no. 29/2 (December 31, 2020): 61–86. http://dx.doi.org/10.31338/uw.2083-537x.pam29.2.02.

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The Tell el-Farkha site, which has been excavated since 1998, is formed of three tells. All three were excavated in the course of the two seasons, reopening already established trenches. Breweries discovered earlier on the Western Kom were explored, two completely, two in the early stages of exploration. Thick poorly preserved mud-brick walls were unearthed northeast of one of the breweries. Remains of a multi-roomed structure continued to be cleared in the northern trench on the Central Kom. D-shaped red bricks in this area suggest the presence of a brewery in the vicinity. A Naqada IIB and I

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Baxter, M. F. W., Zulkiflie Abdullah, and M. R. Pearson. "Operational Procedures and Applications of a Wireline Formation Tester To Accurately Characterize the Gas Composition of Stacked Multiple Pools in the North Malay Basin." SPE Reservoir Evaluation & Engineering 3, no. 02 (2000): 101–8. http://dx.doi.org/10.2118/62482-pa.

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Summary In this article we review the development of techniques to acquire reliable reservoir gas samples using a wireline formation tester in the Malaysia-Thailand Joint Development Area. This region is characterized by gas accumulations comprised of multiple stacked separate pools where reservoir conditions are often considered hostile for wireline logging operations. In the article we use data from the 16-well exploration and appraisal program, during which 1968 pre-tests and 124 samples were successfully acquired, to compare the quality of gas samples from a wireline formation tester with

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Cavender, A. "Folk medical uses of plant foods in southern Appalachia, United States." Journal of Ethnopharmacology 108, no. 1 (2006): 74–84. http://dx.doi.org/10.1016/j.jep.2006.04.008.

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Lavering, L. H., V. L. Passmore, and I. M. Paton. "DISCOVERY AND EXPLOITATION OF NEW OILFIELDS IN THE COOPER-EROMANGA BASINS." APPEA Journal 26, no. 1 (1986): 250. http://dx.doi.org/10.1071/aj85024.

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Since 1975 the level of petroleum exploration in the Cooper-Eromanga basins has undergone an unprecedented expansion due to the discovery and development of an increasing number of oil reservoirs, largely in the Eromanga Basin sequence. The commercial incentive provided by the Commonwealth Government's Import Parity Pricing and excise arrangements have been instrumental in the lead up to and continuation of this series of discoveries.Three types of oil discovery in the Eromanga Basin sequence are evident; firstly, shallow pools above Cooper Basin gas fields; secondly, separate single-field dis

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Weng, Suzie S., and Warren T. Wolfe. "An Asian American community in the Southern United States: An exploration of fear of crime." Journal of Ethnicity in Criminal Justice 14, no. 3 (2016): 157–71. http://dx.doi.org/10.1080/15377938.2015.1065779.

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HAIRR, JOHN. "THE EXPLORATION AND FIRST ASCENT OF MOUNT WHITNEY, CALIFORNIA." Earth Sciences History 38, no. 1 (2019): 28–42. http://dx.doi.org/10.17704/1944-6178-38.1.28.

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ABSTRACT Mount Whitney, California, rises 14,505 feet in the Sierra Nevada of California. At the time of its discovery by members of the California Geological Survey in 1864, Mount Whitney was the highest peak in what then comprised the United States and remains the highest peak in the country south of Alaska. This paper examines early attempts to explore the mountain, measure its altitude and accurately plot its location

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Köberer, Wolfgang. "Navigating by the Southern Cross: A history of the European discovery and exploration of Australia." Mariner's Mirror 108, no. 2 (2022): 242–45. http://dx.doi.org/10.1080/00253359.2022.2055843.

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Köberer, Wolfgang. "Navigating by the Southern Cross: A history of the European discovery and exploration of Australia." Mariner's Mirror 108, no. 2 (2022): 242–45. http://dx.doi.org/10.1080/00253359.2022.2055843.

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Dave, Vedant, and Elmar Rueckert. "Skill Disentanglement in Reproducing Kernel Hilbert Space." Proceedings of the AAAI Conference on Artificial Intelligence 39, no. 15 (2025): 16153–62. https://doi.org/10.1609/aaai.v39i15.33774.

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Unsupervised Skill Discovery aims at learning diverse skills without any extrinsic rewards and leverage them as prior for learning a variety of downstream tasks. Existing approaches to unsupervised reinforcement learning typically involve discovering skills through empowerment-driven techniques or by maximizing entropy to encourage exploration. However, this mutual information objective often results in either static skills that discourage exploration or maximise coverage at the expense of non-discriminable skills. Instead of focusing only on maximizing bounds on f-divergence, we combine it wi

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Chen, Xuan, Joe A. MacGown, Benjamin J. Adams, Katherine A. Parys, Rachel M. Strecker, and Linda Hooper-Bui. "First Record ofPyramica epinotalis(Hymenoptera: Formicidae) for the United States." Psyche: A Journal of Entomology 2012 (2012): 1–7. http://dx.doi.org/10.1155/2012/850893.

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Pyramica epinotalisis an arboreal dacetine ant previously known only from Brazil, Costa Rica, Ecuador, and southern Mexico. Here we report the first records ofP. epinotalisfor the United States. Collections were made in three parishes across southern Louisiana in cypress-tupelo swamps using floating pitfall traps placed in floating vegetation and arboreal pitfall traps placed on trunks and limbs of three wetland tree species. One additional specimen of this species was collected in Highlands County, Florida. Based on collections of specimens in Louisiana, including multiple dealate females at

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Samuel, Madeline, Hyunsuk Choi, Haesang Kang, and Myong Jae Lee. "Sustainable Event Planning: An Exploration of University Conference Centers." Sustainability 13, no. 13 (2021): 7194. http://dx.doi.org/10.3390/su13137194.

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The use of conference services on university campuses has grown in recent years. Focusing on three university conference centers in Southern California in the United States, this study explores innovative practices, tools, and strategies that sales and marketing teams can use to attract potential clients to campus facilities. A Delphi method with a panel of eight sales and marketing experts from three university conference centers was used to examine tools and strategies used by university conference centers. The findings reveal that email marketing, tradeshows, and social media are effective

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Đoković, Nemanja, Dušan Ružić, Minna Rahnasto-Rilla, Tatjana Srdic-Rajic, Maija Lahtela-Kakkonen, and Katarina Nikolić. "Expanding the Accessible Chemical Space of SIRT2 Inhibitors through Exploration of Binding Pocket Dynamics." J Chem Inf Model 62, no. 10 (2022): 2571–85. https://doi.org/10.1021/acs.jcim.2c00241.

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Abstract Considerations of binding pocket dynamics are one of the crucial aspects of the rational design of binders. Identification of alternative conformational states or cryptic subpockets could lead to the discovery of completely novel groups of the ligands. However, experimental characterization of pocket dynamics, besides being expensive, may not be able to elucidate all of the conformational states relevant for drug discovery projects. In this study, we propose the protocol for computational simulations of sirtuin 2 (SIRT2) binding pocket dynamics and its integration into the structure-b

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Abbink, O. A., H. F. Mijnlieff, D. K. Munsterman, and R. M. C. H. Verreussel. "New stratigraphic insights in the ’Late Jurassic’ of the Southern Central North Sea Graben and Terschelling Basin (Dutch Offshore) and related exploration potential." Netherlands Journal of Geosciences - Geologie en Mijnbouw 85, no. 3 (2006): 221–38. http://dx.doi.org/10.1017/s001677460002148x.

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AbstractMiddle Jurassic - Early Cretaceous strata are a target for oil and gas exploration in the Dutch offshore. During the initial stages of the ‘Late Jurassic’ offshore exploration, various oil fields and a few gas fields were discovered of which only one, the F3-FB field, proved to be economically viable. In the Northern Offshore of the Netherlands, latest Middle Jurassic (Callovian) - earliest Cretaceous (Ryazanian) strata are mostly limited to the Dutch Central Graben and Terschelling basins. Outside the Dutch Central Graben and the Terschelling Basin only thin veneers of these strata oc

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Hassemer, Gustavo, João Paulo Ramos Ferreira, Luís Adriano Funez, and Rafael Trevisan. "First records of Melilotus albus Medik. (Fabaceae, Faboideae) in Santa Catarina, southern Brazil." Check List 11, no. 1 (2015): 1499. http://dx.doi.org/10.15560/11.1.1499.

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Melilotus albus Medik. is a cosmopolite and invasive species, native to the Old World, which in Brazil had its occurrence hitherto recorded only in the states of São Paulo, Paraná and Rio Grande do Sul. This study extends its distribution to Santa Catarina state, southern Brazil, due to the recent discovery of populations in the municipalities of Florianópolis and Xanxerê. These new records are ca. 250 km distant from the nearest records, in Paraná state, also in southern Brazil.

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Nguyen, Phuc, Sylvia Chien, Jin Dai, Raymond J. Monnat, Pamela S. Becker, and Hao Yuan Kueh. "Unsupervised discovery of dynamic cell phenotypic states from transmitted light movies." PLOS Computational Biology 17, no. 12 (2021): e1009626. http://dx.doi.org/10.1371/journal.pcbi.1009626.

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Identification of cell phenotypic states within heterogeneous populations, along with elucidation of their switching dynamics, is a central challenge in modern biology. Conventional single-cell analysis methods typically provide only indirect, static phenotypic readouts. Transmitted light images, on the other hand, provide direct morphological readouts and can be acquired over time to provide a rich data source for dynamic cell phenotypic state identification. Here, we describe an end-to-end deep learning platform, UPSIDE (Unsupervised Phenotypic State IDEntification), for discovering cell sta

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Budhwani, Henna, B. Matthew Kiszla, Angulique Y. Outlaw, et al. "Adapting a Motivational Interviewing Intervention to Improve HIV Prevention Among Young, Black, Sexual Minority Men in Alabama: Protocol for the Development of the Kings Digital Health Intervention." JMIR Research Protocols 11, no. 7 (2022): e36655. http://dx.doi.org/10.2196/36655.

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Background African American or Black young men who have sex with men (BYMSM) are at a disproportionate risk for contracting HIV and have high rates of undiagnosed, and therefore untreated, HIV infection. In the southern United States, BYMSM face region-specific hurdles to HIV prevention, such as limited access to care and high levels of racism and intersectional stigma, necessitating HIV testing and pre-exposure prophylaxis interventions that address sociocultural and structural barriers while motivating BYMSM to engage in prevention. Brothers Saving Brothers (BSB) is a motivational interviewi

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Borgarelli, Andrea, Constantin Enea, Rupak Majumdar, and Srinidhi Nagendra. "Reward Augmentation in Reinforcement Learning for Testing Distributed Systems." Proceedings of the ACM on Programming Languages 8, OOPSLA2 (2024): 1928–54. http://dx.doi.org/10.1145/3689779.

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Bugs in popular distributed protocol implementations have been the source of many downtimes in popular internet services. We describe a randomized testing approach for distributed protocol implementations based on reinforcement learning. Since the natural reward structure is very sparse, the key to successful exploration in reinforcement learning is reward augmentation. We show two different techniques that build on one another. First, we provide a decaying exploration bonus based on the discovery of new states---the reward decays as the same state is visited multiple times. The exploration bo

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Hassemer, Gustavo, João Paulo Ferreira, Luís Funez, and Rafael Trevisan. "First records of Melilotus albus Medik. (Fabaceae, Faboideae) in Santa Catarina, southern Brazil." Check List 11, no. (1) (2015): 1–4. https://doi.org/10.15560/11.1.1499.

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<em>Melilotus albus</em> Medik. is a cosmopolite and invasive species, native to the Old World, which in Brazil had its occurrence hitherto recorded only in the states of São Paulo, Paraná and Rio Grande do Sul. This study extends its distribution to Santa Catarina state, southern Brazil, due to the recent discovery of populations in the municipalities of Florianópolis and Xanxerê. These new records are <em>ca.</em> 250 km distant from the nearest records, in Paraná state, also in southern Brazil.

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Noritaka, YAGASAKI. "Regional Geography of the United States as Exploration and Discovery: Moving toward Reconstructing Regional Geography." Geographical review of Japan series A 88, no. 2 (2015): 83–101. http://dx.doi.org/10.4157/grj.88.83.

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Wilson, R. Trevor. "The biological exploration of Darfur, 1799–1998." Archives of Natural History 39, no. 1 (2012): 39–58. http://dx.doi.org/10.3366/anh.2012.0061.

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Darfur covers an area in excess of 400,000 square kilometres in the west of the Republic of Sudan. The Sultanate of Darfur was an independent entity for eight centuries. Three “outsiders” in the sultanate commented on its biology before its annexation by Egypt in the 1870s. A naturalist accompanied the Egyptian invasion but the area was overrun by Mahdist forces in 1883, then reverted to independence in 1898 before incorporation into the Anglo-Egyptian Sudan 1916. No outsiders entered Darfur in the period 1883–1916 but information from spies and informers on wildlife and trade in products appe

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Leontiev, D. S., and A. A. Arsenyev. "On the prospects of gas potential in the Southern and Southeastern parts of the Kurgan region." Oil and Gas Studies, no. 1 (February 24, 2025): 24–37. https://doi.org/10.31660/0445-0108-2025-1-24-37.

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At present, the issue of oil and gas potential in the Kurgan region, the question remains open. Without convincing evidence, some specialists believe that the depths of the Kurgan TransUrals is of little interest for hydrocarbon extraction.On the other hand, some experts suggest that, although the hydrocarbon deposits in the region are not large, their discovery is possible if the directions for exploration and prospecting work are carefully justified, with special attention to Paleozoic deposits.The aim of the study is to examine the gas potential of the southern and southeastern parts of the

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Mannella, Carmen. "In Silico Exploration of Alternative Conformational States of VDAC." Molecules 28, no. 8 (2023): 3309. http://dx.doi.org/10.3390/molecules28083309.

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VDAC (Voltage-Dependent Anion-selective Channel) is the primary metabolite pore in the mitochondrial outer membrane (OM). Atomic structures of VDAC, consistent with its physiological “open” state, are β-barrels formed by 19 transmembrane (TM) β-strands and an N-terminal segment (NTERM) that folds inside the pore lumen. However, structures are lacking for VDAC’s partially “closed” states. To provide clues about possible VDAC conformers, we used the RoseTTAFold neural network to predict structures for human and fungal VDAC sequences modified to mimic removal from the pore wall or lumen of “crypt

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Mbona, Reginald Masimba, Chilombo Stephania Mumba, and Tinashe Mangudhla. "Fixed Investment and Economic Growth: ARDL and Causality Exploration for SADC Countries." Business and Economic Research 11, no. 4 (2021): 18. http://dx.doi.org/10.5296/ber.v11i4.18659.

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In assessing the short run and the long-run effects of fixed investment and economic growth among Southern Africa countries, we evaluated the economic progress of the SADC (Southern African Development Committee) region. Our objective is to determine how variables (GDP, purchasing power parity, inflation, electricity, balance-of-payments, and unemployment) can be affected by the fixed investment. In determining how fixed investment affects economic activities and policies among the states, the ADRL estimation approach is applied. Using data from 13 countries in the SADC region from the period

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ANGELETTI, L., M. TAVIANI, S. CANESE, et al. "New deep-water cnidarian sites in the southern Adriatic Sea." Mediterranean Marine Science 15, no. 2 (2013): 263. http://dx.doi.org/10.12681/mms.558.

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Recent ROV (Remotely Operated Vehicle) exploration and bottom sampling in the southern Adriatic Sea (Apulian and Montenegrin margins) resulted in the discovery of cnidarian-rich deep-sea habitats in the depth range of ca. 400-700 m. In particular, ROV inspection of Montenegrin canyons reveals the existence of megabenthic communities dominated by a variety of cnidarians, including scleractinians (Madrepora oculata, Lophelia pertusa, Dendrophyllia cornigera), antipatharians (Leiopathes glaberrima) and gorgonians (Callogorgia verticillata) as major habitat forming taxa, often in association with

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Budd, Grahame M. "Australian exploration of Heard Island, 1947–1971." Polar Record 43, no. 2 (2007): 97–123. http://dx.doi.org/10.1017/s0032247407006080.

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In 1947 knowledge of Heard Island was confined to a rough mapping compiled by nineteenth-century sealers, and the results of four scientific expeditions that had briefly investigated the Atlas Cove area. Exploration continued in two distinct periods between 1947 and 1971. In the first period the Australian National Antarctic Research Expeditions (ANARE) built a scientific station at Atlas Cove in 1947, and occupied it continuously until 1955 as an ‘A Class’ meteorological station, a seismic and magnetic observatory, and a base for other scientific studies and for exploration of the island. In

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