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Relevant bibliographies by topics / Spatio-temporal Regulators

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Journal articles

Academic literature on the topic 'Spatio-temporal Regulators'

Author: Grafiati

Published: 6 September 2023

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Journal articles on the topic "Spatio-temporal Regulators"

1

Fritz, Rafael Dominik, and Olivier Pertz. "The dynamics of spatio-temporal Rho GTPase signaling: formation of signaling patterns." F1000Research 5 (April 26, 2016): 749. http://dx.doi.org/10.12688/f1000research.7370.1.

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Rho GTPases are crucial signaling molecules that regulate a plethora of biological functions. Traditional biochemical, cell biological, and genetic approaches have founded the basis of Rho GTPase biology. The development of biosensors then allowed measuring Rho GTPase activity with unprecedented spatio-temporal resolution. This revealed that Rho GTPase activity fluctuates on time and length scales of tens of seconds and micrometers, respectively. In this review, we describe Rho GTPase activity patterns observed in different cell systems. We then discuss the growing body of evidence that upstre

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2

Bakhsh, A., K. Shahzad, and T. Husnain. "Variation in the spatio-temporal expression of insecticidal genes in cotton." Czech Journal of Genetics and Plant Breeding 47, No. 1 (2011): 1–9. http://dx.doi.org/10.17221/131/2010-cjgpb.

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The most significant breakthrough in plant biotechnology is the development of the techniques to transform genes from unrelated sources into commercially important crop plants to develop resistance against targeted insect pests. The spatio-temporal expression of insecticidal genes in transgenic cotton varies with plant age, plant parts and environmental conditions. The understanding of this temporal and spatial variation in efficacy and the resulting mechanisms is essential for cotton protection and production. This review summarizes variations in the efficacy of introduced insecticidal genes

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3

Hill, Robert E., and Laura A. Lettice. "Alterations to the remote control of Shh gene expression cause congenital abnormalities." Philosophical Transactions of the Royal Society B: Biological Sciences 368, no. 1620 (2013): 20120357. http://dx.doi.org/10.1098/rstb.2012.0357.

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Multi-species conserved non-coding elements occur in the vertebrate genome and are clustered in the vicinity of developmentally regulated genes. Many are known to act as cis -regulators of transcription and may reside at long distances from the genes they regulate. However, the relationship of conserved sequence to encoded regulatory information and indeed, the mechanism by which these contribute to long-range transcriptional regulation is not well understood. The ZRS, a highly conserved cis -regulator, is a paradigm for such long-range gene regulation. The ZRS acts over approximately 1 Mb to

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4

Sun, Shuo, Changyu Yi, Jing Ma, et al. "Analysis of Spatio-Temporal Transcriptome Profiles of Soybean (Glycine max) Tissues during Early Seed Development." International Journal of Molecular Sciences 21, no. 20 (2020): 7603. http://dx.doi.org/10.3390/ijms21207603.

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Soybean (Glycine max) is an important crop providing oil and protein for both human and animal consumption. Knowing which biological processes take place in specific tissues in a temporal manner will enable directed breeding or synthetic approaches to improve seed quantity and quality. We analyzed a genome-wide transcriptome dataset from embryo, endosperm, endothelium, epidermis, hilum, outer and inner integument and suspensor at the global, heart and cotyledon stages of soybean seed development. The tissue specificity of gene expression was greater than stage specificity, and only three genes

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5

Pintard, Lionel, and Vincent Archambault. "A unified view of spatio-temporal control of mitotic entry: Polo kinase as the key." Open Biology 8, no. 8 (2018): 180114. http://dx.doi.org/10.1098/rsob.180114.

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The Polo kinase is an essential regulator of cell division. Its ability to regulate multiple events at distinct subcellular locations and times during mitosis is remarkable. In the last few years, a much clearer mechanistic understanding of the functions and regulation of Polo in cell division has emerged. In this regard, the importance of coupling changes in activity with changes in localization is striking, both for Polo itself and for its upstream regulators. This review brings together several new pieces of the puzzle that are gradually revealing how Polo is regulated, in space and time, t

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6

Pang, Junling, Xia Zhang, Xuhui Ma, and Jun Zhao. "Spatio-Temporal Transcriptional Dynamics of Maize Long Non-Coding RNAs Responsive to Drought Stress." Genes 10, no. 2 (2019): 138. http://dx.doi.org/10.3390/genes10020138.

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Long non-coding RNAs (lncRNAs) have emerged as important regulators in plant stress response. Here, we report a genome-wide lncRNA transcriptional analysis in response to drought stress using an expanded series of maize samples collected from three distinct tissues spanning four developmental stages. In total, 3488 high-confidence lncRNAs were identified, among which 1535 were characterized as drought responsive. By characterizing the genomic structure and expression pattern, we found that lncRNA structures were less complex than protein-coding genes, showing shorter transcripts and fewer exon

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7

Warmerdam, Daniël O., Roland Kanaar, and Veronique A. J. Smits. "Differential Dynamics of ATR-Mediated Checkpoint Regulators." Journal of Nucleic Acids 2010 (2010): 1–16. http://dx.doi.org/10.4061/2010/319142.

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The ATR-Chk1 checkpoint pathway is activated by UV-induced DNA lesions and replication stress. Little was known about the spatio and temporal behaviour of the proteins involved, and we, therefore, examined the behaviour of the ATRIP-ATR and Rad9-Rad1-Hus1 putative DNA damage sensor complexes and the downstream effector kinase Chk1. We developed assays for the generation and validation of stable cell lines expressing GFP-fusion proteins. Photobleaching experiments in living cells expressing these fusions indicated that after UV-induced DNA damage, ATRIP associates more transiently with damaged

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8

Shan, Xiaotong, Yueqing Li, Song Yang, et al. "The spatio‐temporal biosynthesis of floral flavonols is controlled by differential phylogenetic MYB regulators in Freesia hybrida." New Phytologist 228, no. 6 (2020): 1864–79. http://dx.doi.org/10.1111/nph.16818.

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9

Botti, Gerardo, Clemente Cillo, Rossella De Cecio, Maria Gabriella Malzone, and Monica Cantile. "Paralogous HOX13 Genes in Human Cancers." Cancers 11, no. 5 (2019): 699. http://dx.doi.org/10.3390/cancers11050699.

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Hox genes (HOX in humans), an evolutionary preserved gene family, are key determinants of embryonic development and cell memory gene program. Hox genes are organized in four clusters on four chromosomal loci aligned in 13 paralogous groups based on sequence homology (Hox gene network). During development Hox genes are transcribed, according to the rule of “spatio-temporal collinearity”, with early regulators of anterior body regions located at the 3’ end of each Hox cluster and the later regulators of posterior body regions placed at the distal 5’ end. The onset of 3’ Hox gene activation is de

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10

Gao, Yuanhui, Hui Cao, Denggao Huang, Linlin Zheng, Zhenyu Nie, and Shufang Zhang. "RNA-Binding Proteins in Bladder Cancer." Cancers 15, no. 4 (2023): 1150. http://dx.doi.org/10.3390/cancers15041150.

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RNA-binding proteins (RBPs) are key regulators of transcription and translation, with highly dynamic spatio-temporal regulation. They are usually involved in the regulation of RNA splicing, polyadenylation, and mRNA stability and mediate processes such as mRNA localization and translation, thereby affecting the RNA life cycle and causing the production of abnormal protein phenotypes that lead to tumorigenesis and development. Accumulating evidence supports that RBPs play critical roles in vital life processes, such as bladder cancer initiation, progression, metastasis, and drug resistance. Unc

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