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Journal articles on the topic 'Specks'

Author: Grafiati

Published: 4 June 2021

Last updated: 4 February 2022

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1

Broderick, Lori, and Hal M. Hoffman. "cASCading specks." Nature Immunology 15, no. 8 (2014): 698–700. http://dx.doi.org/10.1038/ni.2942.

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2

Whitaker, T. B., J. W. Dickens, and A. B. Slate. "Grading Peanut Butter Using Video Image Analysis Techniques1." Peanut Science 14, no. 2 (1987): 74–79. http://dx.doi.org/10.3146/i0095-3679-14-2-6.

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Abstract A video image analysis system was designed to quantitatively measure the amount of specks and the color of peanut butter samples for grade purposes. The video image of a peanut butter surface 5.8 cm by 5.8 cm was captured and converted into 384 by 384 picture elements (pixels). The intensity of each of the 147,456 pixels was classified into one of 256 shades of gray from zero for black to 255 for white. The percent of total pixels that represented specks was defined as the speck index. The aveage shade of gray of all 147,456 pixels was defined as the color index. The speck and color i

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3

Kuri, Paola, Nicole L. Schieber, Thomas Thumberger, Joachim Wittbrodt, Yannick Schwab, and Maria Leptin. "Dynamics of in vivo ASC speck formation." Journal of Cell Biology 216, no. 9 (2017): 2891–909. http://dx.doi.org/10.1083/jcb.201703103.

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Activated danger or pathogen sensors trigger assembly of the inflammasome adaptor ASC into specks, large signaling platforms considered hallmarks of inflammasome activation. Because a lack of in vivo tools has prevented the study of endogenous ASC dynamics, we generated a live ASC reporter through CRISPR/Cas9 tagging of the endogenous gene in zebrafish. We see strong ASC expression in the skin and other epithelia that act as barriers to insult. A toxic stimulus triggered speck formation and rapid pyroptosis in keratinocytes in vivo. Macrophages engulfed and digested that speck-containing, pyro

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4

Basiorka, Ashley A., Zhenjun Ma, Kathy L. Mcgraw, et al. "NLRP3 Inflammasome-Derived ASC Specks Are a Diagnostic Biomarker for Myelodysplastic Syndromes (MDS)." Blood 128, no. 22 (2016): 2005. http://dx.doi.org/10.1182/blood.v128.22.2005.2005.

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Abstract Background: We reported that ineffective hematopoiesis in MDS results from caspase-1-dependent, pyroptotic cell death. Pyroptosis, which culminates in cytolysis, is initiated by the NOD-like receptor NLRP3, a redox-sensitive, cytosolic sensor of danger signals. Upon activation, NLRP3 recruits the ASC (apoptosis-associated speck-like protein containing a CARD (caspase activation and recruitment domain)) adapter protein that polymerizes to create large cytoplasmic filaments. Exposure of the ASCCARDdomain on the filament surface fosters docking of pro-caspase-1 that initiates processing

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5

Balci-Peynircioglu, Banu, Andrea L. Waite, Philip Schaner, et al. "Expression of ASC in Renal Tissues of Familial Mediterranean Fever Patients with Amyloidosis: Postulating a Role for ASC in AA Type Amyloid Deposition." Experimental Biology and Medicine 233, no. 11 (2008): 1324–33. http://dx.doi.org/10.3181/0803-rm-106.

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Familial Mediterranean fever (FMF) is characterized by recurrent attacks of fever and serositis; in some cases, ensuing amyloidosis results in kidney damage. Treatment with colchicine reduces the frequency and severity of FMF attacks and prevents amyloidosis, although the mechanisms behind these effects are unknown. Pyrin, the protein product of the MEFV gene, interacts with ASC, a key molecule in apoptotic and inflammatory processes. ASC forms intracellular speck-like aggregates that presage cell death. Here we show that cell death after ASC speck formation is much slower in nonmyeloid cells

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6

Lee, SangJoon, Akari Ishitsuka, Masayuki Noguchi, et al. "Influenza restriction factor MxA functions as inflammasome sensor in the respiratory epithelium." Science Immunology 4, no. 40 (2019): eaau4643. http://dx.doi.org/10.1126/sciimmunol.aau4643.

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The respiratory epithelium is exposed to the environment and initiates inflammatory responses to exclude pathogens. Influenza A virus (IAV) infection triggers inflammatory responses in the respiratory mucosa, but the mechanisms of inflammasome activation are poorly understood. We identified MxA as a functional inflammasome sensor in respiratory epithelial cells that recognizes IAV nucleoprotein and triggers the formation of ASC (apoptosis-associated speck-like protein containing a CARD) specks via interaction of its GTPase domain with the PYD domain of ASC. ASC specks were present in bronchiol

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7

Huber, Patrick, Laurent Lyannaz, and Bruno Carré. "Specks masking by the coating layer in coated paper made from deinked pulp." Nordic Pulp & Paper Research Journal 27, no. 2 (2012): 466–71. http://dx.doi.org/10.3183/npprj-2012-27-02-p466-471.

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Abstract Production of lightweight coated paper (LWC) utilises more and more deinked pulp (DIP), for both economical and environmental reasons. A critical requirement on DIP quality for such grades is the cleanliness of the pulp. Indeed, the coating layer may not fully cover specks in the base paper. The objective of this work was to determine the required specifications of the coating layer to produce LWC with DIP base paper. The specks masking phenomena by the coating layer was studied from both optical measurements on coated handsheets made from DIP, and computer simulations of specks contr

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8

Wedincamp, Jimmy, Frank E. French, Robert F. Whitcomb, and Roberta B. Henegar. "Laboratory Infection and Release of Spiroplasma (Entomoplasmatales: Spiroplasmataceae) from Horse Flies (Diptera: Tabanidae)." Journal of Entomological Science 32, no. 4 (1997): 398–402. http://dx.doi.org/10.18474/0749-8004-32.4.398.

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Many tabanid flies (Diptera: Tabanidae) are infected with spiroplasmas (Mollicutes: Spiroplasmataceae). Naturally-infected Tabanus gladiator Stone and T. sulcifrons Maquart flies were restrained and fed 10% sucrose to determine the exit points of Spiroplasma from tabanid flies. The flies were allowed to feed for 24 h, and the resulting oral and anal specks were cultured in MID broth. Spiroplasmas were isolated from 21 of 51 oral specks but not from 23 anal specks deposited on plastic. In contrast, when anal specks were deposited in a sucrose solution, 9 of 28 anal specks in sucrose yielded spi

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9

Bel-Berger, Patricia, and Terri Von Hoven. "Effects of Mechanical Cleaning on Cotton Fibers: Part III: Effects of Card Wire Condition on White Specks." Textile Research Journal 67, no. 12 (1997): 857–65. http://dx.doi.org/10.1177/004051759706701201.

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Combinations of gin and mill cleaning sequences have been studied to determine the best way to clean both smooth-leaf and hairy-leaf cottons. The two varieties were subjected to four different levels of lint cleaning at the gin, followed by nine different mill cleaning sequences, for a total of thirty-six samples. All samples were tested for fiber properties (Part II), yarn strength, and fabric strength and appearance. The yarn and fabric properties are reported in this paper. In the middle of the study, the card wire was damaged and subsequently replaced, which presented the opportunity to de

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10

MAJER, GERALD. ""NAKED SPECKS OF LIVING MATTER"." Yale Review 95, no. 1 (2007): 101–28. http://dx.doi.org/10.1111/j.1467-9736.2007.00274.x.

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11

Chung, I.-Che, Lih-Chyang Chen, Ngan-Ming Tsang, et al. "Mitochondrial Oxidative Phosphorylation Complex Regulates NLRP3 Inflammasome Activation and Predicts Patient Survival in Nasopharyngeal Carcinoma." Molecular & Cellular Proteomics 19, no. 1 (2019): 142–54. http://dx.doi.org/10.1074/mcp.ra119.001808.

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We previously reported that tumor inflammasomes play a key role in tumor control and act as favorable prognostic markers in nasopharyngeal carcinoma (NPC). Activated inflammasomes frequently form distinguishable specks and govern the cellular secretion of IL-1β. However, we know little about the biological and biochemical differences between cells with and without apoptosis-associated speck-like protein containing a caspase-recruitment domain (ASC) speck formation. In this study, we used proteomic iTRAQ analysis to analyze the proteomes of NPC cells that differ in their ASC speck formation upo

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12

Robeck, Cecil M. "Specks and Logs, Catholics and Pentecostals." Pneuma 12, no. 1 (1990): 77–83. http://dx.doi.org/10.1163/157007490x00124.

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13

Ransohoff, Richard M. "Specks of insight into Alzheimer’s disease." Nature 552, no. 7685 (2017): 342–43. http://dx.doi.org/10.1038/d41586-017-08668-6.

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14

Hoss, Florian, Juan F. Rodriguez-Alcazar, and Eicke Latz. "Assembly and regulation of ASC specks." Cellular and Molecular Life Sciences 74, no. 7 (2016): 1211–29. http://dx.doi.org/10.1007/s00018-016-2396-6.

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15

Hermann, Dirk M. "ASC-Specks: Kristallisationskeime der Alzheimer-Erkrankung." InFo Neurologie & Psychiatrie 20, no. 5 (2018): 28. http://dx.doi.org/10.1007/s15005-018-2606-x.

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16

He, Xiao-fei, Yi-xuan Zeng, Ge Li, et al. "Extracellular ASC exacerbated the recurrent ischemic stroke in an NLRP3-dependent manner." Journal of Cerebral Blood Flow & Metabolism 40, no. 5 (2019): 1048–60. http://dx.doi.org/10.1177/0271678x19856226.

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Using a photothrombotic mouse model of single stroke, we show that a single stroke onset increases the nuclear factor-κB (NF-κB), NLR family CARD domain containing protein 4 (NLRC4), and absent in melanoma 2 (AIM2) inflammasomes, as well as the mRNA levels of NLRP3. Next, using a photothrombotic mouse model of recurrent stroke, we found that recurrent strokes increased the activation of NLRP3, exacerbated the brain damage and the pro-inflammatory response in wild type (WT) mice, but not in NLRP3 knockout ( NLRP3 KO) mice. Additionally, we found that apoptosis-associated speck-like protein cont

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17

Mayer, Jörg. "Red specks on honey bees (Apis mellifera)." Lab Animal 34, no. 7 (2005): 19. http://dx.doi.org/10.1038/laban0705-19.

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18

Wolf, Dominik, and Eicke Latz. "ASC specks: a biomarker for myelodysplastic syndromes?" Lancet Haematology 5, no. 9 (2018): e379-e380. http://dx.doi.org/10.1016/s2352-3026(18)30113-3.

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19

Panoy, A., and J. Malinowski. "Concentration of Silver Atoms into Developable Specks." Journal of Photographic Science 33, no. 2 (1985): 75–77. http://dx.doi.org/10.1080/00223638.1985.11738338.

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20

Hwa Lee, Mi, Hong Ryang Jung, Cheong Hwan Lim, Mi Soon Park, Ki Jeong Kim, and Sung Hun Jeung. "Optical density analysis of standard phantom for mammography quality control." International Journal of Engineering & Technology 7, no. 3.3 (2018): 22. http://dx.doi.org/10.14419/ijet.v7i2.33.13846.

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Background/Objectives: The objective of this study was to analyze optic density of dummy lesions in breast phantom by mammography and understand whether the objectivity of visual inspections on dummy lesions upon appropriate and inappropriate decisions was correct quantitatively.Methods/Statistical analysis: Study subjects were 165 phantom images in 74 hospitals nationwide that passed the test of special medical equipment by Korean Institute for Accreditation of Medical Image from May 2016 to April 2017. Min (A), Max (B), Mean (C), and StdDev (D) were measured using color level information. Fi

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21

Franklin, Bernardo S., Eicke Latz, and Florian Ingo Schmidt. "The intra- and extracellular functions of ASC specks." Immunological Reviews 281, no. 1 (2017): 74–87. http://dx.doi.org/10.1111/imr.12611.

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22

Sahillioğlu, Ali Can, and Nesrin Özören. "Artificial Loading of ASC Specks with Cytosolic Antigens." PLOS ONE 10, no. 8 (2015): e0134912. http://dx.doi.org/10.1371/journal.pone.0134912.

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23

Zheng, Runxiao, Jing Zhang, Xiaoqing Han, et al. "Particulate matter aggravates Alzheimer's disease by activating the NLRP3 inflammasome to release ASC specks." Environmental Science: Nano 8, no. 8 (2021): 2177–90. http://dx.doi.org/10.1039/d1en00361e.

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24

Sonoike, Sanemi, and Ryuuichi Yoda. "ESR Study of Silver Specks in Silver Halide Crystals." Japanese Journal of Applied Physics 28, Part 2, No. 9 (1989): L1651—L1653. http://dx.doi.org/10.1143/jjap.28.l1651.

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25

Kuge, K., H. Shimabukuro, T. Tsutsumi, et al. "Dispersion of latent image specks on reduction-sensitized emulsions." Imaging Science Journal 48, no. 3 (2000): 107–19. http://dx.doi.org/10.1080/13682199.2000.11784351.

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26

Tillema, Erik S. "Math for Real: A Speck of Dust." Mathematics Teaching in the Middle School 15, no. 6 (2010): 368–69. http://dx.doi.org/10.5951/mtms.15.6.0368.

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27

Rinehart, Robert. "Fictional Methods in Ethnography: Believability, Specks of Glass, and Chekhov." Qualitative Inquiry 4, no. 2 (1998): 200–224. http://dx.doi.org/10.1177/107780049800400204.

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28

Spalding, Mark A., and Gregory A. Campbell. "Troubleshooting Black Specks and Color Streaks in Injection Molded Parts." Plastics Engineering 69, no. 1 (2013): 28–34. http://dx.doi.org/10.1002/j.1941-9635.2013.tb00942.x.

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29

Sonoike, Sanemi, and Ryuuichi Yoda. "ESR Study of Latent Image Specks in Silver Halide Crystals." Japanese Journal of Applied Physics 29, Part 1, No. 7 (1990): 1347–52. http://dx.doi.org/10.1143/jjap.29.1347.

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30

Thapa, Ratna, and Siriwat Wongsiri. "Giant Honeybees Use Wax Specks To Recognize Old Nest Sites." Bee World 88, no. 4 (2011): 79–81. http://dx.doi.org/10.1080/0005772x.2011.11417432.

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31

Kitchen, Marcus J. "X-Ray specks: Seeing the lungs in a new light." Proceedings of the Royal Society of Victoria 125, no. 2 (2013): 82. http://dx.doi.org/10.1071/rs13028.

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32

Green, Jack P., Shi Yu, Fátima Martín-Sánchez, et al. "Chloride regulates dynamic NLRP3-dependent ASC oligomerization and inflammasome priming." Proceedings of the National Academy of Sciences 115, no. 40 (2018): E9371—E9380. http://dx.doi.org/10.1073/pnas.1812744115.

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The NLRP3 inflammasome is an important regulator of inflammation and immunity. It is a multimolecular platform formed within cells that facilitates the activation of proinflammatory caspases to drive secretion of cytokines such as interleukin-1β (IL-1β). Knowledge of the mechanisms regulating formation of the NLRP3 inflammasome is incomplete. Here we report Cl−channel-dependent formation of dynamic ASC oligomers and inflammasome specks that remain inactive in the absence of K+efflux. Formed after Cl−efflux exclusively, ASC specks are NLRP3 dependent, reversible, and inactive, although they fur

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33

Lestringant, G. G., G. A. Aal, P. M. Frossard, and K. I. Qayed. "Reticulate acropigmentation of Kitamura: pigment specks and pits in unusual locations." British Journal of Dermatology 131, no. 1 (1994): 137–39. http://dx.doi.org/10.1111/j.1365-2133.1994.tb08475.x.

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34

Morton, O. "EARTH SYSTEM PROCESSES 2 MEETING: Specks of Evidence For Ancient Sunburn." Science 309, no. 5739 (2005): 1321a. http://dx.doi.org/10.1126/science.309.5739.1321a.

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35

Kitchen, Marcus J., Genevieve A. Buckley, Andrew F. T. Leong, et al. "X-ray specks: low dosein vivoimaging of lung structure and function." Physics in Medicine and Biology 60, no. 18 (2015): 7259–76. http://dx.doi.org/10.1088/0031-9155/60/18/7259.

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36

Venegas, Carmen, Sathish Kumar, Bernardo S. Franklin та ін. "Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer’s disease". Nature 552, № 7685 (2017): 355–61. http://dx.doi.org/10.1038/nature25158.

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37

SCHATZ, HOWARD, ROBERT N. JOHNSON, and H. RICHARD McDONALD. "DIFFERENTIAL DIAGNOSIS OF DOTS, SPOTS, FLECKS, AND SPECKS OF THE FUNDUS." Retina 12, no. 1 (1992): 67–69. http://dx.doi.org/10.1097/00006982-199212010-00013.

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38

Cho, Soo Jung, Kyoung Sook Hong, Ji Hun Jeong, et al. "DROSHA-Dependent AIM2 Inflammasome Activation Contributes to Lung Inflammation during Idiopathic Pulmonary Fibrosis." Cells 8, no. 8 (2019): 938. http://dx.doi.org/10.3390/cells8080938.

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Idiopathic pulmonary fibrosis (IPF) has been linked to chronic lung inflammation. Drosha ribonuclease III (DROSHA), a class 2 ribonuclease III enzyme, plays a key role in microRNA (miRNA) biogenesis. However, the mechanisms by which DROSHA affects the lung inflammation during idiopathic pulmonary fibrosis (IPF) remain unclear. Here, we demonstrate that DROSHA regulates the absent in melanoma 2 (AIM2) inflammasome activation during idiopathic pulmonary fibrosis (IPF). Both DROSHA and AIM2 protein expression were elevated in alveolar macrophages of patients with IPF. We also found that DROSHA an

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39

Van Gorp, Hanne, Pedro H. V. Saavedra, Nathalia M. de Vasconcelos, et al. "Familial Mediterranean fever mutations lift the obligatory requirement for microtubules in Pyrin inflammasome activation." Proceedings of the National Academy of Sciences 113, no. 50 (2016): 14384–89. http://dx.doi.org/10.1073/pnas.1613156113.

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Familial Mediterranean fever (FMF) is the most common monogenic autoinflammatory disease worldwide. It is caused by mutations in the inflammasome adaptor Pyrin, but how FMF mutations alter signaling in FMF patients is unknown. Herein, we establish Clostridium difficile and its enterotoxin A (TcdA) as Pyrin-activating agents and show that wild-type and FMF Pyrin are differentially controlled by microtubules. Diverse microtubule assembly inhibitors prevented Pyrin-mediated caspase-1 activation and secretion of IL-1β and IL-18 from mouse macrophages and human peripheral blood mononuclear cells (P

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40

Turnau, Katarzyna, and Magdalena Czerwonka. "Scanning ultrastructural ontogeny of cleistothecia in the powdery mildew Microsphaera alphitoides." Acta Mycologica 22, no. 2 (2014): 223–26. http://dx.doi.org/10.5586/am.1986.025.

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Morphogenesis of cleistothecia in <i>Microsphaera alphitoides</i> Griff. et Maubl. (<i>Erysiphales, Ascomycetes</i>) on naturally infected leaf of oak was investigated with the scanning electron microscope. All phases of the life cycle of this specks have been described. Some comparisons between methods of preparation of the material have been made.

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41

Bel, Patricia, and Bugao Xu. "Image Analysis Measurements of White Specks on U.S. Extreme Varieties of Cotton." Textile Research Journal 76, no. 7 (2006): 525–33. http://dx.doi.org/10.1177/0040517506062633.

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42

Rottman, Joshua, and Liane Young. "Specks of Dirt and Tons of Pain: Dosage Distinguishes Impurity From Harm." Psychological Science 30, no. 8 (2019): 1151–60. http://dx.doi.org/10.1177/0956797619855382.

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Levels of moral condemnation often vary with outcome severity (e.g., extreme destruction is morally worse than moderate damage), but this is not always true. We investigated whether judgments of purity transgressions are more or less sensitive to variation in dosage than judgments of harm transgressions. In three studies, adults ( N = 426) made moral evaluations of harm and purity transgressions that systematically varied in dosage (frequency or magnitude). Pairs of low-dosage and high-dosage transgressions were presented such that the same sets of modifiers (e.g., “occasionally” vs. “regularl

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43

Kuge, K., H. Kaizaki, M. Nakamura, and N. Mii. "Effect of Sulphur Sensitization on the Delayed Formation of Latent Image Specks." Journal of Photographic Science 37, no. 6 (1989): 226–30. http://dx.doi.org/10.1080/00223638.1989.11737057.

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44

Zholnerova, E. A., and A. V. Vaganov. "To the taxonomy of the family Liliaceae Juss. in Altai Mountain Country." Проблемы ботаники Южной Сибири и Монголии 19, no. 1 (2020): 33–38. http://dx.doi.org/10.14258/pbssm.2020007.

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The work presents a comparative morphological analysis of the distinctive characteristics of the LiliaceaeJuss. family representatives, growing in the Altai Mountain Country based on the materials of Herbaria ALTB and YALT,as well as digital collections NS (NSK), MW, FRU, E, CAS, B and G. Based on the analysis of literary sources, herbariumspecimens and studies of representatives in the environment the main morphological characteristics of species, genera andfamily as a whole have been identified. For representatives of the genus Streptopus Michaux. with the rhizome type ofunderground organs,

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45

Efimov, Vladimir P. "Roles of NUDE and NUDF Proteins of Aspergillus nidulans: Insights from Intracellular Localization and Overexpression Effects." Molecular Biology of the Cell 14, no. 3 (2003): 871–88. http://dx.doi.org/10.1091/mbc.e02-06-0359.

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The NUDF protein of the filamentous fungus Aspergillus nidulans functions in the cytoplasmic dynein pathway. It binds several proteins, including the NUDE protein. Green fluorescent protein-tagged NUDF and NUDA (dynein heavy chain) localize to linearly moving dashes (“comets”) that coincide with microtubule ends. Herein, deletion of the nudE gene did not eliminate the comets of NUDF and NUDA, but affected the behavior of NUDA. Comets were also observed with the green fluorescent protein-tagged NUDE and its nonfunctional C-terminal domain. In addition, overexpressed NUDA and NUDE accumulated in

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46

Jones, Stacy Holman, and Anne M. Harris. "(On the) Body as Book." Departures in Critical Qualitative Research 8, no. 3 (2019): 76–82. http://dx.doi.org/10.1525/dcqr.2019.8.3.76.

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Written in the spirit of Maggie Nelson's “autotheory,” this essay takes up José Esteban Muñoz's notion of “ephemera as evidence” to explore how the body-as-object (i.e., the body-as-book) might reformulate understandings of materiality as an ephemerality of “traces, glimmers, residues, and specks of things.” Bodies-as-books are distinctly material, though not always solid, and can be written and read as artifact-ephemera that end but do not disappear.

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47

Premi, B. R., Vijay Sethi, and D. B. Saxena. "Studies on identification of white specks in cured aonla (Emblica officinalis Gaertn.) fruits." Food Chemistry 61, no. 1-2 (1998): 9–11. http://dx.doi.org/10.1016/s0308-8146(97)00121-0.

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48

Stahl, Joan. "BRÜCKE: GERMAN EXPRESSIONIST PRINTS FROM THE GRANVIL AND MARCIA SPECKS COLLECTION. Reinhold Heller." Art Documentation: Journal of the Art Libraries Society of North America 8, no. 4 (1989): 209. http://dx.doi.org/10.1086/adx.8.4.27948147.

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49

Chen, Alice C.-H., Hai B. Tran, Yang Xi, et al. "Multiple inflammasomes may regulate the interleukin-1-driven inflammation in protracted bacterial bronchitis." ERJ Open Research 4, no. 1 (2018): 00130–2017. http://dx.doi.org/10.1183/23120541.00130-2017.

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Protracted bacterial bronchitis (PBB) in young children is characterised by prolonged wet cough, prominent airway interleukin (IL)-1β expression and infection, often with nontypeable Haemophilus influenzae (NTHi). The mechanisms responsible for IL-1-driven inflammation in PBB are poorly understood.We hypothesised that the inflammation in PBB involves the NLRP3 and/or AIM2 inflammasome/IL-1β axis. Lung macrophages obtained from bronchoalveolar lavage (BAL), peripheral blood mononuclear cells (PBMCs), blood monocytes and monocyte-derived macrophages from patients with PBB and age-matched healthy

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50

Compan, Vincent, Fátima Martín-Sánchez, Alberto Baroja-Mazo, et al. "Apoptosis-Associated Speck-like Protein Containing a CARD Forms Specks but Does Not Activate Caspase-1 in the Absence of NLRP3 during Macrophage Swelling." Journal of Immunology 194, no. 3 (2014): 1261–73. http://dx.doi.org/10.4049/jimmunol.1301676.

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