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Relevant bibliographies by topics / Spexine

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Journal articles

Academic literature on the topic 'Spexine'

Author: Grafiati

Published: 11 January 2025

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Journal articles on the topic "Spexine"

1

Lv, Shuangyu, Yuchen Zhou, Yu Feng, et al. "Peripheral Spexin Inhibited Food Intake in Mice." International Journal of Endocrinology 2020 (August 5, 2020): 1–9. http://dx.doi.org/10.1155/2020/4913785.

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Spexin (SPX, NPQ), a novel endogenous neuropeptide, was firstly identified by bioinformatics. Spexin gene and protein widely distributed in the central nervous system and peripheral tissues, such as the hypothalamus and digestive tract. The role of spexin in appetite regulation in mammalian is still unclear. The present study was designed to investigate the mechanism and effect of peripheral spexin on food intake in mice. During the light period, an intraperitoneal (i.p.) injection of spexin (10 nmol/mouse) significantly inhibited cumulative food intake at 2, 4, and 6 h after treatment in fast

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2

Liu, Ying, Di Wu, Hangping Zheng, et al. "Serum Spexin Level Is Negatively Associated With Peripheral Neuropathy and Sensory Pain in Type 2 Diabetes." Journal of Diabetes Research 2024 (May 23, 2024): 1–12. http://dx.doi.org/10.1155/2024/4538199.

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Background: Spexin is a novel peptide hormone and has shown antinociceptive effects in experimental mice. This study is aimed at evaluating the association of serum spexin level with diabetic peripheral neuropathy (DPN) and related pain in a Chinese population.Methods: We enrolled 167 type 2 diabetes mellitus (T2DM) including 56 patients without DPN (non-DPN), 67 painless DPN, and 44 painful DPN. Serum spexin was measured using ELISA. Logistic regression models were performed to analyze the independent effects of spexin on prevalence of DPN and painful DPN. In streptozotocin (STZ)-induced diab

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3

Karaca, Anara, Filiz Bakar-Ates, and Nese Ersoz-Gulcelik. "Decreased Spexin Levels in Patients with Type 1 and Type 2 Diabetes." Medical Principles and Practice 27, no. 6 (2018): 549–54. http://dx.doi.org/10.1159/000493482.

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Background/Aims: Spexin is a novel peptide which has a potential role as a biomarker of insulin resistance, diabetes, and obesity. Our aim was to measure spexin levels in lean type 1 diabetic patients and its relevance to glycemic parameters without the presence of obesity or insulin resistance. Subjects and Methods: This cross-sectional study included 29 type 1 and 30 type 2 diabetic patients and a control group of 23 healthy subjects with adjusted age, sex, and body mass index (BMI). Height and weight were measured using standard techniques. Glucose levels, triglycerides, total cholesterol,

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4

F. salih, Ruaa, Hala Abd Al-Qadir Al-Moayad Abd Al-Qadir Al-Moayad, Firas abbas, Jalil I. Alezzi, and Asrar Saleh Mohammed. "Association of Spexin Hormone Levels with Metabolic Disturbance in Women with Polycystic Ovarian Syndrome." Diyala Journal of Medicine 27, no. 1 (2024): 12–24. http://dx.doi.org/10.26505/djm.v27i1.1138.

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Background: Polycystic ovarian syndrome is affecting around 5–15% of females. Spexin hormone, identified as neuropeptide Q, has been newly recognized by bioinformatics methods. Objective: To evaluate the relationship concerning levels of spexin hormone with metabolic disruption in women with polycystic ovarian syndrome. Patients and Methods: A case-control study carried out in the department of Obstetrics and Gynecology in Al-Imamain Al-Khademain medical city/Baghdad, Iraq, from Jan 1, 2022, to the end of Dec 31, 2022. The study sample comprises, 192 participants aged 18-45 years were joined a

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5

Bacopoulou, Flora, Despoina Apostolaki, Aimilia Mantzou, et al. "Serum Spexin is Correlated with Lipoprotein(a) and Androgens in Female Adolescents." Journal of Clinical Medicine 8, no. 12 (2019): 2103. http://dx.doi.org/10.3390/jcm8122103.

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The Spexin gene is considered the most dysregulated in obese human fat. Limited data suggest that the novel peptide spexin may potentially impact food intake, weight regulation and body adiposity. The aim of this case-control study was to compare fasting serum spexin concentrations between normal weight (NW) and overweight/obese (OB/OW) adolescent females and explore the relationship between circulating spexin and anthropometric, bone and fat mass, metabolic and hormonal parameters. Eighty post-menarcheal females (mean age ± SD 16.23 ± 2.26 years); 55 NW (mean BMI ± SD 19.72 ± 2.52 kg/m2) and

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6

Ozturk Onsal, Fatma Duygu, Ahmet Ucar, Ali Bulbul, Zeynep Yildiz Yildirmak, and Gizem Kara Elitok. "Associations of Size at Birth and Metabolic Syndrome Antecedents With Serum Spexin Levels in Prepubertal Children." Journal of the Endocrine Society 5, Supplement_1 (2021): A709—A710. http://dx.doi.org/10.1210/jendso/bvab048.1445.

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Abstract Background: Spexin is a novel peptide implicated in food intake and obesity. The primary aim of this study was to analyze whether serum spexin levels, along with total leptin and active ghrelin levels were different in prepubertal children born small for gestational age(SGA) and appropriate for gestational(AGA). Secondary aims were to analyze whether serum spexin, leptin and active ghrelin levels correlated with metabolic syndrome(MS)antecedents according to the Dietary and lifestyle-induced health effects in children and infants (IDEFICS)study. Subjects and Methods: We conducted a cr

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7

Cichoń, Lena, Artur Pałasz, Krzysztof M. Wilczyński, et al. "Evaluation of Peripheral Blood Concentrations of Phoenixin, Spexin, Nesfatin-1 and Kisspeptin as Potential Biomarkers of Bipolar Disorder in the Pediatric Population." Biomedicines 12, no. 1 (2023): 84. http://dx.doi.org/10.3390/biomedicines12010084.

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There are some initial suggestions in the literature that phoenixin, spexin, nesfatin-1 and kisspeptin may play a role in the pathogenesis of affective disorders. Therefore, they may also be cautiously considered as potential diagnostic or predictive biomarkers of BD. This study aimed to evaluate the levels of the aforementioned neuropeptides in the peripheral blood of children and adolescents with bipolar. This study included 122 individuals: 67 persons with diagnosed bipolar disorder types I and II constituted the study group, and 55 healthy persons were included in the control group. Statis

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8

Yazgan, Burak, Filiz Avcı, Gülsün Memi, and Ebru Tastekin. "Inflammatory response and matrix metalloproteinases in chronic kidney failure: Modulation by adropin and spexin." Experimental Biology and Medicine 246, no. 17 (2021): 1917–27. http://dx.doi.org/10.1177/15353702211012417.

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Chronic kidney disease is a major global public health problem. The peptide hormones adropin and spexin modulate many physiological functions such as energy balance and glucose, lipid and protein metabolism. However, it is unclear whether these peptides may exert effects on renal damage, tissue remodeling, and inflammatory conditions. In view of the limited information, we aimed to investigate the effect of adropin and spexin on matrix metalloproteinase and inflammatory response genes a rat model of adenine-induced chronic kidney failure. Chronic kidney failure was induced in rats by administe

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9

Ghannawi,, L. A., K. Gharab,, M. A. Hadi,, O. Y. Shakir,, and A. M. Rahmah. "Spexin level in growth hormone deficiency Iraqi children." Ukrainian Biochemical Journal 96, no. 4 (2024): 55–61. http://dx.doi.org/10.15407/ubj96.04.055.

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Spexin (SPX) is a newly discovered brain adipokine implicated in various homeostatic functions including metabolism, energy balance, endocrine processes and growth hormone (GH) production in particular. At the same time, the growth-promoting effects of GH are influenced by Insulin-like growth factor-1 (IGF‑1) and vitamin D3. The aim of this study was to investigate the possible involvement of SPX in growth hormone deficiency (GHD) in children. The research involved 90 children (40 with growth hormone deficiency and 50 healthy controls aged 5-14). Serum levels of GH, IGF and vitamin D3 were tes

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10

Abdualhay, Raghda Abdulsamad, and Adnan Jassim Mohammed Al-Fartosy. "Insulin Resistance and Other Adipokines as Clinical Predictors of Gestational Diabetes Mellitus among Pregnant Women." Indonesian Biomedical Journal 14, no. 3 (2022): 243–51. http://dx.doi.org/10.18585/inabj.v14i3.1934.

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BACKGROUND: Gestational diabetes mellitus (GDM) has a strong relationship with an increased risk of maternal and perinatal complications. However, in Basrah, Iraq, studies regarding GDM are still limited. In current study, we aimed to investigate the association between insulin resistance and some clinical predictors of GDM among pregnant women in 1st and 3rd trimesters of gestation.METHODS: This case-control study was conducted on 44 pregnant women with GDM and 45 without GDM aged 20 to 40 years who applied for GDM screening during the first (9-13 week) and third trimester (24-28 week) of pre

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