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Journal articles on the topic 'Sphingomonas; diagnosis'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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1

Hüseyin, ÇAKAR, and YILMAZ Sevdan. "IN VITRO ANTAGONISTIC EFFECT OF GRAM-NEGATIVE PROBIOTIC BACTERIA AGAINST FISH PATHOGENS." Aquatic Animal Reports 1, no. 1 (2023): 9–16. https://doi.org/10.5281/zenodo.7660335.

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<strong>Abstract</strong> The idea of this study is to investigate the antagonistic effect of <em>Sphingomonas</em> spp. against fish pathogens. The liquid culture inhibition test analysis showed that <em>Sphingomonas </em>spp. has an antagonistic effect on <em>Lactococcus garvieae </em>SY-LG1. However, the effect has not been fully observed on <em>Aeromonas salmonicida</em> subsp. <em>salmonicida</em> ATCC 33658, <em>Yersinia ruckeri </em>E42,<em> Vibrio (Listonella) anguillarum </em>and <em>Vibrio crassostreae </em>SY-VC10. In this study, the effect of <em>Sphingomonas </em>spp. on fish path

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Sofoudis, Chrisostomos. "Sphingomonas paucimobilis complicating vaginal fluid cultivation. A rare case." Cancer Research and Cellular Therapeutics 5, no. 1 (2021): 01–03. http://dx.doi.org/10.31579/2640-1053/071.

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Sphingomonas paucimobilis represents an aerobic Gram-negative bacillus that is gaining recognition as an important human pathogen. These species are widely distributed in both natural environment and hospitals. They appear as opportunistic pathogen that take advantage of underlying conditions and diseases. Regardless of the clinical significance, pathogenic mechanism varies throughout current bibliography. Aim of our study, reflects presentation of a rare case of an out-patient clinical asymptomatic, with vaginal culture positive for this rare microorganism, S. paucimobilis. Assiduous diagnosi

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3

Rinawati, Weny, and July Kumalawati. "Sphingomonas paucimobilis infection in subcutaneous abdominal preservation of bone flap after craniotomy." Journal of Infection in Developing Countries 16, no. 02 (2022): 388–91. http://dx.doi.org/10.3855/jidc.15369.

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Introduction: Sphingomonas paucimobilis, previously known as Pseudomonas paucimobilis, is a Gram-negative rod. It is emerging as an opportunistic pathogen that can infect individuals in community or hospital settings. It is believed that the natural habitat of this organism is soil and water, including water sources in the hospital environment. Case report: We describe the case of a 46-year-old patient in whom S. paucimobilis was identified in the implanted bone flap after craniotomy. The postoperative bone flap was implanted in the right hypochondria and replaced after 8 weeks. There wa

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Murtafi'ah, Ni'matul, Ally Kafesa, and Aziz Ansori Wahid. "Molecular identification of the bacterium acute conjunctivitis by the method of sequensing gen 16S rRNA." Indonesian Journal of Medical Laboratory Science and Technology 6, no. 1 (2024): 44–54. http://dx.doi.org/10.33086/ijmlst.v6i1.5207.

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Conjunctivitis is the most common eye disease, characterized by contextual inflammation, which can be caused by bacteria. The diagnosis of conjunctivitis is established based various factors, including the patients’s medical history, onset of eye symptoms, non-ocular symptoms, previous disease history, family medical history, allergies, and physical examination of the eyes, which may include assessments of visual acuity and vision field. Some cases of conjunctivitis require laboratory examinations to confirm the diagnosis. These may include cytological examination with Giemsa staining, Chlamyd

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Hussein, Nadheema Hammood, Israa M. S. AL-Kadmy, Suhad Abbas Abid, et al. "Detection of NDM-1 harboring Moraxella lacunata and Sphingomonas paucimobilis: first report from Iraq." Reviews and Research in Medical Microbiology 35, no. 4 (2023): 212–17. http://dx.doi.org/10.1097/mrm.0000000000000362.

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Background and aim: This study aimed to detect New Delhi metallo-beta-lactamase 1 (NDM-1) harboring Moraxella lacunata and Sphingomonas paucimobilis for the first time in Iraq. Material and methods: One hundred and sixty-nine bacterial isolates were collected from blood samples in Baghdad children hospital. Two bacterial species based on the selection of carbapenem will be reported for this study. The results are confirmed by conventional PCR and detection about NDM-1 gene that responsible of carbapenemases resistance. Results: Three isolates (one M. lacunata and two S. paucimobilis) were resi

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Cornejo, Angela, Claudia Gomes, Luis Suarez, et al. "An unidentified cluster of infection in the Peruvian Amazon region." Journal of Infection in Developing Countries 9, no. 05 (2015): 524–29. http://dx.doi.org/10.3855/jidc.6235.

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Introduction: Bartonella bacilliformis is the etiological agent of Carrion’s disease, which is a neglected disease linked to people in low-socioeconomic populations in Andean valleys. An outbreak of B. bacilliformis was reported in a rural area of the Peruvian Amazon region. The aim of this study was to characterize this outbreak using molecular techniques. Methodology: Fifty-three blood samples from patients diagnosed with Carrion’s disease were analyzed by molecular tools, using both a Bartonella-specific polymerase chain reaction (PCR) and an universal PCR, both based on 16S rRNA gene ampli

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Edan, Dhay J., Munther Abduljaleel Muhammad-Ali, and Raghad Shubbar Jaafar. "Combined Efficacy of Lawsonia inermis and Myrtus communis Extract as a Potential Factor in Bacterial Treatment to Hospital Wastewater, Iraq." IOP Conference Series: Earth and Environmental Science 1215, no. 1 (2023): 012008. http://dx.doi.org/10.1088/1755-1315/1215/1/012008.

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Abstract The current study aimed to use biological treatment using plant extracts; extracted from some locally available plants: Lawsonia inermis (Henna), and Myrtus communis (Yass), against pathogenic bacteria isolated from heavy water in hospitals that do not have treatment plants. The two studied plants were extracted using two different solvents (water and alcohol). Diagnosis of these extracted using Gas chromatography (GC-MS) showed that the alcoholic extraction led to a higher percentage of effective phenolic compounds than the aqueous extract. Sewage water was used to isolate bacteria a

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Elvas, Ana Rita, Bruno Jorge Pereira, Filipa Carrega, and Leopoldina Vicente. "Pielonefrite Enfisematosa Fulminante Secundária a Neoplasia Urotelial com Fístula Renocólica." Acta Médica Portuguesa 31, no. 2 (2018): 129. http://dx.doi.org/10.20344/amp.8869.

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The emphysematous pyelonephritis is a uncommon and potentially fatal entity. The recognition of this condition enables the early correct management of patients. Diabetes and ureteral obstruction are the main risk factors identified. We present the case of a patient with no relevant risk factors or prior medical history, in which the reason of admission to the emergency department was back pain, eventually evolving into septic shock in the early hours. The imaging tests identified the presence of peri-renal and subcutaneous gas which guided the medical team to the right diagnosis (emphysematous

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9

Kim, Jae Ri, Kyulhee Han, Youngmin Han, et al. "Microbiome Markers of Pancreatic Cancer Based on Bacteria-Derived Extracellular Vesicles Acquired from Blood Samples: A Retrospective Propensity Score Matching Analysis." Biology 10, no. 3 (2021): 219. http://dx.doi.org/10.3390/biology10030219.

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Novel biomarkers for early diagnosis of pancreatic cancer (PC) are necessary to improve prognosis. We aimed to discover candidate biomarkers by identifying compositional differences of microbiome between patients with PC (n = 38) and healthy controls (n = 52), using microbial extracellular vesicles (EVs) acquired from blood samples. Composition analysis was performed using 16S rRNA gene analysis and bacteria-derived EVs. Statistically significant differences in microbial compositions were used to construct PC prediction models after propensity score matching analysis to reduce other possible b

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Petrov, V. A., V. M. Alifirova, I. V. Saltykova, et al. "Diagnostic potential of gut microbiota in Parkinson’s disease." Bulletin of Siberian Medicine 18, no. 4 (2020): 92–101. http://dx.doi.org/10.20538/1682-0363-2019-4-92-101.

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Background. Nowadays many efforts are taken in searching for Parkinson’s disease biomarkers, especially for an early recognition of the disease. The gut microbiota is one of the potential sources of biomarkers, changes in the composition of which in PD are actively studied.The aim of this study is to identify microbiota biomarkers in the Parkinson’s disease with an estimated accuracy of the diagnostics, including differential diagnostics, relative to other neurological diseases for patients of the Russian population.Material and methods. One hundred ninety-two metagenomics profiles from patien

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Muwafaq Azeez, Iman, and Mohammed Nather Maa'roof. "Isolation and Identification of some Bacterial Species From Cervix Infected Women in Salahuddin Governorate." Tikrit Journal of Pharmaceutical Sciences 13, no. 1 (2023): 44–53. http://dx.doi.org/10.25130/tjphs.2018.13.1.7.44.53.

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This study was carried out for isolating some pathogenic types of positive and negative bacteria for Gram stain, which cause the infection of the vaginitis in infected women and its diagnosis by routine laboratory methods and confirm the diagnosis using Vitek2compact system by collecting fifty samples of the swab of the cervix in the period between October 2015 till April 2016 from the in patients and out patients women in Salahuddin Hospital for the age groups between (14-50) years.The results of isolation show the percentage of bacterial growth was 78%, it reached samples in 78%.The results

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Jo, YoungJae, Da-Ryung Jung, Tae-Hyung Park, et al. "Changes in Microbial Community Structure in Response to Gummosis in Peach Tree Bark." Plants 11, no. 21 (2022): 2834. http://dx.doi.org/10.3390/plants11212834.

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Peach gummosis disease has been identified as a serious challenge in Korean agriculture and has developed to become a major cause of agricultural productivity losses. However, treatments for gummosis have not been systemically established and studies of the microbiome closely related to this plant disease are lacking. Therefore, we analyzed the bacterial and fungal communities in the bark and rhizosphere soil of healthy peach trees and those with gummosis. Through high-throughput sequencing, we obtained unprecedented insights into the bacterial and fungal dynamics of each group, including thei

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Akhtar, Shahida, Asifa Nazir, and Humaira Bashir. "Aerobic bacteriological analysis of bronchoalveolar lavage fluid in patients with pulmonary infection: a tertiary care hospital study." International Journal of Research in Medical Sciences 9, no. 3 (2021): 833. http://dx.doi.org/10.18203/2320-6012.ijrms20210887.

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Background: Respiratory tract infection are an important cause of mortality and morbidity worldwide. The prevalent bacterial agents and their antimicrobial resistance patterns differs, both geographically and over time. Bronchoalveolar lavage has improved sensitivity and specificity of diagnostic techniques in diagnosis of pulmonary infections. The present study aimed to determine the current aerobic bacterial isolates and their sensitivity pattern obtained from the bronchoalveolar lavage (BAL) fluid of patients with pulmonary infection.Methods: BAL samples received from the patients of suspec

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Kyaw, Aung Kyaw, Ohnmar, Zin Nwe Win, et al. "Etiology, Clinical Profiles, and Outcomes of Acute Encephalitis Syndrome Cases Admitted to a Tertiary Care Center in Myanmar in 2023." Diagnostics 14, no. 19 (2024): 2248. http://dx.doi.org/10.3390/diagnostics14192248.

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Background/Objectives: The diagnosis of encephalitis is a challenging problem due to the heterogeneity of clinical presentations. The objective was to determine the etiology, clinical features, laboratory parameters, radiological findings, and in-hospital outcome of acute encephalitis syndrome (AES) cases in Myanmar. Methods: A prospective descriptive study was conducted at the Neuromedical Ward of Yangon General Hospital from March to August 2023. Eighty-one AES cases were enrolled, and cerebrospinal fluid (CSF) samples were collected. A Qiastat ME Panel was used to detect viral, bacterial, a

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Marincu, Iosif, Felix Bratosin, Iulia Bogdan, et al. "Concurrent Sphingomonas paucimobilis and Mycobacterium tuberculosis Meningitis in an Immunocompromised Patient: A Rare Case Report and Comprehensive Review of Literature." Medicina 59, no. 4 (2023): 687. http://dx.doi.org/10.3390/medicina59040687.

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Sphingomonas paucimobilis is a gram-negative bacillus that is widely distributed in the environment but rarely causes infections in humans. Meningitis caused by S. paucimobilis is an extremely rare clinical entity with very few reported cases in the literature. The clinical presentation and management of S. paucimobilis meningitis are not well established, and further research is needed to better understand this rare infection. Therefore, the goal of this study was to present probably the only case of meningitis caused by co-infection with S. paucimobilis and Mycobacterium tuberculosis and to

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Li, Xiang, Yifan Tang, Zhenyi Xu, et al. "Impact of coexisting type 2 diabetes mellitus on the urinary microbiota of kidney stone patients." PeerJ 12 (February 26, 2024): e16920. http://dx.doi.org/10.7717/peerj.16920.

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Objectives Type 2 diabetes mellitus (T2DM) commonly complicates kidney stone disease (KSD). Our objective is to investigate the variations in the urinary microbiota between individuals with KSD alone and those with KSD plus T2DM. This exploration could have implications for disease diagnosis and treatment strategies. Methods During lithotripsy, a ureterscope was employed, and 1 mL of urine was collected from the renal pelvis after bladder disinfection. Sequencing targeting the V3–V4 hypervariable region was performed using the 16S rRNA and Illumina Novaseq platform. Results The Shannon index s

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Khan, Sheema, Goutam Banerjee, Saini Setua, et al. "Abstract 2178: Metagenomic analysis unveils the microbial landscape of pancreatic tumors." Cancer Research 84, no. 6_Supplement (2024): 2178. http://dx.doi.org/10.1158/1538-7445.am2024-2178.

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Abstract The composition of resident microbes in the human body is linked to various diseases and their treatment outcomes. Although studies have identified pancreatic ductal adenocarcinoma (PDAC) associated bacterial communities in the oral and gut samples, herein we hypothesize the prevalence of microbiota in pancreatic tumor tissues is different as compared to their matched adjacent, histologically normal appearing tissues and these microbial molecular signatures can be highly useful for PDAC diagnosis/prognosis. In this study, we performed comparative profiling of bacterial populations in

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Kartti, Souad, Houda Bendani, Nasma Boumajdi, et al. "Metagenomics Analysis of Breast Microbiome Highlights the Abundance of Rothia Genus in Tumor Tissues." Journal of Personalized Medicine 13, no. 3 (2023): 450. http://dx.doi.org/10.3390/jpm13030450.

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Breast cancer is one of the main global priorities in terms of public health. It remains the most frequent cancer in women and is the leading cause of their death. The human microbiome plays various roles in maintaining health by ensuring a dynamic balance with the host or in the appearance of various pathologies including breast cancer. In this study, we performed an analysis of bacterial signature differences between tumor and adjacent tissues of breast cancer patients in Morocco. Using 16S rRNA gene sequencing, we observed that adjacent tissue contained a much higher percentage of the Gamma

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Varadarajan, Prakash, Juan Toro, Robert M. Craig, et al. "Does Bisphosphonate-Induced Osteonecrosis of the Jaw (BONJ) Preclude Intensive Chemotherapy? Oral and Infectious Toxicities Associated with Autotransplantation In Patients with BONJ." Blood 116, no. 21 (2010): 1314. http://dx.doi.org/10.1182/blood.v116.21.1314.1314.

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Abstract Abstract 1314 Background: Bisphosphonate-induced osteonecrosis of the jaw (BONJ) is a recently recognized adverse reaction associated with intravenous bisphosphonate use. The incidence of BONJ is estimated to be between 5–15% of patients with multiple myeloma (MM) treated with biphosphonates. Relevant to this complication, areas of osteonecrosis can harbor bacteria with the potential to cause infection and bacteremia during prolonged periods of myelosuppression. Furthermore, it is unclear if BONJ can worsen mucositis associated with cytotoxic therapy or if intensive chemotherapy can i

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Dsouza, Areena, Abhinandan Reddy Mallepally, Nandan Amrit Marathe, Kalidutta Das, and Bibhudendu Mohaptra. "A Rare Case of Sphingomonas paucimobilis Spondylodiscitis Managed Surgically." JOURNAL OF ORTHOPAEDIC CASE REPORTS 11, no. 4 (2021). http://dx.doi.org/10.13107/jocr.2021.v11.i04.2166.

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Introduction: Sphingomonas paucimobilis is an opportunistic pathogen and a rare cause of human infection. This case report shows bacteremia with pyogenic spondylodiscitis in lumbosacral spine caused by Sphingomonas and discusses its clinical diagnosis, treatment, and literature reviews. Case Report: Patient presented with severe low back pain, inability to walk and fever following a L5-S1 decompression elsewhere, which corresponded clinico-radiologically with a picture of a spondylodiscitis on radiographs, magnetic resonance imaging, and computed tomography. His blood culture was positive for

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Cornejo, Tapia Ángela, Cláudia Gomes, Ognio Luis Suárez, et al. "An unidentified cluster of infection in the Peruvian Amazon region." Journal of Infection in Developing Countries (J Infect Dev Ctries.), May 21, 2015. https://doi.org/10.3855/jidc.6235.

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Introduction: Bartonella bacilliformis is the etiological agent of Carrion’s disease, which is a neglected disease linked to people in low-socioeconomic populations in Andean valleys. An outbreak of B. bacilliformis was reported in a rural area of the Peruvian Amazon region. The aim of this study was to characterize this outbreak using molecular techniques. Methodology: Fifty-three blood samples from patients diagnosed with Carrion’s disease were analyzed by molecular tools, using both a Bartonella-specific polymerase chain reaction (PCR) and an universal PCR, both based on 16S rRN

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Alyousef, Mohammed, Ahmad Alroqi, and Nouf AlAmari. "Atrophic Rhinitis Secondary to an Infection of Unusual Bacteria: A Case Report and Literature Review." Ear, Nose & Throat Journal, September 16, 2022, 014556132211150. http://dx.doi.org/10.1177/01455613221115048.

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Clinically, atrophic rhinitis (AR) is well recognized. We present the case of a patient diagnosed with AR. Sphingomonas paucimobilis, an uncommon bacterial pathogen, has been isolated in nasal cultures. This study discusses the microorganisms, causing AR. According to previous research, these infections have been associated with significant morbidity and mortality. Due to the limited knowledge on the disease, the diagnosis is frequently delayed. Thus, frequent monitoring and treatment are needed to avoid complications. This rare type of infection should be suspected in patients presenting with

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Figueiredo, Caio C., Hugo F. Monteiro, Federico Cunha, et al. "Shifts in uterine microbiome associated with pregnancy outcomes at first insemination and clinical cure in dairy cows with metritis." Scientific Reports 14, no. 1 (2024). http://dx.doi.org/10.1038/s41598-024-61704-0.

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AbstractObjectives were to assess differences in uterine microbiome associated with clinical cure and pregnancy outcomes in dairy cows treated for metritis. Cows with metritis (reddish-brownish, watery, and fetid vaginal discharge) were paired with cows without metritis based on parity and days postpartum. Uterine contents were collected through transcervical lavage at diagnosis, five days later following antimicrobial therapy (day 5), and at 40 days postpartum. Uterine microbiome was assessed by sequencing the V4 hypervariable region of the 16S rRNA gene. Although alpha-diversity based on Cha

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Khan, Sheema, Goutam Banerjee, Saini Setua, et al. "Metagenomic analysis unveils the microbial landscape of pancreatic tumors." Frontiers in Microbiology 14 (December 21, 2023). http://dx.doi.org/10.3389/fmicb.2023.1275374.

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The composition of resident microbes in the human body is linked to various diseases and their treatment outcomes. Although studies have identified pancreatic ductal adenocarcinoma (PDAC)-associated bacterial communities in the oral and gut samples, herein, we hypothesize that the prevalence of microbiota in pancreatic tumor tissues is different as compared with their matched adjacent, histologically normal appearing tissues, and these microbial molecular signatures can be highly useful for PDAC diagnosis/prognosis. In this study, we performed comparative profiling of bacterial populations in

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Ren, Zhichao, Wenfeng Li, Qing Liu, Yanling Dong, and Yusen Huang. "Profiling of the Conjunctival Bacterial Microbiota Reveals the Feasibility of Utilizing a Microbiome-Based Machine Learning Model to Differentially Diagnose Microbial Keratitis and the Core Components of the Conjunctival Bacterial Interaction Network." Frontiers in Cellular and Infection Microbiology 12 (April 26, 2022). http://dx.doi.org/10.3389/fcimb.2022.860370.

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Both healthy and diseased human ocular surfaces possess their own microbiota. If allowed, opportunistic pathogens within the ocular microbiota may cause microbial keratitis (MK). However, the nonpathogenic component of the ocular microbiota has been proven to undermine the performance of culture, the gold standard of the etiological diagnosis for MK. As the conjunctival bacterial microbiota generates unique alterations with various oculopathies, this study aimed to evaluate the feasibility of distinguishing MK using machine learning based on the characteristics of the conjunctival bacterial mi

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Ren, Zhichao, Wenfeng Li, Qing Liu, Yanling Dong, and Yusen Huang. "Profiling of the Conjunctival Bacterial Microbiota Reveals the Feasibility of Utilizing a Microbiome-Based Machine Learning Model to Differentially Diagnose Microbial Keratitis and the Core Components of the Conjunctival Bacterial Interaction Network." Frontiers in Cellular and Infection Microbiology 12 (April 26, 2022). http://dx.doi.org/10.3389/fcimb.2022.860370.

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Both healthy and diseased human ocular surfaces possess their own microbiota. If allowed, opportunistic pathogens within the ocular microbiota may cause microbial keratitis (MK). However, the nonpathogenic component of the ocular microbiota has been proven to undermine the performance of culture, the gold standard of the etiological diagnosis for MK. As the conjunctival bacterial microbiota generates unique alterations with various oculopathies, this study aimed to evaluate the feasibility of distinguishing MK using machine learning based on the characteristics of the conjunctival bacterial mi

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Guo, Linlin, Ruoming Wang, Liping Han, et al. "Multi-omics integration identifies key biomarkers in retinopathy of prematurity through 16S rRNA sequencing and metabolomics." Frontiers in Microbiology 16 (June 18, 2025). https://doi.org/10.3389/fmicb.2025.1601292.

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BackgroundThe gut microbiome is increasingly recognized for its role in the pathogenesis of neonatal conditions commonly associated with retinopathy of prematurity (ROP). This study aimed to identify key intestinal microbiota and metabolites in ROP and examine their relationships.MethodsFecal samples were collected from infants with and without ROP at weeks 2 (T1) and 4 (T2) for 16S rRNA sequencing. At T2, additional fecal samples underwent non-targeted metabolomic analyses. A combined analysis of the 16S rRNA sequencing and metabolomics data was performed.ResultsNo significant differences in

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Singh, Sweta, Chinmoy Sahu, and Sangram Singh Patel. "Rare and Under Reported Causes of Bacteremia: Case Series from a Tertiary Health Care Centre of Northern India." JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2020. http://dx.doi.org/10.7860/jcdr/2020/44536.13818.

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With increasing medical interventions, immunosuppressants, hospital stay and antibiotic use; people are finding increased cases of hospital acquired infections. Bacteremia and sepsis are important cause of morbidity and mortality in tertiary health care centres. Majority of bacteremia are caused by the Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa and Enterobacter spp (ESKAPE) pathogens. However, in some cases hospital environment bacteria can cause bacteremia and sepsis, especially in immunocompromised patients. Each bacter

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Yu, Zengxian, Fang Zhu, Xinghe Tao, et al. "Vogesella perlucida-induced bacteremia in an advanced-age patient: first case report." BMC Infectious Diseases 20, no. 1 (2020). http://dx.doi.org/10.1186/s12879-020-05420-w.

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Abstract Background Vogesella species are common aquatic, Gram-negative rod-shaped bacteria, originally described in 1997. Vogesella perlucida was first isolated from spring water in 2008. Furthermore, bacterial pathogenicity of Vogesella perlucida has never been reported. Here, we report the first case of rare Vogesella perlucida-induced bacteremia in an advanced-age patient with many basic diseases and history of dexamethasone abuse. Case presentation A 71-year-old female was admitted with inflamed upper and lower limbs, rubefaction, pain and fever (about 40 °C). She had been injured in a fa

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Yoon, Hee-Young, Su-Jin Moon, and Jin Woo Song. "Lung Tissue Microbiome Is Associated With Clinical Outcomes of Idiopathic Pulmonary Fibrosis." Frontiers in Medicine 8 (October 18, 2021). http://dx.doi.org/10.3389/fmed.2021.744523.

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Background: Several studies using bronchoalveolar lavage fluid (BALF) reported that lung microbial communities were associated with the development and clinical outcome of idiopathic pulmonary fibrosis (IPF). However, the microbial communities in IPF lung tissues are not well known. This study is aimed to investigate bacterial microbial communities in lung tissues and determine their impact on the clinical outcomes of patients with IPF.Methods: Genomic DNA extracted from lung tissues of patients with IPF (n = 20; 10 non-survivors) and age- and sex-matched controls (n = 20) was amplified using

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Shi, Bo, Fei Chen, Jianmin Gong, et al. "Urinary microbiome profiling as a non-invasive tool for identifying biomarkers in systemic lupus erythematosus and lupus nephritis." Frontiers in Cellular and Infection Microbiology 14 (December 3, 2024). https://doi.org/10.3389/fcimb.2024.1364333.

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IntroductionBacteriome alterations have been implicated in the pathogenesis of systemic lupus erythematosus (SLE). However, the relationship between SLE and the urinary microbiome remains underexplored. This study aimed to characterize the urinary microbiome of SLE patients using 16S rRNA sequencing and to investigate its correlations with clinical parameters through integrative analyses.MethodsUrine sediment samples were collected from individuals with SLE and lupus nephritis (LN) (n = 20), SLE without LN (n = 22), and healthy controls (HCs) (n = 23). DNA was extracted and subjected to 16S rR

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Weslander, Erin, Joshua D. Doyle, Andrew Nowalk, and Michael Bykowski. "1322. Infectious Complications Following Pediatric Lawn Mower Injury: A Case Series." Open Forum Infectious Diseases 9, Supplement_2 (2022). http://dx.doi.org/10.1093/ofid/ofac492.1152.

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Abstract Background According to the National Electronic Injury Surveillance System, there are an estimated 9,400 riding lawn mower injuries in the United States in pediatric patients per year. Previous case series report a 7-12.5% infection rate after injury. We report our experience of lawn mower injury-related infections over a 4-year period. Methods Cases of lawn mower injury at our center were identified by the ICD-10 code W28.XXXA for contact with a powered lawn mower between 2017-2020. Patient demographics, injury background, microbial results, and antimicrobial use were collected via m

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Orababa, Oluwatosin Qawiyy, Solayide A. Adesida, Rebecca F. Peters, Zainab AbdulGanniyu, Olawale Olakojo, and Adefunke Abioye. "Showing the limitations of available phenotypic assays to detect Burkholderia pseudomallei from clinical specimens in Nigeria." Access Microbiology 5, no. 10 (2023). http://dx.doi.org/10.1099/acmi.0.000604.v5.

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The genus Burkholderia comprises Gram-negative bacteria that are metabolically complex and versatile, often thriving in hostile settings. Burkholderia pseudomallei , the causative agent of melioidosis, is a prominent member of the genus and a clinical pathogen in tropical and sub-tropical regions. This pathogen is well known for its multidrug resistance and possible bioweapon potential. There is currently no report of the pathogen from clinical specimens in Nigeria, which might be due to misdiagnosis with phenotypic assays. This study aims to explore the accuracy of the use of phenotypic assay

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