Academic literature on the topic 'Spiked Pharmaceutical Liquid Waste'

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Journal articles on the topic "Spiked Pharmaceutical Liquid Waste"

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Trucillo, Paolo, Roberta Campardelli, and Iolanda De Marco. "Environmental and Sustainability Analysis of a Supercritical Carbon Dioxide-Assisted Process for Pharmaceutical Applications." Processes 9, no. 10 (2021): 1788. http://dx.doi.org/10.3390/pr9101788.

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Drug delivery systems (DDS) are artificial devices employed to enhance drug bioavailability during administration to a human body. Among DDS, liposomes are spherical vesicles made of an aqueous core surrounded by phospholipids. Conventional production methods are characterized by several drawbacks; therefore, Supercritical assisted Liposome formation (SuperLip) has been developed to overcome these problems. Considering that the use of high pressures involves high energy cost, in this paper, sustainability indicators were calculated to quantitatively evaluate the emissions related to the attain
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SÜsÜl, İncilay, and Sacide AltinÖz. "A Reversed-Phase High-Performance Liquid Chromatographic Method for the Determination of Zafirlukast in Pharmaceutical Formulations and Human Plasma." Journal of AOAC INTERNATIONAL 89, no. 6 (2006): 1557–64. http://dx.doi.org/10.1093/jaoac/89.6.1557.

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Abstract Zafirlukast (ZAF) is a leukotriene receptor antagonist used in the treatment of chronic asthma. In this study, a simple and sensitive reversed-phase, high-performance liquid chromatographic method was developed for the determination of ZAF in pharmaceutical formulations and human plasma. Piribedil was used as an internal standard. Analysis was carried out on a Nucleosil C18 100 Å(150 × mm 4.6 mm id, 5 ωm) column with acetonitrilepH 3.0 acetate buffer (70 30, v/v) as the mobile phase at a flow rate of 0.8 mL/min. The peak was detected by an ultraviolet detector set at a wavelength of 2
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Ni, Baoxia, Jin Ye, Zhihong Xuan, et al. "Automatic Pretreatment of Dispersive Liquid Liquid Microextraction Based on Immunomagnetic Beads Coupled with UPLC-FLD for the Determination of Zearalenone in Corn Oils." Toxins 15, no. 5 (2023): 337. http://dx.doi.org/10.3390/toxins15050337.

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Sample pretreatment is a vital step in the detection of mycotoxins, and traditional pretreatment methods are time-consuming, labor-intensive and generate much organic waste liquid. In this work, an automatic, high-throughput and environmentally friendly pretreatment method is proposed. Immunomagnetic beads technology and dispersive liquid–liquid microextraction technology are combined, and the zearalenone in corn oils is directly purified and concentrated under the solubilization effects of surfactant. The proposed pretreatment method allows for the batch pretreatment of samples without pre-ex
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Ceccon, Luciano, Debora Saccù, Giuseppe Procida, and Stefano Cardinali. "Liquid Chromatographic Determination of Simple Phenolic Compounds in Waste Waters from Olive Oil Production Plants." Journal of AOAC INTERNATIONAL 84, no. 6 (2001): 1739–44. http://dx.doi.org/10.1093/jaoac/84.6.1739.

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Abstract A method was developed for the determination of simple phenolic compounds (PCs) in waste waters from olive oil production plants by liquid chromatography (LC). The sample under examination was acidified to pH 2 to precipitate proteins, acetone was added to eliminate the colloidal fraction, and hexane was used for extraction to eliminate lipidic substances. The solution obtained was filtered and injected into the LC system; the wavelength selected for the spectrophotometric detection was specific for PCs, so that carbohydrates, organic acids, and short-chain free fatty acids did not in
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Faizee, A., S. S. Sonawane, A. S. Patil, S. J. Kshirsagar, and V. S. Gade. "DEVELOPMENT OF LIQUID-LIQUID EXTRACTION PROCEDURE AND ITS APPLICATION FOR QUANTIFICATION OF ERLOTINIB IN SPIKED HUMAN PLASMA USING RP-HPLC WITH UV DETECTION." INDIAN DRUGS 53, no. 06 (2016): 46–50. http://dx.doi.org/10.53879/id.53.06.10498.

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A simple, rapid and accurate RP-HPLC method was developed and validated for the quantification of Erlotinib in spiked human plasma using liquid-liquid extraction. Sufficient recovery was obtained when drug and internal standard (Nabumetone) were extracted using ethyl acetate and 1N NaOH. Chromatographic separation was performed on C18 Phenomenex Hyperclone column (250 × 4.6 mm, 5 μm) using mobile phase acetonitrile: 20 mM ammonium acetate buffer pH 4.6 (60:40%,V/V). Flow rate was kept constant at 1 mL/min and detection was carried out at 331 nm. Calibration curve was found to be linear in the
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Abed, Sadeem Subhi, and Mayasa Mansour Mohammed. "Spectrophotometric and cloud point extraction methods to detect Quercetin Dihydrate in supplement formulations and urine samples." Ukrainian Journal of Nephrology and Dialysis, no. 4(84) (October 15, 2024): 75–85. https://doi.org/10.31450/ukrjnd.4(84).2024.09.

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The accurate detection and quantification of quercetin dihydrate (QRC) are vital for quality control, pharmacokinetic studies, and bioavailability assessments in pharmaceutical and biological samples. This study aimed to develop and validate a cloud point extraction (CPE) method combined with spectrophotometry for the sensitive and environmentally friendly detection and quantification of QRC in pharmaceutical formulations and spiked urine samples. Methods. The CPE method employed Triton X-114 as a non-ionic surfactant to extract QRC from samples. The extraction process was optimized by evaluat
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Soesanto, Loekas Loekas Soesanto, Alvin Adhyatputera Ramadhana, Endang Mugiastuti, and Abdul Manan. "Effect of Four Liquid Organic Wastes on The Growth of Four Trichoderma harzianum Isolates and Their Effect on Cucumber Growth and Yield." SINTA Journal (Science, Technology, and Agricultural) 2, no. 2 (2022): 19–30. http://dx.doi.org/10.37638/sinta.2.2.19-30.

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The aim of this research was to determine the effect of fourliquid organic substrates on the growth of four Trichoderma harzianum isolates and their effect on cucumber growth and yield. Randomized block design was used with 20 treatments and 3 replicates. The treatments consisted of control, tofu liquid waste, rice washing water, coconut water, and tapioca waste substrates each combined with four T. harzianum isolates. Variables observed were conidia density during decomposition, conidia late density, crop height, root length, root fresh and dry weight, crop fresh and dry weight, the first flo
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Tarek, Mohamed, Hebatallah A. Wagdy, Eman S. Elzanfaly, and Sawsan M. Amer. "A Validated Ultra-Performance Liquid Chromatographic Method for the Simultaneous Determination of Nadifloxacin, Mometasone Furoate and Miconazole Nitrate in Their Combined Dosage Form and Spiked Human Plasma Samples." Journal of Chromatographic Science 57, no. 10 (2019): 867–73. http://dx.doi.org/10.1093/chromsci/bmz082.

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Abstract Nadifloxacin, mometasone furoate and miconazole nitrate are formulated together as a topical antifungal dosage form. In this work, a reversed-phase ultra-performance liquid chromatographic method coupled with a diode array detector (RP-UPLC-DAD) was developed and validated to determine nadifloxacin, mometasone furoate and miconazole nitrate simultaneously in their bulk powder, in pharmaceutical preparation and in spiked human plasma samples. Separation was achieved on an ACQUITY UPLC C18 column of 2.2 μm particle size (2.1 × 100 mm) via isocratic elution using a mobile phase consistin
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Pradnya, Lahupanchang* Shubham Tikait Dr. Swati Deshmukh. "Awareness Of Pharmaceutical Waste Management by Drug Reclamation Program." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 2633–44. https://doi.org/10.5281/zenodo.15431403.

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Wastes are the unwanted or unusable materials that people will no longer use for, which are either intended to get rid of or have already been discarded. Moreover, wastes can be hazardous to human or the environment as such, which has to be discarded immediately, else may cause serious health related problems in human. Biomedical waste means any solid or liquid waste which is generated during the diagnosis, treatment or immunization of human beings or animals. Thus pharmaceutical waste are manage by the various treatment processes and also aware to manage the pharmaceutical waste by the drugs
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Vishwanatth, Prof Dr Kannan. "AUTOMATED FLOW INJECTION SPECTROPHOTOMETRIC DETERMINATION OF THE PROTON PUMP INHIBITOR OMEPRAZOLE IN PHARMACEUTICAL FORMULATIONS." International Journal of Engineering Applied Sciences and Technology 7, no. 3 (2022): 63–68. http://dx.doi.org/10.33564/ijeast.2022.v07i03.009.

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A simple and fast flow-injection method for the determination of omeprazole in pharmaceutical preparations is proposed. Detection of the drug is based on the measurement of the absorption signals for the product resulting from the oxidation of omeprazole with N-bromosuccinimide in acidic medium. A flow rate of 0.5 ml/min was pumped and active material was detected at 370 nm. Limit of detection (LOD) and limit of quantitation (LOQ) were calculated to be 2.0 and 6.5 μg/ml, respectively. No interference was observed from common pharmaceutical additives. The method was successfully applied to the
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Dissertations / Theses on the topic "Spiked Pharmaceutical Liquid Waste"

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Nordström, Peter. "Minimizing Liquid Waste in Peptide Synthesis : A New Application for the Rotating Bed Reactor." Thesis, Umeå universitet, Institutionen för fysik, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-184016.

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Peptide drugs are used to treat a broad spectrum of diseases such as cancer and HIV and have many more promising applications, such as new vaccines against SARS-CoV-2. The most popular manufacturing method for peptides is solid-phase peptide synthesis (SPPS). The main drawback of SPPS is that it is a costly and wasteful process.  SpinChem is a company that provides technology solutions for chemical processes. Recently, SpinChem has started investigating if their Rotating Bed Reactor (RBR) is suitable for peptide synthesis. The goal of this project is to investigate how the RBR can make process
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Vašíčková, Petra. "Stanovení reziduí léčiv pomocí separačních metod." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2010. http://www.nusl.cz/ntk/nusl-216632.

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Nonsteroidal anti-inflammatory substances became a very frequently used and constantly evolved group of the drugs, particularly in a human medicine. The risk of their penetration into the environment, especially to the water environment, is rising during the recent years. The diploma thesis is focused on a selection of appropriate separation method and optimization of analytical procedure for the identification and determination of the non-steroidal anti-inflammatory drugs in sewage and surface waters. Salicylic acid, ketoprofen, diclofenac and ibuprofen were chosen from the wide range of NSAI
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Book chapters on the topic "Spiked Pharmaceutical Liquid Waste"

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Khalidi Idrissi, Amina, Abdelaziz Madinzi, Latifa Mouhir, et al. "Treatment of Liquid Waste Loaded with Pharmaceutical Products: A Case of Antibiotics." In Earth and Environmental Sciences Library. Springer Nature Switzerland, 2024. http://dx.doi.org/10.1007/978-3-031-74515-7_10.

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Anom, I. Dewe K., Marianus, J. Z. Lombok, and Lalu Rudyat Telly Savalas. "Kinetics of Gas and Liquid Smoke from Catalytic Pyrolysis of Human Hair Cut Waste and Its Characterization." In Atlantis Highlights in Chemistry and Pharmaceutical Sciences. Atlantis Press International BV, 2023. http://dx.doi.org/10.2991/978-94-6463-130-2_8.

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Patel, Shefali, Susmita Sahoo, Vinay Kumar, Sivarama Krishna Lakkaboyana, and Ritu Pasrija. "Use of Date Palm Fruit Processing Wastes to Produce High-Value Products." In Waste Valorization for Value-added Products. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815123074123010009.

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Fruits of the date have found great value in human nutrition because of their rich content of essential nutrients. Tons of palm fruit waste are being discarded daily. Waste such as date holes represents 10% of date fruit. Within the framework of the bio-economy, there is a high potential for date waste use in ligne-cellulosic products in a broad spectrum of bio-industries. Extensive and varied biomolecules may capture energy for use in the pharmaceutical industry as an active pharmaceutical ingredient (API), or in the development of nutraceuticals without using them as substrates for mass prod
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Nakov, Natalija, Jelena Acevska, Katerina Brezovska, Zoran Kavrakovski, and Aneta Dimitrovska. "Green Strategies toward Eco-Friendly HPLC Methods in Pharma Analysis." In High Performance Liquid Chromatography - Recent Advances and Applications [Working Title]. IntechOpen, 2023. http://dx.doi.org/10.5772/intechopen.110035.

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The global need for changing the processes in order to meet the green analytical chemistry (GAC) criteria is a great challenge for the pharmaceutical industry. High-performance liquid chromatography (HPLC), as one of the most frequently used techniques in various stages in the pharmaceutical industry, generates huge amounts of organic toxic waste. Therefore, the implementation of the GAC principles in pharma analysis is highly required. Although the number of published papers concerning green chromatography approaches is constantly increasing, the use of eco-friendly HPLC methods in the pharma
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Rajasekhar, K., Ch Gangu Naidu, Ch Naga Sesha Sai Pavan Kumar, K. Varaprasada Rao, and Y. Srinivasa Rao. "Development and Validation of A RP-HPLC Method for the Simultaneous Determination of Twenty Related Substances of Sulfamethoxazole and Trimethoprim in Injection Dosage Form." In Current Trends in Drug Discovery, Development and Delivery (CTD4-2022). Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671090-00246.

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A simple, robust and for the quantification of experimentally 20 related impurities of sulfamethoxazole (SM) and trimethoprim (TM) in liquid pharmaceutical dosage form, a novel RP-HPLC method was developed. Utilizing gradient elution on a Kromasil 100-5-C18; 5.0 m, (4.0x250) mm, column, chromatographic separation was accomplished. Solvent A (solution of 0.08% orthophosphoric acid in water) and Solvent B (mixture of acetonitrile and methanol, 80:20 v/v), given at a flow rate of 0.8 ml/min, respectively, make up the mobile phase. Using a photodiode array (PDA) detector, the analytes were identif
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el Farissi, Hammadi. "Valorization of Forest Waste for the Production of Dio-oils for Biofuel and Biodiesel." In Advances in Green Electronics Technologies [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.105366.

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Biomass is a renewable energy source to generate heat and electricity through the enhancement of various organic materials. Cistus slow pyrolysis of seeds and shells was carried out in a fixed bed reactor to determine the effect of pyrolysis temperature, heating rate, and particle size on the performance of pyrolysis. Therefore, pyrolysis experiments were performed at different temperatures, ranging from 300 to 500°C, with heating rates varying from 10 to 70°C.min−1 for shells and 7 to 28°C.min−1 for seeds. The particle sizes of samples range from 0.3 to 3.5 mm for shells and 0.075 to 1.2 mm f
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Green, Lesley, and Vanessa Farr. "The False Bay Coast of Cape Town: A Critical Zone." In Ecological Reparation. Policy Press, 2023. http://dx.doi.org/10.1332/policypress/9781529239546.003.0004.

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Focusing on the southern regions of Cape Town, South Africa, we focus on the landscape around our city’s major waste dump, Capricorn, named for the Sea Goat of astrologers, that is alongside shack settlements, ganglands, a businesspark, a nature reserve and a sewage works. Using images from Google Earth we show how Cape Town’s policies for water and waste management are designed for solid, liquid, and gas, yet the chemical and pharmaceutical industries of our time leach, flow, aggregate, metabolize, sediment and bioaccumulate in bodies and soils, from the dump site and the sewage plant.Invento
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Lúcia Cavalcanti de Amorim, Elba, Patrícia Cruz, Jorge Veras Filho, et al. "Brazilian Caatinga: Phenolic Contents, Industrial and Therapeutic Applications." In Phenolic Compounds [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.99223.

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Phenolic compounds, mainly represented by flavonoids, tannins and coumarins, bioactive molecules with various applications, have antioxidant, photoprotective, antimicrobial, anti-inflammatory and even antitumor properties. The main mechanism of action of phenolic compounds is due to the transfer of electrons to free radicals, which leads to the interruption of oxidative reactions. The flora of the Brazilian caatinga is full of species with high concentrations of these compounds, which are possibilities for researching new pharmaceutical products and functional foods, and may even generate tech
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Conference papers on the topic "Spiked Pharmaceutical Liquid Waste"

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Hartono, Victor Trimanjaya Hulu, Frans Judea Samosir, et al. "The Effectiveness of Activated Carbon and PAC in Reducing Phosphate Levels in Laundry Liquid Waste." In International Conference on Health Informatics, Medical, Biological Engineering, and Pharmaceutical. SCITEPRESS - Science and Technology Publications, 2020. http://dx.doi.org/10.5220/0010292201740180.

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Hafez, Nancey. "PURIFICATION OF PHARMACEUTICAL WASTE WATER RESULTING FROM HERBAL PLANTS BY ZERO LIQUID DISCHARGE TECHNIQUES (ZLD)." In International Trends in Science and Technology. RS Global Sp. z O.O., 2021. http://dx.doi.org/10.31435/rsglobal_conf/30052021/7582.

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Petrenko, O. A., O. V. Samylova, A. A. Kuznetsova, Yu V. Shcherbakova, and F. Y. Akhmadullina. "THE USE OF WASTE FROM PHARMACEUTICAL PRODUCTION FOR THE CREATION OF BIOTECHNOLOGICAL PRODUCTS." In X Международная конференция молодых ученых: биоинформатиков, биотехнологов, биофизиков, вирусологов и молекулярных биологов — 2023. Novosibirsk State University, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-113.

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The state of the environment, excessive consumption of synthetic medicines, food additives and preservatives have a significant impact on the biological production of free radicals underlying a number of diseases and pathological conditions, such as atherosclerosis, coronary heart disease, oncological diseases and others. To correct these conditions and for preventive purposes, vegetable raw materials containing a large set of antioxidants are increasingly used: vitamins, flavonoids and tannins with a mild effect on the body and relatively low toxicity. However, even after the production of su
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Sheng, Chenguang, A. G. Agwu Nnanna, Yanghe Liu, and John D. Vargo. "Removal of Pharmaceutical Contaminants in Water." In ASME 2015 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/imece2015-53240.

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Pharmaceutical contaminants in drinking water could potentially lead to increasing risks of heart attacks, organ damage, mental health and even cancer. Because their presence, frequency of occurrence, or source may not be known, the chemicals being discovered in water that previously had not been detected or are being detected at levels that may be significantly different than expected. Removal of emerging contaminants is considered recently to be one of the most important processes within advanced Waste Water Treatment Plants (WWTPs) system. EPA is working to improve its understanding of a nu
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AlOudah, Yahya. "Waste Management Control by Applying Novel Method for HPLC Technique to Replace SKALAR Cadmium Reduction Method for Nitrate and Nitrite in Water Analysis." In International Petroleum Technology Conference. IPTC, 2022. http://dx.doi.org/10.2523/iptc-22291-ea.

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Abstract A new method was developed on High Performance Liquid Chromatography (HPLC) instrument equipped with a Photodiode Array UV detector to determine the Nitrite-Nitrogen and Nitrate-Nitrogen in seawater, industrial wastewater, and groundwater at very low concentrations. This HPLC used a reverse phase system with polar mobile phase and nonpolar C-18 Column. The split mechanism of the HPLC Chromatography was accomplished by employing acetonitrile and acidified water with pH 2.5, at 55:45 ACN: H2O v/v as a mobile phase, long HPLC Column (C-18, 0.5 μm, 250 × 4.6 mm) and at 1 mL/min flow rate.
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Sokolović, Dunja. "APPLICATION OF COALESCENCE FILTRATION IN SUSTAINABLE ENVIRONMENTAL PRACTICE." In INTERNATIONAL Conference on Business, Management, and Economics Engineering Future-BME. Faculty of Technical Sciences, Novi Sad, 2025. https://doi.org/10.24867/future-bme-2024-128.

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This paper presents how coalescence filtration could be applied in sustainable environmental practice. The coalescence filtration is a separation method that could be used in a wide range of industries (petrochemical, chemical, food, pharmaceutical, power plants, etc.) mostly for the separation of liquid/liquid and gas/liquid dispersed systems, like oily wastewater and metalworking fluid (MWF) aerosols. Filter media in coalescence filtration could be varied from different polymers up to stainless steel. It is very important to point out that the latest literature review shows that waste polyme
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Adams, Jonathan F. W., Simon R. Biggs, Michael Fairweather, Jun Yao, and James Young. "Transport of Nuclear Waste Flows: A Modelling and Simulation Approach." In ASME 2011 14th International Conference on Environmental Remediation and Radioactive Waste Management. ASMEDC, 2011. http://dx.doi.org/10.1115/icem2011-59136.

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The task of implementing safer and more efficient processing and transport techniques in the handling of nuclear wastes made up of liquid-solid mixtures provides a challenging and interesting area of research. The radioactive nature of nuclear waste means that it is difficult to perform experimental studies of its transport. In contrast, the use of modelling and simulation techniques can help to elucidate the physics that underpin such flows and provide valuable insights into common problems associated with their transport, as well as assisting in the focusing of experimental research. Two pha
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Chizzola, Remigius, Harinder Makkar, Ellen McGrath, and Papu Haroon. "EXTRACTION OF ANTIOXIDANTS FROM MORINGA OLEIFERA LEAVES, STABILITY OF THE RESULTING ANTIOXIDANTS, AND USE OF THE REMAINING RESIDUE AS LIVESTOCK FEED." In 23rd SGEM International Multidisciplinary Scientific GeoConference 2023. STEF92 Technology, 2023. http://dx.doi.org/10.5593/sgem2023v/6.2/s25.27.

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Moringa oleifera, commonly known as horse radish tree or drumstick tree is a perennial multipurpose tropical tree. It can be used as medicine, cosmetic and functional food, among others. The benefits of using the leaves are ascribed to the presence of a number of antioxidants. Nowadays it is widely cultivated and naturalized in many countries. Simple methods to extract antioxidants from Moringa leaf are lacking, which were established, stability of antioxidants was assessed, and residue left after extraction was explored for use as animal feed, with the aim to scale-up the process to industria
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