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Journal articles on the topic 'Spinal computational-surgery'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Sciortino, Vincenza, Salvatore Pasta, Tommaso Ingrassia, and Donatella Cerniglia. "On the Finite Element Modeling of the Lumbar Spine: A Schematic Review." Applied Sciences 13, no. 2 (2023): 958. http://dx.doi.org/10.3390/app13020958.

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Finite element modelling of the lumbar spine is a challenging problem. Lower back pain is among the most common pathologies in the global populations, owing to which the patient may need to undergo surgery. The latter may differ in nature and complexity because of spinal disease and patient contraindications (i.e., aging). Today, the understanding of spinal column biomechanics may lead to better comprehension of the disease progression as well as to the development of innovative therapeutic strategies. Better insight into the spine’s biomechanics would certainly guarantee an evolution of curre

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Sigurdarson, Hafthor, Aditya Joshi, Aria Mohebi, and Hamid Hassanzadeh. "Applications and quality assurance of artificial intelligence in adult spinal deformity surgery." Artificial Intelligence Surgery 5, no. 2 (2025): 283–97. https://doi.org/10.20517/ais.2024.35.

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Artificial intelligence (AI) is reshaping healthcare, particularly within the realm of spinal surgery, enhancing diagnostics, treatment, and patient management. AI is not only enhancing the technical aspects of spinal surgery but also revolutionizing patient care through personalized management, setting a new standard within the field. This computational renaissance has received increasing attention from providers and regulatory bodies to ensure novel technologies are being safely and effectively used. This review explores contemporary uses of AI in adult spinal deformity (ASD) surgery and the

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Gatton, Michelle L., Mark J. Pearcy, and Graeme J. Pettet. "Computational model of the lumbar spine musculature: Implications of spinal surgery." Clinical Biomechanics 26, no. 2 (2011): 116–22. http://dx.doi.org/10.1016/j.clinbiomech.2010.09.017.

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Leblond, Lugdivine, Patrice Sudres, and Morgane Evin. "Cerebro-spinal flow pattern in the cervical subarachnoid space of healthy volunteers: Influence of the spinal cord morphology." PLOS ONE 19, no. 8 (2024): e0290927. http://dx.doi.org/10.1371/journal.pone.0290927.

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Introduction Toward further cerebro-spinal flow quantification in clinical practice, this study aims at assessing the variations in the cerebro spinal fluid flow pattern associated with change in the morphology of the subarachnoid space of the cervical canal of healthy humans by developing a computational fluid dynamics model. Methods 3D T2-space MRI sequence images of the cervical spine were used to segment 11 cervical subarachnoid space. Model validation (time-step, mesh size, size and number of boundary layers, influences of parted inflow and inflow continuous velocity) was performed a 40-y

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de Almeida, Romulo Augusto Andrade, Daniel Ledbetter, Xizi Wu, et al. "Abstract 3339: TTFields for the management of spinal metastases in in vitro and in vivo models." Cancer Research 84, no. 6_Supplement (2024): 3339. http://dx.doi.org/10.1158/1538-7445.am2024-3339.

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Abstract Spine metastases often affect cancer patients, leading to significant morbidity and mortality. Their prevalence has increased over time due to the progressive improvements in cancer management which led to a longer survival of these individuals. Radiation therapy is the mainstay treatment for local control of these lesions, with surgery reserved for selected cases (e.g., spinal instability, neurological deficits secondary to neural compression requiring urgent decompression, separation surgery). Chemotherapy addresses the diffusely metastatic spread. However, when spinal metastases pr

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Lollis, S. Scott, Xiaoyao Fan, Linton Evans, et al. "Use of Stereovision for Intraoperative Coregistration of a Spinal Surgical Field: A Human Feasibility Study." Operative Neurosurgery 14, no. 1 (2017): 29–35. http://dx.doi.org/10.1093/ons/opx132.

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AbstractBACKGROUNDThe use of image guidance during spinal surgery has been limited by several anatomic factors such as intervertebral segment motion and ineffective spine immobilization. In its current form, the surgical field is coregistered with a preoperative computed tomography (CT), often obtained in a different spinal confirmation, or with intraoperative cross-sectional imaging. Stereovision offers an alternative method of registration.OBJECTIVETo demonstrate the feasibility of stereovision-mediated coregistration of a human spinal surgical field using a proof-of-principle study, and to

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Linge, Svein O., Kent-A. Mardal, Anders Helgeland, John D. Heiss, and Victor Haughton. "Effect of craniovertebral decompression on CSF dynamics in Chiari malformation Type I studied with computational fluid dynamics." Journal of Neurosurgery: Spine 21, no. 4 (2014): 559–64. http://dx.doi.org/10.3171/2014.6.spine13950.

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Object The effect of craniovertebral decompression surgery on CSF flow dynamics in patients with Chiari malformation Type I (CM-I) has been incompletely characterized. The authors used computational fluid dynamics to calculate the effect of decompression surgery on CSF flow dynamics in the posterior fossa and upper cervical spinal canal. Methods Oscillatory flow was simulated in idealized 3D models of the normal adult and the CM-I subarachnoid spaces (both previously described) and in 3 models of CM-I post–craniovertebral decompressions. The 3 postoperative models were created from the CM mode

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Joshi, Rushikesh S., Darryl Lau, Justin K. Scheer, et al. "State-of-the-art reviews predictive modeling in adult spinal deformity: applications of advanced analytics." Spine Deformity 9, no. 5 (2021): 1223–39. http://dx.doi.org/10.1007/s43390-021-00360-0.

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AbstractAdult spinal deformity (ASD) is a complex and heterogeneous disease that can severely impact patients’ lives. While it is clear that surgical correction can achieve significant improvement of spinopelvic parameters and quality of life measures in adults with spinal deformity, there remains a high risk of complication associated with surgical approaches to adult deformity. Over the past decade, utilization of surgical correction for ASD has increased dramatically as deformity correction techniques have become more refined and widely adopted. Along with this increase in surgical utilizat

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Le, Minh-Thai, Ching-Chi Hsu, and Kao-Shang Shih. "EVALUATION OF VARIOUS DEVICE DESIGNS FOR POSTERIOR LUMBAR INTERBODY FUSION SURGERY USING A T10–S1 MULTILEVEL SPINE MODEL." Biomedical Engineering: Applications, Basis and Communications 30, no. 01 (2018): 1850003. http://dx.doi.org/10.4015/s1016237218500035.

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A spinal fusion surgery has been the gold standard treatment for treating lumbar degenerative disc disease. Many clinical studies have demonstrated that adjacent segment degeneration was observed in patients over time. Different types of stabilization systems have been investigated using numerical approaches. However, numerical models developed in the past were simplified to reduce computational time. Additionally, it is quite difficult to compare different stabilization systems in clinical application due to variation in bone anatomy and density. The aim of this study is to evaluate and compa

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Tatsui, Claudio E., Kristen W. Carlson, and Chirag B. Patel. "Abstract 2396: Tumor treating fields (TTFields) for spinal metastasis: Clinical trial concept for use of conductive implants as waveguides to enhance TTFields strength." Cancer Research 84, no. 6_Supplement (2024): 2396. http://dx.doi.org/10.1158/1538-7445.am2024-2396.

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Abstract Tumor treating fields (TTFields) is a FDA-approved electric fields-based therapy for glioblastoma (GBM) and malignant pleural mesothelioma. We describe a novel approach to increase the strength and therapeutic effect of TTFields at vertebral tumor targets, using spinal implants as electrically-conductive waveguides. In vivo anti-cancer efficacy is achieved with TTFields strength &gt;1 V/cm. If the tumor is surrounded by tissues of lower conductivity (e.g., the skull in the case of GBM), then the TTFields strength reaching the tumor is decreased. Surgical treatment of radiation-ref

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Rogozinskyi, V. O., A. F. Levytskyi, M. M. Dolianytskyi та O. V. Yaresko. "Analysis of mathematical modeling of a biomechanical model of halo-graviеn traction in spinal deformities in children". Paediatric Surgery. Ukraine, № 4(73) (30 грудня 2021): 66–71. http://dx.doi.org/10.15574/ps.2021.73.66.

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Halo-gravity traction (HGT) systems are widely used in leading clinics around the world as a staged method for correcting complex (>100°) scoliotic deformities of the spine in children. Today there is no single approach to the use of this technique, and each doctor makes a decision regarding the treatment regimen empirically, based on his clinical experience. Purpose – to investigate with the help of finite element method the stress-strain state of the spine of various degrees of deformation using HGT. Materials and methods. When constructing the computational model, geometric models of var

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Hu, Lei, Yonghong Zhang, Jian Zhang, et al. "STP-Net: A Signal Prediction Method of Laminar Decompression Robot Based on Swin Transformer." International Journal of Intelligent Systems 2023 (April 12, 2023): 1–20. http://dx.doi.org/10.1155/2023/7842495.

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Spinal surgery robots have a great application value in laminar decompression surgery. For a safe surgery, the robot needs to accurately identify the cutting state of the lamina. Therefore, it is very important to deal with various sensing signals in the form of a time series. However, various state recognition algorithms proposed so far cannot completely avoid cutting through the lamina, leaving hidden dangers for nerve thermal damage caused by high-temperature liquid splashing. We propose a long time series prediction algorithm called STP-Net, which combined with the existing algorithms for

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Francisco, Casesnoves. "Computational-Reumathological Cad Clinical Diagnosis with Lumbar Vertebral Cadaveric Specimens and Spine Sub-Units Mathematical Modeling. Part III." International Journal of Mathematics and Computer Research 13, no. 05 (2025): 5193–204. https://doi.org/10.5281/zenodo.15423970.

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Continuing this biomechanical research line, and based on previous series, a subsequent reumathologically-directed clinical study with 3D-CAD imaging-processing was done. In this part with GNU Octave and Matlab programming—comparing both. The lumbar cadaveric specimen is a different one related to previous publications specimens of bioengineering laboratory. The objective of the research is the clinical finding of lumbar spine degeneration signs, arthrosis, osteoarthritis, deformations, and disk herniations. The software method is presented in series of 3D-CAD lumbar vertebral imaging pr

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Patel, Ruchit V., Alexander G. Yearley, Hannah Isaac, Eric J. Chalif, Joshua I. Chalif, and Hasan A. Zaidi. "Advances and Evolving Challenges in Spinal Deformity Surgery." Journal of Clinical Medicine 12, no. 19 (2023): 6386. http://dx.doi.org/10.3390/jcm12196386.

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Background: Surgical intervention is a critical tool to address adult spinal deformity (ASD). Given the evolution of spinal surgical techniques, we sought to characterize developments in ASD correction and barriers impacting clinical outcomes. Methods: We conducted a literature review utilizing PubMed, Embase, Web of Science, and Google Scholar to examine advances in ASD surgical correction and ongoing challenges from patient and clinician perspectives. ASD procedures were examined across pre-, intra-, and post-operative phases. Results: Several factors influence the effectiveness of ASD corre

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Bilston, Lynne E., Marcus A. Stoodley, and David F. Fletcher. "The influence of the relative timing of arterial and subarachnoid space pulse waves on spinal perivascular cerebrospinal fluid flow as a possible factor in syrinx development." Journal of Neurosurgery 112, no. 4 (2010): 808–13. http://dx.doi.org/10.3171/2009.5.jns08945.

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Object The mechanisms of syringomyelia have long puzzled neurosurgeons and researchers alike due to difficulties in identifying the driving forces behind fluid flow into a syrinx, apparently against a pressure gradient between the spinal cord and the subarachnoid space (SAS). Recently, the synchronization between CSF flow and the cardiac cycle has been postulated to affect fluid flow in the spinal cord. This study aims to determine the effect of changes in the timing of SAS pressure on perivascular flow into the spinal cord. Methods This study uses a computational fluid dynamics model to inves

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Martinez, Casey, Camryn Payne, Jonathan L. Jeger, et al. "Spino-plastic surgery, back to the future." Artificial Intelligence Surgery 5, no. 1 (2025): 16–23. https://doi.org/10.20517/ais.2024.73.

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Artificial intelligence (AI) is a powerful computational tool that is being utilized more frequently in healthcare. AI holds promise within surgical practice, including application in the care of challenging patient populations. Complex spine reconstruction requires thorough multi-variable preoperative analysis and then the precise enactment of a surgical plan. Spino-plastics employs vascularized bone grafts (VBGs) to augment spinal fusion in these high-risk patients. In this article, we discuss the great breadth of AI and the tremendous potential for advancing the field of spino-plastics: sur

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Liang, Liang, Bai Chen, Yong Tang, Yan Xu, and Yu Liu. "Operational performance analysis of spiral capsule robot in multiphase fluid." Robotica 37, no. 2 (2018): 213–32. http://dx.doi.org/10.1017/s0263574718000954.

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SUMMARYMinimally invasive surgery is a developing direction of modern medicine. With the successful development of controllable capsule endoscopies, capsule robots are very popular in the field of gastrointestinal medicine. At present, the study of intestinal robots is aimed at the pipeline environment of a single-phase liquid flow. But there exist food residues (i.e. solid particles) or liquid foods in the actual intestine, so intestinal fluid should be liquid–solid or liquid–liquid two-phase mixed fluid. For inner spiral capsule robots with different internal diameters and outer spiral capsu

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Ivanov, D. V., L. V. Bessonov, I. V. Kirillova, L. Yu Kossovich, and S. I. Kireev. "The concept of medical decision support systems in surgery of the spinal pelvic complex." Izvestiya of Saratov University. Mathematics. Mechanics. Informatics 22, no. 4 (2022): 517–35. http://dx.doi.org/10.18500/1816-9791-2022-22-4-517-535.

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Faheem, Muhammad, Syed Hussain Ali, Abdul Waheed Khan, et al. "1,3,4-Oxadiazole Derivative Attenuates Chronic Constriction Injury Induced Neuropathic Pain: A Computational, Behavioral, and Molecular Approach." Brain Sciences 10, no. 10 (2020): 731. http://dx.doi.org/10.3390/brainsci10100731.

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The production and up-regulation of inflammatory mediators are contributing factors for the development and maintenance of neuropathic pain. In the present study, the post-treatment of synthetic 1,3,4 oxadiazole derivative (B3) for its neuroprotective potential in chronic constriction injury-induced neuropathic pain was applied. In-silico studies were carried out through Auto Dock, PyRx, and DSV to obtain the possible binding and interactions of the ligands (B3) with COX-2, IL-6, and iNOS. The sciatic nerve of the anesthetized rat was constricted with sutures 3/0. Treatment with 1,3,4-oxadiazo

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Mahajan, Neetin, Sunny Sangma, Jayesh Mhatre, and Pritam Talukder. "Case Series of the Management of Surgical Site Infection following Thoracic Spinal Surgeries during COVID Pandemic." Back Bone Journal 3, no. 1 (2022): 24–31. http://dx.doi.org/10.13107/bbj.2022.v03i01.036.

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Introduction: Post-operative spinal wound infection increases the morbidity of the patient and the cost of healthcare. Despite the development of prophylactic antibiotics and advances in surgical technique and post-operative care, wound infection continues to compromise patient outcome after spinal surgery. This kind of infection places the patient at risk for pseudoarthrosis, adverse neurologic sequelae, chronic pain, deformity, and even death. In spite of all preventive measures, the SSI following spinal surgeries are 1% among operated spinal instrumentation. Case Series: Here, we present a

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Dave, Bharat, Ajay Krishnan, Devanand Degulmadi, Shivanand Mayi, Ravi Ranjan Rai, and Vatsal N. Parmar. "A Case of C 3 Aneurysmal Bone Cyst Managed by Staged Surgery." Back Bone Journal 2, no. 2 (2021): 89–92. http://dx.doi.org/10.13107/bbj.2022.v02i02.027.

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Aneurysmal bone cysts are often mistaken as malignant tumors such as lesions or another benign bony lesion because of their proliferative component. Treatment of spinal aneurysmal bone cyst is challenging because of its proximity to the spinal cord, unique pathology, and complex growth characteristics. The treatment options are curettage and bone grafting, irradiation, embolization, intralesional injection of calcitonin, and steroid. We present a case of cervical aneurysmal bone cysts operated in a staged procedure: arterial embolization followed by surgical resection and stabilization. Keywor

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Alshareef, Mohammed, Ahmed Alshareef, Tyler Vasas, Aakash Shingala, Jonathan Cutrone, and Ramin Eskandari. "Pediatric Cranioplasty Using Hydroxyapatite Cement: A Retrospective Review and Preliminary Computational Model." Pediatric Neurosurgery 57, no. 1 (2021): 40–49. http://dx.doi.org/10.1159/000520954.

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Introduction: Cranioplasty is a standard technique for skull defect repair. Restoration of cranial defects is imperative for brain protection and allowing for homeostasis of cerebral spinal fluid within the cranial vault. Calcium phosphate hydroxyapatite (HA) is a synthetic-organic material that is commonly used in cranioplasty. We evaluate a patient series undergoing HA cement cranioplasty with underlying bioresorbable mesh for various cranial defects and propose a preliminary computational model for understanding skull osteointegration. Methods: A retrospective review was performed at the in

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Patel, Tarak N. "Transforaminal Lumbar Interbody Fusion in Multilevel Lytic Listhesis – A Rare Case Report." Back Bone Journal 2, no. 2 (2021): 102–4. http://dx.doi.org/10.13107/bbj.2022.v02i02.030.

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Spondylolisthesis is a spinal condition that affects the lower vertebrae (spinal bones). This disease causes one of the lower vertebrae to slip forward onto the bone directly beneath it. It is a painful condition but treatable in most cases. We have described an unusual case of multilevel lytic spondylolisthesis in a patient presenting with back pain and neurogenic claudication. The patient underwent an uneventful post-operative recovery. At a recent follow-up, 3 months after the surgery, the symptoms of the patient were significantly improved. The patient was ambulating without aid and did no

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Teixeira, Manoel Jacobsen, Fabrício Freitas de Almeida, Ywzhe Sifuentes Almeida de Oliveira, and Erich Talamoni Fonoff. "Microendoscopic stereotactic-guided percutaneous radiofrequency trigeminal nucleotractotomy." Journal of Neurosurgery 116, no. 2 (2012): 331–35. http://dx.doi.org/10.3171/2011.8.jns11618.

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Object Over the past few decades, various authors have performed open or stereotactic trigeminal nucleotractotomy for the treatment of neuropathic facial pain resistant to medical treatment. Stereotactic procedures can be performed percutaneously under local anesthesia, allowing intraoperative neurological examination as a method for target refinement. However, blind percutaneous procedures in the region of the atlantooccipital transition carry a considerably high risk of vascular injuries that may bring prohibitive neurological deficit or even death. To avoid such complications, the authors p

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Park, Jong-Beom. "Paradigm Shift of Interspinous Device Surgery for Degenerative Lumbar Diseases." Back Bone Journal 3, no. 1 (2022): 4–6. http://dx.doi.org/10.13107/bbj.2022.v03i01.032.

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Instrumented fusion surgery is an effective surgery for severe degenerative lumbar diseases and can achieve satisfactory clinical outcomes with a high fusion rate. However, due to extensive nature and loss of segmental motion, instrumented fusion can cause complications and adjacent segment disease, and some patients require second surgery. On the contrary, decompression alone is an effective surgery for moderate degenerative lumbar diseases and can achieve satisfactory clinical outcomes. However, failed back surgery syndrome, such as recurrent lumbar disc herniation or spinal stenosis, can oc

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Patel, Ravish, Shivam Shah, Naresh Kumar, and Shammi Patel. "Periosteal Variety of Sacral Osteoid Osteoma Encroaching into the Spinal Canal – Treatment with a Tubular Retractor System: Case Report." Back Bone Journal 2, no. 2 (2021): 89–92. http://dx.doi.org/10.13107/bbj.2022.v02i02.028.

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Background: Osteoid osteomas are benign primary bone tumors with a predilection for posterior elements of the spinal column. Complete surgical excision through a traditional open approach is the treatment of choice for patients not responding to non-steroidal anti-inflammatory medications and patients with contraindications for nidus ablation. The study aims to highlight an alternative minimally invasive technique for complete surgical excision of osteoid osteoma encroaching into the spinal canal. Methods: We report a case of 22 years-old obese male suffering from left S1 radiculopathy and nig

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Krishnan, Ajay, Devanand Degulmadi, Ravi Ranjan, et al. "Hemodynamic Neuromonitoring, a Proposed Spino-Cardiac Protective Reflex: Prospective Study in 200 Patients of Lumbar Surgery." Back Bone Journal 2, no. 2 (2021): 71–78. http://dx.doi.org/10.13107/bbj.2022.v02i02.024.

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Background: Parasympathomimetic reflexes are reported in literature in spine surgery. Our primary hypothesis is proposed that nociceptive stimuli can be elicited by various maneuvers of lumbar spinal surgery and the physiological manifestation depends on many patient variables and anesthesia. However, a sympathomimetic pathological response is indicative of potential neural damages, which may or may not be reversible. A spino-cardiac protective reflex (SPR), as a new entity for lumbar spinal surgery, is proposed. Study Design: This was a prospective single institution. Materials and Methods: A

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Zhang, Wenlu, Ziyue Ma, Hong Wang, et al. "Study on automatic ultrasound scanning of lumbar spine and visualization system for path planning in lumbar puncture surgery." Mathematical Biosciences and Engineering 20, no. 1 (2022): 613–23. http://dx.doi.org/10.3934/mbe.2023028.

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<abstract> <p>In lumbar puncture surgery, compared with the conventional methodologies like computed tomography and magnetic resonance imaging, ultrasound imaging offers the advantages of being low cost, no radiation and real-time image generation. However, the use of ultrasound equipment in lumbar puncture involves a cumbersome and time-consuming process for the subjective imaging of the overall structure of the lumbar spine in order to determine the exact puncture point and path. Meanwhile, the robotic arm puncture system has the advantages of high precision, good stability and s

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Krishnan, Ajay, Shivakumar A. Bali, Devanand Degulmadi, et al. "Presumptive Long Rod Technique (PLRT) for Revision Extension Instrumented Spine Surgery: A Technical Note." Back Bone Journal 3, no. 2 (2022): 119–24. http://dx.doi.org/10.13107/bbj.2022.v03i02.050.

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Background: Revision spine surgery needing extension of fixation either require complete exposure of previously operated levels for rod exchange or can be managed by linking the new surgical construct (NSC) to primary surgical construct (PSC) with dominos. Presumptive long rod technique (PLRT) provides additional length of rod for domino placement. Case report: 80-year male on conservative management developed acute cauda equina syndrome retention due to pre-existing multilevel lumbar stenosis and acute big sequestrated disc prolapse at L12. Emergent surgical intervention in form of L1 to L4 p

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Modi, Hitesh N., and Udit D. Patel. "Spontaneous Spinal Epidural Hematoma Causing Paraparesis in a Patient of Mitral Valve Replacement with Anticoagulant Treatment – A Decision Dilemma." Back Bone Journal 3, no. 1 (2022): 36–41. http://dx.doi.org/10.13107/bbj.2022.v03i01.038.

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Summary and Background: Spontaneous spinal epidural hematoma (SSEH) is a known occurrence in patients on anticoagulant therapy. There is an increased risk of developing hematoma after the spine surgery if anticoagulation therapy is reinstated. Purpose of Study: The purpose of the study was to find out solution related with perioperative anticoagulant therapy in high-risk cases if patient redevelops hematoma and paraplegia due to continuation of anticoagulant therapy. Case Report: A 30-year-old male presented to us with history of progressive paraparesis. He had history of mitral valve replacem

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Islam, Md Anowarul, Suvradev Saha, Md Mohoshin Sarker, and Afia Ibnat Islam. "Outcome of ACCF in Multilevel Cervical Spondylotic Myelopathy with OPLL and Kyphotic Deformity." Back Bone Journal 3, no. 2 (2022): 78–83. http://dx.doi.org/10.13107/bbj.2022.v03i02.044.

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Purpose: To evaluate the Outcome of Anterior cervical corpectomy & Fusion in multilevel Cervical Spondylotic Myelopathy with Ossification Posterior Longitudinal Ligament & kyphotic deformity. Background: Cervical spondylotic myelopathy (CSM) is the most common cause of spinal cord dysfunction in the adult. Ossification of the posterior longitudinal ligament (OPLL) is a hyperostotic condition of the spine, where the PLL becomes progressively calcified, leading to spinal canal stenosis. Anterior decompression by corpectomy and removal of ossified posterior longitudinal ligament is a well

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Modi, Hitesh N., Utsab Shrestha, and Udit D. Patel. "Clinical and Radiological Outcome of Minimally Invasive- Transforaminal Lumbar Interbody Fusion in Patients with Single or Double-Level Involvement with Minimum 2-Year Follow-up." Back Bone Journal 2, no. 2 (2021): 65–70. http://dx.doi.org/10.13107/bbj.2022.v02i02.023.

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Purpose: The objective of this study is to analyze the clinical and radiological outcome of Minimally Invasive-Transforaminal Lumbar Interbody Fusion (MIS-TLIF) in terms of estimated blood loss (EBL), operative time, length of stay (LOS) in the hospital, complication, Oswestry disability index (ODI) score, visual analog scale (VAS) score, and parameters of sagittal spinal balance before and after surgery. The parameters of sagittal spinal balance included in this study were pelvic Incidence (PI), lumbar lordosis, focal lordosis at the index level. Materials and Methods: All cases were retrospe

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Krishnan, Ajay, Preethesh Agrawal, Vatsal Parmar, et al. "Gorham Stout Disease- A Rare Disorder with Ambiguous Recommendations: A Systematic Review of literature." Back Bone Journal 3, no. 2 (2022): 65–67. http://dx.doi.org/10.13107/bbj.2022.v03i02.043.

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Background: Vanishing bone disease / Gorham-Stout disease (GSD) is a condition that produces deformity and instability of bone. The fibro lympho-vascular tissue replaces the bone leading to massive osteolysis and its sequelae, but the exact cause is yet unknown. The disease involves the spine infrequently, but due to the proximity of the spinal cord it can seriously affect the patient. The aim of this study is to report as a review to contribute to the diagnosis, and treatment modalities in GSD affection of spine with the reported literature available from 1983 till March 2022. Materials &

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Walker, Corey T., Robin Babadjouni, Wende Gibbs, et al. "Current Concepts on Imaging and Artificial Intelligence of Osteosarcopenia in the Aging Spine – A Review for Spinal Surgeons by the SRS Adult Spinal Deformity Task Force on Senescence." Spine, June 13, 2025. https://doi.org/10.1097/brs.0000000000005426.

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Study Design. Narrative review. Objective. To explore the intersection of osteoporosis, sarcopenia, radiomics, and machine learning in spine surgery, with a focus on clinical applications and opportunities for advancing assessment and predictive modeling methods. Summary of Background Data. Osteoporosis and sarcopenia are significant contributors to negative outcomes in the aging adult spine. Current methodologies for evaluating these disease states remain limited, with significant variability and poor standardization. Advances in computational medicine provide a novel opportunity to improve q

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Vinodhini, Francisco. "Software Programming with Lumbar Spine Cadaveric Specimens for Computational Biomedical Applications." International Journal of Scientific Research in Computer Science, Engineering and Information Technology, January 1, 2021, 07–15. http://dx.doi.org/10.32628/cseit206663.

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This contribution deals with demonstration of software-computational methods (CAD) to digitalize, simulate, and fit mathematically the anterior vertebral body morphometry of cadaveric lumbar spines. From previous research publications, computational techniques are developed and explained. Based on anatomical-cadaveric spinal specimens, experimental data was implemented to obtain practical surgical applications. With these anatomical samples, large sets of surface digital points were generated. Complete anterior vertebral body morphologies were visualized and analyzed with designed software-eng

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Ananth Swaminathan, Siddarth, Nima Taheri, Luis Becker, Matthias Pumberger, Hendrik Schmidt, and Sara Checa. "Impact of Habitual Flexion on Bone Formation After Spinal Fusion Surgery: An In Silico Study." JOR SPINE 8, no. 3 (2025). https://doi.org/10.1002/jsp2.70075.

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ABSTRACTBackgroundLumbar spinal fusion is currently regarded as one of the most effective surgical treatments for patients with spinal deformities, degenerative disc disease, and degenerative spondylolisthesis. However, the procedure still faces a high incidence of non‐unions. A key factor contributing to non‐union is stress shielding effects related to unfavorable mechanical signals at the fusion site. Mechanical conditions at the fusion site are determined by the loading conditions that result from daily activities. Recent studies have reported that humans spend most of the day with their sp

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Fasser, Marie-Rosa, Gabriela Gerber, Caroline Passaplan, et al. "Computational model predicts risk of spinal screw loosening in patients." European Spine Journal, April 23, 2022. http://dx.doi.org/10.1007/s00586-022-07187-x.

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Abstract Purpose Pedicle screw loosening is a frequent complication in lumbar spine fixation, most commonly among patients with poor bone quality. Determining patients at high risk for insufficient implant stability would allow clinicians to adapt the treatment accordingly. The aim of this study was to develop a computational model for quantitative and reliable assessment of the risk of screw loosening. Methods A cohort of patient vertebrae with diagnosed screw loosening was juxtaposed to a control group with stable fusion. Imaging data from the two cohorts were used to generate patient-specif

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Scullen, Tyler, James Milburn, Kevin Aria, Mansour Mathkour, R. Shane Tubbs, and James Kalyvas. "The use of diffusion tensor imaging in spinal pathology: a comprehensive literature review." European Spine Journal, July 16, 2024. http://dx.doi.org/10.1007/s00586-024-08231-8.

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Abstract Study design We reviewed the available literature systematically without meta-analysis following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Objective To evaluate contemporary literature on use of spinal diffusion tensor imaging(sDTI) in spinal pathology. Background sDTI reveals the location and functional state of critical long tracts and is a potentially useful adjunct in disease management. Methods Studies were included if they presented or discussed data from investigative or therapeutic procedures involving sDTI on human subjects in the sett

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Kerensky, Max J., Abhijit Paul, Denis Routkevitch, et al. "Tethered spinal cord tension assessed via ultrasound elastography in computational and intraoperative human studies." Communications Medicine 4, no. 1 (2024). http://dx.doi.org/10.1038/s43856-023-00430-6.

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Abstract Background Tension in the spinal cord is a trademark of tethered cord syndrome. Unfortunately, existing tests cannot quantify tension across the bulk of the cord, making the diagnostic evaluation of stretch ambiguous. A potential non-destructive metric for spinal cord tension is ultrasound-derived shear wave velocity (SWV). The velocity is sensitive to tissue elasticity and boundary conditions including strain. We use the term Ultrasound Tensography to describe the acoustic evaluation of tension with SWV. Methods Our solution Tethered cord Assessment with Ultrasound Tensography (TAUT)

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Lehner, Kurt, Jeff Ehresman, Zach Pennington, A. Karim Ahmed, Daniel Lubelski, and Daniel M. Sciubba. "Narrative Review of Predictive Analytics of Patient-Reported Outcomes in Adult Spinal Deformity Surgery." Global Spine Journal, October 9, 2020, 219256822096306. http://dx.doi.org/10.1177/2192568220963060.

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Study Design: Narrative review Objective: Decision making in surgery for adult spinal deformity (ASD) is complex due to the multifactorial etiology, numerous surgical options, and influence of multiple medical and psychosocial factors on patient outcomes. Predictive analytics provide computational tools to analyze large data sets and generate hypotheses regarding new data. In this review, we examine the use of predictive analytics to predict patient-reported outcomes (PROs) in ASD surgery. Methods: A search of PubMed, Web of Science, and Embase databases was performed to identify all potential

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"Surfactal Software-Cad for Comparison-Dissection of Lumbar Spine Cadaveric Specimens with Biomedical Applications." Journal of Bioscience & Biomedical Engineering, March 20, 2021. http://dx.doi.org/10.47485/2693-2504.1034.

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The surfactal Computer Aided Design (CAD) and Computer Aided Manufacturing (CAM) constitute a modern method with multiple biomedical applications. This article presents a comparative-dissection study with different anterior lumbar spine cadaveric specimens, based on previous contribution advances. Two new unalike specimens are selected for CAD-CAM—Specimen 1 and Specimen 2. Improved programming for lumbar spine CAD is developed from former publications. Objective results demonstrate the amount of biomedical-surgical practical/ functional that can be obtained from computational surfaces of thes

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Caprara, Sebastiano, Fabio Carrillo, Jess G. Snedeker, Mazda Farshad, and Marco Senteler. "Automated Pipeline to Generate Anatomically Accurate Patient-Specific Biomechanical Models of Healthy and Pathological FSUs." Frontiers in Bioengineering and Biotechnology 9 (January 28, 2021). http://dx.doi.org/10.3389/fbioe.2021.636953.

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State-of-the-art preoperative biomechanical analysis for the planning of spinal surgery not only requires the generation of three-dimensional patient-specific models but also the accurate biomechanical representation of vertebral joints. The benefits offered by computational models suitable for such purposes are still outweighed by the time and effort required for their generation, thus compromising their applicability in a clinical environment. In this work, we aim to ease the integration of computerized methods into patient-specific planning of spinal surgery. We present the first pipeline c

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Maki, Satoshi, Takeo Furuya, Keiichi Katsumi, et al. "Multimodal Deep Learning-based Radiomics Approach for Predicting Surgical Outcomes in Patients with Cervical Ossification of the Posterior Longitudinal Ligament." Spine, July 8, 2024. http://dx.doi.org/10.1097/brs.0000000000005088.

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Study Design. A retrospective analysis. Objective. This research sought to develop a predictive model for surgical outcomes in patients with cervical ossification of the posterior longitudinal ligament (OPLL) using deep learning and machine learning (ML) techniques. Summary of Background Data. Determining surgical outcomes assists surgeons in communicating prognosis to patients and setting their expectations. Deep learning and ML are computational models that identify patterns from large datasets and make predictions. Methods. Of the 482 patients, 288 patients were included in the analysis. A

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Bacco, Luca, Fabrizio Russo, Luca Ambrosio, et al. "Natural language processing in low back pain and spine diseases: A systematic review." Frontiers in Surgery 9 (July 14, 2022). http://dx.doi.org/10.3389/fsurg.2022.957085.

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Natural Language Processing (NLP) is a discipline at the intersection between Computer Science (CS), Artificial Intelligence (AI), and Linguistics that leverages unstructured human-interpretable (natural) language text. In recent years, it gained momentum also in health-related applications and research. Although preliminary, studies concerning Low Back Pain (LBP) and other related spine disorders with relevant applications of NLP methodologies have been reported in the literature over the last few years. It motivated us to systematically review the literature comprised of two major public dat

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Casesnoves, Francisco. "Computational Simulations of the Anterior Vertebral Surface for Optimal Surgical Instrumentation Design." Journal of Medical Devices 4, no. 2 (2010). http://dx.doi.org/10.1115/1.3439667.

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The engineering design of surgical instrumentation to apply mechanical forces and linear moments on the human bones during the operations constitutes a rather difficult task. This is due both to the natural and pathological irregularities of the human bone morphology and surfaces and also to the individual variations from one patient to another. Usually, the forces are applied by the surgeon only on a determined part of the bone surfaces. This paper describes an innovative computational design method to digitalize, simulate, and fit mathematically the anterior vertebral body facet. We used rea

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Rasmussen, John, Kristoffer Iversen, Bjørn Keller Engelund, and Sten Rasmussen. "Biomechanical Evaluation of the Effect of Minimally Invasive Spine Surgery Compared with Traditional Approaches in Lifting Tasks." Frontiers in Bioengineering and Biotechnology 9 (October 18, 2021). http://dx.doi.org/10.3389/fbioe.2021.724854.

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Fusion of spinal vertebrae can be accomplished by different surgical approaches. We investigated Traditional Open Spine Surgery (TOSS) versus Minimally Invasive Spine Surgery (MISS). While TOSS sacrifices spine muscles originating or inserting on the affected vertebrae, MISS seeks to minimize the approach-related morbidity and preserve the tendon attachments of the muscles in the area. We captured 3-D motions of the full body of one healthy subject performing a variety of 10 kg box lifting operations representing activities-of-daily-living that are likely to challenge the spine biomechanically

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Anand, Adrish, Alex R. Flores, Malcolm F. McDonald, Ron Gadot, David S. Xu, and Alexander E. Ropper. "A computer vision approach to identifying the manufacturer of posterior thoracolumbar instrumentation systems." Journal of Neurosurgery: Spine, December 1, 2022, 1–8. http://dx.doi.org/10.3171/2022.11.spine221009.

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OBJECTIVE Knowledge of the manufacturer of the previously implanted pedicle screw systems prior to revision spinal surgery may facilitate faster and safer surgery. Often, this information is unavailable because patients are referred by other centers or because of missing information in the patients’ records. Recently, machine learning and computer vision have gained wider use in clinical applications. The authors propose a computer vision approach to classify posterior thoracolumbar instrumentation systems. METHODS Lateral and anteroposterior (AP) radiographs obtained in patients undergoing po

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Javeed, Saad, Justin K. Zhang, Jacob K. Greenberg, et al. "Electroactive Spinal Instrumentation for Targeted Osteogenesis and Spine Fusion: A Computational Study." International Journal of Spine Surgery, January 25, 2023, 8389. http://dx.doi.org/10.14444/8389.

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Li, Jingchi, Chen Xu, Xiaoyu Zhang, et al. "Disc measurement and nucleus calibration in a smoothened lumbar model increases the accuracy and efficiency of in-silico study." Journal of Orthopaedic Surgery and Research 16, no. 1 (2021). http://dx.doi.org/10.1186/s13018-021-02655-4.

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Abstract Backgrounds Finite element analysis (FEA) is an important tool during the spinal biomechanical study. Irregular surfaces in FEA models directly reconstructed based on imaging data may increase the computational burden and decrease the computational credibility. Definitions of the relative nucleus position and its cross-sectional area ratio do not conform to a uniform standard in FEA. Methods To increase the accuracy and efficiency of FEA, nucleus position and cross-sectional area ratio were measured from imaging data. A FEA model with smoothened surfaces was constructed using measured

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Shiiya, Norihiko, Naoki Washiyama, Daisuke Takahashi, et al. "Patency of separate tube grafts for intercostal artery reconstruction: Size and length matter." European Journal of Cardio-Thoracic Surgery, January 23, 2023. http://dx.doi.org/10.1093/ejcts/ezad023.

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Abstract Objectives Low patency is a major concern when using separate tube grafts for intercostal artery reconstruction. We aimed to elucidate the optimal size and length of grafts from the patency and computational fluid dynamics. Methods The patency, size, and length of separate tube grafts were evaluated in 41 patients. Computational fluid dynamics simulation was performed in a model derived from a patient with a patent 12-mm graft of 15 mm in length, with 2 simulation models with a smaller (8-mm) or longer (30-mm) graft. Results A total of 49 grafts were used for intercostal artery recons

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