Relevant bibliographies by topics / Spindle extension

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Spindle extension'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

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Journal articles on the topic "Spindle extension"

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Stephens, Andrew D., Rachel A. Haggerty, Paula A. Vasquez, et al. "Pericentric chromatin loops function as a nonlinear spring in mitotic force balance." Journal of Cell Biology 200, no. 6 (2013): 757–72. http://dx.doi.org/10.1083/jcb.201208163.

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The mechanisms by which sister chromatids maintain biorientation on the metaphase spindle are critical to the fidelity of chromosome segregation. Active force interplay exists between predominantly extensional microtubule-based spindle forces and restoring forces from chromatin. These forces regulate tension at the kinetochore that silences the spindle assembly checkpoint to ensure faithful chromosome segregation. Depletion of pericentric cohesin or condensin has been shown to increase the mean and variance of spindle length, which have been attributed to a softening of the linear chromatin sp
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Julius, Jeff, Jie Peng, Andrew McCulley, et al. "Inhibition of spindle extension through the yeast S phase checkpoint is coupled to replication fork stability and the integrity of centromeric DNA." Molecular Biology of the Cell 30, no. 22 (2019): 2771–89. http://dx.doi.org/10.1091/mbc.e19-03-0156.

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Budding yeast treated with hydroxyurea (HU) activate the S phase checkpoint kinase Rad53, which prevents DNA replication forks from undergoing aberrant structural transitions and nuclease processing. Rad53 is also required to prevent premature extension of the mitotic spindle that assembles during a HU-extended S phase. Here we present evidence that checkpoint restraint of spindle extension is directly coupled to Rad53 control of replication fork stability. In budding yeast, centromeres are flanked by replication origins that fire in early S phase. Mutations affecting the Zn2+-finger of Dbf4,
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Zarbo, Richard J., Mark T. Marunick, and Robert Johns. "Malignant Ameloblastoma, Spindle Cell Variant." Archives of Pathology & Laboratory Medicine 127, no. 3 (2003): 352–55. http://dx.doi.org/10.5858/2003-127-0352-mascv.

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Abstract In this report, we document the histologic and clinical features of a previously undefined spindle cell variant of ameloblastoma that eventually behaved in a malignant fashion during a protracted course. The predominant histologic pattern was a well-differentiated, cellular, spindled epithelial proliferation arising in the maxilla of a 14-year-old African American girl. Over 19 years, the patient experienced numerous local recurrences, metastases to distant bones after 15 years, and finally bulky local recurrence with intracranial extension resulting in death. This ameloblastic malign
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Khmelinskii, Anton, Clare Lawrence, Johanna Roostalu, and Elmar Schiebel. "Cdc14-regulated midzone assembly controls anaphase B." Journal of Cell Biology 177, no. 6 (2007): 981–93. http://dx.doi.org/10.1083/jcb.200702145.

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Spindle elongation in anaphase of mitosis is a cell cycle–regulated process that requires coordination between polymerization, cross-linking, and sliding of microtubules (MTs). Proteins that assemble at the spindle midzone may be important for this process. In this study, we show that Ase1 and the separase–Slk19 complex drive midzone assembly in yeast. Whereas the conserved MT-bundling protein Ase1 establishes a midzone, separase–Slk19 is required to focus and center midzone components. An important step leading to spindle midzone assembly is the dephosphorylation of Ase1 by the protein phosph
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Bachant, Jeff, Shannon R. Jessen, Sarah E. Kavanaugh, and Candida S. Fielding. "The yeast S phase checkpoint enables replicating chromosomes to bi-orient and restrain spindle extension during S phase distress." Journal of Cell Biology 168, no. 7 (2005): 999–1012. http://dx.doi.org/10.1083/jcb.200412076.

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The budding yeast S phase checkpoint responds to hydroxyurea-induced nucleotide depletion by preventing replication fork collapse and the segregation of unreplicated chromosomes. Although the block to chromosome segregation has been thought to occur by inhibiting anaphase, we show checkpoint-defective rad53 mutants undergo cycles of spindle extension and collapse after hydroxyurea treatment that are distinct from anaphase cells. Furthermore, chromatid cohesion, whose dissolution triggers anaphase, is dispensable for S phase checkpoint arrest. Kinetochore–spindle attachments are required to pre
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Nabeshima, Kentaro, Takashi Nakagawa, Aaron F. Straight, et al. "Dynamics of Centromeres during Metaphase–Anaphase Transition in Fission Yeast: Dis1 Is Implicated in Force Balance in Metaphase Bipolar Spindle." Molecular Biology of the Cell 9, no. 11 (1998): 3211–25. http://dx.doi.org/10.1091/mbc.9.11.3211.

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In higher eukaryotic cells, the spindle forms along with chromosome condensation in mitotic prophase. In metaphase, chromosomes are aligned on the spindle with sister kinetochores facing toward the opposite poles. In anaphase A, sister chromatids separate from each other without spindle extension, whereas spindle elongation takes place during anaphase B. We have critically examined whether such mitotic stages also occur in a lower eukaryote, Schizosaccharomyces pombe. Using the green fluorescent protein tagging technique, early mitotic to late anaphase events were observed in living fission ye
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Yu, Wei, Lucy E. O'Brien, Fei Wang, Henry Bourne, Keith E. Mostov, and Mirjam M. P. Zegers. "Hepatocyte Growth Factor Switches Orientation of Polarity and Mode of Movement during Morphogenesis of Multicellular Epithelial Structures." Molecular Biology of the Cell 14, no. 2 (2003): 748–63. http://dx.doi.org/10.1091/mbc.e02-06-0350.

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Epithelial cells form monolayers of polarized cells with apical and basolateral surfaces. Madin-Darby canine kidney epithelial cells transiently lose their apico-basolateral polarity and become motile by treatment with hepatocyte growth factor (HGF), which causes the monolayer to remodel into tubules. HGF induces cells to produce basolateral extensions. Cells then migrate out of the monolayer to produce chains of cells, which go on to form tubules. Herein, we have analyzed the molecular mechanisms underlying the production of extensions and chains. We find that cells switch from an apico-basol
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Dhoke, Priti Rakesh, Vivek Vishwasji Harkare, Nitin Vasant Deosthale, Sonali Prabhakar Khadakkar, Kanchan Sandeep Dhote, and Gopal Gurjar. "Spindle Cell Sarcoma of Submandibular Salivary Gland: A Rare Presentation." International Journal of Head and Neck Surgery 2, no. 3 (2011): 144–45. http://dx.doi.org/10.5005/jp-journals-10001-1070.

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ABSTRACT Objective To report a rare case of spindle cell sarcoma of submandibular salivary gland, with intraoral extension with pathological dilemma. Case report A 40-year-old male presented with swelling and pain in right submandibular area since 1 year. Right submandibular gland excision with intraoral mass excision was done with reconstruction of floor of mouth. Postoperative histopathology was suggestive of low-grade malignant tumor with differential diagnosis of acinic cell tumor, vascular tumor and myoepithelial tumor. The immunohistochemistry report revealed spindle cell sarcoma with hi
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Matsson, Leif. "Spindle checkpoint regulated by nonequilibrium collective spindle-chromosome interaction; relationship to single DNA molecule force-extension formula." Journal of Physics: Condensed Matter 21, no. 50 (2009): 502101. http://dx.doi.org/10.1088/0953-8984/21/50/502101.

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Li, Xiaohu, Ke Yan, Yifa Lv, Bei Yan, Lei Dong, and Jun Hong. "Study on the influence of machine tool spindle radial error motion resulted from bearing outer ring tilting assembly." Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science 233, no. 9 (2018): 3246–58. http://dx.doi.org/10.1177/0954406218802324.

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To reveal the spindle radial error motion characteristics in condition of bearing outer ring tilting assembly, mathematical method on spindle radial error motion were analyzed. Then, in real operation condition the natural frequency of the test rig was investigated. Experimental system and methods were designed to test axial thermal displacement, radial error motion and modal characteristic of spindle in condition of bearing outer ring tilting assembly. Results show that axial thermal extension and radial vertical rising of spindle front-end occurs during thermal displacement test. With the sa
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Dissertations / Theses on the topic "Spindle extension"

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Raszka, Pavel. "Vývoj vřeteníku pro horizontální vyvrtávací centrum." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2019. http://www.nusl.cz/ntk/nusl-401042.

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The master´s thesis deals with the design of the headstock for the horizontal boring center and design of the milling head. In the first part of the thesis, a search is made in the field of boring machines, main parts of boring machine headstock and milling heads. Based on this theoretical analysis, the input parameters for the calculation of the tension, power and torque characteristics of the headstock are selected. Subsequently, the design of the headstock and milling head is done using a 3D model.
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Kardouni, Joseph. "Effects of Thoracic Spinal Manipulative Therapy on Thoracic Spine and Shoulder Kinematics, Thoracic Spine Flexion/Extension Excursion, and Pressure Pain Sensitivity in Patients with Subacromial Pain Syndrome." VCU Scholars Compass, 2013. http://scholarscompass.vcu.edu/etd/3304.

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EFFECTS OF THORACIC SPINAL MANIPULATIVE THERAPY ON THORACIC SPINE AND SHOULDER KINEMATICS, THORACIC SPINE FLEXION/EXTENSION EXCURSION, AND PRESSURE PAIN SENSITIVITY IN PATIENTS WITH SUBACROMIAL PAIN SYNDROME By Joseph R. Kardouni, Ph.D., PT A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy, at Virginia Commonwealth University. Virginia Commonwealth University, 2013. Major Director: Lori A. Michener, PhD, PT, ATC, Professor, Department of Physical Therapy In patients with shoulder pain, the use of manual therapy directed at the spine and
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Daggfeldt, Karl. "Biomechanics of back extension torque production about the lumbar spine /." Stockholm : Karolinska Univ. Press, 2002. http://diss.kib.ki.se/2002/91-7349-107-1/thesis.pdf.

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Lee, Minhyung. "Analysis of Lumbar Spine Kinematics during Trunk Flexion and Extension Motions." Thesis, Virginia Tech, 2006. http://hdl.handle.net/10919/31003.

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The effectiveness of exercise has been increasingly studied as exercise has been popular for the improvement of physical performance and rehabilitation of lumbar spine. A variety of exercises have been used to reduce back pain or spinal degeneration. However, there are no studies to determine effects of exercise on lumbar spine kinematics, including lumbar-pelvic coordination and instantaneous axis of rotation. The current study aimed to examine these lumbar spine kinematical changes due to exercise and therapy. We hypothesized that exercise and therapy will affect the changes of lumbar spine
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Singer, Mathew Kyle. "Self powered wrist extension orthosis." Thesis, University of Canterbury. Mechanical Engineering, 2006. http://hdl.handle.net/10092/1154.

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One of the most devastating effects of tetraplegia is the inability to grasp and manipulate everyday objects necessary to living an independent life. Currently surgery is widely accepted as the solution to improve hand functionality. However, surgery becomes difficult when the user has paralysed wrists as is the case with C5 tetraplegia. The aim of this research was to develop a solution which provided controlled wrist flexion and extension which, when combined with surgery, achieves a 'key pinch' grip. This particular grip is critically important for people with C5 tetraplegia as it is used f
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Gottipati, Pranitha. "Experimental and Simulation Based Dynamic Assessment of Flexion and Extension Movements of Torso." Diss., Virginia Tech, 2009. http://hdl.handle.net/10919/40426.

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Low back disorders (LBDs) comprise one of the major health issues in the United States. Previous research used isometric studies to understand the mechanisms that cause LBDs. Occupational tasks involving dynamic trunk movements, muscle fatigue, and spinal instability are identified as major risk factors for developing low back pain. Dynamic stability and muscle forces during trunk flexion-extension movements are studied in this dissertation. Torso muscle fatigue is known to affect the neuromuscular muscle recruitment that influences spinal stability. The first part of this dissertation
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Giuffrida, Joseph P. "Synergistic Neural Network Control of FES Elbow Extension After Spinal Cord Injury Using EMG." Case Western Reserve University School of Graduate Studies / OhioLINK, 2004. http://rave.ohiolink.edu/etdc/view?acc_num=case1081513453.

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Sparto, Patrick J. "Trunk muscle electromyographic responses, spinal loading, and wavelet detection of fatigue during repetitive trunk extension /." The Ohio State University, 1998. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487949508369749.

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Davidson, Bradley Steven. "Biomechanical Evaluation of Lumbar Extensor Fatigue Effects on the Postural Control System." Thesis, Virginia Tech, 2005. http://hdl.handle.net/10919/30929.

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Falls from heights are the fourth leading cause of occupational injury and fatality in the United States. In particular, construction workers such as roofers are often exposed to high risk environments. Recent research has reported that a leading cause of falls among workers is a loss of balance. Therefore, in moving towards reducing the number of occupational falls, further investigation of balance and factors that influence postural control is necessary. The effect of neuromuscular fatigue has been addressed by many investigators; however, few studies have examined the effect of localize
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McNamara, Michelle. "Longitudinal extension of primary afferents is regulated by spingosine 1-phosphate receptors and tyrosine kinase receptor B in the embryonic spinal cord via a brain derived neurotrophic factor related mechanism." ScholarWorks @ UVM, 2015. http://scholarworks.uvm.edu/graddis/408.

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Primary sensory afferent outgrowth within the developing longitudinal pathway of the spinal cord is important for intrasegmental and intersegmental communication that underlies coordination and development of reflexes and contributes to sensory perception. The endogenous mechanisms that regulate primary sensory afferent extension are the primary focus of this dissertation. This dissertation tested the hypothesis that primary sensory afferent extension in the longitudinal pathway is regulated by sphingosine 1-phosphate type 1 receptor (S1P1R) and tyrosine kinase receptor B (TrkB) through a brai
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Books on the topic "Spindle extension"

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Gala, Raj J., and James Yue. Lumbar Neurogenic Claudication. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190626761.003.0010.

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Lumbar neurogenic claudication, sometimes referred to as pseudoclaudication, is the clinical syndrome of back pain radiating down one or both legs during ambulation. Classically, the symptoms abate with forward flexion of the lumbar spine and worsen with extension. The condition arises from lumbar spinal stenosis, which is common in the elderly population. Many asymptomatic individuals have lumbar spinal stenosis seen on magnetic resonance imaging (MRI), so this syndrome is a clinical diagnosis. The majority of patients have favorable responses with conservative treatment, which includes physi
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Aans Publications Committee. Surgical Exposure of the Spine: An Extensile Approach. American Association of Neurological Surgeons, 1995.

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West, Tyler R., and Kelly J. Baldwin. Spinal and Intracranial Epidural Abscess, and Subdural Empyema. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0151.

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A spinal epidural abscess is an infection that resides in the epidural space of the spinal canal, and most commonly occurs from hematogenous seeding or direct extension from adjacent structures. Normal skin flora such as Staphylococcus and Streptococcus spp are the most common organisms to cause an epidural abscess, typically when host immunity is compromised or due to barrier disruption. The clinical presentation is heterogeneous, but often will progress over time to spinal cord compression. Intracranial epidural abscess and subdural empyema occur within the skull and are frequently spread vi
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Baraliakos, Xenofon, and Kay-Geert A. Hermann. Imaging: spine. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198734444.003.0014.

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Although axial spondyloarthritis (axSpA) starts in the sacroiliac joints in the vast majority of cases, the spine can be clinically affected with similar severity and frequency, especially in long-standing disease. In addition, not only the inflammatory but also structural changes seen in the sacroiliac joints can be visualized in the same way in the spine when using the appropriate imaging techniques. For the interpretation of imaging findings in axSpA, typical and frequent differential diagnoses need to be taken into account, such as degenerative changes, bacterial inflammation, and fracture
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Burke, David. Motor control: spinal and cortical mechanisms. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199688395.003.0003.

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There is extensive machinery at cerebral and spinal levels to support voluntary movement, but spinal mechanisms are often ignored by clinicians and researchers. For movements of the upper and lower limbs, what the brain commands can be modified or even suppressed completely at spinal level. The corticospinal system is the executive pathway for movement arising largely from primary motor cortex, but movement is not initiated there, and other pathways normally contribute to movement. Greater use of these pathways can allow movement to be restored when the corticospinal system is damaged by, e.g.
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Hafez, Daniel, Adam Bevan, and Wilson Z. Ray. Nerve Transfers for Spinal Cord Injury. Edited by Meghan E. Lark, Nasa Fujihara, and Kevin C. Chung. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190617127.003.0029.

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In spinal cord injury, nerve transfers represent a potential adjunct in the comprehensive clinical management of patients. Unlike tendon transfers, nerve transfers preserve the native muscle biomechanics and provide greater than a 1:1 functional exchange. Nerve transfers can provide improved upper extremity function by capitalizing on the preserved upper motor neurons below the zone of spinal cord injury. One goal in reconstruction is to restore movement. Major movements that have been targeted for restoration include elbow extension (to allow the patient to assist in transfers) and pinch, gra
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Pham, Martin H., and Patrick C. Hsieh. Primary Tumors of the Spine. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190696696.003.0022.

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Primary tumors of the spinal column are rare. Computed tomography–guided biopsy is typically performed to make the diagnosis and plan the next steps in treatment. For some primary spinal column tumors, such as osteosarcoma, en bloc resection based on the Enneking classification and extensive spinal reconstruction may be indicated. Significant surgical complications are possible with en bloc resection, and extensive preoperative counseling is required. Patients with pre-existing metastatic disease will likely not benefit from en bloc resection and instead may undergo debulking surgery based on
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Elnaggar, Ibrahim Magdy. THE EFFECTS OF SPINAL FLEXION AND EXTENSION EXERCISES ON LOW BACK PAIN SEVERITY AND SPINAL MOBILITY IN CHRONIC MECHANICAL LOW BACK PAIN. 1988.

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Chapman, Jens R., and Richard J. Bransford. Emergency management of the traumatized cervical spine. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199550647.003.012038.

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♦ Unconscious patients should have CT scan of neck♦ Emergency MRI if possible in spinal cord injury♦ Avoid flexion/extension views if possible♦ In spinal shock avoid over transfusion and consider epinephrine; high dose steroids probably not indicated♦ Reduce dislocation acutely (MRI before in intact patients if possible)♦ Do not put distraction injury into traction♦ Urgent surgery for traumatic disc hernaition, expanding epidural haematoma, depressed lamina fracture or complex facet fractures with dislocation.
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Speed, Cathy. Badminton injuries. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199533909.003.0054.

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The sport of badminton originated in Gloucestershire, England, in the 1860s and has evolved to become a game played by millions across the world. Badminton is the world’s fastest racket sport with shuttles reaching 200 mph in top international competitions. When played at high level, this fast and powerful game demands high levels of strength, agility, endurance, and tactical awareness. Most of the injuries seen are related to microtraumatic overuse, and are associated with high impact, lunging, rotating, and spinal extension. The mechanics of the sport present a good example of the influence
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Book chapters on the topic "Spindle extension"

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Gracovetsky, Serge. "The Calculated Response of the Spine in Flexion-Extension." In The Spinal Engine. Springer Vienna, 1988. http://dx.doi.org/10.1007/978-3-7091-8951-1_6.

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Gracovetsky, Serge. "The Measured Response of the Spine in Flexion-Extension." In The Spinal Engine. Springer Vienna, 1988. http://dx.doi.org/10.1007/978-3-7091-8951-1_7.

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Hovorka, Istvàn, and Derek Thomas Cawley. "The Reserve of Hip Extension and Its Relationship with the Spine." In Spinal Anatomy. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-20925-4_7.

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Noth, J. "Group I and II effects on extensor gamma motoneurones revealed by repetitive muscle nerve stimulation in the cat." In The Muscle Spindle. Palgrave Macmillan UK, 1985. http://dx.doi.org/10.1007/978-1-349-07695-6_38.

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Gracovetsky, Serge. "A Model of the Spine in Flexion-Extension : Mathematical Formulation." In The Spinal Engine. Springer Vienna, 1988. http://dx.doi.org/10.1007/978-3-7091-8951-1_5.

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Cusick, J. F. "Extensive Posterior Fusion for Cervical Spondylotic Myelopathy." In Cervical Spine I. Springer Vienna, 1987. http://dx.doi.org/10.1007/978-3-7091-8882-8_51.

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Srivastava, Arun K., Jayesh Sardhara, Chaitanya Godbole, and Sanjay Behari. "Surgical Treatment of Spinal Tuberculosis Complicated with Extensive Abscess." In Tuberculosis of the Central Nervous System. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-50712-5_31.

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González-Sánchez, M., and A. I. Cuesta-Vargas. "Functional and Structural of the Erector Spinae Muscle during Isometric Lumbar Extension." In IFMBE Proceedings. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-00846-2_31.

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Sherman, J. L., S. E. Kopits, and C. M. Citrin. "The Craniocervical Junction in Skeletal Dysplasia: MRI in Flexion and Extension." In Imaging of Brain Metabolism Spine and Cord Interventional Neuroradiology Free Communications. Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74337-5_28.

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Soukup, T. "Regeneration of Muscle Spindles in Grafted Extensor Digitorum Longus Muscle of the Rat." In Mechanoreceptors. Springer US, 1988. http://dx.doi.org/10.1007/978-1-4899-0812-4_20.

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Conference papers on the topic "Spindle extension"

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Zhang, Longiia, Xi Zhang, Xiangwei Liu, and Zixie Guo. "Inspection and Compensation of Spindle Thermal Extension Based on Machine Vision." In 2020 IEEE International Conference on Mechatronics and Automation (ICMA). IEEE, 2020. http://dx.doi.org/10.1109/icma49215.2020.9233704.

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Abraham, P. M., and S. E. Wilson. "Effects of a Lumbar Belt on Neuromotor Transmission of Whole Body Vibration." In ASME 2007 International Mechanical Engineering Congress and Exposition. ASMEDC, 2007. http://dx.doi.org/10.1115/imece2007-42358.

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Whole body vibration (WBV) has been identified as a risk factor for low back musculoskeletal disorders and injuries. One potential mechanism by which WBV may lead to low back injury is through stimulation of muscle spindle organs and repetitive activation of the stretch-reflex neuromotor response. Such repetitive activation could lead to muscular fatigue and/or neuromotor adaptation. Understanding mechanical transmission of vibration to the neuromotor system and the resulting neuromotor activation is critical to understanding these mechanisms. In this study, it was theorized that activation of
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Dassanayake, K. M. Muditha, Ken Yamamot, and Masaomi Tsutsumi. "A Methodology for Identifying Inherent Deviations in Universal Spindle Head Type Multi-Axis Machines by Simultaneous Five-Axis Control Motions." In ASME 2006 International Mechanical Engineering Congress and Exposition. ASMEDC, 2006. http://dx.doi.org/10.1115/imece2006-13440.

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In this paper, two different simulataneous five-axis control motions were newly proposed to identify the ten inherent deviations in universal spindle head type multi-axis machines. The ball bar was used as a measuring device. Both of the two motions were carried out bu using a single setup which was a simple extension bar. This leads to reduce non-productive time of the operator within the machine work space. Three measurments were used to estimate the ten deviations in which two measurements were extracted by means of axial direction motion and the other by tangential direction motion. By usi
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Liu, Zheng, Yan-Feng Li, Yuan-Jian Yang, Jinhua Mi, and Hong-Zhong Huang. "Extensions of Bayesian Reliability Analysis by Using Imprecise Dirichlet Model." In ASME 2015 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/detc2015-47183.

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Bayesian approaches have been demonstrated as effective methods for reliability analysis of complex systems with small-amount data, which integrate prior information and sample data using Bayes’ theorem. However, there is an assumption that precise prior probability distributions are available for unknown parameters, yet these prior distributions are sometimes unavailable in practical engineering. A possible way to avoiding this assumption is to generalize Bayesian reliability analysis approach by using imprecise probability theory. In this paper, we adopt a set of imprecise Dirichlet distribu
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Vaughan, Neil, Venketesh N. Dubey, Michael Y. K. Wee, and Richard Isaacs. "Spine Flexion and Extension Model for Epidural Simulator." In ASME 2014 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/detc2014-35709.

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The aim of this research was to create novel computer graphics models of the human spine which can bend, flex and twist. The model aims to realistically duplicate the shape of the spine during various sitting positions adopted by patients during epidural anaesthesia and surgery. The extent of bending and flexing is kept within the limits of spine flexibility. Also the model vertebrate adapt in size and shape to match weight and height of specific patient bodies. The flexible spine model can be of benefit to epidural simulators which require accurate models of spinal vertebrae for needle insert
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Bahramshahi, N., H. Ghaemi, and K. Behdinan. "Finite Element Study of Spinal Cord Mechanics During Biomechanical Response of Middle Cervical Spine." In ASME 2010 International Mechanical Engineering Congress and Exposition. ASMEDC, 2010. http://dx.doi.org/10.1115/imece2010-40573.

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The present study is conducted to develop a detailed FE model of spinal cord and to study its behaviour under various loading conditions. To achieve the goal, a previously developed and validated FE model of the middle cervical spine (C3-C5) is utilized. The model is further modified to investigate the stresses that the spinal cord in experiences during cervical spine motion segment in compression and flexion/extension loading modes. The resulting Von Misses stress and axial strain of the anterior and posterior surfaces of the cervical spinal cord are obtained from a set of elements along the
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DiAngelo, Denis J., Elizabeth J. Sander, Nephi A. Zufelt, Brian P. Kelly, and Kevin T. Foley. "Low Endurance Testing of a Spinous Process Spacer." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-192985.

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Lumbar neurogenic claudication secondary to spinal stenosis causes narrowing of the spinal canal that contributes to extremity lower back pain. Lumbar extension, as seen in standing and walking, exacerbates symptoms by decreasing the foraminal height, width, and area, whereas flexion, as seen in sitting, improves symptoms by increasing the cross-sectional area of the foramen. Interspinous process devices have been developed to treat symptomatic lumbar stenosis [1]. The device is placed between the spinous processes and serves to limit the amount of extension that can occur beyond a neutral ali
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8

Adams, Maurice L., and Michael A. Laurich. "Design, Analysis and Testing of an Inside-Out Tilting-Pad Journal Bearing With Real-Time Controllable Preload and Stiffness." In World Tribology Congress III. ASMEDC, 2005. http://dx.doi.org/10.1115/wtc2005-63067.

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It has recently been shown that high-speed grinding can be applied to the finishing of ceramics with considerable improvements in throughput and quality. This will require new high-speed high-power centerless grinding spindles (7,000 RPM, 50 HP), with high-stiffness of three hundred and fifty million Newtons/meter (2 million lb/in). To meet these requirements a novel inside-out, three-pad, pivoting-pad oil-fed hydrodynamic journal bearing has been devised, built and tested. One of the three pad’s pivot point is supported by a hydraulically-actuated radial-motion loading piston. This provides r
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9

Parikh, Rachit, Amanesh Amanesh, Ali Kiapour, Vijay K. Goel, and Celeste Abjornson. "Biomechanical Investigation and Bone-Implant Stress Analysis of a Novel Lumbar Interspinous Spacer." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206870.

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Spinal stenosis usually presents with pain radiating beyond the back to the buttocks, thighs or lower legs. The pain is worsened with extension of the lumbar spine and improves with flexion of the spine. Interspinous spacers are a relatively new treatment option that can be implanted under the minimal spinal surgical procedure. The Interspinous process devices are designed to distract (open) the foramen, where the nerve endings pass away from the center of the spinal region and into the legs. There have been many studies on the motion but stress distributions in the spine and the device are sp
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10

DeVries, Nicole A., Anup A. Gandhi, Douglas C. Fredericks, Joseph D. Smucker, and Nicole M. Grosland. "In Vitro Study of the C2-C7 Sheep Cervical Spine." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53167.

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Due to the limited availability of human cadaveric specimens, animal models are often utilized for in vitro studies of various spinal disorders and surgical techniques. Sheep spines have similar geometry, disc space, and lordosis as compared to humans [1,2]. Several studies have identified the geometrical similarities between the sheep and human spine; however these studies have been limited to quantifying the anatomic dimensions as opposed to the biomechanical responses [2–3]. Although anatomical similarities are important, biomechanical correspondence is imperative to understand the effects
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