Academic literature on the topic 'Spirostan saponin'

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Journal articles on the topic "Spirostan saponin"

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Dąbrowska-Balcerzak, Karolina, Jadwiga Nartowska, Iwona Wawer, Paweł Siudem, and Katarzyna Paradowska. "Spirostanol Sapogenins and Saponins from Convallaria majalis L. Structural Characterization by 2D NMR, Theoretical GIAO DFT Calculations and Molecular Modeling." Molecules 26, no. 10 (2021): 2999. http://dx.doi.org/10.3390/molecules26102999.

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Two new spirostanol sapogenins (5β-spirost-25(27)-en-1β,2β,3β,5β-tetrol 3 and its 25,27-dihydro derivative, (25S)-spirostan-1β,2β,3β,5β-tetrol 4) and four new saponins were isolated from the roots and rhizomes of Convallaria majalis L. together with known sapogenins (isolated from Liliaceae): 5β-spirost-25(27)-en-1β,3β-diol 1, (25S)-spirostan-1β,3β-diol 2, 5β-spirost-25(27)-en-1β,3β,4β,5β-tetrol 5, (25S)-spirostan-1β,3β,4β,5β-tetrol 6, 5β-spirost-25(27)-en-1β,2β,3β,4β,5β-pentol 7 and (25S)-spirostan-1β,2β,3β,4β,5β-pentol 8. New steroidal saponins were found to be pentahydroxy 5-O-glycosides; 5
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Pérez-Labrada, Karell, Ignacio Brouard, Cercis Morera, Francisco Estévez, Jaime Bermejo, and Daniel G. Rivera. "‘Click’ synthesis of triazole-based spirostan saponin analogs." Tetrahedron 67, no. 40 (2011): 7713–27. http://dx.doi.org/10.1016/j.tet.2011.08.003.

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Higano, Taro, Minpei Kuroda, Maki Jitsuno, and Yoshihiro Mimaki. "Polyhydroxylated Steroidal Saponins from the Rhizomes of Convallaria majalis." Natural Product Communications 2, no. 5 (2007): 1934578X0700200. http://dx.doi.org/10.1177/1934578x0700200504.

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Six new polyhydroxylated spirostanol saponins (1–6) were isolated from the methanolic extract of the rhizomes of Convallaria majalis. On the basis of extensive spectroscopic analysis, including 2D NMR data, and a few chemical transformations, the structures of 1–6 were determined to be 1β,2β,3β-trihydroxy-5β-spirost-25(27)-en-5-yl β-D-galactopyranoside (1), (25 S)-1β,2β,3β-trihydroxy-5β-spirostan-5-yl β-D-galactopyranoside (2), 1β,2β,3β,4β-tetrahydroxy-5β-spirost-25(27)-en-5-yl β-D-galactopyranoside (3), (25 S)-1β,2β,3β,4β-tetrahydroxy-5β-spirostan-5-yl β-D-galactopyranoside (4), 1β,2β,3β,4β-t
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Alvarez, Laura, Maria del Carmen Pérez, José Luis González, Victor Navarro, Maria Luisa Villarreal, and John Otto Olson. "SC-1, An Antimycotic Spirostan Saponin from Solanum chrysotrichum." Planta Medica 67, no. 4 (2001): 372–74. http://dx.doi.org/10.1055/s-2001-14332.

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D., N. Singh, and Verma N. "Furostan saponin and GC-MS study toward ascertaining the point of linkage between sugars moieties of spirostan saponin from the rhizomes of Agapanthus africanus (Linn.)." Journal Of Indian Chemical Society Vol. 87, Aug 2010 (2010): 999–1003. https://doi.org/10.5281/zenodo.5801240.

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Department of Chemistry, K. S. Saket PG College, Dr. Ram Manohar Lohia Avadh University, Faizabad-224 001, Uttar Pradesh, India E-mail : dnsinghsaket@yahoo.com Manuscript received 26 October 2008, revised 9 February 2010, accepted 25 February 2010 The linkage between the sugars moieties of antifungal spirostan saponin, (25<em>R</em>)-5&alpha;-spirost-7-en-2&alpha;,3&beta;,5&alpha;-trioi-3-<em>O</em>-{-<em>O</em>-&alpha;-L-rhamnopyranosyl-(1&rarr;2)-<em>O</em>-[&beta;-D-galactopyranosyi-(1&rarr;3))&middot;P&middot;D-glucopyranoside} of Agapa11thus africanus (Linn.) have been determined by the a
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Silva, Graziela M., Aloa M. De Souza, Luciene S. Lara, et al. "A New Steroidal Saponin from Agave brittoniana and Its Biphasic Effect on the Na+-ATPase Activity." Zeitschrift für Naturforschung C 60, no. 1-2 (2005): 121–27. http://dx.doi.org/10.1515/znc-2005-1-222.

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A new steroidal saponin, 3-{(O-6-deoxy-α-ʟ-mannopyranosyl-(1→4)-O-β-ᴅ-glucopyranosyl-( 1→3)-O-[O-β-ᴅ-glucopyranosyl-(1→3)-β-ᴅ-glucopyranosyl-(1→2)]-O-β-ᴅ-glucopyranosyl-( 1→4)-β-ᴅ-galactopyranosyl)oxy}-6-hydroxy-(3β,5α,6α,25R)-spirostan-12-one, was isolated from Agave brittoniana Trel. The structure was determined by extensive NMR spectroscopy studies and chemical conversions. Its effects on the Na+-ATPase and (Na++K+)-ATPase activities of the proximal tubule from pig kidney were evaluated. It was observed that this steroidal saponin exerts a biphasic effect on the Na+-ATPase activity. It is c
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Candra, Ellyawati, Kimihiro Matsunaga, Hironori Fujiwara, et al. "Two steroidal saponins from Camassia cusickii induce L1210 cell death through the apoptotic mechanism." Canadian Journal of Physiology and Pharmacology 79, no. 11 (2001): 953–58. http://dx.doi.org/10.1139/y01-068.

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Two steroidal saponins, tigogenin hexasaccharide-1 (TGHS-1, (25R)-5α-spirostan-3β-yl 4-O-[2-O-[3-O- (α-L-rhamnopyranosyl)-β-D-glucopyranosyl]-3-O-[4-O-(α-L-rhamnopyranosyl)-β-D-glucopyranosyl]-β-D-glucopyranosyl]- β-D-galactopyranoside) and tigogenin hexasaccharide-2 (TGHS-2, (25R)-5α-spirostan-3β-yl 4-O-[2-O-[3-O- (β-D-glucopyranosyl)-β-D-glucopyranosyl]-3-O-[4-O-(α-L-rhamnopyranosyl)-β-D-glucopyranosyl]-β-D-glucopyranosyl]- β-D-galactopyranoside), were isolated from the fresh bulbs of Camassia cusickii. In murine leukemic L1210 cells, both compounds showed cytotoxicity with an EC50 value of
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Li, Ming, and Biao Yu. "Facile Conversion of Spirostan Saponin into Furostan Saponin: Synthesis of Methyl Protodioscin and Its 26-Thio-analogue." Organic Letters 8, no. 13 (2006): 2679–82. http://dx.doi.org/10.1021/ol060594w.

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Okubo, Shinya, Tomoe Ohta, Yukihiro Shoyama, and Takuhiro Uto. "Steroidal Saponins Isolated from the Rhizome of Dioscorea tokoro Inhibit Cell Growth and Autophagy in Hepatocellular Carcinoma Cells." Life 11, no. 8 (2021): 749. http://dx.doi.org/10.3390/life11080749.

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Our preliminary screening identified an extract from the rhizome of Dioscorea tokoro, which strongly suppressed the proliferation of HepG2 hepatocellular carcinoma cells and inhibited autophagy. This study aimed to isolate active compounds from the rhizome of D. tokoro that exert antiproliferative effects and inhibit autophagy. The bioassay-guided fractionation of the active fraction led to the isolation of two spirostan-type steroidal saponins, dioscin (1) and yamogenin 3-O-α-l-rhamnopyranosyl (1→4)-O-α-l-rhamnopyranosyl(1→2)-β-d-glucopyranoside (2), and the frostane-type steroidal saponin pr
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Ren, Rui, Ming-yan Zhang, Tengyun Shu, Ya-ting Kong, Li-hua Su, and Hai-zhou Li. "Steroidal Saponins from Water Eggplant (Fruits of Solanum torvum) Exhibit Anti-Epileptic Activity against Pentylenetetrazole-Induced Seizure Model in Zebrafish." Molecules 29, no. 6 (2024): 1316. http://dx.doi.org/10.3390/molecules29061316.

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The fruits of Solanum torvum Swartz, a wild relative of eggplant, are consumed as a wild vegetable in tropical regions of Africa, Asia, and South America. In traditional Chinese medicine, it is believed to have anti-inflammatory and sedative effects. In the Philippines, water decoction is used to treat hyperactivity disorder. Twenty-two steroidal saponins were isolated and purified from the fruits grown in Yunnan, China, including six new compounds: torvosides U–Z (1–6). During drying and cooking, the saponins may undergo transformation, resulting in small amounts of sapogenins. These transfor
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Dissertations / Theses on the topic "Spirostan saponin"

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Upadhyay, Sunil. "Synthesis and Antifungal Evaluation of Spirostane Saponins." ScholarWorks@UNO, 2011. http://scholarworks.uno.edu/td/1414.

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Methods for the preparation of novel antifungal saponins have been investigated in order to further explore their medicinal utility and provide the opportunity to synthesize their derivatives. Through this work, several partially protected stereoisomers of Cholestane, Androstane and Spirostane have been prepared which could be used for the synthesis of various saponin derivatives in order to discover novel saponin based antifungal agent. Various mono and disaccharide derivatives of these steroids have been synthesized and evaluated for their antifungal activity against four pathogenic fungal s
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Bowdy, Katharine. "Toward the Synthesis of CAY-1, an Antifungal Steroidal Saponin." ScholarWorks@UNO, 2007. http://scholarworks.uno.edu/td/545.

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Invasive fungal infections are prevalent and often deadly in immunocompromised patients. There continues to be a pressing need for the development of novel antifungal compounds since there are currently only 13 compounds licensed for the treatment of invasive fungal infections and antibiotic-resistant strains have been emerging. CAY-1 is an antifungal steroidal saponin which was isolated from the fruit of the cayenne pepper plant in 0.1% yield. In Vitro studies of CAY-1 have shown it to be an effective antifungal agent against sixteen pathogenic fungal strains and it showed no cytotoxicity tow
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Books on the topic "Spirostan saponin"

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(Editor), Viqar Uddin Ahmad, and Anwer Basha (Editor), eds. Spectroscopic Data of Steroid Glycosides: Spirostanes, Bufanolides, Cardenolides: Volume 3. Springer, 2007.

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Book chapters on the topic "Spirostan saponin"

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"Schidigera-Saponin A3." In Spectroscopic Data of Steroid Glycosides: Spirostanes, Bufanolides, Cardenolides. Springer US, 2006. http://dx.doi.org/10.1007/978-0-387-39574-6_112.

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"Schidigera-Saponin A1." In Spectroscopic Data of Steroid Glycosides: Spirostanes, Bufanolides, Cardenolides. Springer US, 2006. http://dx.doi.org/10.1007/978-0-387-39574-6_22.

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"Schidigera-Saponin A2." In Spectroscopic Data of Steroid Glycosides: Spirostanes, Bufanolides, Cardenolides. Springer US, 2006. http://dx.doi.org/10.1007/978-0-387-39574-6_23.

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"Zingiberensis Saponin I." In Spectroscopic Data of Steroid Glycosides: Spirostanes, Bufanolides, Cardenolides. Springer US, 2006. http://dx.doi.org/10.1007/978-0-387-39574-6_253.

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"Agave Attenuata Saponin." In Spectroscopic Data of Steroid Glycosides: Spirostanes, Bufanolides, Cardenolides. Springer US, 2006. http://dx.doi.org/10.1007/978-0-387-39574-6_400.

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"Schidigera-Saponin B1." In Spectroscopic Data of Steroid Glycosides: Spirostanes, Bufanolides, Cardenolides. Springer US, 2006. http://dx.doi.org/10.1007/978-0-387-39574-6_64.

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"Schidigera-Saponin C1." In Spectroscopic Data of Steroid Glycosides: Spirostanes, Bufanolides, Cardenolides. Springer US, 2006. http://dx.doi.org/10.1007/978-0-387-39574-6_79.

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"Ornithogalum Thyrsoides Saponin 13." In Spectroscopic Data of Steroid Glycosides: Spirostanes, Bufanolides, Cardenolides. Springer US, 2006. http://dx.doi.org/10.1007/978-0-387-39574-6_1.

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"Reineckia Carnea Saponin 1." In Spectroscopic Data of Steroid Glycosides: Spirostanes, Bufanolides, Cardenolides. Springer US, 2006. http://dx.doi.org/10.1007/978-0-387-39574-6_10.

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"Dioscorea Deltoidea Saponin 1." In Spectroscopic Data of Steroid Glycosides: Spirostanes, Bufanolides, Cardenolides. Springer US, 2006. http://dx.doi.org/10.1007/978-0-387-39574-6_100.

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Conference papers on the topic "Spirostan saponin"

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Lee, CL, JC Yang, CY Peng, and YC Wu. "Anti-metastatic and anti-allergic spirostanol saponins from Solanum macaonense and S. torvum." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608067.

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