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Journal articles on the topic 'Spontaneous Bleeding'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Henriksson, Anders E., and David Bergqvist. "Spontaneous Pancreatic Bleeding." World Journal of Surgery 27, no. 2 (2003): 187–89. http://dx.doi.org/10.1007/s00268-002-6352-2.

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2

Moon, J. M., S. C. Lee, and B. J. Chun. "Spontaneous intercostal artery bleeding." Emergency Medicine Journal 25, no. 1 (2008): 53–54. http://dx.doi.org/10.1136/emj.2007.052548.

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3

Broughan, Thomas A., and Eric M. Walser. "Spontaneous Hepatic Hemorrhage in Older Women." American Surgeon 73, no. 11 (2007): 1147–50. http://dx.doi.org/10.1177/000313480707301115.

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Spontaneous liver hemorrhage in older women is not well described. We report an experience with five postmenopausal women who spontaneously bled from the liver. All five patients presented with acute bleeding. Four were treated nonoperatively. No tumor was identified in any patient. Four patients acutely were discharged alive and well, but one died after operation to control bleeding. Spontaneous liver hemorrhage can occur in a variety of clinical settings, but an association with older women taking hormone replacement and anticoagulation has not been reported.

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Ho-Tin-Noé, B., and S. Jadoui. "Spontaneous bleeding in thrombocytopenia: Is it really spontaneous?" Transfusion Clinique et Biologique 25, no. 3 (2018): 210–16. http://dx.doi.org/10.1016/j.tracli.2018.06.005.

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5

Meyer, F., C. Wybranski, C. J. Bruns, O. Jannasch, V. Aumann, and C. Chiapponi. "Spontaneous omental bleeding in a 20-year old patient with hemophilia A." Hämostaseologie 36, S 02 (2016): S22—S24. http://dx.doi.org/10.5482/hamo-15-01-0003.

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SummarySpontaneous intraabdominal hemorrhage is a very rare event even in patients with bleeding disorders like hemophilia. Nevertheless this rare case must be considered in patients with coagulopathies presenting with abdominal pain. Prompt radiologic imaging and surgical consultation are of highest priority. Here we report on a 20-year-old patient with moderate hemophilia A, who underwent emergency laparotomy for a spontaneous idiopathic bleeding of the omentum majus. There are few cases in the literature on this sort of event in patients with hemophilia, who mostly suffer from spontaneous j

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6

Yen, Chu Yu, and Chun-Chen Chen. "Spontaneous bleeding from orbital haemangioma in drug-induced thrombocytopaenia." BMJ Case Reports 14, no. 7 (2021): e241741. http://dx.doi.org/10.1136/bcr-2021-241741.

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An 81-year-old woman, a drug-induced thrombocytopaenia (DITP) patient, presented with a case of spontaneous bleeding from an orbital haemangioma manifesting as a sudden onset of ocular pain, proptosis and limited eye movement. Image studies revealed an extraconal, cystic lesion with haemorrhage. The ophthalmopathy was caused by the bleeding of the orbital haemangioma and it was resolved after embolisation of the feeding vessels. Spontaneous bleeding of orbital haemangioma is rare. This case emphasises that DITP may be the cause of spontaneous bleeding of orbital haemangioma by precipitating th

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Akyüz, Osman, Müslüm Ergün, Naile Dölek, and Kamil Çam. "Spontaneous severe retroperitoneal hemorrhage with concomitant renal pelvis rupture during the course of COVID-19 infection: a case report." Yeni Üroloji Dergisi 17, no. 2 (2022): 98–103. http://dx.doi.org/10.33719/yud.2022;17-2-1026408.

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Spontaneous rupture of the renal pelvis is a rarely encountered urological event that causes extravasation of urine. It often occurs as a result of increased intrapelvic pressure secondary to obstructions developed in the urinary system. Similarly spontaneous retroperitoneal hematoma is retroperitoneal hemorrhage that occurs without trauma or an underlying pathology. In this study, we present a case of spontaneous rupture of the renal pelvis that developed secondary to compression of the hematoma that occurred spontaneously in the retroperitoneum in a 63-year-old female patient who received an

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8

Solomon, D. J. "Spontaneous subcapsular renal haematoma." South African Journal of Radiology 4, no. 2 (2000): 18–20. http://dx.doi.org/10.4102/sajr.v4i2.1528.

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Spontaneous subcapsular renal haematoma is a rare condition caused by bleeding into the subcapsular or perinephric space in the absence of trauma, bleeding diathesis or anticoagulation. If the contralateral kidney is normal, radical nephrectomy is recommended due to a high incidence of small occult tumours.

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9

Talapatra, Avraneel, Michael J. Nash, Charles R. M. Hay, and Jecko Thachil. "Acquired haemophilia: an easy diagnosis to miss in a patient taking warfarin." Acute Medicine Journal 14, no. 3 (2015): 122–24. http://dx.doi.org/10.52964/amja.0447.

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Acquired Haemophilia (AH) is an autoimmune bleeding disorder, which despite being rare, can be fatal. It occurs in patients with previously normal haemostasis who spontaneously develop IgG autoantibodies against factor VIII. Unlike congenital haemophilia, it manifests as spontaneous bleeding into skin and soft tissues. The presentation can be masked in patients who are receiving warfarin where the bleeding is often attributed to warfarin therapy, as in the case described in this report. Consideration of AH is important in patients taking anticoagulants, when coagulopathy and bleeding fails to

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10

Kuwayama, Naoya, Shinichiro Takahashi, Makoto Sonobe, and Kyoichi Sugita. "Spontaneous bilateral extradural hematomas." Journal of Neurosurgery 62, no. 1 (1985): 139–41. http://dx.doi.org/10.3171/jns.1985.62.1.0139.

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✓ Spontaneous extradural hematomas are rare and may be caused by pericranial infections, bleeding tendencies, or vascular abnormalities of the dura mater. The authors describe a case of spontaneous bilateral extradural hematomas assumed to be caused by a bleeding tendency with hypofibrinogenemia. A brief review of the literature is reported.

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11

Salem, A., S. Healy, and H. Pau. "Management of spontaneous tonsillar bleeding: review." Journal of Laryngology & Otology 124, no. 5 (2010): 470–73. http://dx.doi.org/10.1017/s0022215109992696.

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AbstractObjective:To formulate a management plan for spontaneous tonsillar bleeding.Method:A Medline search was performed and all literature reviewed.Results:Seventeen publications were identified worldwide, describing 55 cases of spontaneous tonsillar bleeding.Conclusion:Although spontaneous tonsillar bleeding is a rare presentation, it is documented in the literature. Reported cases indicate an increased incidence in young patients, associated with a higher mortality rate. We propose a management plan for this potentially fatal condition.

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12

Reid, TD, and WG Sheridan. "Spontaneous omental haematoma – clinical image." Annals of The Royal College of Surgeons of England 92, no. 4 (2010): e38-e38. http://dx.doi.org/10.1308/147870810x12659688852310.

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A case report of spontaneous omental bleeding attributed to a combination of vigorous abdominal exercise and antiplatelet agents. This case serves to high-light the bleeding risks associated with antiplatelet therapy.

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13

Guttilla, Andrea, Alessandro Crestani, Francesco Cattaneo, et al. "Wunderlich’s syndrome: Three cases of acute spontaneous renal bleeding, conservately treated." Archivio Italiano di Urologia e Andrologia 85, no. 4 (2013): 210. http://dx.doi.org/10.4081/aiua.2013.4.210.

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Wunderlich’s syndrome is a clinical condition defined as a spontaneous renal bleeding of non traumatic origin, contained within the Gerota’s fascia. Wunderlich’s syndrome is rare. Spontaneous bleeding of kidney tumors, either benign or malignant, represents the more common causes. Classically it presents with acute flank pain, tender palpable mass and clinical hemodynamic deterioration. These symptoms are defined as the Lenk’s classic triad. We present three cases of spontaneous renal bleeding.

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14

Khoury, Johad, Elias Andrawus, Boaz Y. Bishop, and Zaher S. Azzam. "Unexpected bleeding after Exenatide treatment: a causative relationship or a coincidence?" Endocrine Regulations 52, no. 3 (2018): 159–62. http://dx.doi.org/10.2478/enr-2018-0020.

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AbstractObjectives. Diabetes mellitus is an endemic disease of the current era. It is important to treat it properly. All antidiabetic medications have side effects and various safety profiles.Case report. Fifty-two years old patient with type II diabetes mellitus, who had spontaneous cutaneous and intra muscular bleeding after starting treatment with Exenatide. The patient’s history did not include any kind of spontaneous bleeding. Investigations did not reveal abnormal platelets count and function or coagulation profile. The use of the Exenatide was discontinued and during one year of follow

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15

Chuliber, Fernando, Natalia Paola Schutz, Victoria Otero, et al. "Acquired Factor XIII Deficiency in the Inpatient Setting: Clinical Suspicion, Impact and Treatment: Retrospective Case Series." Blood 128, no. 22 (2016): 1415. http://dx.doi.org/10.1182/blood.v128.22.1415.1415.

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Abstract Introduction: Activated factor XIII (FXIII) stabilizes fibrin clots at the end of the coagulation cascade by bridging fibrin molecules. Disproportionate surgery related bleeding has been reported in association with FXIII deficiency, in patients with normal coagulopathies screening tests, and without a history of previous bleedings. Methods: Retrospective case series. We performed immunological factor XIIIA (FXIIIA) studies in the inpatient setting of the Hospital Italiano de Buenos Aires, between January 2014 and March 2016. FXIIIA below 50% were considered deficient. Patients with s

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16

Swary, Angela Dinaria Kemala, Mia Ratwita Andarsini, and Arifoel Hajat. "Characteristic of Hemophilia A Patients in Initial Diagnosis in Dr. Soetomo General Hospital Surabaya." Biomolecular and Health Science Journal 2, no. 1 (2019): 9. http://dx.doi.org/10.20473/bhsj.v2i1.12888.

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Introduction: This research is conducted to describe the characteristic of Hemophilia A patients.Methods: Cross-sectional study conducted in 55 patients with Hemophilia A. The variables were age, bleeding episode, factor VIII level, and bleeding site. The data presented descriptively.Results: The largest group was 2-10 years old (52,73%). The most common bleeding episode occured in the patients was moderate level (60,0%). The most common patient’s factor VIII level was moderate level (52,7%). The patient’s bleeding most likely took place in muscle or known as hematoma (41,8%). While the less l

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17

Lin, C. Y., Y. H. Lin, F. Z. Wu, and H. B. Pan. "Wunderlich's syndrome in spontaneous angiomyolipoma bleeding." Clinical Kidney Journal 4, no. 3 (2011): 211–12. http://dx.doi.org/10.1093/ndtplus/sfr005.

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18

BARBOSA, JOYCE, JOSÉ ALEXANDRE DA ROCHA CURVELO, VALDIR MEIRELLES, et al. "SPONTANEOUS DORSUM LINGUAL BLEEDING: WHICH CAUSE?" Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 129, no. 1 (2020): e112. http://dx.doi.org/10.1016/j.oooo.2019.06.479.

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19

Shivbalan, So, K. Anandnathan, S. Balasubramanian, Manjula Datta, and Edwin Amalraj. "Predictors of spontaneous bleeding in Dengue." Indian Journal of Pediatrics 71, no. 1 (2004): 33–36. http://dx.doi.org/10.1007/bf02725653.

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20

Bent, Stephen, Harley Goldberg, Amy Padula, and Andrew L. Avins. "Spontaneous bleeding associated with Ginkgo biloba." Journal of General Internal Medicine 20, no. 7 (2005): 657–61. http://dx.doi.org/10.1007/s11606-005-0114-4.

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21

Dick, J. A., K. G. Brame, and W. J. Owen. "Spontaneous bleeding into a parathyroid cyst." British Journal of Surgery 72, no. 9 (1985): 693. http://dx.doi.org/10.1002/bjs.1800720907.

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22

Levy-Mendelovich, Sarina, Tami Brutman-Barazani, Ivan Budnik, et al. "Real-World Data on Bleeding Patterns of Hemophilia A Patients Treated with Emicizumab." Journal of Clinical Medicine 10, no. 19 (2021): 4303. http://dx.doi.org/10.3390/jcm10194303.

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Emicizumab (Hemlibra™) is approved for prophylaxis of hemophilia A (HA) patients. The HAVEN studies addressed bleeding reduction in emicizumab-treated patients, but real-world data on bleeding patterns during emicizumab therapy are lacking. We aimed to compare the occurrence of breakthrough bleeding at different time points, starting from emicizumab initiation. This longitudinal prospective observational cohort study included HA patients (n = 70, aged 1 month to 74.9 years) that completed at least 18 months of follow-up in our center. We analyzed the number of spontaneous and traumatic bleeds

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23

Andreeva, T. A., V. Yu Zorenko, I. L. Davydkin, et al. "Efficacy and safety of the drug Octofactor in prophylactic treatment in patients with severe haemophilia A." Russian Journal of Children Hematology and Oncology 5, no. 3 (2018): 60–73. http://dx.doi.org/10.17650/2311-1267-2018-5-3-60-73.

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Relevance.The development of a new recombinant blood coagulation factor VIII preparation is a promising step towards optimizing the treatment of hemophilia A. An introduction of a new medication into clinical practice precedes a clinical trials to evaluate the efficacy and safety.Materials and methods.The efficacy and safety of the domestic recombinant B-domain deleted blood coagulation factor VIII (FVIII) (moroctocog alfa, Octofactor®, JSC “GENERIUM”) were studied in the preventive treatment of 31 patients aged 21 to 52 years with severe haemophilia A. The Octofactor was administered in doses

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24

Shi, Qizhen, Jeremy G. Mattson, Scot A. Fahs, Aron M. Geurts, Hartmut Weiler, and Robert R. Montgomery. "The severe spontaneous bleeding phenotype in a novel hemophilia A rat model is rescued by platelet FVIII expression." Blood Advances 4, no. 1 (2020): 55–65. http://dx.doi.org/10.1182/bloodadvances.2019000944.

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Key Points A novel HA rat model caused by an inversion exhibits a severe spontaneous bleeding phenotype. The severe spontaneous bleeding phenotype in HA rats is rescued by platelet-targeted FVIII expression.

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25

Canbilen, Sefa William, Khaldoun El Abed, and Riaz Ahmad. "Spontaneous atraumatic knee haemarthrosis." BMJ Case Reports 13, no. 10 (2020): e236362. http://dx.doi.org/10.1136/bcr-2020-236362.

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Spontaneous knee haemarthrosis is a rare condition, most prevalent in the elderly with osteoarthritis. Recent reports have proposed that the source of bleeding is the peripheral arteries supplying the posterior horn of the lateral meniscus. In this case, a 62-year-old active man presented with acute postero-lateral left knee pain and swelling with limited weight bearing or movement of the knee. No recent history of trauma but history of lateral compartment dominant osteoarthritis and arthroscopic partial lateral meniscectomy of left knee. Aspiration showed a large haemarthrosis and following a

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26

Zapletal, Ondrej, Jan Blatny, Roman Kotlin та Jan E. Dyr. "Severe Spontaneous Intracranial Bleeding in 11 Months Old Boy with Congenital Afibrinogenemia with Novel Mutation - Deletion aα 6477A in Fibrinogen Gene". Blood 124, № 21 (2014): 5070. http://dx.doi.org/10.1182/blood.v124.21.5070.5070.

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Abstract Congenital afibrinogenemia is very rare inherited bleeding disorder, caused by absence of fibrinogen in plasma. Serious spontaneous bleeding including intracranial haemorrhage may occur at any age. We present a case report of a boy with afibrinogenemia caused by novel mutation – homozygous deletion Aα 6477A. Diagnosis was set after bleeding post cleft lip and palate plastic surgery. Spontaneous intracranial haematoma in occipital region occurred when the boy was 11 month old. Replacement therapy with plasma derived fibrinogen concentrate successfully covered neurosurgical evacuation o

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27

Ohn, May Honey, Jun Rong Ng, Ng Pey Luen, and Khin Maung Ohn. "Atypical presentation of catastophric spontaneous mesenteric bleeding." BMJ Case Reports 14, no. 8 (2021): e244051. http://dx.doi.org/10.1136/bcr-2021-244051.

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Spontaneous mesenteric bleeding is an exceptionally rare clinical condition and potentially lethal especially among elderly patients who are taking oral anticoagulant. We present a case of a 79-year-old woman who presented to the emergency department with atypical chest pain which was radiating to the back. She developed profound hypotension with a sudden drop of haemoglobin. Contrast-enhanced CT of the aorta showed active mesenteric bleeding with mesenteric haematoma. The early diagnosis relies solely on a high index of suspicion of occult bleeding in patients with unexplained hypotension wit

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Lima, Telmo Tiburcio Fortes, Mirto Nelso Prandini, Pasquale Gallo, and Sérgio Cavalheiro. "Prognostic Value of Intraventricular Bleeding in Spontaneous Intraparenchymal Cerebral Hemorrhage of Small Volume: A Prospective Cohort Study." Neurosurgery 70, no. 4 (2011): 929–35. http://dx.doi.org/10.1227/neu.0b013e31823bcc42.

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Abstract BACKGROUND: The literature is controversial on whether intraventricular bleeding has a negative impact on the prognosis of spontaneous intracerebral hemorrhage. Nevertheless, an association between intraventricular bleeding and spontaneous intracerebral hemorrhage volumes has been consistently reported. OBJECTIVE: To evaluate the prognostic value of intraventricular bleeding in deep intraparenchymal hypertensive spontaneous hemorrhage with a bleeding volume &lt;30 cm3. METHODS: Of the 320 patients initially evaluated, 33 met the inclusion criteria and were enrolled in this prospec

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Contreras-Jodar, Alexandra, Aranzazu Varvaró-Porter, Antonio Velarde, and Virginie Michel. "Relevant Indicators of Consciousness after Waterbath Stunning in Turkeys and Stunning Efficiency in Commercial Conditions." Animals 13, no. 4 (2023): 668. http://dx.doi.org/10.3390/ani13040668.

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The prevalence and inter-observer repeatability of the four most valid and feasible indicators of consciousness after waterbath stunning in turkeys were evaluated before bleeding (i.e., tonic convulsion, breathing, spontaneous blinking and vocalization) and during bleeding (i.e., fluttering, breathing, spontaneous swallowing and head shaking). Furthermore, correlations between them were calculated to further understand the association between such indicators. This study compared the assessments of four observers on 7877 turkeys from 28 flocks slaughtered in eight different abattoirs. Repeatabi

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Kudratovna, Askarova Fotima, and Yakhshinorov Islombek Nodirjonovich. "VAGINAL BLEEDING IN EARLY PREGNANCY." International Journal of Medical Sciences And Clinical Research 4, no. 3 (2024): 16–20. http://dx.doi.org/10.37547/ijmscr/volume04issue03-03.

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Bleeding is a common complication of pregnancy, with 10-15% of women reporting some bleeding during the first sixteen weeks of pregnancy (Ananth and Savitz 1994). In general, bleeding is considered arisk factor for adverse fetal outcomes, including spontaneous abortion, preterm birth and low birth weight (Batzorn et al. 1984). However, recall bias may explain some of these findings. In addition, Moreover, the timing of bleeding is difficult to determine retrospectively, and studies sometimes group all bleeding during one trimester or half trimester of pregnancy (Ananth and Savitz 1994; Everett

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Francesco, Vincenzo De, Franca Castellucci, Silverio Balzano, and Angelo Zullo. "An unusual case of hematemesis: Spontaneous reno-duodenal fistula." Journal of Digestive Endoscopy 05, no. 01 (2014): 037–38. http://dx.doi.org/10.4103/0976-5042.141936.

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AbstractDifferent diseases may cause gastrointestinal bleeding. A fistula infrequently manifest with severe intestinal bleeding, when excluding those directly involving vascular structures. We described a case of upper digestive bleeding by a spontaneous renal-duodenal fistula in the patient with kidney cancer. Bleeding was successfully stopped by transarterial embolization.

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Tripathi, Preeti, H. P. Pati, Seema Tyagi, M. Mahapatra, Ankur Ahuja, and Renu Saxena. "Amyloidosis Presenting as Severe Bleeding Diathesis." International Journal of Medical and Dental Sciences 6, no. 2 (2017): 1535. http://dx.doi.org/10.18311/ijmds/2017/18846.

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Bleeding is one of the rare presentations of Amyloidosis. The mechanism behind spontaneous or peri- interventional bleeding in patients of amyloidosis is complex and involves multiple co-existing factors like coagulation factor deficiency, abnormal synthesis of coagulation factors due to advanced liver dysfunction, acquired Von Willebrand disease, platelet dysfunction, amyloid angiopathy and other unknown mechanisms. We present a case of middle aged female, presenting with spontaneous retroperitoneal haemorrhage, on further investigations was found to have systemic amyloidosis and secondary se

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Ahmed, Sagir G., Umma A. Ibrahim, Modu B. Kagu, and Usman A. Abjah. "Does sickle cell trait reduce the frequency of spontaneous bleeds in severe haemophilia?" Journal of Haemophilia Practice 3, no. 2 (2016): 50–54. http://dx.doi.org/10.17225/jhp00083.

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Abstract Haemophilia A is an X-linked recessive disorder associated with deficiency of coagulation factor VIII and lifelong bleeding diathesis. Sickle cell trait (SCT) is the heterozygous state for the sickle β-globin gene. The frequency of SCT is up to 30% in Africa, wherein it confers survival advantage by providing resistance against severe malaria. SCT does not cause vaso-occlusive crisis, but is associated with high risk of venous thromboembolism as variously reported in the literature. We consider SCT as a hypercoagulable prothrombotic state and hypothesise that coinheritance of SCT may

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34

Bhandari, R. S., R. Sapkota, P. Mishra, and K. P. Singh. "Spontaneous omental hematoma." Journal of Institute of Medicine Nepal 31, no. 1 (2009): 20–22. http://dx.doi.org/10.59779/jiomnepal.371.

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Spontaneous omental bleeding is a rare entity, and usually presents with various combination of sudden abdominal pain, shock, peritonitis and hemoperitoneum. A 68 year female presenting with acute abdomen and without antecedent trauma had obscure hemoperitoneum. Exploration revealed hemoperitoneum and hemorrhagic omentum with a huge clot.

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Tokgoz, Huseyin, Umran Caliskan, Akar Nejat, and Erdem Ak. "Mutation Analysis and Clinical Sprectrum Of Patients With Glanzmann’s Thrombasthenia and Bernard Soulier Syndrome." Blood 122, no. 21 (2013): 4751. http://dx.doi.org/10.1182/blood.v122.21.4751.4751.

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Introduction and Aim Glanzmann’s thrombasthenia (GT) is an inherited disorder of platelet aggregation, resulting from defective glycoprotein IIb/IIIa on platelet surface. Bernard Soulier Syndrome (BSS) is also an inherited disorder of platelet adhesion and associated with defective glycoprotein Ib-V-IX on platelet surface. Both of these disorders usually present with mucocutaneous bleedings. We aimed to evaluate the clinical and genetic characteristics of the patients diagnosed as BSS and GT in department of pediatric hematology of Meram Faculty of Medicine, retrospectively. Method Seven patie

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Sumarokov, A. B., L. I. Buryachkovskaya, and N. V. Lomakin. "Specific Antidotes for Direct Oral Anticoagulants in Life-Threatening Bleeding." Rational Pharmacotherapy in Cardiology 14, no. 6 (2019): 944–50. http://dx.doi.org/10.20996/1819-6446-2018-14-6-944-950.

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Review presents data on medicines from the new group of cardiovascular drugs, direct oral anticoagulants (DOACs) inhibitors, as antidotes for DOAC when stopping life-threatening bleeding. DOAC therapy is accorded by hemorrhages with lower frequency than therapy by indirect anticoagulants, but really exist. New antidotes for DOACs are idarucizumab, andexanet, ciraparantag. The need in antidotes for DOAC may suddenly appear in spontaneous bleeding, during surgical operation, invasive procedure, due to trauma, in patients with stroke, kidney or liver failure. Data is given on the frequency of the

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Watanabe, Yukinobu, Naoki Matsumoto, Masahiro Ogawa, Mitsuhiko Moriyama, and Masahiko Sugitani. "Sarcomatoid Hepatocellular Carcinoma with Spontaneous Intraperitoneal Bleeding." Internal Medicine 54, no. 13 (2015): 1613–17. http://dx.doi.org/10.2169/internalmedicine.54.3523.

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38

Konja, Blanka Glavaš, Ivan Bitunjac, Zvonimir Ostojić, et al. "Spontaneous bleeding during ticagrelor therapy – case report." Cardiologia Croatica 11, no. 10-11 (2016): 445. http://dx.doi.org/10.15836/ccar2016.445.

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39

PRICE, A. "SPONTANEOUS NON-GASTROINTESTINAL BLEEDING ASSOCIATED WITH DICLOFENAC." Lancet 334, no. 8678-8679 (1989): 1520. http://dx.doi.org/10.1016/s0140-6736(89)92958-9.

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40

Ahmad, Jawad, Beata Lakomiec, and Maurice B. Loughrey. "Spontaneous Adult Intussusception Presenting as Rectal Bleeding." Clinical Gastroenterology and Hepatology 9, no. 2 (2011): A18. http://dx.doi.org/10.1016/j.cgh.2010.08.003.

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Islam, Mahibul, Pranjal Deka, Raj Kapur, and Md AbuMasud Ansari. "Non-bleeding spontaneous rupture of hepatocellular carcinoma." Nigerian Journal of Surgery 19, no. 2 (2013): 82. http://dx.doi.org/10.4103/1117-6806.119241.

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42

Contreras-Jodar, Alexandra, Aranzazu Varvaró-Porter, Virginie Michel, and Antonio Velarde. "Inter-Observer Repeatability of Indicators of Consciousness after Waterbath Stunning in Broiler Chickens." Animals 12, no. 14 (2022): 1800. http://dx.doi.org/10.3390/ani12141800.

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This study evaluated the prevalence and tested the inter-observer repeatability of the most valid and feasible animal-based indicators of the state of consciousness after waterbath stunning in broilers before bleeding (tonic seizure, breathing, spontaneous blinking and vocalization) and during bleeding (wing flapping, breathing, spontaneous swallowing and head shaking). In addition, correlations among them were computed to better understand their relationship and offer insights into the reliability of such indicators. This was aimed at proposing a refined list of indicators that could be used

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Vazzana, Natale, Luca Scarti, Chiara Beltrame, Antonella Picchi, Gianni Taccetti, and Alberto Fortini. "Acquired Factor XI Inhibitor Presenting as Spontaneous Bilateral Subdural Hematoma in an Elderly Patient." Case Reports in Hematology 2014 (2014): 1–4. http://dx.doi.org/10.1155/2014/626831.

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Development of autoantibodies against coagulation factors is an uncommon bleeding disorder associated with cancer, autoimmune conditions, pregnancy, or no apparent disease. Spontaneous FVIII inhibitors are the most frequently encountered; those against FXI have been only anecdotally reported. We report a case of acquired FXI inhibitor presenting as fatal intracranial spontaneous bleeding in an elderly patient with history of cancer and previous transfusions. Few cases of acquired FXI inhibitor have been reported in association with connective tissue disease, cancer, or surgery. Bleeding includ

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Triulzi, Darrell J. "How well do platelets prevent bleeding?" Hematology 2020, no. 1 (2020): 518–22. http://dx.doi.org/10.1182/hematology.2020000136.

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Abstract Prophylactic platelet transfusions are used to reduce the risk of spontaneous bleeding in patients with treatment- or disease-related severe thrombocytopenia. A prophylactic platelet-transfusion threshold of &lt;10 × 103/µL has been shown to be safe in stable hematology/oncology patients. A higher threshold and/or larger or more frequent platelet doses may be appropriate for patients with clinical features associated with an increased risk of bleeding such as high fevers, sepsis, disseminated intravascular coagulation, anticoagulation therapy, or splenomegaly. Unique factors in th

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Sedik, Alaa, Meriem Touheria, Ahmed Fathi, et al. "Spontaneous rupture of the pancreatic pseudocyst into the duodenum with massive upper gastrointestinal bleeding: case report and literature review." International Surgery Journal 7, no. 11 (2020): 3792. http://dx.doi.org/10.18203/2349-2902.isj20204694.

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Pancreatic pseudocyst is one of the common complications of both acute and chronic pancreatitis. While most pseudocysts resolve spontaneously with conservative treatment, larger pseudocysts are more likely to cause complications, such as, spontaneous rupture into the gastrointestinal tract and are usually associated with life-threatening bleeding, which is life threatening complication. Endoscopic or surgical drainage may be necessary for uncomplicated persistent large cysts. We present a case of 32 year old Indian male, admitted to our department, who was a known case of alcoholic acute pancr

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Kim, Seung-Hyun, Ho-Jun Lee, Dong-Wan Kim, Jun-Ho Choi, Jae-Ha Hwang, and Kwang-Seog Kim. "Spontaneous Chest Wall Hematoma in a Hemodialysis Patient: A Case Report." Journal of Clinical Medicine 14, no. 2 (2025): 396. https://doi.org/10.3390/jcm14020396.

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Background/Objectives: Spontaneous chest wall hematomas are rare but potentially life-threatening complications, particularly in patients with multiple comorbidities such as those undergoing hemodialysis. This case report aims to highlight the significance of early diagnosis and appropriate management in preventing complications associated with this condition. Methods: We report the case of a 79-year-old man with end-stage renal disease on hemodialysis, presenting with a large spontaneous hematoma (18.7 × 13.1 × 9.6 cm) in the right upper chest wall. Initial interventions, including diagnostic

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Ghifary, Faathir Baihaqi, and Tanaya Ghinorawa. "Spontaneous retrovesical bleeding on COVID-19 patient: A rare case." Indonesia Journal of Biomedical Science 18, no. 1 (2024): 37–40. http://dx.doi.org/10.15562/ijbs.v18i1.530.

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Introduction: COVID-19 does not merely cause respiratory distress as a clinical manifestation but also can develop into other systemic conditions such as cardiovascular, neurologic, hematopoietic, coagulopathy, and immunity disorders, and finally, multiple organ failure. This case aims to report a rare case of spontaneous retrovesical bleeding as one of the complications of COVID-19 Case Description: The patient was a female 66 years old with COVID-19 who complained of abdominal mass, followed by abdominal pain, decrease of consciousness, and unstable hemodynamics. During exploratory laparotom

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Mishra, Shivani, Madhu Singh Ratre, and Parul Jain. "Spontaneous postoperative bleeding after periodontal procedure: An alarming sign of bleeding disorder." Journal of Indian Society of Periodontology 28, no. 2 (2024): 258–61. http://dx.doi.org/10.4103/jisp.jisp_308_23.

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Abstract The prevalence of inherited bleeding disorders (BDs) is low in the general population (10–20 per 100,000 individuals), particularly hemophilia B cases, which may remain undiagnosed for a very long time until exposed to some surgical procedure. The dental professional must be aware of the possibility that patients with no previous history of abnormal bleeding may manifest their first bleeding episode in the dental office. Particularly as periodontists, we often encounter patients with bleeding gums and severe bleeding complications may precipitate while performing routine periodontal p

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Wei, Huijun, Jin Shang, CarolAnn Keohane, et al. "A novel approach to assess the spontaneous gastrointestinal bleeding risk of antithrombotic agents using Apc min/+ mice." Thrombosis and Haemostasis 111, no. 06 (2014): 1121–32. http://dx.doi.org/10.1160/th13-11-0926.

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SummaryAssessment of the bleeding risk of antithrombotic agents is usually performed in healthy animals with some form of vascular injury to peripheral organs to induce bleeding. However, bleeding observed in patients with currently marketed antithrombotic drugs is typically spontaneous in nature such as intracranial haemorrhage (ICH) and gastrointestinal (GI) bleeding, which happens most frequently on top of preexisting pathologies such as GI ulcerations and polyps. Apc min/+ mice are reported to develop multiple adenomas through the entire intestinal tract and display progressive anaemia. In

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Amatya, Elina, Romano Fois, Kylie A. Williams, and Lisa G. Pont. "Potential for Detection of Safety Signals for Over-the-Counter Medicines Using National ADR Spontaneous Reporting Data: The Example of OTC NSAID-Associated Gastrointestinal Bleeding." Pharmacy 8, no. 3 (2020): 174. http://dx.doi.org/10.3390/pharmacy8030174.

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One post-marketing surveillance challenge for many regulatory authorities is access to information regarding the safety of over-the-counter (OTC) medicines. National spontaneous adverse drug reaction (ADR) report data represent a rich potential data source for the detection of safety signals associated with OTC medicines, yet little is known regarding the possibility of detecting safety signals for OTC medicines within these datasets. The aim of this study was to evaluate the potential for detecting safety signals for OTC medicines in National ADR spontaneous reporting data, using OTC non-ster

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