Academic literature on the topic 'Spontaneous intracranial bleeding'
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Journal articles on the topic "Spontaneous intracranial bleeding"
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Zapletal, Ondrej, Jan Blatny, Roman Kotlin, and Jan E. Dyr. "Severe Spontaneous Intracranial Bleeding in 11 Months Old Boy with Congenital Afibrinogenemia with Novel Mutation - Deletion aα 6477A in Fibrinogen Gene." Blood 124, no. 21 (December 6, 2014): 5070. http://dx.doi.org/10.1182/blood.v124.21.5070.5070.
Full textAbstract:
Abstract Congenital afibrinogenemia is very rare inherited bleeding disorder, caused by absence of fibrinogen in plasma. Serious spontaneous bleeding including intracranial haemorrhage may occur at any age. We present a case report of a boy with afibrinogenemia caused by novel mutation – homozygous deletion Aα 6477A. Diagnosis was set after bleeding post cleft lip and palate plastic surgery. Spontaneous intracranial haematoma in occipital region occurred when the boy was 11 month old. Replacement therapy with plasma derived fibrinogen concentrate successfully covered neurosurgical evacuation of hematoma. The patient was then commenced on regular prophylaxis with fibrinogen concentrate two times a week. No further bleeding episodes occurred until present time. Spontaneous intracranial bleeding in patients with inherited bleeding disorders is often life threatening. Immediate replacement therapy is crucial, together with diagnostics and surgery, when necessary. Prophylactic substitution therapy after a severe bleeding episode is recommended. Disclosures No relevant conflicts of interest to declare.
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Quinones-Hinojosa, Alfredo, Mittul Gulati, Vineeta Singh, and Michael T. Lawton. "Spontaneous intracerebral hemorrhage due to coagulation disorders." Neurosurgical Focus 15, no. 4 (October 2003): 1–17. http://dx.doi.org/10.3171/foc.2003.15.4.3.
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Although intracranial hemorrhage accounts for approximately 10 to 15% of all cases of stroke, it is associated with a high mortality rate. Bleeding disorders account for a small but significant risk factor associated with intracranial hemorrhage. In conditions such as hemophilia and acute leukemia associated with thrombocytopenia, massive intracranial hemorrhage is often the cause of death. The authors present a comprehensive review of both the physiology of hemostasis and the pathophysiology underlying spontaneous ICH due to coagulation disorders. These disorders are divided into acquired conditions, including iatrogenic and neoplastic coagulopathies, and congenital problems, including hemophilia and rarer diseases. The authors also discuss clinical features, diagnosis, and management of intracranial hemorrhage resulting from these bleeding disorders.
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Boŝnjak, Róman, Christopher Derham, Mara Popović, and Janez Ravnik. "Spontaneous intracranial meningioma bleeding: clinicopathological features and outcome." Journal of Neurosurgery 103, no. 3 (September 2005): 473–84. http://dx.doi.org/10.3171/jns.2005.103.3.0473.
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Hou, Kun, Xiaobo Zhu, Yang Sun, Xianfeng Gao, Jinchuan Zhao, Yang Zhang, and Guichen Li. "Transient Acute Hydrocephalus After Spontaneous Intracranial Bleeding in Adults." World Neurosurgery 100 (April 2017): 38–43. http://dx.doi.org/10.1016/j.wneu.2016.12.103.
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Ataoglu, Emel, Nilgun S. Duru, Tiraje Celkan, Mahmut Civilibal, Selda C. Yavuz, Murat Elevli, and Semih Ayta. "Spontaneous intracranial bleeding in a neonate with congenital afibrinogenemia." Blood Coagulation & Fibrinolysis 21, no. 6 (September 2010): 592–94. http://dx.doi.org/10.1097/mbc.0b013e32833a06e2.
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Utami, Sri, Muhamad Yunus, and Deviani Utami. "Gambaran Pengetahuan Bidan dan Perawat Tentang VKDB di Puskesmas Prabumulih Sumatera Selatan." ARTERI : Jurnal Ilmu Kesehatan 2, no. 1 (April 1, 2021): 23–29. http://dx.doi.org/10.37148/arteri.v2i1.142.
Full textAbstract:
Intracranial hemorrhage is a dangerous bleeding in infants. The impact of intracranial bleeding is in the form of death and sequelae, such as hydrocephalus, cerebral atrophy, encephalopathy, and epilepsy which will interfere with growth and development. One of the causes of intracranial bleeding is bleeding due to Vitamin K deficiency (VKDB). Meanwhile, intracranial bleeding due to vitamin K deficiency can be prevented by giving vitamin K1 to newborns. This study aimed to know the description of the level of knowledge of health workers about spontaneous intracranial bleeding caused by vitamin K deficiency bleeding at the Prabumulih Health Center, South Sumatra in 2020. The type of research used in this research is descriptive with a cross sectional design. The samples used in this study were nurses and midwives who worked at the Prabumulih Health Center in South Sumatra who had met the criteria in this study. The result showed that the frequency of sufficient knowledge of respondents was found as many as 31 people with a percentage of 46.3%. In conclusion Midwives at the Prabumulih health center in South Sumatra have a sufficient level of knowledge about intracranial bleeding due to vitamin K deficiency. It is hoped that this study can provide information to the public about the knowledge of intracranial bleeding due to vitamin K deficiency, so that the incidence of intracranial bleeding due to vitamin K deficiency and infant mortality can be reduced.
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Calderon-Miranda, Willem Guillermo, Nidia Escobar Hernandez, Luis Rafael Moscote Salazar, and Amit Agrawal. "Acute spontaneous subdural hematomaas unusual complication after tooth extraction." Romanian Neurosurgery 30, no. 3 (September 1, 2016): 397–401. http://dx.doi.org/10.1515/romneu-2016-0061.
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Abstract Background: Intracranial bleeding has been reported in the literature associated with tooth extraction. Coagulation disorders are often associated with complications after dental extraction. In this case report, we describe a case of spontaneously intracranial subdural hematoma possible after tooth extraction. Case description: The patient was a 26-y-old female without any underlying diseases. A computerized tomography scan showed a subdural hematoma 48 hours after the dental extraction. She was managed with a burr hole, good postoperative evolution and discharged to home. Conclusion: Although rare, the presence of headache with signs of alarm after the extraction of a tooth, we must discard intracranial abnormalities. To the best of our knowledge this is the first report in the literature of a spontaneously intracranial subdural hematoma possible after tooth extraction.
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Swary, Angela Dinaria Kemala, Mia Ratwita Andarsini, and Arifoel Hajat. "Characteristic of Hemophilia A Patients in Initial Diagnosis in Dr. Soetomo General Hospital Surabaya." Biomolecular and Health Science Journal 2, no. 1 (June 30, 2019): 9. http://dx.doi.org/10.20473/bhsj.v2i1.12888.
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Introduction: This research is conducted to describe the characteristic of Hemophilia A patients.Methods: Cross-sectional study conducted in 55 patients with Hemophilia A. The variables were age, bleeding episode, factor VIII level, and bleeding site. The data presented descriptively.Results: The largest group was 2-10 years old (52,73%). The most common bleeding episode occured in the patients was moderate level (60,0%). The most common patient’s factor VIII level was moderate level (52,7%). The patient’s bleeding most likely took place in muscle or known as hematoma (41,8%). While the less likely bleeding were intracranial and nose bleeding.Conclusion: 2-10 years old patient are the largest group because of hemophilia A mostly diagnosed in childhood, where children are actively moved so that the spontaneous bleeding or abnormal bleeding can be seen easily. Parents needs to be aware if there were abnormal or spontaneous bleeding which takes place in muscle or known as hematoma with moderate episode of bleeding which meant that the occurrence of spontaneous bleeding is periodically happened or in prolonged bleeding accompanied by minor trauma or invasive action.
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Vazzana, Natale, Luca Scarti, Chiara Beltrame, Antonella Picchi, Gianni Taccetti, and Alberto Fortini. "Acquired Factor XI Inhibitor Presenting as Spontaneous Bilateral Subdural Hematoma in an Elderly Patient." Case Reports in Hematology 2014 (2014): 1–4. http://dx.doi.org/10.1155/2014/626831.
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Development of autoantibodies against coagulation factors is an uncommon bleeding disorder associated with cancer, autoimmune conditions, pregnancy, or no apparent disease. Spontaneous FVIII inhibitors are the most frequently encountered; those against FXI have been only anecdotally reported. We report a case of acquired FXI inhibitor presenting as fatal intracranial spontaneous bleeding in an elderly patient with history of cancer and previous transfusions. Few cases of acquired FXI inhibitor have been reported in association with connective tissue disease, cancer, or surgery. Bleeding includes mucocutaneous bleeding, postsurgical hemorrhage, or life-threatening events. Treatment consists of arresting the bleeding and inhibitor eradication. High degree of suspicion is essential to promptly diagnose and treat this uncommon condition.
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Henriques, José Gilberto de Brito, Geraldo Pianetti Filho, Karina Santos Wandeck Henriques, Luiz Fernando Fonseca, Renato Pacheco de Melo, Márcia Cristina da Silva, and José Augusto Malheiros. "Spontaneous acute subdural hematoma contralateral to an arachnoid cyst." Arquivos de Neuro-Psiquiatria 65, no. 4a (December 2007): 1034–36. http://dx.doi.org/10.1590/s0004-282x2007000600025.
Full textAbstract:
Arachnoid cysts (AC) are extra-cerebral cerebrospinal fluid collections of unknown origin. They correspond to 1% of all intracranial nontraumatic space-occupying lesions and appear more frequently in the middle fossa (50%). More than 25% of these cysts are incidental findings and the majority of patients are asymptomatic. Seizures, intracranial hypertension signs, neurological deficits, macrocrania, developmental delay and bulging of the skull are the main signs and symptoms of the lesion. AC rupture and bleeding are rare, usually occurring in young adults and associated with trauma. The risk of hemorrhage does not exceed 0.04% / year. We describe the case of a ten-year-old boy who presented with acute signs of intracranial hypertension secondary to a spontaneous acute subdural hematoma, contralateral to an AC of the middle fossa. Three factors were significant in this case: signs and symptoms occurred spontaneously; the presence of an acute subdural hematoma exclusively contralateral to the AC; successful outcome of the conservative treatment.
Dissertations / Theses on the topic "Spontaneous intracranial bleeding"
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Haus, Sebastian. "Anisokorie im Schockraum – Prognosefaktoren für das klinische Outcome." Doctoral thesis, 2017. http://hdl.handle.net/11858/00-1735-0000-0023-3E04-7.
Full textBooks on the topic "Spontaneous intracranial bleeding"
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Sharma, Deepak, and Julia Metzner. Nontraumatic Intracranial Hemorrhage. Edited by Matthew D. McEvoy and Cory M. Furse. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190226459.003.0062.
Full textAbstract:
Nontraumatic subarachnoid, intraventricular, or intraparenchymal hemorrhage can be caused by either rupture of an aneurysm or arteriovenous malformation or by coagulopathy, hypertension, or vasculitis. Pituitary apoplexy results from spontaneous hemorrhage or infarction into a pituitary tumor. Additionally, anesthesiologists must be prepared to manage intraoperative bleeding during craniotomies. Successful management of nontraumatic intracranial hemorrhage requires (1) careful preoperative evaluation and preparation considering extracranial manifestations of intracranial bleeding; (2) administration of balanced anesthesia to facilitate surgical exposure and neurophysiological monitoring; (3) maintenance of cerebral perfusion by preserving circulating volume, judicious use of blood product transfusion and vasopressors, and avoidance of excessive hyperventilation; and, when possible, (4) providing timely emergence from anesthesia to allow neurological assessment. Close communication between the surgical and anesthesia teams is critical for optimizing the potential for good patient outcomes.
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Matthew Kynes, J. Hemophilia (Presentation in Emergency Surgery). Edited by Matthew D. McEvoy and Cory M. Furse. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190226459.003.0085.
Full textAbstract:
Hemophilia is a complex disease of variable severity that affects clotting function and has significant implications in perioperative and emergency care. Hereditary or de novo mutations cause deficiencies in factor VIII or IX production, which may manifest as spontaneous bleeding into joint spaces, muscles, or other sites in severe forms of the disease. Intracranial bleeding is one of the most serious and often fatal complications. In a patient with abnormal bleeding, laboratory results indicative of hemophilia include an increased partial prothromboplastin time (PT), with normal prothrombin time/international normalized ratio (PTT/INR) and normal platelet count. The diagnosis is confirmed with specific factor assays. Advances in prophylaxis with factor replacement have improved outcomes and reduced bleeding episodes in hemophilia. However, patients with hemophilia may present emergently for operation and require factor replacement. In patients that have developed antibodies to factor replacement, clotting factor bypass agents may be required to control bleeding.
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Leys, Didier, Charlotte Cordonnier, and Valeria Caso. Stroke. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199687039.003.0067_update_002.
Full textAbstract:
Stroke is a major public health issue. Many are treatable in the acute stage, provided patients are admitted soon enough. The overall incidence of stroke in Western countries is approximately 2400 per year per million inhabitants, and 80% are due to cerebral ischaemia. The prevalence is approximately 12 000 per million inhabitants. Stroke is associated with increased long-term mortality, handicap, cognitive and behavioural impairments, recurrence, and an increased risk of other types of vascular events. It is of major interest to take the heterogeneity of stroke into account, because of differences in the acute management, secondary prevention, and outcomes, according to the subtype and cause of stroke. In all types of stroke, early epileptic seizures, delirium, increased intracranial pressure, and non-specific complications are frequent. In ischaemic strokes, specific complications, such as malignant infarcts, spontaneous haemorrhagic transformation, early recurrence, and a new ischaemic event in another vascular territory, are frequent. In haemorrhagic strokes, the major complication is the subsequent increased volume of bleeding. There is strong evidence that stroke patients should be treated in dedicated stroke units; each time 24 patients are treated in a stroke unit, instead of a conventional ward, one death and one dependence are prevented. This effect does not depend on age, severity, and the stroke subtype. For this reason, stroke unit care is the cornerstone of the treatment of stroke, aiming at the detection and management of life-threatening emergencies, stabilization of most physiological parameters, and prevention of early complications. In ischaemic strokes, besides this general management, specific therapies include intravenous recombinant tissue plasminogen activator, given as soon as possible and before 4.5 hours, mechanical thrombectomy in case of proximal occlusion (middle cerebral artery, intracranial internal carotid artery, basilar artery), on top of thrombolysis in the absence of contraindication or alone otherwise, aspirin 300 mg, immediately or after 24 hours in case of thrombolysis, and, in a few patients, decompressive surgery. In intracerebral haemorrhages, blood pressure lowering and haemostatic therapy, when needed, are the two targets, while surgery does not seem effective to reduce death and disability.
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Leys, Didier, Charlotte Cordonnier, and Valeria Caso. Stroke. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199687039.003.0067.
Full textAbstract:
Stroke is a major public health issue. Many are treatable in the acute stage, provided patients are admitted soon enough. The overall incidence of stroke in Western countries is approximately 2400 per year per million inhabitants, and 80% are due to cerebral ischaemia. The prevalence is approximately 12 000 per million inhabitants. Stroke is associated with increased long-term mortality, handicap, cognitive and behavioural impairments, recurrence, and an increased risk of other types of vascular events. It is of major interest to take the heterogeneity of stroke into account, because of differences in the acute management, secondary prevention, and outcomes, according to the subtype and cause of stroke. In all types of stroke, early epileptic seizures, delirium, increased intracranial pressure, and non-specific complications are frequent. In ischaemic strokes, specific complications, such as malignant infarcts, spontaneous haemorrhagic transformation, early recurrence, and a new ischaemic event in another vascular territory, are frequent. In haemorrhagic strokes, the major complication is the subsequent increased volume of bleeding. There is strong evidence that stroke patients should be treated in dedicated stroke units; each time 24 patients are treated in a stroke unit, instead of a conventional ward, one death and one dependence are prevented. This effect does not depend on age, severity, and the stroke subtype. For this reason, stroke unit care is the cornerstone of the treatment of stroke, aiming at the detection and management of life-threatening emergencies, stabilization of most physiological parameters, and prevention of early complications. In ischaemic strokes, besides this general management, specific therapies include intravenous recombinant tissue plasminogen activator, given as soon as possible and before 4.5 hours, otherwise aspirin 300 mg, immediately or after 24 hours in case of thrombolysis, and, in a few patients, decompressive surgery. In intracerebral haemorrhages, blood pressure lowering and haemostatic therapy, when needed, are the two targets, but surgery does not seem effective to reduce death and disability.
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Leys, Didier, Charlotte Cordonnier, and Valeria Caso. Stroke. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199687039.003.0067_update_001.
Full textAbstract:
Stroke is a major public health issue. Many are treatable in the acute stage, provided patients are admitted soon enough. The overall incidence of stroke in Western countries is approximately 2400 per year per million inhabitants, and 80% are due to cerebral ischaemia. The prevalence is approximately 12 000 per million inhabitants. Stroke is associated with increased long-term mortality, handicap, cognitive and behavioural impairments, recurrence, and an increased risk of other types of vascular events. It is of major interest to take the heterogeneity of stroke into account, because of differences in the acute management, secondary prevention, and outcomes, according to the subtype and cause of stroke. In all types of stroke, early epileptic seizures, delirium, increased intracranial pressure, and non-specific complications are frequent. In ischaemic strokes, specific complications, such as malignant infarcts, spontaneous haemorrhagic transformation, early recurrence, and a new ischaemic event in another vascular territory, are frequent. In haemorrhagic strokes, the major complication is the subsequent increased volume of bleeding. There is strong evidence that stroke patients should be treated in dedicated stroke units; each time 24 patients are treated in a stroke unit, instead of a conventional ward, one death and one dependence are prevented. This effect does not depend on age, severity, and the stroke subtype. For this reason, stroke unit care is the cornerstone of the treatment of stroke, aiming at the detection and management of life-threatening emergencies, stabilization of most physiological parameters, and prevention of early complications. In ischaemic strokes, besides this general management, specific therapies include intravenous recombinant tissue plasminogen activator, given as soon as possible and before 4.5 hours, otherwise aspirin 300 mg, immediately or after 24 hours in case of thrombolysis, and, in a few patients, decompressive surgery. In intracerebral haemorrhages, blood pressure lowering and haemostatic therapy, when needed, are the two targets, but surgery does not seem effective to reduce death and disability.
Conference papers on the topic "Spontaneous intracranial bleeding"
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JakloyazAy, A. M., and Oa H. dnagy. "CONGENITAL AFIBRINOGENAEMIA: DIAGNOSIS, CLINICAL FEATURES, FOLLOW-UP STUDY." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644856.
Full textAbstract:
Authors followed 6 cases of congenital afibrinogenae- mia (CA) by offsprings of two apparently unrelated families from the same village. The sex ratio was4.m/3.f. CA is a rare autosomal recessive disease. Controlling 76 family members authors detected 11 cases of moderate and 2 cases of severe hypofibrinogeneemia.Among them-without any bleeding tendency-the mother of one case and both parents of two siblings with CA*The lack of fibrinogen was confirmed biochemically and immunologically too. The only symptom ofthe Illness are the severe posttraumatic bleeding. They appear as epistax- is, bleeding of the gums, or anyother bleeding aiter minor or severe injuries*Intraarticular bleeding, as in haemophilia rarely occurs inCA. One of our patients had profuse haematurias, causedby renal calculi. The only therapy is the substitution with transfusions of fresh blood, plasma, or fibrinogen concentrates*The rise of posttransfusional lllnisses grows with the number of transfusions*Stomatological or surgical interventions could be performed only after correction of the dotting abnormalitySo, one of our patients was submitted to splenectomyfor spontaneous rupture at 12 years and to nephrectomy for severe pyelo-caliceal cal- culosis with 19.He recovered fully after both interventions but died at 21 years after a bicycle accidenti The five other patients deceased at the age of 5«resp. 10 months and at 6-lo-resp 12 years. In 3 cases there was a subdural hammorrhage, once an intracranial blee- dingCnon autopsiated)and once a severe intraabdoml- nal haemorrhage after an accidental traumatism of the abdominal wall. The care of the CA cases is mostly a pediatric proble. The frequency of the pottraumatic bleeding decrease with the growth*The schoolchildren are paying more attention to avoid injuries