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Journal articles on the topic 'Spontaneous rupture of membranes'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

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1

Yusuf, Abisowo Oshodi, Oyedeko MuyideenOladipo, TawaqualitAbimbolaOttun, Motunrayo Akinlusi Fatimat, and OnyinyechiChionuma Joy. "Maternal Demography and Neonatal Outcomes in Term Pre Labour Rupture of Membranes Versus Spontaneous Labour Preceding Ruptured Membranes in Lagos, Nigeria: A Comparative Study." International Journal of Innovative Science and Research Technology 8, no. 3 (2023): 1186–91. https://doi.org/10.5281/zenodo.7783889.

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Term prelabour rupture of membranescomplicates about 5% to 10% of term pregnancies and imposes therapeutic challenges upon the managing obstetrician. While spontaneous labour followed by ruptured membranes is the accepted default pathway towards delivery at term, comparative studies on term PROM and spontaneous onset of labour preceding ruptured membranes are scarce globally. Objective: To compare maternal socio-demography and neonatal outcomes of term PROM versus spontaneous onset of labour before membrane rupturein our tertiary facility. Methods: A prospective comparative study of 300 subjec

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Malak, TM, and SC Bell. "Fetal membranes structure and prelabour rupture." Fetal and Maternal Medicine Review 8, no. 3 (1996): 143–64. http://dx.doi.org/10.1017/s0965539500001583.

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In most pregnancies labour begins at term in the presence of intact fetal membranes. Without intervention the membranes usually spontaneously rupture near the end of the first stage of labour. In 10% of pregnancies that deliver at term the fetal membranes fail to maintain their structural integrity and this results in their “prelabour rupture”, defined as spontaneous rupture of membranes at least one hour before the onset of labour. In 95–98% of these cases at term, labour is precipitated within 48 hours. Although preterm birth, defined as birth prior to 37 completed weeks of pregnancy, occurs

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Sharma, Sanjay Kumar, and Madhusudan Dey. "Maternal and neonatal outcome in cases of premature rupture of membranes beyond 34 weeks of gestation." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 6, no. 4 (2017): 1302. http://dx.doi.org/10.18203/2320-1770.ijrcog20171382.

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Background: Preterm premature rupture of membrane (PPROM) and premature rupture of membrane (PROM) are associated with various maternal and neonatal complications. Management guidelines regarding rupture of membrane before labour is still controversial. The study was carried out to determine the various maternal and neonatal outcomes associated with rupture of membranes beyond 34 weeks of gestation.Methods: It was a prospective observational study carried out in a tertiary care teaching hospital for a period of one year. All the pregnant women with rupture of membrane beyond 34 weeks are inclu

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Atis Aydin, Alev, Kamuran Sanli, Zuhat Acar, Sema Suzen Caypınar, Deniz Acar, and Orhan Şahin. "Amniopatch Treatment in Spontaneous Previable Preterm Rupture of Membranes with Neonatal Outcomes." Women Health Care and Issues 5, no. 2 (2022): 01–06. http://dx.doi.org/10.31579/2642-9756/108.

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Objective: To evaluate the efficiency of amniopatch application in previable preterm rupture of membranes (pPPROM) between 17-23 gestational weeks of pregnancy. Methods: 30 pregnants with previable preterm rupture of membranes were given amniopatch as therapy option instead of termination.After one week of antibiotics and bed rest the volunteers were applied amniopatch under sonographic guidance by infusion of 100 mL of 0.9% Isotonic solution alternate infusions of platelets, normal saline and FFP with a total of 100cc of each maximally were given into amniotic cavity. During infusion, in the

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Adhikary, Sanchita, Shaorin Tanira, Arifa Sultana, Feroza Wazed, and Saleha Begum Chowdhury. "Maternal outcome in premature rupture of membrane - a study done in the tertiary Level specialized hospital in Bangladesh." Journal of Dhaka Medical College 22, no. 1 (2013): 26–29. http://dx.doi.org/10.3329/jdmc.v22i1.15600.

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Context: Premature rupture of membrane is defined as spontaneous rupture of membrane before the initiation of labour, which is one of the most common complications of pregnancy having a major impact on maternal outcome. The aim of the present study is to find out the effect of premature rupture of membrane on maternal outcome. Methods: A cross-sectional study was done in the Department of Obstetrics and Gynaecology of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, from February to July of 2008, on 50 pregnant women with more than 28 weeks of pregnancy both primigravid and multigra

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Khan, Farah, Nighat Ali Shah, Shabana Kanwal, Nusrat Shah, Falak Naz, and Urooj Naz. "Comparison of Conventional Treatment of Prom (Pre Labor Rupture of Membranes) with Active Treatment in Term Patients." Pakistan Journal of Medical & Health Sciences 16, no. 10 (2022): 413–15. http://dx.doi.org/10.53350/pjmhs221610413.

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Objectives: To compare outcome of conventional treatment of Pre labor rupture of membranes (PROM) with active treatment in term patients. Place and Duration: This study was Conducted in Family Medics Infertility and Maternity Centre Karachi from March 2022 till June 2022. Materials & Methods: We conducted a randomized control trial on 74 registered patients who presented to the labor room with term pregnancy and with the ruptured membranes at thirty-seven weeks or more gestation verified from the last normal menstrual period or a dating scan. Two groups were randomized as either spontaneou

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7

Danciu, Bianca Mihaela, Marina Ruxandra Oţelea, Marian Augustin Marincaş, Maria Niţescu, and Anca Angela Simionescu. "Is Spontaneous Preterm Prelabor of Membrane Rupture Irreversible? A Review of Potentially Curative Approaches." Biomedicines 11, no. 7 (2023): 1900. http://dx.doi.org/10.3390/biomedicines11071900.

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There is still no curative treatment for the spontaneous preterm prelabor rupture of membranes (sPPROM), the main cause of premature birth. Here, we summarize the most recent methods and materials used for sealing membranes after sPPROM. A literature search was conducted between 2013 and 2023 on reported newborns after membranes were sealed or on animal or tissue culture models. Fourteen studies describing the outcomes after using an amniopatch, an immunologic sealant, or a mechanical cervical adapter were included. According to these studies, an increase in the volume of amniotic fluid and th

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8

Banotra, Palvi, Zahoor Ahmad, and Samaa Haneef. "Fetal-Maternal Complications due to Premature Rupture of Membranes: A Prospective Study at Valley’s Famous Maternity Hospital." International Journal of Research and Review 9, no. 1 (2022): 610–13. http://dx.doi.org/10.52403/ijrr.20220170.

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Background: The fetal membrane remains intact till the labor starts in order to maintain the protective intrauterine fluid environment. However, sometimes membranes ruptures prematurely (PROM), a condition in which the disruption of fetal membranes takes place before the beginning of labor that ultimately results in spontaneous leakage of amniotic fluid. The present study is aimed to evaluate the feto-maternal outcomes due to premature rupture of membranes at term. Methods: A total 70 pregnant women patients with premature rupture of membranes after 37 completed weeks were selected in the stud

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Govaerts, Jolien, Patricia Cryns, and Yves Jacquemyn. "Spontaneous chorioamniotic membrane separation discovered by preterm prelabor rupture of membranes." Clinical Case Reports 7, no. 4 (2019): 762–65. http://dx.doi.org/10.1002/ccr3.2083.

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10

Fonseca, Linda, and Manju Monga. "Spontaneous Version Following Preterm Premature Rupture of Membranes." American Journal of Perinatology 23, no. 4 (2006): 201–4. http://dx.doi.org/10.1055/s-2006-934090.

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11

Sciscione, Anthony C. "Treatment of early preterm spontaneous rupture of membranes." American Journal of Obstetrics and Gynecology 187, no. 3 (2002): 818–19. http://dx.doi.org/10.1067/mob.2002.126622.

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12

Fonseca, Linda, and Manju Monga. "Spontaneous version with preterm premature rupture of membranes." American Journal of Obstetrics and Gynecology 191, no. 6 (2004): S85. http://dx.doi.org/10.1016/j.ajog.2004.10.184.

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Masruroh, Nely, Yonas Hadisubroto, and Rena Normasari. "The Difference of Asphyxia Neonatorum Incident between Very Preterm Labor That Is Followed or Not by Premature Rupture of Membranes at RSD dr. Soebandi of Jember." Journal of Agromedicine and Medical Sciences 4, no. 3 (2018): 147. http://dx.doi.org/10.19184/ams.v4i3.6394.

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Asphyxia neonatorum is an infant's inability to breathe spontaneously and regularly soon after birth. Risk factors of neonatal asphyxia are preterm labor and premature rupture of membranes. In the poor and developing countries there are many occurrences of asphyxia at gestation less than 32 weeks (very preterm). The aim of this study is to describe the incidence of asphyxia neonatorum in very preterm labor followed by premature rupture of membranes, describes the incidence of asphyxia neonatorum in very preterm labor that is not followed by premature rupture of membranes, and the difference of

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MN., Amulya, and Ashwini MS. "Maternal outcome in term premature rupture of membranes." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 8, no. 2 (2019): 576. http://dx.doi.org/10.18203/2320-1770.ijrcog20190287.

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Background: Rupture of Fetal membranes before the onset of labour is called PROM. Premature rupture of membrane (PROM) is associated with various complications. The present study is undertaken to study the maternal morbidity in term PROM.Methods: A prospective cross-sectional study was conducted at Vijaynagar institute of medical science Ballari for a period of one year by Department of Obstetrics and Gynecology from November 2016 to October 2017. 120 cases of spontaneous rupture of membranes with term gestation with confirmed PROM were selected.Results: PROM was common in age group of 20-29 y

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Mikhaylin, Yevgeniy Sergeyevich, Lada Anatolyevna Ivanova, Aleksey Gennadyevich Savitskiy, Sergey Georgiyevich Kucheryavyy, Roman Anatolyevich Krasnolobov, and Polina Yuryevna Krasnolobova. "A case of spontaneous splenic rupture in pregnancy." Journal of obstetrics and women's diseases 63, no. 4 (2014): 69–73. http://dx.doi.org/10.17816/jowd63469-73.

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The article provides an observation case of spontaneous splenic rupture in 33/34 weeks of pregnancy. The patient was under active-expectant management, because of premature rupture of membranes at term of 33 weeks. Suddenly, against a background of well-being, emerged clinical signs of massive intra-abdominal bleeding. During the revision of the abdominal cavity the rupture of the capsule of the spleen was detect. Cesarean section and splenectomy were performed. The postoperative period was uncomplicated, the patient was discharged home with the baby.

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Chen, Xiuying, and Baihui Zhao. "Perinatal outcomes with a copper intrauterine device in situ after 28 gestational weeks: A retrospective study of sole center in southeast China." Medicine 103, no. 36 (2024): e39448. http://dx.doi.org/10.1097/md.0000000000039448.

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The purpose of this study was to investigate the pregnancy outcomes with a copper intrauterine device (IUD) in situ after 28 gestational weeks and the association between pregnancy with copper IUDs and neonatal congenital malformations. This retrospective study had compared the singleton pregnancies with the copper IUDs in situ and without after 28 gestational weeks in 1 delivery center of southeast China. The main exposure was a copper IUD in uterine cavity with pregnancy. The pregnant outcomes as preterm birth, premature rupture of membranes, infections were observed and compared. We had als

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Furqooniyah, Nurul, Yonas Hadisubroto, and Bagus Hermansyah. "Keberhasilan Terapi Konservatif pada Persalinan Preterm Disertai dan Tanpa Disertai Ketuban Pecah Dini di RSD dr. Soebandi, Jember." Pustaka Kesehatan 7, no. 1 (2020): 20. http://dx.doi.org/10.19184/pk.v7i1.17587.

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Preterm delivery is the greatest cause of neonatal morbidity and mortality. Preterm delivery can be accompanied by premature rupture of membranes. Preterm delivery with and without premature rupture of membranes are managed by conservative therapy to delay birth. Rupture of membranes causes inadequate protection of the fetus. This study aimed to determine the success of conservative therapy in preterm delivery with and without premature rupture of membranes at Regional Hospital (RSD) dr. Soebandi Jember. The study used secondary data from medical records of pregnant women with spontaneous sing

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Sihombing, Jumaini Andriana, Muhammad Miqbel, and Batara Imanuel Sirait. "Relationship between Premature Rupture of the Membrane and Cesarean Delivery: Case from Jakarta, Indonesia." Asian Journal of Research in Infectious Diseases 12, no. 4 (2023): 41–51. http://dx.doi.org/10.9734/ajrid/2023/v12i4253.

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Premature rupture of membranes (PROM) is the spontaneous rupture of the membranes before the onset of signs of labor. It can occur both before term (<37 weeks) and after term (> 37 weeks). Caesarean delivery is a surgical technique to deliver the fetus through an incision in the abdominal wall and uterine wall. This procedure is performed to minimize all complications from premature rupture of membranes. This study aims to determine the relationship between premature rupture of membranes and delivery of sectio caesarea at the UKI General Hospital in the 2019 period by using a descriptive

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Khanum, Tahamina, Sheuly Begum, Monowara Begum, Tania Akbar, and Mosammad Tanbir Nahar Shamima. "Association of Premature Rupture of Membrane and Urinary Tract Infection among Pregnant Women." Journal of National Institute of Neurosciences Bangladesh 10, no. 1 (2025): 32–37. https://doi.org/10.3329/jninb.v10i1.76284.

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Background: Prelabour rupture of membranes among pregnant women is a common obstetrics problem encountered by the obstetricians. Objective: This present study was aimed to see the association of premature rupture of membrane and urinary tract infection among pregnant women. Methodology: This cross-sectional study was conducted in the Department of Obstetrics and Gynaecology at Enam Medical College, Savar, Dhaka, Bangladesh from January 2022 to December 2022 for a period of one year. Pregnant women with preterm premature rupture of membrane who were admitted in the Department of Obstetrics &amp

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Egan, D., and C. O'herlihy. "Expectant management of spontaneous rupture of membranes at term." Journal of Obstetrics and Gynaecology 8, no. 3 (1988): 243–47. http://dx.doi.org/10.3109/01443618809012292.

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21

Waldenström, Ulla, and Carl-Axel Nilsson. "Warm Tub Bath After Spontaneous Rupture of the Membranes." Birth 19, no. 2 (1992): 57–63. http://dx.doi.org/10.1111/j.1523-536x.1992.tb00381.x.

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WALDENSTRÖM, ULLA, and CARL-AXEL NILSSON. "Warm Tub Bath After Spontaneous Rupture of the Membranes." Obstetrical & Gynecological Survey 48, no. 3 (1993): 168–69. http://dx.doi.org/10.1097/00006254-199303000-00008.

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Hart, Jessica M., Anna M. Modest, Michele R. Hacker, Sarah Lambeth, and Mary Vadnais. "785: Spontaneous version after preterm prelabor rupture of membranes." American Journal of Obstetrics and Gynecology 222, no. 1 (2020): S497—S498. http://dx.doi.org/10.1016/j.ajog.2019.11.801.

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Chai, Mahalia, Susan P. Walker, Clyde Riley, Gregory E. Rice, Michael Permezel, and Martha Lappas. "Effect of Supracervical Apposition and Spontaneous Labour on Apoptosis and Matrix Metalloproteinases in Human Fetal Membranes." BioMed Research International 2013 (2013): 1–10. http://dx.doi.org/10.1155/2013/316146.

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Background. Apoptosis and matrix metalloproteinase (MMP-9) are capable of hydrolysing components of the extracellular matrix and weakening the fetal membranes which leads to eventual rupture, a key process of human parturition. The aim of this study was to determine the effect of supracervical apposition and spontaneous labour on apoptosis and MMP-9 in human fetal membranes at term.Methods. Fetal membranes were obtained from term non-labouring supracervical site (SCS) and compared to (i) a paired distal site (DS) or (ii) site of rupture (SOR) after spontaneous labour onset.Results. The express

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Mohan, Surekha S., Chamaraja Thippeveeranna, Naorem N. Singh, and Laiphrakpam R. Singh. "Analysis of risk factors, maternal and fetal outcome of spontaneous preterm premature rupture of membranes: a cross sectional study." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 6, no. 9 (2017): 3781. http://dx.doi.org/10.18203/2320-1770.ijrcog20173623.

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Background: Preterm premature rupture of membranes (PPROM) is one of the most common complications of pregnancy. It is an important cause of perinatal morbidity and mortality. Objective of present study was to determine incidence, risk factors, maternal, fetal outcome of PPROM occurring in patients attending a tertiary hospital in North Eastern India.Methods: This descriptive cross- sectional study was carried out in the department of Obstetrics and Gynecology, Regional Institute of Medical Sciences, Imphal, India. Out of 15,969 deliveries between July 2010 to December 2011, 358 pregnant patie

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DIGHE, SHWETAL, A. ZAIDI, and SAMI FARHAT. "SPONTANEOUS RUPTURE OF AMYLOID SPLEEN." Professional Medical Journal 15, no. 04 (2008): 537–39. http://dx.doi.org/10.29309/tpmj/2008.15.04.2858.

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.Primary systemic amyloidosis (AL) is characterized by the overproduction of immunoglobulin light chain proteins by amonoclonal, terminally differentiated B-lymphocyte or plasma cell clone. The free immunoglobulin light chains are deposited in an abnormalconformation as amyloid in a variety of organs in the body (1). Splenic involvement is seen in 4 -13% of cases, however amyloidosis causingspontaneous rupture is very rare with only 31 cases reported so far. We report a case of 60-year old, suffering from Primary AL amyloidosisand multiple myeloma involving the liver, spleen and GI tract, who

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Sai Bhavana, D., G. Shyamala, and B. Sujatha. "Accounts of adverse neonatal effects in preterm prelabor rupture of membranes: anticipating maternal platelet indices and C-reactive protein as effective biomarkers." NAMJ 17 (2023), no. 1, 17 (2023) (2023): 84–93. http://dx.doi.org/10.56936/18290825-2023.17.84-93.

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Present study aimed at determining maternal platelet indices in preterm prelabor rupture of membranes with adverse neonatal consequences. Comparing maternal C-reactive protein efficacy and platelet indices in predicting outcomes. Herein, 82 women with preterm prelabor rupture of membranes and 78 women with spontaneous preterm labor were studied. All women undertook complete blood count tests. The group of preterm prelabor rupture of membranes undertook additional C-reactive protein tests. Neonatal outcome data were compiled post-delivery, and results were compared. C-reactive protein efficacy

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Sai Bhavana, D., G. Shyamala, and B. Sujatha. "Accounts of adverse neonatal effects in preterm prelabor rupture of membranes: anticipating maternal platelet indices and C-reactive protein as effective biomarkers." NAMJ 17 (2023), no. 1, 17 (2023) (2023): 84–93. http://dx.doi.org/10.56936/18290825-2023.17.1-84.

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Present study aimed at determining maternal platelet indices in preterm prelabor rupture of membranes with adverse neonatal consequences. Comparing maternal C-reactive protein efficacy and platelet indices in predicting outcomes. Herein, 82 women with preterm prelabor rupture of membranes and 78 women with spontaneous preterm labor were studied. All women undertook complete blood count tests. The group of preterm prelabor rupture of membranes undertook additional C-reactive protein tests. Neonatal outcome data were compiled post-delivery, and results were compared. C-reactive protein efficacy

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Chauhan, Anjali, Bani Sarkar, and Kritika Tanwar. "Comparative evaluation of artificial rupture of membranes and spontaneous rupture of membranes on course of labour and feto-maternal outcomes." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 9, no. 10 (2020): 4160. http://dx.doi.org/10.18203/2320-1770.ijrcog20204306.

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Background: Present study was undertaken to do a comparative evaluation of artificial rupture of membrane (ARM) and spontaneous rupture of membrane (SRM) on the course of labour and feto-maternal outcome.Methods: It was prospective interventional randomized comparative study including 120 primigravidae (60 in ARM and SRM group each) with cervical dilatation ≥3 cm and intact membranes. Amniotomy was performed in ARM group after enrolment while no intervention in SRM group. Outcomes noted were duration of labor, mode of delivery, APGAR score, NICU stay.Results: Significant reduction seen in dura

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Kerslake, Siân, and Eboo Versi. "Perspectives in prelabour rupture of the membranes." Fetal and Maternal Medicine Review 4, no. 2 (1992): 79–86. http://dx.doi.org/10.1017/s0965539500000644.

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Spontaneous rupture of the membranes usually accompanies the onset of labour, but precedes it in 10% of cases. Management, however, is not clear-cut and various treatments offer both risks and benefits to mother and infant in terms of intervention and nonintervention. Policies have changed over the last decade, moving towards a more conservative approach against a background of improved social conditions and antenatal care. Despite a wealth of literature documenting these changes, randomized controlled trials and unbiased reviews make up only a small proportion of the total number of papers su

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Jiao, Anqi, Alexa N. Reilly, Tarik Benmarhnia, et al. "Fine Particulate Matter, Its Constituents, and Spontaneous Preterm Birth." Obstetrical & Gynecological Survey 80, no. 5 (2025): 278–80. https://doi.org/10.1097/01.ogx.0001113768.55844.6c.

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(Abstracted from JAMA Network Open 2024;7(11):e2444593) Spontaneous preterm birth (sPTB) occurs following spontaneous labor or preterm premature rupture of membranes. It accounts for up to 70% of all preterm births (PTBs) and can result from infection or inflammation, decidual hemorrhage, uterine over distention, and chronic or acute stress.

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Cloet, Leonore, Bart Lutin, and Bart De Keersmaecker. "Spontaneous Uterine Vessel Rupture in the Peripartum Period: A Case Report." Obstetrics and Gynaecology Cases - Reviews 10, no. 3 (2023): 1–4. https://doi.org/10.23937/2377-9004/1410246.

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Spontaneous uterine vessel rupture in the peripartum period is a rare but life-threatening condition. We report an unusual case of a spontaneous rupture of uterine vessels leading to hypovolemic shock, two hours postpartum. A 32-year-old patient, gravida 2 para 1, had a first uneventful pregnancy. She now had an induction of labor at a gestational age of 40 weeks 3 days, using prostaglandins, artificial rupture of membranes and oxytocin. Epidural analgesia was used for pain relief. After a short second stage of labor followed by a normal vaginal delivery, a girl with a birth weight of 4060g wa

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Mariko, Seydou, Nanko S. Bagayogo, Pierre Coulibaly, et al. "Premature Rupture of Membranes: Interventionist or Expectant Attitude? At the Maternity Ward of Sominé Dolo Hospital in Mopti Mali." SAS Journal of Medicine 7, no. 10 (2021): 571–75. http://dx.doi.org/10.36347/sasjm.2021.v07i10.013.

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Context: The premature rupture of membranes regardless of the term of pregnancy can compromise the outcome. The objective was to describe the management of premature rupture of membranes in the maternity unit of Sominé Dolo Hospital in Mopti. Methods and Results: The 12-month study from January to December 31, 2018 was conducted in the maternity ward of Sominé Dolo Hospital in Mopti. This was a prospective analytical study of the case / control survey type including 63 cases (sick) of women who had presented a premature rupture of the membranes matched to 63 controls (not sick) of pregnant wom

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Mourad, W. S., D. J. Bersano, P. B. Greenspan, and D. M. Harper. "Spontaneous rupture of unscarred uterus in a primigravida with preterm prelabour rupture of membranes." Case Reports 2015, jun08 1 (2015): bcr2014207321. http://dx.doi.org/10.1136/bcr-2014-207321.

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Aghajanian, Paola, Quy T. Nguyen, Naomi H. Greene, and Kimberly D. Gregory. "Can We Accurately Time the Administration of Antenatal Corticosteroids for Preterm Labor?" Obstetrics and Gynecology International 2016 (2016): 1–5. http://dx.doi.org/10.1155/2016/5054037.

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Background. Accurate timing of antenatal corticosteroids (ACS) has resulted in improved neonatal outcomes. Objectives. Our primary objective was to determine predictors for optimal timing of ACS in women presenting with spontaneous preterm labor. Study Design. A retrospective cohort study of women receiving ACS for spontaneous preterm birth was conducted. Women were included if they presented with preterm labor or preterm premature rupture of membranes. Accurate timing of ACS was defined as administration within 7 days of delivery. Maternal demographic and obstetrics characteristics were compa

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Hoskins, Nathanael N., Kathryn Brandt, and Tory Peterson. "Catastrophic Spontaneous Uterine and Bladder Rupture in an Unscarred Uterus." Transformative Medicine 3, no. 3 (2024): 95–97. http://dx.doi.org/10.54299/tmed/luyd5797.

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Introduction: Uterine rupture during pregnancy is a rare event which can be life-threatening for both the patient and the fetus. This case report describes a rare complication of uterine rupture which ultimately required a hysterectomy and extensive urologic reconstruction. Case Description: A 36-year-old patient presented to the hospital after term pre-labor rupture of membranes. The patient underwent induction of labor which ultimately resulted in a uterine rupture in an unscarred uterus. The rupture extended into the posterior bladder wall, right ureter, urethra, and anterior vaginal wall,

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Moon, Suji, Tun Naw Sut, Bo Kyeong Yoon, and Joshua A. Jackman. "Unraveling How Antimicrobial Lipid Mixtures Disrupt Virus-Mimicking Lipid Vesicles: A QCM-D Study." Biomimetics 9, no. 2 (2024): 67. http://dx.doi.org/10.3390/biomimetics9020067.

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Single-chain lipid amphiphiles such as fatty acids and monoglycerides are promising antimicrobial alternatives to replace industrial surfactants for membrane-enveloped pathogen inhibition. Biomimetic lipid membrane platforms in combination with label-free biosensing techniques offer a promising route to compare the membrane-disruptive properties of different fatty acids and monoglycerides individually and within mixtures. Until recently, most related studies have utilized planar model membrane platforms, and there is an outstanding need to investigate how antimicrobial lipid mixtures disrupt c

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Restucci, Brunella, Mariafrancesca Sgadari, Gerardo Fatone, et al. "Immunoexpression of Relaxin and Its Receptors in Stifle Joints of Dogs with Cranial Cruciate Ligament Disease." Animals 12, no. 7 (2022): 819. http://dx.doi.org/10.3390/ani12070819.

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The etiology of spontaneous cranial cruciate ligament rupture in dogs is unknown despite being one of the most impacting orthopedic diseases in dogs. Numerous studies have contributed to the understanding of a multifactorial pathogenesis, this, however, without identifying a pivotal link to explain progressive collagen degeneration and osteoarthritic changes. In human medicine, recent reports have identified relaxin as a triggering factor in ligament ruptures in knee and metacarpal joints. We thus hypothesized that relaxin might also play a role in canine cruciate ligament rupture. Relaxin’s p

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Magsi, Shahida, Sonia Gul Qureshi, Fatima Rajput, Basma Zia, and Inayatullah Magsi. "Frequency of Cesarean Section in Premature Rupture of Membranes." Pakistan Journal of Medical and Health Sciences 16, no. 8 (2022): 74–76. http://dx.doi.org/10.53350/pjmhs2216874.

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Background: Premature rupture of membranes (PROM) is always of clinical significance either it occurs before onset of labour at term or preterm. It is defined as spontaneous rupture of fetal membranes which results in leakage of amniotic fluid. PROM is related with maternal and perinatal morbidity and mortality if not treated sensibly on time, due not only to conditions causing it but also likelihood of emergency cesarean delivery. Aim: To ascertain frequency of C- section in women presented with premature rupture of membranes at tertiary care hospital. Study Design: Cross-sectional descriptiv

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Gopinath, Sowmya, Nuzrin Nazar N, Bhavani M H, and Rekha Gurumurthy. "A prospective study of clinical profile of premature rupture of membranes and its effect on maternal and perinatal outcome at term gestation in primigravida." Panacea Journal of Medical Sciences 14, no. 2 (2024): 366–70. http://dx.doi.org/10.18231/j.pjms.2024.065.

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Premature rupture of membranes (PROM) is defined as the spontaneous rupture of amniotic membranes with a release of amniotic fluid, before the onset of labor. If it occurs after 37 weeks of gestation, it is called as term PROM. The incidence of PROM worldwide varies between 5-10%.Out of which 80% occurs at term. In India, the incidence of PROM was reported as 7-12% in all labours.This study was a prospective, observational hospital based study which include the cases admitted to labour ward, Department of Obstetrics, District hospital, Tumakuru, Karnataka with Premature rupture of membranes or

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Gupta, Anjali, Sarika Gautam, Om Prakash, and Meenakshi Chauhan. "Early induction versus expectant management in prelabour rupture of membranes." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 7, no. 11 (2018): 4634. http://dx.doi.org/10.18203/2320-1770.ijrcog20184521.

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Background: Prelabour rupture of membrane defined as spontaneous rupture of membrane prior to the onset of regular uterine contractions. The incidence of PROM varies from 6-18%. Management of term PROM is not having specific guidelines leading to management dilemma.Methods: This prospective study was conducted on 100 women with singleton pregnancy, cephalic presentation with spontaneous PROM at term. The aim to compare maternal and perinatal outcome of early induction with expectant management in women with PROM. The patients were divided into two group expectant group and early induction grou

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Singh, Jigyasa, Vaibhav Kanti, and Vandana Verma. "Study of fetomaternal outcome in cases of premature rupture of membrane at tertiary care rural institute of Western Uttar Pradesh." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 9, no. 1 (2019): 77. http://dx.doi.org/10.18203/2320-1770.ijrcog20196000.

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Background: Premature rupture of membranes (PROM) is the rupture of the fetal membranes before the onset of labor. Preterm PROM complicates approximately 3 percent of pregnancies and leads to one third of preterm births. It increases the risk of prematurity and leads to a number of other perinatal and neonatal complications.Methods: This was a prospective study carried out at the department of obstetrics and gynaecology, UPUMS, Saifai from April 2018 to September 2018 (6 months study). Patients with Spontaneous rupture of membranes any time beyond 28th week of pregnancy, but before the onset o

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Theiler, Regan N., Russell R. Snyder, and Shaleen K. Theiler. "Dystroglycan in Human Fetal Membranes Decreases in Later Gestation and with Spontaneous Membrane Rupture." Gynecologic and Obstetric Investigation 79, no. 4 (2014): 244–49. http://dx.doi.org/10.1159/000367894.

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Erşahin, Suat Süphan. "The comparison of amniotic fluid nuclearfactor-kappa B levels in pregnant women who underwent cesarean section or normal vaginal labor." Perinatal Journal 29, no. 1 (2021): 8–12. http://dx.doi.org/10.2399/prn.21.0291002.

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Objective Inflammatory changes in the amniotic membranes during prenatal period have a critical important in the rupture of membranes and the onset of labor. The inflammatory changes in the membranes caused by normal vaginal labors and cesarean sections (C/S) are different than each other. Nuclear factor-kappa B (Nf- kB) is the basic cellular marker of the inflammation change in biological fluids and tissues. We planned this study to compare amniotic fluid NF-kB (AF-NF-kB) concentrations in normal vaginal labor cases and those who underwent non-emergency C/S. Methods One-hundred singleton term

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Chmait, R., D. Miller, A. Ghazaryan, L. Yedigarova, I. Seri, and T. M. Goodwin. "OP15.05: Spontaneous intertwin dividing membranes rupture and membranes detachment in twin-twin transfusion syndrome." Ultrasound in Obstetrics and Gynecology 30, no. 4 (2007): 507. http://dx.doi.org/10.1002/uog.4562.

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Ayad, I. A. A. "Vaginal misoprostol in managing premature rupture of membranes." Eastern Mediterranean Health Journal 8, no. 4-5 (2002): 515–20. http://dx.doi.org/10.26719/2002.8.4-5.515.

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We compared the efficacy of misoprostol with that of prostaglandin E2 in cervical ripening and labour induction. Thus 238 women with rupture of membranes beyond 36 weeks gestation without labour were randomized to receive 50 microg misoprostol vaginal gel or 5 mg of prostaglandin E2 gel. Bishop score was evaluated before drug application and 6 hours later. Clinical data and perinatal outcome were recorded. Mean time from induction to delivery and the need for oxytocin were significantly less in the misoprostol group. There were no significant differences in spontaneous labour rate, type of del

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Nahar, Nurun, Nadira Haque, nahreen Akhtar, et al. "Maternal and Fetal Outcome in Term Premature Rupture of Membrane." Dinajpur Medical College Journal 18, no. 01 (2025): 25–30. https://doi.org/10.69861/djmcj2025v18i1s5.

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Abstract Background: Premature rupture of membranes (PROM) is a significant obstetric desperation.PROMrefers to the breakingof fetal membranes before the onset of labor, resulting in spontaneous leakage of amniotic fluid. PROM, which occurs before 37 weeks of gestation is defined as preterm PROM and PROM that occurs after 37 weeks of gestation is defined as term PROM. It is associated with detrimental maternal and perinatal consequence. Method: This cross-sectional observational study was carried out in the Department of Obstetrics & Gynecology, Bangabandhu Sheikh Mujib Medical University

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Nguyen-Ngo, Caitlyn, Carlos Salomon, Andrew Lai, Jane C. Willcox, and Martha Lappas. "Anti-inflammatory effects of gallic acid in human gestational tissues in vitro." Reproduction 160, no. 4 (2020): 561–78. http://dx.doi.org/10.1530/rep-20-0249.

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Spontaneous preterm birth is the leading cause of neonatal mortality and morbidity globally. Activation of the maternal immune system leads to a downstream cascade of proinflammatory events that culminate in the activation of spontaneous uterine contractions and the rupture of the foetal membranes. Anti-inflammatory agents may be a novel therapeutic approach to prevent inflammation-induced myometrial contractions and premature rupture of foetal membranes. The polyphenol gallic acid has been previously shown to exert potent anti-inflammatory effects. Thus, this study aimed to determine the effe

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Watson, P., and D. M. Campbell. "Preterm Deliveries in Twin Pregnancies in Oxford." Acta geneticae medicae et gemellologiae: twin research 35, no. 3-4 (1986): 193–99. http://dx.doi.org/10.1017/s0001566000005705.

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AbstractThe incidence of preterm delivery among twin maternities in Oxford between 1973 and 1983, was 39.4%. Preterm delivery was more common in MZ than DZ twins, and this was associated with higher incidence of spontaneous rupture of the membranes associated with monozygosity.

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Quintero, Rubén A., Walter J. Morales, Patricia W. Bornick, Mary Allen, and Nenita Garabelis. "Surgical treatment of spontaneous rupture of membranes: The amniograft—First experience." American Journal of Obstetrics and Gynecology 186, no. 1 (2002): 155–57. http://dx.doi.org/10.1067/mob.2002.119185.

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