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Books on the topic 'Sporadic amyotrophic lateral sclerosis'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Brown, Robert H., Michael Swash, and Piera Pasinelli. Amyotrophic Lateral Sclerosis. 2nd ed. CRC Press, 2021. http://dx.doi.org/10.1201/9781003076445.

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2

Cosi, V., Ann C. Kato, W. Parlette, P. Pinelli, and M. Poloni, eds. Amyotrophic Lateral Sclerosis. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-5302-7.

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3

MD, Brown Robert H., Swash Michael, and Pasinelli Piera, eds. Amyotrophic lateral sclerosis. 2nd ed. Informa Healthcare, 2006.

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4

1947-, Brown Robert H., Meininger Vincent, and Swash Michael, eds. Amyotrophic lateral sclerosis. Martin Dunitz, 2000.

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5

National Institute of Neurological Disorders and Stroke (U.S.). Office of Communications and Public Liaison, ed. Amyotrophic lateral sclerosis. U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, 2000.

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6

1949-, Chad David A., and Pioro Erik P. 1955-, eds. Amyotrophic lateral sclerosis. F.A. Davis, 1998.

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7

Clifford, Rose F., ed. Amyotrophic lateral sclerosis. Demos, 1990.

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8

1952-, Brown Robert H., Meininger Vincent, and Swash Michael, eds. Amyotrophic lateral sclerosis. Martin Dunitz, 2000.

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9

Hiroshi, Mitsumoto, Przedborski Serge, and Gordon Paul H, eds. Amyotrophic lateral sclerosis. Taylor & Francis, 2006.

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10

Ludwig, Gutmann, and Mitsumoto Hiroshi, eds. Advances in amyotrophic lateral sclerosis. Little, Brown, 1996.

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11

G, Farrell Jason, ed. New amyotrophic lateral sclerosis research. Nova Biomedical Books, 2008.

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12

A, Murray Christine, ed. Amyotrophic lateral sclerosis: New research. Nova Biomedical Books, 2006.

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13

1941-, Smith Richard Alan, ed. Handbook of amyotrophic lateral sclerosis. Dekker, 1992.

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14

Hiroshi, Mitsumoto, ed. Amyotrophic lateral sclerosis: A guide for patients and families. 3rd ed. Demos Health, 2009.

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15

National Institute of Neurological Disorders and Stroke (U.S.). Office of Communications and Public Liaison. ALS (Amyotrophic lateral sclerosis) fact sheet. National Institutes of Health, 2010.

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16

Perez-Torres, Eduardo J. Retromer deficiency in amyotrophic lateral sclerosis. [publisher not identified], 2020.

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17

1921-, Tsubaki Tadao, and Yase Yoshirō, eds. Amyotrophic lateral sclerosis: Recent advances in research and treatment : proceedings of the International Conference on Amyotrophic Lateral Sclerosis, Kyoto, Japan, 29-31, October 1987. Excerpta Medica, 1988.

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18

Serratrice, Georges. Pathogenesis and therapy of amyotrophic lateral sclerosis. Lippincott-Raven, 1995.

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19

Guion, Lee. Respiratory management of ALS: Amyotrophic lateral sclerosis. Jones and Bartlett, 2010.

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20

T, Serratrice Georges, and Munsat Theodore L, eds. Pathogenesis and therapy of amyotrophic lateral sclerosis. Lippincott-Raven, 1995.

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21

M, Belsh Jerry, and Schiffman Philip L, eds. Amyotrophic lateral sclerosis: Diagnosis and management for the clinician. Futura, 1996.

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22

1948-, Hunter Maggie, ed. Motor neurone disease. Routledge, 1998.

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23

1924-, Hudson Arthur J., and Canadian Congress of Neurological Sciences (22nd : 1987 : Vancouver, B.C.), eds. Amyotrophic lateral sclerosis: Concepts in pathogenesis and etiology. University of Toronto Press, 1990.

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24

Scott, Donald W. (Donald William) 1924. Amyotrophic lateral sclerosis: The probable cause, a possible cure. Trafford, 2002.

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25

Amyotrophic Lateral Sclerosis Society of Canada., ed. Resources for ALS healthcare providers. The Society, 1994.

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26

Wainger, Brian J. Amyotrophic Lateral Sclerosis. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0028.

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Mouse and cellular models of ALS including stem cells have revealed tremendous insight into the molecular processes that lead to ALS. Models of ALS and other neurodegenerative diseases have led to emergent molecular themes that span several diseases. Future models must account for neuronal subtype specificity of different neurodegenerative diseases, particularly between tightly related diseases such as FTD and ALS. Human iPSC-derived motor neurons offer promise both with regard to the use of human cells and in particular the ability to model sporadic disease, which is critically important give

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27

O’Reilly, Éilis J. Epidemiology of Amyotrophic Lateral Sclerosis. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0025.

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The epidemiology of ALS is an emerging field and, like the epidemiology of cardiovascular disease and cancer in the mid last century, requires time for convergence of findings. There appears to be a genetic influence, and one study of twins found that heritability of sporadic ALS is 60%. At present it is thought that 60$ to 70% of genetic mutations responsible for fALS in populations of European ancestry are known. SOD1 mutations were the earliest discoveries in fALS. Subsequently, mutations were identified in TARDBP, which encodes TDP-43 protein found in neuronal inclusions in fALS and fronto

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28

Aguirre, T. Genetic and Functional Studies of the Cu/Zn Superoxide Dismutase Gene in Belgian Patients with Familial or Sporadic Amyotrophic Lateral Sclerosis. Leuven University Press, 1998.

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29

Hayertz, Marchelle. Amyotrophic Lateral Sclerosis Treatment : Amyotrophic Lateral Sclerosis Treatment and Management: Amyotrophic Lateral Sclerosis Pronunciation. Independently Published, 2021.

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30

Mitsumoto, Hiroshi, Serge Przedborski, and Paul H. Gordon. Amyotrophic Lateral Sclerosis. Taylor & Francis Group, 2005.

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31

Pagnini, Francesco, and Zachary Simmons, eds. Amyotrophic Lateral Sclerosis. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198757726.001.0001.

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Amyotrophic lateral sclerosis: Understanding and optimizing quality of life and psychological well-being presents a comprehensive and up-to-date review of the enhancement of the lives of people with amyotrophic lateral sclerosis (ALS) and their caregivers. ALS is a progressive, fatal neurodegenerative disorder. No current medical therapy can reverse or stop its progression, and the promotion of quality of life and psychological well-being is a central component of ALS care. Health care professionals who work in this field should incorporate attention to psychological, emotional, and relational

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32

Ferraiuolo, Laura, and Stephen J. Kolb. Amyotrophic Lateral Sclerosis. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0026.

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An overriding mystery of ALS pathogenesis orbits around the molecular basis of selective motor neuron vulnerability and clouds our view. There are likely mechanisms involved in the initiation of motor neuron loss and mechanisms involved in the progression of motor neuron loss once initiated. Motor neuron vulnerability is likely related to the unique biological characteristics of these cells. This chapter introduces central molecular pathways that appear to be involved in the pathogenesis of ALS, and highlights why dysregulation of these mechanisms could lead to motor neuron death. Indeed, ther

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33

Harms, Matthew B., and Timothy M. Miller. Amyotrophic Lateral Sclerosis. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0027.

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Recent advances in sequencing technologies have dramatically expanded the number of genes associated with amyotrophic lateral sclerosis, including rare but highly penetrant causative mutations as well as common risk alleles. This chapter discusses these gene discoveries and how they have implicated a diverse array of biological pathways essential for motor neuron health and have begun to inform our understanding of ALS pathogenesis as a heterogeneous and multistep process. Insights from these discoveries are leading to a new generation of targeted therapies directed at specific genes and are p

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34

Harris, Brent T., Galam A. Khan, and Saed Sadeghi. Amyotrophic Lateral Sclerosis. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0029.

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Although the basic gross and microscopic pathological changes in amyotrophic lateral sclerosis (ALS) have been known for more than 100 years, emerging technology and research into the cellular and molecular changes found in this disease are challenging our understanding about the pathogenesis and pathophysiology. All cell types of the CNS/PNS as well as circulating immune cells have been implicated in the pathology of ALS. Numerous genes, their proteins, and environmental factors have also been associated. However, we still do not understand the specific gene-environmental interactions that br

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35

Mitsumoto, Hiroshi, Serge Przedborski, and Paul H. Gordon, eds. Amyotrophic Lateral Sclerosis. CRC Press, 2005. http://dx.doi.org/10.1201/b14133.

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36

Sattler, Rita, and Jeffrey Rothstein. Amyotrophic Lateral Sclerosis. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199794591.003.0063.

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This is a digitally enhanced text. Readers can also see the coverage of this topic area in the second edition of Neuroglia. The second edition of Neuroglia was first published digitally in Oxford Scholarship Online and the bibliographic details provided, if cited, will direct people to that version of the text. Readers can also see the coverage of this topic area in the ...

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37

Araki, Toshiyuki, ed. Amyotrophic Lateral Sclerosis. Exon Publications, 2021. http://dx.doi.org/10.36255/exonpublications.amyotrophiclateralsclerosis.2021.

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38

Maurer, Martin, ed. Amyotrophic Lateral Sclerosis. InTech, 2012. http://dx.doi.org/10.5772/1054.

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39

Amyotrophic Lateral Sclerosis. ReadHowYouWant.com, Limited, 2010.

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40

Swash, Michael, Robert Brown, and Piera Pasinelli. Amyotrophic Lateral Sclerosis. Taylor & Francis Group, 2006.

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41

Swash, Michael, Robert Brown, and Piera Pasinelli. Amyotrophic Lateral Sclerosis. Taylor & Francis Group, 2005.

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42

Mitsumoto, Hiroshi, Serge Przedborski, and Paul H. Gordon. Amyotrophic Lateral Sclerosis. Taylor & Francis Group, 2019.

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43

Gelinas, Deborah, and Miller Robert. Amyotrophic Lateral Sclerosis. Springer Publishing Company, Incorporated, 2010.

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44

Estevez, Alvaro G., Jin Hee Shin, and Fabian H. Rossi. Amyotrophic Lateral Sclerosis. DI Press, 2022.

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45

Brown, Jr Robert H., Vincent Meininger, and Michael Swash. Amyotrophic Lateral Sclerosis. 2nd ed. Informa Healthcare, 2000.

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46

Gelinas, Deborah, Patricia O'Connor, and Robert G. Miller. Amyotrophic Lateral Sclerosis. Springer Publishing Company, Incorporated, 2005.

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47

Omlin, Ernest. Amyotrophic Lateral Sclerosis : Genetics Associated W/ ALS: Amyotrophic Lateral Sclerosis Prognosis. Independently Published, 2021.

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48

Nostro, Trista. Amyotrophic Lateral Sclerosis Radiology : History of ALS: Amyotrophic Lateral Sclerosis Symptoms. Independently Published, 2021.

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49

Murray, Christine A. Amyotrophic Lateral Sclerosis: New Research. Nova Biomedical Books, 2004.

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50

Brown, Robert H., Michael Swash, and Piera Pasinelli. Amyotrophic Lateral Sclerosis Second Edition. Taylor & Francis Group, 2019.

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