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Journal articles on the topic 'Spray-dried nanoemulsion'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

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1

Rahman, Mohammad Akhlaquer. "Spray-dried nanoemulsion for improved oral delivery of silymarin against hepatic cancer cells." Journal of Drug Delivery and Therapeutics 12, no. 3-S (2022): 7–14. http://dx.doi.org/10.22270/jddt.v12i3-s.5479.

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Silymarin recognized for numerous activities, but the use is limited due to poor aqueous solubility, inefficient intestinal permeability, and low-erratic bioavailability. The aim of the current research was formulation of spray-dried nanoemulsion to enhance the solubility of silymarin. The nanoemulsion was prepared by aqueous titration method, spray died and characterized for thermal analysis by diffraction scanning calorimetry, crystallography analysis by x-ray diffraction, surface morphology by scanning electron microscopy. The reconstitution properties were determining for droplet size, pol

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2

Pradana, Aditya Trias, Garnpimol C. Ritthidej, Vudhiporn Limprasutr, Ausana Wongtayan, Vimolmas Lipipun, and Iksen. "Antihypertensive activity of spray-dried nanoemulsion containing Asiatic acid-Palm oil in high salt diet-fed rats." Pharmacia 71 (March 5, 2024): 1–10. http://dx.doi.org/10.3897/pharmacia.71.e115091.

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Asiatic acid (AA) is a compound isolated from Centella asiatica, which possesses significant antihypertensive activity. Several studies have shown that its hypertensive activity can be attributed to various mechanisms, such as Angiotensin-Converting-Enzyme (ACE) inhibition in the renin-angiotensin-aldosterone system (RAAS) pathway. Meanwhile, palm oil (PO) is an antioxidant, which has proven to have synergistic effects with the compound by preventing arterial thrombosis and atherosclerosis. Despite these synergistic effects, AA dosage in antihypertensive therapy has been reported to be relativ

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Pradana, Aditya Trias, Garnpimol C. Ritthidej, Vudhiporn Limprasutr, Ausana Wongtayan, Vimolmas Lipipun, and Iksen. "Antihypertensive activity of spray-dried nanoemulsion containing Asiatic acid-Palm oil in high salt diet-fed rats." Pharmacia 71, no. () (2024): 1–10. https://doi.org/10.3897/pharmacia.71.e115091.

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Asiatic acid (AA) is a compound isolated from <i>Centella asiatica</i>, which possesses significant antihypertensive activity. Several studies have shown that its hypertensive activity can be attributed to various mechanisms, such as Angiotensin-Converting-Enzyme (ACE) inhibition in the renin-angiotensin-aldosterone system (RAAS) pathway. Meanwhile, palm oil (PO) is an antioxidant, which has proven to have synergistic effects with the compound by preventing arterial thrombosis and atherosclerosis. Despite these synergistic effects, AA dosage in antihypertensive therapy has been reported to be

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4

MIN, Ji-Young, Sung-Il AHN, Yun-Kyung LEE, Hae-Soo KWAK, and Yoon Hyuk CHANG. "Optimized conditions to produce water-in-oil-in-water nanoemulsion and spray-dried nanocapsule of red ginseng extract." Food Science and Technology 38, no. 3 (2018): 485–92. http://dx.doi.org/10.1590/fst.09517.

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5

Ogrodowska, Dorota, Iwona Zofia Konopka, Grzegorz Dąbrowski, et al. "Impact of Wall Material Composition (Maltodextrin vs. Inulin vs. Nutriose) and Emulsion Preparation System (Nano- vs. Microemulsion) on Properties of Spray-Dried Linseed Oil." Molecules 30, no. 1 (2025): 171. https://doi.org/10.3390/molecules30010171.

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The aim of this study was to compare the functional properties of linseed oil powders made of three types of wall material (OSA starch + maltodextrin, OSA starch + nutriose, and OSA starch + inulin) and two types of emulsion phases (micro- and nanoemulsion). For these independent variables, the properties of the prepared emulsions (flow curves and viscosity) and the resulting powders (encapsulation efficiency, particle size distribution, water activity, bulk and tapped density, Carr’s index, color parameters, and thermal stability) were determined. The results showed that emulsion viscosity an

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6

Jang, Hangeul, Nahyun Kim, and Sung Giu Jin. "Development of a Carvedilol-Loaded Solid Self-Nanoemulsifying System with Increased Solubility and Bioavailability Using Mesoporous Silica Nanoparticles." International Journal of Molecular Sciences 26, no. 4 (2025): 1592. https://doi.org/10.3390/ijms26041592.

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This study developed a solid self-nanoemulsifying drug delivery system (S-SNEDDS) to improve the oral bioavailability of poorly soluble carvedilol using mesoporous silica nanoparticles (MSNs). The liquid self-nanoemulsifying drug delivery system (L-SNEDDS) consisted of carvedilol, Peceol, Tween 80, and Labrasol in a weight ratio of 10:25:50:25. The liquid SNEDDS was suspended in MSN at various ratios and spray-dried to produce S-SNEDDS. The emulsion size, PDI, solubility, and dissolution of various ratios of MSN were evaluated to make the optimal S-SNEDDS. The optimal S-SNEDDS, manufactured us

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7

Teow, Shuh June, Hew Weng Choy, Yih Phing Khor, et al. "Storage stability and sensory evaluation of tocotrienol-rich-fraction-fortified mayonnaise." International Food Research Journal 32, no. 1 (2025): 41–52. https://doi.org/10.47836/ifrj.32.1.03.

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Tocotrienol, a well-known antioxidant, was encapsulated within microcapsule for application in mayonnaise to determine the storage stability and sensory evaluation. Tocotrienol-rich fraction (TRF) nanoemulsion was first prepared by treated pea protein isolate-flaxseed gum complex, which was then spray dried into microcapsule using maltodextrin-starch sodium octenyl succinate. The present work aimed to determine the physico-chemical, oxidative, and sensory properties of TRF-fortified mayonnaises. Firstly, the control (C-Mayo) and TRF-fortified mayonnaise produced from microcapsule (M-mayo) and

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8

Maher, P. G., Y. H. Roos, K. N. Kilcawley, M. A. E. Auty, and M. A. Fenelon. "Levels of pentanal and hexanal in spray dried nanoemulsions." LWT - Food Science and Technology 63, no. 2 (2015): 1069–75. http://dx.doi.org/10.1016/j.lwt.2015.04.044.

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9

Maher, P. G., M. A. E. Auty, Y. H. Roos, L. M. Zychowski, and M. A. Fenelon. "Microstructure and lactose crystallization properties in spray dried nanoemulsions." Food Structure 3 (January 2015): 1–11. http://dx.doi.org/10.1016/j.foostr.2014.10.001.

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10

Mujica-Álvarez, Javiera, O. Gil-Castell, Pabla A. Barra, et al. "Encapsulation of Vitamins A and E as Spray-Dried Additives for the Feed Industry." Molecules 25, no. 6 (2020): 1357. http://dx.doi.org/10.3390/molecules25061357.

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Encapsulated fat-soluble powders containing vitamin A (VA) and E (VE) were prepared as a feasible additive for extruded feed products. The effect of the encapsulating agents (Capsul-CAP®, sodium caseinate-SC) in combination with Tween 80 (TW) as an emulsifier and maltodextrin (MD) as a wall material on the physicochemical properties of emulsions and powders was evaluated. First, nanoemulsions containing MD:CAP:TW:VA/VE and MD:SC:TW:VA/VE were prepared and characterized. Then, powders were obtained by means of spray-drying and analyzed in terms of the product yield, encapsulation efficiency, mo

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11

Maher, Patrick G., Yrjö H. Roos, and Mark A. Fenelon. "Physicochemical properties of spray dried nanoemulsions with varying final water and sugar contents." Journal of Food Engineering 126 (April 2014): 113–19. http://dx.doi.org/10.1016/j.jfoodeng.2013.11.001.

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12

Baghi, Fatemeh, Sami Ghnimi, Emilie Dumas, and Adem Gharsallaoui. "Microencapsulation of Antimicrobial trans-Cinnamaldehyde: Effect of Emulsifier Type, pH, and Drying Technique." Applied Sciences 13, no. 10 (2023): 6184. http://dx.doi.org/10.3390/app13106184.

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Two plant-based emulsifiers, soybean lecithin and pea protein isolate, were studied for their emulsifying and encapsulating capacities of an antimicrobial molecule, trans-cinnamaldehyde (TC), at two different pH values, three and seven, and after drying with two different techniques, spray-drying and freeze-drying. To characterize the obtained capsules, various physicochemical tests were conducted to examine particle size, encapsulation efficiency, thermal and moisture stability, and powder morphology. The spray-dried (SD) and freeze-dried (FD) powders had an average particle size of 8.35 µm a

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13

Myat, Htoo Htet, and Garnpimol C. Ritthidej. "Impact of formulation parameters on physical characteristics of spray dried nanoemulsions and their reconstitutions." Asian Journal of Pharmaceutical Sciences 11, no. 1 (2016): 197–98. http://dx.doi.org/10.1016/j.ajps.2015.11.038.

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14

Liang, Rong, Qingrong Huang, Jianguo Ma, Charles F. Shoemaker, and Fang Zhong. "Effect of relative humidity on the store stability of spray-dried beta-carotene nanoemulsions." Food Hydrocolloids 33, no. 2 (2013): 225–33. http://dx.doi.org/10.1016/j.foodhyd.2013.03.015.

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15

Rehman, Abdur, Qunyi Tong, Seid Mahdi Jafari, et al. "Spray dried nanoemulsions loaded with curcumin, resveratrol, and borage seed oil: The role of two different modified starches as encapsulating materials." International Journal of Biological Macromolecules 186 (September 2021): 820–28. http://dx.doi.org/10.1016/j.ijbiomac.2021.07.076.

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16

Bonferoni, M. C., F. Riva, A. Invernizzi, et al. "Alpha tocopherol loaded chitosan oleate nanoemulsions for wound healing. Evaluation on cell lines and ex vivo human biopsies, and stabilization in spray dried Trojan microparticles." European Journal of Pharmaceutics and Biopharmaceutics 123 (February 2018): 31–41. http://dx.doi.org/10.1016/j.ejpb.2017.11.008.

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17

Sari, Rizki Tribuana, Ade Maria Ulfa, and Vida Elsyana. "Uji Stabilitas dan Antibakteri Spray Nanoemulsi Ekstrak Bunga Telang (Clitoria Ternatea L.) dengan Variasi Polietilen Glikol (Peg) 400." Journal of Islamic Medicine 8, no. 1 (2024). https://doi.org/10.18860/jim.v8i1.23292.

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Nanotechnology has been used in drug delivery systems because it can improve drug penetration and absorption. PEG 400 can reduce interfacial tension and create a stable nanoemulsion system that also increase the ability of the active substance to inhibit bacterial growth. The purpose of this study was to identify the stability of spray nanoemulsion preparations of (Clitoria ternatea L.) with variations of PEG 400 and test the antibacterial activity against Staphylococcus epiermidis. Extraction using maceration method then freeze dried the yield obtained was 29.33%. The preparation was carried

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18

Karami, Malihe, Ali Fazlara, Mehdi Zarei, Behzad Sharif Makhmal Zadeh, and Mehdi Safdarian. "Development of Sesame Oil Loaded to Maltodextrin/Acacia Gum-Coated Nanoemulsion and Investigation of its Physicochemical Properties." Jundishapur Journal of Natural Pharmaceutical Products 19, no. 4 (2024). http://dx.doi.org/10.5812/jjnpp-149354.

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Background: Sesame oil (SO) is one of the edible oils beneficial to health. The use of SO due to its high content of antioxidants and unsaturated fatty acids has many applications in the production of functional foods and pharmaceuticals. In recent years, many efforts have been made to use nanotechnology, including encapsulation technology, to protect functional foods from destructive environmental factors and thereby extend the shelf life of foods. Objectives: This study aimed to prepare and investigate the Physicochemical characteristics of SO-nanoemulsion coated with maltodextrin/acacia gum

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19

Gomez, Mellissa, Mushtaq Ahmed, Shibali Das, et al. "Development and Testing of a Spray-Dried Tuberculosis Vaccine Candidate in a Mouse Model." Frontiers in Pharmacology 12 (January 21, 2022). http://dx.doi.org/10.3389/fphar.2021.799034.

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Converting a vaccine into a thermostable dry powder is advantageous as it reduces the resource burden linked with the cold chain and provides flexibility in dosage and administration through different routes. Such a dry powder presentation may be especially useful in the development of a vaccine towards the respiratory infectious disease tuberculosis (TB). This study assesses the immunogenicity and protective efficacy of spray-dried ID93+GLA-SE, a promising TB vaccine candidate, against Mycobacterium tuberculosis (Mtb) in a murine model when administered via different routes. Four administrati

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20

Meghana, S. Kamble* Varsha G. Borwandkar Suraj S. Mane Omkar R. Mane Pravin P. Aute Dr. Pravin D. Chaudhari. "Formulation and Evaluation of Lipid Based Nanoemulsion of Glimepiride using self-emulsifying Technology." INDO AMERICAN JOURNAL OF PHARMACEUTICAL RESEARCH 02, no. 03 (2012). https://doi.org/10.5281/zenodo.2295720.

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The aim of the present study was to develop and optimize Self nanoemulsifying drug delivery system (SNEDDS) of glimepiride and convert to solid Self nanoemulsifying drug delivery system (S-SNEDDS). For screening purpose the solubility of glimepiride in various oils (Lipids), surfactants and co-surfactants was determined to select a suitable combination of these ingredients. Emulsification efficiency was determined and also pseudo-ternary phase diagrams were constructed. From the results of screening, four formulation variables were selected X1 Caproyl®90 (Lipid), X2 Cremophor®EL (Surfa

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21

Sassi, Ghada, Shiv Shankar, Lily Jaiswal, Stephane Salmieri, Salwa Karboune, and Monique Lacroix. "Nanoemulsion-based spray-dried formulation of essential oils, whey protein isolate, and maltodextrin: An approach for antifungal preservation of grated mozzarella cheese." International Dairy Journal, February 2024, 105919. http://dx.doi.org/10.1016/j.idairyj.2024.105919.

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22

Thi Hai Yen, Tran, Nguyen Thi Yen, Nguyen Canh Hung, et al. "Development of Solid Self – Nanoemulsified Drug Delivery System Containing Rosuvastatin." VNU Journal of Science: Medical and Pharmaceutical Sciences 36, no. 3 (2020). http://dx.doi.org/10.25073/2588-1132/vnumps.4253.

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This study aims to solidify the self-nanoemulsifying drug delivery system with rosuvastatin (SNEDDS Ros) for application in solid dosage forms. The liquid SNEDDS Ros system is solidified by granulation and spray drying methods. Solid SNEDDS Ros was evaluated on the drug content, the Carr index, nanoemulsification efficiency and several criteria of nanoemulsion, formed after emulsification of solid SNEDDS Ros, such as droplet size, polydispersion index (PDI), the drug proportion in the oil phase. The study results show that solid SNEDDS Ros, prepared by granulation method using Prosolv SMCC 90

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23

Anvar, Seyed Amirali, Dorsa Rahimyan, Leila Golestan, Asiyeh Shojaee, and Rezvan Pourahmad. "Butter fortified with spray‐dried encapsulated Ferulago angulata extract nanoemulsion and postbiotic metabolite of Lactiplantibacillus plantarum subsp. plantarum improves its physicochemical, microbiological and sensory properties." International Journal of Dairy Technology, January 30, 2023. http://dx.doi.org/10.1111/1471-0307.12939.

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24

Amante, Chiara, Valentina Andretto, Annalisa Rosso, et al. "Alginate-pectin microparticles loaded with nanoemulsions as nanocomposites for wound healing." Drug Delivery and Translational Research, December 13, 2022. http://dx.doi.org/10.1007/s13346-022-01257-9.

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AbstractThis work combines natural polymers with nanoemulsions (NEs) to formulate nanocomposites as an innovative wound dressing. Spray-drying has been used to produce alginate-pectin in situ gelling powders as carriers for NEs loaded with curcumin (CCM), a model antimicrobial drug. The influence of NEs encapsulation in polymer-based microparticles was studied in terms of particle size distribution, morphology, and stability after spray-drying. NEs loading did not affect the size of microparticles which was around 3.5 µm, while the shape and surface morphology analyzed using scanning electron

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25

López, María D., Manuel Cantó-Tejero, and María J. Pascual-Villalobos. "New Insights Into Biopesticides: Solid and Liquid Formulations of Essential Oils and Derivatives." Frontiers in Agronomy 3 (November 22, 2021). http://dx.doi.org/10.3389/fagro.2021.763530.

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Essential oils and derivatives have shown effective insecticidal activity against different agricultural pests. However, the use of these bioactive compounds can result in negative effects due to their high volatility and difficult handling. Both solid and liquid formulations of essential oils have been developed in recent years. Currently, there are some commercial products available in the market, but they are still scarce and mainly based on liquid formulations. Solid formulations developed through spray-drying, including complex or micro/nanospheres, present differences in encapsulation ef

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26

Rivera-Pérez, E., A. Escobar-Ortiz, Iza Fernanda Pérez-Ramírez, et al. "Encapsulation of spray-dried curcumin nanoemulsions to develop a supplement with ingredients for the control of osteoarthritis." Journal of Drug Delivery Science and Technology, February 2023, 104299. http://dx.doi.org/10.1016/j.jddst.2023.104299.

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