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Journal articles on the topic 'Spray drying and Fast dissolving tablet'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Aniket, G. Karodade, P. Wable Aniket, kharbal Gopal, S. Bhagat Sunil, and P. Deshmukh Swati. "Fast dissolving tablet." GSC Biological and Pharmaceutical Sciences 27, no. 1 (2024): 001–7. https://doi.org/10.5281/zenodo.11951879.

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Fast dissolving tablets have emerged as a popular dosage form, particularly beneficial for pediatric and geriatric patients facing challenges such as dysphagia or hand tremors. These tablets dissolve quickly in saliva without needing water, enhancing compliance and effectiveness of therapy. They offer advantages like easy portability, accurate dosing, and improved bioavailability. Various technologies, including spray drying and melt granulation, have been developed for their manufacturing. This review provides comprehensive information on fast dissolving tablets, covering their definition, ad

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2

Aniket G. Karodade, Aniket P. Wable, Gopal kharbal, Sunil S. Bhagat, and Swati P. Deshmukh. "Fast dissolving tablet." GSC Biological and Pharmaceutical Sciences 27, no. 1 (2024): 001–7. http://dx.doi.org/10.30574/gscbps.2024.27.1.0096.

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Fast dissolving tablets have emerged as a popular dosage form, particularly beneficial for pediatric and geriatric patients facing challenges such as dysphagia or hand tremors. These tablets dissolve quickly in saliva without needing water, enhancing compliance and effectiveness of therapy. They offer advantages like easy portability, accurate dosing, and improved bioavailability. Various technologies, including spray drying and melt granulation, have been developed for their manufacturing. This review provides comprehensive information on fast dissolving tablets, covering their definition, ad

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3

Rushikesh, Bhanage* Dhanashri Ghude Dr. Anil Pawar. "Fast Dissolving Tablet: An Overview." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 5190–97. https://doi.org/10.5281/zenodo.15563036.

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Oral delivery is the preferred route of drug delivery in the pharmaceutical industry because to its safety, convenience, and cost-effectiveness, with high patient compliance. Fast dissolving tablets have become a prevalent and widely recognized dose form, particularly for young patients due to the insufficient development of their muscular and neural systems, as well as for senior individuals experiencing Parkinson’s disease or hand tremors. Nowadays, a small number of solid dosage forms, such as tablets and capsules, have issues such dysphagia, which makes it difficult to swallow. This

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4

Abdul, Qadir, Singh Bhavana, Joshi Deepika, and Semwal Nidhi. "Fast dissolving tablet: An updated review." World Journal of Biology Pharmacy and Health Sciences 11, no. 3 (2022): 052–59. https://doi.org/10.5281/zenodo.7181372.

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Improved patient management and patient tracking are essential to the development of an oral drug delivery system that remains a popular drug delivery route despite various maladies. Fast-dispersing pills (FDTs) have found growing demand over the past decade, and the field has become a fast-growing area in the pharmaceutical industry. The popularity and usefulness of the construction has led to the development of many FDT technologies. These are ways to make the tablet dissolve faster and spill in the mouth for five seconds without chewing and the need for beneficial water especially for child

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Rahane, RD, and Punit R. Rachh. "A REVIEW ON FAST DISSOLVING TABLET." Journal of Drug Delivery and Therapeutics 8, no. 5 (2018): 50–55. http://dx.doi.org/10.22270/jddt.v8i5.1888.

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The convenience of administration and improved patient compliance are important in the design of oral drug delivery system which remains the preferred route of drug delivery inspite of various disadvantages. Fast disintegrating tablets (FDTs) have received ever-increasing demand during the last decade, and the field has become a rapidly growing area in the pharmaceutical industry. The popularity and usefulness of the formulation resulted in development of several FDT technologies. These techniques render the disintegration of tablet rapidly and dissolve in mouth in five seconds without chewing

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6

Abdul Qadir, Bhavana Singh, Deepika Joshi, and Nidhi Semwal. "Fast dissolving tablet: An updated review." World Journal of Biology Pharmacy and Health Sciences 11, no. 3 (2022): 052–59. http://dx.doi.org/10.30574/wjbphs.2022.11.3.0135.

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Improved patient management and patient tracking are essential to the development of an oral drug delivery system that remains a popular drug delivery route despite various maladies. Fast-dispersing pills (FDTs) have found growing demand over the past decade, and the field has become a fast-growing area in the pharmaceutical industry. The popularity and usefulness of the construction has led to the development of many FDT technologies. These are ways to make the tablet dissolve faster and spill in the mouth for five seconds without chewing and the need for beneficial water especially for child

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7

Ashutosh, Sharma, Bansal Mayank, and Sweta. "A Review on Fast Dissolving Tablet." International Journal of Current Pharmaceutical Review and Research 15, no. 04 (2023): 215–19. https://doi.org/10.5281/zenodo.12635965.

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AbstractThe convenience of administration and improved patient compliance are important in thedesign of oral drug delivery system which remains the preferred route of drug delivery inspiteof various disadvantages. Fast disintegrating tablets (FDTs) have received ever- increasingdemand during the last decade, and the field has become a rapidly growing area in thepharmaceutical industry. The popularity and usefulness of the formulation resulted indevelopment of several FDT technologies. These techniques render the disintegration oftablet rapidly and dissolve in mouth in five seconds without chew

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8

Masih, Ashish, Amar Kumar, Shivam Singh, and Ajay Kumar Tiwari. "FAST DISSOLVING TABLETS: A REVIEW." International Journal of Current Pharmaceutical Research 9, no. 2 (2017): 8. http://dx.doi.org/10.22159/ijcpr.2017v9i2.17382.

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Fast dissolving tablets emerge as one of the popular and widely accepted dosage forms, especially for pediatric patients because of incomplete development of the muscular and nervous system and a case of geriatric patients suffering from Parkinson’s disorder or hand tremors. Few solid dosage forms like capsules and tablets are present days facing the problems like difficulty in swallowing (dysphagia), resulting in many incidences of non-compliance and making the therapy ineffective. Oral dosage form and oral route are the most preferred route of administration for various drugs have limitation

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9

Baijnath, Pal* Kavita Lovanshi Rita Mourya. "A Review on Fast Dissolving Tablet." International Journal of Pharmaceutical Sciences 3, no. 4 (2025): 3147–53. https://doi.org/10.5281/zenodo.15295648.

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The most common and preferred route of drug administration is through the oral route. Fast Dissolving tablets are gaining importance among novel oral drug-delivery system as they have improved patient compliance and have some additional advantages compared to other oral formulation. They are also solid unit dosage forms, which disintegrate in the mouth within a minute in the presence of saliva due to super disintegrants in the formulation. Thus this type of drug delivery helps a proper peroral administration in pediatric and geriatric population where swallowing is a matter of trouble. Various

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10

Achal, Chavan, Bharatee Chaudhary, Vivek Kumar Redasani, Pooja Bhagat, and Rutuja Mahadik. "On Overview of Fast dissolving tablet." Asian Journal of Pharmaceutical Research and Development 11, no. 3 (2023): 190–93. http://dx.doi.org/10.22270/ajprd.v11i3.1276.

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Fast dissolving tablets emerge as one of the popular and widely accepted dosage forms, especially for paediatric patients because of incomplete development of the muscular and nervous system and a case of geriatric patients suffering from Parkinson’s disorder or hand tremors. Few solid dosage forms like capsules and tablets are present days facing the problems like difficulty in swallowing (dysphagia), resulting in many incidences of non-compliance and making the therapy ineffective. Oral dosage form and oral route is the most preferred route of administration for various drugs have limitation

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11

Manish, Kumar Gupta*, Sharma Saurabh, Gupta Manish, and Sen Priya. "FORMULATION AND EVALUATION OF FAST DISSOLVING TABLETS." International Journal of Current Pharmaceutical Review and Research 13, no. 3 (2021): 13–19. https://doi.org/10.5281/zenodo.12667092.

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The convenience of administration and improved patient compliance are essential in thedesign of oral drug delivery system which remains the preferred route of drug deliveryinstead of various limitations. Fast disintegrating tablets (FDTs) have gained ever-increasingdemand during the last decade, and the field has become a rapidly growing area in thepharmaceutical industry. The popularity and usefulness of the formulation resulted indevelopment of several FDT technologies. These techniques give the disintegration of tabletrapidly and dissolve in mouth within one-minute seconds without chewing a

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12

Priyanka Raj G, Bhavya G, Harsha Vardhana M G, and Jashwanth Gowda H U. "A Review of Formulation Techniques and Evaluation Parameters of Fast Dissolving Tablets." Journal of Pharma Insights and Research 2, no. 4 (2024): 212–17. http://dx.doi.org/10.69613/vx91cb41.

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Fast dissolving tablets (FDTs) have gained significant popularity as a convenient and patient-friendly dosage form, particularly beneficial for pediatric, geriatric, and patients with swallowing difficulties. These tablets are formulated to disintegrate or dissolve rapidly in the oral cavity, eliminating the need for water and enhancing patient compliance. This review article provides a comprehensive overview of FDTs, covering various aspects such as their definition, ideal characteristics, advantages, and formulation techniques. The manufacturing methods employed in the development of FDTs ar

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13

Harish, Kokate* Dnyaneshwar Khade Vrushali Nikhade. "Fast Disintegrating Tablets: A Review on Novel Drug Delivery System." International Journal of Pharmaceutical Sciences 3, no. 6 (2025): 56–70. https://doi.org/10.5281/zenodo.15569265.

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Fast Disintegrating Tablets (FDTs) are a promising class of oral drug delivery  tablets that dissolve or disintegrate quickly in saliva, offering a practical and patient-friendly alternative for various populations. These tablets dissolve quickly in the buccal cavity, allowing direct absorption through the mucosa, ensuring prompt therapeutic effects. They have advantages such as improved tongue feel, ease of administration, accurate dose, and comfort for bedridden or mobile patients. However, they also have drawbacks like brittleness, hygroscopicity, mechanical strength, and unpleasant sc

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14

Obaidat, Aiman, та Rana Obaidat. "Development and evaluation of fast-dissolving tablets of meloxicam-β-cyclodextrin complex prepared by direct compression". Acta Pharmaceutica 61, № 1 (2011): 83–91. http://dx.doi.org/10.2478/v10007-011-0005-7.

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Development and evaluation of fast-dissolving tablets of meloxicam-β-cyclodextrin complex prepared by direct compressionThe aim of this study was to prepare fast-dissolving tablets of meloxicam after its complexation with β-cyclodextrin (β-CD) and to investigate the effect of using different superdisintegrants on the disintegration and release of meloxicam from the tablets. A complex of meloxicam with β-CD was prepared by spray drying and then compressed in the form of tablets utilizing the direct compression technique. Three superdisintegrants were employed at various levels - sodium starch g

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Shirsand, SB, RT Gumate, V. Jonathan, and Shailashri. "Novel Co-processed Spray Dried Super Disintegrants Designing of Fast Dissolving Tablets Using." Dhaka University Journal of Pharmaceutical Sciences 15, no. 2 (2017): 167–72. http://dx.doi.org/10.3329/dujps.v15i2.30933.

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In the present study, novel co-processed superdisintegrants were developed by spray drying method using microcrystalline cellulose and mannitol in different ratios (1:1, 1:2 and 1:3) for use in the fast dissolving tablet formulations. The developed excipients were evaluated for angle of repose, Carrs index and Hausners ratio in comparison with physical mixture of superdisintegrants. The angle of repose of the developed excipients was found to be < 30o, Carrs index in the range of 9-15 % and Hausners ratio in the range of 1.12-1.16. Fast dissolving tablets of glibenclamide were prepared

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16

Gaurav, Magar Dr. A. V. Chandewar Dr. M. A. Channawar Satyam Pendor Ashwini Warankar. "Studies On Various Techniques Used for Masking the Bitterness of Drug and Formulation Development." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 3223–38. https://doi.org/10.5281/zenodo.15464093.

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The aim of the study was to mask the bitterness of Valsartan by various taste masking techniques. Quasi- emulsion solvent diffusion method, Inclusion complexation and spray drying these methods were used. Eudragit RS 100 and Ethyl Cellulose were used in 1:1, 1:1.5 and 1:2 ratios to create taste masked microsponges using Quasi- emulsion solvent diffusion method. Kneading method was used to formulate Inclusion complexes. β- Cyclodextrin was used as complexing agent. Various ratios of drug and β- Cyclodextrin were tried for taste masking.  Spray drying method was attempted to make

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17

Aly, Adel M., Khaled M. Al-Akhali, Hesham Alrefaey та Mahmoud A. Shaker. "Formulation and Evaluation of Fast Dissolving Gliclazide Tablets by Complexation with Hydroxypropyl-β-Cyclodextrin". International Journal of Pharmaceutical Sciences and Nanotechnology 7, № 1 (2014): 2399–405. http://dx.doi.org/10.37285/ijpsn.2014.7.1.13.

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 Gliclazide (GZ) is practically insoluble in water and its bioavailability is limited by dissolution rate. The aim of the present study was to enhance the dissolution rate and bioavailability of GZ by complexation with hydroxypropyl (HP)-β-cyclodextrin (CD) applying three different methods; physical mixing, kneading technique and spray drying technique. Also, to evaluate the dissolution rate and the hypoglycemic effect of the prepared complexes, in comparison with the GZ market product (Glizide tablets) in Saudi market. The produced complexes were characterized and evaluated using Differ

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18

Rathod, S., M. Phansekar, A. Bhagwan, and G. Surve. "A REVIEW ON MOUTH DISSOLVING TABLETS." INDIAN DRUGS 50, no. 11 (2013): 5–14. http://dx.doi.org/10.53879/id.50.11.p0005.

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Mouth Dissolving Tablets (MDTs) have received ever-increasing demand during the last decade and the field has become a rapidly growing area of research in the pharmaceutical industry. Upon introduction into the mouth, these tablets dissolve or disintegrate in the mouth in the absence of additional water for easy administration of active pharmaceutical ingredients. The popularity and usefulness of the formulation resulted in development of several MDT technologies. This review describes various formulations and technologies developed to achieve fast dissolution/dispersion of tablets in the oral

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19

Iqbal, Sonia, Hanasul Hanan, Afshan Maqbool, and Nasra Munawar. "A review on orodispersible drug delivery system." Journal of Contemporary Pharmacy 7, no. 1 (2023): 24–31. http://dx.doi.org/10.56770/jcp2023714.

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The future of drug delivery holds great promise for orally dispersible dose formulations, which make application simple since no water requirement as compared to conventional solid dosage forms which requires significant volumes of fluids for administration. The objective for development of ODF provides a substitute for pills, syrups, and tablets in treating vomiting as well as nausea, particularly in children. On the basis of transdermal patch delivery system, a novel oral films drug delivery has been introduced. Fast dissolving films disintegrates quickly when come in contact with salivary s

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Iqbal, Sonia, Hanasul Hanan, Afshan Maqbool, and Nasra Munawar. "A review on orodispersible drug delivery system." Journal of Contemporary Pharmacy 7, no. 1 (2023): 24–31. http://dx.doi.org/10.56770/jcp.2023714.

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The future of drug delivery holds great promise for orally dispersible dose formulations, which make application simple since no water requirement as compared to conventional solid dosage forms which requires significant volumes of fluids for administration. The objective for development of ODF provides a substitute for pills, syrups, and tablets in treating vomiting as well as nausea, particularly in children. On the basis of transdermal patch delivery system, a novel oral films drug delivery has been introduced. Fast dissolving films disintegrates quickly when come in contact with salivary s

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21

AlirezaVatanara, Ramezani Vahid, Ghasemian Elham, and Parvizi Mahsa. "Spray drying of nanoparticles to form fast dissolving glipizide." Asian Journal of Pharmaceutics 9, no. 3 (2015): 213. http://dx.doi.org/10.4103/0973-8398.160319.

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22

Poddar, Shives. "RAPID DISSOLUTION: DEVELOPMENT AND ASSESSMENT OF A NOVEL DRUG FORMULATION." American Journal of Medical Sciences and Pharmaceutical Research 06, no. 05 (2024): 01–05. http://dx.doi.org/10.37547/tajmspr/volume06issue05-01.

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This study focuses on the development and assessment of a novel fast-dissolving drug formulation aimed at improving drug delivery efficiency and patient compliance. The formulation was designed to dissolve rapidly in the oral cavity, facilitating quick absorption and onset of action. Through a systematic approach, the formulation's composition, including excipients and active pharmaceutical ingredients, was optimized to achieve rapid dissolution while maintaining stability and bioavailability. Various techniques, such as direct compression, freeze-drying, and spray drying, were explored to pro

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Ram, Swaroop, Sharma Vijay, and Ravindra N. "An Overview on Mouth Dissolving Tablets." International Journal of Current Pharmaceutical Review and Research 15, no. 04 (2023): 210–14. https://doi.org/10.5281/zenodo.12635946.

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AbstractOral route if drug delivery has been used from many decades and it is one of the mostpreferred routes of administered. Mouth dissolving tablets (MDTs) are the tablets which getsdisintegrates very quickly and release medicaments instantaneously. In the present study wehave discussed about ideal properties of MDTs along with their advantages anddisadvantages. Different types of manufacturing technique are employed such as Freezedrying, Molding, Tablet Molding, Direct Compression, Spray drying and Mass Extrusion,which are discussed below. There are many evaluation parameters like General

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Kim, Jae-Il, and Hoo-Kyun Choi. "Development of Fast Dissolving Tablet Containing Herb Extract by Freeze-Drying Technique." Journal of Pharmaceutical Investigation 40, no. 3 (2010): 161–66. http://dx.doi.org/10.4333/kps.2010.40.3.161.

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Alaei, Samaneh, Elham Ghasemian, and Alireza Vatanara. "Spray drying of cefixime nanosuspension to form stabilized and fast dissolving powder." Powder Technology 288 (January 2016): 241–48. http://dx.doi.org/10.1016/j.powtec.2015.10.051.

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Ahmed, I. S., M. M. Nafadi, and F. A. Fatahalla. "Formulation of a Fast-Dissolving Ketoprofen Tablet Using Freeze-Drying in Blisters Technique." Drug Development and Industrial Pharmacy 32, no. 4 (2006): 437–42. http://dx.doi.org/10.1080/03639040500528913.

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27

Pandian.C, Bharathkumar.M, Vasanthakumar.A, and Sreeja.P. "Oral Disintegrating Tablet: A Review." International Journal of Pharmaceuticals and Health Care Research 12, no. 4 (2024): 448–54. https://doi.org/10.61096/ijphr.v12.iss4.2024.448-454.

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Comfort of drug administration and patient compliance are important considerations in dosage form design. Strong, adaptable tablets with exceptional flavor masking and controlled release can be produced using new and emerging technology. Solid dose forms known as oral disintegrating tablets (ODTs) dissolve in the mouth in less than 60 seconds, allowing for waterless swallowing. Rapid pill disintegration results in rapid dissolving and, thus, a rapid start of action. Pediatrics, the elderly, psychotic, dysphagic, bedridden, comatose, young patients with underdeveloped neurological and muscular

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Patel, Sarvesh, Jai Narayan Mishra, and Dhaneswar Kumar Vishwakarma. "FORMULATION DEVELOPMENT AND CHARACTERIZATION OF FAST DISSOLVING TABLET OF ATENOLOL BY DIRECT COMPRESSION METHOD." International Journal of Advanced Research 9, no. 10 (2021): 1277–86. http://dx.doi.org/10.21474/ijar01/13678.

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Finally in the project work Atenolol is an anti-hypertensive drug. It has been formulated into fast dissolving tablets by direct compression method by using the Excipients like lactose, sucrose magnesium stearate, sodium lauryl and sulphate and many type super disintegrates such as crosscarmellose and sodium starch glycolate and the prepared by the tablets were evaluated for the pre-compression parameter such as angle of repose, bulk density, tapped density, % index, Hausners ratio, partition coefficients, melting points, UV spectroscopy, % assay, TLC, loss on drying and post compression param

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Laitupa, Fajriyanti Azzura, Ardhia Deasy Rosita Dewi, Christina Mumpuni Erawati, Prita Ayu Kusumawardhany, Lanny Kusuma Widjaja, and Hazrul Iswadi. "Karakterisasi Fisikokimia dan Organoleptik Tablet Effervescent Ashitaba (Angelica keiskei)." MPI (Media Pharmaceutica Indonesiana) 6, no. 1 (2024): 11–20. http://dx.doi.org/10.24123/mpi.v6i1.5648.

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Ashitaba (Angelica keiskei) merupakan tanaman yang mengandung senyawa flavonoid (kalkon) dan tanin yang dapat berperan sebagai antioksidan. Kandungan antioksidan pada ashitaba akan mudah dikonsumsi dalam bentuk sediaan tablet effervescent. Penelitian ini bertujuan untuk mengetahui formula terbaik tablet effervescent ashitaba. Tablet effervescent merupakan bentuk sediaan yang menghasilkan gelembung gas karbondioksida sebagai hasil dari reaksi kimia dalam larutan yang mengandung senyawa asam dan senyawa karbonat atau bikarbonat hingga terdapat rasa sparkly pada minuman setelah tablet larut sempu

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Pradhan, Roshan, Tuan Hiep Tran, Sung Yub Kim, et al. "Preparation and characterization of fast dissolving flurbiprofen and esomeprazole solid dispersion using spray drying technique." International Journal of Pharmaceutics 502, no. 1-2 (2016): 38–46. http://dx.doi.org/10.1016/j.ijpharm.2016.02.020.

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31

Shashank Khailkhura, Bhavana Singh, Deepika Joshi, and Nidhi Semwal. "Orally disintegrating tablet: A review." World Journal of Biology Pharmacy and Health Sciences 11, no. 3 (2022): 018–25. http://dx.doi.org/10.30574/wjbphs.2022.11.3.0124.

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Orally dispersive tablets are solid dosage forms that dissolve in the mouth in within 10 to 30 seconds, enabling waterless ingestion. The tablet dissolves quickly due to its fast breakdown, which also causes the effects to start acting quickly. ODTs can help patients with a variety of conditions, including pediatrics, geriatrics, psychosis, dysphagia, bedridden discomfort, comatose patients, young patients with undeveloped muscular and nervous systems, patients with hand tremors, and patients who travel often. It provides high stability, precise dosage, efficient manufacture, and smaller packi

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Shashank, Khailkhura, Singh Bhavana, Joshi Deepika, and Semwal Nidhi. "Orally disintegrating tablet: A review." World Journal of Biology Pharmacy and Health Sciences 11, no. 3 (2022): 018–25. https://doi.org/10.5281/zenodo.7180875.

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Orally dispersive tablets are solid dosage forms that dissolve in the mouth in within 10 to 30 seconds, enabling waterless ingestion. The tablet dissolves quickly due to its fast breakdown, which also causes the effects to start acting quickly. ODTs can help patients with a variety of conditions, including pediatrics, geriatrics, psychosis, dysphagia, bedridden discomfort, comatose patients, young patients with undeveloped muscular and nervous systems, patients with hand tremors, and patients who travel often. It provides high stability, precise dosage, efficient manufacture, and smaller packi

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Reddy, Dr D. RamaBrahma, Dr Ch N. V. S. Mastan Rao, K. John Abhi K. John Abhi, et al. "An Overview on Immediate Drug Release of Pravastatin Drug." International Journal of Pharmaceutical Research and Applications 10, no. 1 (2025): 847–50. https://doi.org/10.35629/4494-1001847850.

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The objective of this research was to formulate fast dissolving tablets of Pravastatin sodium that disintegrate in the oral cavity upon contact with saliva and there by improve therapeutic efficacy. Pravastatin sodium is used for the treatment of myocardial infarction. Fast dissolving tablets of pravastatin sodium were prepared by direct compression method using three different superdisintegrants-Sodium starch glycollate, Croscarmellose sodium and Crosspovidone (2%, 4% and 6%) and three different diluents (mannitol and spray dried lactose) in different concentrations. Eighteen formulations wer

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Baby, Lynthong1* Fathima Thafheema2 M. Mallikarjuna Gowda3. "Fast-Melt Tablets: A New Era On Brand-New Drug Delivery System And Its Technology." International Journal in Pharmaceutical Sciences 2, no. 10 (2024): 1108–18. https://doi.org/10.5281/zenodo.13955749.

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The predominant method of medicine delivery is still oral. Novel technologies with greater performance, patient compliance, and enhanced quality have evolved in the recent past. Fast-melt tablets are specifically made to dissolve in saliva very quickly within a few seconds when placed on the tongue without the need for water. Super disintegrants are added to FMT formulations to speed up a tablet's breakdown in the mouth. The technology utilized in the production of fast-melt tablets (FMTs) can be classified as either proprietary or conventional. Conventional methods such as freeze drying, tabl

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35

Pittman, David W., Alexandra M. Brantly, Alexandra L. Drobonick, et al. "The Palatability of Lopinavir and Ritonavir Delivered by an Innovative Freeze-Dried Fast-Dissolving Tablet Formulation." AIDS Research and Treatment 2018 (2018): 1–13. http://dx.doi.org/10.1155/2018/5908167.

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Negative hedonic sensory qualities of HIV antiretroviral drugs often reduce patient adherence particularly in pediatric populations requiring oral consumption. This study examines the palatability of an innovative delivery mechanism utilizing a freeze-drying-in-blister approach to create fast-dissolving tablets (FDTs) containing a fixed-dose combination of lopinavir and ritonavir (LPV/r). Consumption patterns of solutions during brief-access and long-term testing and baby foodstuff consumption were analyzed to evaluate the orosensory detection and avoidance of placebo FDTs containing no LPV/r

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Prajapati, Vinitbhai*1 Himanshu Sharma2 Sagar Patra3 Sahilahmad Makarani3 Mahendrakumar Dubey1. "A Contemporary Approach to The Medicate Conveyane Through Orodispersible Tablets." International Journal of Scientific Research and Technology 1, no. 12 (2024): 29–40. https://doi.org/10.5281/zenodo.14285188.

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The development of dosage forms that are easy to manufacture and administer, as well as rapid release and increased bioavailability, have led to new drug delivery systems. To achieve the desired result, drugs must be delivered to the site of action at a speed and concentration that maximizes therapeutic benefits and minimizes side effects. The most popular and efficient way of drug administration is oral. Recently, many medicinal products have been released in the market. The use of lyophilizers and oral tablets or films have expanded treatment options. Both children and adults can benefit fro

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Roy, Harekrishna, Sisir Nandi, Ungarala Pavani, Uppuluri Lakshmi, Tamma Saicharan Reddy, and Damarla Venkata Sri Gayatri. "Optimization and Quality by Design Approach for Piroxicam Fast Dissolving Tablet Formulations Using Box-Behnken Design." Current Drug Therapy 15, no. 2 (2020): 152–65. http://dx.doi.org/10.2174/1574885514666190409102614.

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Background: The present study deals with the formulation and optimization of piroxicam fast dissolving tablets and analyzes the impact of an independent variable while selecting the optimized formulation utilizing Quality by Design (QbD) and Box-Behnken Design (BBD). Methods: Seventeen formulations were prepared by direct compression technique by altering the proportion of cross carmellose sodium, spray dried lactose and hydro propyl methyl cellulose (HPMC K4M). The BBD statistical technique was used to optimize formulations and correlate the relationship among all the variables. Also, the pow

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Šimková, Kateřina, Berndt Joost, and Georgios Imanidis. "Production of fast-dissolving low-density powders for improved lung deposition by spray drying of a nanosuspension." European Journal of Pharmaceutics and Biopharmaceutics 146 (January 2020): 19–31. http://dx.doi.org/10.1016/j.ejpb.2019.11.003.

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Azad, Mohammad, Colby Arteaga, Beshoy Abdelmalek, Rajesh Davé, and Ecevit Bilgili. "Spray drying of drug-swellable dispersant suspensions for preparation of fast-dissolving, high drug-loaded, surfactant-free nanocomposites." Drug Development and Industrial Pharmacy 41, no. 10 (2014): 1617–31. http://dx.doi.org/10.3109/03639045.2014.976574.

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Dingalwar, Achal, Anil Pethe, Tanmay Kopare, and Umesh Telrandhe. "An Overview of the Components, Techniques, and Innovation Used for Fast-Dissolving Films." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 14, no. 03 (2024): 1853–62. http://dx.doi.org/10.25258/ijddt.14.3.84.

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Fast-dissolving films (FDFs) stand as a cornerstone in modern pharmaceutical innovation, heralded for their unrivaled convenience, patient adherence, and the swift onset of action. Within the realm of this paper lies a meticulous exploration of FDFs, delving deep into their intricate formulation intricacies, manufacturing methodologies, and diverse therapeutic applications. The formulation journey traverses the meticulous selection of film-forming polymers, plasticizers, taste-masking agents, and active pharmaceutical ingredients (APIs), each element meticulously calibrated to achieve optimal

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Bhakare, Shweta, and Ajay G. Pise. "Deep Insights into the Developmental Progress of Orally Disintegrating Tablet Formulation, Techniques, and Products: A Comprehensive Review." International Journal of Medical & Pharmaceutical Sciences 12, no. 05 (2022): 17–22. http://dx.doi.org/10.31782/ijmps.2022.12503.

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When it comes to the design of dosage forms, the ease of medication administration and patient compliance are given significant consideration. Recently developed and emerging technologies may be used to make durable, multifunctional tablets that have exceptional flavor masking properties and controlled release. It is possible to consume orally disintegrating tablets (ODTs) without drinking water since they break down in the mouth in less than 60 seconds and dissolve completely in the mouth. Rapid disintegration of the tablet results in rapid dissolving and, as a result, rapid beginning of acti

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Serim, Tuğrul Mert, Jan Kožák, Annika Rautenberg, Ayşe Nurten Özdemir, Yann Pellequer, and Alf Lamprecht. "Spray Freeze Dried Lyospheres® for Nasal Administration of Insulin." Pharmaceutics 13, no. 6 (2021): 852. http://dx.doi.org/10.3390/pharmaceutics13060852.

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Pharmacologically active macromolecules, such as peptides, are still a major challenge in terms of designing a delivery system for their transport across absorption barriers and at the same time provide sufficiently high long-term stability. Spray freeze dried (SFD) lyospheres® are proposed here as an alternative for the preparation of fast dissolving porous particles for nasal administration of insulin. Insulin solutions containing mannitol and polyvinylpyrrolidone complemented with permeation enhancing excipients (sodium taurocholate or cyclodextrins) were sprayed into a cooled spray tower,

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Pawar, Harshala, Aishwarya Pawar, and Shraddha N. Bhavsar. "FAST DISINTEGRATING TABLETS - A NEW ERA IN NOVEL DRUG DELIVERY SYSTEM." International Journal of Advanced Research 10, no. 01 (2022): 94–109. http://dx.doi.org/10.21474/ijar01/14018.

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Among all dosage forms, fast-Disintegrating tablets are one of the most commonly used dosage forms, especially in children, because their nervous system and muscular system are not well developed compared to them in adults. and in adult patients with Parkinsons disease or hand tremors. Some fixed dosage forms, such as capsules and tablets, now have difficulty swallowing (dysphagia), which results in many cases of non-compliance and renders therapy ineffective. The most preferred routes of administration for various drugs are oral dosage forms and the oral route with specific limitations such a

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Sreeharsha, Nagaraja, Nimbagal Raghavendra Naveen, Posina Anitha, et al. "Development of Nanocrystal Compressed Minitablets for Chronotherapeutic Drug Delivery." Pharmaceuticals 15, no. 3 (2022): 311. http://dx.doi.org/10.3390/ph15030311.

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The present work aimed to develop a chronotherapeutic system of valsartan (VS) using nanocrystal formulation to improve dissolution. VS nanocrystals (VS-NC) were fabricated using modified anti-solvent precipitation by employing a Box–Behnken design to optimize various process variables. Based on the desirability approach, a formulation containing 2.5% poloxamer, a freezing temperature of −25 °C, and 24 h of freeze-drying time can fulfill the optimized formulation’s requirements to result in a particle size of 219.68 nm, 0.201 polydispersity index, and zeta potential of −38.26 mV. Optimized VS-

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Mr. Sushant Shinde, Miss. Sakshi Shinde, and Mr. Dnyaneshwar Landage. "A Review on Fast Dissolving Tablet." International Journal of Advanced Research in Science, Communication and Technology, May 16, 2024, 533–42. http://dx.doi.org/10.48175/ijarsct-18280.

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Drug delivery systems play a crucial role in the effective administration of medications. Solid dosage forms, such as tablets and capsules, are widely accepted due to their ease of administration, accurate dosage, and patient compliance. However, the challenge lies in developing an ideal drug delivery system that ensures the right rate and concentration of drug delivery to achieve maximum therapeutic effect and minimal adverse effects. Fast dissolving tablets (FDTs) have emerged as an alternative to conventional dosage forms, especially for paediatric, geriatric, and uncooperative patients, as

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Jeevandeep, Mishra, Shiv Hardenia Dr., and D.K. Jain Dr. "A Review of Formulation Technology for Recent Advancements in Fast Dissolving Tablets." June 16, 2023. https://doi.org/10.5281/zenodo.8047479.

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The design of the oral drug delivery system, which is still the dominant method of drug delivery despite a number of drawbacks, must take into account the ease of administration and increased patient compliance. Due to the insufficient development of the muscular and neurological systems in children, as well as cases of elderly individuals with Parkinson's disease or hand tremors, fast-dissolving tablets have become one of the most well-liked and widely recognised dose forms. Today's solid dosage forms, such as capsules and tablets, are dealing with issues like dysphagia, which leads t

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Thakur, Mansi, Isha Sharma, Michi Moda, and Neha Sharma. "Fast Dissolving Films: A Review." Asian Journal of Research in Pharmaceutical Sciences, August 26, 2023, 211–17. http://dx.doi.org/10.52711/2231-5659.2023.00037.

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Fast dissolving films for oral administration were a novel treatment option for individuals who had trouble swallowing pills or tablets. Hydrophilic polymers are used to create a film that quickly dissolves on the tongue. Upto 50-60% of all dosage forms, the traditional dosage forms (tablet and capsule) are widely accepted. For condition such as trigeminal neuralgia, Meniere’s disease and addiction, any buccal administration solutions have been commercialized or are being suggested. The type of drug delivery system known as an orally fast dissolving film dissolves or disintegrates in the oral

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Singh, Soumya. "Is Fast Dissolving Tablets Satisfy Its Role: A Brief Discussion." Int. Jour. of Pharmamedix India 2, no. 2 (2025). https://doi.org/10.71152/vjerdj61.

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It is very well known fact that a drug can be administered through many different routes so as to produce a systemic pharmacological effect. The route of administration is considered as the path by which a drug is taken into the body for the treatment of various diseases and disorders. The main route of administrating a drug is the oral route which is the oldest and most commonly used because of its ease of administration, self-medication and avoidance of pain as compared to parental route. Oral drug delivery remains the preferred route of drug delivery. Despite of the tremendous advancement i

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Yojana, Kurhade* Deepti Phadtare. "Review On Fast Dissolving Tablets - A New Era in Novel Drug Delivery System." June 15, 2023. https://doi.org/10.5281/zenodo.8040512.

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Among all dosage forms, fast-Dissolving tablets are one of the most commonly used dosage forms, especially in children, because their nervous system and muscular system are not well developed compared to them. in adults. and in adult patients with Parkinson's disease or hand tremors. Some fixed dosage forms, such as capsules and tablets, now have difficulty swallowing (dysphagia), which results in many cases of non-compliance and renders therapy ineffective. The most preferred routes of administration for various drugs are oral dosage forms and the oral route with specific limitations such

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S*, Kiran, Khemchand S, Shivraj J, and Dhananjay P. "Comprehensive Study on Pharmaceutical Delivery: Mouth Dissolving Tablets." Open Access Journal of Pharmaceutical Research 8, no. 3 (2024). http://dx.doi.org/10.23880/oajpr-16000319.

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Fast-disintegrating tablets are one of the most often utilized dose forms available, particularly for youngsters whose nervous and muscular systems are still developing in comparison to adults. in grownups. and in adult individuals who have hand tremors or Parkinson's disease. Due to swallowing difficulties caused by dysphagia, many fixed dose forms, including tablets and capsules, no longer comply with prescribed dosages, making therapy ineffective. Oral dosage forms and the oral route with certain constraints, such as first-pass liver metabolism, mental patients, at-risk patients, and non-co

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