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1

Fanti, Giulia, Peter Kairouz, Sewoong Oh, and Pramod Viswanath. "Spy vs. Spy." ACM SIGMETRICS Performance Evaluation Review 43, no. 1 (June 24, 2015): 271–84. http://dx.doi.org/10.1145/2796314.2745866.

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2

Waldner, Liz. "Spy vs. Spy, and: Let There Be Light." Colorado Review 37, no. 1 (2010): 141–42. http://dx.doi.org/10.1353/col.2010.0083.

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3

Scott, Cord A. "Cold War politics, Cuba, and Spy vs. Spy." Journal of Graphic Novels and Comics 11, no. 3 (March 21, 2019): 315–24. http://dx.doi.org/10.1080/21504857.2019.1582545.

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4

Ng, K. W. "Spy vs. Spy: Recruiting Stem Cells to the War on Cancer." Science Translational Medicine 2, no. 47 (September 1, 2010): 47ec137. http://dx.doi.org/10.1126/scitranslmed.3001625.

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5

de Castro, Guilherme Vieira, and Alessio Ciulli. "Spy vs. spy: selecting the best reporter for 19F NMR competition experiments." Chemical Communications 55, no. 10 (2019): 1482–85. http://dx.doi.org/10.1039/c8cc09790a.

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6

CARABAS, TEODORA. "Tales Calculated to Drive You MAD": The Debunking of Spies, Superheroes, and Cold War Rhetoric in Mad Magazine's "SPY vs SPY"." Journal of Popular Culture 40, no. 1 (February 2007): 4–24. http://dx.doi.org/10.1111/j.1540-5931.2007.00351.x.

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7

Norets, Maksim, Vitaliy Lubeyev, and Svetlana Lubeyeva. "The English spy novels of the “cold war” period and the concept “we” vs “they” as their basis." SHS Web of Conferences 69 (2019): 00084. http://dx.doi.org/10.1051/shsconf/20196900084.

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This investigation is dedicated to the analysis of the works of the British authors of the spy novels of the “Cold War” period, who have formed a spy novel as the separate genre. In the work the investigator takes the attempt to analyse the concept “we” vs “they” as the basic structure of the plot forming in the context of historical events taking into account the belonging of the author to the secret service. The attention of the author of the investigation is focused on the new forms of realization of the plot line and the modification of the protagonist and antagonist.
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8

Vidula, Neelima, Christina Yau, and Hope S. Rugo. "Trop2 gene expression (Trop2e) in primary breast cancer (BC): Correlations with clinical and tumor characteristics." Journal of Clinical Oncology 35, no. 15_suppl (May 20, 2017): 1075. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.1075.

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1075 Background: Trophoblast antigen 2 (Trop2) is a glycoprotein expressed by many cancers. A phase I study of the trop2 antibody drug conjugate (ADC) IMMU-132 has shown promising activity in triple negative (TN) BC. We studied associations of primary BC trop2e with clinical characteristics, outcomes, and selected genes in publically available databases. Methods: Trop2e was evaluated with microarray data from the neoadjuvant I-SPY 1 (n=149), METABRIC (n=1992) & TCGA (n=817) databases. Associations with clinical features were assessed with the Kruskal-Wallis test (all). Correlations with chemotherapy response were evaluated with the Wilcoxon rank sum test (I-SPY 1) & with recurrence free survival (RFS) by the Cox proportional hazard model (I-SPY 1 & METABRIC). Pearson correlations were used to study associations between trop2e & selected genes (all). Results: In all 3 datasets, trop2 was detectable and had a wide range of expression in all BC subtypes. In I-SPY 1, trop2e did not vary by hormone receptor (HR) & HER2 or intrinsic subtype; in METABRIC & TCGA trop2e was lower in HER2+ than HR+/HER2- & TNBC (METABRIC p=0.03, TCGA p=0.007) & in HER2+ enriched and luminal B BC (p < 0.001, METABRIC & TCGA). Trop2e was higher in grade I vs. II/III BC in METABRIC (p < 0.001). No association with chemotherapy response was seen (I-SPY 1) or with RFS (I-SPY 1 & METABRIC). The table below shows significant (p<0.05) gene correlations with trop2e in ≥2 datasets. Conclusions: Trop2e is seen in all BC subtypes, particularly luminal A and TNBC. Trop2e correlates with the expression of genes involved in cell epithelial transformation, adhesion, and proliferation and inversely with immune genes, which may contribute to tumor growth. These findings support the use of trop 2 directed ADC in all BC subtypes. [Table: see text]
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Lethier, Pierre, and Clara Laurent. "Marthe Richard vs. Mata Hari: The (De)mythologizing of a French Spy." Studies in French Cinema 9, no. 1 (March 2009): 63–73. http://dx.doi.org/10.1386/sfc.9.1.63_1.

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10

Hindersmann, Jost. "Nordic noir vs. spies in the cold: The reception of Scandinavian TV and film adaptations in Germany." Journal of Scandinavian Cinema 9, no. 3 (September 1, 2019): 277–87. http://dx.doi.org/10.1386/jsca_00004_1.

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Scandinavian crime novels and their adaptations as TV dramas and films, commonly known as Nordic noir, are very popular in Germany. Nordic noir often has a political content and when spies appear, they are usually portrayed negatively. Scandinavian spy novels and their adaptations, on the other hand – with the exception of Guillou’s Coq Rouge series – never reached wide audiences in Germany.
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11

EDGAR, WILLIAM. "Eric Metaxas. Bonhoeffer: Pastor, Martyr, Prophet, Spy: A Righteous Gentile vs. the Third Reich. Nashville: Nelson, 2010." Unio Cum Christo 1, no. 1 (October 1, 2015): 127. http://dx.doi.org/10.35285/ucc1.1-2.2015.rev6.

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12

DeMichele, A., L. Dunn, P. Gimotty, C. Livasy, C. Perou, L. Carey, and L. Esserman. "Loss of p27 expression and response to neoadjuvant chemotherapy: Results from the I-SPY Trial (CALGB150007/150012, ACRIN6657)." Journal of Clinical Oncology 27, no. 15_suppl (May 20, 2009): 11091. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.11091.

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11091 Background: Loss of expression of the cyclin-dependent kinase (cdk) inhibitor p27 has been associated with decreased survival among patients receiving adjuvant chemotherapy. The I-SPY Trial is a multicenter study of locally advanced breast cancer in which pretreatment tumor biopsies were obtained prior to the administration of anthracycline and taxane-based neoadjuvant therapy, and serial MRIs were performed to assess response to treatment. The aim of this study was to determine if loss of tumor p27 expression was associated with response to cytotoxic therapy. Methods: Eligible patients had biopsy-confirmed primary breast cancer measuring at least 3 cm. Immunohistochemistry for p27 was performed centrally on pretreatment core samples using rabbit anti-p27 (Upstate Cell Signaling #06–445). Nuclear p27 was classified as absent (no staining), low (1–50% staining) or normal (>50% staining). Following completion of chemotherapy, post-surgical excision/mastectomy cases were reviewed centrally to determine response to therapy including residual cancer burden (RCB) and pathologic complete response (pCR) rate. Exact Chi2 was used to compare proportions. Results: Pretreatment samples from 164 of 237 enrolled patients demonstrated that p27 expression was absent in 55 (33%), low in 96 (58%) and normal in 14 (8%). P27 loss was not associated with patient age. Compared to normal p27 expression, absent p27 was significantly associated with ER negativity (48% vs. 14%; p=0.03), PR negativity (59% vs. 21%; p=0.03), Her2 overexpression (28% vs. 14%; p=0.017) and basal molecular subtype (29% vs. 13%). The proportion of patients with p27 loss (absent or low) was higher for those with high Ki-67 expression compared to low/mod expression (98% compare to 88%) and lower for grade 1 (72% vs 92%) compared to grade 2/3 tumors (p=0.071 and p=0.090, respectively). Low or absent p27 was not associated with response to therapy as measured by pCR, RCB or change in tumor diameter by MRI. Conclusions: p27 loss in this neoadjuvant patient population was associated with aggressive tumor features, but not predictive of response to cytotoxic therapy. These findings suggest that the poor prognosis associated with loss of p27 is not due to relative chemotherapy resistance. No significant financial relationships to disclose.
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13

Lin, C., D. Moore, A. DeMichele, D. Ollila, L. Montgomery, M. Liu, H. Krontiras, R. Gomez, and L. Esserman. "Detection of locally advanced breast cancer in the I-SPY TRIAL (CALGB 150007/150012, ACRIN 6657) in the interval between routine screening." Journal of Clinical Oncology 27, no. 15_suppl (May 20, 2009): 1503. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.1503.

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1503 Background: It is assumed that most locally advanced breast cancers (LABC) could be detected at an earlier stage with routine screening. However, LABCs may present between screens as interval cancers (IC). ICs present at an earlier age, with higher grade, larger size, and are associated with lower survival, compared to screen-detected cancers (SDC), and comprise 17% of cancers from population-based screening programs. We evaluated the screening history in patients with LABCs from the I SPY TRIAL, to determine the frequency of screening and ICs. Methods: Of 221 pts enrolled in the I-SPY TRIAL, a multisite neoadjuvant study for women with LABCs > 3cm in size, screening history and presentation were retrospectively collected for 154. Two groups, screened (S), defined as a mammogram within 2 years, or non screened (NS), previous mammogram more than 2 years prior, were evaluated (Table). The frequency of ICs at 1 and 2 years was determined in S pts. Frequency of mammographically occult (MO) tumors was determined for all. Results: Of the total, 99 (64%) and 55 (36%) were NS and S, respectively. Mean tumor size for all pts was 6.7cm. Only 11 (20%) of S pts were SDCs and 44 (80%) were ICs, with 24 (63%) diagnosed within 1 year and 14 (37%) between 1 and 2 yrs of their last normal mammogram. 24 (24%) NS patients were younger than the recommended screening age of 40; in the remaining 75 pts, 9 (12%) were MO. Only 20% of IC tumors were MO. ICs were of higher grade (44% vs 11% grade III), and tumor size (7.0cm vs 4.4cm) than their SDC counterparts. 80% of cancers detected in I SPY were NKI70 gene test poor prognosis. Relationship to breast density and subtype is currently being assessed. Conclusions: Women presenting with LABCs have a high likelihood (80%) of an IC. This suggests that the growth rate of LABCs precludes early detection by conventional screening. Understanding the biology of ICs will be important to develop better strategies for prevention and early detection. [Table: see text] No significant financial relationships to disclose.
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14

Li, Jiali, Christina Yau, Michael Campbell, Laura Esserman, John W. Park, and Hope S. Rugo. "Correlation of receptor activator of nuclear factor kappa b (RANK) expression in breast cancer (BC) at the time of diagnosis with recurrence-free survival (RFS) and risk of bone-dominant metastases (BDM) in the I-SPY 1 trial (CALGB 150007/150012; ACRIN 6657)." Journal of Clinical Oncology 30, no. 27_suppl (September 20, 2012): 2. http://dx.doi.org/10.1200/jco.2012.30.27_suppl.2.

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2 Background: RANK is a tumor necrosis factor receptor family protein that is critical to bone turnover. The ligand to RANK (RANKL) can induce metastases from RANK-expressing tumor cells, and treatment with a RANKL inhibitor can reduce BC metastases (mets) in pre-clinical models and there is an FDA approved drug that targets RANKL. Osteoprotegerin (OPG) is a RANKL decoy receptor that blocks the interaction of RANK/RANKL. I-SPY 1 was a multicenter neoadjuvant trial with well annotated gene expression data and detailed clinical outcomes; we studied the impact of RANK expression on both RFS and BDM. Methods: OPG/RANK/RANKL pathway expression in core biopsies was evaluated at diagnosis in patients (pts) on I-SPY 1, then correlated with ER, intrinsic subtype, stage, response to chemotherapy, site of mets and RFS using the student t-test. Results: Gene arrays were performed on pretreatment tumor from 221 pts; 149 pts have available data with n being ER+. At a median follow-up of 3.5 yrs, 36 pts developed recurrence; 13 pts had BDM, 15 had non-bone mets (NBDM), and 8 pts were not evaluable. RANK, but not OPG or RANKL, was more highly expressed in ER- vs ER+ tumors (p=0.04) and in basal vs luminal A/B subtypes (p= 0.04), but no difference in expression based on tumor grade, node status or response to chemotherapy. Higher (>50%) RANK and lower (<50%) OPG expression correlated with worse RFS (p=0.03). Pts who developed BDM had higher expression of RANK, but not RANKL or OPG compared those with NBDM (p=0.05). After adjusting for ER and intrinsic subtypes, RANK expression was even more significantly correlated with risk for BDM (p=0.004). Conclusions: Higher RANK and lower OPG expression in primary tumor tissue correlates with poor RFS, and high RANK expression is associated with increased risk for BDM. These data suggests that targeting the OPG/RANK/RANKL pathway could be a promising strategy in preventing BDM in pts with high risk BC.
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15

Kang, Jamie, and Tim Leung. "Asynchronous ADRs: overnight vs intraday returns and trading strategies." Studies in Economics and Finance 34, no. 4 (October 2, 2017): 580–96. http://dx.doi.org/10.1108/sef-10-2016-0254.

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Purpose The purpose of this study is to analyze the overnight and intraday returns of the most traded American Depositary Receipts (ADRs) of Asian companies, understand the different levels of volatilities realized in these asynchronous markets and develop trading strategies based on empirical findings. Design/methodology/approach This study presents an empirical analysis on the overnight and intraday returns of Asian ADRs. The authors propose a measure to quantify the relative contributions of the intraday and overnight returns to the ADR's total volatility. Furthermore, the return difference between S&P500 index and each ADR is fitted to an Ornstein–Uhlenbeck model via maximum-likelihood estimation. Findings This study finds that ADRs' overnight returns are more volatile, whereas the intraday returns are significantly more strongly correlated with the US market returns. The return spreads between the S&P500 and ADRs are found to be a mean-reverting time series and motivate a pairs trading strategy. Research limitations/implications The methodology used in this study is not limited to Asian ADRs and can be adapted to analyze the overnight and intraday returns of other non-Asian ADRs and stocks. Practical implications Investors should be aware of the overnight price fluctuations while intraday traders may consider strategies that capture the mean-reverting return spread between an ADR (or an Exchange-Traded Funds [ETF] of Asian stocks) and the S&P500 index ETF (SPY). Social implications ADRs are among the most popular securities for investing in foreign (non-US) companies. The total global investments in ADRs are estimated to be close to US$1tn. Understanding the risks of ADRs is important to not only individual/institutional investors but also regulators. Originality/value This study provides a new measure to quantify and compare the relative contributions of volatility by overnight and intraday returns. Optimized pairs trading strategies involving ADRs and ETFs are developed and backtested.
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Jung, Byung Joon. "Lyom Dongjin, Spy of Kwantung Army Kempeitai vs. Kim Hyuk, Independence Fighter: Cross Rancor of Alumni of Luoyang Military Academy and Origins of the White Shirts Society." Critical Review of History 135 (May 31, 2021): 289–331. http://dx.doi.org/10.38080/crh.2021.05.135.289.

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17

Ryu, Min-Hee, Eishi Baba, Kyung Hee Lee, Narikazu Boku, Young Iee Park, Ichinosuke Hyodo, Byung-Ho Nam, et al. "Phase III trial of a 3-weekly versus 5-weekly schedule of S-1 plus cisplatin (SP) combination chemotherapy for first-line treatment of advanced gastric cancer (AGC): SOS study." Journal of Clinical Oncology 31, no. 18_suppl (June 20, 2013): LBA4024. http://dx.doi.org/10.1200/jco.2013.31.18_suppl.lba4024.

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LBA4024 Background: 5-weekly S-1 plus cisplatin (SP5: S-1 80-120 mg/body/day on D1-21, cisplatin 60 mg/m2 on D8, every 5 weeks) has become a standard first-line chemotherapy for AGC in Japan based on the SPIRITS trial (Lancet Oncol. 2008;9:215). To strengthen the low-dose intensity of cisplatin in this SP5 for greater efficacy, a 3-weekly S-1 plus cisplatin (SP3: S-1 80 mg/m2/day on D1-14, cisplatin 60 mg/m2on D1, every 3 weeks) has been developed in Korea (Cancer Chemother Pharmacol. 2008;61:837). Methods: This SOS study was a multicenter, randomized, open-label, phase III study to evaluate whether SP3 was non-inferior/superior to SP5 in terms of progression-free survival (PFS) determined by a blinded central radiology review according to RECIST v1.1. Patients (pts) with metastatic or recurrent gastric or gastroesophageal junction adenocarcinoma and with no prior chemotherapy were randomized 1:1 to receive either SP3 or SP5 until disease progression or unacceptable toxicities. Results: Between February 2009 and January 2012, a total of 625 pts were randomized from 42 sites in Korea and Japan. Median age was 59.6 years. 99% of pts had ECOG performance status 0-1. 16% of pts had prior gastrectomy. 62% of pts had measurable lesions. With a median follow-up of 34.7 months (range, 14.2-48.8) in surviving pts, SP3 was significantly noninferior and superior to SP5 in PFS (median 5.5 months vs. 4.9 months; HR 0.82, 95% CI 0.68-0.99, p=0.0418). Overall response rate (ORR) was also better with SP3 than with SP5 (60% vs. 50%, p=0.029). However, OS of both groups was equivalent (median 14.1 vs. 13.9 months; HR 0.99, 95% CI 0.81-1.21, p=0.9068). Treatment was well tolerated in both arms, while SP3 was associated with more frequent G3/4 anemia (19% vs. 9%) and neutropenia (39% vs. 9%). Dose intensity was higher in SP3 than in SP5 for both agents (median 331 vs. 317 mg/m2/week for S-1, p<0.001; median 18 vs. 12 mg/m2/week for cisplatin, p<0.001). Conclusions: SP3 was noninferior and superior to SP5 in terms of PFS and ORR. However, considering the small benefit in PFS and no difference in OS, both SP3 and SP5 can be recommended for the first-line treatment of AGC. Clinical trial information: NCT00915382.
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18

Curto, John M., and Marisa C. Kozlowski. "Chemoselective Activation of sp3 vs sp2 C–H Bonds with Pd(II)." Journal of the American Chemical Society 137, no. 1 (December 29, 2014): 18–21. http://dx.doi.org/10.1021/ja5093166.

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19

Peres, Maria, Manuela F. Almeida, Élia J. Pinto, Carla Carmona, Sara Rocha, Arlindo Guimas, Rosa Ribeiro, et al. "Implementing a Transition Program from Paediatric to Adult Services in Phenylketonuria: Results after Two Years of Follow-Up with an Adult Team." Nutrients 13, no. 3 (February 28, 2021): 799. http://dx.doi.org/10.3390/nu13030799.

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We aimed to report the implementation of a phenylketonuria (PKU) transition program and study the effects of follow-up with an adult team on metabolic control, adherence, and loss of follow-up. Fifty-five PKU patients were analysed in the study periods (SP): 2 years before (SP1) and after the beginning of adult care (SP2). Retrospective data on metabolic control and number of clinic appointments were collected for each SP, and protein intakes were analysed. In SP2, three patients (6%) were lost to follow-up. There was a small but statistically significant increase in median number of annual blood spots from SP1 to SP2: 11 (7–15) vs. 14 (7–20); p = 0.002. Mean ± SD of median blood Phe remained stable (525 ± 248 µmol/L vs. 552 ± 225 µmol/L; p = 0.100); median % of blood Phe < 480 µmol/L decreased (51 (4–96)% vs. 37 (5–85)%; p = 0.041) and median number of clinic appointments increased from SP1 to SP2: (5 (4–6) vs. 11 (8–13); p < 0.001). No significant differences were found regarding any parameter of protein intake. Our results suggest that the implementation of an adult service was successful as impact on metabolic control was limited and attendance remained high. Continuous dietetic care likely contributed to these results by keeping patients in follow-up and committed to treatment.
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Zang, Zhong-Lin, Sheng Zhao, Shuklachary Karnakanti, Cheng-Lin Liu, Pan-Lin Shao, and Yun He. "Catalytic Multisite-Selective Acetoxylation Reactions at sp2 vs sp3 C–H Bonds in Cyclic Olefins." Organic Letters 18, no. 19 (September 21, 2016): 5014–17. http://dx.doi.org/10.1021/acs.orglett.6b02458.

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21

Zucca, Antonio, Sergio Stoccoro, Maria Agostina Cinellu, Giovanni Minghetti, and Mario Manassero. "Cyclometallated derivatives of rhodium(III). Activation of C(sp3)–H vs. C(sp2)–H bonds." Journal of the Chemical Society, Dalton Transactions, no. 19 (1999): 3431–37. http://dx.doi.org/10.1039/a903614h.

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22

Paleti, Swathi, Zain A. Sobani, Thomas R. McCarty, Aditya Gutta, Anas Gremida, Raj Shah, Venkat Nutalapati, et al. "Impact of COVID-19 on gastroenterology fellowship training: a multicenter analysis of endoscopy volumes." Endoscopy International Open 09, no. 10 (September 16, 2021): E1572—E1578. http://dx.doi.org/10.1055/a-1526-1419.

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Abstract Background and study aims The COVID-19 pandemic has had a profound impact on gastroenterology training programs. We aimed to objectively evaluate procedural training volume and impact of COVID-19 on gastroenterology fellowship programs in the United States. Methods This was a retrospective, multicenter study. Procedure volume data on upper and lower endoscopies performed by gastroenterology fellows was abstracted directly from the electronic medical record. The study period was stratified into 2 time periods: Study Period 1, SP1 (03/15/2020 to 06/30/2020) and Study Period 2, SP2 (07/01/2020 to 12/15/2020). Procedure volumes during SP1 and SP2 were compared to Historic Period 1 (HP1) (03/15/2019 to 06/30/2019) and Historic Period 2 (HP2) (07/01/2019 to 12/15/2019) as historical reference. Results Data from 23 gastroenterology fellowship programs (total procedures = 127,958) with a median of 284 fellows (range 273–289; representing 17.8 % of all trainees in the United States) were collected. Compared to HP1, fellows performed 53.6 % less procedures in SP1 (total volume: 28,808 vs 13,378; mean 105.52 ± 71.94 vs 47.61 ± 41.43 per fellow; P < 0.0001). This reduction was significant across all three training years and for both lower and upper endoscopies (P < 0.0001). However, the reduction in volume was more pronounced for lower endoscopy compared to upper endoscopy [59.03 % (95 % CI: 58.2–59.86) vs 48.75 % (95 % CI: 47.96–49.54); P < 0.0001]. The procedure volume in SP2 returned to near baseline of HP2 (total volume: 42,497 vs 43,275; mean 147.05 ± 96.36 vs 150.78 ± 99.67; P = 0.65). Conclusions Although there was a significant reduction in fellows’ endoscopy volume in the initial stages of the pandemic, adaptive mechanisms have resulted in a return of procedure volume to near baseline without ongoing impact on endoscopy training.
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Hoȧi, Phạm Thị. "A Lonely Stroke That Slanted the Sky." Journal of Vietnamese Studies 16, no. 3 (2021): 122–28. http://dx.doi.org/10.1525/vs.2021.16.3.122.

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Schlaf, Marcel, Alan J. Lough, and Robert H. Morris. "Dihydrogen Thiolate vs Hydride Thiol: Reactivity of the Series of Complexes MH(CO)(L)(PPh3)2(M = Ru, Os; L = Pyridine-2-thiolate, Quinoline-8-thiolate) with Acid. X-ray Structure Determination of [Os(CO)(μ2-Spy)(SpyH)(PPh3)]2[BF4]2." Organometallics 15, no. 21 (January 1996): 4423–36. http://dx.doi.org/10.1021/om960411h.

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Grillot, Caroline. "Between Bitterness and Sweetness, When Bodies Say it All." Journal of Vietnamese Studies 7, no. 1 (January 1, 2012): 106–48. http://dx.doi.org/10.1525/vs.2012.7.1.106.

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As emblems of otherness in a space devoted to commercial and human exchanges and dedicated to mercantilism, Vietnamese women who cross the border and now live in areas bordering China have quickly come to represent their country—in the eyes of Chinese people—as a figure of marginal femininity. Observed, dated, used but rarely understood in a linguistic and cultural sense, it is their strong, sensual, and docile bodies that are primarily considered. Contradictory and accommodating images emerge and then expand in the discourses, portraying these women as submissive spouses, tireless workers, prostitutes, manipulators, heartless pragmatists, devoted companions, and ambiguous merchants. This articles explores how, between perception and experience, these women's availability, in every sense of the term, makes them both attractive and suspicious, and how their alliances with Chinese men crystallizes the social atmosphere of a border city like Hekou.
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Hong, Gang, Pradip D. Nahide, Uday Kumar Neelam, Peter Amadeo, Arjun Vijeta, John M. Curto, Charles E. Hendrick, Kelsey F. VanGelder, and Marisa C. Kozlowski. "Palladium-Catalyzed Chemoselective Activation of sp3 vs sp2 C–H Bonds: Oxidative Coupling To Form Quaternary Centers." ACS Catalysis 9, no. 4 (March 8, 2019): 3716–24. http://dx.doi.org/10.1021/acscatal.9b00091.

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Ye, Xiaohan, Zhengrong He, Tonia Ahmed, Keith Weise, Novruz G. Akhmedov, Jeffrey L. Petersen, and Xiaodong Shi. "1,2,3-Triazoles as versatile directing group for selective sp2 and sp3 C–H activation: cyclization vs substitution." Chemical Science 4, no. 9 (2013): 3712. http://dx.doi.org/10.1039/c3sc51211h.

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Pérez-Marín, Carlos Carmelo, Ander Arando, Francisco Maroto-Molina, Alberto Marín, and Juan Vicente Delgado. "Las subpoblaciones de espermatozoides y su calidad en fracciones producidas por la centrifugación de una sola capa en muestras frescas y normospérmicas de esperma de cordero." Revista Mexicana de Ciencias Pecuarias 12, no. 2 (September 15, 2021): 386–401. http://dx.doi.org/10.22319/rmcp.v12i2.5683.

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Single layer centrifugation (SLC) technique has been developed to select the best sperm population in the ejaculate in order to increase the fertilization rates by artificial insemination or in vitro fertilization. Normospermic ram semen samples containing 800 and 3,000 × 106 sperms/ml (C800 and C3000, respectively) were processed by SLC. Three sperm fractions were separated in each sample following silica-coloidal sperm centrifugation and sperm yield, quality and subpopulations were analyzed in each one. In C800 group, the sperm recovery rate did not vary in any studied fraction, but when samples were highly concentrated (C3000) the top fraction (F1) contained significantly higher spermatozoa than bottom fraction (F3). Also, it was observed that F1 in C3000 had got a significantly higher percentage of spermatozoa (53.2 %) than in C800, while the quantity of spermatozoa recovered in fraction 2 was lower (25.2 % vs 45.4 %). Based on the sperm motility parameters, three sperm subpopulations were identified: SP1, low velocity spermatozoa showing no progressive movement (19.1 %); SP2, rapid and progressive spermatozoa (43.7 %); and SP3, rapid spermatozoa but non-linear movement (37.2 %). While SLC has been implemented for sperm separation in suboptimal and/or low concentrated sperm samples, this trial demonstrates that SLC is not efficient to separate different sperm populations in normospermic ram sperm samples containing high concentrations of spermatozoa.
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Kocifaj, Miroslav. "Night sky luminance under clear sky conditions: Theory vs. experiment." Journal of Quantitative Spectroscopy and Radiative Transfer 139 (May 2014): 43–51. http://dx.doi.org/10.1016/j.jqsrt.2013.12.001.

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Catellani, Marta, Federica Cugini, and Domenico Tiefenthaler. "New pathways of site selective aromatic alkylation of palladium complexes: fragmentation to arenes vs. ring closure to hexahydromethano-fluorenes or -phenanthrenes." Canadian Journal of Chemistry 79, no. 5-6 (May 1, 2001): 742–51. http://dx.doi.org/10.1139/v01-047.

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Dimeric arylbicycloheptylpalladium halide complexes of type 1 undergo selective alkylation at the aromatic site by reaction with allyl, styryl, and benzyl bromides (RBr) via hexahydromethanopalladafluorenes (2). Ring closure of the resulting palladium complex (7) on sp2 and sp3 C-H bonds of a suitable R group then occurs with formation of hexahydromethanophenanthrene or hexahydromethanofluorene derivatives. Alternatively, substituted arenes derived from bicycloheptene deinsertion are formed. In some cases the latter can be obtained in substantial amounts when methyl isonicotinate is used as ligand.Key words: alkylations, C-H activation, palladium, palladacycles.
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Šandor, Ksenija, Svjetlana Terzić, Anja Vujnović, Eleonora Perak Junaković, Irena Žarković, and Miroslav Andrišić. "Razvoj SPE-HPLC-DAD metode za određivanje florfenikola i florfenikol amina u cerebrospinalnoj tekućini svinja." Veterinarska stanica 51, no. 2 (March 27, 2020): 129–38. http://dx.doi.org/10.46419/vs.51.2.3.

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A study of florfenicol (FF) and its metabo- lite florfenicol amine (FFA) in pig cerebrospinal fluid was conducted following repeated intramuscular administration of the original (reference) and a generic veterinary medicinal product (VMP) under the same experimental conditions (20 mg FF/kg body weight, 48-hour interval). Both VMPs are solutions for injection containing FF as an active substance in the concentration of 300 mg/mL and have been authorized in Croatia for use in cattle and pigs. In this study, clinically healthy pigs were randomly divided into three groups. The first group was treated with the reference VMP, the second with the generic VMP, while the third served as the control group. Animals were sacrificed at 216, 288 and 384 hours after the first drug administration. Cerebrospinal fluid samples were analysed by the optimized and validated high-performance liquid chromatography-diode array detector method (HPLC-DAD). The solid-phase extraction (SPE) technique was chosen for sample preparation. The HPLC-DAD method provides good linearity over the concentration range of 0.05 to 5.00 μg/mL for FF and FFA. Limits of detection were 0.0023 μg/mL for FF and 0.0100 μg/mL for FFA. Extraction recoveries of FF were from 86.6% to 111.8%, and of FFA from 91.7% to 98.8%. The SPE-HPLC-DAD method has been demonstrated to be a selective, sensitive and suitable analytical method for the determination of FF and FFA in cerebrospinal fluid. The present study was based on a preliminary study that quantified FF in pig plasma at 216 hours after the first application of reference or generic VMP. However, FF and FFA were not detected in any of the cerebrospinal fluid samples during the experimental period. According to the nature of biological fluids, the SPE-HPLC-DAD method can be suitable for further pharmacokinetic studies of FF in pig plasma and serum after intramuscular administration of VMPs.
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32

Slowe, Peter. "Private vs public." Science and Public Policy 18, no. 5 (October 1991): 327–28. http://dx.doi.org/10.1093/spp/18.5.327.

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33

Jassi, H. K., A. Jain, Sarika Arora, and R. Chitra. "Effect of soy proteins Vs soy isoflavones on lipid profile in postmenopausal women." Indian Journal of Clinical Biochemistry 25, no. 2 (April 2010): 201–7. http://dx.doi.org/10.1007/s12291-010-0036-8.

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Koljević, Bogdana. "ETIKA SLOBODE VS. ETIKA LIBERALISTIČKOG PRAGMATIZMA." Srpska politička misao 52, no. 2 (2016): 27–42. http://dx.doi.org/10.22182/spm.5222016.2.

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Reinwald, Susan, and Connie M. Weaver. "Soy Components vs. Whole Soy: Are We Betting Our Bones on a Long Shot?" Journal of Nutrition 140, no. 12 (December 1, 2010): 2312S—2317S. http://dx.doi.org/10.3945/jn.110.124008.

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36

Pérez-Temprano, Mónica H., Joy M. Racowski, Jeff W. Kampf, and Melanie S. Sanford. "Competition between sp3-C–N vs sp3-C–F Reductive Elimination from PdIV Complexes." Journal of the American Chemical Society 136, no. 11 (February 28, 2014): 4097–100. http://dx.doi.org/10.1021/ja411433f.

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37

Musgrove, Mary, Rachel M. Kenney, Ronald Kendall, Robert Tibbetts, Linoj Samuel, Mike Peters, and Susan Davis. "Communicating Microbiology Results. It’s Not Just What You Say, But How You Say It." Open Forum Infectious Diseases 4, suppl_1 (2017): S28. http://dx.doi.org/10.1093/ofid/ofx162.069.

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Abstract Background Gaps in microbiology communication can lead to suboptimal antibiotic prescribing. In May 2016, our laboratory modified reporting of respiratory cultures growing commensal flora only to specify “no methicillin-resistant Staphylococcus aureus/MRSA or Pseudomonas aeruginosa” (PA). The purpose of this study was to compare MRSA and PA antibiotic therapy utilization before and after the change. Methods IRB approved, quasi-experiment at four hospitals with an antimicrobial stewardship program. Dates: August 1, 2015–January 31, 2016 and August 1, 2016–January 31, 2017. Included: ≥18 years, commensal flora only respiratory culture, empiric MRSA and PA antibiotic for treatment of lower respiratory infection. Excluded: non-respiratory infection. Primary outcome: MRSA or PA therapy de-escalated. Secondary outcomes: time to culture result, MRSA and PA antibiotic days of therapy, length of stay. Safety outcomes: acute kidney injury (AKI), C. difficile (CDI), subsequent multi-drug-resistant organism (MDRO), in-hospital all-cause mortality. Results Two hundred and ten patients included, 105 per group. Median age 64 and 61 years, male sex 52% and 56% in pre- and post-group, respectively. Empiric antibiotics, pre vs. post: vancomycin 94% vs. 95%; cefepime 66% vs. 36%; piperacillin–tazobactam 10% vs. 46%. MRSA or PA antibiotics de-escalated: 39% pre and 73% post (P &lt; 0.001). See Table 1 for variables associated with antibiotic de-escalation. Days of therapy: 7 vs. 5 days (P &lt; 0.001). AKI 31% vs. 14% (P = 0.003). Eight subsequent MDRO in pre and one in post (P = 0.035). No differences: time to culture result, length of stay, mortality, CDI. Conclusion Improved microbiology communication to assist prescriber interpretation of commensal respiratory flora was associated with a reduction in the proportion of patients that received antibiotics targeting MRSA and PA. Disclosures S. Davis, Merck: Received grant through college that I’m faculty for, Grant recipient; Allergan: Speaker’s Bureau, Consulting fee; Allergan: Consultant and Scientific Advisor, Consulting fee; Medicines Company: Consultant and Scientific Advisor, Consulting fee; Zavante: Consultant and Scientific Advisor, Consulting fee.
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Ljuma Skupnjak, Lana, Anto Vrdoljak, and Nikol Očuršćak. "Duration of immunity acquired by vaccination with the live attenuated vaccine Avishield IB H120 against infectious bronchitis virus in SPF chickens." Veterinarska stanica 51, no. 6 (July 1, 2020): 621–26. http://dx.doi.org/10.46419/vs.51.6.7.

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The most effective means of controlling infectious bronchitis in poultry is by vaccination. Live attenuated vaccines based on the H120 strain (Mass serotype) are the most commonly used vaccines. Since vaccination is often performed in the hatchery, long duration of immunity is preferred. Avishield IB H120, a live attenuated vaccine based on the strain H120 is registered across the European Union and other countries, and has a declared immunity period of up to 5 weeks after vaccination. This study presents the results of an additional survey demonstrating protection against challenge with the IBV strain M41 up to 8 weeks after a single vaccination with Avishield IB H120. Seven weeks after vaccination, 94% of chickens vaccinated by spray were protected against the challenge. Eight weeks after vaccination, 80% of spray vaccinated chickens and 75% of orally vaccinated chickens were still protected against the challenge with virulent IBV.
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Maldonado, Pedro Antonio, Kyle P. Norris, Maria E. Florian-Rodriguez, Nemi M. Shah, and Clifford Y. Wai. "Sacrocolpopexy With Concomitant Total vs Supracervical Hysterectomy." Female Pelvic Medicine & Reconstructive Surgery 25, no. 3 (2019): 213–17. http://dx.doi.org/10.1097/spv.0000000000000532.

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40

Bengtson, Neal M. "Microcomputer vs. mainframe simulations: A case study." Software: Practice and Experience 19, no. 10 (October 1989): 957–65. http://dx.doi.org/10.1002/spe.4380191004.

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41

Okoroafor, Rita, Carlos Chalbaud, Anton Andreev, Siddartha Gupta, J. Shaun Toralde, and Josh Etkind. "Technical vs. Managerial Careers: What Experienced Professionals Say." Way Ahead 05, no. 02 (June 1, 2009): 5–9. http://dx.doi.org/10.2118/0209-005-twa.

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42

Paykari, P., S. Pires, J. L. Starck, and A. H. Jaffe. "Sparsely sampling the sky: Regular vs. random sampling." Astronomy & Astrophysics 581 (September 2015): A113. http://dx.doi.org/10.1051/0004-6361/201526236.

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43

Stoccoro, Sergio, Barbara Soro, Giovanni Minghetti, Antonio Zucca, and Maria A. Cinellu. "Reactivity of 6-(2-tolyl)- and 6-(2,6-xylyl)-2,2′-bipyridines with palladium(II) derivatives. Selective C(sp3)H vs. C(sp2)H activation." Journal of Organometallic Chemistry 679, no. 1 (August 2003): 1–9. http://dx.doi.org/10.1016/s0022-328x(03)00457-1.

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44

Stelmach, Paweł. "SPA SERVICES DISTRIBUTION STRUCTURE VS. SPA RESORT SPECIALIZATION. THE FRAMEWORK OF RESEARCH AND PARTIAL FINDINGS." Prace Naukowe Uniwersytetu Ekonomicznego we Wrocławiu, no. 473 (2017): 552–61. http://dx.doi.org/10.15611/pn.2017.473.51.

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45

Cabezas-Camarero, Santiago, Vanesa García-Barberán, Rebeca Pérez-Alfayate, María L. Gandía, Isabel Díaz-Millán, and Pedro Pérez-Segura. "Plasma PD-L1 levels according to histologic grade and IDH status in patients with gliomas." Journal of Clinical Oncology 38, no. 5_suppl (February 10, 2020): 69. http://dx.doi.org/10.1200/jco.2020.38.5_suppl.69.

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69 Background: Plasma immune biomarkers such as soluble plasma PD-L1 (sPD-L1) may serve as surrogates of the immune condition of cancer patients and be potential markers of response to different immunotherapy modalities. Very few data exist regarding sPD-L1 in patients with primary brain tumors. Our aim was to study the levels of sPD-L1 in patients with gliomas according to histologic grade and IDH mutation status. Methods: Patients (pts) with grade II to IV gliomas were prospectively enrolled. Single-time-point plasma samples were obtained prior to adjuvant radiotherapy +/- chemotherapy. sPD-L1 determined using ELISA with a rabbit polyclonal anti-PDL1/CD274 antibody as capture reagent. Results: Between February 2017 and August 2019, 44 patients (pts) with gliomas and 12 healthy controls (HC) were enrolled. N=11 grade II, n=9 grade III, n=24 grade IV; n=26 IDHwt, n=18 IDHmut. Higher sPD-L1 levels in glioma pts compared to HC (60.8 vs 47.8 ng/ml, p=0.05). Higher sPD-L1 levels in grade II vs grades III-IV (73.3 vs 60 ng/ml, p=0.09). Higher sPD-L1 in IDHmut grades II-III vs IDHwt grades II-III + IDHmut/wt grade IV (73 vs 59 ng/ml, p=0.07). Non-significantly higher sPD-L1 in grades II-III vs grade IV (73 vs 59 ng/ml, p=0.46). No difference in sPD-L1 in IDHmut vs IDHwt (63.3 vs 59.1 ng/ml, p=0.496), nor in IDHwt vs HC (59.1 vs 47.8 ng/ml, p=0.109). Trend to significance in IDHmut vs HC (63.3 vs 47.8, p=0.062). Conclusions: sPD-L1 levels were significantly higher in glioma pts compared to HC. A trend was seen towards higher sPD-L1 levels in lower-grade (grades II, III) IDHmut gliomas. These findings may indicate a different systemic immune profile for currently defined glioma groups based on histologic grade and IDH status and merit confirmation in a larger sample.
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Chatupheeraphat, Adisak, Hsuan-Hung Liao, Watchara Srimontree, Lin Guo, Yury Minenkov, Albert Poater, Luigi Cavallo, and Magnus Rueping. "Ligand-Controlled Chemoselective C(acyl)–O Bond vs C(aryl)–C Bond Activation of Aromatic Esters in Nickel Catalyzed C(sp2)–C(sp3) Cross-Couplings." Journal of the American Chemical Society 140, no. 10 (February 20, 2018): 3724–35. http://dx.doi.org/10.1021/jacs.7b12865.

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Mabssout, M., and M. I. Herreros. "Runge–Kutta vs Taylor-SPH: Two time integration schemes for SPH with application to Soil Dynamics." Applied Mathematical Modelling 37, no. 5 (March 2013): 3541–63. http://dx.doi.org/10.1016/j.apm.2012.08.014.

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48

Patnam, Radhika, Autumn L. Edenfield, and Steven E. Swift. "Standing Vs Supine; Does it Matter in Cough Stress Testing?" Female Pelvic Medicine & Reconstructive Surgery 23, no. 5 (2017): 315–17. http://dx.doi.org/10.1097/spv.0000000000000377.

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Jang, Yoon Jae. "The influence of mobile phone use for entertainment vs. convenience vs. information-seeking on academic adjustment: The mediating effect of concentration and peer relationships." Studies on Korean Youth 31, no. 2 (May 31, 2020): 321–42. http://dx.doi.org/10.14816/sky.2020.31.2.321.

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June-Hee Na, Yim Dong Wook, 김양수, and 최기하. "Experiential Value of Suanbo Spa Zone: Expectation vs. Performance." Journal of Product Research 35, no. 1 (February 2017): 51–57. http://dx.doi.org/10.36345/kacst.2017.35.1.005.

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