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Journal articles on the topic 'Spy Vs. Spy'

Author: Grafiati

Published: 4 June 2021

Last updated: 28 July 2025

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1

Fanti, Giulia, Peter Kairouz, Sewoong Oh, and Pramod Viswanath. "Spy vs. Spy." ACM SIGMETRICS Performance Evaluation Review 43, no. 1 (2015): 271–84. http://dx.doi.org/10.1145/2796314.2745866.

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2

Waldner, Liz. "Spy vs. Spy, and: Let There Be Light." Colorado Review 37, no. 1 (2010): 141–42. http://dx.doi.org/10.1353/col.2010.0083.

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3

Scott, Cord A. "Cold War politics, Cuba, and Spy vs. Spy." Journal of Graphic Novels and Comics 11, no. 3 (2019): 315–24. http://dx.doi.org/10.1080/21504857.2019.1582545.

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4

Ng, K. W. "Spy vs. Spy: Recruiting Stem Cells to the War on Cancer." Science Translational Medicine 2, no. 47 (2010): 47ec137. http://dx.doi.org/10.1126/scitranslmed.3001625.

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5

de Castro, Guilherme Vieira, and Alessio Ciulli. "Spy vs. spy: selecting the best reporter for 19F NMR competition experiments." Chemical Communications 55, no. 10 (2019): 1482–85. http://dx.doi.org/10.1039/c8cc09790a.

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6

Norets, Maksim, Vitaliy Lubeyev, and Svetlana Lubeyeva. "The English spy novels of the “cold war” period and the concept “we” vs “they” as their basis." SHS Web of Conferences 69 (2019): 00084. http://dx.doi.org/10.1051/shsconf/20196900084.

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This investigation is dedicated to the analysis of the works of the British authors of the spy novels of the “Cold War” period, who have formed a spy novel as the separate genre. In the work the investigator takes the attempt to analyse the concept “we” vs “they” as the basic structure of the plot forming in the context of historical events taking into account the belonging of the author to the secret service. The attention of the author of the investigation is focused on the new forms of realization of the plot line and the modification of the protagonist and antagonist.

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7

Vidula, Neelima, Christina Yau, and Hope S. Rugo. "Trop2 gene expression (Trop2e) in primary breast cancer (BC): Correlations with clinical and tumor characteristics." Journal of Clinical Oncology 35, no. 15_suppl (2017): 1075. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.1075.

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1075 Background: Trophoblast antigen 2 (Trop2) is a glycoprotein expressed by many cancers. A phase I study of the trop2 antibody drug conjugate (ADC) IMMU-132 has shown promising activity in triple negative (TN) BC. We studied associations of primary BC trop2e with clinical characteristics, outcomes, and selected genes in publically available databases. Methods: Trop2e was evaluated with microarray data from the neoadjuvant I-SPY 1 (n=149), METABRIC (n=1992) & TCGA (n=817) databases. Associations with clinical features were assessed with the Kruskal-Wallis test (all). Correlations with ch

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8

CARABAS, TEODORA. "Tales Calculated to Drive You MAD": The Debunking of Spies, Superheroes, and Cold War Rhetoric in Mad Magazine's "SPY vs SPY"." Journal of Popular Culture 40, no. 1 (2007): 4–24. http://dx.doi.org/10.1111/j.1540-5931.2007.00351.x.

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9

Ростиславлева, Н. В. "Protestant activities during the First World War: spy fever vs Christian piety." Диалог со временем, no. 86(86) (April 3, 2024): 266–73. http://dx.doi.org/10.21267/aquilo.2024.86.86.017.

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В статье рассматриваются особенности отношения властных структур к представителям неправославных христианских конфессий в годы Первой мировой войны. На территории Российской империи к началу XX в. проживало около 2 млн. этнических немцев, как подданных Германской, так и Российской империй. Обычно они сохраняли верность своей конфессии. Немецкое население, прежде всего мужчины от 17 до 45 лет, в условиях мирового конфликта активно подвергалось депортациям и интернированию. Лютеранские пасторы, их жены, паства Москвы, Риги, Ревеля, оказывали материальную и духовную поддержку как высланному немец

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10

Lethier, Pierre, and Clara Laurent. "Marthe Richard vs. Mata Hari: The (De)mythologizing of a French Spy." Studies in French Cinema 9, no. 1 (2009): 63–73. http://dx.doi.org/10.1386/sfc.9.1.63_1.

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11

Hindersmann, Jost. "Nordic noir vs. spies in the cold: The reception of Scandinavian TV and film adaptations in Germany." Journal of Scandinavian Cinema 9, no. 3 (2019): 277–87. http://dx.doi.org/10.1386/jsca_00004_1.

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Scandinavian crime novels and their adaptations as TV dramas and films, commonly known as Nordic noir, are very popular in Germany. Nordic noir often has a political content and when spies appear, they are usually portrayed negatively. Scandinavian spy novels and their adaptations, on the other hand – with the exception of Guillou’s Coq Rouge series – never reached wide audiences in Germany.

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12

Gol Man Gurung. "State Vs Individual in Christopher Greyson's And Then She Was Gone." Interdisciplinary Journal of Management and Social Sciences 3, no. 1 (2022): 64–68. http://dx.doi.org/10.3126/ijmss.v3i1.50233.

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The research examines state's subjugation of individual power and authority in Christopher Greyson's And Then She Was Gone. It introduces power theory and shows state's exercise of power and use of force against individual power. The state power defines law and authority which is mandatory and individual power exercise is punishable. As novel identifies a character who is professional spy however, he cannot define truth and justice which is state's perspective. Truth is no matter for state but it defines truth. The character fights for justice and truth but the state never accepts the justice

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13

Basu, Amrita, Saumya Umashankar, Denise M. Wolf, et al. "Early adverse symptoms to predict response to treatment among patients in the I-SPY trial." Journal of Clinical Oncology 43, no. 16_suppl (2025): 610. https://doi.org/10.1200/jco.2025.43.16_suppl.610.

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610 Background: The adverse event (AE) landscape in oncology is changing due to the introduction of immunotherapy and antibody drug conjugates. These AEs come with both short and long-term symptoms that significantly impact patient quality of life. Monitoring for early onset of symptoms could optimize therapy for a particular patient, maximizing potential efficacy while mitigating toxicity. It is also possible that some toxicities are directly associated with drug sensitivity. We sought to identify symptoms associated with pathologic complete response (pCR) using patient-reported outcomes (PRO

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14

Lin, C., D. Moore, A. DeMichele, et al. "Detection of locally advanced breast cancer in the I-SPY TRIAL (CALGB 150007/150012, ACRIN 6657) in the interval between routine screening." Journal of Clinical Oncology 27, no. 15_suppl (2009): 1503. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.1503.

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1503 Background: It is assumed that most locally advanced breast cancers (LABC) could be detected at an earlier stage with routine screening. However, LABCs may present between screens as interval cancers (IC). ICs present at an earlier age, with higher grade, larger size, and are associated with lower survival, compared to screen-detected cancers (SDC), and comprise 17% of cancers from population-based screening programs. We evaluated the screening history in patients with LABCs from the I SPY TRIAL, to determine the frequency of screening and ICs. Methods: Of 221 pts enrolled in the I-SPY TR

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Basu, Amrita, Saumya Umashankar, Michelle Melisko, et al. "Abstract GS5-04: Identification of symptoms that are associated with irAEs in the I-SPY clinical trial." Cancer Research 83, no. 5_Supplement (2023): GS5–04—GS5–04. http://dx.doi.org/10.1158/1538-7445.sabcs22-gs5-04.

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Abstract Background. Immunotherapy has emerged as an important component of neoadjuvant therapy for some patients with breast cancer (BC). As a result, immune-related adverse events (irAEs) are increasing and have effects on both short and long term symptoms significantly impacting patient quality of life. BC patients may develop new conditions including arthralgias, gastrointestinal issues, endocrinopathies, and fatigue during or after cancer therapy that may be acute or long-lasting in nature. Monitoring for early onset and severity of symptoms, and adjusting treatment and symptom management

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16

Devgan, Yuvraj, Sabaretnam Mayilvaganan, Anjali Mishra, Gyan Chand, Gaurav Agarwal, and Amit Agarwal. "Comparison of indocyanine green angiography vs intraoperative parathyroid hormone in early prediction of risk of post-thyroidectomy hypocalcemia: a prospective cohort study." Annals of Medicine & Surgery 86, no. 2 (2024): 678–88. http://dx.doi.org/10.1097/ms9.0000000000001578.

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Introduction: Indocyanine green (ICG) angiography is the ‘real-time intraoperative imaging’ technique used to reduce the chances of hypoparathyroidism in post-thyroidectomy patients. In our study, the authors predicted the risk of early post-thyroidectomy hypocalcemia by intraoperative evaluation of parathyroid gland perfusion by ICG angiography. Materials and methods: In patients who underwent total thyroidectomy, ICG angiography was done using the SPY PHI imaging system (Stryker). Post-thyroid specimen removal, scoring of parathyroids was done in spy contrast mode. All 4 or <4 visualized

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17

DeMichele, A., L. Dunn, P. Gimotty, et al. "Loss of p27 expression and response to neoadjuvant chemotherapy: Results from the I-SPY Trial (CALGB150007/150012, ACRIN6657)." Journal of Clinical Oncology 27, no. 15_suppl (2009): 11091. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.11091.

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11091 Background: Loss of expression of the cyclin-dependent kinase (cdk) inhibitor p27 has been associated with decreased survival among patients receiving adjuvant chemotherapy. The I-SPY Trial is a multicenter study of locally advanced breast cancer in which pretreatment tumor biopsies were obtained prior to the administration of anthracycline and taxane-based neoadjuvant therapy, and serial MRIs were performed to assess response to treatment. The aim of this study was to determine if loss of tumor p27 expression was associated with response to cytotoxic therapy. Methods: Eligible patients

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18

EDGAR, WILLIAM. "Eric Metaxas. Bonhoeffer: Pastor, Martyr, Prophet, Spy: A Righteous Gentile vs. the Third Reich. Nashville: Nelson, 2010." Unio Cum Christo 1, no. 1 (2015): 127. http://dx.doi.org/10.35285/ucc1.1-2.2015.rev6.

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19

Thomas, Alexandra, Amy Sanders Clark, Christina Yau, et al. "Molecular subtype to predict pathologic complete response in HER2-positive breast cancer in the I-SPY2 trial." Journal of Clinical Oncology 40, no. 16_suppl (2022): 510. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.510.

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510 Background: HER2-positive breast cancer (bc) is a very heterogenous disease. We hypothesized that molecular subtype may predict disease response to investigational agents in HER2+ bc. Here, we report the pathologic complete response (pCR) rate in the first six agents tested in HER2+ bc in the I-SPY 2 trial for the full HER2+ cohort, by molecular subtype, and by disease receptor status. Methods: Women with HER2+ tumors which were > 2.5 cm were eligible. The I-SPY2 platform trial tests novel agents given neoadjuvantly with a backbone of taxol (T) and trastuzumab (H) followed by doxorubici

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20

Li, Jiali, Christina Yau, Michael Campbell, Laura Esserman, John W. Park, and Hope S. Rugo. "Correlation of receptor activator of nuclear factor kappa b (RANK) expression in breast cancer (BC) at the time of diagnosis with recurrence-free survival (RFS) and risk of bone-dominant metastases (BDM) in the I-SPY 1 trial (CALGB 150007/150012; ACRIN 6657)." Journal of Clinical Oncology 30, no. 27_suppl (2012): 2. http://dx.doi.org/10.1200/jco.2012.30.27_suppl.2.

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2 Background: RANK is a tumor necrosis factor receptor family protein that is critical to bone turnover. The ligand to RANK (RANKL) can induce metastases from RANK-expressing tumor cells, and treatment with a RANKL inhibitor can reduce BC metastases (mets) in pre-clinical models and there is an FDA approved drug that targets RANKL. Osteoprotegerin (OPG) is a RANKL decoy receptor that blocks the interaction of RANK/RANKL. I-SPY 1 was a multicenter neoadjuvant trial with well annotated gene expression data and detailed clinical outcomes; we studied the impact of RANK expression on both RFS and B

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21

Isaacs, Claudine, Rita Nanda, Jo Chien, et al. "Abstract GS5-03: Evaluation of anti-PD-1 Cemiplimab plus anti-LAG-3 REGN3767 in early-stage, high-risk HER2-negative breast cancer: Results from the neoadjuvant I-SPY 2 TRIAL." Cancer Research 83, no. 5_Supplement (2023): GS5–03—GS5–03. http://dx.doi.org/10.1158/1538-7445.sabcs22-gs5-03.

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Abstract Background: I-SPY2 is a multicenter, phase 2 trial using response-adaptive randomization within biomarker subtypes defined by hormone-receptor (HR), HER2, and MammaPrint (MP) status to evaluate novel agents as neoadjuvant therapy for high-risk breast cancer. The primary endpoint is pathologic complete response (pCR). Cemiplimab is an anti-PD-1 inhibitor approved for the treatment of NSCLC and cutaneous basal and squamous cell CA. Lymphocyte activation gene 3 (LAG-3) binds MHC class II leading to inhibition of T-cell proliferation and activation and is often co-expressed with PD-1. REG

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Kyalwazi, Beverly, Christina Yau, Olufunmilayo Olopade, et al. "Abstract GS4-02: Analysis of clinical outcomes and expression-based immune signatures by race in the I-SPY 2 trial." Cancer Research 82, no. 4_Supplement (2022): GS4–02—GS4–02. http://dx.doi.org/10.1158/1538-7445.sabcs21-gs4-02.

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Abstract Background Transcriptomic immune-related gene signatures have been associated with achievement of pathologic complete response (pCR) and prognosis in the neoadjuvant setting. I-SPY 2 is a multicenter, phase 2 platform trial using response-adaptive randomization within subtypes defined by receptor status (HR/HER2) and MammaPrint (MP) risk to evaluate novel agents as neoadjuvant therapy for women with high-risk breast cancer. Given racial disparities in mortality from breast cancer and the paucity of racial demographic data from clinical trials, we aimed to evaluate the association betw

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Basu, Amrita, Saumya Umashankar, Denise M. Wolf, et al. "Identifying symptom clusters associated with acute and chronic fatigue in patients with breast cancer treated with neoadjuvant therapy on the I-SPY 2 trial." JCO Oncology Practice 20, no. 10_suppl (2024): 271. http://dx.doi.org/10.1200/op.2024.20.10_suppl.271.

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271 Background: Many studies have shown that fatigue is associated with poor outcomes such as quality of life and physical function in breast cancer survivors.Early treatment of symptoms that result in persistent fatigue may be a strategy to mitigate long-term fatigue.As a result, we studied symptoms and developed risk estimates for patients that are most likely to develop fatigue by pre-surgery and follow up among patients treated on the I-SPY 2 neoadjuvant trial. I-SPY 2 is a phase-II adaptive trial for high-risk early-stage breast cancer patients. Methods: In this retrospective cohort study

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Stringer-Reasor, Erica, Rebecca A. Shatsky, Jo Chien, et al. "Abstract PD11-01: PD11-01 Evaluation of the PD-1 Inhibitor Cemiplimab in early-stage, high-risk HER2-negative breast cancer: Results from the neoadjuvant I-SPY 2 TRIAL." Cancer Research 83, no. 5_Supplement (2023): PD11–01—PD11–01. http://dx.doi.org/10.1158/1538-7445.sabcs22-pd11-01.

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Abstract Background: I-SPY2 is a multicenter, phase 2 trial using response-adaptive randomization within biomarker subtypes defined by hormone-receptor (HR), HER2, and MammaPrint (MP) status to evaluate novel agents as neoadjuvant therapy for high-risk breast cancer. The primary endpoint is pathologic complete response (pCR). Cemiplimab (Cemi) is a PD-1 inhibitor approved for the treatment of NSCLC, cutaneous basal, and squamous cell cancer. Here, we report current efficacy rates of Cemi in combination with paclitaxel followed by AC. Methods: Women with tumors ≥ 2.5cm were eligible for screeni

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Ahmed, Fahad Shabbir. "Use of machine learning to predict pathological complete response using multi-modal data from I-SPY2 clinical trials." Journal of Clinical Oncology 41, no. 16_suppl (2023): 592. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.592.

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592 Background: The objective of the current analysis of the I-SPY 2 data from multiple breast cancer clinical trials for stages II and III cancers was to look at the possibility of developing a machine learning algorithm to predict pathological complete response using multimodal data. Methods: Imagining, clinical and biomarkers data form the I-SPY 2 trial was used in this analysis. Four different experiments were designed for to assess different data pre-processing and machine learning methods mainly deep neural networks (DNN) and random forest (RF) classifiers. Experiment 1 and 3 use DNNs wh

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Potter, David A., Erin Roesch, Christina Yau, et al. "Abstract PD8-07: Evaluation of Tucatinib + (Paclitaxel + Pertuzumab + Trastuzumab) followed by AC in high-risk HER2 positive (HER2+) stage II/III breast cancer: Results from the I-SPY 2 TRIAL." Cancer Research 82, no. 4_Supplement (2022): PD8–07—PD8–07. http://dx.doi.org/10.1158/1538-7445.sabcs21-pd8-07.

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Abstract Background: I-SPY 2 is a multicenter, phase 2 trial using response-adaptive randomization within molecular subtypes defined by receptor status and MammaPrint (MP) risk to evaluate novel agents as neoadjuvant therapy for women with high-risk breast cancer. Tucatinib is a potent HER2 (ErbB2) tyrosine kinase inhibitor, selective for HER2 vs. epidermal growth factor receptor (EGFR) and is active vs. brain metastases. Safety and efficacy of tucatinib combined with paclitaxel, pertuzumab, and trastuzumab are unknown and were tested in a planned 10 patient (pt) safety run-in of the I-SPY 2 t

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Magbanua, Mark Jesus M., Hope Rugo, Lamorna A. Brown Swigart, et al. "Abstract P5-05-05: Monitoring for response and recurrence in neoadjuvant-treated hormone receptor-positive HER2-negative breast cancer by personalized circulating tumor DNA testing." Cancer Research 83, no. 5_Supplement (2023): P5–05–05—P5–05–05. http://dx.doi.org/10.1158/1538-7445.sabcs22-p5-05-05.

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Abstract Background: The detection of circulating tumor DNA (ctDNA) may serve as an early predictor of response and recurrence. In this study, we used a tumor-informed ctDNA test to monitor clinical outcomes in patients with high-risk hormone receptor-positive HER2-negative (HR+HER2-) tumors who received neoadjuvant chemotherapy (NAC) on the I-SPY 2 trial (NCT01042379). Methods: We collected blood samples at pretreatment, during (at 3 and 12 weeks after initiation of paclitaxel-based treatment with or without an investigational drug), after NAC prior to surgery, 4 weeks after surgery, and annu

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Zimmermann, Judith, Julia Carmona-Bozo, Nu N. Le, et al. "Abstract P6-01-33: Diffusion-weighted magnetic resonance imaging for subtype-specific prediction of pathologic complete response in neoadjuvant chemotherapy." Cancer Research 83, no. 5_Supplement (2023): P6–01–33—P6–01–33. http://dx.doi.org/10.1158/1538-7445.sabcs22-p6-01-33.

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Abstract Background: The apparent diffusion coefficient (ADC) presents a biomarker that is sensitive to tumor cellularity. ADC maps can be calculated from non-contrast diffusion-weighted magnetic resonance imaging (DW-MRI) measurements. ACRIN 6698, a sub-study of clinical trial I-SPY 2, investigated mean ADC – averaged over the whole tumor – as a marker to predict pathologic complete response (pCR) [1]. This work compares a group of histogram-based ADC metrics in addition to mean ADC for early prediction of pCR in patients stratified by breast cancer subtype. Methods: We performed a retrospect

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Kang, Jamie, and Tim Leung. "Asynchronous ADRs: overnight vs intraday returns and trading strategies." Studies in Economics and Finance 34, no. 4 (2017): 580–96. http://dx.doi.org/10.1108/sef-10-2016-0254.

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Purpose The purpose of this study is to analyze the overnight and intraday returns of the most traded American Depositary Receipts (ADRs) of Asian companies, understand the different levels of volatilities realized in these asynchronous markets and develop trading strategies based on empirical findings. Design/methodology/approach This study presents an empirical analysis on the overnight and intraday returns of Asian ADRs. The authors propose a measure to quantify the relative contributions of the intraday and overnight returns to the ADR's total volatility. Furthermore, the return difference

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Jung, Byung Joon. "Lyom Dongjin, Spy of Kwantung Army Kempeitai vs. Kim Hyuk, Independence Fighter: Cross Rancor of Alumni of Luoyang Military Academy and Origins of the White Shirts Society." Critical Review of History 135 (May 31, 2021): 289–331. http://dx.doi.org/10.38080/crh.2021.05.135.289.

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Meisel, Jane Lowe, Katia Khoury, Amy Jo Chien, et al. "Rates of pathologic complete response (pCR)after neoadjuvant datopotamab deruxtecan (Dato): Results from the I-SPY2.2 trial." Journal of Clinical Oncology 42, no. 17_suppl (2024): LBA509. http://dx.doi.org/10.1200/jco.2024.42.17_suppl.lba509.

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LBA509 Background: I-SPY2.2 is a multicenter phase 2 platform sequential multiple assignment randomized trial (SMART) evaluating novel experimental regimens in the neoadjuvant breast cancer setting. The novel therapy is given as first in a sequence (Block A), followed by standard chemo/targeted therapies (Block B/C) if indicated. The goal is to identify agents that lead to pCR after novel targeted agents alone, or in sequence with optimal therapy assigned based on the tumor response predictive subtype (RPS). RPS incorporates expression-based immune, DNA repair deficiency (DRD), and luminal sig

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Ryu, Min-Hee, Eishi Baba, Kyung Hee Lee, et al. "Phase III trial of a 3-weekly versus 5-weekly schedule of S-1 plus cisplatin (SP) combination chemotherapy for first-line treatment of advanced gastric cancer (AGC): SOS study." Journal of Clinical Oncology 31, no. 18_suppl (2013): LBA4024. http://dx.doi.org/10.1200/jco.2013.31.18_suppl.lba4024.

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LBA4024 Background: 5-weekly S-1 plus cisplatin (SP5: S-1 80-120 mg/body/day on D1-21, cisplatin 60 mg/m2 on D8, every 5 weeks) has become a standard first-line chemotherapy for AGC in Japan based on the SPIRITS trial (Lancet Oncol. 2008;9:215). To strengthen the low-dose intensity of cisplatin in this SP5 for greater efficacy, a 3-weekly S-1 plus cisplatin (SP3: S-1 80 mg/m2/day on D1-14, cisplatin 60 mg/m2on D1, every 3 weeks) has been developed in Korea (Cancer Chemother Pharmacol. 2008;61:837). Methods: This SOS study was a multicenter, randomized, open-label, phase III study to evaluate w

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You, Yipeng, Ming Yu Jin, Guanyu Tao, and Xiangyou Xing. "Highly Efficient Kinetic Resolution of Aryl-Alkenyl Alcohols by Ru-Catalyzed Hydrogen Transfer." Molecules 26, no. 24 (2021): 7475. http://dx.doi.org/10.3390/molecules26247475.

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No matter through asymmetric reduction of ketones or kinetic resolution of secondary alcohols, enantioselective synthesis of the corresponding secondary alcohols is challenging when the two groups attached to the prochiral or chiral centers are spatially or electronically similar. For examples, dialkyl (sp3 vs. sp3), diaryl (sp2 vs. sp2), and aryl-alkenyl (sp2 vs. sp2) alcohols are difficult to produce with high enantioselectivities. By exploiting our recently developed Ru-catalysts of minimal stereogenicity, we reported herein a highly efficient kinetic resolution of aryl-alkenyl alcohols thr

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Hassan, Iyad, Lina Hassan, Mohamad Askar, and Rawan Khalid Salih. "Optimizing Parathyroid Preservation in Thyroidectomy: The Burjeel Protocol Utilizing Intraoperative Indocyanine Green Near-Infrared Fluorescence Imaging." Biomedicines 13, no. 5 (2025): 1044. https://doi.org/10.3390/biomedicines13051044.

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Background: Autofluorescence can identify parathyroid glands and protect their vasculature during thyroid surgery to prevent postoperative hypoparathyroidism. This study evaluates the Burjeel intraoperative protocol using near-infrared indocyanine green (ICG-NiR) imaging to preserve parathyroid glands during total thyroidectomy. Methods: This study conducted a single-centre retrospective matched cohort analysis involving 156 consecutive patients who underwent thyroidectomy using the Burjeel ICG-guided near-infrared (NiR) fluorescence protocol (“ICG group”). Patients were matched 1:1 based on g

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Talbott, P., and J. Shilpa. "Precision Pathology: Unveiling the role of Interval Sectioning Protocol for Optimal Diagnosis in Pancreatic, Ampullary, and Bile Duct Biopsies." American Journal of Clinical Pathology 162, Supplement_1 (2024): S104. http://dx.doi.org/10.1093/ajcp/aqae129.231.

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Abstract Introduction/Objective Endoscopic techniques offer advanced diagnostics but encounter challenges in obtaining limited pancreaticobiliary biopsies, including ampullary (AMP), EUS-guided pancreatic (PAN), and spy bite biliary (BD) biopsies. Interval sectioning optimizes immunohistochemical stain utility and tissue conservation. This study evaluates interval sectioning protocols’ impact on diagnostic precision and tissue preservation at our institution. Methods/Case Report This analysis examines cases over four months before and after a protocol change, focusing on AMP, BD, and PAN biops

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Peres, Maria, Manuela F. Almeida, Élia J. Pinto, et al. "Implementing a Transition Program from Paediatric to Adult Services in Phenylketonuria: Results after Two Years of Follow-Up with an Adult Team." Nutrients 13, no. 3 (2021): 799. http://dx.doi.org/10.3390/nu13030799.

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We aimed to report the implementation of a phenylketonuria (PKU) transition program and study the effects of follow-up with an adult team on metabolic control, adherence, and loss of follow-up. Fifty-five PKU patients were analysed in the study periods (SP): 2 years before (SP1) and after the beginning of adult care (SP2). Retrospective data on metabolic control and number of clinic appointments were collected for each SP, and protein intakes were analysed. In SP2, three patients (6%) were lost to follow-up. There was a small but statistically significant increase in median number of annual bl

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Curto, John M., and Marisa C. Kozlowski. "Chemoselective Activation of sp3 vs sp2 C–H Bonds with Pd(II)." Journal of the American Chemical Society 137, no. 1 (2014): 18–21. http://dx.doi.org/10.1021/ja5093166.

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Jones, Ella F., Deep K. Hathi, Julissa Molina-Vega, et al. "Abstract P3-02-02: FES-dedicated breast PET uptake in early-stage ER+ breast cancers." Cancer Research 82, no. 4_Supplement (2022): P3–02–02—P3–02–02. http://dx.doi.org/10.1158/1538-7445.sabcs21-p3-02-02.

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Abstract BACKGROUND: Patients with ER+ breast cancer may have a recurrence risk of aggressive disease. While clinical evidence suggests that ER+ tumors are responsive to endocrine therapy, up to one-third of patients with early-stage ER+ disease may not respond to endocrine therapy. Tumor biologic factors such as ER functionality, cell proliferation, and molecular traits may influence endocrine treatment responsiveness and long-term recurrence risk. More comprehensive tools are needed to depict the primary breast tumor. [18F]fluoroestradiol (FES) is a radiotracer developed for positron emissio

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Huang, Mingming, Man Tang, Jiefeng Hu, Stephen A. Westcott, Udo Radius, and Todd B. Marder. "Cu-mediated vs. Cu-free selective borylation of aryl alkyl sulfones." Chemical Communications 58, no. 3 (2022): 395–98. http://dx.doi.org/10.1039/d1cc06144e.

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Jones, Ella F., Deep K. Hathi, Natalia Konovalova, et al. "Abstract P3-02-01: Initial experience of FES-dedicated breast PET imaging of early-stage ER+ invasive lobular carcinoma." Cancer Research 82, no. 4_Supplement (2022): P3–02–01—P3–02–01. http://dx.doi.org/10.1158/1538-7445.sabcs21-p3-02-01.

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Abstract BACKGROUND: Invasive lobular carcinoma (ILC) is the second most common histological subtype of breast cancer, representing 15% of all invasive breast cancers. Most ILC tumors are estrogen receptor-positive (ER+) and may respond to endocrine therapy. However, tumor biologic factors such as ER functionality, cell proliferation, and molecular traits may influence endocrine treatment response and long-term recurrence risk, thus necessitating a comprehensive approach to characterize the primary breast tumor. [18F]fluoroestradiol (FES) is a radiotracer developed for positron emission tomogr

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Paleti, Swathi, Zain A. Sobani, Thomas R. McCarty, et al. "Impact of COVID-19 on gastroenterology fellowship training: a multicenter analysis of endoscopy volumes." Endoscopy International Open 09, no. 10 (2021): E1572—E1578. http://dx.doi.org/10.1055/a-1526-1419.

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Abstract Background and study aims The COVID-19 pandemic has had a profound impact on gastroenterology training programs. We aimed to objectively evaluate procedural training volume and impact of COVID-19 on gastroenterology fellowship programs in the United States. Methods This was a retrospective, multicenter study. Procedure volume data on upper and lower endoscopies performed by gastroenterology fellows was abstracted directly from the electronic medical record. The study period was stratified into 2 time periods: Study Period 1, SP1 (03/15/2020 to 06/30/2020) and Study Period 2, SP2 (07/0

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Zucca, Antonio, Sergio Stoccoro, Maria Agostina Cinellu, Giovanni Minghetti, and Mario Manassero. "Cyclometallated derivatives of rhodium(III). Activation of C(sp3)–H vs. C(sp2)–H bonds." Journal of the Chemical Society, Dalton Transactions, no. 19 (1999): 3431–37. http://dx.doi.org/10.1039/a903614h.

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Zang, Zhong-Lin, Sheng Zhao, Shuklachary Karnakanti, Cheng-Lin Liu, Pan-Lin Shao, and Yun He. "Catalytic Multisite-Selective Acetoxylation Reactions at sp2 vs sp3 C–H Bonds in Cyclic Olefins." Organic Letters 18, no. 19 (2016): 5014–17. http://dx.doi.org/10.1021/acs.orglett.6b02458.

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Basu, Amrita B., Saumya Umashankar, Denise M. Wolf, et al. "Evaluation of drug tolerability as a function of toxicity and quality of life in patients enrolled on I-SPY2." Journal of Clinical Oncology 42, no. 16_suppl (2024): 11113. http://dx.doi.org/10.1200/jco.2024.42.16_suppl.11113.

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11113 Background: Patient-reported outcomes (PROs) are valuable for understanding treatment tolerability and toxicity. I-SPY2 is a phase-II neoadjuvant clinical trial for breast cancer with electronic PROs and quality of life (QOL) assessments. We sought to understand how well the GP5 self-reported tolerability item reflected toxicity burden and QOL during treatment and follow-up in I-SPY 2 participants. Methods: Our study included 306 patients who completed the FACIT Item GP5 and answered PROMIS surveys at two or more timepoints. Analysis timepoints included screening (SC), inter-regimen (IR)

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Goreninskii, Semen, Yuri Yuriev, Artem Runts та ін. "Pulsed Vacuum Arc Deposition of Nitrogen-Doped Diamond-like Coatings for Long-Term Hydrophilicity of Electrospun Poly(ε-caprolactone) Scaffolds". Membranes 12, № 11 (2022): 1080. http://dx.doi.org/10.3390/membranes12111080.

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The surface hydrophobicity of poly(ε-caprolactone) electrospun scaffolds prevents their interactions with cells and tissue integration. Although plasma treatment of scaffolds enhances their hydrophilicity, this effect is temporary, and the hydrophobicity of the scaffolds is restored in about 30 days. In this communication, we report a method for hydrophilization of poly(ε-caprolactone) electrospun scaffolds for more than 6 months. To that end, diamond-like coating was deposited on the surface of the scaffolds in a nitrogen atmosphere using pulsed vacuum arc deposition with sputtering of graphi

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Wolf, Denise M., Christina Yau, Julia Wulfkuhle, et al. "Abstract PD5-04: PD5-04 Characterizing the HER2-/Immune-/DNA repair (DRD-) response predictive breast cancer subtype: the hunt for new protein targets in a high-needs population with low response to all I-SPY2 agents." Cancer Research 83, no. 5_Supplement (2023): PD5–04—PD5–04. http://dx.doi.org/10.1158/1538-7445.sabcs22-pd5-04.

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Abstract Background: In previous work we leveraged the I-SPY2 trial to create treatment response predictive subtypes (RPS) incorporating tumor biology beyond clinical HR/HER2, to better predict drug responses in an expanded treatment landscape that includes platinum agents, dual HER2-targeting regimens and immunotherapy [1]. We showed that best performing schemas incorporate Immune, DRD and HER2/Luminal phenotypes, and that treatment allocation based on these would increase the overall pCR rate to 63% from 51% using HR/HER2-based treatment selection. The RPS schema has been selected for prospe

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Cobain, Erin Frances, Lajos Pusztai, Cathy Lynne Graham, et al. "Elucidating the immune active state of HR+HER2- MammaPrint High 2 early breast cancer." Journal of Clinical Oncology 42, no. 16_suppl (2024): 506. http://dx.doi.org/10.1200/jco.2024.42.16_suppl.506.

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506 Background: The 70-gene signature, MammaPrint (MP), classifies patients (pts) with early-stage breast cancer (EBC) as having an UltraLow, Low, High 1 (H1), or High 2 (H2) risk of distant recurrence. I-SPY 2 showed that pts with MP H2, HR+HER2- tumors have significantly higher response rates to neoadjuvant chemotherapy + immunotherapy relative to pts with MP H1 tumors. Expression-based immune deconvolution provides more detailed information about immune cell function beyond conventional methods enumerating tumor infiltrating lymphocytes. To elucidate the underlying biology that mediates imm

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Hoȧi, Phạm Thị. "A Lonely Stroke That Slanted the Sky." Journal of Vietnamese Studies 16, no. 3 (2021): 122–28. http://dx.doi.org/10.1525/vs.2021.16.3.122.

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Pérez-Marín, Carlos Carmelo, Ander Arando, Francisco Maroto-Molina, Alberto Marín, and Juan Vicente Delgado. "Las subpoblaciones de espermatozoides y su calidad en fracciones producidas por la centrifugación de una sola capa en muestras frescas y normospérmicas de esperma de cordero." Revista Mexicana de Ciencias Pecuarias 12, no. 2 (2021): 386–401. http://dx.doi.org/10.22319/rmcp.v12i2.5683.

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Single layer centrifugation (SLC) technique has been developed to select the best sperm population in the ejaculate in order to increase the fertilization rates by artificial insemination or in vitro fertilization. Normospermic ram semen samples containing 800 and 3,000 × 106 sperms/ml (C800 and C3000, respectively) were processed by SLC. Three sperm fractions were separated in each sample following silica-coloidal sperm centrifugation and sperm yield, quality and subpopulations were analyzed in each one. In C800 group, the sperm recovery rate did not vary in any studied fraction, but when sam

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Schlaf, Marcel, Alan J. Lough та Robert H. Morris. "Dihydrogen Thiolate vs Hydride Thiol: Reactivity of the Series of Complexes MH(CO)(L)(PPh3)2(M = Ru, Os; L = Pyridine-2-thiolate, Quinoline-8-thiolate) with Acid. X-ray Structure Determination of [Os(CO)(μ2-Spy)(SpyH)(PPh3)]2[BF4]2". Organometallics 15, № 21 (1996): 4423–36. http://dx.doi.org/10.1021/om960411h.

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